NOC3L

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore organization (GO:0006999)6.00221622
2nuclear pore complex assembly (GO:0051292)5.98414191
3pore complex assembly (GO:0046931)4.68324151
4DNA strand elongation (GO:0022616)4.42766249
5protein localization to kinetochore (GO:0034501)4.39980969
6telomere maintenance via semi-conservative replication (GO:0032201)4.31877114
7ribosome assembly (GO:0042255)4.16622089
8DNA unwinding involved in DNA replication (GO:0006268)4.14877222
9mitotic nuclear envelope disassembly (GO:0007077)4.00307729
10telomere maintenance via recombination (GO:0000722)3.99089685
11mitotic sister chromatid cohesion (GO:0007064)3.96886557
12mitotic recombination (GO:0006312)3.92153914
13DNA replication-dependent nucleosome organization (GO:0034723)3.91396822
14DNA replication-dependent nucleosome assembly (GO:0006335)3.91396822
15maturation of SSU-rRNA (GO:0030490)3.87643361
16mitotic metaphase plate congression (GO:0007080)3.85068760
17regulation of helicase activity (GO:0051095)3.82837461
18double-strand break repair via nonhomologous end joining (GO:0006303)3.82705034
19non-recombinational repair (GO:0000726)3.82705034
20regulation of histone H3-K9 methylation (GO:0051570)3.80749428
21DNA replication initiation (GO:0006270)3.76620456
22IMP biosynthetic process (GO:0006188)3.72419576
23membrane disassembly (GO:0030397)3.72334592
24nuclear envelope disassembly (GO:0051081)3.72334592
25regulation of RNA export from nucleus (GO:0046831)3.71827242
26regulation of mitotic metaphase/anaphase transition (GO:0030071)3.66081269
27regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.66081269
28establishment of protein localization to mitochondrial membrane (GO:0090151)3.57301026
29mitotic sister chromatid segregation (GO:0000070)3.55363994
30mitotic spindle checkpoint (GO:0071174)3.53808437
31DNA ligation (GO:0006266)3.53336727
32protein localization to chromosome, centromeric region (GO:0071459)3.51796962
33negative regulation of chromosome segregation (GO:0051985)3.51664018
34ribosome biogenesis (GO:0042254)3.51470211
35positive regulation of chromosome segregation (GO:0051984)3.51238253
36negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.50625966
37negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.50625966
38negative regulation of mitotic sister chromatid segregation (GO:0033048)3.50625966
39negative regulation of mitotic sister chromatid separation (GO:2000816)3.50625966
40negative regulation of sister chromatid segregation (GO:0033046)3.50625966
41regulation of mitotic sister chromatid separation (GO:0010965)3.49898358
42regulation of mitotic sister chromatid segregation (GO:0033047)3.49898358
43regulation of sister chromatid segregation (GO:0033045)3.49898358
44folic acid-containing compound biosynthetic process (GO:0009396)3.46653415
45regulation of gene silencing by RNA (GO:0060966)3.45081144
46regulation of posttranscriptional gene silencing (GO:0060147)3.45081144
47regulation of gene silencing by miRNA (GO:0060964)3.45081144
48regulation of mitotic spindle organization (GO:0060236)3.44038511
49regulation of spindle organization (GO:0090224)3.43416078
50regulation of mitotic spindle checkpoint (GO:1903504)3.43256800
51regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.43256800
52DNA double-strand break processing (GO:0000729)3.42941294
53anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.41214166
54IMP metabolic process (GO:0046040)3.41130394
55nucleotide-excision repair, DNA gap filling (GO:0006297)3.40923041
56metaphase plate congression (GO:0051310)3.38821048
57chromatin remodeling at centromere (GO:0031055)3.38575459
58sister chromatid segregation (GO:0000819)3.37270754
59heterochromatin organization (GO:0070828)3.33940135
60proteasome assembly (GO:0043248)3.33749320
61mitotic spindle assembly checkpoint (GO:0007094)3.32441047
62spindle assembly checkpoint (GO:0071173)3.31898088
63histone H2A monoubiquitination (GO:0035518)3.31783412
64nucleobase biosynthetic process (GO:0046112)3.31513142
65DNA geometric change (GO:0032392)3.30392369
66DNA duplex unwinding (GO:0032508)3.30389873
67negative regulation of histone methylation (GO:0031061)3.30000508
68establishment of viral latency (GO:0019043)3.29439222
69regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.28723711
70positive regulation of histone H3-K4 methylation (GO:0051571)3.28051051
71postreplication repair (GO:0006301)3.27145229
72telomere maintenance via telomere lengthening (GO:0010833)3.26937871
73chromatin assembly (GO:0031497)3.26418136
74ribonucleoprotein complex biogenesis (GO:0022613)3.25709359
75negative regulation of DNA-dependent DNA replication (GO:2000104)3.24716767
76regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.21829512
77rRNA processing (GO:0006364)3.21507207
78CENP-A containing nucleosome assembly (GO:0034080)3.20017931
79chromosome segregation (GO:0007059)3.19696375
80kinetochore organization (GO:0051383)3.17424593
81establishment of integrated proviral latency (GO:0075713)3.17351370
