NIM1K

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1behavioral response to nicotine (GO:0035095)4.76056807
2regulation of rhodopsin mediated signaling pathway (GO:0022400)4.49976972
3rhodopsin mediated signaling pathway (GO:0016056)4.43961131
4L-amino acid import (GO:0043092)4.21020301
5neuron cell-cell adhesion (GO:0007158)4.15418008
6presynaptic membrane assembly (GO:0097105)4.13700597
7axon ensheathment in central nervous system (GO:0032291)4.03690650
8central nervous system myelination (GO:0022010)4.03690650
9presynaptic membrane organization (GO:0097090)3.95138419
10amino acid import (GO:0043090)3.89235664
11response to pheromone (GO:0019236)3.87256782
12retinal cone cell development (GO:0046549)3.69330795
13serotonin metabolic process (GO:0042428)3.67414835
14detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.65244158
15neurotransmitter-gated ion channel clustering (GO:0072578)3.64081472
16protein localization to synapse (GO:0035418)3.55185956
17postsynaptic membrane organization (GO:0001941)3.54493961
18DNA methylation involved in gamete generation (GO:0043046)3.50891230
19regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.49469727
20response to auditory stimulus (GO:0010996)3.47658137
21piRNA metabolic process (GO:0034587)3.46229640
22primary amino compound metabolic process (GO:1901160)3.43002428
23neurotransmitter uptake (GO:0001504)3.40768846
24photoreceptor cell maintenance (GO:0045494)3.34940842
25photoreceptor cell development (GO:0042461)3.34417962
26negative regulation of synaptic transmission, GABAergic (GO:0032229)3.33853824
27neuronal action potential propagation (GO:0019227)3.33440247
28photoreceptor cell differentiation (GO:0046530)3.32181572
29eye photoreceptor cell differentiation (GO:0001754)3.32181572
30retinal rod cell development (GO:0046548)3.31976415
31fucose catabolic process (GO:0019317)3.29941895
32L-fucose metabolic process (GO:0042354)3.29941895
33L-fucose catabolic process (GO:0042355)3.29941895
34indolalkylamine metabolic process (GO:0006586)3.29282646
35eye photoreceptor cell development (GO:0042462)3.28456672
36positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.27628564
37transmission of nerve impulse (GO:0019226)3.27021832
38negative regulation of cytosolic calcium ion concentration (GO:0051481)3.25760698
39vocalization behavior (GO:0071625)3.24737400
40glutamate receptor signaling pathway (GO:0007215)3.24683885
41negative regulation of astrocyte differentiation (GO:0048712)3.23828360
42positive regulation of meiosis (GO:0045836)3.20959484
43ionotropic glutamate receptor signaling pathway (GO:0035235)3.17982034
44glutamate secretion (GO:0014047)3.17736406
45gamma-aminobutyric acid transport (GO:0015812)3.17730004
46protein polyglutamylation (GO:0018095)3.14557230
47pyrimidine nucleobase catabolic process (GO:0006208)3.14270174
48regulation of neurotransmitter uptake (GO:0051580)3.13951468
49regulation of respiratory system process (GO:0044065)3.13689336
50regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.13050962
51positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.09905898
52long-term synaptic potentiation (GO:0060291)3.09836771
53G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.09716507
54sphingosine metabolic process (GO:0006670)3.08458255
55auditory behavior (GO:0031223)3.07288688
56cellular potassium ion homeostasis (GO:0030007)3.05975298
57C4-dicarboxylate transport (GO:0015740)3.05780005
58regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.04827435
59indole-containing compound metabolic process (GO:0042430)3.03412045
60locomotory exploration behavior (GO:0035641)3.03199394
61regulation of cilium movement (GO:0003352)3.03081880
62negative regulation of neurotransmitter transport (GO:0051589)3.02558449
63sphingoid metabolic process (GO:0046519)3.00338928
64long-term memory (GO:0007616)3.00336205
65epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.99958673
66neuronal action potential (GO:0019228)2.98730807
67startle response (GO:0001964)2.98577689
68regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.97342239
69positive regulation of meiotic cell cycle (GO:0051446)2.97258089
70synaptic vesicle exocytosis (GO:0016079)2.96287222
71tryptophan catabolic process (GO:0006569)2.95461786
72indole-containing compound catabolic process (GO:0042436)2.95461786
73indolalkylamine catabolic process (GO:0046218)2.95461786
74diol metabolic process (GO:0034311)2.94874779
75axoneme assembly (GO:0035082)2.94735650
76epithelial cilium movement (GO:0003351)2.94048493
77kynurenine metabolic process (GO:0070189)2.93332915
78nucleobase catabolic process (GO:0046113)2.90926177
79serotonin receptor signaling pathway (GO:0007210)2.90194466
80regulation of meiosis I (GO:0060631)2.89859324
81nonmotile primary cilium assembly (GO:0035058)2.89274211
82cellular ketone body metabolic process (GO:0046950)2.88703646
83regulation of short-term neuronal synaptic plasticity (GO:0048172)2.88632772
84oligodendrocyte differentiation (GO:0048709)2.87907079
85detection of light stimulus involved in visual perception (GO:0050908)2.85905945
86detection of light stimulus involved in sensory perception (GO:0050962)2.85905945
87synaptic transmission, glutamatergic (GO:0035249)2.85588406
