NOL10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore organization (GO:0006999)5.14631987
2nuclear pore complex assembly (GO:0051292)5.10910791
3mitotic metaphase plate congression (GO:0007080)4.53952091
4protein localization to kinetochore (GO:0034501)4.48354956
5mitotic nuclear envelope disassembly (GO:0007077)4.42300930
6establishment of integrated proviral latency (GO:0075713)4.17727294
7nuclear envelope disassembly (GO:0051081)4.12439881
8membrane disassembly (GO:0030397)4.12439881
9IMP biosynthetic process (GO:0006188)4.11458149
10metaphase plate congression (GO:0051310)4.03660101
11folic acid-containing compound biosynthetic process (GO:0009396)3.98342319
12DNA replication initiation (GO:0006270)3.98055794
13pore complex assembly (GO:0046931)3.98029181
14DNA unwinding involved in DNA replication (GO:0006268)3.94492951
15proteasome assembly (GO:0043248)3.91883862
16mitotic sister chromatid segregation (GO:0000070)3.88681234
17nucleobase biosynthetic process (GO:0046112)3.81728850
18rRNA modification (GO:0000154)3.78418237
19ribosome biogenesis (GO:0042254)3.77838682
20DNA replication checkpoint (GO:0000076)3.76238900
21ribosome assembly (GO:0042255)3.72855393
22negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.70574434
23formation of translation preinitiation complex (GO:0001731)3.69743364
24double-strand break repair via nonhomologous end joining (GO:0006303)3.68127565
25non-recombinational repair (GO:0000726)3.68127565
26DNA replication-dependent nucleosome assembly (GO:0006335)3.67572232
27DNA replication-dependent nucleosome organization (GO:0034723)3.67572232
28protein localization to chromosome, centromeric region (GO:0071459)3.67275212
29establishment of chromosome localization (GO:0051303)3.64814940
30kinetochore organization (GO:0051383)3.63507470
31regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.61536645
32sister chromatid segregation (GO:0000819)3.60837583
33anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.59445141
34DNA strand elongation involved in DNA replication (GO:0006271)3.57610146
35IMP metabolic process (GO:0046040)3.54578712
36tRNA aminoacylation for protein translation (GO:0006418)3.52486288
37amino acid activation (GO:0043038)3.50273246
38tRNA aminoacylation (GO:0043039)3.50273246
39rRNA methylation (GO:0031167)3.49918298
40regulation of spindle organization (GO:0090224)3.49080731
41purine nucleobase biosynthetic process (GO:0009113)3.45002736
42positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.43808936
43DNA strand elongation (GO:0022616)3.40862652
44mitotic chromosome condensation (GO:0007076)3.40086426
45regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.37070296
46DNA geometric change (GO:0032392)3.36526331
47DNA duplex unwinding (GO:0032508)3.36031336
48negative regulation of ligase activity (GO:0051352)3.35911302
49negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.35911302
50attachment of spindle microtubules to kinetochore (GO:0008608)3.35786757
51regulation of posttranscriptional gene silencing (GO:0060147)3.32757595
52regulation of gene silencing by miRNA (GO:0060964)3.32757595
53regulation of gene silencing by RNA (GO:0060966)3.32757595
54positive regulation of chromosome segregation (GO:0051984)3.31998225
55DNA damage response, detection of DNA damage (GO:0042769)3.30769389
56meiotic chromosome segregation (GO:0045132)3.29298923
57DNA double-strand break processing (GO:0000729)3.29179425
58regulation of mitotic spindle checkpoint (GO:1903504)3.28837434
59regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.28837434
60kinetochore assembly (GO:0051382)3.28754336
61pre-miRNA processing (GO:0031054)3.28196420
62regulation of mitotic spindle organization (GO:0060236)3.26729214
63DNA catabolic process, exonucleolytic (GO:0000738)3.25677826
64spliceosomal snRNP assembly (GO:0000387)3.25373943
65regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.25140436
66chromatin remodeling at centromere (GO:0031055)3.25135192
67telomere maintenance via semi-conservative replication (GO:0032201)3.24013618
