

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | * nucleoside diphosphate phosphorylation (GO:0006165) | 8.52210417 |
| 2 | ventricular system development (GO:0021591) | 8.46976835 |
| 3 | * GTP biosynthetic process (GO:0006183) | 8.35907328 |
| 4 | left/right axis specification (GO:0070986) | 8.35820842 |
| 5 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 8.02331337 |
| 6 | motile cilium assembly (GO:0044458) | 7.97677270 |
| 7 | * UTP biosynthetic process (GO:0006228) | 7.27977379 |
| 8 | microtubule bundle formation (GO:0001578) | 7.09521924 |
| 9 | * UTP metabolic process (GO:0046051) | 6.70937829 |
| 10 | left/right pattern formation (GO:0060972) | 6.00612127 |
| 11 | intraciliary transport (GO:0042073) | 5.74519735 |
| 12 | cilium organization (GO:0044782) | 5.71944361 |
| 13 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 5.37060083 |
| 14 | * CTP metabolic process (GO:0046036) | 5.29051955 |
| 15 | * CTP biosynthetic process (GO:0006241) | 5.29051955 |
| 16 | regulation of macrophage chemotaxis (GO:0010758) | 5.25406426 |
| 17 | cilium assembly (GO:0042384) | 5.21691546 |
| 18 | * guanosine-containing compound biosynthetic process (GO:1901070) | 5.17422812 |
| 19 | positive regulation of action potential (GO:0045760) | 4.95707241 |
| 20 | * nucleotide phosphorylation (GO:0046939) | 4.81455951 |
| 21 | regulation of mononuclear cell migration (GO:0071675) | 4.77804107 |
| 22 | one-carbon compound transport (GO:0019755) | 4.73954701 |
| 23 | * pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 4.73877374 |
| 24 | brain morphogenesis (GO:0048854) | 4.71773804 |
| 25 | cellular component assembly involved in morphogenesis (GO:0010927) | 4.69806864 |
| 26 | protein localization to cilium (GO:0061512) | 4.53515643 |
| 27 | * pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) | 4.48988372 |
| 28 | microtubule-based movement (GO:0007018) | 4.48532702 |
| 29 | multicellular organismal aging (GO:0010259) | 4.30054665 |
| 30 | response to pheromone (GO:0019236) | 4.27994187 |
| 31 | cilium morphogenesis (GO:0060271) | 4.18506569 |
| 32 | cell projection assembly (GO:0030031) | 4.16931951 |
| 33 | centriole assembly (GO:0098534) | 4.15917596 |
| 34 | tachykinin receptor signaling pathway (GO:0007217) | 4.06509559 |
| 35 | nonmotile primary cilium assembly (GO:0035058) | 4.05160230 |
| 36 | * nucleoside diphosphate metabolic process (GO:0009132) | 3.96356852 |
| 37 | photoreceptor cell maintenance (GO:0045494) | 3.82036973 |
| 38 | central nervous system myelination (GO:0022010) | 3.78346591 |
| 39 | axon ensheathment in central nervous system (GO:0032291) | 3.78346591 |
| 40 | regulation of action potential (GO:0098900) | 3.78283011 |
| 41 | positive regulation of cellular response to insulin stimulus (GO:1900078) | 3.77415173 |
| 42 | otic vesicle formation (GO:0030916) | 3.77041395 |
| 43 | * pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 3.76318137 |
| 44 | regulation of cilium movement (GO:0003352) | 3.75661084 |
| 45 | eye photoreceptor cell differentiation (GO:0001754) | 3.71109930 |
| 46 | photoreceptor cell differentiation (GO:0046530) | 3.71109930 |
| 47 | retinal rod cell development (GO:0046548) | 3.63685478 |
| 48 | primary alcohol catabolic process (GO:0034310) | 3.52788787 |
| 49 | microtubule depolymerization (GO:0007019) | 3.51295996 |
| 50 | negative regulation of heart rate (GO:0010459) | 3.46189544 |
| 51 | vitamin transmembrane transport (GO:0035461) | 3.40836010 |
| 52 | base-excision repair, AP site formation (GO:0006285) | 3.36358788 |
| 53 | histone H2A acetylation (GO:0043968) | 3.36230976 |
| 54 | gas transport (GO:0015669) | 3.32997829 |
| 55 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.31459031 |
| 56 | regulation of pigment cell differentiation (GO:0050932) | 3.29893658 |
| 57 | microtubule severing (GO:0051013) | 3.28108745 |
| 58 | limb bud formation (GO:0060174) | 3.26624799 |
| 59 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 3.25598140 |
| 60 | negative regulation of B cell mediated immunity (GO:0002713) | 3.25598140 |
| 61 | * pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 3.24715593 |
| 62 | smoothened signaling pathway (GO:0007224) | 3.23454789 |
| 63 | sperm motility (GO:0030317) | 3.22108531 |
| 64 | lateral ventricle development (GO:0021670) | 3.21360347 |
| 65 | diterpenoid biosynthetic process (GO:0016102) | 3.21058743 |
| 66 | neural tube formation (GO:0001841) | 3.20003211 |
| 67 | ethanol metabolic process (GO:0006067) | 3.07726750 |
| 68 | determination of left/right symmetry (GO:0007368) | 3.07639860 |
| 69 | protein K11-linked deubiquitination (GO:0035871) | 3.06884910 |
| 70 | positive regulation of digestive system process (GO:0060456) | 3.04685774 |
| 71 | determination of bilateral symmetry (GO:0009855) | 2.98722754 |
| 72 | negative regulation of inclusion body assembly (GO:0090084) | 2.95900211 |
| 73 | specification of symmetry (GO:0009799) | 2.94482868 |
| 74 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.94378126 |
| 75 | deoxyribonucleoside diphosphate metabolic process (GO:0009186) | 2.91910676 |
| 76 | retinal cone cell development (GO:0046549) | 2.91760418 |
| 77 | endocardial cushion morphogenesis (GO:0003203) | 2.90828208 |
| 78 | embryonic digestive tract development (GO:0048566) | 2.90480987 |
| 79 | ADP metabolic process (GO:0046031) | 2.88006184 |
| 80 | establishment of apical/basal cell polarity (GO:0035089) | 2.86367449 |
| 81 | aldehyde catabolic process (GO:0046185) | 2.83344141 |
| 82 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.82576439 |
| 83 | negative regulation of humoral immune response (GO:0002921) | 2.81637521 |
| 84 | microtubule polymerization or depolymerization (GO:0031109) | 2.81393077 |
| 85 | retinoic acid metabolic process (GO:0042573) | 2.78536964 |
| 86 | terpenoid biosynthetic process (GO:0016114) | 2.77722188 |
| 87 | positive regulation of meiosis (GO:0045836) | 2.74024587 |
| 88 | oxygen transport (GO:0015671) | 2.73261151 |
| 89 | hair follicle development (GO:0001942) | 2.73152240 |
| 90 | surfactant homeostasis (GO:0043129) | 2.72263800 |
| 91 | * purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.71774972 |
| 92 | negative regulation of T cell differentiation in thymus (GO:0033085) | 2.70790208 |
| 93 | regulation of mesenchymal cell apoptotic process (GO:2001053) | 2.70762628 |
| 94 | negative regulation of cAMP-mediated signaling (GO:0043951) | 2.66846862 |
| 95 | centriole replication (GO:0007099) | 2.66590452 |
| 96 | organelle assembly (GO:0070925) | 2.65676647 |
| 97 | heart valve formation (GO:0003188) | 2.64763369 |
| 98 | * purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.63819422 |
