Rank | Gene Set | Z-score |
---|---|---|
1 | cytidine metabolic process (GO:0046087) | 8.33480700 |
2 | cytidine catabolic process (GO:0006216) | 8.33480700 |
3 | cytidine deamination (GO:0009972) | 8.33480700 |
4 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 7.50975873 |
5 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 6.83620186 |
6 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.66327007 |
7 | interferon-gamma production (GO:0032609) | 5.57948790 |
8 | negative T cell selection (GO:0043383) | 5.43843062 |
9 | negative thymic T cell selection (GO:0045060) | 5.28581099 |
10 | positive thymic T cell selection (GO:0045059) | 5.21391742 |
11 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 5.16648417 |
12 | cellular response to interleukin-15 (GO:0071350) | 5.11446374 |
13 | leukocyte aggregation (GO:0070486) | 4.98280565 |
14 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.92444628 |
15 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.92444628 |
16 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.91343377 |
17 | DNA deamination (GO:0045006) | 4.91102545 |
18 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.71461506 |
19 | negative regulation of cell killing (GO:0031342) | 4.71461506 |
20 | regulation of activation of Janus kinase activity (GO:0010533) | 4.69976703 |
21 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.69049667 |
22 | regulation of regulatory T cell differentiation (GO:0045589) | 4.59251970 |
23 | regulation of lymphocyte chemotaxis (GO:1901623) | 4.54712868 |
24 | regulation of natural killer cell mediated immunity (GO:0002715) | 4.51328033 |
25 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 4.51328033 |
26 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 4.51289189 |
27 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 4.51289189 |
28 | thymic T cell selection (GO:0045061) | 4.51076281 |
29 | positive T cell selection (GO:0043368) | 4.50862230 |
30 | response to interleukin-15 (GO:0070672) | 4.49998444 |
31 | negative regulation by host of viral transcription (GO:0043922) | 4.48515153 |
32 | T cell migration (GO:0072678) | 4.48463065 |
33 | mast cell activation (GO:0045576) | 4.43457992 |
34 | ribosomal small subunit assembly (GO:0000028) | 4.41330870 |
35 | cytolysis (GO:0019835) | 4.37594616 |
36 | negative regulation of phagocytosis (GO:0050765) | 4.36316437 |
37 | eosinophil chemotaxis (GO:0048245) | 4.35684400 |
38 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.33730532 |
39 | negative regulation of T cell apoptotic process (GO:0070233) | 4.26227170 |
40 | cellular response to zinc ion (GO:0071294) | 4.24789793 |
41 | sequestering of actin monomers (GO:0042989) | 4.20474703 |
42 | positive regulation of calcium-mediated signaling (GO:0050850) | 4.15899237 |
43 | negative regulation of viral genome replication (GO:0045071) | 4.14039234 |
44 | macrophage chemotaxis (GO:0048246) | 4.10428627 |
45 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 4.10330071 |
46 | regulation of T cell receptor signaling pathway (GO:0050856) | 4.03906474 |
47 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 4.00448947 |
48 | regulation of T cell chemotaxis (GO:0010819) | 4.00401394 |
49 | positive regulation of T cell chemotaxis (GO:0010820) | 4.00401394 |
50 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.97720911 |
51 | eosinophil migration (GO:0072677) | 3.96097719 |
52 | positive regulation of B cell differentiation (GO:0045579) | 3.89718307 |
53 | positive regulation of lymphocyte migration (GO:2000403) | 3.87124420 |
54 | positive regulation of interleukin-8 secretion (GO:2000484) | 3.86499639 |
55 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.86069273 |
56 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.85796760 |
57 | regulation of gamma-delta T cell activation (GO:0046643) | 3.84391785 |
58 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.80206737 |
59 | positive regulation of isotype switching (GO:0045830) | 3.79882998 |
60 | T cell selection (GO:0045058) | 3.79631461 |
61 | granulocyte activation (GO:0036230) | 3.77873570 |
62 | regulation of chronic inflammatory response (GO:0002676) | 3.74498250 |
63 | pyrimidine nucleoside catabolic process (GO:0046135) | 3.73878245 |
64 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.72021251 |
65 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.71710993 |
66 | positive regulation of monocyte chemotaxis (GO:0090026) | 3.69072332 |
67 | T cell receptor signaling pathway (GO:0050852) | 3.67988450 |
68 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.65544530 |
69 | lymphocyte chemotaxis (GO:0048247) | 3.65470694 |
70 | regulation of T cell tolerance induction (GO:0002664) | 3.60828020 |
71 | positive regulation of lamellipodium assembly (GO:0010592) | 3.60724949 |
72 | negative regulation of T cell receptor signaling pathway (GO:0050860) | 3.60250805 |
73 | positive regulation of B cell mediated immunity (GO:0002714) | 3.60086855 |
74 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 3.60086855 |
75 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.59517773 |
76 | T cell costimulation (GO:0031295) | 3.58677956 |
77 | actin nucleation (GO:0045010) | 3.57941846 |
78 | positive regulation of cell killing (GO:0031343) | 3.54304622 |
79 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 3.53778351 |
80 | dendritic cell chemotaxis (GO:0002407) | 3.53085605 |
81 | lymphocyte costimulation (GO:0031294) | 3.52103916 |
82 | negative regulation of growth of symbiont in host (GO:0044130) | 3.51906521 |
83 | negative regulation of growth of symbiont involved in interaction with host (GO:0044146) | 3.51906521 |
84 | modulation of growth of symbiont involved in interaction with host (GO:0044144) | 3.51906521 |
85 | regulation of growth of symbiont in host (GO:0044126) | 3.51906521 |
