NMRK2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of skeletal muscle contraction (GO:0014819)7.80124083
2sarcomere organization (GO:0045214)7.76563463
3muscle filament sliding (GO:0030049)7.70245558
4actin-myosin filament sliding (GO:0033275)7.70245558
5actin-mediated cell contraction (GO:0070252)6.76109262
6myofibril assembly (GO:0030239)6.75373854
7positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)6.73515475
8regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)6.41898576
9sarcoplasmic reticulum calcium ion transport (GO:0070296)6.39569776
10cardiac myofibril assembly (GO:0055003)6.28469715
11regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO5.96761800
12regulation of relaxation of muscle (GO:1901077)5.76581690
13response to stimulus involved in regulation of muscle adaptation (GO:0014874)5.71781539
14NADH metabolic process (GO:0006734)5.34673410
15regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)5.33061001
16cardiac muscle contraction (GO:0060048)5.24116726
17skeletal muscle contraction (GO:0003009)5.20150721
18striated muscle contraction (GO:0006941)5.17626024
19regulation of actin filament-based movement (GO:1903115)5.15734779
20cardiac muscle hypertrophy (GO:0003300)5.15496511
21regulation of cell communication by electrical coupling (GO:0010649)5.07996966
22actomyosin structure organization (GO:0031032)5.01183928
23striated muscle hypertrophy (GO:0014897)4.93580806
24actin filament-based movement (GO:0030048)4.91475660
25cardiac muscle tissue morphogenesis (GO:0055008)4.91371344
26regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)4.82000344
27regulation of striated muscle contraction (GO:0006942)4.66776322
28cardiac muscle cell development (GO:0055013)4.65667570
29regulation of sarcomere organization (GO:0060297)4.58946443
30tricarboxylic acid cycle (GO:0006099)4.47055872
31muscle tissue morphogenesis (GO:0060415)4.46440724
32muscle hypertrophy (GO:0014896)4.45097975
33negative regulation of potassium ion transmembrane transporter activity (GO:1901017)4.44904341
34plasma membrane repair (GO:0001778)4.39067572
35cardiac cell development (GO:0055006)4.38923887
36adult heart development (GO:0007512)4.38776523
37response to inactivity (GO:0014854)4.17408068
38ventricular cardiac muscle cell action potential (GO:0086005)4.12512398
39ventricular cardiac muscle cell development (GO:0055015)4.12060865
40bundle of His cell to Purkinje myocyte communication (GO:0086069)4.11299969
41negative regulation of protein localization to cell surface (GO:2000009)4.01393657
42ventricular cardiac muscle tissue morphogenesis (GO:0055010)3.97191232
43fatty acid transmembrane transport (GO:1902001)3.96198447
44regulation of ATP catabolic process (GO:1903289)3.95464406
45regulation of ATPase activity (GO:0043462)3.95464406
46mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.90002591
47heart contraction (GO:0060047)3.88801344
48heart process (GO:0003015)3.88801344
49regulation of cardiac muscle contraction (GO:0055117)3.81914539
50detection of calcium ion (GO:0005513)3.74252686
51negative regulation of potassium ion transmembrane transport (GO:1901380)3.71350017
52regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)3.71288507
53skeletal muscle adaptation (GO:0043501)3.66585555
542-oxoglutarate metabolic process (GO:0006103)3.60585074
55negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)3.58890495
56negative regulation of muscle hypertrophy (GO:0014741)3.55710419
57regulation of membrane repolarization (GO:0060306)3.55117826
58positive regulation of action potential (GO:0045760)3.53680974
59cardiac muscle cell action potential (GO:0086001)3.52284723
60response to muscle activity (GO:0014850)3.50104211
61carnitine transmembrane transport (GO:1902603)3.49421899
62muscle contraction (GO:0006936)3.48552563
63positive regulation of calcium ion transmembrane transporter activity (GO:1901021)3.47840317
64membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.46375428
65skeletal muscle fiber development (GO:0048741)3.45177776
66relaxation of cardiac muscle (GO:0055119)3.44700464
67regulation of cardioblast differentiation (GO:0051890)3.41333107
68muscle cell development (GO:0055001)3.41212649
69heart trabecula formation (GO:0060347)3.40967062
70regulation of action potential (GO:0098900)3.33962393
71cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.31875988
72glycogen biosynthetic process (GO:0005978)3.31573649
73glucan biosynthetic process (GO:0009250)3.31573649
74negative regulation of calcium ion transmembrane transport (GO:1903170)3.31195796
75negative regulation of calcium ion transmembrane transporter activity (GO:1901020)3.31195796
76muscle system process (GO:0003012)3.30201154
77striated muscle adaptation (GO:0014888)3.29161671
78response to caffeine (GO:0031000)3.29148592
79positive regulation of heart rate (GO:0010460)3.25690764
80carnitine shuttle (GO:0006853)3.25364310
81neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)3.25017381
82regulation of cardiac muscle cell contraction (GO:0086004)3.24815555
83aspartate family amino acid catabolic process (GO:0009068)3.24693119
84myotube cell development (GO:0014904)3.23917727
85regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.23738175
