Rank | Gene Set | Z-score |
---|---|---|
1 | thyroid hormone generation (GO:0006590) | 8.80214361 |
2 | pattern specification involved in kidney development (GO:0061004) | 7.37352192 |
3 | thyroid hormone metabolic process (GO:0042403) | 6.92063170 |
4 | ganglion development (GO:0061548) | 6.69910371 |
5 | neuronal stem cell maintenance (GO:0097150) | 5.50128508 |
6 | spinal cord association neuron differentiation (GO:0021527) | 5.38788443 |
7 | presynaptic membrane organization (GO:0097090) | 5.18881006 |
8 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 5.10003392 |
9 | nephron tubule development (GO:0072080) | 5.06587461 |
10 | sympathetic nervous system development (GO:0048485) | 5.06336569 |
11 | cellular response to nitric oxide (GO:0071732) | 5.03607927 |
12 | regulation of development, heterochronic (GO:0040034) | 4.67983446 |
13 | left/right axis specification (GO:0070986) | 4.60370869 |
14 | negative regulation of oligodendrocyte differentiation (GO:0048715) | 4.51202987 |
15 | * neuron fate commitment (GO:0048663) | 4.50800731 |
16 | lung lobe morphogenesis (GO:0060463) | 4.48923484 |
17 | renal tubule development (GO:0061326) | 4.45563453 |
18 | regulation of timing of cell differentiation (GO:0048505) | 4.34183876 |
19 | * lung secretory cell differentiation (GO:0061140) | 4.32226867 |
20 | sodium-independent organic anion transport (GO:0043252) | 4.31552225 |
21 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 4.31427680 |
22 | sulfate transmembrane transport (GO:1902358) | 4.23082376 |
23 | response to xenobiotic stimulus (GO:0009410) | 4.20224393 |
24 | regulation of response to osmotic stress (GO:0047484) | 4.15934309 |
25 | regulation of phospholipid biosynthetic process (GO:0071071) | 4.01023494 |
26 | nephron epithelium development (GO:0072009) | 3.98937825 |
27 | regulation of sarcomere organization (GO:0060297) | 3.98010725 |
28 | respiratory gaseous exchange (GO:0007585) | 3.93744737 |
29 | pyrimidine nucleobase catabolic process (GO:0006208) | 3.92966594 |
30 | regulation of hippo signaling (GO:0035330) | 3.92017973 |
31 | reflex (GO:0060004) | 3.91525728 |
32 | positive regulation of Notch signaling pathway (GO:0045747) | 3.90184733 |
33 | mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337) | 3.88404433 |
34 | cellular response to reactive nitrogen species (GO:1902170) | 3.85443420 |
35 | intraciliary transport (GO:0042073) | 3.83180911 |
36 | positive regulation of endothelial cell differentiation (GO:0045603) | 3.76631174 |
37 | negative regulation of epidermal cell differentiation (GO:0045605) | 3.75089891 |
38 | negative regulation of complement activation (GO:0045916) | 3.69191539 |
39 | semaphorin-plexin signaling pathway (GO:0071526) | 3.67436741 |
40 | one-carbon compound transport (GO:0019755) | 3.63895846 |
41 | musculoskeletal movement (GO:0050881) | 3.61508921 |
42 | multicellular organismal movement (GO:0050879) | 3.61508921 |
43 | limb bud formation (GO:0060174) | 3.59704067 |
44 | response to nitric oxide (GO:0071731) | 3.58770463 |
45 | sulfate transport (GO:0008272) | 3.47427538 |
46 | branch elongation of an epithelium (GO:0060602) | 3.47348733 |
47 | cilium or flagellum-dependent cell motility (GO:0001539) | 3.46515393 |
48 | response to folic acid (GO:0051593) | 3.46094276 |
49 | presynaptic membrane assembly (GO:0097105) | 3.40318206 |
50 | regulation of oligodendrocyte differentiation (GO:0048713) | 3.40150150 |
51 | * thyroid gland development (GO:0030878) | 3.38514934 |
52 | * forebrain neuron differentiation (GO:0021879) | 3.38389623 |
53 | negative regulation of mesenchymal cell apoptotic process (GO:2001054) | 3.32057663 |
54 | neuroblast proliferation (GO:0007405) | 3.31151455 |
55 | postsynaptic membrane organization (GO:0001941) | 3.30702517 |
56 | neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976) | 3.30630214 |
57 | negative regulation of interleukin-10 production (GO:0032693) | 3.26911144 |
58 | olfactory bulb development (GO:0021772) | 3.26780681 |
59 | metanephric nephron tubule development (GO:0072234) | 3.19426818 |
60 | metanephric tubule development (GO:0072170) | 3.19426818 |
61 | sodium ion homeostasis (GO:0055078) | 3.18796199 |
62 | negative regulation of protein activation cascade (GO:2000258) | 3.16486206 |
63 | * cerebral cortex neuron differentiation (GO:0021895) | 3.16455497 |
64 | mesodermal cell differentiation (GO:0048333) | 3.15392798 |
65 | neural tube formation (GO:0001841) | 3.12536417 |
66 | regulation of endothelial cell differentiation (GO:0045601) | 3.12360613 |
67 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 3.10549222 |
68 | positive regulation of oligodendrocyte differentiation (GO:0048714) | 3.10514601 |
69 | bicarbonate transport (GO:0015701) | 3.10258885 |
70 | branching involved in labyrinthine layer morphogenesis (GO:0060670) | 3.10179385 |
71 | vocalization behavior (GO:0071625) | 3.08783752 |
72 | negative regulation of transcription by competitive promoter binding (GO:0010944) | 3.08158691 |
73 | cell differentiation in spinal cord (GO:0021515) | 3.07976692 |
74 | glomerular epithelial cell development (GO:0072310) | 3.07106104 |
75 | polyol transport (GO:0015791) | 3.04824944 |
76 | endocardial cushion development (GO:0003197) | 3.02612445 |
77 | negative regulation of humoral immune response (GO:0002921) | 3.01586725 |
78 | lung vasculature development (GO:0060426) | 3.01400228 |
79 | cellular anion homeostasis (GO:0030002) | 3.00691445 |
80 | lateral sprouting from an epithelium (GO:0060601) | 3.00381161 |
81 | somite development (GO:0061053) | 2.99452595 |
82 | response to parathyroid hormone (GO:0071107) | 2.99059253 |
83 | regulation of glomerular filtration (GO:0003093) | 2.96788935 |
84 | respiratory tube development (GO:0030323) | 2.95944991 |
85 | lung epithelium development (GO:0060428) | 2.94177290 |
86 | cornea development in camera-type eye (GO:0061303) | 2.92845537 |
87 | hemidesmosome assembly (GO:0031581) | 2.92328726 |
88 | neuronal ion channel clustering (GO:0045161) | 2.91028591 |
89 | nucleobase catabolic process (GO:0046113) | 2.90498125 |
90 | regulation of branching involved in prostate gland morphogenesis (GO:0060687) | 2.89085064 |
91 | axis elongation (GO:0003401) | 2.88007211 |
92 | glomerular visceral epithelial cell development (GO:0072015) | 2.87462687 |
93 | glycosphingolipid biosynthetic process (GO:0006688) | 2.87322359 |
94 | segment specification (GO:0007379) | 2.86921016 |
95 | morphogenesis of an endothelium (GO:0003159) | 2.84535268 |
96 | endothelial tube morphogenesis (GO:0061154) | 2.84535268 |
97 | synapse assembly (GO:0007416) | 2.82964980 |
98 | lymphangiogenesis (GO:0001946) | 2.82519894 |
99 | axonal fasciculation (GO:0007413) | 2.81506851 |