86 | regulation of cell killing (GO:0031341) | 3.49001848 |
87 | regulation of B cell differentiation (GO:0045577) | 3.45699470 |
88 | neutrophil activation (GO:0042119) | 3.44197953 |
89 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.43869800 |
90 | positive regulation of defense response to virus by host (GO:0002230) | 3.42553674 |
91 | neutrophil mediated immunity (GO:0002446) | 3.41595398 |
92 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 3.41403511 |
93 | regulation of lymphocyte migration (GO:2000401) | 3.37584627 |
94 | regulation of B cell mediated immunity (GO:0002712) | 3.37303938 |
95 | DNA strand elongation (GO:0022616) | 3.36161094 |
96 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.36136467 |
97 | regulation of immunoglobulin mediated immune response (GO:0002889) | 3.36083004 |
98 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.35573955 |
99 | regulation of T cell mediated cytotoxicity (GO:0001914) | 3.34687707 |
100 | negative regulation of T cell mediated immunity (GO:0002710) | 3.32829396 |
101 | immunoglobulin mediated immune response (GO:0016064) | 3.32661029 |
102 | positive regulation of tolerance induction (GO:0002645) | 3.31065280 |
103 | positive regulation of DNA recombination (GO:0045911) | 3.30824420 |
104 | positive regulation of immune response to tumor cell (GO:0002839) | 3.30615615 |
105 | regulation of immune response to tumor cell (GO:0002837) | 3.30615615 |
106 | regulation of response to tumor cell (GO:0002834) | 3.30615615 |
107 | positive regulation of response to tumor cell (GO:0002836) | 3.30615615 |
108 | positive regulation of T cell apoptotic process (GO:0070234) | 3.25586758 |
109 | killing of cells in other organism involved in symbiotic interaction (GO:0051883) | 3.25054224 |
110 | disruption of cells of other organism involved in symbiotic interaction (GO:0051818) | 3.25054224 |
111 | cellular defense response (GO:0006968) | 3.23655402 |
112 | positive regulation of lymphocyte mediated immunity (GO:0002708) | 3.22820675 |
113 | natural killer cell activation (GO:0030101) | 3.22291603 |
114 | regulation of T cell apoptotic process (GO:0070232) | 3.20668376 |
115 | activated T cell proliferation (GO:0050798) | 3.18291794 |
116 | negative regulation of interleukin-12 production (GO:0032695) | 3.15938774 |
117 | myeloid leukocyte mediated immunity (GO:0002444) | 3.12978430 |
118 | regulation of isotype switching (GO:0045191) | 3.12943967 |
119 | chemokine-mediated signaling pathway (GO:0070098) | 3.12692026 |
120 | regulation of calcium-mediated signaling (GO:0050848) | 3.11280496 |
121 | monocyte chemotaxis (GO:0002548) | 3.11128098 |
122 | respiratory burst (GO:0045730) | 3.10722351 |
123 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.10677176 |
124 | leukocyte mediated cytotoxicity (GO:0001909) | 3.10047535 |
125 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.09805432 |
126 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.09665732 |
127 | signal peptide processing (GO:0006465) | 3.09322838 |
128 | negative regulation of lymphocyte apoptotic process (GO:0070229) | 3.08716730 |
129 | leukocyte degranulation (GO:0043299) | 3.08275814 |
130 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.07745020 |
131 | leukocyte cell-cell adhesion (GO:0007159) | 3.05865158 |
132 | dendritic cell migration (GO:0036336) | 3.05240398 |
133 | telomere maintenance via recombination (GO:0000722) | 3.04092864 |
134 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 2.99418388 |
135 | viral transcription (GO:0019083) | 2.97255594 |
136 | regulation of response to interferon-gamma (GO:0060330) | 2.96039122 |
137 | regulation of interferon-gamma-mediated signaling pathway (GO:0060334) | 2.94317217 |
138 | regulation of lymphocyte mediated immunity (GO:0002706) | 2.93233564 |
139 | cotranslational protein targeting to membrane (GO:0006613) | 2.92463349 |
140 | B cell receptor signaling pathway (GO:0050853) | 2.92353128 |
141 | lymphocyte migration (GO:0072676) | 2.91740821 |
142 | positive regulation of immunoglobulin production (GO:0002639) | 2.90262514 |
143 | protein targeting to ER (GO:0045047) | 2.89737062 |
144 | translational termination (GO:0006415) | 2.89723683 |
145 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.88787985 |
146 | regulation of tolerance induction (GO:0002643) | 2.85397977 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 6.62319548 |
2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.88307434 |
3 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.49596939 |
4 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.25267285 |
5 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.16432346 |
6 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.10909426 |
7 | * STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.95200595 |
8 | * MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.94423578 |
9 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.90173814 |
10 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.83140846 |
11 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.72789267 |
12 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.66643287 |
13 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.55992145 |
14 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.52200698 |
15 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.50076566 |
16 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.47401712 |
17 | * FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 2.44957144 |
18 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.44686687 |
19 | * MYB_26560356_Chip-Seq_TH2_Human | 2.34765170 |
20 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.34417615 |
21 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.34382795 |