| 99 | cerebral cortex neuron differentiation (GO:0021895) | 2.63135785 |
| 100 | response to nitrosative stress (GO:0051409) | 2.62806416 |
| 101 | * pyrimidine ribonucleoside biosynthetic process (GO:0046132) | 2.62216220 |
| 102 | cytoplasmic microtubule organization (GO:0031122) | 2.61792685 |
| 103 | lung epithelium development (GO:0060428) | 2.59725157 |
| 104 | positive regulation of meiotic cell cycle (GO:0051446) | 2.57618103 |
| 105 | response to xenobiotic stimulus (GO:0009410) | 2.57056459 |
| 106 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 2.56378902 |
| 107 | regulation of hippo signaling (GO:0035330) | 2.55842950 |
| 108 | ubiquinone biosynthetic process (GO:0006744) | 2.55552945 |
| 109 | protein polyglutamylation (GO:0018095) | 2.53532702 |
| 110 | ubiquinone metabolic process (GO:0006743) | 2.51543249 |
| 111 | presynaptic membrane assembly (GO:0097105) | 2.51498575 |
| 112 | establishment of monopolar cell polarity (GO:0061162) | 2.50052297 |
| 113 | establishment or maintenance of monopolar cell polarity (GO:0061339) | 2.50052297 |
| 114 | * pyrimidine ribonucleotide biosynthetic process (GO:0009220) | 2.49715828 |
| 115 | regulation of collateral sprouting (GO:0048670) | 2.48619130 |
| 116 | regulation of germinal center formation (GO:0002634) | 2.47269532 |
| 117 | regulation of vacuole organization (GO:0044088) | 2.46629439 |
| 118 | DNA integration (GO:0015074) | 2.45974525 |
| 119 | auditory behavior (GO:0031223) | 2.45967727 |
| 120 | glomerular epithelial cell development (GO:0072310) | 2.45936057 |
| 121 | prenylation (GO:0097354) | 2.45467961 |
| 122 | protein prenylation (GO:0018342) | 2.45467961 |
| 123 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.44963593 |
| 124 | detection of light stimulus involved in visual perception (GO:0050908) | 2.44963593 |
| 125 | exogenous drug catabolic process (GO:0042738) | 2.44783011 |
| 126 | positive regulation of developmental pigmentation (GO:0048087) | 2.44308994 |
| 127 | behavioral response to nicotine (GO:0035095) | 2.43151785 |
| 128 | protein complex biogenesis (GO:0070271) | 2.42813525 |
| 129 | L-fucose catabolic process (GO:0042355) | 2.42029796 |
| 130 | fucose catabolic process (GO:0019317) | 2.42029796 |
| 131 | L-fucose metabolic process (GO:0042354) | 2.42029796 |
| 132 | developmental induction (GO:0031128) | 2.41898888 |
| 133 | regulation of microtubule-based movement (GO:0060632) | 2.41439744 |
| 134 | * nucleoside triphosphate biosynthetic process (GO:0009142) | 2.40958418 |
| 135 | nephron tubule formation (GO:0072079) | 2.40832597 |
| 136 | transmission of nerve impulse (GO:0019226) | 2.40794862 |
| 137 | polyketide metabolic process (GO:0030638) | 2.40303229 |
| 138 | doxorubicin metabolic process (GO:0044598) | 2.40303229 |
| 139 | daunorubicin metabolic process (GO:0044597) | 2.40303229 |
| 140 | nucleobase catabolic process (GO:0046113) | 2.39274162 |
| 141 | neurotransmitter catabolic process (GO:0042135) | 2.39141250 |
| 142 | cornea development in camera-type eye (GO:0061303) | 2.39102192 |
| 143 | regulation of glucocorticoid secretion (GO:2000849) | 2.39064348 |
| 144 | cell-cell signaling involved in cell fate commitment (GO:0045168) | 2.38495283 |
| 145 | photoreceptor cell development (GO:0042461) | 2.38402022 |
| 146 | vocalization behavior (GO:0071625) | 2.38380538 |
| 147 | positive regulation of vesicle fusion (GO:0031340) | 2.37915342 |
| 148 | protein refolding (GO:0042026) | 2.37690709 |
| 149 | positive regulation of steroid hormone secretion (GO:2000833) | 2.34998405 |
| 150 | epithelial tube branching involved in lung morphogenesis (GO:0060441) | 2.34302765 |
| 151 | positive regulation of smoothened signaling pathway (GO:0045880) | 2.33782247 |
| 152 | pyrimidine-containing compound transmembrane transport (GO:0072531) | 2.33695723 |
| 153 | ethanol oxidation (GO:0006069) | 2.33628133 |
| 154 | platelet dense granule organization (GO:0060155) | 2.32755825 |
| 155 | neurotransmitter metabolic process (GO:0042133) | 2.30290614 |
| 156 | epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198) | 2.28450345 |
| 157 | microtubule-based process (GO:0007017) | 2.27822723 |
| 158 | regulation of granulocyte chemotaxis (GO:0071622) | 2.27440223 |
| 159 | * ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.25902368 |
| 160 | negative regulation of oligodendrocyte differentiation (GO:0048715) | 2.25282220 |
| 161 | meiotic cell cycle (GO:0051321) | 2.24842219 |
| 162 | cilium movement (GO:0003341) | 17.1651382 |
| 163 | axoneme assembly (GO:0035082) | 16.7565685 |
| 164 | axonemal dynein complex assembly (GO:0070286) | 14.0589280 |
| 165 | cilium or flagellum-dependent cell motility (GO:0001539) | 12.8586866 |
| 166 | epithelial cilium movement (GO:0003351) | 11.5348187 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 3.16904033 |
| 2 | IGF1R_20145208_ChIP-Seq_DFB_Human | 3.15554411 |
| 3 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 3.13323513 |
| 4 | VDR_22108803_ChIP-Seq_LS180_Human | 3.07494645 |
| 5 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.92852072 |
| 6 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.91857093 |
| 7 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.76180359 |
| 8 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.71367122 |
| 9 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.44278305 |
| 10 | FUS_26573619_Chip-Seq_HEK293_Human | 2.36428111 |
| 11 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.32319005 |
| 12 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.15690542 |
| 13 | GATA1_22025678_ChIP-Seq_K562_Human | 2.11891555 |
| 14 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.08859262 |
| 15 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.99080469 |
| 16 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.98907701 |
| 17 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.92713288 |
| 18 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.84177892 |
| 19 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.84017405 |
| 20 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.83548905 |
| 21 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.81505777 |
| 22 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 1.77935473 |
| 23 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.77132576 |
| 24 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.76373836 |
| 25 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.74844367 |
| 26 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.69199433 |
| 27 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.67238080 |
| 28 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.66918425 |