82mitotic G2/M transition checkpoint (GO:0044818)3.16975032
83regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.16888600
84response to X-ray (GO:0010165)3.16809599
85negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.16598484
86positive regulation of mitotic sister chromatid separation (GO:1901970)3.16342168
87positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.16342168
88positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.16342168
89ribosomal large subunit biogenesis (GO:0042273)3.14430838
90DNA replication checkpoint (GO:0000076)3.14336674
91rRNA metabolic process (GO:0016072)3.12938498
92pre-miRNA processing (GO:0031054)3.11434539
93formation of translation preinitiation complex (GO:0001731)3.10981461
94regulation of centrosome cycle (GO:0046605)3.10431829
95negative regulation of DNA repair (GO:0045738)3.09405918
96mitotic chromosome condensation (GO:0007076)3.08471366
97somatic recombination of immunoglobulin gene segments (GO:0016447)3.04290215
98maturation of 5.8S rRNA (GO:0000460)3.04054897
99somatic hypermutation of immunoglobulin genes (GO:0016446)3.03744542
100somatic diversification of immune receptors via somatic mutation (GO:0002566)3.03744542
101cell cycle G1/S phase transition (GO:0044843)3.02970430
102G1/S transition of mitotic cell cycle (GO:0000082)3.02970430
103DNA catabolic process, exonucleolytic (GO:0000738)3.02176236
104protein K6-linked ubiquitination (GO:0085020)3.01548665
105rRNA modification (GO:0000154)3.01323875
106DNA replication-independent nucleosome assembly (GO:0006336)2.99659840
107DNA replication-independent nucleosome organization (GO:0034724)2.99659840
108attachment of spindle microtubules to kinetochore (GO:0008608)2.97348574
109isotype switching (GO:0045190)2.95577785
110somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.95577785
111somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.95577785
112histone exchange (GO:0043486)2.94025565
113regulation of DNA endoreduplication (GO:0032875)2.92117201
114regulation of nucleobase-containing compound transport (GO:0032239)2.91401315
115establishment of chromosome localization (GO:0051303)2.88151311
116microtubule depolymerization (GO:0007019)2.87577670
117determination of adult lifespan (GO:0008340)2.87460612
118chaperone-mediated protein complex assembly (GO:0051131)2.86965539
119regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.86871820
120purine nucleobase biosynthetic process (GO:0009113)2.86260139
121meiotic chromosome segregation (GO:0045132)2.85760779
122chromatin assembly or disassembly (GO:0006333)2.83955771
123regulation of meiosis I (GO:0060631)2.83283853
124nuclear envelope organization (GO:0006998)2.82712092
125regulation of nuclear cell cycle DNA replication (GO:0033262)2.81463195
126regulation of sister chromatid cohesion (GO:0007063)2.81383089
127DNA strand elongation involved in DNA replication (GO:0006271)2.81237796
128ribosomal small subunit biogenesis (GO:0042274)2.80687429
129mRNA transport (GO:0051028)2.78566138
130regulation of centriole replication (GO:0046599)2.75727549
131spindle checkpoint (GO:0031577)2.75132433
132regulation of chromosome segregation (GO:0051983)2.74523124
133kinetochore assembly (GO:0051382)2.74218200
134spindle assembly involved in mitosis (GO:0090307)2.73098802
135negative regulation of histone modification (GO:0031057)2.71198295
136regulation of centrosome duplication (GO:0010824)2.71025153
137regulation of telomere maintenance via telomerase (GO:0032210)2.69989646
138spliceosomal complex assembly (GO:0000245)2.69987557
139negative regulation of chromatin modification (GO:1903309)2.68991040
140regulation of translational termination (GO:0006449)2.67804555
141regulation of translation in response to stress (GO:0043555)2.67649767
142sister chromatid cohesion (GO:0007062)2.67580789

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.89484029
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.45645380
3* E2F4_17652178_ChIP-ChIP_JURKAT_Human4.34559515
4* MYC_18555785_ChIP-Seq_MESCs_Mouse4.15379631
5SALL1_21062744_ChIP-ChIP_HESCs_Human3.32150114
6* KDM5B_21448134_ChIP-Seq_MESCs_Mouse3.14225072
7* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.11342276
8* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.07837446
9FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.93317251
10* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.73014921
11KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.50835152
12KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.50835152
13KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.50835152
14EST1_17652178_ChIP-ChIP_JURKAT_Human2.49030780
15RBPJ_22232070_ChIP-Seq_NCS_Mouse2.41909725
16EGR1_19374776_ChIP-ChIP_THP-1_Human2.36659839
17CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.31883229
18NELFA_20434984_ChIP-Seq_ESCs_Mouse2.25552997
19KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.21239697
20MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.18670171
21MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.17952590
22AR_21909140_ChIP-Seq_LNCAP_Human2.17445073