100 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 2.80781850 |
101 | facial nerve structural organization (GO:0021612) | 2.80688288 |
102 | metanephric nephron epithelium development (GO:0072243) | 2.80603915 |
103 | gamma-aminobutyric acid transport (GO:0015812) | 2.79873666 |
104 | ectodermal placode formation (GO:0060788) | 2.79770335 |
105 | lung alveolus development (GO:0048286) | 2.78647499 |
106 | hypothalamus development (GO:0021854) | 2.78543418 |
107 | sequestering of actin monomers (GO:0042989) | 2.78409326 |
108 | protein localization to cilium (GO:0061512) | 2.77504319 |
109 | fibroblast migration (GO:0010761) | 2.76758115 |
110 | phosphate ion homeostasis (GO:0055062) | 2.75756913 |
111 | trivalent inorganic anion homeostasis (GO:0072506) | 2.75756913 |
112 | negative regulation of interleukin-2 production (GO:0032703) | 2.75544799 |
113 | regulation of interleukin-13 production (GO:0032656) | 2.75491264 |
114 | lens morphogenesis in camera-type eye (GO:0002089) | 2.74688539 |
115 | response to vitamin A (GO:0033189) | 2.73345207 |
116 | neuron recognition (GO:0008038) | 2.72621428 |
117 | cardiac ventricle formation (GO:0003211) | 2.70055402 |
118 | axonemal dynein complex assembly (GO:0070286) | 2.69847958 |
119 | cell fate determination (GO:0001709) | 2.69155350 |
120 | glial cell proliferation (GO:0014009) | 2.69097509 |
121 | nephron tubule formation (GO:0072079) | 2.68391046 |
122 | response to increased oxygen levels (GO:0036296) | 2.67983148 |
123 | response to hyperoxia (GO:0055093) | 2.67983148 |
124 | regulation of transcription involved in cell fate commitment (GO:0060850) | 2.67827183 |
125 | negative regulation of epidermis development (GO:0045683) | 2.67809704 |
126 | branching involved in salivary gland morphogenesis (GO:0060445) | 2.64451710 |
127 | regulation of axon extension involved in axon guidance (GO:0048841) | 2.64336043 |
128 | metanephric epithelium development (GO:0072207) | 2.63801771 |
129 | DNA double-strand break processing (GO:0000729) | 2.63258700 |
130 | negative regulation of pathway-restricted SMAD protein phosphorylation (GO:0060394) | 2.61430312 |
131 | negative regulation of cell fate specification (GO:0009996) | 2.60472727 |
132 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338) | 2.60450316 |
133 | limb development (GO:0060173) | 2.60315495 |
134 | appendage development (GO:0048736) | 2.60315495 |
135 | axon ensheathment in central nervous system (GO:0032291) | 2.60267329 |
136 | central nervous system myelination (GO:0022010) | 2.60267329 |
137 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 2.59765770 |
138 | substrate-independent telencephalic tangential migration (GO:0021826) | 2.59765770 |
139 | induction of positive chemotaxis (GO:0050930) | 2.59236342 |
140 | * lung cell differentiation (GO:0060479) | 2.56501813 |
141 | regulation of mitochondrial depolarization (GO:0051900) | 2.55820341 |
142 | phosphate ion transmembrane transport (GO:0035435) | 2.55807952 |
143 | regulation of Notch signaling pathway (GO:0008593) | 2.55778105 |
144 | ethanol oxidation (GO:0006069) | 2.54361290 |
145 | regulation of interleukin-5 production (GO:0032674) | 2.51880495 |
146 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:004316 | 2.50543851 |
147 | cilium movement (GO:0003341) | 2.50317221 |
148 | epithelial cilium movement (GO:0003351) | 2.48817254 |
149 | mitochondrion distribution (GO:0048311) | 2.48137625 |
150 | * epithelial tube branching involved in lung morphogenesis (GO:0060441) | 2.47495458 |
151 | eye photoreceptor cell differentiation (GO:0001754) | 2.46553290 |
152 | photoreceptor cell differentiation (GO:0046530) | 2.46553290 |
153 | renal system process involved in regulation of blood volume (GO:0001977) | 2.43670415 |
154 | tight junction assembly (GO:0070830) | 2.42594375 |
155 | lung-associated mesenchyme development (GO:0060484) | 2.42539823 |
156 | epithelial cell differentiation involved in prostate gland development (GO:0060742) | 2.41538306 |
157 | negative regulation of catenin import into nucleus (GO:0035414) | 2.40398804 |
158 | mesenchymal cell proliferation (GO:0010463) | 2.40247341 |
159 | embryonic foregut morphogenesis (GO:0048617) | 2.39256047 |
160 | phosphate ion transport (GO:0006817) | 2.37601123 |
161 | regulation of vasculogenesis (GO:2001212) | 2.37065565 |
162 | membrane repolarization during action potential (GO:0086011) | 2.36417315 |
163 | regulation of axon guidance (GO:1902667) | 2.36001939 |
164 | positive regulation of synapse assembly (GO:0051965) | 2.33838103 |
165 | adhesion of symbiont to host cell (GO:0044650) | 2.29776795 |
166 | virion attachment to host cell (GO:0019062) | 2.29776795 |
167 | macrophage chemotaxis (GO:0048246) | 2.26744385 |
168 | establishment of apical/basal cell polarity (GO:0035089) | 2.25459591 |
169 | cranial nerve structural organization (GO:0021604) | 2.25357354 |
170 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800) | 2.24512649 |
171 | outflow tract septum morphogenesis (GO:0003148) | 2.23640736 |
172 | mating behavior (GO:0007617) | 2.23449341 |
173 | negative regulation of alcohol biosynthetic process (GO:1902931) | 2.22990072 |
174 | surfactant homeostasis (GO:0043129) | 15.1838337 |
175 | chemical homeostasis within a tissue (GO:0048875) | 12.5334723 |
Rank | Gene Set | Z-score |
---|---|---|
1 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 3.63672199 |
2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.60116297 |
3 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.55495002 |
4 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.87977000 |
5 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.77328397 |
6 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.72942035 |
7 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.62411757 |
8 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.54992094 |
9 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.52690677 |
10 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.51640080 |
11 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.49822080 |
12 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.43920833 |
13 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.43920833 |
14 | * JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.40915529 |
15 | * JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.37477903 |
16 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.27715380 |
17 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.26237700 |
18 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.23172616 |
19 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.22919361 |
20 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.18936198 |
