NKAIN2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a transmembrane protein that interacts with the beta subunit of a sodium/potassium-transporting ATPase. A chromosomal translocation involving this gene is a cause of lymphoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of action potential (GO:0045760)9.05955977
2tachykinin receptor signaling pathway (GO:0007217)8.84502453
3axon ensheathment in central nervous system (GO:0032291)8.12212232
4central nervous system myelination (GO:0022010)8.12212232
5negative regulation of heart rate (GO:0010459)6.80018585
6positive regulation of synaptic transmission, GABAergic (GO:0032230)6.72029156
7positive regulation of digestive system process (GO:0060456)6.52331895
8regulation of glucocorticoid secretion (GO:2000849)6.45775978
9regulation of action potential (GO:0098900)5.43132616
10regulation of corticosteroid hormone secretion (GO:2000846)5.28146246
11positive regulation of steroid hormone secretion (GO:2000833)5.20502256
12pyrimidine nucleobase catabolic process (GO:0006208)5.09015365
13fatty acid elongation (GO:0030497)4.96523036
14postsynaptic membrane organization (GO:0001941)4.87726700
15ensheathment of neurons (GO:0007272)4.83265234
16axon ensheathment (GO:0008366)4.83265234
17myelination (GO:0042552)4.83238416
18long-chain fatty acid biosynthetic process (GO:0042759)4.60832876
19acidic amino acid transport (GO:0015800)4.55607657
20neuron cell-cell adhesion (GO:0007158)4.51302209
21negative regulation of neurotransmitter transport (GO:0051589)4.51173431
22regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.39471221
23L-glutamate transport (GO:0015813)4.35946772
24synaptic vesicle docking involved in exocytosis (GO:0016081)4.34799095
25L-amino acid import (GO:0043092)4.31150096
26synaptic vesicle maturation (GO:0016188)4.28229559
27negative regulation of neurotransmitter secretion (GO:0046929)4.26655782
28nucleobase catabolic process (GO:0046113)4.21568720
29regulation of synaptic transmission, GABAergic (GO:0032228)4.18226494
30neurotransmitter-gated ion channel clustering (GO:0072578)4.17456759
31presynaptic membrane organization (GO:0097090)4.16078314
32establishment of mitochondrion localization (GO:0051654)4.14361917
33startle response (GO:0001964)4.14164896
34neuronal action potential propagation (GO:0019227)4.13232215
35negative regulation of heart contraction (GO:0045822)4.06512640
36positive regulation of renal sodium excretion (GO:0035815)4.00290372
37presynaptic membrane assembly (GO:0097105)3.99634296
38positive regulation of vesicle fusion (GO:0031340)3.96138889
39regulation of short-term neuronal synaptic plasticity (GO:0048172)3.95868189
40positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.88808578
41positive regulation of dendritic spine morphogenesis (GO:0061003)3.86017109
42dendritic spine morphogenesis (GO:0060997)3.85336683
43synaptic vesicle exocytosis (GO:0016079)3.77643241
44neuron recognition (GO:0008038)3.65906455
45positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.65333403
46regulation of steroid hormone secretion (GO:2000831)3.64917213
47myelin maintenance (GO:0043217)3.64652268
48transmission of nerve impulse (GO:0019226)3.64621688
49glutamate secretion (GO:0014047)3.63910460
50regulation of synaptic vesicle exocytosis (GO:2000300)3.61278322
51ionotropic glutamate receptor signaling pathway (GO:0035235)3.60946070
52regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.57224525
53locomotory exploration behavior (GO:0035641)3.56168000
54protein localization to synapse (GO:0035418)3.51085729
55adult walking behavior (GO:0007628)3.47051504
56vocalization behavior (GO:0071625)3.44319531
57regulation of synaptic transmission, glutamatergic (GO:0051966)3.44182462
58response to morphine (GO:0043278)3.39617862
59regulation of vesicle fusion (GO:0031338)3.39175622
60neurotransmitter transport (GO:0006836)3.38099387
61regulation of neuronal synaptic plasticity (GO:0048168)3.37913048
62negative regulation of protein localization to cell surface (GO:2000009)3.34965204
63axonal fasciculation (GO:0007413)3.34491834
64positive regulation of synapse maturation (GO:0090129)3.32759209
65negative regulation of peptidyl-threonine phosphorylation (GO:0010801)3.30825544
66apical protein localization (GO:0045176)3.29653703
67response to isoquinoline alkaloid (GO:0014072)3.29629153
68righting reflex (GO:0060013)3.28699592
69central nervous system projection neuron axonogenesis (GO:0021952)3.28659851
70sodium ion export (GO:0071436)3.26641775
71glutamate receptor signaling pathway (GO:0007215)3.22609395
72regulation of long-term neuronal synaptic plasticity (GO:0048169)3.22509792
73nerve growth factor signaling pathway (GO:0038180)3.22443365
74neuron-neuron synaptic transmission (GO:0007270)3.20778476