86negative regulation of cardiac muscle hypertrophy (GO:0010614)3.23629308
87muscle fiber development (GO:0048747)3.23173545
88regulation of heart rate (GO:0002027)3.22469958
89regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)3.22317533
90striated muscle cell development (GO:0055002)3.21515627
91regulation of muscle contraction (GO:0006937)3.21361302
92positive regulation of cation channel activity (GO:2001259)3.20590939
93cell communication involved in cardiac conduction (GO:0086065)3.20590633
94cardiac muscle cell action potential involved in contraction (GO:0086002)3.20483069
95mitochondrial genome maintenance (GO:0000002)3.19746430
96response to epinephrine (GO:0071871)3.18577780
97oxidative phosphorylation (GO:0006119)3.17876264
98cardiac muscle hypertrophy in response to stress (GO:0014898)3.16869486
99muscle hypertrophy in response to stress (GO:0003299)3.16869486
100cardiac muscle adaptation (GO:0014887)3.16869486
101cardiac chamber formation (GO:0003207)3.15599040
102regulation of the force of heart contraction (GO:0002026)3.12380705
103respiratory electron transport chain (GO:0022904)3.08460951
104cardiac conduction (GO:0061337)3.08070511
105regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.03160603
106regulation of acyl-CoA biosynthetic process (GO:0050812)3.02630166
107regulation of muscle system process (GO:0090257)2.99840240
108striated muscle atrophy (GO:0014891)2.99838379
109electron transport chain (GO:0022900)2.97575069
110muscle cell cellular homeostasis (GO:0046716)2.94171652
111cellular response to epinephrine stimulus (GO:0071872)2.93089153
112regulation of calcium ion transmembrane transport (GO:1903169)2.92941670
113regulation of calcium ion transmembrane transporter activity (GO:1901019)2.92941670
114muscle atrophy (GO:0014889)2.92199907
115regulation of heart contraction (GO:0008016)2.91457867
116adrenergic receptor signaling pathway (GO:0071875)2.91214223
117regulation of cardiac muscle cell differentiation (GO:2000725)2.89242929
118muscle adaptation (GO:0043500)2.88210750
119creatine metabolic process (GO:0006600)2.86959761
120pyrimidine ribonucleoside catabolic process (GO:0046133)2.82741283
121positive regulation of microtubule polymerization (GO:0031116)2.82194299
122cell communication by electrical coupling (GO:0010644)2.81251155
123regulation of heart rate by cardiac conduction (GO:0086091)2.79095810
124negative regulation of cardiac muscle cell apoptotic process (GO:0010667)2.75968653

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human4.12529320
2EZH2_22144423_ChIP-Seq_EOC_Human4.09253789
3ESRRB_18555785_ChIP-Seq_MESCs_Mouse4.05540113
4PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.17794312
5GBX2_23144817_ChIP-Seq_PC3_Human3.17218940
6E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.89167143
7TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.78635641
8GATA4_21415370_ChIP-Seq_HL-1_Mouse2.73656667
9TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.63195502
10EP300_21415370_ChIP-Seq_HL-1_Mouse2.53522841
11NKX2-5_21415370_ChIP-Seq_HL-1_Mouse2.39316338
12GATA1_22025678_ChIP-Seq_K562_Human2.39291115
13ZFP57_27257070_Chip-Seq_ESCs_Mouse2.36931696
14FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.35461371
15GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.31752287
16ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.30163370
17PCGF2_27294783_Chip-Seq_ESCs_Mouse2.29263710
18VDR_22108803_ChIP-Seq_LS180_Human2.20948956
19CDX2_19796622_ChIP-Seq_MESCs_Mouse2.18078851
20PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.12818826
21PCGF2_27294783_Chip-Seq_NPCs_Mouse2.09757364
22NR0B1_18358816_ChIP-ChIP_MESCs_Mouse2.07164045
23EZH2_27304074_Chip-Seq_ESCs_Mouse1.97708190
24SUZ12_27294783_Chip-Seq_NPCs_Mouse1.97593400
25BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.96542307
26FLI1_27457419_Chip-Seq_LIVER_Mouse1.94890328
27RARG_19884340_ChIP-ChIP_MEFs_Mouse1.90810821
28NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.88788399
29TAF15_26573619_Chip-Seq_HEK293_Human1.84641424
30ZNF263_19887448_ChIP-Seq_K562_Human1.84635177
31POU3F2_20337985_ChIP-ChIP_501MEL_Human1.84409645
32CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.84102853
33CBX2_27304074_Chip-Seq_ESCs_Mouse1.83662152
34SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.80203308
35NFE2_27457419_Chip-Seq_LIVER_Mouse1.78187872
36PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.75194179
37SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.74153462
38JARID2_20064375_ChIP-Seq_MESCs_Mouse1.73062724
39PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.69513249
40BMI1_23680149_ChIP-Seq_NPCS_Mouse1.69469633
41CLOCK_20551151_ChIP-Seq_293T_Human1.67241807
42RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.67226245
43EZH2_27294783_Chip-Seq_NPCs_Mouse1.63052137
44EED_16625203_ChIP-ChIP_MESCs_Mouse1.63004744
45SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.59285037
46PIAS1_25552417_ChIP-Seq_VCAP_Human1.55609931
47E2F1_18555785_Chip-Seq_ESCs_Mouse1.55516443
48NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.55491570
49EZH2_27294783_Chip-Seq_ESCs_Mouse1.54839111
50SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.53742234
51EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.53205154
52SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.53136882
53DROSHA_22980978_ChIP-Seq_HELA_Human1.52544678
54SMAD4_21799915_ChIP-Seq_A2780_Human1.50040515
55TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.48856632
56STAT3_18555785_Chip-Seq_ESCs_Mouse1.48226619
57RNF2_18974828_ChIP-Seq_MESCs_Mouse1.48185438
58EZH2_18974828_ChIP-Seq_MESCs_Mouse1.48185438
59SUZ12_18555785_Chip-Seq_ESCs_Mouse1.47693298
60STAT3_1855785_ChIP-Seq_MESCs_Mouse1.46555473
61CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.46385298
62P53_22387025_ChIP-Seq_ESCs_Mouse1.46153081
63NANOG_18555785_Chip-Seq_ESCs_Mouse1.45925173
64ESR1_20079471_ChIP-ChIP_T-47D_Human1.45395814
65ER_23166858_ChIP-Seq_MCF-7_Human1.44114643
66PRDM14_21183938_ChIP-Seq_MESCs_Mouse1.43166954
67AR_21572438_ChIP-Seq_LNCaP_Human1.43007655
68EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.40458727
69MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.39866645
70DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.39717390
71P300_19829295_ChIP-Seq_ESCs_Human1.39595513
72POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.39497319
73TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.39497319
74SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.38673851
75SMAD_19615063_ChIP-ChIP_OVARY_Human1.36509350
76CTBP1_25329375_ChIP-Seq_LNCAP_Human1.36059071
77NFIB_24661679_ChIP-Seq_LUNG_Mouse1.35717081
78TCF3_18692474_ChIP-Seq_MEFs_Mouse1.35258850
79UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.34589330
80JARID2_20075857_ChIP-Seq_MESCs_Mouse1.33974028
81RNF2_27304074_Chip-Seq_ESCs_Mouse1.33415400
82SOX2_18555785_Chip-Seq_ESCs_Mouse1.33151288
83PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.31734187
84SMAD3_21741376_ChIP-Seq_EPCs_Human1.31598098
85SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.30545441
86RUNX1_27457419_Chip-Seq_LIVER_Mouse1.29768437
87P300_18555785_Chip-Seq_ESCs_Mouse1.29600554
88ZFX_18555785_Chip-Seq_ESCs_Mouse1.28218941
89CRX_20693478_ChIP-Seq_RETINA_Mouse1.27400522
90CMYC_18555785_Chip-Seq_ESCs_Mouse1.26763760
91TBX20_22080862_ChIP-Seq_HEART_Mouse1.26285217
92TBX20_22328084_ChIP-Seq_HEART_Mouse1.26285217
93FUS_26573619_Chip-Seq_HEK293_Human1.25001610
94NMYC_18555785_Chip-Seq_ESCs_Mouse1.24741904
95NR3C1_21868756_ChIP-Seq_MCF10A_Human1.23596820
96MTF2_20144788_ChIP-Seq_MESCs_Mouse1.23125319
97CTCF_27219007_Chip-Seq_Bcells_Human1.21106439
98SRF_21415370_ChIP-Seq_HL-1_Mouse1.20397625
99TCF3_18692474_ChIP-Seq_MESCs_Mouse1.20070805
100THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.19567488
101OCT4_18555785_Chip-Seq_ESCs_Mouse1.19509303
102SUZ12_27294783_Chip-Seq_ESCs_Mouse1.18341978
103TOP2B_26459242_ChIP-Seq_MCF-7_Human1.18135989
104CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.17507151
105ZFP281_18757296_ChIP-ChIP_E14_Mouse1.15686421
106PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.15507976
107ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.15381300
108TAL1_26923725_Chip-Seq_HPCs_Mouse1.14039354
109PU1_27457419_Chip-Seq_LIVER_Mouse1.13714936
110KLF4_18555785_Chip-Seq_ESCs_Mouse1.12906802
111OCT4_21477851_ChIP-Seq_ESCs_Mouse1.12764537
112ISL1_27105846_Chip-Seq_CPCs_Mouse1.12515903
113ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.12331929
114POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.12207344
115CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12127761
116TP53_18474530_ChIP-ChIP_U2OS_Human1.12059125
117CTCF_18555785_Chip-Seq_ESCs_Mouse1.11877416
118SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.11859060
119SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.10994917
120TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10871512
121LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.10243680
122TBL1_22424771_ChIP-Seq_293T_Human1.10169248
123SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.08733975
124PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.08151616
125MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.06215268
126SMAD3_21741376_ChIP-Seq_HESCs_Human1.05750006
127WT1_19549856_ChIP-ChIP_CCG9911_Human1.05272061
128RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.05245888
129HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.04710564
130TCF4_23295773_ChIP-Seq_U87_Human1.04383605
131TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.03628577
132TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.03363542
133SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.02574726
134RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.02488764
135AHR_22903824_ChIP-Seq_MCF-7_Human1.02351759
136CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.01315648
137SMC3_22415368_ChIP-Seq_MEFs_Mouse1.00953002
138EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.00250297
139NANOG_18692474_ChIP-Seq_MEFs_Mouse0.99361171
140THAP11_20581084_ChIP-Seq_MESCs_Mouse0.98723209
141NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.98004553
142SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.96599183
143EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.96062382
144NANOG_16153702_ChIP-ChIP_HESCs_Human0.94758821
145ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.94336038