68heterochromatin organization (GO:0070828)3.23512838
69mitotic sister chromatid cohesion (GO:0007064)3.23193047
70somatic diversification of immune receptors via somatic mutation (GO:0002566)3.23166734
71somatic hypermutation of immunoglobulin genes (GO:0016446)3.23166734
72mitochondrial RNA metabolic process (GO:0000959)3.22391227
73protein K6-linked ubiquitination (GO:0085020)3.20887400
74ribosomal large subunit biogenesis (GO:0042273)3.19264408
75regulation of translational termination (GO:0006449)3.18469599
76establishment of viral latency (GO:0019043)3.16965404
77CENP-A containing nucleosome assembly (GO:0034080)3.15280279
78nuclear envelope organization (GO:0006998)3.14985309
79negative regulation of histone methylation (GO:0031061)3.11828902
80regulation of translational fidelity (GO:0006450)3.11466983
81cullin deneddylation (GO:0010388)3.10750784
82regulation of centrosome cycle (GO:0046605)3.09997706
83rRNA metabolic process (GO:0016072)3.09168156
84regulation of mitochondrial translation (GO:0070129)3.08876410
85negative regulation of chromosome segregation (GO:0051985)3.08772867
86DNA replication-independent nucleosome assembly (GO:0006336)3.08017418
87DNA replication-independent nucleosome organization (GO:0034724)3.08017418
88histone H2A monoubiquitination (GO:0035518)3.07542434
89maturation of SSU-rRNA (GO:0030490)3.07465326
90spindle checkpoint (GO:0031577)3.07353489
91regulation of helicase activity (GO:0051095)3.06846690
92transcription elongation from RNA polymerase III promoter (GO:0006385)3.05884650
93termination of RNA polymerase III transcription (GO:0006386)3.05884650
94telomere maintenance via recombination (GO:0000722)3.04399877
95regulation of chromosome segregation (GO:0051983)3.04299083
96regulation of histone H3-K9 methylation (GO:0051570)3.04110675
97positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.03857501
98positive regulation of mitotic sister chromatid separation (GO:1901970)3.03857501
99positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.03857501
100transcription from mitochondrial promoter (GO:0006390)3.03116943
101mitotic recombination (GO:0006312)3.03003349
102positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.02442960
103maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.02044691
104negative regulation of mitotic sister chromatid separation (GO:2000816)3.01191248
105negative regulation of mitotic sister chromatid segregation (GO:0033048)3.01191248
106negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.01191248
107negative regulation of sister chromatid segregation (GO:0033046)3.01191248
108spindle assembly checkpoint (GO:0071173)3.00900097
109regulation of mitotic metaphase/anaphase transition (GO:0030071)3.00600618
110cell cycle G1/S phase transition (GO:0044843)2.99825086
111G1/S transition of mitotic cell cycle (GO:0000082)2.99825086
112regulation of nuclear cell cycle DNA replication (GO:0033262)2.99272460
113pseudouridine synthesis (GO:0001522)2.97028037
114mitotic spindle checkpoint (GO:0071174)2.96984716
115mitotic spindle assembly checkpoint (GO:0007094)2.96690986
116regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.96060771
117maturation of 5.8S rRNA (GO:0000460)2.95515931
118negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.95298781
119RNA-dependent DNA replication (GO:0006278)2.95255036
120telomere maintenance via telomere lengthening (GO:0010833)2.94190539
121ribonucleoprotein complex biogenesis (GO:0022613)2.91459250
122chromosome segregation (GO:0007059)2.90038711
123protein localization to chromosome (GO:0034502)2.89186451
124mRNA transport (GO:0051028)2.89006490
125regulation of mitotic sister chromatid separation (GO:0010965)2.87554793
126regulation of mitotic sister chromatid segregation (GO:0033047)2.87554793
127regulation of sister chromatid segregation (GO:0033045)2.87554793
128regulation of sister chromatid cohesion (GO:0007063)2.86636046
129chromatin assembly or disassembly (GO:0006333)2.85426004
130regulation of centriole replication (GO:0046599)2.82785326