22 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.33814293 |
23 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.25764881 |
24 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.22994245 |
25 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.15955725 |
26 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.15708802 |
27 | MYC_22102868_ChIP-Seq_BL_Human | 2.10930124 |
28 | * SPI1_23547873_ChIP-Seq_NB4_Human | 2.09694184 |
29 | MAF_26560356_Chip-Seq_TH1_Human | 2.08673581 |
30 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.07971246 |
31 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.06685478 |
32 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.05267411 |
33 | * MYB_26560356_Chip-Seq_TH1_Human | 2.05196843 |
34 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.00937658 |
35 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.98407277 |
36 | UTX_26944678_Chip-Seq_JUKART_Human | 1.96250490 |
37 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.93534512 |
38 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.87512255 |
39 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.87371417 |
40 | * RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.82271768 |
41 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.81832447 |
42 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.80829606 |
43 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.80803874 |
44 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.80132065 |
45 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.77611333 |
46 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.74911944 |
47 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.70362950 |
48 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.68154642 |
49 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.67268491 |
50 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.66899451 |
51 | * MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.66621257 |
52 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.63529783 |
53 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.53783938 |
54 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.52831950 |
55 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.49862615 |
56 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.49457877 |
57 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.48162648 |
58 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.46086298 |
59 | GATA1_22025678_ChIP-Seq_K562_Human | 1.43595435 |
60 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.42957671 |
61 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.42785816 |
62 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.41372469 |
63 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.41102982 |
64 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.41067104 |
65 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.40826765 |
66 | MAF_26560356_Chip-Seq_TH2_Human | 1.40641816 |
67 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.39545809 |
68 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.38856771 |
69 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.38826135 |
70 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.36231272 |
71 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.36162261 |
72 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.31333079 |
73 | * GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.29792283 |
74 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.27917693 |
75 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.27379775 |
76 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.26581680 |
77 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.25107815 |
78 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.24730115 |
79 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.22047594 |
80 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.21189861 |
81 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.20734297 |
82 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.18863256 |
83 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.18706109 |
84 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.17387216 |
85 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.16963997 |
86 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.16731272 |
87 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.16401372 |
88 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.14926846 |
89 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.12878330 |
90 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.12623905 |
91 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.10929396 |
92 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.07962942 |
93 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.06089925 |
94 | GATA3_26560356_Chip-Seq_TH2_Human | 1.05822180 |
95 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.05122621 |
96 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.04638468 |
97 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.03953478 |
98 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.03854298 |
99 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.03789284 |
100 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.03777731 |
101 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.01878500 |
102 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.00762786 |
103 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.00581795 |
104 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.99765504 |
105 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.98942122 |
106 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.95099226 |
107 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.94263138 |
108 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.93428286 |