21 | * EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.17306663 |
22 | * RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.15200612 |
23 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 2.10577998 |
24 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.08453389 |
25 | * MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.08352672 |
26 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 2.03578756 |
27 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.99683174 |
28 | * SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.99197577 |
29 | VDR_22108803_ChIP-Seq_LS180_Human | 1.97958761 |
30 | FUS_26573619_Chip-Seq_HEK293_Human | 1.96513316 |
31 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.92834116 |
32 | * BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.90414016 |
33 | * EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.90094976 |
34 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.88087433 |
35 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.87583645 |
36 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.87418843 |
37 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.82997791 |
38 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.82142750 |
39 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.81578323 |
40 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.75537030 |
41 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.74146070 |
42 | P300_19829295_ChIP-Seq_ESCs_Human | 1.72326773 |
43 | * CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.70530446 |
44 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.69834481 |
45 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.68201858 |
46 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.65206197 |
47 | EWS_26573619_Chip-Seq_HEK293_Human | 1.64303354 |
48 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.57701192 |
49 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.54797874 |
50 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.51494470 |
51 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.49726296 |
52 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.47730626 |
53 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.45846977 |
54 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.44895960 |
55 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.43734467 |
56 | AR_25329375_ChIP-Seq_VCAP_Human | 1.42694206 |
57 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.42087130 |
58 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.41393022 |
59 | STAT3_23295773_ChIP-Seq_U87_Human | 1.39956847 |
60 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.39875430 |
61 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.39197545 |
62 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.39197545 |
63 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.39073708 |
64 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.38448537 |
65 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.38392496 |
66 | * RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.38015250 |
67 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.34207325 |
68 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.33749365 |
69 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.33730108 |
70 | * RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.33680364 |
71 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.32714644 |
72 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.30840815 |
73 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.29598004 |
74 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.25229946 |
75 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.23947968 |
76 | KDM2B_26808549_Chip-Seq_K562_Human | 1.23097374 |
77 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.22918175 |
78 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.22710183 |
79 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.22354577 |
80 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.21425287 |
81 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.19886918 |
82 | * TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.19135022 |
83 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.18669242 |
84 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.18368593 |
85 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.17221754 |
86 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.15773762 |
87 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.15744362 |
88 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.14468707 |
89 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.13225193 |
90 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.11715511 |
91 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 1.10367897 |
92 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.10210333 |
93 | TCF4_23295773_ChIP-Seq_U87_Human | 1.09475854 |
94 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.07997938 |
95 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.07922743 |
96 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.07892502 |
97 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.07838257 |
98 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.07529806 |
99 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.05768837 |
100 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.05174709 |
101 | SOX2_20726797_ChIP-Seq_SW620_Human | 1.05045810 |
102 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.04658914 |
103 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.04580288 |
104 | KLF5_25053715_ChIP-Seq_YYC3_Human | 1.03955518 |
105 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.02484041 |
106 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.01843430 |
107 | JUN_21703547_ChIP-Seq_K562_Human | 1.01727516 |
108 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.00180871 |
109 | * TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.00144359 |
110 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.99888959 |
111 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 0.99631438 |
112 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.97637564 |
113 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.97219659 |
114 | * RNF2_27304074_Chip-Seq_NSC_Mouse | 0.96045897 |
115 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.95832402 |
116 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 0.95283766 |
117 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.95231548 |
118 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.94987422 |
119 | AR_19668381_ChIP-Seq_PC3_Human | 0.94338385 |
120 | * CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 0.94254876 |
121 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.93573198 |