| 29 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.66595865 |
| 30 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.62657909 |
| 31 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.62009992 |
| 32 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.60977529 |
| 33 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.60118744 |
| 34 | P300_19829295_ChIP-Seq_ESCs_Human | 1.59828853 |
| 35 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.57612337 |
| 36 | TCF4_23295773_ChIP-Seq_U87_Human | 1.57282119 |
| 37 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.56372112 |
| 38 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.55927106 |
| 39 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.54503287 |
| 40 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.54503287 |
| 41 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.53813044 |
| 42 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.53009765 |
| 43 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.48821093 |
| 44 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.48541427 |
| 45 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.47827269 |
| 46 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.47758312 |
| 47 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.47400717 |
| 48 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.47241982 |
| 49 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.45752619 |
| 50 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.44264330 |
| 51 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.43885065 |
| 52 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.43751464 |
| 53 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.42980248 |
| 54 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.42390136 |
| 55 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.41540821 |
| 56 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.40655532 |
| 57 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.39043252 |
| 58 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.39043252 |
| 59 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.38303249 |
| 60 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.38145617 |
| 61 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.38020641 |
| 62 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.37193699 |
| 63 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.36563184 |
| 64 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.36490341 |
| 65 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.35584077 |
| 66 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.35277619 |
| 67 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.33619257 |
| 68 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.30263825 |
| 69 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.29340046 |
| 70 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.28953671 |
| 71 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.28811493 |
| 72 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.25863810 |
| 73 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.25256127 |
| 74 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.24826574 |
| 75 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.24311076 |
| 76 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.24311076 |
| 77 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.24064420 |
| 78 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.23835088 |
| 79 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.21789677 |
| 80 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.21631817 |
| 81 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.21474381 |
| 82 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.21474381 |
| 83 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.20851254 |
| 84 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.20836398 |
| 85 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.20188957 |
| 86 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.19627120 |
| 87 | CJUN_26792858_Chip-Seq_BT549_Human | 1.19453765 |
| 88 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.19401672 |
| 89 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.18955801 |
| 90 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.18638599 |
| 91 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.18257199 |
| 92 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.17914885 |
| 93 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.17341889 |
| 94 | ETV1_20927104_ChIP-Seq_GIST48_Human | 1.16995610 |
| 95 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.16927873 |
| 96 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.16658757 |
| 97 | AR_20517297_ChIP-Seq_VCAP_Human | 1.16478944 |
| 98 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.15986909 |
| 99 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.15951733 |
| 100 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.14370219 |
| 101 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.14088079 |
| 102 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.13959034 |
| 103 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.12380060 |
| 104 | EWS_26573619_Chip-Seq_HEK293_Human | 1.11951534 |
| 105 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.11411231 |
| 106 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.11054984 |
| 107 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.11027191 |
| 108 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.09563657 |
| 109 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.08856617 |
| 110 | RXR_22108803_ChIP-Seq_LS180_Human | 1.07793228 |
| 111 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.07481068 |
| 112 | PHF8_20622853_ChIP-Seq_HELA_Human | 1.07319005 |
| 113 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.06767617 |
| 114 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.05781350 |
| 115 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 1.05634558 |
| 116 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.04879429 |
| 117 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.04818787 |
| 118 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.04818787 |
| 119 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.04460371 |
| 120 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.04192739 |
| 121 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.03689049 |
| 122 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.03664685 |
| 123 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.03592304 |
| 124 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.03371852 |
| 125 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.02278669 |