75glycerophospholipid catabolic process (GO:0046475)3.18964671
76synaptic transmission, glutamatergic (GO:0035249)3.17715524
77regulation of collateral sprouting (GO:0048670)3.17229505
78amino acid import (GO:0043090)3.16754956
79response to methylmercury (GO:0051597)3.16427388
80negative regulation of synaptic transmission, GABAergic (GO:0032229)3.16212912
81cerebral cortex radially oriented cell migration (GO:0021799)3.14469408
82gamma-aminobutyric acid signaling pathway (GO:0007214)3.13739026
83dendrite morphogenesis (GO:0048813)3.12331077
84neuronal ion channel clustering (GO:0045161)3.11620798
85layer formation in cerebral cortex (GO:0021819)3.11458476
86regulation of glutamate receptor signaling pathway (GO:1900449)3.07761059
87oligodendrocyte differentiation (GO:0048709)3.07325159
88negative regulation of blood circulation (GO:1903523)3.07103156
89C4-dicarboxylate transport (GO:0015740)3.06777325
90membrane assembly (GO:0071709)3.05697647
91asymmetric protein localization (GO:0008105)3.05669103
92regulation of dendritic spine morphogenesis (GO:0061001)3.04722058
93regulation of synaptic vesicle transport (GO:1902803)3.04489433
94negative regulation of axonogenesis (GO:0050771)3.01893299
95membrane depolarization during action potential (GO:0086010)3.01724732
96gamma-aminobutyric acid transport (GO:0015812)3.01525856
97eye photoreceptor cell differentiation (GO:0001754)2.99201585
98photoreceptor cell differentiation (GO:0046530)2.99201585
99cholesterol biosynthetic process (GO:0006695)2.98613514
100negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.97109969
101astrocyte development (GO:0014002)2.95251183
102cerebellar granule cell differentiation (GO:0021707)2.94851224
103regulation of renal sodium excretion (GO:0035813)2.94580239
104synapse assembly (GO:0007416)2.93737915
105regulation of excitatory postsynaptic membrane potential (GO:0060079)2.92191134
106detection of calcium ion (GO:0005513)2.91440588
107microtubule nucleation (GO:0007020)2.89845661
108membrane depolarization (GO:0051899)2.87372103
109neurotransmitter uptake (GO:0001504)2.87323419
110regulation of dendritic spine development (GO:0060998)2.87297817
111regulation of synapse maturation (GO:0090128)2.86609861
112auditory behavior (GO:0031223)2.86542010
113regulation of neurotransmitter levels (GO:0001505)2.85916375
114exploration behavior (GO:0035640)2.85349546
115peptidyl-tyrosine autophosphorylation (GO:0038083)2.83243583
116regulation of synapse structural plasticity (GO:0051823)2.81862485
117glycosphingolipid biosynthetic process (GO:0006688)2.81854039
118positive regulation of synaptic transmission (GO:0050806)2.81666761
119G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.81578619
120membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.79995115
121positive regulation of membrane potential (GO:0045838)2.79070909
122substantia nigra development (GO:0021762)2.78685844
123positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.76624308
124mechanosensory behavior (GO:0007638)2.75341944
125glycine transport (GO:0015816)2.73989795
126regulation of postsynaptic membrane potential (GO:0060078)2.72788637
127mating behavior (GO:0007617)2.72170676
128long-term memory (GO:0007616)2.70950961
129import into cell (GO:0098657)2.69231375
130establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.68990918
131mitochondrion transport along microtubule (GO:0047497)2.68990918
132regulation of synaptic plasticity (GO:0048167)2.68416527
133sterol biosynthetic process (GO:0016126)2.66792156
134membrane hyperpolarization (GO:0060081)2.65410597
135membrane tubulation (GO:0097320)2.65268218
136regulation of voltage-gated calcium channel activity (GO:1901385)2.65236061
137dendritic spine organization (GO:0097061)2.65006510
138regulation of glutamate secretion (GO:0014048)2.64384045
139regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.64344033
140positive regulation of dendritic spine development (GO:0060999)2.64223911
141neurotransmitter secretion (GO:0007269)2.64175718
142neuromuscular process controlling balance (GO:0050885)2.64036958
143positive regulation of oligodendrocyte differentiation (GO:0048714)2.63410821
144negative regulation of synaptic transmission (GO:0050805)2.63227281
145long-term synaptic potentiation (GO:0060291)2.61906678
146organelle transport along microtubule (GO:0072384)2.59918095
147cellular potassium ion homeostasis (GO:0030007)2.59695194

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.84518157
2GBX2_23144817_ChIP-Seq_PC3_Human3.67898825
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.92081543
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.85396387
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.84538767
6EZH2_18974828_ChIP-Seq_MESCs_Mouse2.45270339
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.45270339
8* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.37889102
9SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.37142940
10EZH2_27304074_Chip-Seq_ESCs_Mouse2.36340286
11SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.34057838
12* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.33279884
13JARID2_20075857_ChIP-Seq_MESCs_Mouse2.30552966
14SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.29439628
15DROSHA_22980978_ChIP-Seq_HELA_Human2.18235748
16TAF15_26573619_Chip-Seq_HEK293_Human2.17736070
17SUZ12_27294783_Chip-Seq_ESCs_Mouse2.15976138
18EZH2_27294783_Chip-Seq_ESCs_Mouse2.15083285
19EED_16625203_ChIP-ChIP_MESCs_Mouse2.13665064
20RARB_27405468_Chip-Seq_BRAIN_Mouse2.11633136
21REST_21632747_ChIP-Seq_MESCs_Mouse2.06654427
22SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.06581258
23AR_21572438_ChIP-Seq_LNCaP_Human2.05569010
24RNF2_27304074_Chip-Seq_ESCs_Mouse1.98433765
25ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.85687611
26HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.84881565
27ZFP57_27257070_Chip-Seq_ESCs_Mouse1.84307923
28RBPJ_22232070_ChIP-Seq_NCS_Mouse1.83933109
29OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.78220217
30CTBP1_25329375_ChIP-Seq_LNCAP_Human1.71315776
31SALL1_21062744_ChIP-ChIP_HESCs_Human1.69090280
32CTBP2_25329375_ChIP-Seq_LNCAP_Human1.68241966
33REST_18959480_ChIP-ChIP_MESCs_Mouse1.65813141
34FLI1_27457419_Chip-Seq_LIVER_Mouse1.64091653
35SMAD3_21741376_ChIP-Seq_EPCs_Human1.59140708
36GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.54610067
37TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.53644679
38PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.51864479
39PCGF2_27294783_Chip-Seq_ESCs_Mouse1.50334274
40CBX2_27304074_Chip-Seq_ESCs_Mouse1.48559912
41TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.46822505
42POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.46822505
43RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.45213298
44* P300_19829295_ChIP-Seq_ESCs_Human1.43792398
45PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.43035980
46* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.42701287
47CDX2_19796622_ChIP-Seq_MESCs_Mouse1.41865567
48SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.40563485
49* SMAD4_21799915_ChIP-Seq_A2780_Human1.40545458
50ER_23166858_ChIP-Seq_MCF-7_Human1.40363142
51* VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.39654437
52EWS_26573619_Chip-Seq_HEK293_Human1.38716607
53CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.36479315
54CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.36346224
55POU3F2_20337985_ChIP-ChIP_501MEL_Human1.36195379
56PIAS1_25552417_ChIP-Seq_VCAP_Human1.35384197
57MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.31856945
58NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.28588708
59GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.28451523
60* BMI1_23680149_ChIP-Seq_NPCS_Mouse1.25783656
61* STAT3_23295773_ChIP-Seq_U87_Human1.25109517
62VDR_22108803_ChIP-Seq_LS180_Human1.25082839
63P53_22127205_ChIP-Seq_FIBROBLAST_Human1.20313889
64TOP2B_26459242_ChIP-Seq_MCF-7_Human1.20090523
65TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19357347
66RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.18141156
67AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.17049803
68P53_22387025_ChIP-Seq_ESCs_Mouse1.16613709
69NR3C1_23031785_ChIP-Seq_PC12_Mouse1.15846088
70EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.15829618
71WT1_25993318_ChIP-Seq_PODOCYTE_Human1.15776587
72KDM2B_26808549_Chip-Seq_REH_Human1.15628107
73SOX2_21211035_ChIP-Seq_LN229_Gbm1.15572356
74CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.14728670
75CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14364475
76ERG_21242973_ChIP-ChIP_JURKAT_Human1.13219862
77RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.12853018
78STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.12689366
79* FUS_26573619_Chip-Seq_HEK293_Human1.12541736
80RING1B_27294783_Chip-Seq_ESCs_Mouse1.12192152
81IGF1R_20145208_ChIP-Seq_DFB_Human1.11580809
82IKZF1_21737484_ChIP-ChIP_HCT116_Human1.10458014
83PRDM14_20953172_ChIP-Seq_ESCs_Human1.10452180
84TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.10301383
85RNF2_27304074_Chip-Seq_NSC_Mouse1.09838948
86ZNF217_24962896_ChIP-Seq_MCF-7_Human1.09364502
87* TCF4_23295773_ChIP-Seq_U87_Human1.09167494
88KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.07998034
89E2F1_18555785_Chip-Seq_ESCs_Mouse1.05809345
90* RING1B_27294783_Chip-Seq_NPCs_Mouse1.05601561
91ARNT_22903824_ChIP-Seq_MCF-7_Human1.05446276
92TP53_16413492_ChIP-PET_HCT116_Human1.05249569
93TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.04008179
94* NR3C1_21868756_ChIP-Seq_MCF10A_Human1.03925409
95UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.03648347
96RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.03576156
97AHR_22903824_ChIP-Seq_MCF-7_Human1.02862458
98AR_25329375_ChIP-Seq_VCAP_Human1.01928473
99BCAT_22108803_ChIP-Seq_LS180_Human1.01564421
100CBP_20019798_ChIP-Seq_JUKART_Human1.01380889
101IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.01380889
102NANOG_18555785_Chip-Seq_ESCs_Mouse1.01128103
103* FLI1_21867929_ChIP-Seq_TH2_Mouse1.00950420
104TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.00419037
105MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.98364705
106* RUNX2_22187159_ChIP-Seq_PCA_Human0.97750744
107PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.96551843
108EP300_21415370_ChIP-Seq_HL-1_Mouse0.95132191
109CMYC_18555785_Chip-Seq_ESCs_Mouse0.94781572
110TP53_18474530_ChIP-ChIP_U2OS_Human0.94374580
111EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.91581705
112ZNF274_21170338_ChIP-Seq_K562_Hela0.91439057
113JUN_21703547_ChIP-Seq_K562_Human0.90569691
114SMAD4_21741376_ChIP-Seq_EPCs_Human0.89645678
115AR_19668381_ChIP-Seq_PC3_Human0.89628991
116MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.88867028
117LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87885347
118WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.87223969
119YAP1_20516196_ChIP-Seq_MESCs_Mouse0.87211182
120NRF2_20460467_ChIP-Seq_MEFs_Mouse0.86413314
121NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.86413314
122WT1_19549856_ChIP-ChIP_CCG9911_Human0.84976829
123LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.84816761

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010386_abnormal_urinary_bladder5.85377000
2MP0004859_abnormal_synaptic_plasticity4.99780962
3MP0003880_abnormal_central_pattern4.98436481
4MP0004270_analgesia4.03216604
5MP0000920_abnormal_myelination3.61432636
6MP0003635_abnormal_synaptic_transmissio3.40224271
7MP0002064_seizures3.03390789
8MP0009745_abnormal_behavioral_response2.94137871
9MP0001486_abnormal_startle_reflex2.91293354
10MP0002272_abnormal_nervous_system2.85034970
11MP0002063_abnormal_learning/memory/cond2.71706931
12MP0009046_muscle_twitch2.65853184
13MP0005423_abnormal_somatic_nervous2.62871824
14MP0003329_amyloid_beta_deposits2.61123531
15MP0001529_abnormal_vocalization2.42465190
16MP0002734_abnormal_mechanical_nocicepti2.41595855
17MP0002572_abnormal_emotion/affect_behav2.39761294
18MP0004885_abnormal_endolymph2.37171374
19MP0003690_abnormal_glial_cell2.34095579
20MP0000778_abnormal_nervous_system2.31355005
21MP0001968_abnormal_touch/_nociception2.23242922
22MP0001905_abnormal_dopamine_level2.21309660
23MP0002822_catalepsy2.18472408
24MP0001440_abnormal_grooming_behavior1.93952044
25MP0004742_abnormal_vestibular_system1.86946924
26MP0004142_abnormal_muscle_tone1.86387728
27MP0001970_abnormal_pain_threshold1.80045039
28MP0002733_abnormal_thermal_nociception1.76957072
29MP0008569_lethality_at_weaning1.75443530
30MP0005409_darkened_coat_color1.75370936
31MP0002735_abnormal_chemical_nociception1.74896490
32MP0003634_abnormal_glial_cell1.74508131
33MP0002067_abnormal_sensory_capabilities1.72934045
34MP0004924_abnormal_behavior1.70313473
35MP0005386_behavior/neurological_phenoty1.70313473
36MP0002736_abnormal_nociception_after1.63806529
37MP0000955_abnormal_spinal_cord1.62492125
38MP0005171_absent_coat_pigmentation1.60948554
39MP0001501_abnormal_sleep_pattern1.60673415
40MP0001485_abnormal_pinna_reflex1.56147913
41MP0002882_abnormal_neuron_morphology1.55553874
42MP0002066_abnormal_motor_capabilities/c1.50389081
43MP0002229_neurodegeneration1.49999939
44MP0003633_abnormal_nervous_system1.49468948
45MP0003631_nervous_system_phenotype1.47934186
46MP0003632_abnormal_nervous_system1.47759126
47MP0002557_abnormal_social/conspecific_i1.39191810
48MP0002184_abnormal_innervation1.36053299
49MP0003950_abnormal_plasma_membrane1.32843442
50MP0009780_abnormal_chondrocyte_physiolo1.31379957
51MP0003136_yellow_coat_color1.30702038
52MP0004811_abnormal_neuron_physiology1.30375522
53MP0000604_amyloidosis1.26974442
54MP0005410_abnormal_fertilization1.21413849
55MP0006276_abnormal_autonomic_nervous1.19574040
56MP0005646_abnormal_pituitary_gland1.16620976
57MP0005551_abnormal_eye_electrophysiolog1.16439557
58MP0001963_abnormal_hearing_physiology1.14352008
59MP0008872_abnormal_physiological_respon1.09798147
60MP0005623_abnormal_meninges_morphology1.09556483
61MP0002152_abnormal_brain_morphology1.09460772
62MP0005645_abnormal_hypothalamus_physiol1.08200283
63MP0004043_abnormal_pH_regulation1.07699179
64MP0001502_abnormal_circadian_rhythm1.05957423
65MP0008877_abnormal_DNA_methylation1.04476889
66MP0002752_abnormal_somatic_nervous1.03627139
67MP0001177_atelectasis1.02175126
68MP0000569_abnormal_digit_pigmentation1.00117070
69MP0003283_abnormal_digestive_organ0.99743084
