NEURL3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of T-helper 1 cell differentiation (GO:0045625)6.30920818
2regulation of chronic inflammatory response (GO:0002676)6.10294792
3regulation of vitamin D biosynthetic process (GO:0060556)5.64017899
4antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.60637268
5positive regulation of gamma-delta T cell activation (GO:0046645)5.23206662
6regulation of cytokine secretion involved in immune response (GO:0002739)4.99273549
7regulation of vitamin metabolic process (GO:0030656)4.60056360
8regulation of B cell receptor signaling pathway (GO:0050855)4.40251071
9positive regulation of type 2 immune response (GO:0002830)4.26091319
10regulation of gamma-delta T cell differentiation (GO:0045586)4.17184298
11regulation of interleukin-12 biosynthetic process (GO:0045075)4.14984242
12positive regulation of chemokine biosynthetic process (GO:0045080)4.13952621
13tolerance induction (GO:0002507)4.11360420
14antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.10820578
15antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.10820578
16regulation of gamma-delta T cell activation (GO:0046643)4.10075036
17regulation of podosome assembly (GO:0071801)4.09784591
18branching involved in labyrinthine layer morphogenesis (GO:0060670)4.09183948
19lipopolysaccharide-mediated signaling pathway (GO:0031663)4.09141607
20antigen processing and presentation of endogenous antigen (GO:0019883)4.04869506
21T-helper 1 type immune response (GO:0042088)4.01803381
22mature B cell differentiation involved in immune response (GO:0002313)4.00171446
23negative regulation of viral genome replication (GO:0045071)3.94244346
24regulation of immunoglobulin secretion (GO:0051023)3.94073392
25positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)3.90028291
26regulation of dendritic cell antigen processing and presentation (GO:0002604)3.89600607
27mature B cell differentiation (GO:0002335)3.88326436
28regulation of chemokine biosynthetic process (GO:0045073)3.84013121
29response to muramyl dipeptide (GO:0032495)3.83842977
30interferon-gamma production (GO:0032609)3.82133232
31positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.78147260
32NIK/NF-kappaB signaling (GO:0038061)3.75236842
33positive regulation of heterotypic cell-cell adhesion (GO:0034116)3.74898005
34leukocyte aggregation (GO:0070486)3.74181594
35indole-containing compound catabolic process (GO:0042436)3.72284619
36indolalkylamine catabolic process (GO:0046218)3.72284619
37tryptophan catabolic process (GO:0006569)3.72284619
38kynurenine metabolic process (GO:0070189)3.71568318
39regulation of T-helper cell differentiation (GO:0045622)3.71401289
40positive regulation of T-helper cell differentiation (GO:0045624)3.69249600
41positive regulation of interleukin-12 production (GO:0032735)3.64571649
42positive regulation of B cell differentiation (GO:0045579)3.63376589
43regulation of interleukin-12 production (GO:0032655)3.62323550
44negative regulation of cytokine production involved in immune response (GO:0002719)3.60676881
45regulation of mononuclear cell migration (GO:0071675)3.60462944
46regulation of interferon-beta biosynthetic process (GO:0045357)3.60241977
47immunoglobulin mediated immune response (GO:0016064)3.58580775
48response to interleukin-15 (GO:0070672)3.56821988
49regulation of heat generation (GO:0031650)3.52293140
50negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.49432118
51positive regulation by symbiont of host defense response (GO:0052509)3.47968975
52modulation by symbiont of host defense response (GO:0052031)3.47968975
53modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.47968975
54modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.47968975
55positive regulation by organism of defense response of other organism involved in symbiotic interact3.47968975
56modulation by symbiont of host immune response (GO:0052553)3.47968975
57negative regulation of cell killing (GO:0031342)3.47837985
58negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.47837985
59positive regulation of cAMP-mediated signaling (GO:0043950)3.47041945
60cellular response to interleukin-15 (GO:0071350)3.46794414
61positive regulation of NF-kappaB import into nucleus (GO:0042346)3.45858125
62regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)3.44411246
63positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)3.43675809
64positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.43617937
65myeloid dendritic cell activation (GO:0001773)3.42206075
66lymph node development (GO:0048535)3.41136998
67regulation of B cell differentiation (GO:0045577)3.41116366
68cellular extravasation (GO:0045123)3.39056865
69negative regulation of nitric oxide biosynthetic process (GO:0045019)3.35776207
70negative regulation of inflammatory response to antigenic stimulus (GO:0002862)3.35692086
71regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)3.33944680
72regulation of type 2 immune response (GO:0002828)3.32687374
73positive regulation of interferon-gamma biosynthetic process (GO:0045078)3.32423316
74regulation of type I interferon-mediated signaling pathway (GO:0060338)3.32367126
75activation of MAPKKK activity (GO:0000185)3.30578156
76positive regulation of defense response to virus by host (GO:0002230)3.30012151