| 126 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.02117589 |
| 127 | STAT3_23295773_ChIP-Seq_U87_Human | 1.01939424 |
| 128 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.01311500 |
| 129 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.00974679 |
| 130 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.00647404 |
| 131 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.00572871 |
| 132 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.00051366 |
| 133 | NFYB_21822215_ChIP-Seq_K562_Human | 1.00043066 |
| 134 | TBL1_22424771_ChIP-Seq_293T_Human | 0.98082478 |
| 135 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.97759860 |
| 136 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.97642241 |
| 137 | LMO2_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.96865518 |
| 138 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.96625092 |
| 139 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.96573850 |
| 140 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.96520977 |
| 141 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.96490876 |
| 142 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.96199650 |
| 143 | ZFX_18555785_Chip-Seq_ESCs_Mouse | 0.94850790 |
| 144 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.94260568 |
| 145 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.93911646 |
| 146 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.93856696 |
| 147 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.93585621 |
| 148 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.93400785 |
| 149 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.93225177 |
| 150 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.92854726 |
| 151 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.92811653 |
| 152 | AR_25329375_ChIP-Seq_VCAP_Human | 0.91978999 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003136_yellow_coat_color | 7.19866012 |
| 2 | MP0002653_abnormal_ependyma_morphology | 4.31239422 |
| 3 | MP0005623_abnormal_meninges_morphology | 4.20282536 |
| 4 | MP0004782_abnormal_surfactant_physiolog | 3.35402882 |
| 5 | MP0010386_abnormal_urinary_bladder | 3.25172997 |
| 6 | MP0008004_abnormal_stomach_pH | 2.70244125 |
| 7 | MP0005646_abnormal_pituitary_gland | 2.64487301 |
| 8 | MP0004133_heterotaxia | 2.59503079 |
| 9 | MP0004043_abnormal_pH_regulation | 2.48128046 |
| 10 | MP0008789_abnormal_olfactory_epithelium | 2.47907207 |
| 11 | MP0002282_abnormal_trachea_morphology | 2.39379945 |
| 12 | MP0001958_emphysema | 2.27272063 |
| 13 | MP0003724_increased_susceptibility_to | 2.25173264 |
| 14 | MP0005167_abnormal_blood-brain_barrier | 2.22865145 |
| 15 | MP0003690_abnormal_glial_cell | 2.11918141 |
| 16 | MP0005253_abnormal_eye_physiology | 2.07590090 |
| 17 | MP0003646_muscle_fatigue | 2.07467160 |
| 18 | MP0001440_abnormal_grooming_behavior | 2.04022491 |
| 19 | MP0003787_abnormal_imprinting | 2.03859465 |
| 20 | MP0006072_abnormal_retinal_apoptosis | 2.01431171 |
| 21 | MP0002132_abnormal_respiratory_system | 1.99712089 |
| 22 | MP0003303_peritoneal_inflammation | 1.99635120 |
| 23 | MP0002133_abnormal_respiratory_system | 1.99144000 |
| 24 | MP0005388_respiratory_system_phenotype | 1.99144000 |
| 25 | MP0000383_abnormal_hair_follicle | 1.97541408 |
| 26 | MP0005394_taste/olfaction_phenotype | 1.95883067 |
| 27 | MP0005499_abnormal_olfactory_system | 1.95883067 |
| 28 | MP0004858_abnormal_nervous_system | 1.91749058 |
| 29 | MP0001529_abnormal_vocalization | 1.89769715 |
| 30 | MP0004381_abnormal_hair_follicle | 1.89442103 |
| 31 | MP0001177_atelectasis | 1.88033594 |
| 32 | MP0010678_abnormal_skin_adnexa | 1.78488643 |
| 33 | MP0002249_abnormal_larynx_morphology | 1.73067069 |
| 34 | MP0000569_abnormal_digit_pigmentation | 1.69339950 |
| 35 | MP0003937_abnormal_limbs/digits/tail_de | 1.66035547 |
| 36 | MP0002332_abnormal_exercise_endurance | 1.65309040 |
| 37 | MP0002638_abnormal_pupillary_reflex | 1.63051067 |
| 38 | MP0009046_muscle_twitch | 1.60720173 |
| 39 | MP0001851_eye_inflammation | 1.60715670 |
| 40 | MP0002735_abnormal_chemical_nociception | 1.57714979 |
| 41 | MP0001486_abnormal_startle_reflex | 1.57564029 |
| 42 | MP0001879_abnormal_lymphatic_vessel | 1.56734961 |
| 43 | MP0002168_other_aberrant_phenotype | 1.54742018 |
| 44 | MP0006276_abnormal_autonomic_nervous | 1.54056562 |
| 45 | MP0004272_abnormal_basement_membrane | 1.48201822 |
| 46 | MP0008875_abnormal_xenobiotic_pharmacok | 1.47582641 |
| 47 | MP0006292_abnormal_olfactory_placode | 1.45601048 |
| 48 | MP0008877_abnormal_DNA_methylation | 1.44618242 |
| 49 | MP0000566_synostosis | 1.42137323 |
| 50 | MP0003195_calcinosis | 1.42098906 |
| 51 | MP0001968_abnormal_touch/_nociception | 1.41034769 |
| 52 | MP0004147_increased_porphyrin_level | 1.39408682 |
| 53 | MP0002160_abnormal_reproductive_system | 1.39240420 |
| 54 | MP0002272_abnormal_nervous_system | 1.38612685 |
| 55 | MP0001970_abnormal_pain_threshold | 1.36286036 |
| 56 | MP0004885_abnormal_endolymph | 1.35129880 |
| 57 | MP0008995_early_reproductive_senescence | 1.33054364 |
| 58 | MP0003634_abnormal_glial_cell | 1.32621431 |
| 59 | MP0005248_abnormal_Harderian_gland | 1.31679538 |
| 60 | MP0000778_abnormal_nervous_system | 1.31043920 |
| 61 | MP0001984_abnormal_olfaction | 1.30830412 |
| 62 | MP0009780_abnormal_chondrocyte_physiolo | 1.27661463 |
| 63 | MP0003950_abnormal_plasma_membrane | 1.27092932 |
| 64 | MP0002557_abnormal_social/conspecific_i | 1.25051606 |
| 65 | MP0001270_distended_abdomen | 1.23922677 |
| 66 | MP0003283_abnormal_digestive_organ | 1.23875857 |
| 67 | MP0002928_abnormal_bile_duct | 1.21947833 |
| 68 | MP0002876_abnormal_thyroid_physiology | 1.21027985 |
| 69 | MP0002234_abnormal_pharynx_morphology | 1.18914856 |
| 70 | MP0000428_abnormal_craniofacial_morphol | 1.18061358 |
| 71 | MP0005389_reproductive_system_phenotype | 1.15677754 |
| 72 | MP0008872_abnormal_physiological_respon | 1.15387648 |
| 73 | MP0002163_abnormal_gland_morphology | 1.13988498 |
| 74 | MP0004142_abnormal_muscle_tone | 1.13736159 |
| 75 | MP0005645_abnormal_hypothalamus_physiol | 1.12195130 |
| 76 | MP0003938_abnormal_ear_development | 1.10835146 |
| 77 | MP0000372_irregular_coat_pigmentation | 1.10150757 |
| 78 | MP0003075_altered_response_to | 1.08654126 |
| 79 | MP0002736_abnormal_nociception_after | 1.08240278 |
| 80 | MP0002822_catalepsy | 1.07743082 |
| 81 | MP0003698_abnormal_male_reproductive | 1.07695676 |
| 82 | MP0001324_abnormal_eye_pigmentation | 1.06885083 |
| 83 | MP0001986_abnormal_taste_sensitivity | 1.04884747 |
| 84 | MP0004742_abnormal_vestibular_system | 1.04311824 |
| 85 | MP0009384_cardiac_valve_regurgitation | 1.03882286 |