88regulation of voltage-gated calcium channel activity (GO:1901385)2.83319524
89negative regulation of telomere maintenance (GO:0032205)2.82820292
90regulation of synaptic vesicle exocytosis (GO:2000300)2.80971986
91proline transport (GO:0015824)2.79879828
92fatty acid elongation (GO:0030497)2.78028176
93limb bud formation (GO:0060174)2.77565811
94reflex (GO:0060004)2.76997856
95DNA deamination (GO:0045006)2.76043768
96regulation of synaptic transmission, glutamatergic (GO:0051966)2.75939462
97water-soluble vitamin biosynthetic process (GO:0042364)2.75559737
98regulation of hexokinase activity (GO:1903299)2.73175912
99regulation of glucokinase activity (GO:0033131)2.73175912
100membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.73049548
101glycerophospholipid catabolic process (GO:0046475)2.71957741
102regulation of glutamate receptor signaling pathway (GO:1900449)2.71929329
103neuron-neuron synaptic transmission (GO:0007270)2.71404764
104gamma-aminobutyric acid signaling pathway (GO:0007214)2.71368901
105positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.68234396
106retina layer formation (GO:0010842)2.67481451
107synaptic transmission, cholinergic (GO:0007271)2.67398246
108positive regulation of synapse assembly (GO:0051965)2.65121783
109neuron recognition (GO:0008038)2.65043847
110regulation of respiratory gaseous exchange (GO:0043576)2.64821132
111cerebellar granule cell differentiation (GO:0021707)2.64372667
112negative regulation of protein localization to cell surface (GO:2000009)2.62798289
113negative regulation of peptidyl-threonine phosphorylation (GO:0010801)2.62636804
114phototransduction (GO:0007602)2.61924105
115adaptation of signaling pathway (GO:0023058)2.61863600
116dendritic spine morphogenesis (GO:0060997)2.60457074
117mechanosensory behavior (GO:0007638)2.60383387
118regulation of microtubule-based movement (GO:0060632)2.59967219
119neurotransmitter transport (GO:0006836)2.59775947
120membrane depolarization during action potential (GO:0086010)2.59728551
121regulation of vesicle fusion (GO:0031338)2.58713867
122regulation of timing of cell differentiation (GO:0048505)2.58501721
123potassium ion transmembrane transport (GO:0071805)2.58154072
124cellular potassium ion transport (GO:0071804)2.58154072
125positive regulation of synaptic transmission, GABAergic (GO:0032230)2.58061099
126cerebral cortex radially oriented cell migration (GO:0021799)2.57938638
127negative regulation of neurotransmitter secretion (GO:0046929)2.57873113
128positive regulation of oligodendrocyte differentiation (GO:0048714)2.56397841
129atrial cardiac muscle cell action potential (GO:0086014)2.55261819
130behavioral response to ethanol (GO:0048149)2.55220888
131protein-chromophore linkage (GO:0018298)2.54750728
132regulation of synaptic vesicle transport (GO:1902803)2.54651111
133regulation of neurotransmitter secretion (GO:0046928)2.54253378
134ketone body metabolic process (GO:1902224)2.54081132
135positive regulation of guanylate cyclase activity (GO:0031284)2.52471983
136regulation of neuronal synaptic plasticity (GO:0048168)2.50981666
137phototransduction, visible light (GO:0007603)2.50577912
138detection of light stimulus (GO:0009583)2.50391741
139cilium movement (GO:0003341)2.48573522
140regulation of astrocyte differentiation (GO:0048710)2.48568915
141positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.47982919
142tryptophan metabolic process (GO:0006568)2.47937856
143neurotransmitter secretion (GO:0007269)2.47207675
144detection of visible light (GO:0009584)2.46154759
145lateral sprouting from an epithelium (GO:0060601)2.45760404
146detection of mechanical stimulus involved in sensory perception (GO:0050974)2.45562408
147regulation of excitatory postsynaptic membrane potential (GO:0060079)2.45546027
148cellular biogenic amine catabolic process (GO:0042402)2.45433255
149amine catabolic process (GO:0009310)2.45433255
150regulation of postsynaptic membrane potential (GO:0060078)2.45301115
151cilium morphogenesis (GO:0060271)2.44979233
152learning (GO:0007612)2.44916723
153platelet dense granule organization (GO:0060155)2.44790673
154cAMP catabolic process (GO:0006198)2.44399547
155positive regulation of action potential (GO:0045760)2.43894594
156protein complex biogenesis (GO:0070271)2.43229896
157phasic smooth muscle contraction (GO:0014821)2.42452902
158sulfate transmembrane transport (GO:1902358)2.42335336
159regulation of protein glycosylation (GO:0060049)2.41009306
160ubiquinone biosynthetic process (GO:0006744)2.41006508
161synaptic vesicle maturation (GO:0016188)2.40666187
162auditory receptor cell stereocilium organization (GO:0060088)2.40343316
163potassium ion transport (GO:0006813)2.39953567
164alanine transport (GO:0032328)2.38091216
165visual perception (GO:0007601)2.37076134
166regulation of long-term neuronal synaptic plasticity (GO:0048169)2.36203054
167sensory perception of light stimulus (GO:0050953)2.34960813

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.93649624
2GBX2_23144817_ChIP-Seq_PC3_Human3.73218900
3ZNF274_21170338_ChIP-Seq_K562_Hela3.25692301
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.73902024
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.65679113
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.60449150
7GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.60062025