77positive regulation of nitric oxide biosynthetic process (GO:0045429)3.28393356
78B cell receptor signaling pathway (GO:0050853)3.26810916
79myeloid dendritic cell differentiation (GO:0043011)3.25347888
80cellular response to interferon-gamma (GO:0071346)3.24700705
81neutrophil activation (GO:0042119)3.23440403
82regulation of antigen processing and presentation (GO:0002577)3.21065658
83regulation of nitric oxide biosynthetic process (GO:0045428)3.20858269
84neutrophil activation involved in immune response (GO:0002283)3.20450595
85regulation of inflammatory response to antigenic stimulus (GO:0002861)3.20387561
86cellular response to interferon-alpha (GO:0035457)3.20083744
87negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)3.19838907
88response to type I interferon (GO:0034340)3.18445515
89germinal center formation (GO:0002467)3.17702009
90regulation of interferon-gamma biosynthetic process (GO:0045072)3.17333700
91regulation of T-helper 1 type immune response (GO:0002825)3.16893931
92positive regulation of interferon-alpha production (GO:0032727)3.15048762
93negative regulation of bone resorption (GO:0045779)3.13057210
94regulation of interleukin-8 biosynthetic process (GO:0045414)3.11685715
95modulation of growth of symbiont involved in interaction with host (GO:0044144)3.11124618
96regulation of growth of symbiont in host (GO:0044126)3.11124618
97negative regulation of growth of symbiont in host (GO:0044130)3.11124618
98negative regulation of growth of symbiont involved in interaction with host (GO:0044146)3.11124618
99monocyte chemotaxis (GO:0002548)3.10427790
100cellular response to lipopolysaccharide (GO:0071222)3.10114466
101interferon-gamma-mediated signaling pathway (GO:0060333)3.09122002
102antigen processing and presentation via MHC class Ib (GO:0002475)3.09081352
103granulocyte activation (GO:0036230)3.08945663
104negative regulation of amino acid transport (GO:0051956)3.08847498
105positive thymic T cell selection (GO:0045059)3.08614046
106response to interferon-gamma (GO:0034341)3.08133057
107T cell migration (GO:0072678)3.07043465
108megakaryocyte development (GO:0035855)3.06628164
109B cell homeostasis (GO:0001782)3.05278987
110type I interferon signaling pathway (GO:0060337)3.04876273
111cellular response to type I interferon (GO:0071357)3.04876273
112regulation of interferon-alpha production (GO:0032647)3.04662483
113regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.04546826
114regulation of RIG-I signaling pathway (GO:0039535)3.03903908
115regulation of membrane protein ectodomain proteolysis (GO:0051043)3.03561666
116positive regulation of inflammatory response to antigenic stimulus (GO:0002863)3.03552584
117positive regulation of antigen processing and presentation (GO:0002579)3.02262133
118CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)3.01595488
119T-helper cell differentiation (GO:0042093)3.01595488
120regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.00918736
121leukocyte cell-cell adhesion (GO:0007159)3.00148334
122cellular response to nicotine (GO:0071316)2.99885113
123cellular response to molecule of bacterial origin (GO:0071219)2.99172173
124definitive hemopoiesis (GO:0060216)2.98957035
125negative regulation of lipid storage (GO:0010888)2.98576496
126regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.97390831
127cellular response to exogenous dsRNA (GO:0071360)2.96864606
128hepatocyte apoptotic process (GO:0097284)2.96656472
129defense response to protozoan (GO:0042832)2.96328631
130cellular response to interferon-beta (GO:0035458)2.96287710
131lymphocyte chemotaxis (GO:0048247)2.96261250
132negative regulation of erythrocyte differentiation (GO:0045647)2.95731077
133cellular biogenic amine catabolic process (GO:0042402)2.95709033
134amine catabolic process (GO:0009310)2.95709033
135positive regulation of natural killer cell differentiation (GO:0032825)2.94699426
136interferon-gamma secretion (GO:0072643)2.94345075
137Arp2/3 complex-mediated actin nucleation (GO:0034314)2.93960837
138positive regulation of acute inflammatory response (GO:0002675)2.93734032
139regulation of NF-kappaB import into nucleus (GO:0042345)2.93214342
140negative regulation of myeloid cell apoptotic process (GO:0033033)2.93147606
141regulation of heterotypic cell-cell adhesion (GO:0034114)2.92269228
142negative regulation of granulocyte differentiation (GO:0030853)2.91936139
143tryptophan metabolic process (GO:0006568)2.91241996
144response to protozoan (GO:0001562)2.89259281
145lymphocyte homeostasis (GO:0002260)2.82614938
146JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.80633212
147dendritic cell chemotaxis (GO:0002407)2.79751057
148dendritic cell differentiation (GO:0097028)2.79531060
149negative thymic T cell selection (GO:0045060)2.78564116
150macrophage activation involved in immune response (GO:0002281)2.75906021
151positive regulation of heat generation (GO:0031652)2.74422215
152negative T cell selection (GO:0043383)2.73908492
153dendritic cell migration (GO:0036336)2.73806126
154T cell homeostasis (GO:0043029)2.73604379
155negative regulation of interleukin-12 production (GO:0032695)2.71933464
156response to peptidoglycan (GO:0032494)2.71844523
157myeloid cell activation involved in immune response (GO:0002275)2.69381100
158mast cell activation (GO:0045576)2.67181950
159positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.66030195