122 | GATA4_25053715_ChIP-Seq_YYC3_Human | 0.93138953 |
123 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.92864033 |
124 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.92799510 |
125 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.92723615 |
126 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.92389683 |
127 | * KDM2B_26808549_Chip-Seq_REH_Human | 0.92029717 |
128 | * FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.91460895 |
129 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 0.91193925 |
130 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.90622525 |
131 | * SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.90582236 |
132 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.90391743 |
133 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.90301231 |
134 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.89861392 |
135 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 0.89690898 |
136 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.89205393 |
137 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.88487114 |
138 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.87226682 |
139 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 0.86639178 |
140 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.85175027 |
141 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.85072731 |
142 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.84982670 |
143 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.84871731 |
144 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 0.84786887 |
145 | CJUN_26792858_Chip-Seq_BT549_Human | 0.84337795 |
146 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.84205741 |
147 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.82544018 |
148 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 0.82263756 |
149 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.82116114 |
150 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 0.80736936 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004782_abnormal_surfactant_physiolog | 8.76611430 |
2 | MP0001958_emphysema | 4.73779880 |
3 | * MP0008995_early_reproductive_senescence | 4.45624179 |
4 | MP0000566_synostosis | 3.88290692 |
5 | MP0008004_abnormal_stomach_pH | 3.87857716 |
6 | MP0008789_abnormal_olfactory_epithelium | 3.69266881 |
7 | MP0001177_atelectasis | 3.36242905 |
8 | MP0005394_taste/olfaction_phenotype | 3.24676737 |
9 | MP0005499_abnormal_olfactory_system | 3.24676737 |
10 | MP0005083_abnormal_biliary_tract | 3.24662545 |
11 | MP0002133_abnormal_respiratory_system | 2.65398951 |
12 | MP0005388_respiratory_system_phenotype | 2.65398951 |
13 | MP0000383_abnormal_hair_follicle | 2.56102462 |
14 | * MP0000681_abnormal_thyroid_gland | 2.46478724 |
15 | MP0002295_abnormal_pulmonary_circulatio | 2.33305518 |
16 | MP0010368_abnormal_lymphatic_system | 2.24521084 |
17 | MP0002234_abnormal_pharynx_morphology | 2.24316288 |
18 | MP0000537_abnormal_urethra_morphology | 2.23479641 |
19 | MP0010678_abnormal_skin_adnexa | 2.20166329 |
20 | MP0003724_increased_susceptibility_to | 2.13603795 |
21 | MP0000462_abnormal_digestive_system | 2.09326692 |
22 | MP0000678_abnormal_parathyroid_gland | 2.01724778 |
23 | MP0003303_peritoneal_inflammation | 1.99785599 |
24 | MP0005646_abnormal_pituitary_gland | 1.90814620 |
25 | MP0001879_abnormal_lymphatic_vessel | 1.85560718 |
26 | MP0000049_abnormal_middle_ear | 1.83034633 |
27 | MP0002138_abnormal_hepatobiliary_system | 1.81802835 |
28 | MP0002102_abnormal_ear_morphology | 1.77495951 |
29 | MP0001440_abnormal_grooming_behavior | 1.71273131 |
30 | MP0002822_catalepsy | 1.66982604 |
31 | MP0004272_abnormal_basement_membrane | 1.65688079 |
32 | MP0003122_maternal_imprinting | 1.61415980 |
33 | MP0005248_abnormal_Harderian_gland | 1.60596885 |
34 | MP0002876_abnormal_thyroid_physiology | 1.56841179 |
35 | MP0005645_abnormal_hypothalamus_physiol | 1.51448851 |
36 | MP0002098_abnormal_vibrissa_morphology | 1.49420988 |
37 | MP0001664_abnormal_digestion | 1.46553025 |
38 | MP0001270_distended_abdomen | 1.46538615 |
39 | MP0006072_abnormal_retinal_apoptosis | 1.42339625 |
40 | MP0005253_abnormal_eye_physiology | 1.41989773 |
41 | MP0001984_abnormal_olfaction | 1.41792042 |
42 | MP0002282_abnormal_trachea_morphology | 1.40405778 |
43 | MP0000534_abnormal_ureter_morphology | 1.36112028 |
44 | MP0000778_abnormal_nervous_system | 1.35367211 |
45 | MP0005623_abnormal_meninges_morphology | 1.28549187 |
46 | MP0005167_abnormal_blood-brain_barrier | 1.27785485 |
47 | MP0000026_abnormal_inner_ear | 1.27772780 |
48 | MP0003890_abnormal_embryonic-extraembry | 1.25942580 |
49 | MP0003880_abnormal_central_pattern | 1.22643809 |
50 | MP0001346_abnormal_lacrimal_gland | 1.20927097 |
51 | MP0003938_abnormal_ear_development | 1.20883651 |
52 | MP0002249_abnormal_larynx_morphology | 1.20380584 |
53 | MP0002108_abnormal_muscle_morphology | 1.15899477 |
54 | MP0010352_gastrointestinal_tract_polyps | 1.15466423 |
55 | MP0003950_abnormal_plasma_membrane | 1.14577940 |
56 | MP0004085_abnormal_heartbeat | 1.12727532 |
57 | MP0002277_abnormal_respiratory_mucosa | 1.12507367 |
58 | * MP0001943_abnormal_respiration | 1.11903039 |
59 | MP0002557_abnormal_social/conspecific_i | 1.11733279 |
60 | * MP0001175_abnormal_lung_morphology | 1.11626940 |
61 | MP0003137_abnormal_impulse_conducting | 1.10582575 |
62 | MP0002733_abnormal_thermal_nociception | 1.07520890 |
63 | MP0003755_abnormal_palate_morphology | 1.05865879 |
64 | MP0005423_abnormal_somatic_nervous | 1.02914890 |
65 | MP0005595_abnormal_vascular_smooth | 0.99980740 |
66 | MP0001188_hyperpigmentation | 0.99726528 |
67 | MP0000733_abnormal_muscle_development | 0.98747608 |
68 | MP0004883_abnormal_blood_vessel | 0.98398423 |
69 | MP0006276_abnormal_autonomic_nervous | 0.94247054 |
70 | * MP0003115_abnormal_respiratory_system | 0.94129418 |
71 | MP0003121_genomic_imprinting | 0.94098743 |
72 | MP0003221_abnormal_cardiomyocyte_apopto | 0.90461767 |
73 | MP0000013_abnormal_adipose_tissue | 0.89938695 |
74 | MP0004742_abnormal_vestibular_system | 0.87872596 |
75 | MP0010030_abnormal_orbit_morphology | 0.87555637 |
76 | MP0002132_abnormal_respiratory_system | 0.86911518 |
77 | MP0005187_abnormal_penis_morphology | 0.85752618 |
78 | MP0009745_abnormal_behavioral_response | 0.85441792 |
79 | MP0004043_abnormal_pH_regulation | 0.83848102 |
80 | MP0002752_abnormal_somatic_nervous | 0.83747640 |
81 | MP0009046_muscle_twitch | 0.83651620 |
82 | MP0003948_abnormal_gas_homeostasis | 0.83081939 |
83 | MP0003942_abnormal_urinary_system | 0.83054327 |
84 | MP0005391_vision/eye_phenotype | 0.78683677 |
85 | MP0001986_abnormal_taste_sensitivity | 0.78006350 |
86 | MP0003635_abnormal_synaptic_transmissio | 0.77889883 |