8AR_21572438_ChIP-Seq_LNCaP_Human2.55799384
9EZH2_27304074_Chip-Seq_ESCs_Mouse2.40618410
10SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.35802191
11SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.34201537
12SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.33663009
13EED_16625203_ChIP-ChIP_MESCs_Mouse2.33047859
14JARID2_20075857_ChIP-Seq_MESCs_Mouse2.27147122
15RNF2_18974828_ChIP-Seq_MESCs_Mouse2.20988270
16EZH2_18974828_ChIP-Seq_MESCs_Mouse2.20988270
17MTF2_20144788_ChIP-Seq_MESCs_Mouse2.12686801
18GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.10463590
19TAF15_26573619_Chip-Seq_HEK293_Human2.09395891
20SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.02360993
21ZFP57_27257070_Chip-Seq_ESCs_Mouse2.00620055
22RNF2_27304074_Chip-Seq_ESCs_Mouse1.98531459
23CBX2_27304074_Chip-Seq_ESCs_Mouse1.90966071
24EZH2_27294783_Chip-Seq_ESCs_Mouse1.88088762
25CTBP2_25329375_ChIP-Seq_LNCAP_Human1.86388515
26SUZ12_27294783_Chip-Seq_ESCs_Mouse1.85875847
27SMAD_19615063_ChIP-ChIP_OVARY_Human1.84386970
28P300_19829295_ChIP-Seq_ESCs_Human1.84060814
29CTBP1_25329375_ChIP-Seq_LNCAP_Human1.79427773
30PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.77319522
31REST_21632747_ChIP-Seq_MESCs_Mouse1.73624275
32PIAS1_25552417_ChIP-Seq_VCAP_Human1.72865363
33SMAD4_21799915_ChIP-Seq_A2780_Human1.71034066
34SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.63646339
35BMI1_23680149_ChIP-Seq_NPCS_Mouse1.62733244
36VDR_22108803_ChIP-Seq_LS180_Human1.59603671
37RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.59233538
38EWS_26573619_Chip-Seq_HEK293_Human1.58393645
39TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.57631848
40DROSHA_22980978_ChIP-Seq_HELA_Human1.56660943
41POU3F2_20337985_ChIP-ChIP_501MEL_Human1.55727455
42SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.53327358
43CDX2_19796622_ChIP-Seq_MESCs_Mouse1.52720962
44PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.52452170
45RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.48422069
46CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.46127938
47SMAD3_21741376_ChIP-Seq_EPCs_Human1.46047728
48FUS_26573619_Chip-Seq_HEK293_Human1.44780992
49TOP2B_26459242_ChIP-Seq_MCF-7_Human1.44438596
50OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.41255343
51HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.40136308
52PCGF2_27294783_Chip-Seq_NPCs_Mouse1.39374020
53CBP_20019798_ChIP-Seq_JUKART_Human1.37921934
54IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.37921934
55MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.37635834
56UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.35570151
57SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.35192794
58RNF2_27304074_Chip-Seq_NSC_Mouse1.34560739
59IKZF1_21737484_ChIP-ChIP_HCT116_Human1.33855327
60AR_25329375_ChIP-Seq_VCAP_Human1.33134966
61ER_23166858_ChIP-Seq_MCF-7_Human1.31136075
62EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.30387892
63NR3C1_21868756_ChIP-Seq_MCF10A_Human1.29843109
64TP53_22573176_ChIP-Seq_HFKS_Human1.29833272
65NANOG_19829295_ChIP-Seq_ESCs_Human1.28016590
66SOX2_19829295_ChIP-Seq_ESCs_Human1.28016590
67STAT3_23295773_ChIP-Seq_U87_Human1.27861634
68SALL1_21062744_ChIP-ChIP_HESCs_Human1.27645997
69TCF4_22108803_ChIP-Seq_LS180_Human1.26546877
70NANOG_18555785_Chip-Seq_ESCs_Mouse1.26389267
71HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.23918328
72NFE2_27457419_Chip-Seq_LIVER_Mouse1.23888516
73TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.23361915
74ZNF217_24962896_ChIP-Seq_MCF-7_Human1.22631465
75AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.22271618
76TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.21941286
77CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.20228875
78RING1B_27294783_Chip-Seq_ESCs_Mouse1.20050241
79FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.20004564
80NR3C1_23031785_ChIP-Seq_PC12_Mouse1.19466923
81SMAD4_21741376_ChIP-Seq_EPCs_Human1.18280141
82REST_18959480_ChIP-ChIP_MESCs_Mouse1.18076605
83ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.17695341
84EZH2_27294783_Chip-Seq_NPCs_Mouse1.17465975
85NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.17393792
86KLF5_20875108_ChIP-Seq_MESCs_Mouse1.17347589
87PRDM14_20953172_ChIP-Seq_ESCs_Human1.17138691
88TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16511443
89MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.16239150
90TP53_18474530_ChIP-ChIP_U2OS_Human1.16092425
91RUNX2_22187159_ChIP-Seq_PCA_Human1.15501215
92FLI1_21867929_ChIP-Seq_TH2_Mouse1.15355660
93IGF1R_20145208_ChIP-Seq_DFB_Human1.15040196
94EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.15021115
95NOTCH1_21737748_ChIP-Seq_TLL_Human1.13936533
96E2F1_18555785_Chip-Seq_ESCs_Mouse1.12258087
97MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.12097772
98GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.11587602
99PCGF2_27294783_Chip-Seq_ESCs_Mouse1.11467309
100BCAT_22108803_ChIP-Seq_LS180_Human1.11356797
101CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.09986166
102POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.08638057
103TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08638057
104FLI1_27457419_Chip-Seq_LIVER_Mouse1.08629640
105KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.08416177
106PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.08300722
107TCF4_23295773_ChIP-Seq_U87_Human1.07708959
108EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.06817235
109LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06774687
110RING1B_27294783_Chip-Seq_NPCs_Mouse1.06200952
111RARB_27405468_Chip-Seq_BRAIN_Mouse1.05951648
112FOXA1_27270436_Chip-Seq_PROSTATE_Human1.05721834
113FOXA1_25329375_ChIP-Seq_VCAP_Human1.05721834
114SUZ12_27294783_Chip-Seq_NPCs_Mouse1.05513964
115SOX2_21211035_ChIP-Seq_LN229_Gbm1.05328818
116P53_22387025_ChIP-Seq_ESCs_Mouse1.03571417
117NCOR_22424771_ChIP-Seq_293T_Human1.03286304
118CMYC_18555785_Chip-Seq_ESCs_Mouse1.02120743
119SUZ12_18555785_Chip-Seq_ESCs_Mouse1.01790395
120TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.01735292
121CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.01514869
122EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.00182514
123ARNT_22903824_ChIP-Seq_MCF-7_Human0.99253137
124TP53_16413492_ChIP-PET_HCT116_Human0.98511247
125AHR_22903824_ChIP-Seq_MCF-7_Human0.98167658
126STAT3_18555785_Chip-Seq_ESCs_Mouse0.98109317
127NRF2_20460467_ChIP-Seq_MEFs_Mouse0.97756379
128NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.97756379
129JUN_21703547_ChIP-Seq_K562_Human0.97522115
130P53_22127205_ChIP-Seq_FIBROBLAST_Human0.97179227
131P300_18555785_Chip-Seq_ESCs_Mouse0.95322770

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern3.76080520
2MP0005551_abnormal_eye_electrophysiolog3.69043996
3MP0002837_dystrophic_cardiac_calcinosis3.47130374
4MP0003136_yellow_coat_color3.06515287
5MP0005646_abnormal_pituitary_gland3.03045753
6MP0004270_analgesia2.94012692
7MP0005423_abnormal_somatic_nervous2.89529205
8MP0004859_abnormal_synaptic_plasticity2.84083926
9MP0002653_abnormal_ependyma_morphology2.81409548
10MP0003011_delayed_dark_adaptation2.77015647
11MP0002638_abnormal_pupillary_reflex2.55065246
12MP0009745_abnormal_behavioral_response2.54756717
13MP0005253_abnormal_eye_physiology2.54309703
14MP0003635_abnormal_synaptic_transmissio2.52397591
15MP0006072_abnormal_retinal_apoptosis2.49763324
16MP0003690_abnormal_glial_cell2.49557633
17MP0008877_abnormal_DNA_methylation2.45199496
18MP0001486_abnormal_startle_reflex2.38621353
19MP0003195_calcinosis2.31689996
20MP0002734_abnormal_mechanical_nocicepti2.29395895
21MP0002064_seizures2.28555968
22MP0001968_abnormal_touch/_nociception2.27737721
23MP0002736_abnormal_nociception_after2.21328813
24MP0002063_abnormal_learning/memory/cond2.13651761
25MP0000569_abnormal_digit_pigmentation2.13549971
26MP0003787_abnormal_imprinting2.13029522
27MP0002272_abnormal_nervous_system2.10829719
28MP0009046_muscle_twitch2.07176690
29MP0002572_abnormal_emotion/affect_behav2.03114757
30MP0005645_abnormal_hypothalamus_physiol2.00486019
31MP0001501_abnormal_sleep_pattern1.95666295
32MP0009780_abnormal_chondrocyte_physiolo1.89665691
33MP0002735_abnormal_chemical_nociception1.87535800
34MP0003646_muscle_fatigue1.84564722
35MP0004147_increased_porphyrin_level1.81965810
36MP0006292_abnormal_olfactory_placode1.81162776
37MP0002090_abnormal_vision1.80091091
38MP0001502_abnormal_circadian_rhythm1.77157140
39MP0002102_abnormal_ear_morphology1.75720586
40MP0001440_abnormal_grooming_behavior1.74410038
41MP0000778_abnormal_nervous_system1.73186656
42MP0004885_abnormal_endolymph1.72035907
43MP0001984_abnormal_olfaction1.70102190
44MP0003950_abnormal_plasma_membrane1.65529030
45MP0003283_abnormal_digestive_organ1.63075345
46MP0004858_abnormal_nervous_system1.58755656
47MP0002067_abnormal_sensory_capabilities1.58059277
48MP0004043_abnormal_pH_regulation1.55024578
49MP0001970_abnormal_pain_threshold1.53063371
50MP0002733_abnormal_thermal_nociception1.52076332
51MP0005195_abnormal_posterior_eye1.50470915
52MP0001986_abnormal_taste_sensitivity1.48799318
53MP0002254_reproductive_system_inflammat1.47618330
54MP0001905_abnormal_dopamine_level1.46954300
55MP0002938_white_spotting1.43678652
56MP0002557_abnormal_social/conspecific_i1.41465107
57MP0006276_abnormal_autonomic_nervous1.41447448
58MP0005171_absent_coat_pigmentation1.39033109
59MP0002882_abnormal_neuron_morphology1.37329475
60MP0003329_amyloid_beta_deposits1.36977125
61MP0002928_abnormal_bile_duct1.36641906
62MP0003890_abnormal_embryonic-extraembry1.36050741
63MP0004142_abnormal_muscle_tone1.34525835
64MP0003634_abnormal_glial_cell1.34190261
65MP0005409_darkened_coat_color1.33894324
66MP0003879_abnormal_hair_cell1.33001354
67MP0002229_neurodegeneration1.32994895
68MP0001529_abnormal_vocalization1.31190081
69MP0001188_hyperpigmentation1.30737116
70MP0000427_abnormal_hair_cycle1.30682031
71MP0001963_abnormal_hearing_physiology1.27957006
72MP0002752_abnormal_somatic_nervous1.27015471
73MP0004742_abnormal_vestibular_system1.26843428
74MP0000920_abnormal_myelination1.26508536
75MP0002822_catalepsy1.26265985
76MP0002876_abnormal_thyroid_physiology1.25091286
77MP0005386_behavior/neurological_phenoty1.22099122
78MP0004924_abnormal_behavior1.22099122
79MP0000631_abnormal_neuroendocrine_gland1.21353012
80MP0005379_endocrine/exocrine_gland_phen1.17415306
81MP0003122_maternal_imprinting1.13682269
82MP0000026_abnormal_inner_ear1.13319801
83MP0008569_lethality_at_weaning1.12308035
84MP0008875_abnormal_xenobiotic_pharmacok1.11568552