146GATA1_19941827_ChIP-Seq_MEL86_Mouse0.93157282
147STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.92809604
148ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.91145809
149NANOG_21062744_ChIP-ChIP_HESCs_Human0.87714585
150SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.85447053
151OCT4_20526341_ChIP-Seq_ESCs_Human0.83522021
152NANOG_18692474_ChIP-Seq_MESCs_Mouse0.83496850
153GF1_26923725_Chip-Seq_HPCs_Mouse0.80997674
154GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.80479940
155CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.77670739
156FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.77472926
157PPARA_22158963_ChIP-Seq_LIVER_Mouse0.76966431
158NR3C1_23031785_ChIP-Seq_PC12_Mouse0.76524181
159SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.76468314
160CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.75845908
161SALL4_18804426_ChIP-ChIP_XEN_Mouse0.75607382
162RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.75236551
163SOX2_18692474_ChIP-Seq_MEFs_Mouse0.74101909
164BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.74043616
165OCT4_18692474_ChIP-Seq_MEFs_Mouse0.73319861
166PHF8_20622853_ChIP-Seq_HELA_Human0.73046707
167TRIM28_21343339_ChIP-Seq_HEK293_Human0.72689592
168SMAD4_21741376_ChIP-Seq_HESCs_Human0.72665053
169LXR_22158963_ChIP-Seq_LIVER_Mouse0.72514865
170ESR2_21235772_ChIP-Seq_MCF-7_Human0.71838574
171RBPJ_22232070_ChIP-Seq_NCS_Mouse0.69510693
172POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.69207031
173HNFA_21074721_ChIP-Seq_CACO-2_Human0.68072590
174PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.67757845
175RBPJ_21746931_ChIP-Seq_IB4_Human0.67441152
176RXR_22158963_ChIP-Seq_LIVER_Mouse0.67347115
177KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.67236411
178KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.67236411
179KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.67236411

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002837_dystrophic_cardiac_calcinosis6.38862838
2MP0000751_myopathy5.36494012
3MP0003646_muscle_fatigue5.17240185
4MP0000749_muscle_degeneration4.82998429
5MP0004215_abnormal_myocardial_fiber4.24976634
6MP0004084_abnormal_cardiac_muscle4.12914293
7MP0004036_abnormal_muscle_relaxation3.67012208
8MP0004145_abnormal_muscle_electrophysio3.64754084
9MP0005330_cardiomyopathy3.22513057
10MP0002106_abnormal_muscle_physiology2.87128587
11MP0005620_abnormal_muscle_contractility2.80076788
12MP0003137_abnormal_impulse_conducting2.77637720
13MP0004087_abnormal_muscle_fiber2.75864236
14MP0002972_abnormal_cardiac_muscle2.65276874
15MP0004510_myositis2.50709629
16MP0000750_abnormal_muscle_regeneration2.46239557
17MP0005369_muscle_phenotype2.43092104
18MP0003950_abnormal_plasma_membrane2.41933887
19MP0008775_abnormal_heart_ventricle2.28309456
20MP0004484_altered_response_of2.23327985
21MP0000759_abnormal_skeletal_muscle2.15867115
22MP0003828_pulmonary_edema2.10502068
23MP0002269_muscular_atrophy1.98894116
24MP0000747_muscle_weakness1.98763415
25MP0001544_abnormal_cardiovascular_syste1.95154931
26MP0005385_cardiovascular_system_phenoty1.95154931
27MP0002127_abnormal_cardiovascular_syste1.93099256
28MP0010630_abnormal_cardiac_muscle1.90190040
29MP0004085_abnormal_heartbeat1.77020831
30MP0004130_abnormal_muscle_cell1.74531368
31MP0003221_abnormal_cardiomyocyte_apopto1.43582713
32MP0001188_hyperpigmentation1.40083929
33MP0006138_congestive_heart_failure1.35016225
34MP0002332_abnormal_exercise_endurance1.33823591
35MP0002108_abnormal_muscle_morphology1.27843950
36MP0005171_absent_coat_pigmentation1.25270114
37MP0005266_abnormal_metabolism1.15097848
38MP0006292_abnormal_olfactory_placode1.12350793
39MP0003941_abnormal_skin_development1.12144549
40MP0005646_abnormal_pituitary_gland1.11754129
41MP0000566_synostosis1.10844442
42MP0004233_abnormal_muscle_weight1.06613715
43MP0001986_abnormal_taste_sensitivity1.03511762
44MP0003136_yellow_coat_color0.99946016
45MP0002638_abnormal_pupillary_reflex0.98163620
46MP0006036_abnormal_mitochondrial_physio0.98046131
47MP0005409_darkened_coat_color0.96900266
48MP0005670_abnormal_white_adipose0.93196311
49MP0005645_abnormal_hypothalamus_physiol0.91947484
50MP0001661_extended_life_span0.91579700
51MP0005451_abnormal_body_composition0.91279204
52MP0000343_altered_response_to0.90593462
53MP0004142_abnormal_muscle_tone0.90006527
54MP0004381_abnormal_hair_follicle0.88962627
55MP0005666_abnormal_adipose_tissue0.87846014
56MP0000013_abnormal_adipose_tissue0.83143619
57MP0002254_reproductive_system_inflammat0.83063416
58MP0003279_aneurysm0.77880460
59MP0001529_abnormal_vocalization0.77249222
60MP0000372_irregular_coat_pigmentation0.76476504
61MP0005375_adipose_tissue_phenotype0.72651554
62MP0002822_catalepsy0.70394920
63MP0006276_abnormal_autonomic_nervous0.68314404
64MP0006035_abnormal_mitochondrial_morpho0.68014138
65MP0003045_fibrosis0.67983789
66MP0001984_abnormal_olfaction0.66868280
67MP0000733_abnormal_muscle_development0.66642664
68MP0005165_increased_susceptibility_to0.66525272
69MP0005187_abnormal_penis_morphology0.66168624
70MP0003806_abnormal_nucleotide_metabolis0.65150083
71MP0001299_abnormal_eye_distance/0.64137225
72MP0000266_abnormal_heart_morphology0.63994327
73MP0002102_abnormal_ear_morphology0.63608990