87 | MP0005164_abnormal_response_to | 0.77844592 |
88 | MP0005409_darkened_coat_color | 0.77622072 |
89 | MP0004885_abnormal_endolymph | 0.77227107 |
90 | MP0000751_myopathy | 0.76472874 |
91 | MP0000762_abnormal_tongue_morphology | 0.76386228 |
92 | MP0000467_abnormal_esophagus_morphology | 0.75485827 |
93 | MP0001299_abnormal_eye_distance/ | 0.75238545 |
94 | MP0009250_abnormal_appendicular_skeleto | 0.75052552 |
95 | MP0003385_abnormal_body_wall | 0.74698587 |
96 | MP0003191_abnormal_cellular_cholesterol | 0.74281754 |
97 | MP0009780_abnormal_chondrocyte_physiolo | 0.74008487 |
98 | MP0000955_abnormal_spinal_cord | 0.73009577 |
99 | * MP0003786_premature_aging | 0.72521953 |
100 | MP0002168_other_aberrant_phenotype | 0.70897022 |
101 | MP0001286_abnormal_eye_development | 0.70829229 |
102 | MP0005381_digestive/alimentary_phenotyp | 0.69215704 |
103 | * MP0002063_abnormal_learning/memory/cond | 0.69029715 |
104 | MP0002882_abnormal_neuron_morphology | 0.68554914 |
105 | MP0002638_abnormal_pupillary_reflex | 0.67852369 |
106 | * MP0004197_abnormal_fetal_growth/weight/ | 0.66701363 |
107 | MP0001968_abnormal_touch/_nociception | 0.64978599 |
108 | * MP0000631_abnormal_neuroendocrine_gland | 0.64520426 |
109 | MP0005195_abnormal_posterior_eye | 0.64060799 |
110 | MP0002735_abnormal_chemical_nociception | 0.63568188 |
111 | MP0008260_abnormal_autophagy | 0.63463535 |
112 | MP0002084_abnormal_developmental_patter | 0.62030119 |
113 | * MP0003119_abnormal_digestive_system | 0.61772924 |
114 | MP0002653_abnormal_ependyma_morphology | 0.61401144 |
115 | MP0001963_abnormal_hearing_physiology | 0.61200565 |
116 | MP0003861_abnormal_nervous_system | 0.61148979 |
117 | MP0002938_white_spotting | 0.60851963 |
118 | MP0005408_hypopigmentation | 0.60750240 |
119 | MP0001340_abnormal_eyelid_morphology | 0.60274746 |
120 | MP0002184_abnormal_innervation | 0.59354627 |
121 | MP0002909_abnormal_adrenal_gland | 0.58495505 |
122 | MP0002751_abnormal_autonomic_nervous | 0.58356232 |
123 | MP0002233_abnormal_nose_morphology | 0.58119346 |
124 | MP0002697_abnormal_eye_size | 0.58064808 |
125 | MP0003935_abnormal_craniofacial_develop | 0.57723059 |
126 | MP0004811_abnormal_neuron_physiology | 0.57561843 |
127 | MP0002069_abnormal_eating/drinking_beha | 0.56619546 |
128 | MP0002925_abnormal_cardiovascular_devel | 0.56504345 |
129 | MP0000627_abnormal_mammary_gland | 0.56261795 |
130 | MP0001502_abnormal_circadian_rhythm | 0.56046814 |
131 | MP0000470_abnormal_stomach_morphology | 0.54067861 |
132 | MP0001970_abnormal_pain_threshold | 0.53815580 |
133 | MP0003937_abnormal_limbs/digits/tail_de | 0.52081720 |
134 | MP0010234_abnormal_vibrissa_follicle | 0.51812199 |
135 | MP0003329_amyloid_beta_deposits | 0.51278850 |
136 | MP0002064_seizures | 0.50457611 |
137 | MP0002796_impaired_skin_barrier | 0.50398736 |
138 | MP0003091_abnormal_cell_migration | 0.50375637 |
139 | MP0008961_abnormal_basal_metabolism | 0.49098072 |
140 | MP0008875_abnormal_xenobiotic_pharmacok | 0.47998796 |
141 | MP0009384_cardiac_valve_regurgitation | 0.47895711 |
142 | MP0000516_abnormal_urinary_system | 0.47117160 |
143 | MP0005367_renal/urinary_system_phenotyp | 0.47117160 |
144 | MP0002332_abnormal_exercise_endurance | 0.46862924 |
145 | MP0004133_heterotaxia | 0.46659814 |
146 | MP0006292_abnormal_olfactory_placode | 0.46516472 |
147 | MP0001501_abnormal_sleep_pattern | 0.46384591 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Hyperactive renin-angiotensin system (HP:0000841) | 6.27947870 |
2 | Tachypnea (HP:0002789) | 5.55243310 |
3 | Tubulointerstitial fibrosis (HP:0005576) | 5.54451917 |
4 | Renal salt wasting (HP:0000127) | 5.05552658 |
5 | Chronic bronchitis (HP:0004469) | 5.01806691 |
6 | Onycholysis (HP:0001806) | 4.90145515 |
7 | Neurofibrillary tangles (HP:0002185) | 4.21635594 |
8 | Fragile nails (HP:0001808) | 4.14830044 |
9 | Tubulointerstitial nephritis (HP:0001970) | 4.12252883 |
10 | * Goiter (HP:0000853) | 3.99461122 |
11 | Stomach cancer (HP:0012126) | 3.99351876 |
12 | Hyperkalemia (HP:0002153) | 3.86508499 |
13 | * Respiratory distress (HP:0002098) | 3.76288856 |
14 | Gout (HP:0001997) | 3.75071035 |
15 | Pili torti (HP:0003777) | 3.67027732 |
16 | Tubulointerstitial abnormality (HP:0001969) | 3.57363520 |
17 | Tetany (HP:0001281) | 3.48343148 |
18 | Split foot (HP:0001839) | 3.41141198 |
19 | Cerebral inclusion bodies (HP:0100314) | 3.39871217 |
20 | Genetic anticipation (HP:0003743) | 3.38486742 |
21 | Hyperaldosteronism (HP:0000859) | 3.31991569 |
22 | Abnormality of the fingertips (HP:0001211) | 3.06939848 |
23 | Abnormality of chloride homeostasis (HP:0011422) | 2.95065227 |
24 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 2.94802128 |
25 | Agitation (HP:0000713) | 2.91257153 |
26 | Buphthalmos (HP:0000557) | 2.89625180 |
27 | Broad metatarsal (HP:0001783) | 2.89496174 |
28 | Hepatoblastoma (HP:0002884) | 2.79410006 |
29 | Sleep apnea (HP:0010535) | 2.79092238 |
30 | Partial duplication of thumb phalanx (HP:0009944) | 2.78551329 |
31 | Tubular atrophy (HP:0000092) | 2.75591745 |
32 | Abnormality of renin-angiotensin system (HP:0000847) | 2.74237823 |
33 | Bronchomalacia (HP:0002780) | 2.72791282 |
34 | Supranuclear gaze palsy (HP:0000605) | 2.67628959 |
35 | Megalencephaly (HP:0001355) | 2.63235385 |
36 | Humeroradial synostosis (HP:0003041) | 2.61034030 |
37 | Synostosis involving the elbow (HP:0003938) | 2.61034030 |
38 | Ulnar bowing (HP:0003031) | 2.59243087 |
39 | Tented upper lip vermilion (HP:0010804) | 2.58742609 |
40 | Thyroid carcinoma (HP:0002890) | 2.53250530 |
41 | Hypothermia (HP:0002045) | 2.50579181 |
42 | Drooling (HP:0002307) | 2.48631674 |
43 | Aplasia involving bones of the extremities (HP:0009825) | 2.47887873 |
44 | Aplasia involving bones of the upper limbs (HP:0009823) | 2.47887873 |
45 | Aplasia of the phalanges of the hand (HP:0009802) | 2.47887873 |
46 | Thickened helices (HP:0000391) | 2.46898158 |
47 | Hyponatremia (HP:0002902) | 2.43804440 |
48 | Visceral angiomatosis (HP:0100761) | 2.38621116 |
49 | Cortical dysplasia (HP:0002539) | 2.35022369 |
50 | Pendular nystagmus (HP:0012043) | 2.33954943 |
51 | * Hyperpituitarism (HP:0010514) | 2.32749378 |
52 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.31953803 |
53 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.31953803 |
54 | Partial duplication of the phalanx of hand (HP:0009999) | 2.31350154 |
55 | Hypotension (HP:0002615) | 2.30097938 |
56 | Midline defect of the nose (HP:0004122) | 2.30042605 |
57 | Hyperventilation (HP:0002883) | 2.29713802 |
58 | * Aplasia/Hypoplasia of the abdominal wall musculature (HP:0010318) | 2.28297121 |
59 | Genital tract atresia (HP:0001827) | 2.28169937 |
60 | Turricephaly (HP:0000262) | 2.25818232 |