70MP0003183_abnormal_peptide_metabolism0.97592965
71MP0004858_abnormal_nervous_system0.96114605
72MP0001299_abnormal_eye_distance/0.95291648
73MP0000462_abnormal_digestive_system0.95219514
74MP0001188_hyperpigmentation0.90396154
75MP0002751_abnormal_autonomic_nervous0.89385733
76MP0004145_abnormal_muscle_electrophysio0.88257995
77MP0001986_abnormal_taste_sensitivity0.87070450
78MP0001984_abnormal_olfaction0.85689889
79MP0005187_abnormal_penis_morphology0.85368961
80MP0002234_abnormal_pharynx_morphology0.85224254
81MP0003879_abnormal_hair_cell0.82118194
82MP0003121_genomic_imprinting0.82110625
83MP0000747_muscle_weakness0.79937971
84MP0004134_abnormal_chest_morphology0.77704757
85MP0000516_abnormal_urinary_system0.77467319
86MP0005367_renal/urinary_system_phenotyp0.77467319
87MP0001756_abnormal_urination0.77235073
88MP0010678_abnormal_skin_adnexa0.75623454
89MP0003075_altered_response_to0.74620749
90MP0003938_abnormal_ear_development0.74606889
91MP0002069_abnormal_eating/drinking_beha0.74606055
92MP0008874_decreased_physiological_sensi0.73420340
93MP0008260_abnormal_autophagy0.73296733
94MP0000026_abnormal_inner_ear0.71137541
95MP0002090_abnormal_vision0.70952287
96MP0004085_abnormal_heartbeat0.70922591
97MP0003123_paternal_imprinting0.70212249
98MP0003137_abnormal_impulse_conducting0.68261411
99MP0000631_abnormal_neuroendocrine_gland0.68174062
100MP0005195_abnormal_posterior_eye0.67535991
101MP0001348_abnormal_lacrimal_gland0.67526069
102MP0001346_abnormal_lacrimal_gland0.65006638
103MP0000751_myopathy0.63713232
104MP0002909_abnormal_adrenal_gland0.62349504
105MP0004147_increased_porphyrin_level0.61194710
106MP0001664_abnormal_digestion0.60452207
107MP0003122_maternal_imprinting0.59976411
108MP0003861_abnormal_nervous_system0.59165776
109MP0001943_abnormal_respiration0.58301484
110MP0005535_abnormal_body_temperature0.57697194
111MP0003119_abnormal_digestive_system0.56764787
112MP0002082_postnatal_lethality0.54549910
113MP0010770_preweaning_lethality0.54549910
114MP0010769_abnormal_survival0.54380362
115MP0005253_abnormal_eye_physiology0.52239916
116MP0010768_mortality/aging0.51885808
117MP0004036_abnormal_muscle_relaxation0.51187910
118MP0003787_abnormal_imprinting0.49867493
119MP0006072_abnormal_retinal_apoptosis0.49808262
120MP0004381_abnormal_hair_follicle0.49698910
121MP0002295_abnormal_pulmonary_circulatio0.48639116
122MP0000639_abnormal_adrenal_gland0.48091882
123MP0003956_abnormal_body_size0.45065224
124MP0004215_abnormal_myocardial_fiber0.39046083

Predicted human phenotypes

RankGene SetZ-score
1Degeneration of the lateral corticospinal tracts (HP:0002314)5.75477447
2Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)5.75477447
3Neurofibrillary tangles (HP:0002185)5.62654391
4Myokymia (HP:0002411)5.56009113
5Focal motor seizures (HP:0011153)5.12896712
6Abnormality of the corticospinal tract (HP:0002492)4.85439092
7Cerebral inclusion bodies (HP:0100314)4.45701833
8Termporal pattern (HP:0011008)4.45190532
9Insidious onset (HP:0003587)4.45190532
10Supranuclear gaze palsy (HP:0000605)4.27889645
11Ankle clonus (HP:0011448)3.93240236
12Spastic gait (HP:0002064)3.82834791
13Peripheral hypomyelination (HP:0007182)3.75957493
14Focal seizures (HP:0007359)3.73653302
15Dysmetria (HP:0001310)3.60124812
16Onion bulb formation (HP:0003383)3.41872125
17Intention tremor (HP:0002080)3.35168434
18Scanning speech (HP:0002168)3.30840610
19Action tremor (HP:0002345)3.27370508
20Epileptic encephalopathy (HP:0200134)3.21848678
21Inappropriate behavior (HP:0000719)3.18928484
22Genetic anticipation (HP:0003743)3.16603343
23Sensory axonal neuropathy (HP:0003390)3.12226393
24Parakeratosis (HP:0001036)3.09260057
25Broad-based gait (HP:0002136)2.93515879
26Urinary urgency (HP:0000012)2.85951454
27Tetraplegia (HP:0002445)2.85577813
28Atonic seizures (HP:0010819)2.85540988
29Megalencephaly (HP:0001355)2.85102843
30Increased density of long bones (HP:0006392)2.84430455
31Abnormality of the labia minora (HP:0012880)2.77837742
32Amyotrophic lateral sclerosis (HP:0007354)2.74173628
33Lower limb muscle weakness (HP:0007340)2.72695598
34Pheochromocytoma (HP:0002666)2.71114661
35Retinal dysplasia (HP:0007973)2.70369129
36Protruding tongue (HP:0010808)2.68079247
37Abnormal auditory evoked potentials (HP:0006958)2.66759392
38Dialeptic seizures (HP:0011146)2.62028339
39Disinhibition (HP:0000734)2.61466588
40Apathy (HP:0000741)2.61284562
41Akinesia (HP:0002304)2.59971222
42Visual hallucinations (HP:0002367)2.59386403
43Progressive cerebellar ataxia (HP:0002073)2.58842572
44Clumsiness (HP:0002312)2.54000631
45Urinary bladder sphincter dysfunction (HP:0002839)2.53994464
46Epileptiform EEG discharges (HP:0011182)2.53952720
47Hyperventilation (HP:0002883)2.53344793
48Calf muscle hypertrophy (HP:0008981)2.48815247