109 | SPI1_23127762_ChIP-Seq_K562_Human | 0.93342227 |
110 | PU_27001747_Chip-Seq_BMDM_Mouse | 0.93238372 |
111 | P300_27268052_Chip-Seq_Bcells_Human | 0.92473183 |
112 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.92217556 |
113 | VDR_24787735_ChIP-Seq_THP-1_Human | 0.92108223 |
114 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.91825065 |
115 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.91267067 |
116 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.91090939 |
117 | GATA3_26560356_Chip-Seq_TH1_Human | 0.90001360 |
118 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.87809879 |
119 | SA1_27219007_Chip-Seq_Bcells_Human | 0.87100151 |
120 | * TAF2_19829295_ChIP-Seq_ESCs_Human | 0.86988406 |
121 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.83252058 |
122 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.82819221 |
123 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.82778302 |
124 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.79168173 |
125 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.78866418 |
126 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.78372590 |
127 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.77336950 |
128 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.74827025 |
129 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.74585860 |
130 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.74548553 |
131 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.74297904 |
132 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.72688198 |
133 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.72526059 |
134 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.70908796 |
135 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.70590591 |
136 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.68677688 |
137 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.67977583 |
138 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.67429748 |
139 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.64996065 |
140 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.64501275 |
141 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.64286129 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005671_abnormal_response_to | 5.41510086 |
2 | MP0003763_abnormal_thymus_physiology | 4.73707866 |
3 | MP0009785_altered_susceptibility_to | 3.74499660 |
4 | MP0001835_abnormal_antigen_presentation | 3.13456164 |
5 | MP0002396_abnormal_hematopoietic_system | 3.05547060 |
6 | MP0006082_CNS_inflammation | 2.98021373 |
7 | MP0005025_abnormal_response_to | 2.93515458 |
8 | MP0002420_abnormal_adaptive_immunity | 2.91382127 |
9 | MP0001819_abnormal_immune_cell | 2.85985140 |
10 | MP0002166_altered_tumor_susceptibility | 2.83259984 |
11 | MP0003724_increased_susceptibility_to | 2.75657764 |
12 | MP0005000_abnormal_immune_tolerance | 2.75623442 |
13 | MP0001800_abnormal_humoral_immune | 2.72787185 |
14 | MP0002398_abnormal_bone_marrow | 2.71038413 |
15 | MP0000685_abnormal_immune_system | 2.69751381 |
16 | MP0002723_abnormal_immune_serum | 2.54636590 |
17 | MP0002006_tumorigenesis | 2.48359220 |
18 | MP0009333_abnormal_splenocyte_physiolog | 2.47055677 |
19 | MP0000858_altered_metastatic_potential | 2.42598999 |
20 | MP0000716_abnormal_immune_system | 2.39138658 |
21 | MP0002405_respiratory_system_inflammati | 2.38455654 |
22 | MP0002452_abnormal_antigen_presenting | 2.33817626 |
23 | MP0003693_abnormal_embryo_hatching | 2.32936715 |
24 | MP0002722_abnormal_immune_system | 2.29696328 |
25 | MP0002419_abnormal_innate_immunity | 2.25493079 |
26 | MP0000703_abnormal_thymus_morphology | 2.25088137 |
27 | MP0005387_immune_system_phenotype | 2.24227898 |
28 | MP0001790_abnormal_immune_system | 2.24227898 |
29 | MP0002148_abnormal_hypersensitivity_rea | 2.16881946 |
30 | MP0000689_abnormal_spleen_morphology | 2.13511504 |
31 | MP0005464_abnormal_platelet_physiology | 2.09651548 |
32 | MP0001873_stomach_inflammation | 2.04569552 |
33 | MP0003436_decreased_susceptibility_to | 2.04129853 |
34 | MP0002429_abnormal_blood_cell | 2.02895806 |
35 | MP0008057_abnormal_DNA_replication | 2.00897355 |
36 | MP0010155_abnormal_intestine_physiology | 1.89139469 |
37 | MP0000490_abnormal_crypts_of | 1.86882907 |
38 | MP0010094_abnormal_chromosome_stability | 1.82106483 |
39 | MP0003866_abnormal_defecation | 1.81286917 |
40 | MP0005075_abnormal_melanosome_morpholog | 1.77503755 |
41 | MP0002132_abnormal_respiratory_system | 1.70635454 |
42 | MP0001845_abnormal_inflammatory_respons | 1.68025817 |
43 | MP0003448_altered_tumor_morphology | 1.66889344 |
44 | MP0004957_abnormal_blastocyst_morpholog | 1.62371519 |
45 | MP0002019_abnormal_tumor_incidence | 1.56605517 |
46 | MP0003045_fibrosis | 1.54445087 |
47 | MP0004947_skin_inflammation | 1.47350781 |
48 | MP0000465_gastrointestinal_hemorrhage | 1.46953692 |
49 | MP0002933_joint_inflammation | 1.42243212 |
50 | MP0003111_abnormal_nucleus_morphology | 1.38491689 |
51 | MP0003077_abnormal_cell_cycle | 1.37314835 |
52 | MP0001853_heart_inflammation | 1.32750247 |
53 | MP0006054_spinal_hemorrhage | 1.31560720 |
54 | MP0005174_abnormal_tail_pigmentation | 1.30261039 |
55 | MP0004808_abnormal_hematopoietic_stem | 1.29772594 |
56 | MP0008007_abnormal_cellular_replicative | 1.27573540 |
57 | MP0008058_abnormal_DNA_repair | 1.26852538 |
58 | MP0003172_abnormal_lysosome_physiology | 1.26084376 |
59 | MP0002277_abnormal_respiratory_mucosa | 1.25930978 |
60 | MP0002009_preneoplasia | 1.24987321 |
61 | MP0001545_abnormal_hematopoietic_system | 1.24718793 |
62 | MP0005397_hematopoietic_system_phenotyp | 1.24718793 |
63 | MP0002163_abnormal_gland_morphology | 1.20152576 |
64 | MP0001851_eye_inflammation | 1.18412102 |
65 | MP0008469_abnormal_protein_level | 1.18071168 |
66 | MP0004381_abnormal_hair_follicle | 1.17809210 |