61 | Vaginal atresia (HP:0000148) | 2.25414381 |
62 | Excessive salivation (HP:0003781) | 2.24609781 |
63 | Intestinal atresia (HP:0011100) | 2.24024814 |
64 | Subacute progressive viral hepatitis (HP:0006572) | 2.22995185 |
65 | Bicornuate uterus (HP:0000813) | 2.22368457 |
66 | Adactyly (HP:0009776) | 2.21726880 |
67 | Hemangiomatosis (HP:0007461) | 2.20738826 |
68 | Abnormality of the labia minora (HP:0012880) | 2.20472773 |
69 | Long toe (HP:0010511) | 2.19047485 |
70 | Polycythemia (HP:0001901) | 2.18357657 |
71 | Abnormality of the ischium (HP:0003174) | 2.18026019 |
72 | Abnormality of the musculature of the pelvis (HP:0001469) | 2.16650949 |
73 | Abnormality of the hip-girdle musculature (HP:0001445) | 2.16650949 |
74 | Nephronophthisis (HP:0000090) | 2.15511379 |
75 | Abnormality of the pubic bones (HP:0003172) | 2.14507549 |
76 | Congenital primary aphakia (HP:0007707) | 2.14027967 |
77 | Medial flaring of the eyebrow (HP:0010747) | 2.14008104 |
78 | Decreased circulating renin level (HP:0003351) | 2.08366253 |
79 | Abnormality of the renal medulla (HP:0100957) | 2.07095008 |
80 | Abnormality of the astrocytes (HP:0100707) | 2.06818891 |
81 | Astrocytoma (HP:0009592) | 2.06818891 |
82 | Failure to thrive in infancy (HP:0001531) | 2.06189197 |
83 | Stage 5 chronic kidney disease (HP:0003774) | 2.05773027 |
84 | Gait imbalance (HP:0002141) | 2.03626242 |
85 | Atrophic scars (HP:0001075) | 2.02021369 |
86 | Progressive cerebellar ataxia (HP:0002073) | 2.01147436 |
87 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 2.00866008 |
88 | Interstitial pulmonary disease (HP:0006530) | 11.0466802 |
89 | Overriding aorta (HP:0002623) | 1.99512229 |
90 | Abnormality of sodium homeostasis (HP:0010931) | 1.99476953 |
91 | Hypoparathyroidism (HP:0000829) | 1.99120161 |
92 | Abnormal hair laboratory examination (HP:0003328) | 1.98617392 |
93 | Adrenal overactivity (HP:0002717) | 1.98156694 |
94 | Morphological abnormality of the middle ear (HP:0008609) | 1.98084207 |
95 | Limb-girdle muscle atrophy (HP:0003797) | 1.97597300 |
96 | Stenosis of the external auditory canal (HP:0000402) | 1.97592022 |
97 | Decreased lacrimation (HP:0000633) | 1.95863769 |
98 | Hyperphosphatemia (HP:0002905) | 1.95285297 |
99 | Short tibia (HP:0005736) | 1.92367617 |
100 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.92194888 |
101 | Dyskinesia (HP:0100660) | 1.91568579 |
102 | Shoulder girdle muscle weakness (HP:0003547) | 1.88012636 |
103 | Nasolacrimal duct obstruction (HP:0000579) | 1.87742203 |
104 | Asymmetry of the thorax (HP:0001555) | 1.87367843 |
105 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.87267459 |
106 | Abnormal umbilical cord blood vessels (HP:0011403) | 1.86474703 |
107 | Single umbilical artery (HP:0001195) | 1.86474703 |
108 | Abnormality of the fetal cardiovascular system (HP:0010948) | 1.86474703 |
109 | Bowing of the arm (HP:0006488) | 1.86417836 |
110 | Bowed forearm bones (HP:0003956) | 1.86417836 |
111 | Nephrogenic diabetes insipidus (HP:0009806) | 1.86184071 |
112 | Milia (HP:0001056) | 1.86073640 |
113 | Laryngomalacia (HP:0001601) | 1.85983794 |
114 | Rapidly progressive (HP:0003678) | 1.84897500 |
115 | Hypoventilation (HP:0002791) | 1.84033940 |
116 | Abnormality of the parathyroid morphology (HP:0011766) | 1.82865939 |
117 | Exotropia (HP:0000577) | 1.82606125 |
118 | Bifid scrotum (HP:0000048) | 1.81523280 |
119 | Absent speech (HP:0001344) | 1.80709897 |
120 | Congenital glaucoma (HP:0001087) | 1.80574303 |
121 | Molar tooth sign on MRI (HP:0002419) | 1.80556381 |
122 | Abnormality of midbrain morphology (HP:0002418) | 1.80556381 |
123 | Germ cell neoplasia (HP:0100728) | 1.78842056 |
124 | Abnormal ciliary motility (HP:0012262) | 1.77792733 |
125 | Shawl scrotum (HP:0000049) | 1.77705151 |
126 | Bronchitis (HP:0012387) | 1.75973848 |
127 | Intellectual disability, moderate (HP:0002342) | 1.75245284 |
128 | Labial hypoplasia (HP:0000066) | 1.75010857 |
129 | True hermaphroditism (HP:0010459) | 1.74954140 |
130 | Abnormality of the lacrimal duct (HP:0011481) | 1.73382161 |
131 | Coronal craniosynostosis (HP:0004440) | 1.73076109 |
132 | Abnormality of the nasal mucosa (HP:0000433) | 1.72765676 |
133 | Hypoplasia of dental enamel (HP:0006297) | 1.71967476 |
134 | Specific learning disability (HP:0001328) | 1.70618977 |
135 | Seborrheic dermatitis (HP:0001051) | 1.69792104 |
136 | Alacrima (HP:0000522) | 1.69763381 |
137 | Ulnar claw (HP:0001178) | 1.68767300 |
138 | Progressive sensorineural hearing impairment (HP:0000408) | 1.68403681 |
139 | Neuroblastoma (HP:0003006) | 1.67687891 |
140 | Primitive neuroectodermal tumor (HP:0030065) | 1.67687891 |
141 | Neuroblastic tumors (HP:0004376) | 1.67687891 |
142 | Peripheral primitive neuroectodermal neoplasm (HP:0030067) | 1.67687891 |
143 | Polyphagia (HP:0002591) | 1.66433378 |
144 | Shallow orbits (HP:0000586) | 1.65955720 |
145 | Abnormality of the antihelix (HP:0009738) | 1.65863421 |
146 | Renal hypoplasia (HP:0000089) | 1.65653679 |
147 | Absent hand (HP:0004050) | 1.65349142 |
148 | Alveolar cell carcinoma (HP:0006519) | 1.64449791 |
149 | Patellar aplasia (HP:0006443) | 1.63774027 |
150 | Arnold-Chiari malformation (HP:0002308) | 1.63195238 |
151 | Pulmonary artery stenosis (HP:0004415) | 1.63137560 |
152 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.62593358 |
153 | * Hypothyroidism (HP:0000821) | 1.62075937 |
154 | Abnormality of the pulmonary veins (HP:0011718) | 1.61992929 |
155 | Hypoplastic ischia (HP:0003175) | 1.61809662 |
156 | Postaxial hand polydactyly (HP:0001162) | 1.61802176 |
157 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.61750786 |
158 | Glomerulosclerosis (HP:0000096) | 1.60233612 |
159 | Glioma (HP:0009733) | 1.60200881 |
160 | Chronic otitis media (HP:0000389) | 1.60108728 |
161 | Abnormality of the intervertebral disk (HP:0005108) | 1.59812591 |
162 | Abnormality of the nasolacrimal system (HP:0000614) | 1.59760236 |
163 | Cupped ear (HP:0000378) | 1.58637692 |
164 | Hypoplastic nipples (HP:0002557) | 1.58197205 |
165 | * Thyroid-stimulating hormone excess (HP:0002925) | 1.57989647 |
166 | Tracheomalacia (HP:0002779) | 1.57350860 |
167 | Loss of speech (HP:0002371) | 1.56458516 |
168 | Neoplasm of the tracheobronchial system (HP:0100552) | 1.56378112 |
169 | Chronic hepatic failure (HP:0100626) | 1.56358698 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FGFR2 | 5.22754895 |
2 | CASK | 3.52622080 |
3 | STK24 | 3.25960009 |
4 | EPHA3 | 3.00553123 |
5 | MAP4K2 | 2.86270489 |
6 | DAPK2 | 2.75440646 |
7 | EPHB2 | 2.75084250 |
8 | FER | 2.53389806 |
9 | MET | 2.44726685 |
10 | TIE1 | 2.42941597 |
11 | TRIM28 | 2.42925253 |
12 | MAP3K4 | 2.28301372 |
13 | MAP2K7 | 2.25075603 |
14 | LATS1 | 2.21459604 |