160B cell mediated immunity (GO:0019724)2.65089415
161respiratory burst (GO:0045730)2.64935947
162T cell activation involved in immune response (GO:0002286)2.64040496
163angiogenesis involved in wound healing (GO:0060055)2.63865107
164regulation of erythrocyte differentiation (GO:0045646)2.63754561
165regulation of cell killing (GO:0031341)2.61998818
166alpha-beta T cell differentiation involved in immune response (GO:0002293)2.60645856
167alpha-beta T cell activation involved in immune response (GO:0002287)2.60645856
168T cell differentiation involved in immune response (GO:0002292)2.60645856
169regulation of mast cell activation (GO:0033003)2.60507104
170regulation of T cell receptor signaling pathway (GO:0050856)2.60423365
171leukocyte homeostasis (GO:0001776)2.59576349
172regulation of fever generation (GO:0031620)2.59530608
173positive regulation of interferon-beta production (GO:0032728)2.58138110
174positive regulation of B cell activation (GO:0050871)2.56773250
175negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.56556275
176myeloid leukocyte activation (GO:0002274)2.56102703

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human5.34270942
2IRF8_22096565_ChIP-ChIP_GC-B_Human5.01532646
3FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.98055293
4STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.73955331
5IRF8_21731497_ChIP-ChIP_J774_Mouse3.76979552
6MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.75434225
7SCL_19346495_ChIP-Seq_HPC-7_Human3.71928697
8IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.57388361
9* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.34511594
10GATA1_22025678_ChIP-Seq_K562_Human3.29033404
11STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.17096107
12* IRF8_27001747_Chip-Seq_BMDM_Mouse3.14498784
13IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.12912840
14* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.94580251
15RUNX_20019798_ChIP-Seq_JUKART_Human2.73596042
16MYB_21317192_ChIP-Seq_ERMYB_Mouse2.72537259
17STAT4_19710469_ChIP-ChIP_TH1__Mouse2.72401526
18SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.72051595
19EGR1_19374776_ChIP-ChIP_THP-1_Human2.69583361
20* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.67832399
21* RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.64739687
22MYB_26560356_Chip-Seq_TH2_Human2.43528077
23MAF_26560356_Chip-Seq_TH1_Human2.25149198
24NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.23752848
25MYC_22102868_ChIP-Seq_BL_Human2.21223906
26RUNX1_22412390_ChIP-Seq_EML_Mouse2.20739310
27SPI1_23547873_ChIP-Seq_NB4_Human2.17769661
28Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.16268016
29MYB_26560356_Chip-Seq_TH1_Human2.15104271
30RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.12886350
31NOTCH1_21737748_ChIP-Seq_TLL_Human2.10853760
32* BRD4_27068464_Chip-Seq_AML-cells_Mouse2.10382050
33VDR_21846776_ChIP-Seq_THP-1_Human2.03354887
34VDR_24763502_ChIP-Seq_THP-1_Human2.00297931
35SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.99369196
36* ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.97740267
37TCF7_22412390_ChIP-Seq_EML_Mouse1.88968983
38* LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.84864141
39UTX_26944678_Chip-Seq_JUKART_Human1.83032212
40* LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.82926865
41* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.81654425
42TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.81046958
43E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.80620623
44NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.77197128
45GATA1_19941827_ChIP-Seq_MEL_Mouse1.72439947
46* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.70279047
47SPI1_23127762_ChIP-Seq_K562_Human1.68141436
48GATA2_21666600_ChIP-Seq_HMVEC_Human1.66627233
49GATA2_22383799_ChIP-Seq_G1ME_Mouse1.66559821
50TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.65354201
51* GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.59746863
52* PU_27001747_Chip-Seq_BMDM_Mouse1.56995165
53VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.52889754
54* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.52435844
55STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.50802820
56GATA1_19941826_ChIP-Seq_K562_Human1.49478527
57* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.48169002
58ESR1_21235772_ChIP-Seq_MCF-7_Human1.44709728
59ESR2_21235772_ChIP-Seq_MCF-7_Human1.44568019
60GATA2_19941826_ChIP-Seq_K562_Human1.38452068
61SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.37865304
62* GATA3_27048872_Chip-Seq_THYMUS_Human1.36492123
63FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.33293219
64TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.31799317
65MAF_26560356_Chip-Seq_TH2_Human1.30269584
66PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.29817647
67STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.29108209
68SMAD_19615063_ChIP-ChIP_OVARY_Human1.26534978
69STAT1_20625510_ChIP-Seq_HELA_Human1.24173157
70VDR_24787735_ChIP-Seq_THP-1_Human1.23054219
71PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.22151055
72TP63_17297297_ChIP-ChIP_HaCaT_Human1.19862567
73KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.19758407
74CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.18855593
75SOX2_20726797_ChIP-Seq_SW620_Human1.13908970
76KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.12901960
77TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.11935047
78KDM2B_26808549_Chip-Seq_SUP-B15_Human1.09673054
79CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.08929148
80VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.07808880
81FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.07280180
82RXR_22158963_ChIP-Seq_LIVER_Mouse1.06873941
83THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.06080634
84ELK3_25401928_ChIP-Seq_HUVEC_Human1.05958373
85* GATA3_26560356_Chip-Seq_TH2_Human1.05260387
86JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.04828376
87* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.01679399
88LXR_22158963_ChIP-Seq_LIVER_Mouse0.99777053
89KDM2B_26808549_Chip-Seq_DND41_Human0.97811287
90HOXB4_20404135_ChIP-ChIP_EML_Mouse0.97665472
91GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.96857925
92JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.96640282
93RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.95903603
94CDX2_20551321_ChIP-Seq_CACO-2_Human0.95482222
95ELF1_17652178_ChIP-ChIP_JURKAT_Human0.94761742
96SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.94575048
97SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.94486579
98EGR1_23403033_ChIP-Seq_LIVER_Mouse0.94346406
99NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.94133849
100ERG_20887958_ChIP-Seq_HPC-7_Mouse0.91873030
101CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.91830882
102CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.91103349
103NCOR1_26117541_ChIP-Seq_K562_Human0.90550069
104PPARA_22158963_ChIP-Seq_LIVER_Mouse0.86551519
105TFEB_21752829_ChIP-Seq_HELA_Human0.81986911
106EGR1_19032775_ChIP-ChIP_M12_Human0.80488679
107ETS1_22383799_ChIP-Seq_G1ME_Mouse0.79943699
108PU.1_20513432_ChIP-Seq_Bcells_Mouse0.79611766
109BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.77573013
110PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.76803402
111IKZF1_21737484_ChIP-ChIP_HCT116_Human0.75806936
112STAT3_1855785_ChIP-Seq_MESCs_Mouse0.74849173
113ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.73994214
114CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.73927377
115SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.72556877
116SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.72556877
117* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.72424374
118KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.71080820
119KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.71080820
120KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.71080820
121PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.70997704
122FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.67586612
123* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.66438651
124CIITA_25753668_ChIP-Seq_RAJI_Human0.66128798
125SMRT_27268052_Chip-Seq_Bcells_Human0.65069991
126GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.64586445
127* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.64135954
128BCOR_27268052_Chip-Seq_Bcells_Human0.63890595

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation3.79894647
2MP0005671_abnormal_response_to3.19996143
3MP0002139_abnormal_hepatobiliary_system3.19727247
4MP0000685_abnormal_immune_system3.14217970
5MP0003436_decreased_susceptibility_to3.09784187
6MP0001790_abnormal_immune_system3.08928724
7MP0005387_immune_system_phenotype3.08928724
8MP0009785_altered_susceptibility_to3.08067544
9MP0001800_abnormal_humoral_immune3.04747503
10MP0005000_abnormal_immune_tolerance2.83618069
11MP0002452_abnormal_antigen_presenting2.76526707
12MP0002723_abnormal_immune_serum2.67158097
13MP0002419_abnormal_innate_immunity2.60309828
14MP0005025_abnormal_response_to2.59382931
15MP0002148_abnormal_hypersensitivity_rea2.59036164
16MP0002420_abnormal_adaptive_immunity2.55564979
17MP0001819_abnormal_immune_cell2.54959727
18MP0003724_increased_susceptibility_to2.46391604
19MP0005464_abnormal_platelet_physiology2.40022776
20MP0010155_abnormal_intestine_physiology2.38412658
21MP0001873_stomach_inflammation2.36438879
22MP0003303_peritoneal_inflammation2.35549976
23MP0004510_myositis2.32283476
24MP0003763_abnormal_thymus_physiology2.29284284
25MP0002398_abnormal_bone_marrow2.19492829
26MP0002405_respiratory_system_inflammati2.13567769
27MP0003300_gastrointestinal_ulcer2.10946658
28MP0004947_skin_inflammation2.07215836
29MP0000716_abnormal_immune_system2.04303611
30MP0003866_abnormal_defecation2.03268484
31MP0000465_gastrointestinal_hemorrhage2.00550626
32MP0002396_abnormal_hematopoietic_system1.95873336
33MP0003195_calcinosis1.94252007
34MP0006082_CNS_inflammation1.93904987
35MP0009278_abnormal_bone_marrow1.93652985
36MP0008004_abnormal_stomach_pH1.92325923
37MP0001853_heart_inflammation1.90792558
38MP0001545_abnormal_hematopoietic_system1.89201235
39MP0005397_hematopoietic_system_phenotyp1.89201235
40MP0001845_abnormal_inflammatory_respons1.87890119
41MP0000689_abnormal_spleen_morphology1.87486769
42MP0000490_abnormal_crypts_of1.82244223
43MP0005451_abnormal_body_composition1.81683709
44MP0002722_abnormal_immune_system1.81089847
45MP0004808_abnormal_hematopoietic_stem1.77749341
46MP0002429_abnormal_blood_cell1.73347006
47MP0002332_abnormal_exercise_endurance1.72630426
48MP0005310_abnormal_salivary_gland1.69157926