67 | MP0001533_abnormal_skeleton_physiology | 1.10064010 |
68 | MP0002095_abnormal_skin_pigmentation | 1.06501765 |
69 | MP0009763_increased_sensitivity_to | 1.02420856 |
70 | MP0000015_abnormal_ear_pigmentation | 0.97291600 |
71 | MP0003075_altered_response_to | 0.90221508 |
72 | MP0002693_abnormal_pancreas_physiology | 0.81679970 |
73 | MP0002138_abnormal_hepatobiliary_system | 0.76843794 |
74 | MP0010352_gastrointestinal_tract_polyps | 0.76145227 |
75 | MP0010307_abnormal_tumor_latency | 0.74839303 |
76 | MP0003786_premature_aging | 0.74609004 |
77 | MP0001986_abnormal_taste_sensitivity | 0.72668356 |
78 | MP0003300_gastrointestinal_ulcer | 0.71748572 |
79 | MP0002998_abnormal_bone_remodeling | 0.71205173 |
80 | MP0000569_abnormal_digit_pigmentation | 0.69885517 |
81 | MP0003950_abnormal_plasma_membrane | 0.69389814 |
82 | MP0003303_peritoneal_inflammation | 0.67172055 |
83 | MP0004883_abnormal_blood_vessel | 0.66553412 |
84 | MP0003690_abnormal_glial_cell | 0.65690934 |
85 | MP0000313_abnormal_cell_death | 0.65528896 |
86 | MP0008873_increased_physiological_sensi | 0.65012627 |
87 | MP0002877_abnormal_melanocyte_morpholog | 0.64566298 |
88 | MP0003183_abnormal_peptide_metabolism | 0.64545540 |
89 | MP0009379_abnormal_foot_pigmentation | 0.62781570 |
90 | MP0000920_abnormal_myelination | 0.62288162 |
91 | MP0001663_abnormal_digestive_system | 0.61222346 |
92 | MP0000477_abnormal_intestine_morphology | 0.60655802 |
93 | MP0003806_abnormal_nucleotide_metabolis | 0.60482137 |
94 | MP0005166_decreased_susceptibility_to | 0.58797651 |
95 | MP0005379_endocrine/exocrine_gland_phen | 0.57813239 |
96 | MP0004145_abnormal_muscle_electrophysio | 0.57113198 |
97 | MP0009764_decreased_sensitivity_to | 0.55905402 |
98 | MP0005377_hearing/vestibular/ear_phenot | 0.54542798 |
99 | MP0003878_abnormal_ear_physiology | 0.54542798 |
100 | MP0000343_altered_response_to | 0.53629584 |
101 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.53042664 |
102 | MP0005390_skeleton_phenotype | 0.52633251 |
103 | MP0005310_abnormal_salivary_gland | 0.50849077 |
104 | MP0001919_abnormal_reproductive_system | 0.49961043 |
105 | MP0005645_abnormal_hypothalamus_physiol | 0.49543948 |
106 | MP0001191_abnormal_skin_condition | 0.49386664 |
107 | MP0001905_abnormal_dopamine_level | 0.48484241 |
108 | MP0005164_abnormal_response_to | 0.48306867 |
109 | MP0001765_abnormal_ion_homeostasis | 0.48143075 |
110 | MP0009765_abnormal_xenobiotic_induced | 0.47963780 |
111 | MP0002083_premature_death | 0.46749414 |
112 | MP0005319_abnormal_enzyme/_coenzyme | 0.46130290 |
113 | MP0005058_abnormal_lysosome_morphology | 0.45941057 |
114 | MP0002136_abnormal_kidney_physiology | 0.45707586 |
115 | MP0000249_abnormal_blood_vessel | 0.45357978 |
116 | MP0001764_abnormal_homeostasis | 0.44154259 |
117 | MP0002876_abnormal_thyroid_physiology | 0.43931561 |
118 | MP0000371_diluted_coat_color | 0.43914304 |
119 | MP0003186_abnormal_redox_activity | 0.43823551 |
120 | MP0005023_abnormal_wound_healing | 0.43403825 |
121 | MP0004130_abnormal_muscle_cell | 0.42880307 |
122 | MP0009643_abnormal_urine_homeostasis | 0.42658283 |
123 | MP0005409_darkened_coat_color | 0.42346354 |
124 | MP0001501_abnormal_sleep_pattern | 0.42206111 |
125 | MP0008932_abnormal_embryonic_tissue | 0.41707146 |
126 | MP0005083_abnormal_biliary_tract | 0.41628373 |
127 | MP0003943_abnormal_hepatobiliary_system | 0.41461969 |
128 | MP0000613_abnormal_salivary_gland | 0.41406917 |
129 | MP0003795_abnormal_bone_structure | 0.41356938 |
130 | MP0008961_abnormal_basal_metabolism | 0.40814513 |
131 | MP0005670_abnormal_white_adipose | 0.39036400 |
132 | MP0000604_amyloidosis | 0.38216228 |
133 | MP0005451_abnormal_body_composition | 0.38046242 |
Rank | Gene Set | Z-score |
---|---|---|
1 | T lymphocytopenia (HP:0005403) | 5.42407362 |
2 | Abnormality of T cell number (HP:0011839) | 5.21019648 |
3 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.86697310 |
4 | Thrombocytosis (HP:0001894) | 4.63449788 |
5 | Severe combined immunodeficiency (HP:0004430) | 4.60277834 |
6 | Myositis (HP:0100614) | 4.47976223 |
7 | Combined immunodeficiency (HP:0005387) | 4.28566492 |
8 | Abnormality of T cells (HP:0002843) | 4.11810372 |
9 | Recurrent abscess formation (HP:0002722) | 3.98252997 |
10 | Autoimmune hemolytic anemia (HP:0001890) | 3.97213613 |
11 | Abnormality of the prostate (HP:0008775) | 3.93187059 |
12 | Hypoplasia of the thymus (HP:0000778) | 3.89682949 |
13 | Stomatitis (HP:0010280) | 3.86991275 |
14 | Chronic obstructive pulmonary disease (HP:0006510) | 3.79248536 |
15 | Obstructive lung disease (HP:0006536) | 3.79248536 |
16 | Recurrent bronchitis (HP:0002837) | 3.76020137 |
17 | IgG deficiency (HP:0004315) | 3.66567992 |
18 | Aplastic anemia (HP:0001915) | 3.66556103 |
19 | Abnormality of eosinophils (HP:0001879) | 3.60262804 |
20 | Chronic otitis media (HP:0000389) | 3.58775570 |
21 | Abnormal number of erythroid precursors (HP:0012131) | 3.51781335 |
22 | Nasal polyposis (HP:0100582) | 3.50742052 |
23 | IgM deficiency (HP:0002850) | 3.50500153 |
24 | Meningitis (HP:0001287) | 3.48102977 |
25 | Pustule (HP:0200039) | 3.36199262 |
26 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.29331172 |
27 | Eczematoid dermatitis (HP:0000976) | 3.27608022 |
28 | Autoimmune thrombocytopenia (HP:0001973) | 3.26758317 |
29 | Orchitis (HP:0100796) | 3.26480274 |
30 | Retrobulbar optic neuritis (HP:0100654) | 3.26140696 |
31 | Optic neuritis (HP:0100653) | 3.26140696 |
32 | Lymphopenia (HP:0001888) | 3.25474254 |
33 | Leukocytosis (HP:0001974) | 3.22443315 |
34 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 3.19990757 |
35 | Eosinophilia (HP:0001880) | 3.15811860 |
36 | Type I transferrin isoform profile (HP:0003642) | 3.13947923 |
37 | Hemiplegia (HP:0002301) | 3.08441214 |
38 | Thyroiditis (HP:0100646) | 3.03037126 |