74MP0000230_abnormal_systemic_arterial0.60447115
75MP0005423_abnormal_somatic_nervous0.59926619
76MP0000003_abnormal_adipose_tissue0.56552829
77MP0009672_abnormal_birth_weight0.56501979
78MP0006072_abnormal_retinal_apoptosis0.56116173
79MP0001486_abnormal_startle_reflex0.54990364
80MP0003567_abnormal_fetal_cardiomyocyte0.54951264
81MP0001879_abnormal_lymphatic_vessel0.54559230
82MP0002735_abnormal_chemical_nociception0.54114082
83MP0002277_abnormal_respiratory_mucosa0.54105057
84MP0008995_early_reproductive_senescence0.53719242
85MP0005253_abnormal_eye_physiology0.49565738
86MP0002132_abnormal_respiratory_system0.49351223
87MP0000767_abnormal_smooth_muscle0.48376828
88MP0005379_endocrine/exocrine_gland_phen0.46167897
89MP0000015_abnormal_ear_pigmentation0.45269977
90MP0002148_abnormal_hypersensitivity_rea0.44809939
91MP0001727_abnormal_embryo_implantation0.44685475
92MP0010030_abnormal_orbit_morphology0.44630355
93MP0002938_white_spotting0.44532904
94MP0005551_abnormal_eye_electrophysiolog0.44448776
95MP0000579_abnormal_nail_morphology0.43217384
96MP0003880_abnormal_central_pattern0.42120942
97MP0004147_increased_porphyrin_level0.41454084
98MP0002067_abnormal_sensory_capabilities0.41270224
99MP0003724_increased_susceptibility_to0.41244651
100MP0000049_abnormal_middle_ear0.40858386
101MP0008260_abnormal_autophagy0.40768600
102MP0002128_abnormal_blood_circulation0.40380170
103MP0004185_abnormal_adipocyte_glucose0.40043753
104MP0009250_abnormal_appendicular_skeleto0.40003932
105MP0009745_abnormal_behavioral_response0.39411079
106MP0002971_abnormal_brown_adipose0.38832498
107MP0000762_abnormal_tongue_morphology0.38809454
108MP0010368_abnormal_lymphatic_system0.38098803
109MP0003948_abnormal_gas_homeostasis0.36944634
110MP0004924_abnormal_behavior0.36813307
111MP0005386_behavior/neurological_phenoty0.36813307
112MP0005623_abnormal_meninges_morphology0.36798929
113MP0000026_abnormal_inner_ear0.36546482
114MP0005503_abnormal_tendon_morphology0.36488597
115MP0008569_lethality_at_weaning0.33753310
116MP0004270_analgesia0.33663317
117MP0002090_abnormal_vision0.30389549
118MP0009384_cardiac_valve_regurgitation0.30167179
119MP0003984_embryonic_growth_retardation0.30138561
120MP0002088_abnormal_embryonic_growth/wei0.28966144
121MP0004272_abnormal_basement_membrane0.28202219
122MP0002078_abnormal_glucose_homeostasis0.27501511
123MP0009780_abnormal_chondrocyte_physiolo0.26157905
124MP0002234_abnormal_pharynx_morphology0.24535077
125MP0001730_embryonic_growth_arrest0.24136606
126MP0002925_abnormal_cardiovascular_devel0.23521634
127MP0005332_abnormal_amino_acid0.23026857
128MP0005584_abnormal_enzyme/coenzyme_acti0.22241311
129MP0005167_abnormal_blood-brain_barrier0.21601317
130MP0005376_homeostasis/metabolism_phenot0.21546235
131MP0005334_abnormal_fat_pad0.19371518
132MP0001672_abnormal_embryogenesis/_devel0.19333754
133MP0005380_embryogenesis_phenotype0.19333754
134MP0008004_abnormal_stomach_pH0.19295468
135MP0002295_abnormal_pulmonary_circulatio0.18247254
136MP0005319_abnormal_enzyme/_coenzyme0.17236343
137MP0001784_abnormal_fluid_regulation0.16638497

Predicted human phenotypes

RankGene SetZ-score
1Calf muscle hypertrophy (HP:0008981)6.92304208
2Sudden death (HP:0001699)6.91639235
3Muscle hypertrophy of the lower extremities (HP:0008968)6.78559411
4Muscle fiber splitting (HP:0003555)6.10487475
5Exercise-induced myalgia (HP:0003738)6.05102328
6Abnormality of the calf musculature (HP:0001430)5.67605975
7Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)5.56201126
8Muscle fiber inclusion bodies (HP:0100299)5.54867777
9Exercise-induced muscle cramps (HP:0003710)5.51013326
10Ventricular tachycardia (HP:0004756)5.44917729
11Atrial fibrillation (HP:0005110)5.11922592
12Hyporeflexia of lower limbs (HP:0002600)5.05979628
13Nemaline bodies (HP:0003798)4.90649813
14Primary atrial arrhythmia (HP:0001692)4.73569512
15EMG: myopathic abnormalities (HP:0003458)4.63056847
16Supraventricular tachycardia (HP:0004755)4.52378961
17Supraventricular arrhythmia (HP:0005115)4.39670276
18Lipoatrophy (HP:0100578)4.35261387
19Syncope (HP:0001279)4.12755363
20Right ventricular cardiomyopathy (HP:0011663)4.07846092
21Subaortic stenosis (HP:0001682)4.02593904
22Abnormality of the left ventricular outflow tract (HP:0011103)4.02593904
23Dilated cardiomyopathy (HP:0001644)3.93318100
24Prolonged QT interval (HP:0001657)3.71502342
25Type 1 muscle fiber predominance (HP:0003803)3.70796826
26Distal lower limb muscle weakness (HP:0009053)3.60540944
27Difficulty running (HP:0009046)3.51174728
28Increased connective tissue (HP:0009025)3.42483701
29Myoglobinuria (HP:0002913)3.37808282
30Neck muscle weakness (HP:0000467)3.16709555
31Ulnar deviation of the wrist (HP:0003049)3.13556593
32Rimmed vacuoles (HP:0003805)3.11963632
33Myotonia (HP:0002486)3.11448177
34Palpitations (HP:0001962)3.10009941
35Ragged-red muscle fibers (HP:0003200)3.05901789
36Bundle branch block (HP:0011710)3.03553939
37Ventricular arrhythmia (HP:0004308)2.98476541
38Round ear (HP:0100830)2.95728670
39Areflexia of lower limbs (HP:0002522)2.94695745
40Frequent falls (HP:0002359)2.89823347
41Distal lower limb amyotrophy (HP:0008944)2.87508692
42Abnormal EKG (HP:0003115)2.78264291