49MP0002166_altered_tumor_susceptibility1.66416776
50MP0009333_abnormal_splenocyte_physiolog1.63244817
51MP0001533_abnormal_skeleton_physiology1.61759297
52MP0003183_abnormal_peptide_metabolism1.54403001
53MP0002277_abnormal_respiratory_mucosa1.54350222
54MP0005174_abnormal_tail_pigmentation1.48018154
55MP0002933_joint_inflammation1.43775622
56MP0008469_abnormal_protein_level1.39217447
57MP0002006_tumorigenesis1.38987817
58MP0003806_abnormal_nucleotide_metabolis1.38560013
59MP0009764_decreased_sensitivity_to1.38247235
60MP0000703_abnormal_thymus_morphology1.37719535
61MP0005058_abnormal_lysosome_morphology1.32201859
62MP0001501_abnormal_sleep_pattern1.26984169
63MP0003690_abnormal_glial_cell1.23736106
64MP0000858_altered_metastatic_potential1.20556217
65MP0003191_abnormal_cellular_cholesterol1.19363057
66MP0003656_abnormal_erythrocyte_physiolo1.18534501
67MP0002138_abnormal_hepatobiliary_system1.15854006
68MP0003448_altered_tumor_morphology1.14676850
69MP0000343_altered_response_to1.13269155
70MP0000604_amyloidosis1.12987533
71MP0002132_abnormal_respiratory_system1.12357476
72MP0003828_pulmonary_edema1.06494879
73MP0002998_abnormal_bone_remodeling1.05821577
74MP0001851_eye_inflammation1.05117865
75MP0003172_abnormal_lysosome_physiology1.04086925
76MP0004147_increased_porphyrin_level1.02135604
77MP0001663_abnormal_digestive_system1.00319097
78MP0005075_abnormal_melanosome_morpholog0.96346086
79MP0003646_muscle_fatigue0.96076575
80MP0005165_increased_susceptibility_to0.94959436
81MP0009840_abnormal_foam_cell0.94864038
82MP0000569_abnormal_digit_pigmentation0.90011253
83MP0005164_abnormal_response_to0.88539814
84MP0002163_abnormal_gland_morphology0.86109009
85MP0009763_increased_sensitivity_to0.86012032
86MP0005166_decreased_susceptibility_to0.85819989
87MP0006054_spinal_hemorrhage0.84428596
88MP0009765_abnormal_xenobiotic_induced0.81249945
89MP0002693_abnormal_pancreas_physiology0.80385638
90MP0000015_abnormal_ear_pigmentation0.79898916
91MP0004264_abnormal_extraembryonic_tissu0.79261413
92MP0000477_abnormal_intestine_morphology0.79016571
93MP0005535_abnormal_body_temperature0.78884875
94MP0000249_abnormal_blood_vessel0.78882717
95MP0005647_abnormal_sex_gland0.78752960
96MP0001542_abnormal_bone_strength0.78409394
97MP0003453_abnormal_keratinocyte_physiol0.78409125
98MP0010307_abnormal_tumor_latency0.76075956
99MP0002837_dystrophic_cardiac_calcinosis0.75922466
100MP0003943_abnormal_hepatobiliary_system0.72905076
101MP0005390_skeleton_phenotype0.70862468
102MP0002136_abnormal_kidney_physiology0.70623385
103MP0005167_abnormal_blood-brain_barrier0.69523145
104MP0003091_abnormal_cell_migration0.68998804
105MP0005379_endocrine/exocrine_gland_phen0.68137604
106MP0003795_abnormal_bone_structure0.67703457
107MP0002254_reproductive_system_inflammat0.67230419
108MP0002928_abnormal_bile_duct0.66959244
109MP0008874_decreased_physiological_sensi0.66611118
110MP0003075_altered_response_to0.66569221
111MP0002095_abnormal_skin_pigmentation0.65929461
112MP0008007_abnormal_cellular_replicative0.65824408
113MP0005266_abnormal_metabolism0.65113064
114MP0001191_abnormal_skin_condition0.64878650
115MP0000920_abnormal_myelination0.64625048
116MP0000609_abnormal_liver_physiology0.64408275
117MP0002019_abnormal_tumor_incidence0.63350011
118MP0005365_abnormal_bile_salt0.62290203
119MP0004043_abnormal_pH_regulation0.61138932
120MP0003566_abnormal_cell_adhesion0.60461726
121MP0004782_abnormal_surfactant_physiolog0.59461408
122MP0005319_abnormal_enzyme/_coenzyme0.59326018
123MP0010352_gastrointestinal_tract_polyps0.59167258
124MP0003186_abnormal_redox_activity0.56968900
125MP0003045_fibrosis0.56867708
126MP0002877_abnormal_melanocyte_morpholog0.56274447
127MP0001764_abnormal_homeostasis0.55983811
128MP0005381_digestive/alimentary_phenotyp0.53398602
129MP0004883_abnormal_blood_vessel0.53338747
130MP0005023_abnormal_wound_healing0.53102725
131MP0005448_abnormal_energy_balance0.51199619

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of liposaccharide metabolism (HP:0010968)6.34110423
2Abnormality of glycosphingolipid metabolism (HP:0004343)6.34110423
3Abnormality of glycolipid metabolism (HP:0010969)6.34110423
4Myositis (HP:0100614)5.55657086
5Optic neuritis (HP:0100653)4.95869157
6Retrobulbar optic neuritis (HP:0100654)4.95869157
7Recurrent abscess formation (HP:0002722)4.94989049
8Orchitis (HP:0100796)4.85583072
9Eczematoid dermatitis (HP:0000976)4.72906296
10Recurrent bacterial skin infections (HP:0005406)4.52538951
11Elevated erythrocyte sedimentation rate (HP:0003565)4.36939260
12Loss of speech (HP:0002371)4.30626746
13Dysostosis multiplex (HP:0000943)4.30209234
14IgM deficiency (HP:0002850)4.07421682
15Disinhibition (HP:0000734)4.05384751
16Petechiae (HP:0000967)4.02506535
17Recurrent fungal infections (HP:0002841)4.00876241
18Abnormality of glycosaminoglycan metabolism (HP:0004371)3.58368623
19Abnormality of mucopolysaccharide metabolism (HP:0011020)3.58368623
20Abnormality of polysaccharide metabolism (HP:0011012)3.58368623
21Increased IgM level (HP:0003496)3.58134687
22Nuclear cataract (HP:0100018)3.56324983
23Vasculitis (HP:0002633)3.55229146
24Prolonged bleeding time (HP:0003010)3.50742009
25Pustule (HP:0200039)3.49118181
26Recurrent viral infections (HP:0004429)3.47228018
27Mutism (HP:0002300)3.44639553
28Inflammation of the large intestine (HP:0002037)3.44503525