39 | Petechiae (HP:0000967) | 2.99910609 |
40 | Encephalitis (HP:0002383) | 2.97249304 |
41 | Granulocytopenia (HP:0001913) | 2.93955994 |
42 | Recurrent fungal infections (HP:0002841) | 2.93823241 |
43 | Pulmonary infiltrates (HP:0002113) | 2.90291855 |
44 | Gastrointestinal infarctions (HP:0005244) | 2.89039810 |
45 | Abnormality of T cell physiology (HP:0011840) | 2.88632122 |
46 | Increased IgM level (HP:0003496) | 2.87365100 |
47 | Mediastinal lymphadenopathy (HP:0100721) | 2.85758780 |
48 | Hemoptysis (HP:0002105) | 2.85751661 |
49 | Recurrent bacterial skin infections (HP:0005406) | 2.84017901 |
50 | Hypergammaglobulinemia (HP:0010702) | 2.83642044 |
51 | Abnormality of the nasal mucosa (HP:0000433) | 2.82119085 |
52 | Gangrene (HP:0100758) | 2.80586435 |
53 | Reduced antithrombin III activity (HP:0001976) | 2.80210194 |
54 | Keratoconjunctivitis sicca (HP:0001097) | 2.79598127 |
55 | Ureteral stenosis (HP:0000071) | 2.77659410 |
56 | Acute hepatic failure (HP:0006554) | 2.72276322 |
57 | Recurrent viral infections (HP:0004429) | 2.69095919 |
58 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.66771293 |
59 | Panhypogammaglobulinemia (HP:0003139) | 2.64368039 |
60 | Chronic diarrhea (HP:0002028) | 2.59554506 |
61 | Chest pain (HP:0100749) | 2.58672237 |
62 | Reticulocytopenia (HP:0001896) | 2.58029008 |
63 | Renal cortical cysts (HP:0000803) | 2.57766347 |
64 | Lymphoma (HP:0002665) | 2.56578359 |
65 | Abnormal protein glycosylation (HP:0012346) | 2.56087964 |
66 | Abnormal glycosylation (HP:0012345) | 2.56087964 |
67 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.56087964 |
68 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.56087964 |
69 | Pulmonary fibrosis (HP:0002206) | 2.55782663 |
70 | Joint swelling (HP:0001386) | 2.55710159 |
71 | Periodontitis (HP:0000704) | 2.55143940 |
72 | Vasculitis (HP:0002633) | 2.53837498 |
73 | Keratoconjunctivitis (HP:0001096) | 2.51621513 |
74 | Epistaxis (HP:0000421) | 2.51352426 |
75 | Recurrent cutaneous fungal infections (HP:0011370) | 2.50926118 |
76 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.50926118 |
77 | Hypochromic anemia (HP:0001931) | 2.44379750 |
78 | Ureteral obstruction (HP:0006000) | 2.42802004 |
79 | Premature graying of hair (HP:0002216) | 2.41754820 |
80 | Abnormality of the pleura (HP:0002103) | 2.38482462 |
81 | Poikiloderma (HP:0001029) | 2.37618945 |
82 | Hypoproteinemia (HP:0003075) | 2.37572634 |
83 | Muscle fiber atrophy (HP:0100295) | 2.34871775 |
84 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.28741263 |
85 | Recurrent skin infections (HP:0001581) | 2.28536161 |
86 | Type 2 muscle fiber atrophy (HP:0003554) | 2.27678494 |
87 | Episodic fever (HP:0001954) | 2.27169902 |
88 | Increased serum ferritin (HP:0003281) | 2.26225532 |
89 | Prolonged bleeding time (HP:0003010) | 2.23443741 |
90 | Abnormality of macrophages (HP:0004311) | 2.23169961 |
91 | Anorexia (HP:0002039) | 2.21940226 |
92 | Abnormal albumin level (HP:0012116) | 2.20517113 |
93 | Hypoalbuminemia (HP:0003073) | 2.20517113 |
94 | Amaurosis fugax (HP:0100576) | 2.18856179 |
95 | 11 pairs of ribs (HP:0000878) | 2.18124807 |
96 | Pulmonary embolism (HP:0002204) | 2.17691448 |
97 | Abnormality of B cell number (HP:0010975) | 2.17417086 |
98 | B lymphocytopenia (HP:0010976) | 2.17417086 |
99 | Oral leukoplakia (HP:0002745) | 2.14014834 |
100 | Recurrent otitis media (HP:0000403) | 2.11765465 |
101 | Pancytopenia (HP:0001876) | 2.11461064 |
102 | Urticaria (HP:0001025) | 2.11135701 |
103 | Glomerulopathy (HP:0100820) | 2.10777549 |
104 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 2.09406456 |
105 | Recurrent sinusitis (HP:0011108) | 2.08343806 |
106 | Agammaglobulinemia (HP:0004432) | 2.08260068 |
107 | Vacuolated lymphocytes (HP:0001922) | 2.07933859 |
108 | Neutropenia (HP:0001875) | 2.06282912 |
109 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.04265263 |
110 | Increased IgE level (HP:0003212) | 2.03813830 |
111 | Inflammation of the large intestine (HP:0002037) | 2.02614543 |
112 | Bronchitis (HP:0012387) | 2.02162099 |
113 | Polyneuropathy (HP:0001271) | 2.01772182 |
114 | Arterial thrombosis (HP:0004420) | 2.01624400 |
115 | Entropion (HP:0000621) | 2.01413377 |
116 | Gingivitis (HP:0000230) | 2.00714761 |
117 | Keratitis (HP:0000491) | 1.99094490 |
118 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.96045893 |
119 | Alveolar cell carcinoma (HP:0006519) | 1.95325780 |
120 | Spontaneous hematomas (HP:0007420) | 1.94969234 |
121 | Skin rash (HP:0000988) | 1.93451709 |
122 | 3-Methylglutaconic aciduria (HP:0003535) | 1.92943298 |
123 | Abnormality of the pericardium (HP:0001697) | 1.92095309 |
124 | Abnormality of iron homeostasis (HP:0011031) | 1.89463234 |
125 | Gastrointestinal inflammation (HP:0004386) | 1.86713647 |
126 | Acne (HP:0001061) | 1.71303725 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TXK | 5.56556579 |
2 | MAP4K1 | 4.01729866 |
3 | TESK2 | 3.36393993 |
4 | MAP3K12 | 3.00985066 |
5 | KDR | 2.89353938 |
6 | ITK | 2.73886344 |
7 | ZAP70 | 2.60711519 |
8 | RIPK4 | 2.53025902 |
9 | STK16 | 2.45964037 |
10 | EIF2AK3 | 2.42324312 |
11 | IRAK4 | 2.16733680 |
12 | TEC | 2.13444692 |
13 | JAK3 | 2.10334235 |
14 | NME2 | 1.95447125 |
15 | BTK | 1.91666182 |
16 | EIF2AK1 | 1.85881989 |
17 | BLK | 1.77070721 |
18 | BUB1 | 1.75312438 |
19 | CDC7 | 1.71275097 |
20 | LCK | 1.70512002 |
21 | CLK1 | 1.66880676 |
22 | MAP3K14 | 1.66062075 |
23 | ACVR1B | 1.62036070 |
24 | TYK2 | 1.55030491 |
25 | JAK1 | 1.52164581 |
26 | SYK | 1.52093691 |
27 | STK10 | 1.52039405 |
28 | VRK1 | 1.48344064 |
29 | MST4 | 1.46509275 |
30 | PIM2 | 1.44475927 |
31 | IKBKE | 1.42238122 |
32 | KIT | 1.38827706 |
33 | CSK | 1.37659700 |
34 | BCKDK | 1.37538149 |
35 | BMPR2 | 1.24889705 |
36 | TBK1 | 1.22298644 |
37 | FES | 1.21258286 |
38 | GRK6 | 1.18409440 |