85MP0002184_abnormal_innervation1.11316546
86MP0003633_abnormal_nervous_system1.09867663
87MP0005391_vision/eye_phenotype1.09415998
88MP0004133_heterotaxia1.08345503
89MP0002909_abnormal_adrenal_gland1.06995229
90MP0003075_altered_response_to1.06743731
91MP0003045_fibrosis1.04883512
92MP0005085_abnormal_gallbladder_physiolo1.03566779
93MP0005174_abnormal_tail_pigmentation0.99113312
94MP0005499_abnormal_olfactory_system0.98710769
95MP0005394_taste/olfaction_phenotype0.98710769
96MP0004134_abnormal_chest_morphology0.97849960
97MP0005075_abnormal_melanosome_morpholog0.97380774
98MP0001485_abnormal_pinna_reflex0.97179947
99MP0000566_synostosis0.96685563
100MP0003183_abnormal_peptide_metabolism0.96109333
101MP0000372_irregular_coat_pigmentation0.95585608
102MP0002160_abnormal_reproductive_system0.95495443
103MP0000955_abnormal_spinal_cord0.93823902
104MP0003631_nervous_system_phenotype0.93620003
105MP0002066_abnormal_motor_capabilities/c0.93334001
106MP0008872_abnormal_physiological_respon0.91807310
107MP0001324_abnormal_eye_pigmentation0.91800344
108MP0005084_abnormal_gallbladder_morpholo0.91421871
109MP0002095_abnormal_skin_pigmentation0.89563717
110MP0003121_genomic_imprinting0.88444038
111MP0002163_abnormal_gland_morphology0.87131404
112MP0000049_abnormal_middle_ear0.86733580
113MP0010386_abnormal_urinary_bladder0.84684953
114MP0003938_abnormal_ear_development0.84533021
115MP0005377_hearing/vestibular/ear_phenot0.83815025
116MP0003878_abnormal_ear_physiology0.83815025
117MP0009250_abnormal_appendicular_skeleto0.82368030
118MP0008789_abnormal_olfactory_epithelium0.81035630
119MP0003632_abnormal_nervous_system0.80878394
120MP0002751_abnormal_autonomic_nervous0.80597120
121MP0009384_cardiac_valve_regurgitation0.80465125
122MP0002132_abnormal_respiratory_system0.76758398
123MP0003137_abnormal_impulse_conducting0.76547584
124MP0005389_reproductive_system_phenotype0.75349259
125MP0002152_abnormal_brain_morphology0.73401838
126MP0003698_abnormal_male_reproductive0.69864769
127MP0000230_abnormal_systemic_arterial0.69617144
128MP0001177_atelectasis0.65207085
129MP0005595_abnormal_vascular_smooth0.65019220
130MP0000604_amyloidosis0.63896476
131MP0004085_abnormal_heartbeat0.62732713
132MP0002295_abnormal_pulmonary_circulatio0.62499442
133MP0004883_abnormal_blood_vessel0.60284293
134MP0005410_abnormal_fertilization0.57581098
135MP0001346_abnormal_lacrimal_gland0.56618810
136MP0005248_abnormal_Harderian_gland0.56507655

Predicted human phenotypes

RankGene SetZ-score
1Congenital stationary night blindness (HP:0007642)5.30398779
2Aplasia involving bones of the upper limbs (HP:0009823)4.99750551
3Aplasia of the phalanges of the hand (HP:0009802)4.99750551
4Aplasia involving bones of the extremities (HP:0009825)4.99750551
5Pancreatic cysts (HP:0001737)4.28421794
6Focal motor seizures (HP:0011153)4.27217024
7Bony spicule pigmentary retinopathy (HP:0007737)4.23790944
8Epileptic encephalopathy (HP:0200134)4.11250920
9Chorioretinal atrophy (HP:0000533)3.63004870
10Hyperventilation (HP:0002883)3.60874582
11Abnormality of midbrain morphology (HP:0002418)3.47856848
12Molar tooth sign on MRI (HP:0002419)3.47856848
13Nephronophthisis (HP:0000090)3.46552795
14Decreased central vision (HP:0007663)3.30226787
15Abnormal ciliary motility (HP:0012262)3.28630501
16Dyschromatopsia (HP:0007641)3.28583928
17Pigmentary retinal degeneration (HP:0001146)3.27188484
18Abnormal rod and cone electroretinograms (HP:0008323)3.20718719
19Type II lissencephaly (HP:0007260)3.14543441
20Abnormality of the renal cortex (HP:0011035)3.09071781
21Abnormality of the renal medulla (HP:0100957)3.08388931
22Central scotoma (HP:0000603)3.05381448
23Abnormality of macular pigmentation (HP:0008002)3.04790830
24Neurofibrillary tangles (HP:0002185)3.04032310
25Attenuation of retinal blood vessels (HP:0007843)3.01240891
26Myokymia (HP:0002411)2.92607502
27Hemiparesis (HP:0001269)2.92084004
28Progressive cerebellar ataxia (HP:0002073)2.90278638
29Medial flaring of the eyebrow (HP:0010747)2.87791936
30Scotoma (HP:0000575)2.84294811
31Absent rod-and cone-mediated responses on ERG (HP:0007688)2.82965375
32Increased corneal curvature (HP:0100692)2.82961150
33Keratoconus (HP:0000563)2.82961150
34Abolished electroretinogram (ERG) (HP:0000550)2.81850981
35Focal seizures (HP:0007359)2.77669199
36Megalencephaly (HP:0001355)2.76544305
37Febrile seizures (HP:0002373)2.75702364
38Gait imbalance (HP:0002141)2.74681791
39Confusion (HP:0001289)2.74379200
40Abnormal respiratory motile cilium physiology (HP:0012261)2.73886627
41Dynein arm defect of respiratory motile cilia (HP:0012255)2.70952316
42Absent/shortened dynein arms (HP:0200106)2.70952316
43Gaze-evoked nystagmus (HP:0000640)2.66171806
44Congenital primary aphakia (HP:0007707)2.63759140
45Inability to walk (HP:0002540)2.61466903
46Pendular nystagmus (HP:0012043)2.59946321
47Progressive inability to walk (HP:0002505)2.55524397
48Retinitis pigmentosa (HP:0000510)2.53854592
49Mixed hearing impairment (HP:0000410)2.53145996
50Diplopia (HP:0000651)2.52971509
51Abnormality of binocular vision (HP:0011514)2.52971509
52Clumsiness (HP:0002312)2.52879317
53Nephrogenic diabetes insipidus (HP:0009806)2.50514327
54Cystic liver disease (HP:0006706)2.48053832
55Amelogenesis imperfecta (HP:0000705)2.47706038