131regulation of RNA export from nucleus (GO:0046831)2.81957037
132rRNA processing (GO:0006364)2.78754275
133replication fork processing (GO:0031297)2.78087443
134regulation of double-strand break repair via homologous recombination (GO:0010569)2.77181737
135histone exchange (GO:0043486)2.75713073
136mismatch repair (GO:0006298)2.74874109

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.80143000
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.58773209
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.07401184
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.99761702
5FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.30393619
6EGR1_19374776_ChIP-ChIP_THP-1_Human3.20092303
7MYC_19079543_ChIP-ChIP_MESCs_Mouse3.02851143
8* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.82588248
9MYC_19030024_ChIP-ChIP_MESCs_Mouse2.73569562
10* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.63485859
11* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.35562045
12EST1_17652178_ChIP-ChIP_JURKAT_Human2.34880564
13* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.33827729
14E2F1_21310950_ChIP-Seq_MCF-7_Human2.25187366
15KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.24816955
16AR_21909140_ChIP-Seq_LNCAP_Human2.20820777
17MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.19382637
18ETS1_20019798_ChIP-Seq_JURKAT_Human2.09612940
19MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.06487998
20* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.03580097
21NANOG_18555785_ChIP-Seq_MESCs_Mouse2.02398555
22SALL1_21062744_ChIP-ChIP_HESCs_Human2.00764792
23MYCN_18555785_ChIP-Seq_MESCs_Mouse1.98143918
24MYC_22102868_ChIP-Seq_BL_Human1.97822486
25XRN2_22483619_ChIP-Seq_HELA_Human1.95964824
26CREB1_15753290_ChIP-ChIP_HEK293T_Human1.92656758
27GABP_17652178_ChIP-ChIP_JURKAT_Human1.91707144
28* VDR_23849224_ChIP-Seq_CD4+_Human1.84718452
29POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.81069953
30* CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.80749687
31HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.77485899
32SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.77121099
33TP63_19390658_ChIP-ChIP_HaCaT_Human1.76170998
34YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.73679182
35POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.71061271
36PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.69669162
37FOXP3_21729870_ChIP-Seq_TREG_Human1.67719212
38E2F1_18555785_ChIP-Seq_MESCs_Mouse1.65878703
39KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.65605065
40KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.65605065
41KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.65605065
42CIITA_25753668_ChIP-Seq_RAJI_Human1.60138014
43TTF2_22483619_ChIP-Seq_HELA_Human1.58277518
44DCP1A_22483619_ChIP-Seq_HELA_Human1.57260727
45* GABP_19822575_ChIP-Seq_HepG2_Human1.51750383
46ELK1_19687146_ChIP-ChIP_HELA_Human1.51285428
47KDM5A_27292631_Chip-Seq_BREAST_Human1.49143244
48PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.47932430
49NOTCH1_21737748_ChIP-Seq_TLL_Human1.47553434
50THAP11_20581084_ChIP-Seq_MESCs_Mouse1.44397581
51ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.42839085
52POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.42407570
53STAT3_1855785_ChIP-Seq_MESCs_Mouse1.41773986
54SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.40589499
55E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.40498071
56MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.38385637
57NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.37247531
58SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.36176687
59NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.35560220
60SOX2_18555785_ChIP-Seq_MESCs_Mouse1.34442708
61ZFX_18555785_ChIP-Seq_MESCs_Mouse1.33399949
62* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.28630931
63PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.28387728
64ELF1_17652178_ChIP-ChIP_JURKAT_Human1.26402067
65FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.22697589