39 | TESK1 | 1.16857581 |
40 | MAP2K6 | 1.14291381 |
41 | WEE1 | 1.12423520 |
42 | TLK1 | 1.10292714 |
43 | LYN | 1.10253664 |
44 | MARK3 | 1.07235848 |
45 | PIK3CA | 1.06068224 |
46 | CDK8 | 1.00241498 |
47 | MYLK | 0.99671207 |
48 | PIM1 | 0.97404954 |
49 | NLK | 0.88938878 |
50 | SRPK1 | 0.88879902 |
51 | TYRO3 | 0.87345794 |
52 | PRKCH | 0.86150670 |
53 | TNK2 | 0.83571699 |
54 | HCK | 0.83296152 |
55 | JAK2 | 0.82349019 |
56 | TGFBR2 | 0.81992730 |
57 | TAOK3 | 0.81232545 |
58 | ATR | 0.80833998 |
59 | DAPK1 | 0.79980460 |
60 | TNIK | 0.79361856 |
61 | CDK4 | 0.78539644 |
62 | NEK9 | 0.75181570 |
63 | EEF2K | 0.75163680 |
64 | TSSK6 | 0.74982624 |
65 | LRRK2 | 0.74934525 |
66 | PLK4 | 0.73636587 |
67 | TAOK1 | 0.73076022 |
68 | EIF2AK2 | 0.72740264 |
69 | PRKCQ | 0.72673576 |
70 | PRPF4B | 0.72633201 |
71 | PDK1 | 0.71299205 |
72 | ILK | 0.71256825 |
73 | WNK4 | 0.69916109 |
74 | CAMKK2 | 0.69875215 |
75 | SIK3 | 0.68044782 |
76 | MAP3K3 | 0.67944448 |
77 | FLT3 | 0.67019027 |
78 | NEK2 | 0.65542113 |
79 | ZAK | 0.64655275 |
80 | IKBKB | 0.62879032 |
81 | RAF1 | 0.62869890 |
82 | MATK | 0.62690402 |
83 | ERN1 | 0.61663665 |
84 | CDK7 | 0.60932360 |
85 | AURKB | 0.60816830 |
86 | MAPKAPK3 | 0.60702638 |
87 | BRSK1 | 0.60267368 |
88 | SCYL2 | 0.59791859 |
89 | RPS6KA4 | 0.59050859 |
90 | CDK3 | 0.58775632 |
91 | CSF1R | 0.58136620 |
92 | FGR | 0.57715622 |
93 | MAP3K13 | 0.55653016 |
94 | RPS6KB2 | 0.55307578 |
95 | EPHB1 | 0.54728813 |
96 | PIK3CG | 0.52637825 |
97 | TAOK2 | 0.49660379 |
98 | STK4 | 0.48526701 |
99 | PAK4 | 0.47730024 |
100 | ADRBK2 | 0.47216937 |
101 | MAP2K3 | 0.46303405 |
102 | GRK7 | 0.44327557 |
103 | BRSK2 | 0.44186050 |
104 | INSR | 0.43628974 |
105 | PASK | 0.43512352 |
106 | PRKCD | 0.42378453 |
107 | MAP3K11 | 0.40630307 |
108 | RPS6KA6 | 0.40312838 |
109 | MAPKAPK2 | 0.40157571 |
110 | MAP3K5 | 0.39975085 |
111 | PLK1 | 0.38843773 |
112 | FYN | 0.38707124 |
113 | GRK5 | 0.36946819 |
114 | MAPK4 | 0.35221328 |
115 | RPS6KC1 | 0.35099973 |
116 | RPS6KL1 | 0.35099973 |
117 | CAMKK1 | 0.34557297 |
118 | MAPK11 | 0.32698562 |
119 | GRK1 | 0.31736407 |
120 | CDK9 | 0.30460208 |
121 | FGFR4 | 0.30347948 |
122 | IGF1R | 0.29089350 |
123 | LIMK1 | 0.28888175 |
124 | PDGFRB | 0.28719257 |
125 | AURKA | 0.28044132 |
126 | NUAK1 | 0.26765063 |
127 | RPS6KB1 | 0.26453391 |
128 | MAP3K8 | 0.26154381 |
129 | VRK2 | 0.25754319 |
130 | CSNK2A1 | 0.25396241 |
131 | CSNK2A2 | 0.24972400 |
132 | PTK2B | 0.24341298 |
133 | MUSK | 0.24316543 |
134 | OXSR1 | 0.24284162 |
135 | ADRBK1 | 0.23763455 |
136 | PRKCA | 0.22574729 |
137 | STK11 | 0.22261363 |
138 | ABL1 | 0.22258486 |
139 | MAPK12 | 0.22082404 |
140 | HIPK2 | 0.18165386 |
141 | FRK | 0.17221452 |
142 | MAP3K1 | 0.15735588 |
143 | SRC | 0.15143375 |
144 | MAP3K7 | 0.15042751 |
145 | PRKD2 | 0.12827125 |
146 | PRKCB | 0.12707285 |
147 | PAK1 | 0.12500839 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Graft-versus-host disease_Homo sapiens_hsa05332 | 5.81244692 |
2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.30667694 |
3 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 4.03448970 |
4 | Antigen processing and presentation_Homo sapiens_hsa04612 | 3.76568608 |
5 | DNA replication_Homo sapiens_hsa03030 | 3.66977555 |
6 | Ribosome_Homo sapiens_hsa03010 | 2.75017008 |
7 | Mismatch repair_Homo sapiens_hsa03430 | 2.60877423 |
8 | Allograft rejection_Homo sapiens_hsa05330 | 2.56327589 |
9 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.18328366 |
10 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 2.12395583 |
11 | Measles_Homo sapiens_hsa05162 | 2.09356566 |
12 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.92831519 |
13 | Proteasome_Homo sapiens_hsa03050 | 1.90837686 |
14 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.89623547 |
15 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.89117687 |
16 | Protein export_Homo sapiens_hsa03060 | 1.86858725 |
17 | Base excision repair_Homo sapiens_hsa03410 | 1.83060444 |
18 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.80872018 |
19 | Homologous recombination_Homo sapiens_hsa03440 | 1.75969413 |
20 | Leishmaniasis_Homo sapiens_hsa05140 | 1.56448866 |
21 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.51777976 |
22 | RNA polymerase_Homo sapiens_hsa03020 | 1.51191279 |
23 | Viral myocarditis_Homo sapiens_hsa05416 | 1.50855720 |
24 | Spliceosome_Homo sapiens_hsa03040 | 1.46105391 |
25 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.43230618 |
26 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.36294882 |
27 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.31488613 |
28 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.27710419 |
29 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.26854569 |
30 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.25403937 |
31 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.19748985 |
32 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.15532795 |
33 | Other glycan degradation_Homo sapiens_hsa00511 | 1.12854261 |
34 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.12106325 |
35 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.07822334 |
36 | RNA degradation_Homo sapiens_hsa03018 | 1.02661902 |
37 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.97113646 |
38 | Cell cycle_Homo sapiens_hsa04110 | 0.95512719 |
39 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.95366543 |
40 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.94508450 |
41 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.94396805 |
42 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.93987768 |
43 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.93805213 |
44 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.93771618 |
45 | Apoptosis_Homo sapiens_hsa04210 | 0.93587239 |
46 | Malaria_Homo sapiens_hsa05144 | 0.92426172 |