23ETS1_20019798_ChIP-Seq_JURKAT_Human2.10195588
24* GABP_17652178_ChIP-ChIP_JURKAT_Human2.09824024
25E2F1_21310950_ChIP-Seq_MCF-7_Human2.09411758
26ELK1_19687146_ChIP-ChIP_HELA_Human2.01449244
27* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.00953771
28* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.96148343
29XRN2_22483619_ChIP-Seq_HELA_Human1.95313464
30* VDR_23849224_ChIP-Seq_CD4+_Human1.95035845
31* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.92853557
32SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.90354797
33YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.87066308
34POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.86439766
35CREB1_15753290_ChIP-ChIP_HEK293T_Human1.78078603
36MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.64635894
37NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.64520062
38TTF2_22483619_ChIP-Seq_HELA_Human1.64012570
39FOXP3_21729870_ChIP-Seq_TREG_Human1.62249869
40* JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.60801609
41TP63_19390658_ChIP-ChIP_HaCaT_Human1.60314028
42PADI4_21655091_ChIP-ChIP_MCF-7_Human1.58727118
43POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.54004436
44NANOG_18555785_ChIP-Seq_MESCs_Mouse1.53183443
45HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.51318472
46PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.48910081
47SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.48608288
48FUS_26573619_Chip-Seq_HEK293_Human1.48353648
49POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.45637192
50PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.42891772
51DCP1A_22483619_ChIP-Seq_HELA_Human1.42048160
52SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.40744081
53* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.38666298
54SOX2_18555785_ChIP-Seq_MESCs_Mouse1.36522607
55NOTCH1_21737748_ChIP-Seq_TLL_Human1.36442430
56NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.35751843
57* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.34488872
58* EWS_26573619_Chip-Seq_HEK293_Human1.33665099
59ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.31046875
60SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.30982345
61TCF3_18692474_ChIP-Seq_MEFs_Mouse1.30063918
62TCF3_18692474_ChIP-Seq_MESCs_Mouse1.29929739
63SRF_21415370_ChIP-Seq_HL-1_Mouse1.28897806
64SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.26597558
65THAP11_20581084_ChIP-Seq_MESCs_Mouse1.25912761
66* KDM5A_27292631_Chip-Seq_BREAST_Human1.24447291
67NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.24222832
68POU5F1_16153702_ChIP-ChIP_HESCs_Human1.23048488
69* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.22028532
70MYC_18940864_ChIP-ChIP_HL60_Human1.17680629
71E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.14525633
72STAT3_1855785_ChIP-Seq_MESCs_Mouse1.09385462
73ERG_20887958_ChIP-Seq_HPC-7_Mouse1.09296792
74BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.09154673
75HOXB4_20404135_ChIP-ChIP_EML_Mouse1.07912257
76CIITA_25753668_ChIP-Seq_RAJI_Human1.05821847
77ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.05591419
78* GABP_19822575_ChIP-Seq_HepG2_Human1.05568489
79ZFX_18555785_ChIP-Seq_MESCs_Mouse1.04625205
80KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.04238423
81ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.03564751
82SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.03486800
83SOX2_16153702_ChIP-ChIP_HESCs_Human1.03352054
84NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.02113722
85SOX17_20123909_ChIP-Seq_XEN_Mouse1.00440333
86* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.00381758
87YY1_21170310_ChIP-Seq_MESCs_Mouse1.00223251
88CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.99334047
89CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.98485081
90IRF1_19129219_ChIP-ChIP_H3396_Human0.97951385
91KLF4_18555785_ChIP-Seq_MESCs_Mouse0.97483900
92FLI1_27457419_Chip-Seq_LIVER_Mouse0.96908455
93HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.96803232
94TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.95532393
95ESR1_15608294_ChIP-ChIP_MCF-7_Human0.94390752
96DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.92988637
97TFEB_21752829_ChIP-Seq_HELA_Human0.92894793
98NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.92387208
99HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.92154371
100ELF1_17652178_ChIP-ChIP_JURKAT_Human0.91818651
101ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.90970110
102PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.90677721
103HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.88102592
104POU3F2_20337985_ChIP-ChIP_501MEL_Human0.87091566
105MYC_22102868_ChIP-Seq_BL_Human0.86088656
106CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.83992728
107PKCTHETA_26484144_Chip-Seq_BREAST_Human0.83423605
108CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.82920638
109NANOG_21062744_ChIP-ChIP_HESCs_Human0.82366557
110* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.82093802
111POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.81868287
112DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.80942015
113NANOG_16153702_ChIP-ChIP_HESCs_Human0.79371263
114ELK1_22589737_ChIP-Seq_MCF10A_Human0.78784172
115CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.74411040
116RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.73046858
117* ELF5_23300383_ChIP-Seq_T47D_Human0.72420309
118TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.72344965
119SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.71396914
120* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.70742868
121CHD1_26751641_Chip-Seq_LNCaP_Human0.70278662
122CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.69876610
123GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.66674119

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication5.80909033
2MP0010094_abnormal_chromosome_stability4.14998795
3MP0003693_abnormal_embryo_hatching3.96697680
4MP0003111_abnormal_nucleus_morphology3.77051925
5MP0004957_abnormal_blastocyst_morpholog3.75094375
6MP0003077_abnormal_cell_cycle3.53383569
7MP0008058_abnormal_DNA_repair3.15340730
8MP0009697_abnormal_copulation3.08767821
9MP0003123_paternal_imprinting2.76822693
10MP0008877_abnormal_DNA_methylation2.44191511
11MP0008932_abnormal_embryonic_tissue2.37293687
12MP0000350_abnormal_cell_proliferation2.33925421
13MP0010352_gastrointestinal_tract_polyps2.24381715
14MP0003890_abnormal_embryonic-extraembry2.22000146
15MP0001730_embryonic_growth_arrest2.12910243
16MP0003136_yellow_coat_color2.12822576
17MP0008007_abnormal_cellular_replicative2.09966474
18MP0003786_premature_aging2.06097597
19MP0003121_genomic_imprinting2.01029699
20MP0002084_abnormal_developmental_patter1.88631728
21MP0010307_abnormal_tumor_latency1.88418044
22MP0005380_embryogenesis_phenotype1.83746950
23MP0001672_abnormal_embryogenesis/_devel1.83746950
24MP0002085_abnormal_embryonic_tissue1.77968201
25MP0003937_abnormal_limbs/digits/tail_de1.75754213
26MP0003941_abnormal_skin_development1.72884326
27MP0001697_abnormal_embryo_size1.70520698
28MP0002396_abnormal_hematopoietic_system1.67041246
29MP0006292_abnormal_olfactory_placode1.66104938
30MP0004197_abnormal_fetal_growth/weight/1.59003947
31MP0003984_embryonic_growth_retardation1.56249036
32MP0002088_abnormal_embryonic_growth/wei1.52781105
33MP0002086_abnormal_extraembryonic_tissu1.51133560
34MP0002080_prenatal_lethality1.40261160
35MP0001293_anophthalmia1.39306011
36MP0003806_abnormal_nucleotide_metabolis1.37427924
37MP0002210_abnormal_sex_determination1.32369187
38MP0005395_other_phenotype1.25321410
39MP0002234_abnormal_pharynx_morphology1.24589849
40MP0003755_abnormal_palate_morphology1.20268696
41MP0005076_abnormal_cell_differentiation1.18153096
42MP0001145_abnormal_male_reproductive1.16979103
43MP0000432_abnormal_head_morphology1.11027035
44MP0003718_maternal_effect1.09008853
45MP0002111_abnormal_tail_morphology1.08800819
46MP0000358_abnormal_cell_content/1.08309085
47MP0002877_abnormal_melanocyte_morpholog1.06377491
48MP0003567_abnormal_fetal_cardiomyocyte1.06225909
49MP0004133_heterotaxia1.05910491
50MP0000313_abnormal_cell_death1.05572718
51MP0003119_abnormal_digestive_system1.04909998
52MP0006035_abnormal_mitochondrial_morpho1.03208536
53MP0003787_abnormal_imprinting1.01110817
54MP0001188_hyperpigmentation1.00437284
55MP0001929_abnormal_gametogenesis1.00290667
56MP0001286_abnormal_eye_development0.99877525
57MP0003221_abnormal_cardiomyocyte_apopto0.99829224
58MP0004808_abnormal_hematopoietic_stem0.99346838
59MP0000653_abnormal_sex_gland0.98547456
60MP0003938_abnormal_ear_development0.98014466
61MP0009703_decreased_birth_body0.96769609
62MP0003861_abnormal_nervous_system0.96483875
63MP0003186_abnormal_redox_activity0.96397934
64MP0000428_abnormal_craniofacial_morphol0.93241192
65MP0000537_abnormal_urethra_morphology0.91688045
66MP0009672_abnormal_birth_weight0.91521539
67MP0002092_abnormal_eye_morphology0.90235526
68MP0009053_abnormal_anal_canal0.89384450
69MP0003935_abnormal_craniofacial_develop0.88813670
70MP0002006_tumorigenesis0.88354371
71MP0002114_abnormal_axial_skeleton0.87673519
72MP0002019_abnormal_tumor_incidence0.87457910
73MP0002938_white_spotting0.87341661
74MP0003950_abnormal_plasma_membrane0.86950719
75MP0005623_abnormal_meninges_morphology0.86915230
76MP0000733_abnormal_muscle_development0.86878370
77MP0006036_abnormal_mitochondrial_physio0.85228198
78MP0002233_abnormal_nose_morphology0.84702950
79MP0002009_preneoplasia0.84665827
80MP0000490_abnormal_crypts_of0.83873956
81MP0005621_abnormal_cell_physiology0.83390531
82MP0003699_abnormal_female_reproductive0.83257351
83MP0010678_abnormal_skin_adnexa0.82785010
84MP0002697_abnormal_eye_size0.82707718
85MP0003566_abnormal_cell_adhesion0.82135577
86MP0005408_hypopigmentation0.82130637
87MP0000703_abnormal_thymus_morphology0.79767754
88MP0002796_impaired_skin_barrier0.77133691
89MP0005501_abnormal_skin_physiology0.77034922
90MP0000372_irregular_coat_pigmentation0.75450874
91MP0004233_abnormal_muscle_weight0.75075318
92MP0001119_abnormal_female_reproductive0.75033895