66TCF3_18692474_ChIP-Seq_MEFs_Mouse1.22476503
67KLF4_18555785_ChIP-Seq_MESCs_Mouse1.21692273
68NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.21235427
69PADI4_21655091_ChIP-ChIP_MCF-7_Human1.19130905
70ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.18697366
71NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.18146974
72HOXB4_20404135_ChIP-ChIP_EML_Mouse1.18094665
73* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.16314387
74YY1_21170310_ChIP-Seq_MESCs_Mouse1.16128225
75ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.14812664
76TFEB_21752829_ChIP-Seq_HELA_Human1.14178686
77HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.14028043
78RBPJ_22232070_ChIP-Seq_NCS_Mouse1.13527113
79SOX17_20123909_ChIP-Seq_XEN_Mouse1.12920935
80* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.12790949
81DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.12742822
82SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.12318342
83EWS_26573619_Chip-Seq_HEK293_Human1.11597235
84CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.10569744
85HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.09681509
86* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.09142242
87TCF3_18692474_ChIP-Seq_MESCs_Mouse1.07980178
88CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.06986359
89ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.06162505
90HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.05776229
91ELK1_22589737_ChIP-Seq_MCF10A_Human1.05451340
92DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.03729004
93E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.03612965
94SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.01899527
95NANOG_21062744_ChIP-ChIP_HESCs_Human1.00423113
96NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.99952590
97* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.99780628
98KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.98686869
99CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.95221826
100* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.92963409
101SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.92818598
102NANOG_16153702_ChIP-ChIP_HESCs_Human0.92718879
103KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.91636720
104CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.90465799
105SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.88312896
106SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.87432468
107* ELF5_23300383_ChIP-Seq_T47D_Human0.87318668
108ESR1_15608294_ChIP-ChIP_MCF-7_Human0.86713415
109FUS_26573619_Chip-Seq_HEK293_Human0.86555222
110SRF_21415370_ChIP-Seq_HL-1_Mouse0.85719301
111CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.85267537
112BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.84275741
113CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.82802920
114CHD1_26751641_Chip-Seq_LNCaP_Human0.82623816
115MYC_18940864_ChIP-ChIP_HL60_Human0.81472983
116CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.80784385
117ERG_20887958_ChIP-Seq_HPC-7_Mouse0.80352544
118NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.77851125
119POU5F1_16518401_ChIP-PET_MESCs_Mouse0.76343599
120* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.75641353
121POU5F1_16153702_ChIP-ChIP_HESCs_Human0.72089117
122SOX2_16153702_ChIP-ChIP_HESCs_Human0.71684910
123TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.69901432
124HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.69667809

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.72515708
2MP0010094_abnormal_chromosome_stability4.33648728
3MP0003111_abnormal_nucleus_morphology4.32714277
4MP0004957_abnormal_blastocyst_morpholog3.92932448
5MP0008057_abnormal_DNA_replication3.88886741
6MP0003077_abnormal_cell_cycle3.81276975
7MP0009697_abnormal_copulation3.08455254
8MP0008058_abnormal_DNA_repair3.03880001
9MP0010352_gastrointestinal_tract_polyps2.84980610
10MP0008007_abnormal_cellular_replicative2.80861666
11MP0000350_abnormal_cell_proliferation2.42272356
12MP0008932_abnormal_embryonic_tissue2.36538563