49Dysdiadochokinesis (HP:0002075)2.46498235
50Hepatoblastoma (HP:0002884)2.45644237
51Generalized tonic-clonic seizures (HP:0002069)2.45153416
52Impaired vibration sensation in the lower limbs (HP:0002166)2.45049851
53Thickened helices (HP:0000391)2.44313789
54Hip dysplasia (HP:0001385)2.42081638
55Clonus (HP:0002169)2.41997537
56Agitation (HP:0000713)2.38297726
57Alacrima (HP:0000522)2.37634815
58Absence seizures (HP:0002121)2.37458064
59Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.36987327
60Intellectual disability, severe (HP:0010864)2.34848485
61EEG with generalized epileptiform discharges (HP:0011198)2.34722715
62Progressive inability to walk (HP:0002505)2.34705891
63Abnormality of salivation (HP:0100755)2.34574718
64Truncal ataxia (HP:0002078)2.34286103
65Neuroendocrine neoplasm (HP:0100634)2.33032065
66Difficulty running (HP:0009046)2.32417754
67Slow saccadic eye movements (HP:0000514)2.31702073
68Hypsarrhythmia (HP:0002521)2.31271727
69Diminished motivation (HP:0000745)2.31042973
70Gaze-evoked nystagmus (HP:0000640)2.30283560
71Aplasia involving bones of the upper limbs (HP:0009823)2.30279104
72Aplasia of the phalanges of the hand (HP:0009802)2.30279104
73Aplasia involving bones of the extremities (HP:0009825)2.30279104
74Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.29750377
75Mutism (HP:0002300)2.28881531
76Cerebral hypomyelination (HP:0006808)2.28565317
77Hemiplegia (HP:0002301)2.26433879
78Anteriorly placed anus (HP:0001545)2.24614978
79Impaired vibratory sensation (HP:0002495)2.24270239
80Hemiparesis (HP:0001269)2.23798324
81Abnormal eating behavior (HP:0100738)2.22304533
82Anxiety (HP:0000739)2.21654470
83Poor eye contact (HP:0000817)2.21279544
84Increased circulating renin level (HP:0000848)2.20432613
85Generalized myoclonic seizures (HP:0002123)2.19729939
86Muscle hypertrophy of the lower extremities (HP:0008968)2.19728857
87Spastic tetraparesis (HP:0001285)2.19028285
88Polyphagia (HP:0002591)2.18953172
89Segmental peripheral demyelination/remyelination (HP:0003481)2.15724185
90Inability to walk (HP:0002540)2.14581561
91Limb dystonia (HP:0002451)2.13962204
92Cerebral hemorrhage (HP:0001342)2.12921628
93Morphological abnormality of the pyramidal tract (HP:0002062)2.11803267
94Leukodystrophy (HP:0002415)2.11511693
95Fetal akinesia sequence (HP:0001989)2.08841861
96Drooling (HP:0002307)2.05981325
97Excessive salivation (HP:0003781)2.05981325
98Hammertoe (HP:0001765)2.05246186
99Split foot (HP:0001839)2.04587449
100Neuronal loss in central nervous system (HP:0002529)2.03246624
101Thoracolumbar scoliosis (HP:0002944)2.02283005
102Postural instability (HP:0002172)2.02193616
103Absent speech (HP:0001344)1.98942452
104Paraplegia (HP:0010550)1.98734019
105Foot dorsiflexor weakness (HP:0009027)1.98200529
106Depression (HP:0000716)1.98196677
107Abnormality of ocular smooth pursuit (HP:0000617)1.96630105
108Decreased motor nerve conduction velocity (HP:0003431)1.95830084
109Incomplete penetrance (HP:0003829)1.95092736
110Blue irides (HP:0000635)1.94949716
111Decreased muscle mass (HP:0003199)1.94809277
112Febrile seizures (HP:0002373)1.94788273
113Aplasia/Hypoplasia of the tibia (HP:0005772)1.94392150
114Stereotypic behavior (HP:0000733)1.94085994
115Torticollis (HP:0000473)1.92797218
116Type II lissencephaly (HP:0007260)1.89211833
117Abnormal social behavior (HP:0012433)1.89183545
118Impaired social interactions (HP:0000735)1.89183545
119Bowel incontinence (HP:0002607)1.88443989
120Decreased lacrimation (HP:0000633)1.88316871
121Diplopia (HP:0000651)1.87995101
122Abnormality of binocular vision (HP:0011514)1.87995101
123Syncope (HP:0001279)1.85136110
124Status epilepticus (HP:0002133)1.85040230
125Absent septum pellucidum (HP:0001331)1.84328728
126Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.84259652
127Short 1st metacarpal (HP:0010034)1.84259652
128Impaired smooth pursuit (HP:0007772)1.84076780
129Hypoplasia of the corpus callosum (HP:0002079)1.81242496
130Abnormality of the foot musculature (HP:0001436)1.80610159
131Amblyopia (HP:0000646)1.80332017
132Spastic paraplegia (HP:0001258)1.79781837
133Metabolic alkalosis (HP:0200114)1.78400652
134Long nose (HP:0003189)1.77630346
135CNS hypomyelination (HP:0003429)1.74783957
136Distal sensory impairment (HP:0002936)1.74388722
137Dynein arm defect of respiratory motile cilia (HP:0012255)1.74339942
138Absent/shortened dynein arms (HP:0200106)1.74339942
139Focal dystonia (HP:0004373)1.74038567
140Abnormality of saccadic eye movements (HP:0000570)1.73826106
141Coronal craniosynostosis (HP:0004440)1.73789975
142Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.72808096

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK394.50338164
2OXSR13.35973655
3EPHA43.33886897
4MARK12.83370342
5MAP3K92.43078344
6NTRK32.40691127
7EPHB12.18662948