43Rhabdomyolysis (HP:0003201)2.71431458
44Left ventricular hypertrophy (HP:0001712)2.67692307
45Abnormality of the renal collecting system (HP:0004742)2.67229245
46Distal arthrogryposis (HP:0005684)2.63038013
47Deformed tarsal bones (HP:0008119)2.62010809
48Muscle stiffness (HP:0003552)2.61180911
49Abnormality of skeletal muscle fiber size (HP:0012084)2.58455836
50Acute necrotizing encephalopathy (HP:0006965)2.56928275
51Heart block (HP:0012722)2.56206042
52Limb-girdle muscle atrophy (HP:0003797)2.56018303
53Duplicated collecting system (HP:0000081)2.54799510
54Absent phalangeal crease (HP:0006109)2.49399825
55Progressive muscle weakness (HP:0003323)2.47679971
56Difficulty climbing stairs (HP:0003551)2.44510952
57Asymmetric septal hypertrophy (HP:0001670)2.42889964
58Abnormal atrioventricular conduction (HP:0005150)2.41424866
59Myopathic facies (HP:0002058)2.41063713
60Muscular dystrophy (HP:0003560)2.40355492
61Increased variability in muscle fiber diameter (HP:0003557)2.36551832
62Abnormal mitochondria in muscle tissue (HP:0008316)2.32956493
63Bulbar palsy (HP:0001283)2.32903009
64Testicular atrophy (HP:0000029)2.32691322
65Centrally nucleated skeletal muscle fibers (HP:0003687)2.30661324
66Proximal amyotrophy (HP:0007126)2.27378739
67Mitochondrial inheritance (HP:0001427)2.23702874
68Generalized muscle weakness (HP:0003324)2.20327704
69Gowers sign (HP:0003391)2.16675272
70Palmoplantar keratoderma (HP:0000982)2.16374518
71Chromosomal breakage induced by crosslinking agents (HP:0003221)2.15725375
72Progressive macrocephaly (HP:0004481)2.15237076
73Weak cry (HP:0001612)2.12203077
74Exercise intolerance (HP:0003546)2.11801025
75Lower limb amyotrophy (HP:0007210)2.08285056
76Abnormality of the shoulder girdle musculature (HP:0001435)2.06746776
77Steppage gait (HP:0003376)2.06678019
78Abnormality of the neuromuscular junction (HP:0003398)2.04516337
79Fatigable weakness (HP:0003473)2.04516337
80Bradycardia (HP:0001662)2.04304601
81Increased CSF lactate (HP:0002490)2.02497718
82Increased intramyocellular lipid droplets (HP:0012240)2.00473198
83Abnormal finger flexion creases (HP:0006143)2.00248199
84Abnormality of the foot musculature (HP:0001436)1.97831116
85Respiratory insufficiency due to muscle weakness (HP:0002747)1.96958484
86Foot dorsiflexor weakness (HP:0009027)1.95302229
87Mildly elevated creatine phosphokinase (HP:0008180)1.94817885
88Congenital malformation of the right heart (HP:0011723)1.91997947
89Double outlet right ventricle (HP:0001719)1.91997947
90Ventricular fibrillation (HP:0001663)1.91175253
91Hepatocellular necrosis (HP:0001404)1.84458168
92Hepatic necrosis (HP:0002605)1.84443420
93Increased muscle lipid content (HP:0009058)1.84328281
94Hyperkalemia (HP:0002153)1.82707825
95Abnormality of alanine metabolism (HP:0010916)1.82578146
96Hyperalaninemia (HP:0003348)1.82578146
97Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.82578146
98Hip contracture (HP:0003273)1.80918799
99Atrioventricular block (HP:0001678)1.80544629
100Fetal akinesia sequence (HP:0001989)1.80123682
101EMG: neuropathic changes (HP:0003445)1.77856605
102Acute encephalopathy (HP:0006846)1.77027366
103Malignant hyperthermia (HP:0002047)1.76849150
104Febrile seizures (HP:0002373)1.76212931
105Hypoplastic heart (HP:0001961)1.75341406
106Waddling gait (HP:0002515)1.74514036
107Optic disc pallor (HP:0000543)1.73853641
108Renal cortical cysts (HP:0000803)1.71203077
109Pulmonary artery stenosis (HP:0004415)1.69398276
110Facial diplegia (HP:0001349)1.68715345
111Toxemia of pregnancy (HP:0100603)1.68257633
112Hypoplastic ischia (HP:0003175)1.67482963
113Increased serum pyruvate (HP:0003542)1.66761736
114Calcaneovalgus deformity (HP:0001848)1.65851993
115Chromsome breakage (HP:0040012)1.65048991
116Scapular winging (HP:0003691)1.64561775
117Progressive external ophthalmoplegia (HP:0000590)1.64169557
118Increased hepatocellular lipid droplets (HP:0006565)1.64125947
119Spinal rigidity (HP:0003306)1.63200298
120Abnormality of glycolysis (HP:0004366)1.58858516
121Hypoplastic left heart (HP:0004383)1.56579690
122Limb-girdle muscle weakness (HP:0003325)1.55343346
123Abnormality of the calcaneus (HP:0008364)1.53678434
124Aplasia of the musculature (HP:0100854)1.52437247
125Slender build (HP:0001533)1.52332427
126Abnormality of the tricuspid valve (HP:0001702)1.49630175
127Sudden cardiac death (HP:0001645)1.49522612

Predicted kinase interactions (KEA)

RankGene SetZ-score
1OBSCN7.41190203
2ZAK4.16580355
3PHKG13.52099148
4PHKG23.52099148
5TTN3.22623476
6MUSK3.21362288
7INSRR2.77651833
8DMPK2.31874438
9GRK72.14413849
10CASK2.11746336
11NME11.93965764
12MYLK1.88056766
13PINK11.87855887
14PIK3CA1.84330290
15TIE11.78571685
16IRAK31.65887968
17PKN11.58377878
18PDK21.51848502
19TNIK1.46014189
20PDK41.43844760
21PDK31.43844760
22NEK11.42232706
23STK241.40885194
24PIK3CG1.38847971
25CAMK2D1.34093646
26EEF2K1.31289802
27TXK1.28324577
28STK161.28184306
29MAP3K141.24513637
30LMTK21.16174820
31TRPM71.14764054
32STK38L1.13994227
33MAPK121.07621448
34EIF2AK21.05494047
35IRAK41.00311812
36ADRBK20.99498786
37PRPF4B0.95345127
38PRKCE0.90471249
39MAP2K70.89486439
40BMPR20.82051476
41PRKAA20.81848877
42GRK10.79831733
43CAMK2A0.78689681
44NUAK10.78499014
45MAPK130.78370812
46NEK60.76208669