13MP0003123_paternal_imprinting2.36433864
14MP0002396_abnormal_hematopoietic_system2.33262513
15MP0001730_embryonic_growth_arrest2.26428369
16MP0008877_abnormal_DNA_methylation2.24285973
17MP0010307_abnormal_tumor_latency2.23133636
18MP0003806_abnormal_nucleotide_metabolis2.14984895
19MP0005076_abnormal_cell_differentiation2.09490631
20MP0001672_abnormal_embryogenesis/_devel1.92701079
21MP0005380_embryogenesis_phenotype1.92701079
22MP0003786_premature_aging1.87299181
23MP0003890_abnormal_embryonic-extraembry1.81542734
24MP0003984_embryonic_growth_retardation1.73896350
25MP0001697_abnormal_embryo_size1.71862257
26MP0002088_abnormal_embryonic_growth/wei1.69873004
27MP0002085_abnormal_embryonic_tissue1.69149505
28MP0002084_abnormal_developmental_patter1.69043001
29MP0002086_abnormal_extraembryonic_tissu1.62712069
30MP0006035_abnormal_mitochondrial_morpho1.62134091
31MP0003121_genomic_imprinting1.59381827
32MP0004808_abnormal_hematopoietic_stem1.58952406
33MP0004197_abnormal_fetal_growth/weight/1.57823276
34MP0000490_abnormal_crypts_of1.57099028
35MP0002080_prenatal_lethality1.51325904
36MP0003186_abnormal_redox_activity1.49063107
37MP0003763_abnormal_thymus_physiology1.44139254
38MP0002019_abnormal_tumor_incidence1.39458934
39MP0003718_maternal_effect1.38352397
40MP0010030_abnormal_orbit_morphology1.37615658
41MP0000313_abnormal_cell_death1.32740099
42MP0003941_abnormal_skin_development1.30439592
43MP0006036_abnormal_mitochondrial_physio1.30010304
44MP0008789_abnormal_olfactory_epithelium1.21797196
45MP0006292_abnormal_olfactory_placode1.21746652
46MP0001661_extended_life_span1.20787918
47MP0000358_abnormal_cell_content/1.20123835
48MP0003566_abnormal_cell_adhesion1.19822279
49MP0001293_anophthalmia1.18681830
50MP0002653_abnormal_ependyma_morphology1.16807159
51MP0005408_hypopigmentation1.16749910
52MP0000703_abnormal_thymus_morphology1.15050668
53MP0009333_abnormal_splenocyte_physiolog1.14434218
54MP0002210_abnormal_sex_determination1.12683026
55MP0003950_abnormal_plasma_membrane1.12034492
56MP0003567_abnormal_fetal_cardiomyocyte1.10598563
57MP0002233_abnormal_nose_morphology1.08022881
58MP0005023_abnormal_wound_healing1.07012626
59MP0002398_abnormal_bone_marrow1.06805466
60MP0002697_abnormal_eye_size1.06744564
61MP0001545_abnormal_hematopoietic_system1.06483170
62MP0005397_hematopoietic_system_phenotyp1.06483170
63MP0004233_abnormal_muscle_weight1.06176405
64MP0003705_abnormal_hypodermis_morpholog1.05607171
65MP0003315_abnormal_perineum_morphology1.01900293
66MP0000858_altered_metastatic_potential1.00806229
67MP0003221_abnormal_cardiomyocyte_apopto1.00790715
68MP0002796_impaired_skin_barrier1.00767418
69MP0005395_other_phenotype0.98091516
70MP0005501_abnormal_skin_physiology0.94747892
71MP0001119_abnormal_female_reproductive0.93357987
72MP0001145_abnormal_male_reproductive0.93233495
73MP0003787_abnormal_imprinting0.92331448
74MP0005621_abnormal_cell_physiology0.92308981
75MP0002722_abnormal_immune_system0.91690723
76MP0003119_abnormal_digestive_system0.91652815
77MP0003937_abnormal_limbs/digits/tail_de0.91598173
78MP0009053_abnormal_anal_canal0.89558508
79MP0001915_intracranial_hemorrhage0.89485666
80MP0000647_abnormal_sebaceous_gland0.89353181
81MP0000689_abnormal_spleen_morphology0.89098909
82MP0001849_ear_inflammation0.88112663
83MP0002111_abnormal_tail_morphology0.87714871
84MP0002102_abnormal_ear_morphology0.87559349
85MP0004264_abnormal_extraembryonic_tissu0.86193836
86MP0004133_heterotaxia0.86030456
87MP0005384_cellular_phenotype0.85696004
88MP0003448_altered_tumor_morphology0.85563890
89MP0002938_white_spotting0.85376214
90MP0002877_abnormal_melanocyte_morpholog0.84870953
91MP0000428_abnormal_craniofacial_morphol0.84282995
92MP0000653_abnormal_sex_gland0.82167678
93MP0000432_abnormal_head_morphology0.82000733
94MP0006072_abnormal_retinal_apoptosis0.81532715
95MP0009703_decreased_birth_body0.78600868
96MP0000749_muscle_degeneration0.78275618
97MP0005367_renal/urinary_system_phenotyp0.77904964
98MP0000516_abnormal_urinary_system0.77904964
99MP0001529_abnormal_vocalization0.76670055