56Large for gestational age (HP:0001520)2.47483858
57Abnormal drinking behavior (HP:0030082)2.46475921
58Polydipsia (HP:0001959)2.46475921
59Tubular atrophy (HP:0000092)2.45468718
60Atonic seizures (HP:0010819)2.41799676
61Degeneration of the lateral corticospinal tracts (HP:0002314)2.37837114
62Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.37837114
63Chronic hepatic failure (HP:0100626)2.33294570
64Lissencephaly (HP:0001339)2.31897550
65Hypoplastic left heart (HP:0004383)2.29341031
66Abnormal respiratory epithelium morphology (HP:0012253)2.27953225
67Abnormal respiratory motile cilium morphology (HP:0005938)2.27953225
68Photophobia (HP:0000613)2.26170092
69Synostosis involving the elbow (HP:0003938)2.25570715
70Humeroradial synostosis (HP:0003041)2.25570715
71True hermaphroditism (HP:0010459)2.23624867
72Retinal atrophy (HP:0001105)2.23557911
73Hypoplasia of the fovea (HP:0007750)2.22790056
74Aplasia/Hypoplasia of the fovea (HP:0008060)2.22790056
75Abnormality of incisor morphology (HP:0011063)2.22577761
76Generalized tonic-clonic seizures (HP:0002069)2.21634520
77Limb dystonia (HP:0002451)2.20420888
78Dysdiadochokinesis (HP:0002075)2.19068770
79Macular degeneration (HP:0000608)2.18420430
80Abnormality of the fovea (HP:0000493)2.18302779
81Broad-based gait (HP:0002136)2.17124965
82Sclerocornea (HP:0000647)2.16410129
83Absent speech (HP:0001344)2.16268817
84Cerebellar dysplasia (HP:0007033)2.16234530
85Ulnar claw (HP:0001178)2.12253218
86Choroideremia (HP:0001139)2.11082221
87Abnormality of the labia minora (HP:0012880)2.10622416
88Alacrima (HP:0000522)2.09346212
89Nasolacrimal duct obstruction (HP:0000579)2.07687401
90Polyphagia (HP:0002591)2.06732890
91Optic nerve hypoplasia (HP:0000609)2.05720065
92Cone-rod dystrophy (HP:0000548)2.05175904
93Abnormality of secondary sexual hair (HP:0009888)2.03532674
94Abnormality of the axillary hair (HP:0100134)2.03532674
95Vaginal atresia (HP:0000148)2.03207762
96Genetic anticipation (HP:0003743)2.01898974
97Genital tract atresia (HP:0001827)2.01160613
98Vitreoretinal degeneration (HP:0000655)2.00937610
99Cerebral inclusion bodies (HP:0100314)2.00826965
100Dialeptic seizures (HP:0011146)2.00821446
101Blue irides (HP:0000635)1.99273189
102Abnormality of the dental pulp (HP:0006479)1.99268630
103Retinal dysplasia (HP:0007973)1.99173178
104Pachygyria (HP:0001302)1.98807614
105Cupped ear (HP:0000378)1.98622016
106Renal cortical cysts (HP:0000803)1.96682940
107Optic disc pallor (HP:0000543)1.96061206
108Congenital hepatic fibrosis (HP:0002612)1.95995750
109Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.94063367
110Acute necrotizing encephalopathy (HP:0006965)1.93543404
111Polyuria (HP:0000103)1.93520347
112Aplasia/Hypoplasia of the tibia (HP:0005772)1.93065673
113Severe muscular hypotonia (HP:0006829)1.92855954
114Abnormality of permanent molar morphology (HP:0011071)1.92759970
115Abnormality of the dental root (HP:0006486)1.92759970
116Taurodontia (HP:0000679)1.92759970
117Anencephaly (HP:0002323)1.91295190
118Progressive macrocephaly (HP:0004481)1.91285671
119Supranuclear gaze palsy (HP:0000605)1.90929172
120Methylmalonic acidemia (HP:0002912)1.89104671
121Abnormality of alanine metabolism (HP:0010916)1.88264762
122Hyperalaninemia (HP:0003348)1.88264762
123Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.88264762
124Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.87991962
125Fibular aplasia (HP:0002990)1.87852836
126Pancreatic fibrosis (HP:0100732)1.87740445
127Agitation (HP:0000713)1.86748145
128Tubulointerstitial nephritis (HP:0001970)1.86677432
129Type II diabetes mellitus (HP:0005978)1.86494116
130Congenital sensorineural hearing impairment (HP:0008527)1.86052694
131Hypothermia (HP:0002045)1.85909782
132Mitochondrial inheritance (HP:0001427)1.85822435
133Aplasia/Hypoplasia of the tongue (HP:0010295)1.85641449
134Dysmetria (HP:0001310)1.84752362
135Absence seizures (HP:0002121)1.84241991
136Poor coordination (HP:0002370)1.84034366
137Abnormality of molar (HP:0011077)1.84000240
138Abnormality of molar morphology (HP:0011070)1.84000240
139Aplasia/Hypoplasia of the lens (HP:0008063)1.83241087
140Hypoplastic heart (HP:0001961)1.82028005
141Thickened helices (HP:0000391)1.81494486
142Protruding tongue (HP:0010808)1.79866258
143Split foot (HP:0001839)1.79365426
144Drooling (HP:0002307)1.78464565
145Concave nail (HP:0001598)1.78454593
146Specific learning disability (HP:0001328)1.78243061
147Increased CSF lactate (HP:0002490)1.77998335
148Decreased electroretinogram (ERG) amplitude (HP:0000654)1.77444705
149Furrowed tongue (HP:0000221)1.76938921
150Ketoacidosis (HP:0001993)1.76672752
151Abnormal eating behavior (HP:0100738)1.76292067
152Colon cancer (HP:0003003)1.76031225
153Epileptiform EEG discharges (HP:0011182)1.72943618
154Stomach cancer (HP:0012126)1.72199465
155Aplasia/Hypoplasia of the uvula (HP:0010293)1.71420344
156Intestinal atresia (HP:0011100)1.70178144
157Acute encephalopathy (HP:0006846)1.70169157

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK5.35033733
2FRK5.20257473
3EPHA43.55091558
4TNIK2.83166362
5MAP2K72.72648122
6NTRK32.63459054
7LATS12.61167165
8MAP4K22.56645164
9ACVR1B2.50944485
10MAP3K42.28124504
11ZAK2.25375849
12AKT32.18554945
13PBK2.13453006
14GRK12.04685620
15NTRK22.03406513
16NEK61.89212201