47SGK20.73207065
48BCKDK0.71249255
49CDC42BPA0.69299373
50YES10.68163626
51ERBB30.67393025
52IRAK10.65569414
53PRKD10.65036598
54AKT30.64697380
55MKNK20.64669656
56ROCK10.64215312
57MAP3K60.61899914
58STK390.61518821
59BMPR1B0.61228848
60SIK30.60112564
61EPHA30.58933558
62PRKG10.57843836
63RIPK10.56823029
64WNK10.55745440
65MAP3K100.55542149
66MAPK70.54607013
67PRKACA0.54307002
68PRKAA10.54133791
69LATS20.53953047
70TGFBR20.53938219
71CAMK2G0.52533498
72CDK30.51838409
73NEK90.49911227
74STK40.49767600
75MAPK40.48612455
76BCR0.48535355
77NLK0.48392044
78CAMK40.46948941
79MAPKAPK30.46344874
80MAP3K70.45765212
81PAK30.45252174
82WNK40.44320868
83PRKACB0.44090223
84MAPK150.43483825
85RPS6KA10.42577682
86PAK20.42113977
87MAP2K10.41144205
88SGK4940.40975745
89SGK2230.40975745
90CLK10.40687358
91MAP2K60.39620393
92SGK10.39380792
93TEC0.38999711
94IRAK20.38502734
95AKT20.37830485
96ROCK20.37462991
97CAMK10.37256862
98RPS6KC10.36289638
99RPS6KL10.36289638
100TTK0.35025918
101MOS0.34540389
102MAP2K40.34207274
103DAPK30.33564748
104PRKCQ0.33067474
105BLK0.32911364
106MARK10.32461457
107MAP2K30.32455317
108RPS6KA60.32280127
109PBK0.32235272
110NTRK20.31804472
111TSSK60.30841210
112VRK20.30400426
113CAMK2B0.30220512
114ADRBK10.30146625
115BRD40.29316450
116LIMK10.29157661
117RPS6KB20.29021005
118EPHB10.28064363
119MAP3K50.26924999
120PRKACG0.26506774
121RPS6KA30.26199148
122STK380.25912425
123IKBKE0.25374368
124LATS10.24477624
125DYRK1B0.24437894
126EPHB20.24283209
127TRIB30.22198684
128MAPK100.20691140
129CDK190.20580270
130CCNB10.19778686
131SGK30.19039602
132MTOR0.17631236
133UHMK10.15506438
134MAPK90.13827553
135PRKG20.13635741
136MARK30.13608613
137PRKDC0.12179563
138CDC70.11149400
139KSR20.10180624
140AKT10.08381432
141FGFR40.06986907
142BUB10.05629547
143GSK3B0.04818551

Predicted pathways (KEGG)

RankGene SetZ-score
1Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054104.71748233
2Cardiac muscle contraction_Homo sapiens_hsa042604.60827668
3Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004004.58463892
4Dilated cardiomyopathy_Homo sapiens_hsa054144.37212944
5Oxidative phosphorylation_Homo sapiens_hsa001903.79473026
6Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054123.54456018
7Parkinsons disease_Homo sapiens_hsa050123.32241814
8Alzheimers disease_Homo sapiens_hsa050102.86889962
9Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.58369878
10Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.42057761
11Huntingtons disease_Homo sapiens_hsa050162.35158355
12Pyruvate metabolism_Homo sapiens_hsa006201.97148009
13Viral myocarditis_Homo sapiens_hsa054161.90849583
14Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.72467675
15Taste transduction_Homo sapiens_hsa047421.58370827
16Arginine biosynthesis_Homo sapiens_hsa002201.58024285
17Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.57832419
18Calcium signaling pathway_Homo sapiens_hsa040201.53381358
19Biosynthesis of amino acids_Homo sapiens_hsa012301.52050209
20Propanoate metabolism_Homo sapiens_hsa006401.44622154
21Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.42490160
22Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.37242327
23Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.36298303
24Starch and sucrose metabolism_Homo sapiens_hsa005001.35257234
25Circadian rhythm_Homo sapiens_hsa047101.30727350
26Pentose phosphate pathway_Homo sapiens_hsa000301.14943073
27cGMP-PKG signaling pathway_Homo sapiens_hsa040221.12733498
28Oxytocin signaling pathway_Homo sapiens_hsa049211.12129183
29Fatty acid elongation_Homo sapiens_hsa000621.08023606
30Nicotine addiction_Homo sapiens_hsa050331.07514573
31Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.04477210
32Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.04004692
33Autoimmune thyroid disease_Homo sapiens_hsa053201.01308112
34Phototransduction_Homo sapiens_hsa047440.96981161
35Graft-versus-host disease_Homo sapiens_hsa053320.93223874
36Arachidonic acid metabolism_Homo sapiens_hsa005900.92501794
37Serotonergic synapse_Homo sapiens_hsa047260.90908622
382-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.88453092
39Morphine addiction_Homo sapiens_hsa050320.87505287
40Olfactory transduction_Homo sapiens_hsa047400.86371442
41AMPK signaling pathway_Homo sapiens_hsa041520.86065184
42Vascular smooth muscle contraction_Homo sapiens_hsa042700.86054380
43Cysteine and methionine metabolism_Homo sapiens_hsa002700.85122443
44Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.79659679
45PPAR signaling pathway_Homo sapiens_hsa033200.79339161
46Renin secretion_Homo sapiens_hsa049240.79241303
47Allograft rejection_Homo sapiens_hsa053300.77989417
48Insulin secretion_Homo sapiens_hsa049110.77643448
49Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.76945531
50Circadian entrainment_Homo sapiens_hsa047130.76805733
51Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.76663767
52Fatty acid degradation_Homo sapiens_hsa000710.76433133
53Rheumatoid arthritis_Homo sapiens_hsa053230.76376807
54Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.75199275
55Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.74821575
56Fructose and mannose metabolism_Homo sapiens_hsa000510.73859014
57Ovarian steroidogenesis_Homo sapiens_hsa049130.71976568