93MP0005384_cellular_phenotype0.72530994
94MP0003936_abnormal_reproductive_system0.72140361
95MP0010030_abnormal_orbit_morphology0.71220519
96MP0000383_abnormal_hair_follicle0.70279062
97MP0002160_abnormal_reproductive_system0.69446654
98MP0008770_decreased_survivor_rate0.67976101
99MP0002102_abnormal_ear_morphology0.67718102
100MP0004134_abnormal_chest_morphology0.67264554
101MP0005389_reproductive_system_phenotype0.67131509
102MP0000762_abnormal_tongue_morphology0.66977588
103MP0002060_abnormal_skin_morphology0.65970862
104MP0000627_abnormal_mammary_gland0.65520500
105MP0001853_heart_inflammation0.65291946
106MP0002163_abnormal_gland_morphology0.64954929
107MP0003385_abnormal_body_wall0.64479927
108MP0002925_abnormal_cardiovascular_devel0.64421129
109MP0009379_abnormal_foot_pigmentation0.64075751
110MP0003828_pulmonary_edema0.63791748
111MP0001727_abnormal_embryo_implantation0.63548170
112MP0010234_abnormal_vibrissa_follicle0.63031165
113MP0002116_abnormal_craniofacial_bone0.62413601
114MP0004185_abnormal_adipocyte_glucose0.62042382
115MP0008789_abnormal_olfactory_epithelium0.61880523
116MP0003698_abnormal_male_reproductive0.61597161
117MP0001346_abnormal_lacrimal_gland0.61563262
118MP0003943_abnormal_hepatobiliary_system0.61236129
119MP0002751_abnormal_autonomic_nervous0.60875089
120MP0002653_abnormal_ependyma_morphology0.60773821
121MP0001661_extended_life_span0.60024606
122MP0005394_taste/olfaction_phenotype0.60000824
123MP0005499_abnormal_olfactory_system0.60000824
124MP0000647_abnormal_sebaceous_gland0.58612247
125MP0002081_perinatal_lethality0.58006243
126MP0002161_abnormal_fertility/fecundity0.57937856
127MP0006072_abnormal_retinal_apoptosis0.57933579
128MP0001881_abnormal_mammary_gland0.57709794
129MP0002269_muscular_atrophy0.57227134
130MP0000427_abnormal_hair_cycle0.54738325

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the labia minora (HP:0012880)4.59176128
2Chromsome breakage (HP:0040012)4.25264956
3Chromosomal breakage induced by crosslinking agents (HP:0003221)4.01132393
4Birth length less than 3rd percentile (HP:0003561)3.88501793
5Volvulus (HP:0002580)3.11042138
6Facial hemangioma (HP:0000329)3.05046699
7Ependymoma (HP:0002888)2.99633634
8Abnormality of chromosome stability (HP:0003220)2.99085394
9Medulloblastoma (HP:0002885)2.89656072
10Impulsivity (HP:0100710)2.82395226
11Microvesicular hepatic steatosis (HP:0001414)2.74534790
12Meckel diverticulum (HP:0002245)2.72994863
13Absent radius (HP:0003974)2.71770430
14Abnormality of the preputium (HP:0100587)2.70218178
15Aplasia/Hypoplasia of the uvula (HP:0010293)2.69222403
16Abnormality of methionine metabolism (HP:0010901)2.62384194
17Abnormality of the ileum (HP:0001549)2.62235431
18Progressive external ophthalmoplegia (HP:0000590)2.60442211
19Agnosia (HP:0010524)2.58958568
20Neoplasm of the oral cavity (HP:0100649)2.54938269
21Aplasia involving forearm bones (HP:0009822)2.54265061
22Absent forearm bone (HP:0003953)2.54265061
23Supernumerary spleens (HP:0009799)2.53094139
24Increased nuchal translucency (HP:0010880)2.52270676
25Rhabdomyosarcoma (HP:0002859)2.50950524
26Breast hypoplasia (HP:0003187)2.49475697
27Sensory axonal neuropathy (HP:0003390)2.47767477
28Multiple enchondromatosis (HP:0005701)2.46405357
29Abnormality of the carotid arteries (HP:0005344)2.44047770
30Proximal placement of thumb (HP:0009623)2.43797455
31Abnormality of the astrocytes (HP:0100707)2.43165600
32Astrocytoma (HP:0009592)2.43165600
33Deviation of the thumb (HP:0009603)2.39976018
34Cerebral hypomyelination (HP:0006808)2.39870132
35Microglossia (HP:0000171)2.34491621
36Selective tooth agenesis (HP:0001592)2.33963840
37Colon cancer (HP:0003003)2.32567538
38Increased serum pyruvate (HP:0003542)2.32158318
39Myelodysplasia (HP:0002863)2.29961223
40Esophageal atresia (HP:0002032)2.29901114
41Patellar aplasia (HP:0006443)2.28570721
42Increased hepatocellular lipid droplets (HP:0006565)2.27710812
43Aplastic anemia (HP:0001915)2.25708749
44Aplasia/hypoplasia of the humerus (HP:0006507)2.23313995
45Neoplasm of the colon (HP:0100273)2.22662343
46Median cleft lip (HP:0000161)2.22042900
47Abnormality of glycolysis (HP:0004366)2.19412103
48Short humerus (HP:0005792)2.16126056
49Absent thumb (HP:0009777)2.15880461
50Aplasia/Hypoplasia of the patella (HP:0006498)2.15128446
51Ectopic kidney (HP:0000086)2.14950262
52Reticulocytopenia (HP:0001896)2.12148663
53Progressive muscle weakness (HP:0003323)2.11849981
54Abnormal number of incisors (HP:0011064)2.10301827
55Short thumb (HP:0009778)2.08452176
56Small intestinal stenosis (HP:0012848)2.08317268
57Duodenal stenosis (HP:0100867)2.08317268
58Rib fusion (HP:0000902)2.07843528
59Aplasia/Hypoplasia of the sternum (HP:0006714)2.07191247
60Nephroblastoma (Wilms tumor) (HP:0002667)2.07173857
61Stillbirth (HP:0003826)2.05763567
62Acute myeloid leukemia (HP:0004808)2.05085705
63Deep philtrum (HP:0002002)2.04731973
64Biliary tract neoplasm (HP:0100574)2.04178997
65Facial cleft (HP:0002006)2.02812183
66Glioma (HP:0009733)2.02260979
67Short middle phalanx of the 5th finger (HP:0004220)2.01215603