47 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.88549655 |
48 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.85457611 |
49 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.79940017 |
50 | Shigellosis_Homo sapiens_hsa05131 | 0.79733541 |
51 | Asthma_Homo sapiens_hsa05310 | 0.78078758 |
52 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.76645829 |
53 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.76245737 |
54 | Basal transcription factors_Homo sapiens_hsa03022 | 0.75858204 |
55 | HTLV-I infection_Homo sapiens_hsa05166 | 0.74004691 |
56 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.70908979 |
57 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.69918656 |
58 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.69257326 |
59 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.68078477 |
60 | RNA transport_Homo sapiens_hsa03013 | 0.67452750 |
61 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.66840781 |
62 | Legionellosis_Homo sapiens_hsa05134 | 0.64868676 |
63 | Purine metabolism_Homo sapiens_hsa00230 | 0.61361230 |
64 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.61136456 |
65 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.60599678 |
66 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.58936691 |
67 | Hepatitis B_Homo sapiens_hsa05161 | 0.57798805 |
68 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.57779503 |
69 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.56663593 |
70 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.54361358 |
71 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.51690812 |
72 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.51430610 |
73 | Influenza A_Homo sapiens_hsa05164 | 0.51304028 |
74 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.51003762 |
75 | Platelet activation_Homo sapiens_hsa04611 | 0.50582164 |
76 | Phagosome_Homo sapiens_hsa04145 | 0.50570973 |
77 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.50491321 |
78 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.50090887 |
79 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.49621964 |
80 | Pertussis_Homo sapiens_hsa05133 | 0.49446115 |
81 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.48887926 |
82 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.48474886 |
83 | Endocytosis_Homo sapiens_hsa04144 | 0.47883592 |
84 | Prion diseases_Homo sapiens_hsa05020 | 0.47807931 |
85 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.47763113 |
86 | Salmonella infection_Homo sapiens_hsa05132 | 0.47590637 |
87 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.44974966 |
88 | Galactose metabolism_Homo sapiens_hsa00052 | 0.44381537 |
89 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.43710117 |
90 | Phototransduction_Homo sapiens_hsa04744 | 0.42656899 |
91 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.41480550 |
92 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.37955969 |
93 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.36040518 |
94 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.35417796 |
95 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.33960386 |
96 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.33410690 |
97 | Tuberculosis_Homo sapiens_hsa05152 | 0.32166110 |
98 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.32051907 |
99 | Lysosome_Homo sapiens_hsa04142 | 0.31065509 |
100 | Colorectal cancer_Homo sapiens_hsa05210 | 0.30874226 |
101 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.29874451 |
102 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.29127171 |
103 | Alzheimers disease_Homo sapiens_hsa05010 | 0.28502370 |
104 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.28278230 |
105 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.26983051 |
106 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.26732360 |
107 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.25559302 |
108 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.25155185 |
109 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.25118874 |
110 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.24422540 |
111 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.24185972 |
112 | Thyroid cancer_Homo sapiens_hsa05216 | 0.23548964 |
113 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.21976661 |
114 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.21972843 |
115 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.19738655 |
116 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.19674120 |
117 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.19389986 |
118 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.18880215 |
119 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.17030600 |
120 | Sulfur relay system_Homo sapiens_hsa04122 | 0.15698228 |
121 | Parkinsons disease_Homo sapiens_hsa05012 | 0.15415729 |
122 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.15318138 |
123 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.14612845 |
124 | Hepatitis C_Homo sapiens_hsa05160 | 0.14228089 |
125 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.14221042 |
126 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.11474705 |
127 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.09836055 |
128 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.05814379 |
129 | Olfactory transduction_Homo sapiens_hsa04740 | 0.05112538 |
130 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.03304399 |
131 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.02239802 |
132 | Huntingtons disease_Homo sapiens_hsa05016 | 0.01630545 |
133 | Cardiac muscle contraction_Homo sapiens_hsa04260 | -0.0423474 |
134 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | -0.0245697 |
135 | Peroxisome_Homo sapiens_hsa04146 | -0.0243748 |