| 86 | MP0003121_genomic_imprinting | 1.03506447 |
| 87 | MP0002277_abnormal_respiratory_mucosa | 1.02177638 |
| 88 | MP0001501_abnormal_sleep_pattern | 1.01239558 |
| 89 | MP0004145_abnormal_muscle_electrophysio | 0.99923626 |
| 90 | MP0008058_abnormal_DNA_repair | 0.99702531 |
| 91 | MP0002063_abnormal_learning/memory/cond | 0.99477420 |
| 92 | MP0002938_white_spotting | 0.99285882 |
| 93 | MP0005395_other_phenotype | 0.98925300 |
| 94 | MP0002254_reproductive_system_inflammat | 0.98107717 |
| 95 | MP0005423_abnormal_somatic_nervous | 0.96909433 |
| 96 | MP0002909_abnormal_adrenal_gland | 0.96859201 |
| 97 | MP0002233_abnormal_nose_morphology | 0.96180768 |
| 98 | MP0002572_abnormal_emotion/affect_behav | 0.96059177 |
| 99 | MP0002067_abnormal_sensory_capabilities | 0.94635983 |
| 100 | MP0005075_abnormal_melanosome_morpholog | 0.94227895 |
| 101 | MP0002752_abnormal_somatic_nervous | 0.93173071 |
| 102 | MP0001929_abnormal_gametogenesis | 0.93002647 |
| 103 | MP0005195_abnormal_posterior_eye | 0.92662003 |
| 104 | MP0002064_seizures | 0.91268513 |
| 105 | MP0003122_maternal_imprinting | 0.91251247 |
| 106 | MP0005391_vision/eye_phenotype | 0.90927768 |
| 107 | MP0001765_abnormal_ion_homeostasis | 0.90677536 |
| 108 | MP0002405_respiratory_system_inflammati | 0.90553179 |
| 109 | MP0003656_abnormal_erythrocyte_physiolo | 0.89441660 |
| 110 | MP0005595_abnormal_vascular_smooth | 0.88954179 |
| 111 | MP0000462_abnormal_digestive_system | 0.88357604 |
| 112 | MP0005377_hearing/vestibular/ear_phenot | 0.87834442 |
| 113 | MP0003878_abnormal_ear_physiology | 0.87834442 |
| 114 | MP0009250_abnormal_appendicular_skeleto | 0.87622354 |
| 115 | MP0003011_delayed_dark_adaptation | 0.87467376 |
| 116 | MP0000049_abnormal_middle_ear | 0.87421459 |
| 117 | MP0000613_abnormal_salivary_gland | 0.86939088 |
| 118 | MP0009745_abnormal_behavioral_response | 0.86365952 |
| 119 | MP0002229_neurodegeneration | 0.86141599 |
| 120 | MP0002734_abnormal_mechanical_nocicepti | 0.85672600 |
| 121 | MP0005551_abnormal_eye_electrophysiolog | 0.85015217 |
| 122 | MP0004924_abnormal_behavior | 0.84714858 |
| 123 | MP0005386_behavior/neurological_phenoty | 0.84714858 |
| 124 | MP0005084_abnormal_gallbladder_morpholo | 0.84562532 |
| 125 | MP0001293_anophthalmia | 0.84275308 |
| 126 | MP0000955_abnormal_spinal_cord | 0.84192899 |
| 127 | MP0005164_abnormal_response_to | 0.83832559 |
| 128 | MP0002184_abnormal_innervation | 0.82465430 |
| 129 | MP0002882_abnormal_neuron_morphology | 0.81589069 |
| 130 | MP0005083_abnormal_biliary_tract | 0.80235859 |
| 131 | MP0003635_abnormal_synaptic_transmissio | 0.80135703 |
| 132 | MP0005670_abnormal_white_adipose | 0.78663715 |
| 133 | MP0002751_abnormal_autonomic_nervous | 0.77243631 |
| 134 | MP0002095_abnormal_skin_pigmentation | 0.77122531 |
| 135 | MP0001849_ear_inflammation | 0.76280661 |
| 136 | MP0000750_abnormal_muscle_regeneration | 0.75057542 |
| 137 | MP0003115_abnormal_respiratory_system | 0.74785483 |
| 138 | MP0001502_abnormal_circadian_rhythm | 0.74397602 |
| 139 | MP0004859_abnormal_synaptic_plasticity | 0.74248415 |
| 140 | MP0004883_abnormal_blood_vessel | 0.73664601 |
| 141 | MP0000631_abnormal_neuroendocrine_gland | 0.73360778 |
| 142 | MP0000470_abnormal_stomach_morphology | 0.71959113 |
| 143 | MP0004264_abnormal_extraembryonic_tissu | 0.71938372 |
| 144 | MP0005381_digestive/alimentary_phenotyp | 0.71757435 |
| 145 | MP0002102_abnormal_ear_morphology | 0.71327294 |
| 146 | MP0000026_abnormal_inner_ear | 0.71105261 |
| 147 | MP0001485_abnormal_pinna_reflex | 0.70942415 |
| 148 | MP0003186_abnormal_redox_activity | 0.70526407 |
| 149 | MP0004270_analgesia | 0.70179339 |
| 150 | MP0009115_abnormal_fat_cell | 0.69797429 |
| 151 | MP0002896_abnormal_bone_mineralization | 0.69459738 |
| 152 | MP0001944_abnormal_pancreas_morphology | 0.69021746 |
| 153 | MP0010234_abnormal_vibrissa_follicle | 0.68925847 |
| 154 | MP0003880_abnormal_central_pattern | 0.65943575 |
| 155 | MP0003633_abnormal_nervous_system | 0.65399795 |
| 156 | MP0001663_abnormal_digestive_system | 0.63567129 |
| 157 | MP0001943_abnormal_respiration | 0.63060569 |
| 158 | MP0001664_abnormal_digestion | 0.62865702 |
| 159 | MP0003045_fibrosis | 0.62816214 |
| 160 | MP0000467_abnormal_esophagus_morphology | 0.62354644 |
| 161 | MP0002971_abnormal_brown_adipose | 0.62104577 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 8.40450400 |
| 2 | Absent/shortened dynein arms (HP:0200106) | 8.40450400 |
| 3 | Chronic bronchitis (HP:0004469) | 7.07537431 |
| 4 | Bronchiectasis (HP:0002110) | 6.32512959 |
| 5 | Recurrent sinusitis (HP:0011108) | 4.81118620 |
| 6 | Nasal polyposis (HP:0100582) | 4.61490863 |
| 7 | Pancreatic fibrosis (HP:0100732) | 4.48922413 |
| 8 | True hermaphroditism (HP:0010459) | 4.40834014 |
| 9 | Chronic sinusitis (HP:0011109) | 4.29061831 |
| 10 | Abnormality of the nasal mucosa (HP:0000433) | 4.09736578 |
| 11 | Bronchitis (HP:0012387) | 3.79327270 |
| 12 | Nephronophthisis (HP:0000090) | 3.39324459 |
| 13 | Neoplasm of head and neck (HP:0012288) | 3.01993406 |
| 14 | Esophageal neoplasm (HP:0100751) | 3.01993406 |
| 15 | Occipital encephalocele (HP:0002085) | 2.98721798 |
| 16 | Pancreatic cysts (HP:0001737) | 2.98047086 |
| 17 | Median cleft lip (HP:0000161) | 2.81424302 |
| 18 | Gait imbalance (HP:0002141) | 2.71195106 |
| 19 | Congenital primary aphakia (HP:0007707) | 2.65823264 |
| 20 | Abnormality of the renal medulla (HP:0100957) | 2.61000067 |
| 21 | Congenital hepatic fibrosis (HP:0002612) | 2.60520176 |
| 22 | Infertility (HP:0000789) | 2.56427468 |
| 23 | Cystic liver disease (HP:0006706) | 2.56405198 |
| 24 | Medial flaring of the eyebrow (HP:0010747) | 2.51150232 |
| 25 | Tubular atrophy (HP:0000092) | 2.49203074 |
| 26 | Recurrent otitis media (HP:0000403) | 2.43918949 |
| 27 | Postaxial foot polydactyly (HP:0001830) | 2.40658439 |
| 28 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.37321191 |
| 29 | Nephrogenic diabetes insipidus (HP:0009806) | 2.31106777 |
| 30 | Abnormality of midbrain morphology (HP:0002418) | 2.30493186 |
| 31 | Molar tooth sign on MRI (HP:0002419) | 2.30493186 |
| 32 | Tubulointerstitial nephritis (HP:0001970) | 2.29620901 |
| 33 | Neonatal short-limb short stature (HP:0008921) | 2.25073493 |
| 34 | Bile duct proliferation (HP:0001408) | 2.13389635 |
| 35 | Abnormal biliary tract physiology (HP:0012439) | 2.13389635 |
| 36 | Supernumerary spleens (HP:0009799) | 2.12998184 |
| 37 | Genital tract atresia (HP:0001827) | 2.09676065 |
| 38 | Hip dysplasia (HP:0001385) | 2.06395908 |
| 39 | Preaxial hand polydactyly (HP:0001177) | 2.00131158 |
| 40 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.00091078 |