68Lipid accumulation in hepatocytes (HP:0006561)2.00656427
69Megaloblastic anemia (HP:0001889)2.00018824
70Abnormality of aspartate family amino acid metabolism (HP:0010899)1.98761613
71Amaurosis fugax (HP:0100576)1.96015196
72Atresia of the external auditory canal (HP:0000413)1.94692730
73Abnormality of the septum pellucidum (HP:0007375)1.93583489
74Bifid tongue (HP:0010297)1.92975374
75Neoplasm of striated muscle (HP:0009728)1.92881239
76Abnormality of the umbilical cord (HP:0010881)1.91551604
77Embryonal renal neoplasm (HP:0011794)1.91311390
78Supernumerary bones of the axial skeleton (HP:0009144)1.89117756
79Abnormal lung lobation (HP:0002101)1.88352820
80Oral leukoplakia (HP:0002745)1.87836424
81Stenosis of the external auditory canal (HP:0000402)1.86230084
82Cystic hygroma (HP:0000476)1.85639758
83Gastrointestinal atresia (HP:0002589)1.85182678
84Amniotic constriction ring (HP:0009775)1.83855842
85Abnormality of placental membranes (HP:0011409)1.83855842
86Sloping forehead (HP:0000340)1.83517373
87Sparse lateral eyebrow (HP:0005338)1.83285616
88Fused cervical vertebrae (HP:0002949)1.82994958
89Basal cell carcinoma (HP:0002671)1.82593452
90Abnormality of the antihelix (HP:0009738)1.82458181
91Abnormality of the anterior horn cell (HP:0006802)1.81243891
92Degeneration of anterior horn cells (HP:0002398)1.81243891
93Abnormalities of placenta or umbilical cord (HP:0001194)1.81243530
94Rectal fistula (HP:0100590)1.80537373
95Rectovaginal fistula (HP:0000143)1.80537373
96Neoplasm of the small intestine (HP:0100833)1.80311586
97Abnormality of the duodenum (HP:0002246)1.79850123
98Increased serum lactate (HP:0002151)1.79087361
99Cortical dysplasia (HP:0002539)1.78764753
100Abnormality of the pons (HP:0007361)1.78322987
101Microtia (HP:0008551)1.78244661
102Squamous cell carcinoma (HP:0002860)1.77523350
103Glossoptosis (HP:0000162)1.77129156
104Supernumerary ribs (HP:0005815)1.76731720
105Embryonal neoplasm (HP:0002898)1.75875810
106Papillary thyroid carcinoma (HP:0002895)1.75757493
107Horseshoe kidney (HP:0000085)1.75131315
108Duplicated collecting system (HP:0000081)1.75076299
109Short 1st metacarpal (HP:0010034)1.74680398
110Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.74680398
111Capillary hemangiomas (HP:0005306)1.74603735
112Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.72181222
113Degeneration of the lateral corticospinal tracts (HP:0002314)1.72181222
114Premature ovarian failure (HP:0008209)1.72061957
115Oligodactyly (hands) (HP:0001180)1.71980292
116Prominent nose (HP:0000448)1.71809474
117Arteriovenous malformation (HP:0100026)1.70958091
118Abnormality of DNA repair (HP:0003254)1.70671702
119Cafe-au-lait spot (HP:0000957)1.70323011
120Rough bone trabeculation (HP:0100670)1.70089447
121Macrocytic anemia (HP:0001972)1.70083112
122Asplenia (HP:0001746)1.69773812
123Ovarian neoplasm (HP:0100615)1.69736452
124Secondary amenorrhea (HP:0000869)1.69492014
125Posterior subcapsular cataract (HP:0007787)1.69423913
126Abnormality of chromosome segregation (HP:0002916)1.69272797
127Abnormal spermatogenesis (HP:0008669)1.69232308
128Triphalangeal thumb (HP:0001199)1.68587013
129Pancreatic islet-cell hyperplasia (HP:0004510)1.68449201
130Bone marrow hypocellularity (HP:0005528)1.68206650
131Cleft eyelid (HP:0000625)1.67690799
132Hypoplasia of the pons (HP:0012110)1.67001499
133Abnormal umbilical cord blood vessels (HP:0011403)1.66988049
134Single umbilical artery (HP:0001195)1.66988049
135Abnormality of the fetal cardiovascular system (HP:0010948)1.66988049
136Gastrointestinal carcinoma (HP:0002672)1.66908445
137Malignant gastrointestinal tract tumors (HP:0006749)1.66908445
138Uterine neoplasm (HP:0010784)1.66718651
139Choanal atresia (HP:0000453)1.66677559
140Aplasia/Hypoplasia of the earlobes (HP:0009906)1.66620546
141Intestinal fistula (HP:0100819)1.66316591
142Type I transferrin isoform profile (HP:0003642)1.66163635
143Large earlobe (HP:0009748)1.65098704
144Missing ribs (HP:0000921)1.65080945
145Clitoromegaly (HP:0000057)1.64959273
146Abdominal situs inversus (HP:0003363)1.64826936
147Abnormality of abdominal situs (HP:0011620)1.64826936
148Neoplasm of the pancreas (HP:0002894)1.64790545
149Urethral obstruction (HP:0000796)1.62742033
150Clubbing of toes (HP:0100760)1.61955143
151Premature graying of hair (HP:0002216)1.61219511
152Shawl scrotum (HP:0000049)1.61002483
153Irregular epiphyses (HP:0010582)1.60382524
154Short chin (HP:0000331)1.59210496
155Abnormality of the nasal septum (HP:0000419)1.56335678

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PNCK4.43192423
2CDC74.31498915
3CDK124.01264670
4WEE13.67060163
5TSSK63.15222930
6MKNK22.84799818
7NEK12.77699631
8MKNK12.62298537
9SRPK12.60506455
10TTK2.48129761
11BUB12.19190490
12MELK2.10034388
13EPHA22.08184807
14PLK32.05395332
15BRD42.01670309
16EIF2AK11.86334166
17PLK11.84378357
18BRSK21.79386664
19CHEK21.68904400
20VRK21.66833273
21TRIM281.63828153
22MST41.62301393
23CHEK11.61870839
24STK161.57267301
25TAF11.56910029
26CDK71.54890206
27TLK11.53369538