58Glucagon signaling pathway_Homo sapiens_hsa049220.69883755
59Arginine and proline metabolism_Homo sapiens_hsa003300.69654386
60cAMP signaling pathway_Homo sapiens_hsa040240.68667430
61Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.67278288
62Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.65388964
63beta-Alanine metabolism_Homo sapiens_hsa004100.65001383
64Type II diabetes mellitus_Homo sapiens_hsa049300.64424189
65Fanconi anemia pathway_Homo sapiens_hsa034600.63998183
66* Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.62431176
67NF-kappa B signaling pathway_Homo sapiens_hsa040640.57882521
68Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.56444907
69Tryptophan metabolism_Homo sapiens_hsa003800.56400548
70Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.56185542
71Linoleic acid metabolism_Homo sapiens_hsa005910.56061507
72Longevity regulating pathway - mammal_Homo sapiens_hsa042110.55952247
73Intestinal immune network for IgA production_Homo sapiens_hsa046720.55287384
74Adherens junction_Homo sapiens_hsa045200.55040241
75SNARE interactions in vesicular transport_Homo sapiens_hsa041300.53985455
76Hematopoietic cell lineage_Homo sapiens_hsa046400.53692096
77Insulin signaling pathway_Homo sapiens_hsa049100.51917438
78alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.50953952
79Regulation of autophagy_Homo sapiens_hsa041400.50869940
80Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.49685758
81Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.49624507
82Tyrosine metabolism_Homo sapiens_hsa003500.48279140
83Insulin resistance_Homo sapiens_hsa049310.47946016
84Ether lipid metabolism_Homo sapiens_hsa005650.46582390
85Purine metabolism_Homo sapiens_hsa002300.45587439
86Tight junction_Homo sapiens_hsa045300.45063473
87Glutamatergic synapse_Homo sapiens_hsa047240.43676336
88Proteasome_Homo sapiens_hsa030500.43652997
89Axon guidance_Homo sapiens_hsa043600.43231419
90ECM-receptor interaction_Homo sapiens_hsa045120.42586110
91Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.42337817
92Collecting duct acid secretion_Homo sapiens_hsa049660.40851255
93Carbon metabolism_Homo sapiens_hsa012000.40350062
94Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.40180984
95Adipocytokine signaling pathway_Homo sapiens_hsa049200.39243498
96Cholinergic synapse_Homo sapiens_hsa047250.38962923
97Asthma_Homo sapiens_hsa053100.38884479
98GABAergic synapse_Homo sapiens_hsa047270.38777969
99MAPK signaling pathway_Homo sapiens_hsa040100.38672310
100Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.38280289
101Fatty acid metabolism_Homo sapiens_hsa012120.38254659
102Thyroid hormone signaling pathway_Homo sapiens_hsa049190.38012522
103Galactose metabolism_Homo sapiens_hsa000520.37768538
104Butanoate metabolism_Homo sapiens_hsa006500.36988491
105Regulation of actin cytoskeleton_Homo sapiens_hsa048100.36948947
106RNA polymerase_Homo sapiens_hsa030200.36420264
107Focal adhesion_Homo sapiens_hsa045100.34803052
108Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.34309999
109HIF-1 signaling pathway_Homo sapiens_hsa040660.34209555
110Sulfur relay system_Homo sapiens_hsa041220.33890580
111Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.32825022
112Sphingolipid metabolism_Homo sapiens_hsa006000.32518976
113Oocyte meiosis_Homo sapiens_hsa041140.30497789
114Measles_Homo sapiens_hsa051620.30204302
115Toll-like receptor signaling pathway_Homo sapiens_hsa046200.29940146
116FoxO signaling pathway_Homo sapiens_hsa040680.29923269
117Jak-STAT signaling pathway_Homo sapiens_hsa046300.29792578
118Salmonella infection_Homo sapiens_hsa051320.29167939
119* Metabolic pathways_Homo sapiens_hsa011000.28466803
120Phenylalanine metabolism_Homo sapiens_hsa003600.28006858
121Folate biosynthesis_Homo sapiens_hsa007900.24974165
122NOD-like receptor signaling pathway_Homo sapiens_hsa046210.22371136
123Gastric acid secretion_Homo sapiens_hsa049710.22057804
124Lysine degradation_Homo sapiens_hsa003100.21979403
125Central carbon metabolism in cancer_Homo sapiens_hsa052300.21638416
126Type I diabetes mellitus_Homo sapiens_hsa049400.21467209
127GnRH signaling pathway_Homo sapiens_hsa049120.21262533
128Glutathione metabolism_Homo sapiens_hsa004800.21157125
129Pancreatic secretion_Homo sapiens_hsa049720.20068595
130Melanogenesis_Homo sapiens_hsa049160.18155295
131Gap junction_Homo sapiens_hsa045400.17236782
132Peroxisome_Homo sapiens_hsa041460.16873112
133Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.16173929
134Long-term potentiation_Homo sapiens_hsa047200.14441847
135Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.13059320
136Aldosterone synthesis and secretion_Homo sapiens_hsa049250.11648485
137RNA degradation_Homo sapiens_hsa030180.11281547
138Bile secretion_Homo sapiens_hsa049760.08413903
139Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.07324400
140Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.06390775
141Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.06122268
142Ribosome_Homo sapiens_hsa030100.05011426
143Glycerophospholipid metabolism_Homo sapiens_hsa005640.04235072
144Salivary secretion_Homo sapiens_hsa049700.03521130

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