| 41 | Bronchomalacia (HP:0002780) | 2.00018376 |
| 42 | Abnormal ciliary motility (HP:0012262) | 13.7324251 |
| 43 | Abnormal respiratory motile cilium physiology (HP:0012261) | 13.1097457 |
| 44 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 11.2228884 |
| 45 | Rhinitis (HP:0012384) | 10.3216245 |
| 46 | Abnormal respiratory epithelium morphology (HP:0012253) | 10.2429260 |
| 47 | Abnormal respiratory motile cilium morphology (HP:0005938) | 10.2429260 |
| 48 | Chronic otitis media (HP:0000389) | 1.98312237 |
| 49 | Sclerocornea (HP:0000647) | 1.96675276 |
| 50 | Male pseudohermaphroditism (HP:0000037) | 1.94750787 |
| 51 | Decreased central vision (HP:0007663) | 1.94586695 |
| 52 | Hyperventilation (HP:0002883) | 1.92947072 |
| 53 | Facial cleft (HP:0002006) | 1.92605092 |
| 54 | Vaginal atresia (HP:0000148) | 1.92248483 |
| 55 | Atelectasis (HP:0100750) | 1.92242098 |
| 56 | Abnormality of dentin (HP:0010299) | 1.87578800 |
| 57 | Anencephaly (HP:0002323) | 1.87111285 |
| 58 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.87093847 |
| 59 | Tubulointerstitial abnormality (HP:0001969) | 1.86366079 |
| 60 | Poor coordination (HP:0002370) | 1.84746793 |
| 61 | Tubulointerstitial fibrosis (HP:0005576) | 1.84474229 |
| 62 | Stage 5 chronic kidney disease (HP:0003774) | 1.84387595 |
| 63 | Absent speech (HP:0001344) | 1.81886293 |
| 64 | Broad foot (HP:0001769) | 1.79946710 |
| 65 | Sex reversal (HP:0012245) | 1.76941341 |
| 66 | Abnormal sex determination (HP:0012244) | 1.76941341 |
| 67 | Narrow forehead (HP:0000341) | 1.72366911 |
| 68 | Aganglionic megacolon (HP:0002251) | 1.69143390 |
| 69 | Chronic hepatic failure (HP:0100626) | 1.68692906 |
| 70 | Prominent nasal bridge (HP:0000426) | 1.67992659 |
| 71 | Onycholysis (HP:0001806) | 1.65877002 |
| 72 | Congenital stationary night blindness (HP:0007642) | 1.65831884 |
| 73 | Postaxial hand polydactyly (HP:0001162) | 1.65815858 |
| 74 | Broad-based gait (HP:0002136) | 1.64514264 |
| 75 | Furrowed tongue (HP:0000221) | 1.64452419 |
| 76 | Abnormality of macular pigmentation (HP:0008002) | 1.61670565 |
| 77 | Recurrent bronchitis (HP:0002837) | 1.60520496 |
| 78 | Fibular hypoplasia (HP:0003038) | 1.60274898 |
| 79 | Hyperactive renin-angiotensin system (HP:0000841) | 1.59283606 |
| 80 | Abnormality of the renal cortex (HP:0011035) | 1.54983188 |
| 81 | Abolished electroretinogram (ERG) (HP:0000550) | 1.54514530 |
| 82 | Aplasia/Hypoplasia of the lens (HP:0008063) | 1.54497370 |
| 83 | Nephropathy (HP:0000112) | 1.52850078 |
| 84 | Progressive cerebellar ataxia (HP:0002073) | 1.51622736 |
| 85 | Multicystic kidney dysplasia (HP:0000003) | 1.51171594 |
| 86 | Asplenia (HP:0001746) | 1.49457772 |
| 87 | Polyuria (HP:0000103) | 1.46253138 |
| 88 | Attenuation of retinal blood vessels (HP:0007843) | 1.44994070 |
| 89 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.40760587 |
| 90 | Decreased testicular size (HP:0008734) | 1.39818934 |
| 91 | Highly arched eyebrow (HP:0002553) | 1.39577554 |
| 92 | Renal salt wasting (HP:0000127) | 1.38458442 |
| 93 | Fetal akinesia sequence (HP:0001989) | 1.36135096 |
| 94 | Concave nail (HP:0001598) | 1.34325660 |
| 95 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.33270008 |
| 96 | Astigmatism (HP:0000483) | 1.31936778 |
| 97 | Abnormality of the dental root (HP:0006486) | 1.31497524 |
| 98 | Taurodontia (HP:0000679) | 1.31497524 |
| 99 | Abnormality of permanent molar morphology (HP:0011071) | 1.31497524 |
| 100 | Oculomotor apraxia (HP:0000657) | 1.30820164 |
| 101 | Respiratory distress (HP:0002098) | 1.30657582 |
| 102 | Hypotelorism (HP:0000601) | 1.29666568 |
| 103 | Back pain (HP:0003418) | 1.29532815 |
| 104 | Dandy-Walker malformation (HP:0001305) | 1.28813663 |
| 105 | Femoral bowing (HP:0002980) | 1.28537767 |
| 106 | Central scotoma (HP:0000603) | 1.28357040 |
| 107 | 11 pairs of ribs (HP:0000878) | 1.28250538 |
| 108 | Gaze-evoked nystagmus (HP:0000640) | 1.27802944 |
| 109 | Hyperkalemia (HP:0002153) | 1.27597160 |
| 110 | Left ventricular hypertrophy (HP:0001712) | 1.27485379 |
| 111 | Specific learning disability (HP:0001328) | 1.27454019 |
| 112 | Tented upper lip vermilion (HP:0010804) | 1.26626916 |
| 113 | Abnormality of the dental pulp (HP:0006479) | 1.24301086 |
| 114 | Male infertility (HP:0003251) | 1.23930574 |
| 115 | Abnormality of abdominal situs (HP:0011620) | 1.23718010 |
| 116 | Abdominal situs inversus (HP:0003363) | 1.23718010 |
| 117 | Tachypnea (HP:0002789) | 1.23556039 |
| 118 | Hypodontia (HP:0000668) | 1.22957651 |
| 119 | Abnormality of renin-angiotensin system (HP:0000847) | 1.22333724 |
| 120 | Hepatocellular necrosis (HP:0001404) | 1.22281933 |
| 121 | Hyperaldosteronism (HP:0000859) | 1.21957856 |
| 122 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 1.20127548 |
| 123 | Ectopic anus (HP:0004397) | 1.17447849 |
| 124 | Abnormality of molar (HP:0011077) | 1.17227779 |
| 125 | Abnormality of molar morphology (HP:0011070) | 1.17227779 |
| 126 | Polycystic kidney dysplasia (HP:0000113) | 1.16506043 |
| 127 | Bifid tongue (HP:0010297) | 1.16316774 |
| 128 | Decreased circulating renin level (HP:0003351) | 1.15935726 |
| 129 | Polydipsia (HP:0001959) | 1.15098742 |
| 130 | Abnormal drinking behavior (HP:0030082) | 1.15098742 |
| 131 | Aplasia/Hypoplasia of the scapulae (HP:0006713) | 1.13910275 |
| 132 | Hypoplastic scapulae (HP:0000882) | 1.13910275 |
| 133 | Papilledema (HP:0001085) | 1.13780812 |
| 134 | Asthma (HP:0002099) | 1.13204096 |
| 135 | Omphalocele (HP:0001539) | 1.12677000 |
| 136 | Retinitis pigmentosa (HP:0000510) | 1.09064961 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAPK15 | 6.69746059 |
| 2 | PNCK | 6.28372843 |
| 3 | MST4 | 5.19199412 |
| 4 | MAP4K2 | 3.80367535 |
| 5 | MKNK2 | 3.35843360 |
| 6 | MAP3K4 | 2.95278038 |
| 7 | WNK3 | 2.68032815 |
| 8 | ARAF | 2.21504615 |
| 9 | DAPK2 | 2.14283560 |
| 10 | MAPK13 | 2.12060540 |
| 11 | BRSK2 | 2.11813538 |
| 12 | MAP2K7 | 2.06391119 |
| 13 | GRK1 | 2.04462102 |
| 14 | STK10 | 1.94977473 |
| 15 | TRIM28 | 1.93069835 |
| 16 | BMPR1B | 1.91557104 |
| 17 | MUSK | 1.89363683 |
| 18 | BRD4 | 1.74273503 |
| 19 | MAP2K2 | 1.72903045 |
| 20 | TGFBR2 | 1.59036001 |
| 21 | MKNK1 | 1.56539947 |
| 22 | SIK1 | 1.43387171 |
| 23 | ADRBK2 | 1.41515359 |
| 24 | EPHA4 | 1.38336913 |
| 25 | MOS | 1.35469925 |
| 26 | GRK5 | 1.31957487 |
| 27 | INSRR | 1.28066818 |
| 28 | FES | 1.26166660 |
| 29 | CASK | 1.25894123 |
| 30 | PINK1 | 1.21366721 |
| 31 | GSK3A | 1.20584719 |
| 32 | STK16 | 1.17928621 |
| 33 | NME1 | 1.16004207 |
| 34 | TIE1 | 1.15798447 |
| 35 | BLK | 1.14234465 |
| 36 | GRK7 | 1.12127905 |
| 37 | NUAK1 | 1.11651585 |
| 38 | IRAK1 | 1.09944442 |