28RPS6KB21.53068142
29ATR1.49491365
30AURKB1.46609219
31NEK21.45935126
32ALK1.45032536
33PASK1.41870729
34ATM1.33885288
35STK101.32699258
36ZAK1.21522941
37DYRK31.18209561
38MAP3K81.17127879
39NME11.10955918
40PLK41.07843172
41AURKA1.07663415
42CDK21.07660403
43VRK11.06663184
44CDK41.04441432
45ERBB31.03868440
46NME21.03804541
47STK31.01507335
48CSNK1E0.99416364
49LATS20.98730921
50RAF10.96498868
51LATS10.95908932
52EEF2K0.91058695
53EIF2AK30.88893929
54AKT30.88887192
55CSNK2A20.87080646
56NEK90.86829688
57TNIK0.86407545
58CDK10.86189456
59STK40.86070296
60CSNK1D0.85201434
61BMPR1B0.84955495
62PLK20.84100701
63STK240.82900190
64PIM10.82372265
65BRAF0.80832028
66SCYL20.78632805
67RPS6KA50.75236081
68CDK80.73996962
69RPS6KA40.73796956
70MST1R0.73223513
71ACVR1B0.72484978
72BRSK10.71671008
73PRKDC0.71272057
74NUAK10.68542672
75FGR0.68513705
76MTOR0.65692783
77NEK60.64993052
78MAP3K120.62672117
79CDK60.61077077
80MAPK140.59485542
81PAK20.58536779
82CASK0.56891796
83MAP3K90.55757792
84PDK20.55693548
85CSNK2A10.53488708
86PAK10.51412364
87STK390.50980650
88MAP3K100.50954174
89CDK90.49144261
90PAK40.48614945
91YES10.47687784
92GSK3B0.47666511
93CSNK1A1L0.47386935
94EIF2AK20.47282486
95SMG10.46369526
96STK38L0.45617503
97PRKCI0.43965075
98MAPK100.43277588
99MET0.42249604
100WNK30.40872148
101ROCK20.39903430
102CAMK1G0.38829602
103FGFR10.38714746
104CLK10.36893590
105MAPKAPK50.36213780
106CSNK1G10.34869547
107GRK60.34177824
108DDR20.33815730
109DMPK0.33502689
110RPS6KB10.33200011
111PBK0.32749099
112MAPK10.32537646
113INSR0.30640837
114AKT10.29096914
115CCNB10.28266655
116CSNK1G30.28146434
117PKN10.26905560
118ARAF0.26812898
119AKT20.26394650
120CDK30.25738663
121MUSK0.25577846
122BCR0.25169611
123ERBB40.23686694
124RIPK40.21430823
125CSK0.20639569
126TGFBR10.20346245

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.76260877
2RNA transport_Homo sapiens_hsa030133.42718038
3Mismatch repair_Homo sapiens_hsa034303.31664572
4Spliceosome_Homo sapiens_hsa030403.13314635
5DNA replication_Homo sapiens_hsa030303.11204623
6RNA polymerase_Homo sapiens_hsa030203.08147368
7Cell cycle_Homo sapiens_hsa041102.63592697
8Fanconi anemia pathway_Homo sapiens_hsa034602.52202636
9Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.50999033
10Non-homologous end-joining_Homo sapiens_hsa034502.46859383
11Nucleotide excision repair_Homo sapiens_hsa034202.46097694
12One carbon pool by folate_Homo sapiens_hsa006702.42136570
13Ribosome_Homo sapiens_hsa030102.36126393
14Homologous recombination_Homo sapiens_hsa034402.33067628
15mRNA surveillance pathway_Homo sapiens_hsa030152.28106593
16RNA degradation_Homo sapiens_hsa030182.17353623
17Basal transcription factors_Homo sapiens_hsa030221.98445893
18Base excision repair_Homo sapiens_hsa034101.91140169
19Proteasome_Homo sapiens_hsa030501.71376005
20Cysteine and methionine metabolism_Homo sapiens_hsa002701.66352644
21Systemic lupus erythematosus_Homo sapiens_hsa053221.58615703
22Pyrimidine metabolism_Homo sapiens_hsa002401.58251773
23p53 signaling pathway_Homo sapiens_hsa041151.53169652
24Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.42146269
25Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.25980209
26Epstein-Barr virus infection_Homo sapiens_hsa051691.25178256
27Selenocompound metabolism_Homo sapiens_hsa004501.24812261
28MicroRNAs in cancer_Homo sapiens_hsa052061.24537529
29Viral carcinogenesis_Homo sapiens_hsa052031.24415327
30Pyruvate metabolism_Homo sapiens_hsa006201.20321031
31Oocyte meiosis_Homo sapiens_hsa041141.18748899
32Folate biosynthesis_Homo sapiens_hsa007901.13720050
33TGF-beta signaling pathway_Homo sapiens_hsa043501.10541187
34Propanoate metabolism_Homo sapiens_hsa006401.07791548
35Vitamin B6 metabolism_Homo sapiens_hsa007501.01805116
36Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.98524888
37Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.93838822
38Biosynthesis of amino acids_Homo sapiens_hsa012300.91152401
39Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.89474892
40Hippo signaling pathway_Homo sapiens_hsa043900.88316776
41Purine metabolism_Homo sapiens_hsa002300.87575899
42Parkinsons disease_Homo sapiens_hsa050120.84250600
43HTLV-I infection_Homo sapiens_hsa051660.82941034
44Wnt signaling pathway_Homo sapiens_hsa043100.82509789
45Antigen processing and presentation_Homo sapiens_hsa046120.81313844
46Transcriptional misregulation in cancer_Homo sapiens_hsa052020.80359888
47Adherens junction_Homo sapiens_hsa045200.78952629
48Herpes simplex infection_Homo sapiens_hsa051680.78674359
49Basal cell carcinoma_Homo sapiens_hsa052170.77932449
50Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.76893784
51Carbon metabolism_Homo sapiens_hsa012000.76541276
52Fatty acid elongation_Homo sapiens_hsa000620.74957655
53Oxidative phosphorylation_Homo sapiens_hsa001900.74423738
542-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.74042811
55Steroid biosynthesis_Homo sapiens_hsa001000.72867904
56Alcoholism_Homo sapiens_hsa050340.72812741
57Small cell lung cancer_Homo sapiens_hsa052220.71614278