8CDK192.09510218
9PNCK2.03078424
10BCR2.02987306
11PAK62.02507001
12TNIK2.01288087
13NTRK11.97080005
14MAPKAPK51.96514542
15CCNB11.92890874
16PKN11.92706062
17SIK21.87547780
18UHMK11.85999886
19WNK41.75633901
20CASK1.70194489
21FRK1.69831884
22FGFR21.65726729
23KSR21.64916682
24MAP3K41.64916064
25CAMK2B1.56975911
26WNK11.56264679
27PRPF4B1.54787742
28NTRK21.54191969
29LIMK11.50654922
30MINK11.49143896
31SGK21.48865432
32CDK51.41888402
33ARAF1.35877450
34CSNK1G21.34007472
35DAPK21.33463436
36MAP4K21.31659675
37CSNK1G31.30932459
38TYRO31.30325015
39DAPK11.30091843
40MAP2K71.22833719
41CSNK1A1L1.22660470
42SGK2231.22050012
43SGK4941.22050012
44MAP3K131.15051210
45CAMK2D1.13720143
46NEK61.13472483
47FGR1.12796360
48CAMK2A1.09223256
49ROCK21.08779889
50PRKD31.08256369
51MAPK131.06855787
52CDK141.04744234
53MET1.03342182
54CDK150.98410856
55PAK30.98107201
56CAMK40.98031290
57MARK20.97561864
58MAP3K60.97337109
59CDK180.96584516
60PHKG10.94758419
61PHKG20.94758419
62KSR10.93876117
63CAMKK20.93353679
64CAMK2G0.93175010
65FES0.91466005
66PBK0.90476663
67SGK30.89207132
68CSNK1G10.87958936
69CDK11A0.87596249
70RPS6KA40.87478858
71ROCK10.83055111
72TESK20.82627230
73MAP3K20.82130011
74PLK20.80864098
75CLK10.79684202
76MAP2K40.78555565
77DYRK20.78183277
78ICK0.75672770
79GRK50.75204023
80RIPK40.73288774
81PDPK10.73251938
82STK110.71634600
83PRKCE0.71042743
84CAMK1G0.65407593
85PRKCG0.65218044
86IRAK20.63542843
87PRKCQ0.61435340
88MAPK40.61403279
89MUSK0.61026048
90FYN0.60268406
91PRKCH0.59545696
92PTK2B0.58623076
93CAMKK10.57922860
94DYRK30.57154242
95BMPR20.55662289
96PDK10.54564587
97DYRK1A0.54427508
98SGK10.51853076
99PRKD10.51682391
100PINK10.50964866
101LATS20.50351470
102CAMK10.48849452
103FLT30.47030241
104NUAK10.46734175
105RET0.45798571
106DMPK0.45723565
107CSNK1D0.44210115
108PRKG10.43842945
109RAF10.43832542
110PRKACA0.42184644
111PRKACB0.41201021
112CDK30.39094680
113TAOK30.38229288
114CSNK1A10.38226897
115RPS6KB10.37740742
116MAPK120.37590120
117MAPK100.36676717
118DAPK30.35619094
119ERBB40.34317230
120BMPR1B0.34169053
121PRKCB0.33407005
122PRKCZ0.33253790
123MAP3K120.33155100
124RPS6KA30.32620105
125ALK0.29913954
126ERBB30.29336983
127GSK3B0.28046711
128PRKCA0.27754787
129PKN20.26904377
130MAPK70.25927423
131WNK30.25746303

Predicted pathways (KEGG)

RankGene SetZ-score
1Terpenoid backbone biosynthesis_Homo sapiens_hsa009003.37664849
2Steroid biosynthesis_Homo sapiens_hsa001002.61654048
3Nicotine addiction_Homo sapiens_hsa050332.60427352
4GABAergic synapse_Homo sapiens_hsa047272.49591619
5Glutamatergic synapse_Homo sapiens_hsa047242.40119038
6Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.29121399
7Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.26016181
8Synaptic vesicle cycle_Homo sapiens_hsa047212.21495484
9Morphine addiction_Homo sapiens_hsa050322.21248820
10Fatty acid elongation_Homo sapiens_hsa000622.20305495
11Circadian entrainment_Homo sapiens_hsa047132.14556965
12Olfactory transduction_Homo sapiens_hsa047401.90969973
13Ether lipid metabolism_Homo sapiens_hsa005651.86856409
14Serotonergic synapse_Homo sapiens_hsa047261.86801339
15Axon guidance_Homo sapiens_hsa043601.82486744
16Amphetamine addiction_Homo sapiens_hsa050311.82157121
17Dopaminergic synapse_Homo sapiens_hsa047281.82076096
18Long-term potentiation_Homo sapiens_hsa047201.81830513
19Long-term depression_Homo sapiens_hsa047301.73594255
20Salivary secretion_Homo sapiens_hsa049701.70242869
21Cocaine addiction_Homo sapiens_hsa050301.69008214
22Cholinergic synapse_Homo sapiens_hsa047251.59833719
23Nitrogen metabolism_Homo sapiens_hsa009101.57265469
24Gastric acid secretion_Homo sapiens_hsa049711.50120645
25Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.49587863
26Renin secretion_Homo sapiens_hsa049241.38981608
27Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.35492301
28Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.32894608
29Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.32360440
30Collecting duct acid secretion_Homo sapiens_hsa049661.31859268
31Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.26529372
32Insulin secretion_Homo sapiens_hsa049111.24218680
33Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.23739989
34Taste transduction_Homo sapiens_hsa047421.21781971
35Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.21636114
36Oxytocin signaling pathway_Homo sapiens_hsa049211.19312229
37Gap junction_Homo sapiens_hsa045401.15519075
38Aldosterone synthesis and secretion_Homo sapiens_hsa049251.12754677
39Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.09559537
40Butanoate metabolism_Homo sapiens_hsa006501.06694125
41Oxidative phosphorylation_Homo sapiens_hsa001901.06184641
42Dorso-ventral axis formation_Homo sapiens_hsa043201.05172042
43Calcium signaling pathway_Homo sapiens_hsa040201.04722981
44Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.04268271
45Renal cell carcinoma_Homo sapiens_hsa052111.02600032
46Bile secretion_Homo sapiens_hsa049761.02170800
47Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.98842649
48ErbB signaling pathway_Homo sapiens_hsa040120.98465141
49Vibrio cholerae infection_Homo sapiens_hsa051100.98236708
50cAMP signaling pathway_Homo sapiens_hsa040240.97705943
51Vascular smooth muscle contraction_Homo sapiens_hsa042700.97397306
52Cardiac muscle contraction_Homo sapiens_hsa042600.96624658
53Sphingolipid signaling pathway_Homo sapiens_hsa040710.95390909
54GnRH signaling pathway_Homo sapiens_hsa049120.94743801
55Alzheimers disease_Homo sapiens_hsa050100.94702983
56Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.94617053
57Phospholipase D signaling pathway_Homo sapiens_hsa040720.93502213
58Circadian rhythm_Homo sapiens_hsa047100.90338967
59Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.89966006
60Vitamin B6 metabolism_Homo sapiens_hsa007500.88995584
61Sphingolipid metabolism_Homo sapiens_hsa006000.87561377
62Sulfur metabolism_Homo sapiens_hsa009200.86441058
63Phototransduction_Homo sapiens_hsa047440.85426831
64Ras signaling pathway_Homo sapiens_hsa040140.84539857
65SNARE interactions in vesicular transport_Homo sapiens_hsa041300.82256425
66Parkinsons disease_Homo sapiens_hsa050120.81978779
67Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.81636124
68beta-Alanine metabolism_Homo sapiens_hsa004100.80188332
69Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.75916291
70Pancreatic secretion_Homo sapiens_hsa049720.75891044
71Melanogenesis_Homo sapiens_hsa049160.75694652
72Phosphatidylinositol signaling system_Homo sapiens_hsa040700.73755387
73Choline metabolism in cancer_Homo sapiens_hsa052310.72459038
74Estrogen signaling pathway_Homo sapiens_hsa049150.71484249
75Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.70347914
76Endocytosis_Homo sapiens_hsa041440.69480328
77Regulation of autophagy_Homo sapiens_hsa041400.68463031
78cGMP-PKG signaling pathway_Homo sapiens_hsa040220.68192348
79Tight junction_Homo sapiens_hsa045300.67541653
80Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.60595794
81MAPK signaling pathway_Homo sapiens_hsa040100.59977995
82Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.59929035
83Glioma_Homo sapiens_hsa052140.58368181
84Linoleic acid metabolism_Homo sapiens_hsa005910.56794294
85Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.55770160
86Ovarian steroidogenesis_Homo sapiens_hsa049130.55151913
87Prion diseases_Homo sapiens_hsa050200.54931008
88Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.52117597
89Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.51767961
90Glycerophospholipid metabolism_Homo sapiens_hsa005640.51023897
91alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.50854933
92Alcoholism_Homo sapiens_hsa050340.50313850
93Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.49717762
94Type II diabetes mellitus_Homo sapiens_hsa049300.49427690
95Longevity regulating pathway - mammal_Homo sapiens_hsa042110.49288088
96Carbohydrate digestion and absorption_Homo sapiens_hsa049730.47342201
97Rap1 signaling pathway_Homo sapiens_hsa040150.46997359
98Inositol phosphate metabolism_Homo sapiens_hsa005620.46363366
99Dilated cardiomyopathy_Homo sapiens_hsa054140.45649778
100Histidine metabolism_Homo sapiens_hsa003400.45273578
101Glucagon signaling pathway_Homo sapiens_hsa049220.44303022
102Thyroid hormone synthesis_Homo sapiens_hsa049180.43845471
103Rheumatoid arthritis_Homo sapiens_hsa053230.38819739
104Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.37760928
105Fatty acid biosynthesis_Homo sapiens_hsa000610.37166552
106Regulation of actin cytoskeleton_Homo sapiens_hsa048100.37009754
107Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.36787413
108VEGF signaling pathway_Homo sapiens_hsa043700.36008880
109Oocyte meiosis_Homo sapiens_hsa041140.35913841
110Neurotrophin signaling pathway_Homo sapiens_hsa047220.35873487
111Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.35505343
112Wnt signaling pathway_Homo sapiens_hsa043100.33887225
113Platelet activation_Homo sapiens_hsa046110.33777410
114Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.32675943
115mTOR signaling pathway_Homo sapiens_hsa041500.31673055
116Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.29011571
117ABC transporters_Homo sapiens_hsa020100.27503844
118AMPK signaling pathway_Homo sapiens_hsa041520.27195731
119Hippo signaling pathway_Homo sapiens_hsa043900.22521678
120Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.20093886
121Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.17682231
122Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.15243975

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