17MAPK131.78704588
18MAP3K121.68599204
19TRIM281.65342988
20MAP2K41.61629470
21BMPR21.60454157
22SGK4941.60282550
23SGK2231.60282550
24MUSK1.56920123
25SGK21.56478631
26MARK11.53986744
27TAOK31.52301630
28WNK41.51743898
29NUAK11.50378403
30PHKG11.43199721
31PHKG21.43199721
32MAPK151.38800067
33PINK11.33557141
34CDK31.33222173
35PRKD31.31588978
36OXSR11.30419992
37STK391.26783030
38GRK71.26617374
39INSRR1.22744385
40MAP3K61.22270070
41PRPF4B1.18375149
42MINK11.16814724
43MAPK71.16747196
44PNCK1.15946384
45BCR1.14555789
46ERBB41.13715061
47PLK21.11666386
48FES1.11014881
49RIPK41.11007289
50LMTK21.09746256
51PRKCE1.08841014
52NLK1.07929707
53PIK3CA1.05759906
54TLK11.05101500
55FGR1.03998909
56LATS21.02637334
57TNK20.99449899
58BCKDK0.99247695
59ADRBK20.97390151
60TIE10.96071001
61MAPK120.95865270
62CDK50.95681598
63PKN10.93919572
64PRKCG0.92253163
65SGK30.91991387
66CAMK2A0.91257440
67ADRBK10.90562960
68GRK50.88783635
69DYRK20.88723964
70TXK0.88094628
71FGFR20.87448002
72MAP2K20.84421895
73BMPR1B0.83669758
74DYRK1A0.81703294
75PAK60.81632785
76CSNK1A1L0.79650113
77SIK20.79087870
78CAMK2D0.78128776
79TSSK60.77231969
80MKNK20.75283922
81CSNK1G30.73265605
82CAMK2B0.73176072
83STK380.72836547
84CSNK1G10.69720137
85PDK20.68076777
86NTRK10.67262918
87IRAK20.66787556
88SGK10.66653248
89MAPKAPK50.63994626
90PAK30.61969040
91CAMK1G0.61705881
92CAMK2G0.60934908
93IRAK10.59246957
94STK160.59161694
95PRKCQ0.58971785
96ROCK20.57350892
97VRK10.56926545
98PRKCH0.56329924
99DAPK20.54869675
100NEK20.53520997
101UHMK10.53321491
102ERBB30.51151399
103PTK2B0.50440360
104PRKACA0.49284597
105IRAK30.48876012
106PRKCI0.48839265
107MAP2K60.48664453
108STK110.48295527
109YES10.48264254
110EPHA30.47210598
111CDC42BPA0.46959469
112TGFBR10.46307605
113CAMK10.45989128
114STK38L0.45984991
115CAMKK20.45771968
116STK30.45412784
117PRKG10.45104758
118MAP3K140.44598701
119PRKCA0.44561239
120CAMKK10.44217086
121PRKD20.43412079
122PRKCZ0.43276486
123CSNK1A10.42615828
124PIK3CG0.41876575
125CDK80.41704286
126WNK30.41625913
127CSNK1G20.40791046
128EPHB20.40514574
129PRKAA20.40457632
130RET0.39592916
131CAMK1D0.38844354
132CSNK1D0.38769603
133HIPK20.37348988
134NME10.37220944
135PLK30.35950552
136ROCK10.35169378
137RPS6KA50.35102211
138SIK30.35068822
139RPS6KA30.33333768
140MST40.31578887
141MAPK40.31264591

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047446.01128384
2Nicotine addiction_Homo sapiens_hsa050332.96771248
3Nitrogen metabolism_Homo sapiens_hsa009102.91957320
4Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.67551407
5Maturity onset diabetes of the young_Homo sapiens_hsa049502.59300738
6GABAergic synapse_Homo sapiens_hsa047272.45295901
7Glutamatergic synapse_Homo sapiens_hsa047242.38164337
8Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.27290980
9Morphine addiction_Homo sapiens_hsa050322.15251297
10Circadian entrainment_Homo sapiens_hsa047132.04367003
11Synaptic vesicle cycle_Homo sapiens_hsa047211.97974208
12Olfactory transduction_Homo sapiens_hsa047401.85736628
13Serotonergic synapse_Homo sapiens_hsa047261.79151717
14Salivary secretion_Homo sapiens_hsa049701.78516979
15Amphetamine addiction_Homo sapiens_hsa050311.70947921
16Insulin secretion_Homo sapiens_hsa049111.70819222
17Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.69235456
18Tryptophan metabolism_Homo sapiens_hsa003801.67833219
19Cocaine addiction_Homo sapiens_hsa050301.60938779
20Fatty acid biosynthesis_Homo sapiens_hsa000611.59921809
21Protein export_Homo sapiens_hsa030601.52656951
22Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.48400651
23Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.47845225
24Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.47498859
25Dopaminergic synapse_Homo sapiens_hsa047281.44466948
26Renin secretion_Homo sapiens_hsa049241.42465055
27Selenocompound metabolism_Homo sapiens_hsa004501.42376582
28Cholinergic synapse_Homo sapiens_hsa047251.41897551
29Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.41613774
30Gastric acid secretion_Homo sapiens_hsa049711.38080374
31Steroid biosynthesis_Homo sapiens_hsa001001.37423467
32Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.35916250
33Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.27654408
34Taste transduction_Homo sapiens_hsa047421.26016020
35Long-term potentiation_Homo sapiens_hsa047201.25174105
36Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.25064932
37Fatty acid elongation_Homo sapiens_hsa000621.23522936
38Long-term depression_Homo sapiens_hsa047301.19655649
39Collecting duct acid secretion_Homo sapiens_hsa049661.18784897
40Calcium signaling pathway_Homo sapiens_hsa040201.18644618
41Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.18465751
42Propanoate metabolism_Homo sapiens_hsa006401.15807469
43Ether lipid metabolism_Homo sapiens_hsa005651.15754801
44cAMP signaling pathway_Homo sapiens_hsa040241.14375843
45Circadian rhythm_Homo sapiens_hsa047101.14239632
46Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.10874353
47Primary bile acid biosynthesis_Homo sapiens_hsa001201.10408291
48Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.05410410
49Peroxisome_Homo sapiens_hsa041461.04243037
50Oxidative phosphorylation_Homo sapiens_hsa001901.03381238
51Aldosterone synthesis and secretion_Homo sapiens_hsa049251.01891802