58Prostate cancer_Homo sapiens_hsa052150.69246968
59Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.66064046
60Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.65206643
61NF-kappa B signaling pathway_Homo sapiens_hsa040640.64962876
62Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.63515830
63Colorectal cancer_Homo sapiens_hsa052100.63015042
64Thyroid cancer_Homo sapiens_hsa052160.62598070
65Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.62374319
66Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.61158371
67Glutathione metabolism_Homo sapiens_hsa004800.60317241
68NOD-like receptor signaling pathway_Homo sapiens_hsa046210.60045417
69N-Glycan biosynthesis_Homo sapiens_hsa005100.57617651
70Type I diabetes mellitus_Homo sapiens_hsa049400.55772644
71Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.54951825
72Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.54368927
73Pathways in cancer_Homo sapiens_hsa052000.53901482
74Hedgehog signaling pathway_Homo sapiens_hsa043400.53509933
75Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.52164286
76Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.51296391
77T cell receptor signaling pathway_Homo sapiens_hsa046600.50373952
78mTOR signaling pathway_Homo sapiens_hsa041500.49722453
79Lysine degradation_Homo sapiens_hsa003100.48432267
80Pentose phosphate pathway_Homo sapiens_hsa000300.47942944
81Long-term depression_Homo sapiens_hsa047300.47365214
82Renal cell carcinoma_Homo sapiens_hsa052110.46399269
83Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.44909393
84Caffeine metabolism_Homo sapiens_hsa002320.43459836
85Graft-versus-host disease_Homo sapiens_hsa053320.43308468
86Allograft rejection_Homo sapiens_hsa053300.42795157
87Hepatitis B_Homo sapiens_hsa051610.41266555
88Shigellosis_Homo sapiens_hsa051310.39712137
89Tight junction_Homo sapiens_hsa045300.39520930
90Regulation of actin cytoskeleton_Homo sapiens_hsa048100.37021405
91Protein export_Homo sapiens_hsa030600.36702370
92Metabolic pathways_Homo sapiens_hsa011000.36653128
93Long-term potentiation_Homo sapiens_hsa047200.36264930
94Autoimmune thyroid disease_Homo sapiens_hsa053200.36071065
95Pancreatic cancer_Homo sapiens_hsa052120.35834102
96Chronic myeloid leukemia_Homo sapiens_hsa052200.35424663
97Hematopoietic cell lineage_Homo sapiens_hsa046400.35377411
98Circadian rhythm_Homo sapiens_hsa047100.35106597
99ECM-receptor interaction_Homo sapiens_hsa045120.35013509
100Alzheimers disease_Homo sapiens_hsa050100.34879776
101Melanoma_Homo sapiens_hsa052180.34742002
102Apoptosis_Homo sapiens_hsa042100.33989969
103Viral myocarditis_Homo sapiens_hsa054160.32503904
104PI3K-Akt signaling pathway_Homo sapiens_hsa041510.32485533
105FoxO signaling pathway_Homo sapiens_hsa040680.32220646
106Primary immunodeficiency_Homo sapiens_hsa053400.31641727
107Sulfur metabolism_Homo sapiens_hsa009200.31503918
108Ether lipid metabolism_Homo sapiens_hsa005650.31447449
109MAPK signaling pathway_Homo sapiens_hsa040100.31272850
110Proteoglycans in cancer_Homo sapiens_hsa052050.30826472
111Measles_Homo sapiens_hsa051620.30582602
112Estrogen signaling pathway_Homo sapiens_hsa049150.29869826
113Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.27047093
114Dorso-ventral axis formation_Homo sapiens_hsa043200.26942184
115Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.25989168
116Notch signaling pathway_Homo sapiens_hsa043300.25917502
117Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.25599823
118Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.25321076
119HIF-1 signaling pathway_Homo sapiens_hsa040660.25144625
120B cell receptor signaling pathway_Homo sapiens_hsa046620.24861239
121Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.24739981
122Melanogenesis_Homo sapiens_hsa049160.24256764
123Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.23865577
124Thyroid hormone signaling pathway_Homo sapiens_hsa049190.23524674
125Drug metabolism - other enzymes_Homo sapiens_hsa009830.22620490
126Choline metabolism in cancer_Homo sapiens_hsa052310.21955388
127Bladder cancer_Homo sapiens_hsa052190.21757741
128Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.20742583
129Legionellosis_Homo sapiens_hsa051340.20734696
130Huntingtons disease_Homo sapiens_hsa050160.20719741
131Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.18649545
132Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.18231950
133Focal adhesion_Homo sapiens_hsa045100.18181477
134Central carbon metabolism in cancer_Homo sapiens_hsa052300.17874938
135Sulfur relay system_Homo sapiens_hsa041220.17391689
136Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.17287876
137Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.17262555
138Nicotine addiction_Homo sapiens_hsa050330.17052649
139Rap1 signaling pathway_Homo sapiens_hsa040150.15863425
140Pentose and glucuronate interconversions_Homo sapiens_hsa000400.13755039
141Fatty acid metabolism_Homo sapiens_hsa012120.08436940
142Arginine and proline metabolism_Homo sapiens_hsa003300.07827100

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