15 | TGFBR2 | 2.18814859 |
16 | ERBB3 | 2.13964744 |
17 | SRPK1 | 2.12800894 |
18 | STK38L | 2.09788583 |
19 | CAMK1G | 1.90159164 |
20 | MAP3K9 | 1.83110010 |
21 | EPHB1 | 1.76804600 |
22 | LRRK2 | 1.76687598 |
23 | EPHA2 | 1.65873012 |
24 | ILK | 1.63465596 |
25 | MST4 | 1.61405569 |
26 | PAK4 | 1.59517021 |
27 | MAPK15 | 1.57885061 |
28 | IRAK2 | 1.49197209 |
29 | CAMK1D | 1.48515842 |
30 | CSNK1A1L | 1.48064452 |
31 | ZAP70 | 1.46247927 |
32 | CSNK1G3 | 1.45641753 |
33 | FRK | 1.43612945 |
34 | MKNK1 | 1.36709098 |
35 | ERBB2 | 1.36325574 |
36 | RIPK1 | 1.31887261 |
37 | MAP3K12 | 1.28977456 |
38 | BCR | 1.28476981 |
39 | MAP3K6 | 1.27349880 |
40 | PDGFRB | 1.26366140 |
41 | LMTK2 | 1.25254159 |
42 | CSNK1G2 | 1.23538696 |
43 | BMPR1B | 1.23017307 |
44 | FES | 1.18087991 |
45 | INSRR | 1.18081819 |
46 | TYRO3 | 1.16056837 |
47 | CSNK1G1 | 1.10389200 |
48 | LIMK1 | 1.10346858 |
49 | MAP3K2 | 1.09404607 |
50 | STK39 | 1.06471649 |
51 | MAP2K2 | 1.04046417 |
52 | FGFR4 | 1.02628073 |
53 | GRK1 | 1.00230015 |
54 | ROCK2 | 0.96786263 |
55 | PTK2 | 0.95442331 |
56 | AKT3 | 0.94949409 |
57 | RPS6KA2 | 0.93404470 |
58 | MKNK2 | 0.91699788 |
59 | SIK2 | 0.90502335 |
60 | PRKD2 | 0.89256667 |
61 | GSK3A | 0.88080111 |
62 | NEK9 | 0.87896192 |
63 | PTK6 | 0.85103144 |
64 | RPS6KA4 | 0.84986863 |
65 | PKN1 | 0.82071377 |
66 | NEK2 | 0.81781161 |
67 | MARK2 | 0.81005729 |
68 | FGFR1 | 0.79416757 |
69 | IRAK1 | 0.78086907 |
70 | KSR2 | 0.77263903 |
71 | MYLK | 0.77074264 |
72 | DAPK3 | 0.75384751 |
73 | TAOK3 | 0.74770758 |
74 | MARK1 | 0.74497477 |
75 | STK10 | 0.72372521 |
76 | NTRK1 | 0.71023142 |
77 | PRKD1 | 0.70935059 |
78 | EPHA4 | 0.70469319 |
79 | OXSR1 | 0.70354353 |
80 | PNCK | 0.70064904 |
81 | YES1 | 0.67999234 |
82 | PHKG1 | 0.67452478 |
83 | PHKG2 | 0.67452478 |
84 | WNK3 | 0.67399932 |
85 | PDGFRA | 0.67269463 |
86 | PRKCE | 0.66622901 |
87 | NTRK3 | 0.65290558 |
88 | UHMK1 | 0.64170519 |
89 | CAMK4 | 0.63433860 |
90 | CAMKK1 | 0.62316432 |
91 | DDR2 | 0.62203545 |
92 | SGK2 | 0.61430552 |
93 | CAMK1 | 0.61033386 |
94 | CDK6 | 0.60420669 |
95 | TESK1 | 0.58528175 |
96 | PRKCZ | 0.57903643 |
97 | BRSK2 | 0.57881669 |
98 | ICK | 0.57620693 |
99 | NTRK2 | 0.55784195 |
100 | SIK3 | 0.55769979 |
101 | MST1R | 0.54277265 |
102 | PAK3 | 0.54033604 |
103 | BLK | 0.53651792 |
104 | SIK1 | 0.53431954 |
105 | ERBB4 | 0.53276497 |
106 | CSNK1A1 | 0.52870105 |
107 | DYRK2 | 0.52178502 |
108 | MAP3K7 | 0.51591554 |
109 | TRIB3 | 0.50104398 |
110 | KSR1 | 0.49766017 |
111 | PLK2 | 0.48803364 |
112 | ROCK1 | 0.48677881 |
113 | CHUK | 0.48309135 |
114 | FGR | 0.48040921 |
115 | DYRK1B | 0.47047224 |
116 | CSNK1D | 0.44841782 |
117 | PRKCQ | 0.44215361 |
118 | MAP2K4 | 0.43852050 |
119 | MAPK10 | 0.42240507 |
120 | PRKAA1 | 0.42239044 |
121 | SGK223 | 0.42057366 |
122 | SGK494 | 0.42057366 |
123 | DYRK3 | 0.41683330 |
124 | DAPK1 | 0.40740989 |
125 | RET | 0.40230774 |
126 | BRD4 | 0.39617080 |
127 | EGFR | 0.39054857 |
128 | RPS6KA5 | 0.38920169 |
129 | FYN | 0.38862204 |
130 | MAPK13 | 0.38678654 |
131 | CDK19 | 0.38661038 |
132 | PRPF4B | 0.38191775 |
133 | CDC42BPA | 0.38025280 |
134 | CAMK2B | 0.37973858 |
135 | ABL1 | 0.37426175 |
136 | RPS6KL1 | 0.37313308 |
137 | RPS6KC1 | 0.37313308 |
138 | CDK5 | 0.35793952 |
139 | CCNB1 | 0.35550005 |
140 | MAPK9 | 0.34435990 |
141 | CAMK2A | 0.33681822 |
142 | SGK3 | 0.32694280 |
143 | TAOK1 | 0.30113667 |
144 | ATM | 0.30004095 |
145 | MAPK7 | 0.29316484 |
146 | PRKACB | 0.28895083 |
147 | AKT2 | 0.28121414 |
148 | IGF1R | 0.27821868 |
149 | STK38 | 0.27453981 |
150 | ATR | 0.27428551 |
151 | MAPK8 | 0.27162812 |
152 | NLK | 0.25553383 |
153 | PRKACA | 0.24663255 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.24346685 |
2 | Mineral absorption_Homo sapiens_hsa04978 | 2.75370337 |
3 | Notch signaling pathway_Homo sapiens_hsa04330 | 2.70392790 |
4 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.68858405 |
5 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 2.63745935 |
6 | Protein export_Homo sapiens_hsa03060 | 2.49614670 |
7 | Circadian rhythm_Homo sapiens_hsa04710 | 2.42936463 |
8 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 2.42585339 |
9 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 2.25369744 |
10 | ABC transporters_Homo sapiens_hsa02010 | 2.20174789 |
11 | Axon guidance_Homo sapiens_hsa04360 | 2.15189496 |
12 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 2.12324191 |
13 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.02268131 |
14 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.92101597 |
15 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.84994415 |
16 | Histidine metabolism_Homo sapiens_hsa00340 | 1.81984744 |
17 | Taste transduction_Homo sapiens_hsa04742 | 1.81604155 |
18 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.74899216 |
19 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.69392818 |
20 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.67587318 |
21 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.58367894 |
22 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.56004102 |
23 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.55153671 |
24 | Salivary secretion_Homo sapiens_hsa04970 | 1.54389009 |
25 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.53221253 |
26 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.50403576 |
27 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.49707565 |
28 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.48104642 |
29 | Tight junction_Homo sapiens_hsa04530 | 1.47056605 |
30 | Bladder cancer_Homo sapiens_hsa05219 | 1.45727298 |
31 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.44631870 |
32 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.44470065 |
33 | Nicotine addiction_Homo sapiens_hsa05033 | 1.43632699 |
34 | Adherens junction_Homo sapiens_hsa04520 | 1.43454991 |
35 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.36896106 |
36 | Renin secretion_Homo sapiens_hsa04924 | 1.33797947 |
37 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.26663280 |
38 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.25818145 |
39 | Phagosome_Homo sapiens_hsa04145 | 1.25195363 |
40 | Lysosome_Homo sapiens_hsa04142 | 1.22770921 |
41 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.22404374 |
42 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.21934104 |
43 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.19107836 |
44 | Melanogenesis_Homo sapiens_hsa04916 | 1.18501274 |
45 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.18044721 |
46 | Cocaine addiction_Homo sapiens_hsa05030 | 1.17925547 |
47 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.17808993 |
48 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.16282777 |