| 39 | PAK2 | 1.09205829 |
| 40 | MAP3K2 | 1.09049887 |
| 41 | RPS6KA2 | 1.07729036 |
| 42 | DYRK2 | 1.07299384 |
| 43 | MAPKAPK3 | 1.06938439 |
| 44 | TLK1 | 1.06714703 |
| 45 | MARK3 | 1.03778899 |
| 46 | MAPKAPK5 | 1.02835631 |
| 47 | LRRK2 | 1.02044401 |
| 48 | TAOK3 | 1.01685231 |
| 49 | NTRK2 | 1.00872574 |
| 50 | DYRK3 | 1.00389776 |
| 51 | MAP2K4 | 0.99183116 |
| 52 | TRPM7 | 0.99020180 |
| 53 | WNK4 | 0.98678739 |
| 54 | RPS6KA4 | 0.98521541 |
| 55 | MAP3K7 | 0.97047418 |
| 56 | PTK2B | 0.96055478 |
| 57 | PIM2 | 0.96034287 |
| 58 | FER | 0.95809154 |
| 59 | ROCK2 | 0.95044547 |
| 60 | SIK3 | 0.92691363 |
| 61 | MYLK | 0.89503255 |
| 62 | ROCK1 | 0.88616110 |
| 63 | LMTK2 | 0.83983690 |
| 64 | ZAK | 0.83871302 |
| 65 | PAK3 | 0.83805538 |
| 66 | FLT3 | 0.82934952 |
| 67 | ERBB3 | 0.82415449 |
| 68 | IRAK2 | 0.81138957 |
| 69 | CAMKK2 | 0.80586350 |
| 70 | OBSCN | 0.80468361 |
| 71 | PTK6 | 0.77213260 |
| 72 | AURKA | 0.75977946 |
| 73 | STK39 | 0.74989662 |
| 74 | CSK | 0.74139037 |
| 75 | PKN1 | 0.72478293 |
| 76 | DYRK1A | 0.72224098 |
| 77 | ITK | 0.72076746 |
| 78 | ACVR1B | 0.71649584 |
| 79 | TEC | 0.71516102 |
| 80 | EPHA3 | 0.71378927 |
| 81 | OXSR1 | 0.70116512 |
| 82 | RPS6KC1 | 0.68558516 |
| 83 | RPS6KL1 | 0.68558516 |
| 84 | SIK2 | 0.68460081 |
| 85 | DYRK1B | 0.68397369 |
| 86 | CAMK2B | 0.67234452 |
| 87 | MINK1 | 0.67013685 |
| 88 | CSNK1G2 | 0.66688304 |
| 89 | PRKCH | 0.66273847 |
| 90 | SGK494 | 0.63655669 |
| 91 | SGK223 | 0.63655669 |
| 92 | BCKDK | 0.61361807 |
| 93 | CSNK1G1 | 0.60988778 |
| 94 | RPS6KA5 | 0.59503732 |
| 95 | FRK | 0.57774921 |
| 96 | CCNB1 | 0.57615072 |
| 97 | ADRBK1 | 0.56503767 |
| 98 | MAPKAPK2 | 0.56399736 |
| 99 | VRK1 | 0.54923337 |
| 100 | PRKCE | 0.54120419 |
| 101 | NLK | 0.53224426 |
| 102 | PRKG2 | 0.52446961 |
| 103 | CAMKK1 | 0.52262915 |
| 104 | PLK1 | 0.52150153 |
| 105 | PRKG1 | 0.51987804 |
| 106 | PTK2 | 0.51861125 |
| 107 | RPS6KA6 | 0.51529815 |
| 108 | PRKCQ | 0.50490263 |
| 109 | CAMK2G | 0.49945636 |
| 110 | PRKCZ | 0.49255795 |
| 111 | NTRK3 | 0.48898983 |
| 112 | ATR | 0.48707565 |
| 113 | TXK | 0.47930505 |
| 114 | HIPK2 | 0.47647963 |
| 115 | ERBB2 | 0.45786572 |
| 116 | CSNK1A1L | 0.45026469 |
| 117 | MAPK12 | 0.44222691 |
| 118 | BCR | 0.43681021 |
| 119 | PRKCG | 0.42913549 |
| 120 | SRC | 0.42485587 |
| 121 | SGK2 | 0.42113423 |
| 122 | STK24 | 0.41963184 |
| 123 | PRKAA1 | 0.41695590 |
| 124 | PRKCI | 0.41324875 |
| 125 | CSNK1G3 | 0.41316863 |
| 126 | WEE1 | 0.41292499 |
| 127 | BMPR2 | 0.40938120 |
| 128 | CDK3 | 0.40692364 |
| 129 | ATM | 0.40601314 |
| 130 | EIF2AK3 | 0.40273752 |
| 131 | PRKAA2 | 0.40063428 |
| 132 | TNK2 | 0.39937488 |
| 133 | MARK1 | 0.39479393 |
| 134 | EPHA2 | 0.39214681 |
| 135 | CAMK4 | 0.39114218 |
| 136 | PRKACA | 0.39009463 |
| 137 | TNIK | 0.38349340 |
| 138 | PRKACB | 0.38135741 |
| 139 | MAP2K1 | 0.37957783 |
| 140 | AKT2 | 0.37563628 |
| 141 | CAMK2A | 0.37223171 |
| 142 | STK11 | 0.36787008 |
| 143 | CAMK1 | 0.36760541 |
| 144 | PLK4 | 0.36719585 |
| 145 | FYN | 0.36687694 |
| 146 | MATK | 0.36595224 |
| 147 | PLK2 | 0.36267876 |
| 148 | CSNK1E | 0.35727550 |
| 149 | ABL1 | 0.35339836 |
| 150 | RPS6KB1 | 0.34450574 |
| 151 | UHMK1 | 0.34200463 |
| 152 | FGFR2 | 0.33916238 |
| 153 | SGK1 | 0.33728481 |
| 154 | NEK6 | 0.32851625 |
| 155 | PDK2 | 0.31897055 |
| 156 | PRKACG | 0.30549306 |
| 157 | EGFR | 0.29623394 |
| 158 | PHKG1 | 0.28040635 |
| 159 | PHKG2 | 0.28040635 |
| 160 | DAPK3 | 0.27531225 |
| 161 | CDK5 | 0.27402148 |
| 162 | MAP3K9 | 0.26368297 |
| 163 | CAMK2D | 0.24673585 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 3.09769447 |
| 2 | Huntingtons disease_Homo sapiens_hsa05016 | 2.76386498 |
| 3 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 2.71433281 |
| 4 | Histidine metabolism_Homo sapiens_hsa00340 | 2.55815081 |
| 5 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 2.50364098 |
| 6 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 2.46273426 |
| 7 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 2.30225070 |
| 8 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.28882396 |
| 9 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.22030114 |
| 10 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.21386559 |
| 11 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.96131524 |
| 12 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.88620547 |
| 13 | Circadian rhythm_Homo sapiens_hsa04710 | 1.84677085 |
| 14 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.81507127 |
| 15 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.80948953 |
| 16 | Taste transduction_Homo sapiens_hsa04742 | 1.79992669 |
| 17 | GABAergic synapse_Homo sapiens_hsa04727 | 1.70708650 |
| 18 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.56890343 |
| 19 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.53126722 |
| 20 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.52614795 |
| 21 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.50826627 |
| 22 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.47023083 |
| 23 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.42715970 |
| 24 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.42056862 |
| 25 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.38462038 |
| 26 | Nicotine addiction_Homo sapiens_hsa05033 | 1.38143732 |
| 27 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.34268178 |
| 28 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.34225611 |
| 29 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.33996989 |
| 30 | Insulin secretion_Homo sapiens_hsa04911 | 1.32987319 |
| 31 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.32230125 |
| 32 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.31875531 |
| 33 | Circadian entrainment_Homo sapiens_hsa04713 | 1.30838736 |
| 34 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.29197859 |
| 35 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.28692275 |
| 36 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.26677988 |
| 37 | Olfactory transduction_Homo sapiens_hsa04740 | 1.26544197 |
| 38 | Salivary secretion_Homo sapiens_hsa04970 | 1.25146193 |
| 39 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 1.24446591 |
| 40 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.22125292 |
| 41 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.21351210 |
| 42 | Retinol metabolism_Homo sapiens_hsa00830 | 1.16254012 |
| 43 | Homologous recombination_Homo sapiens_hsa03440 | 1.13296284 |
| 44 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.12932328 |
| 45 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.12831554 |
| 46 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.12010568 |