29Stomatitis (HP:0010280)3.40766276
30Urinary glycosaminoglycan excretion (HP:0003541)3.38059457
31Mucopolysacchariduria (HP:0008155)3.38059457
32Autoimmune thrombocytopenia (HP:0001973)3.34936696
33Colitis (HP:0002583)3.29831544
34Abnormality of macrophages (HP:0004311)3.26795263
35Keratoconjunctivitis sicca (HP:0001097)3.26520580
36Abnormal delayed hypersensitivity skin test (HP:0002963)3.26085438
37Recurrent skin infections (HP:0001581)3.24787446
38Gastrointestinal inflammation (HP:0004386)3.24651042
39Parakeratosis (HP:0001036)3.23591644
40Tetraparesis (HP:0002273)3.20734659
41Meningitis (HP:0001287)3.17091813
42Mediastinal lymphadenopathy (HP:0100721)3.14345602
43Recurrent cutaneous fungal infections (HP:0011370)3.13613482
44Chronic mucocutaneous candidiasis (HP:0002728)3.13613482
45Gangrene (HP:0100758)3.12452265
46Chronic diarrhea (HP:0002028)3.12131652
47Pulmonary infiltrates (HP:0002113)3.11813488
48Thrombocytosis (HP:0001894)3.08603910
49Arterial thrombosis (HP:0004420)3.08051849
50Recurrent gram-negative bacterial infections (HP:0005420)3.00925515
51Keratoconjunctivitis (HP:0001096)2.96242891
52Chronic obstructive pulmonary disease (HP:0006510)2.96023281
53Obstructive lung disease (HP:0006536)2.96023281
54Prostate neoplasm (HP:0100787)2.94969176
55Chronic otitis media (HP:0000389)2.93462057
56Impaired platelet aggregation (HP:0003540)2.92226319
57Abnormal platelet function (HP:0011869)2.92226319
58Cellulitis (HP:0100658)2.89271791
59Thyroiditis (HP:0100646)2.87427578
60Glomerulonephritis (HP:0000099)2.85574984
61Progressive neurologic deterioration (HP:0002344)2.82451427
62Recurrent bronchitis (HP:0002837)2.81218969
63Gastrointestinal stroma tumor (HP:0100723)2.81087737
64Spontaneous hematomas (HP:0007420)2.81015603
65Agammaglobulinemia (HP:0004432)2.80819883
66Encephalitis (HP:0002383)2.80509109
67Epistaxis (HP:0000421)2.80123880
68Panhypogammaglobulinemia (HP:0003139)2.79412304
69Abnormality of the fingertips (HP:0001211)2.78790595
70Abnormality of T cell physiology (HP:0011840)2.75714762
71Interstitial pulmonary disease (HP:0006530)2.74925715
72Abnormality of T cells (HP:0002843)2.74341336
73Hemoptysis (HP:0002105)2.73766424
74Basal ganglia calcification (HP:0002135)2.73228625
75Vacuolated lymphocytes (HP:0001922)2.70274371
76Gingival bleeding (HP:0000225)2.69986058
77Leukocytosis (HP:0001974)2.67224760
78Gingivitis (HP:0000230)2.66986776
79Abnormality of the prostate (HP:0008775)2.66892751
80Joint swelling (HP:0001386)2.66492690
81Increased density of long bones (HP:0006392)2.65242266
82Increased serum ferritin (HP:0003281)2.64689700
83Osteomyelitis (HP:0002754)2.64612179
84Lymphopenia (HP:0001888)2.61056304
85Nausea (HP:0002018)2.59963382
86Periodontitis (HP:0000704)2.59895087
87Polyneuropathy (HP:0001271)2.58111332
88B lymphocytopenia (HP:0010976)2.55968652
89Abnormality of B cell number (HP:0010975)2.55968652
90Apathy (HP:0000741)2.53058638
91Nasal polyposis (HP:0100582)2.49538475
92Abnormality of cells of the lymphoid lineage (HP:0012140)2.49155565
93Increased neuronal autofluorescent lipopigment (HP:0002074)2.48866582
94T lymphocytopenia (HP:0005403)2.48781377
95Hypergammaglobulinemia (HP:0010702)2.48701592
96Neurofibrillary tangles (HP:0002185)2.47508966
97Abnormality of T cell number (HP:0011839)2.46008585
98Abnormality of the nasal mucosa (HP:0000433)2.45638641
99Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.45561228
100Increased cerebral lipofuscin (HP:0011813)2.42968512
101Diminished motivation (HP:0000745)2.41693923
102Persistence of primary teeth (HP:0006335)2.41214378
103Severe combined immunodeficiency (HP:0004430)2.40272023
104Increased IgE level (HP:0003212)2.37291300
105IgA deficiency (HP:0002720)2.36850485
106Abnormality of the pleura (HP:0002103)2.36660189
107Prolonged neonatal jaundice (HP:0006579)2.35877510
108Anorexia (HP:0002039)2.34888332
109Bilateral sensorineural hearing impairment (HP:0008619)2.34752440
110Inappropriate behavior (HP:0000719)2.32874005
111Hematochezia (HP:0002573)2.31741740
112Abnormality of eosinophils (HP:0001879)2.29988933
113Metaphyseal irregularity (HP:0003025)2.28306255
114IgG deficiency (HP:0004315)2.26965079
115Axonal loss (HP:0003447)2.25894051
116Malnutrition (HP:0004395)2.25666294
117Poikilocytosis (HP:0004447)2.24876326
118Systemic lupus erythematosus (HP:0002725)2.23613481
119Premature loss of primary teeth (HP:0006323)2.18630655
120Abnormality of iron homeostasis (HP:0011031)2.16437737
121Acanthocytosis (HP:0001927)2.15606062
122Combined immunodeficiency (HP:0005387)2.13975072
123Abnormal platelet volume (HP:0011876)2.13797169
124Abnormality of aromatic amino acid family metabolism (HP:0004338)2.13592921
125Acne (HP:0001061)2.12549197
126Eosinophilia (HP:0001880)2.11848929
127Gastrointestinal infarctions (HP:0005244)2.11649396
128Urticaria (HP:0001025)2.11036151
129Purpura (HP:0000979)2.10702023
130Cheilitis (HP:0100825)2.10601622
131Granulocytopenia (HP:0001913)2.09373823
132Abnormality of the pericardium (HP:0001697)2.06869666
133Chest pain (HP:0100749)2.05974495
134Memory impairment (HP:0002354)2.05505957
135Recurrent pneumonia (HP:0006532)2.05296992
136Mesangial abnormality (HP:0001966)2.05000409
137Arthralgia (HP:0002829)2.04382446
138Recurrent sinusitis (HP:0011108)2.04133567
139Vertigo (HP:0002321)2.03727320
140Glomerulopathy (HP:0100820)2.03133136