49 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.16060355 |
50 | Basal transcription factors_Homo sapiens_hsa03022 | 1.14644275 |
51 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.14036511 |
52 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.11726762 |
53 | Endometrial cancer_Homo sapiens_hsa05213 | 1.08074428 |
54 | Spliceosome_Homo sapiens_hsa03040 | 1.07389560 |
55 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.07157778 |
56 | Morphine addiction_Homo sapiens_hsa05032 | 1.03586969 |
57 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 1.02496208 |
58 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.02096815 |
59 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.01579257 |
60 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.01577912 |
61 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.00691222 |
62 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.98858385 |
63 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.97491458 |
64 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.97037104 |
65 | Circadian entrainment_Homo sapiens_hsa04713 | 0.96541477 |
66 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.96005288 |
67 | Gap junction_Homo sapiens_hsa04540 | 0.95101773 |
68 | Focal adhesion_Homo sapiens_hsa04510 | 0.94888295 |
69 | Long-term depression_Homo sapiens_hsa04730 | 0.93292777 |
70 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.92736321 |
71 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.92121583 |
72 | GABAergic synapse_Homo sapiens_hsa04727 | 0.91709702 |
73 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.90737591 |
74 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.89584474 |
75 | Amoebiasis_Homo sapiens_hsa05146 | 0.89544635 |
76 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.89374588 |
77 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.86973216 |
78 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.86736118 |
79 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.86092647 |
80 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.85928191 |
81 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.84854571 |
82 | Pathways in cancer_Homo sapiens_hsa05200 | 0.84635819 |
83 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.84476828 |
84 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.80699363 |
85 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.80279919 |
86 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.78593797 |
87 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.78214668 |
88 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.77440081 |
89 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.76293191 |
90 | Melanoma_Homo sapiens_hsa05218 | 0.76055537 |
91 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.75685060 |
92 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.75633891 |
93 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.75071847 |
94 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.74854084 |
95 | Colorectal cancer_Homo sapiens_hsa05210 | 0.74452738 |
96 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.73430962 |
97 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.73326437 |
98 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.72243077 |
99 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.72006906 |
100 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.71527687 |
101 | Pertussis_Homo sapiens_hsa05133 | 0.71498139 |
102 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.70434908 |
103 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.69772506 |
104 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.69258164 |
105 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.67970795 |
106 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.67793997 |
107 | Phototransduction_Homo sapiens_hsa04744 | 0.67597113 |
108 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.67549129 |
109 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.66606724 |
110 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.65676849 |
111 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.64753805 |
112 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.63899417 |
113 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.63515944 |
114 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.63283441 |
115 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.63226460 |
116 | Lysine degradation_Homo sapiens_hsa00310 | 0.62156589 |
117 | Endocytosis_Homo sapiens_hsa04144 | 0.61673720 |
118 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.61651568 |
119 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.61005088 |
120 | Thyroid cancer_Homo sapiens_hsa05216 | 0.60776210 |
121 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.60165035 |
122 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.60116478 |
123 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.60081635 |
124 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.59090075 |
125 | Long-term potentiation_Homo sapiens_hsa04720 | 0.58937160 |
126 | Peroxisome_Homo sapiens_hsa04146 | 0.57506559 |
127 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.57437628 |
128 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.56815107 |
129 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.56633809 |
130 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.56205071 |
131 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.55957294 |
132 | Insulin secretion_Homo sapiens_hsa04911 | 0.54447067 |
133 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.53499638 |
134 | Malaria_Homo sapiens_hsa05144 | 0.51838357 |
135 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.51320529 |
136 | Prion diseases_Homo sapiens_hsa05020 | 0.51036573 |
137 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.50741251 |
138 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.50248700 |
139 | Platelet activation_Homo sapiens_hsa04611 | 0.49664435 |
140 | Glioma_Homo sapiens_hsa05214 | 0.48628350 |
141 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.46857264 |
142 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.46400130 |
143 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.45376469 |
144 | Retinol metabolism_Homo sapiens_hsa00830 | 0.42466463 |
145 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.38974282 |
146 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.36957171 |
147 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.35411400 |
148 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.34275597 |
149 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.30654712 |
150 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.28627746 |