| 47 | Cocaine addiction_Homo sapiens_hsa05030 | 1.08937409 |
| 48 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.08466869 |
| 49 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.08317120 |
| 50 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.05707712 |
| 51 | Basal transcription factors_Homo sapiens_hsa03022 | 1.04013262 |
| 52 | Renin secretion_Homo sapiens_hsa04924 | 1.03737097 |
| 53 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.03692140 |
| 54 | Protein export_Homo sapiens_hsa03060 | 1.01911246 |
| 55 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.01874793 |
| 56 | Alzheimers disease_Homo sapiens_hsa05010 | 1.01543108 |
| 57 | Melanogenesis_Homo sapiens_hsa04916 | 0.97370948 |
| 58 | Asthma_Homo sapiens_hsa05310 | 0.96588078 |
| 59 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.95380413 |
| 60 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.94998943 |
| 61 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.94405782 |
| 62 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.90875320 |
| 63 | Morphine addiction_Homo sapiens_hsa05032 | 0.90658259 |
| 64 | Bile secretion_Homo sapiens_hsa04976 | 0.88364497 |
| 65 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.87230252 |
| 66 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.85323489 |
| 67 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.85200125 |
| 68 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.84967528 |
| 69 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.84601773 |
| 70 | Phototransduction_Homo sapiens_hsa04744 | 0.84449111 |
| 71 | RNA degradation_Homo sapiens_hsa03018 | 0.83363123 |
| 72 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.81976449 |
| 73 | Parkinsons disease_Homo sapiens_hsa05012 | 0.81974719 |
| 74 | Prion diseases_Homo sapiens_hsa05020 | 0.80887283 |
| 75 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.80176416 |
| 76 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.78503045 |
| 77 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.78241957 |
| 78 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.78043655 |
| 79 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.77131006 |
| 80 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.76345405 |
| 81 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.74831367 |
| 82 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.74304047 |
| 83 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.74234501 |
| 84 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.73938034 |
| 85 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.73826979 |
| 86 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.73484528 |
| 87 | Peroxisome_Homo sapiens_hsa04146 | 0.73188166 |
| 88 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.72854522 |
| 89 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.72831735 |
| 90 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.71329687 |
| 91 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.70956114 |
| 92 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.70110458 |
| 93 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.70009197 |
| 94 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.69853036 |
| 95 | Gap junction_Homo sapiens_hsa04540 | 0.69050061 |
| 96 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.69002026 |
| 97 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.68825372 |
| 98 | Phagosome_Homo sapiens_hsa04145 | 0.68376764 |
| 99 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.68186374 |
| 100 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.68090511 |
| 101 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.66924379 |
| 102 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.66006999 |
| 103 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.64741679 |
| 104 | Long-term potentiation_Homo sapiens_hsa04720 | 0.62597077 |
| 105 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.62153124 |
| 106 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.61819599 |
| 107 | Metabolic pathways_Homo sapiens_hsa01100 | 0.60481411 |
| 108 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.58871192 |
| 109 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.58784981 |
| 110 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.58017089 |
| 111 | ABC transporters_Homo sapiens_hsa02010 | 0.58008657 |
| 112 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.56945566 |
| 113 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.56938671 |
| 114 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.56620684 |
| 115 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.56603454 |
| 116 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.56525770 |
| 117 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.56122577 |
| 118 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.55804284 |
| 119 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.55184096 |
| 120 | Mineral absorption_Homo sapiens_hsa04978 | 0.54858833 |
| 121 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.54266831 |
| 122 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.53874151 |
| 123 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.53552819 |
| 124 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.53333724 |
| 125 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.53320513 |
| 126 | Tight junction_Homo sapiens_hsa04530 | 0.50829374 |
| 127 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.50315212 |
| 128 | Axon guidance_Homo sapiens_hsa04360 | 0.49372764 |
| 129 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.48367667 |
| 130 | RNA polymerase_Homo sapiens_hsa03020 | 0.48272550 |
| 131 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.47838582 |
| 132 | Purine metabolism_Homo sapiens_hsa00230 | 0.47112914 |
| 133 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.47111883 |
| 134 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.45056224 |
| 135 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.43516175 |
| 136 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.43239594 |
| 137 | Allograft rejection_Homo sapiens_hsa05330 | 0.43000710 |
| 138 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.42960464 |
| 139 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.41651599 |
| 140 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.41347370 |
| 141 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.36933938 |
| 142 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.33844904 |
| 143 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.31393366 |
| 144 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.29912259 |