52ABC transporters_Homo sapiens_hsa020101.00954159
53Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.00206671
54Axon guidance_Homo sapiens_hsa043600.96119808
55Caffeine metabolism_Homo sapiens_hsa002320.92719944
56Rheumatoid arthritis_Homo sapiens_hsa053230.91007182
57RNA polymerase_Homo sapiens_hsa030200.89743135
58Basal transcription factors_Homo sapiens_hsa030220.89297453
59Fanconi anemia pathway_Homo sapiens_hsa034600.88302948
60Cardiac muscle contraction_Homo sapiens_hsa042600.88281813
61Oxytocin signaling pathway_Homo sapiens_hsa049210.87829139
62Melanogenesis_Homo sapiens_hsa049160.87813304
63Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.86994898
64Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.86670610
65African trypanosomiasis_Homo sapiens_hsa051430.86158088
66Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.85094831
67Sulfur metabolism_Homo sapiens_hsa009200.81608565
68Homologous recombination_Homo sapiens_hsa034400.79777760
69Mineral absorption_Homo sapiens_hsa049780.78052903
70Steroid hormone biosynthesis_Homo sapiens_hsa001400.77202009
71beta-Alanine metabolism_Homo sapiens_hsa004100.76502116
72Dorso-ventral axis formation_Homo sapiens_hsa043200.76140447
73cGMP-PKG signaling pathway_Homo sapiens_hsa040220.75524190
74Vascular smooth muscle contraction_Homo sapiens_hsa042700.73243987
75Pancreatic secretion_Homo sapiens_hsa049720.72382966
76Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.72080512
77Vitamin digestion and absorption_Homo sapiens_hsa049770.71820530
78Sphingolipid metabolism_Homo sapiens_hsa006000.71704260
79Chemical carcinogenesis_Homo sapiens_hsa052040.70750454
80Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.68254504
81Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.67282482
82GnRH signaling pathway_Homo sapiens_hsa049120.65151986
83Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.64959166
84Alzheimers disease_Homo sapiens_hsa050100.64795076
85Fatty acid metabolism_Homo sapiens_hsa012120.64699299
86Type I diabetes mellitus_Homo sapiens_hsa049400.62199508
87Retinol metabolism_Homo sapiens_hsa008300.61953953
88Regulation of autophagy_Homo sapiens_hsa041400.61811790
89Gap junction_Homo sapiens_hsa045400.61603802
90Phosphatidylinositol signaling system_Homo sapiens_hsa040700.60739806
91Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.60206654
92Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.59936079
93Arachidonic acid metabolism_Homo sapiens_hsa005900.59259002
94Glycerolipid metabolism_Homo sapiens_hsa005610.59165085
95Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.57499091
96Choline metabolism in cancer_Homo sapiens_hsa052310.57235682
97Thyroid hormone synthesis_Homo sapiens_hsa049180.55169216
98Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.55052206
99Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.54918237
100Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.54680105
101SNARE interactions in vesicular transport_Homo sapiens_hsa041300.54241393
102Ras signaling pathway_Homo sapiens_hsa040140.53879150
103Parkinsons disease_Homo sapiens_hsa050120.52437377
104Bile secretion_Homo sapiens_hsa049760.51207856
105Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.50360226
106Vibrio cholerae infection_Homo sapiens_hsa051100.50342837
107ErbB signaling pathway_Homo sapiens_hsa040120.49528386
108Folate biosynthesis_Homo sapiens_hsa007900.49170408
109Metabolic pathways_Homo sapiens_hsa011000.48868467
110Butanoate metabolism_Homo sapiens_hsa006500.48353419
111Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.45719544
112Phospholipase D signaling pathway_Homo sapiens_hsa040720.45707460
113Sphingolipid signaling pathway_Homo sapiens_hsa040710.45429982
114MAPK signaling pathway_Homo sapiens_hsa040100.45277775
115Glycerophospholipid metabolism_Homo sapiens_hsa005640.45030706
116alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.43888639
117Ovarian steroidogenesis_Homo sapiens_hsa049130.43727137
118RNA degradation_Homo sapiens_hsa030180.43456627
119One carbon pool by folate_Homo sapiens_hsa006700.42043379
120Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.40944052
121Purine metabolism_Homo sapiens_hsa002300.40521925
122Huntingtons disease_Homo sapiens_hsa050160.40333191
123Estrogen signaling pathway_Homo sapiens_hsa049150.38597126
124Wnt signaling pathway_Homo sapiens_hsa043100.37170328
125Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.37112596
126Dilated cardiomyopathy_Homo sapiens_hsa054140.37057920
127Autoimmune thyroid disease_Homo sapiens_hsa053200.37051593
128Arginine and proline metabolism_Homo sapiens_hsa003300.35940623
129Hedgehog signaling pathway_Homo sapiens_hsa043400.35237098
130Melanoma_Homo sapiens_hsa052180.34529717
131Cysteine and methionine metabolism_Homo sapiens_hsa002700.34205093
132Fatty acid degradation_Homo sapiens_hsa000710.31229169
133Rap1 signaling pathway_Homo sapiens_hsa040150.28225190
134Histidine metabolism_Homo sapiens_hsa003400.27652046
135Prion diseases_Homo sapiens_hsa050200.27384361
136Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.27139522
137Linoleic acid metabolism_Homo sapiens_hsa005910.26721617
138Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.25600063

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