141Amyloidosis (HP:0011034)2.02925844
142Complement deficiency (HP:0004431)2.01543850
143Autoimmune hemolytic anemia (HP:0001890)2.00317479
144Abnormality of the basal ganglia (HP:0002134)1.99317086
145Agnosia (HP:0010524)1.99119959
146Generalized aminoaciduria (HP:0002909)1.98377618
147Pulmonary embolism (HP:0002204)1.98255179
148Acute myeloid leukemia (HP:0004808)1.94884251
149Keratitis (HP:0000491)1.94236747
150Neuronal loss in central nervous system (HP:0002529)1.93492868
151Abnormality of the vasculature of the conjunctiva (HP:0008054)1.91541746
152Hepatosplenomegaly (HP:0001433)1.91506645
153Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.91035238

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK3.94854912
2MAP4K13.86373945
3TAOK33.46279515
4MAP3K143.36323235
5IRAK33.35430083
6TAOK22.97550109
7TBK12.82780580
8DDR22.69784158
9IKBKE2.56314404
10TGFBR22.45155855
11IRAK42.30931799
12TYK22.29386522
13TEC2.24887891
14IKBKB2.22096382
15KIT2.21258019
16JAK32.17260360
17TAOK12.17138897
18BTK2.03052006
19BMPR21.96313018
20RIPK41.95664323
21ZAP701.87035867
22ITK1.83423270
23MAP3K111.81748390
24BLK1.79974374
25JAK11.78137157
26SYK1.65963704
27STK101.62999586
28GRK61.62160040
29CHUK1.60023310
30FGR1.59634518
31MOS1.59315688
32PIM11.57508966
33IRAK11.45127821
34CSF1R1.38827145
35MAP2K31.36669279
36HCK1.35838143
37CDC42BPA1.32867589
38RPS6KA41.25681206
39PRPF4B1.23163894
40LCK1.22875879
41MAP3K131.21526026
42MATK1.15941129
43ERN11.15330965
44CSK1.13666446
45EPHB11.10409722
46LYN1.07650866
47SIK31.05637700
48MAP3K101.04639260
49ACVR1B1.04169799
50EEF2K1.02600168
51MST41.02386070
52IRAK21.01855596
53FGFR31.00068696
54NEK90.99805213
55PIM20.99356304
56MAP3K50.97492527
57MARK30.91269515
58MAP3K10.90318876
59JAK20.89799640
60NLK0.86120691
61ABL20.84885683
62FES0.84706972
63FLT30.84647023
64EPHA30.81832663
65PKN10.81655878
66FGFR40.81491300
67DAPK20.80669818
68TIE10.77230156
69PRKG20.76719927
70STK240.75065963
71CLK10.74498459
72DAPK30.74111254
73MAPK150.73829023
74TLK10.73463235
75SIK20.69713129
76CDK120.66138647
77TGFBR10.66119894
78PTK60.65168630
79MAP2K60.63609028
80DYRK30.62441572
81TRPM70.60429743
82CDK60.58755278
83RPS6KA60.58534378
84MAP3K120.56431184
85YES10.56073208
86PIK3CG0.55354581
87CDK90.55353721
88MAP3K70.55100944
89MAP3K30.54743828
90BRD40.54734953
91LRRK20.54164315
92MAP2K20.53005156
93BMX0.52914237
94LMTK20.52107187
95STK40.51634773
96SGK30.51395591
97CAMK1D0.50426953
98ADRBK20.48083295
99EIF2AK10.47934752
100MAPKAPK20.47891919
101GRK70.47792383
102EIF2AK20.46997714
103TYRO30.46842670
104PRKCQ0.45340738
105RIPK10.44063516
106TSSK60.43589716
107RPS6KC10.41399339
108RPS6KL10.41399339
109DYRK1B0.40069716
110NUAK10.39947907
111HIPK20.39628383
112PRKAA20.39375460
113NME20.38497614
114ABL10.38330453
115PDK10.36364492
116LATS20.36021809
117MAPK40.33992334
118SGK20.32920364
119EGFR0.29796893
120CDK40.28597350
121PRKCD0.28455622
122MAPK30.28287018
123FRK0.28043173
124RPS6KA20.27149541
125MAPK110.26895173
126INSR0.25465930
127RPS6KA50.19700066
128TESK10.16580957
129DAPK10.15164244
130TNK20.14129018
131CAMKK20.12394044
132FER0.11132007
133ARAF0.10875546
134MAP4K20.08663044
135MAPK70.08429158
136GSK3A0.07831495
137CAMK2G0.06964830

Predicted pathways (KEGG)

RankGene SetZ-score
1Inflammatory bowel disease (IBD)_Homo sapiens_hsa053213.15052308
2NF-kappa B signaling pathway_Homo sapiens_hsa040642.85769656
3Leishmaniasis_Homo sapiens_hsa051402.83888863
4Osteoclast differentiation_Homo sapiens_hsa043802.74866627
5Primary immunodeficiency_Homo sapiens_hsa053402.61269626
6B cell receptor signaling pathway_Homo sapiens_hsa046622.52807480
7Intestinal immune network for IgA production_Homo sapiens_hsa046722.47415782
8Type I diabetes mellitus_Homo sapiens_hsa049402.35920915
9Measles_Homo sapiens_hsa051622.32397923
10Hematopoietic cell lineage_Homo sapiens_hsa046402.17181978
11RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.06577025
12Toll-like receptor signaling pathway_Homo sapiens_hsa046202.00349166
13NOD-like receptor signaling pathway_Homo sapiens_hsa046211.99025782
14Jak-STAT signaling pathway_Homo sapiens_hsa046301.88250380
15TNF signaling pathway_Homo sapiens_hsa046681.86636082
16Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.84090496
17Staphylococcus aureus infection_Homo sapiens_hsa051501.79138900
18T cell receptor signaling pathway_Homo sapiens_hsa046601.78935541
19Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.76824034
20Influenza A_Homo sapiens_hsa051641.69277142
21Legionellosis_Homo sapiens_hsa051341.67104017
22Antigen processing and presentation_Homo sapiens_hsa046121.67075809
23Toxoplasmosis_Homo sapiens_hsa051451.65106005
24Herpes simplex infection_Homo sapiens_hsa051681.61996269
25Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.61421697
26Allograft rejection_Homo sapiens_hsa053301.60512917
27Pertussis_Homo sapiens_hsa051331.52285269
28Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.51022522
29Apoptosis_Homo sapiens_hsa042101.50185114
30Tuberculosis_Homo sapiens_hsa051521.40121593
31Acute myeloid leukemia_Homo sapiens_hsa052211.39423552
32Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.39022663
33Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.35080068
34Other glycan degradation_Homo sapiens_hsa005111.32518636
35Chemokine signaling pathway_Homo sapiens_hsa040621.31605152
36Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.31256422
37Asthma_Homo sapiens_hsa053101.31037222
38Hepatitis B_Homo sapiens_hsa051611.29494695
39Graft-versus-host disease_Homo sapiens_hsa053321.29167312
40Leukocyte transendothelial migration_Homo sapiens_hsa046701.28233105
41Shigellosis_Homo sapiens_hsa051311.27644789
42Malaria_Homo sapiens_hsa051441.27363464
43Sulfur metabolism_Homo sapiens_hsa009201.23923638
44Transcriptional misregulation in cancer_Homo sapiens_hsa052021.13586880
45Hepatitis C_Homo sapiens_hsa051601.12933955
46Platelet activation_Homo sapiens_hsa046111.12437275
47Rheumatoid arthritis_Homo sapiens_hsa053231.11377842
48Prolactin signaling pathway_Homo sapiens_hsa049171.06127094
49Chronic myeloid leukemia_Homo sapiens_hsa052201.05982352
50Salmonella infection_Homo sapiens_hsa051321.05209263
51AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.00588851
52Caffeine metabolism_Homo sapiens_hsa002321.00455118
53Glycosaminoglycan degradation_Homo sapiens_hsa005310.98143418
54Tryptophan metabolism_Homo sapiens_hsa003800.97819657
55Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.94671495
56Autoimmune thyroid disease_Homo sapiens_hsa053200.92837434
57Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.91649456
58Pancreatic cancer_Homo sapiens_hsa052120.91050765
59Systemic lupus erythematosus_Homo sapiens_hsa053220.84267502
60Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.81614222
61Prion diseases_Homo sapiens_hsa050200.81153314
62Epstein-Barr virus infection_Homo sapiens_hsa051690.80478127
63Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.80250158
64Neurotrophin signaling pathway_Homo sapiens_hsa047220.78670428
65Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.77248077
66Lysosome_Homo sapiens_hsa041420.76401446
67ABC transporters_Homo sapiens_hsa020100.75414023
68Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.73857435
69Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.73722020
70Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.70122095
71African trypanosomiasis_Homo sapiens_hsa051430.70031896
72Viral myocarditis_Homo sapiens_hsa054160.64407645
73Type II diabetes mellitus_Homo sapiens_hsa049300.64360056
74Collecting duct acid secretion_Homo sapiens_hsa049660.64134995
75Small cell lung cancer_Homo sapiens_hsa052220.62881615
76Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.61318391
77Renin-angiotensin system_Homo sapiens_hsa046140.61212925
78Circadian rhythm_Homo sapiens_hsa047100.61147023
79Complement and coagulation cascades_Homo sapiens_hsa046100.60836205
80Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.60039194
81HTLV-I infection_Homo sapiens_hsa051660.59921756
82Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.59485084
83Bladder cancer_Homo sapiens_hsa052190.59209190
84Carbohydrate digestion and absorption_Homo sapiens_hsa049730.59016973
85Notch signaling pathway_Homo sapiens_hsa043300.52532519
86Viral carcinogenesis_Homo sapiens_hsa052030.52521066
87FoxO signaling pathway_Homo sapiens_hsa040680.52270979
88Vitamin digestion and absorption_Homo sapiens_hsa049770.51802360
89Adipocytokine signaling pathway_Homo sapiens_hsa049200.51176886
90Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.50866969
91Inositol phosphate metabolism_Homo sapiens_hsa005620.50480597
92Mineral absorption_Homo sapiens_hsa049780.46729103
93p53 signaling pathway_Homo sapiens_hsa041150.46037186
94Sphingolipid signaling pathway_Homo sapiens_hsa040710.44877229
95Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.44730146
96Sphingolipid metabolism_Homo sapiens_hsa006000.44593619
97Insulin resistance_Homo sapiens_hsa049310.44039717
98Phagosome_Homo sapiens_hsa041450.43589196
99VEGF signaling pathway_Homo sapiens_hsa043700.42932638
100Colorectal cancer_Homo sapiens_hsa052100.42922112
101Galactose metabolism_Homo sapiens_hsa000520.42843839
102Folate biosynthesis_Homo sapiens_hsa007900.42625669
103Non-small cell lung cancer_Homo sapiens_hsa052230.41602872
104Phosphatidylinositol signaling system_Homo sapiens_hsa040700.41547895
105Fat digestion and absorption_Homo sapiens_hsa049750.40913670
106HIF-1 signaling pathway_Homo sapiens_hsa040660.39237964
107Endocytosis_Homo sapiens_hsa041440.36267266
108Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.35822027
109Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.35161225
110Primary bile acid biosynthesis_Homo sapiens_hsa001200.33363798
111Vibrio cholerae infection_Homo sapiens_hsa051100.29717268
112SNARE interactions in vesicular transport_Homo sapiens_hsa041300.29115579
113Amoebiasis_Homo sapiens_hsa051460.29007769
114MAPK signaling pathway_Homo sapiens_hsa040100.28548412
115Regulation of actin cytoskeleton_Homo sapiens_hsa048100.26295799
116Glutathione metabolism_Homo sapiens_hsa004800.19829142
117Dorso-ventral axis formation_Homo sapiens_hsa043200.15945025
118PPAR signaling pathway_Homo sapiens_hsa033200.12988163
119alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.09990259
120Fructose and mannose metabolism_Homo sapiens_hsa000510.08177279
121Ether lipid metabolism_Homo sapiens_hsa005650.05363680
122Chemical carcinogenesis_Homo sapiens_hsa052040.03327431
123Arachidonic acid metabolism_Homo sapiens_hsa005900.01852292
124Maturity onset diabetes of the young_Homo sapiens_hsa049500.01667336

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