100MP0002269_muscular_atrophy0.76645684
101MP0000733_abnormal_muscle_development0.75244245
102MP0001929_abnormal_gametogenesis0.75237365
103MP0005499_abnormal_olfactory_system0.73524006
104MP0005394_taste/olfaction_phenotype0.73524006
105MP0002925_abnormal_cardiovascular_devel0.72887446
106MP0002163_abnormal_gland_morphology0.72815157
107MP0009278_abnormal_bone_marrow0.72098967
108MP0001286_abnormal_eye_development0.72051578
109MP0002429_abnormal_blood_cell0.71756949
110MP0000569_abnormal_digit_pigmentation0.70702115
111MP0005330_cardiomyopathy0.70108332
112MP0010234_abnormal_vibrissa_follicle0.69778687
113MP0001853_heart_inflammation0.69162710
114MP0000762_abnormal_tongue_morphology0.68799949
115MP0009672_abnormal_birth_weight0.68552204
116MP0002405_respiratory_system_inflammati0.67531144
117MP0000627_abnormal_mammary_gland0.67253828
118MP0002234_abnormal_pharynx_morphology0.66134591
119MP0000716_abnormal_immune_system0.65983600
120MP0003755_abnormal_palate_morphology0.65870351
121MP0001800_abnormal_humoral_immune0.65253304
122MP0002132_abnormal_respiratory_system0.64712253
123MP0009250_abnormal_appendicular_skeleto0.64422678
124MP0003936_abnormal_reproductive_system0.64324168
125MP0002092_abnormal_eye_morphology0.63492541
126MP0005389_reproductive_system_phenotype0.63405602
127MP0002060_abnormal_skin_morphology0.62914626
128MP0003935_abnormal_craniofacial_develop0.62648930
129MP0005671_abnormal_response_to0.61638380
130MP0000537_abnormal_urethra_morphology0.61130698
131MP0003868_abnormal_feces_composition0.60545467
132MP0000371_diluted_coat_color0.60335898
133MP0003943_abnormal_hepatobiliary_system0.59813000
134MP0003699_abnormal_female_reproductive0.59601093
135MP0002160_abnormal_reproductive_system0.59380197
136MP0004272_abnormal_basement_membrane0.58984310
137MP0001299_abnormal_eye_distance/0.58386610
138MP0001881_abnormal_mammary_gland0.58294544
139MP0001727_abnormal_embryo_implantation0.58020602
140MP0002006_tumorigenesis0.57586102
141MP0002161_abnormal_fertility/fecundity0.56331420
142MP0002075_abnormal_coat/hair_pigmentati0.55997201
143MP0001764_abnormal_homeostasis0.55357424
144MP0001919_abnormal_reproductive_system0.55250334
145MP0002751_abnormal_autonomic_nervous0.55000738

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)4.23507775
2Birth length less than 3rd percentile (HP:0003561)4.18680207
3Chromosomal breakage induced by crosslinking agents (HP:0003221)4.01888052
4Abnormality of the labia minora (HP:0012880)3.70067020
5Selective tooth agenesis (HP:0001592)3.30909584
6Patellar aplasia (HP:0006443)3.25248212
7Ependymoma (HP:0002888)3.25020301
8Abnormality of chromosome stability (HP:0003220)3.21977647
9Medulloblastoma (HP:0002885)3.21384832
10Multiple enchondromatosis (HP:0005701)3.14352989
11Increased serum pyruvate (HP:0003542)3.12370565
12Aplasia/Hypoplasia of the uvula (HP:0010293)3.07172492
13Meckel diverticulum (HP:0002245)3.05979723
14Breast hypoplasia (HP:0003187)3.01133610
15Absent radius (HP:0003974)2.99331954
16Aplasia/Hypoplasia of the patella (HP:0006498)2.99060630
17Abnormality of glycolysis (HP:0004366)2.98214403
18Abnormality of the ileum (HP:0001549)2.94920570
19Microvesicular hepatic steatosis (HP:0001414)2.94782884
20Agnosia (HP:0010524)2.91026145
21Abnormality of the preputium (HP:0100587)2.86913209
22Aplasia involving forearm bones (HP:0009822)2.83285006
23Absent forearm bone (HP:0003953)2.83285006
24Acute necrotizing encephalopathy (HP:0006965)2.78069386
25Ectopic kidney (HP:0000086)2.77155496
26Acute encephalopathy (HP:0006846)2.73590539
27Embryonal renal neoplasm (HP:0011794)2.70165530
28Degeneration of anterior horn cells (HP:0002398)2.68211126
29Abnormality of the anterior horn cell (HP:0006802)2.68211126
30Increased CSF lactate (HP:0002490)2.65646169
31Abnormality of methionine metabolism (HP:0010901)2.64331042
32Impulsivity (HP:0100710)2.63099681
33Myelodysplasia (HP:0002863)2.61441983
34Increased hepatocellular lipid droplets (HP:0006565)2.59255602
35Rhabdomyosarcoma (HP:0002859)2.58969887
36Abnormality of the astrocytes (HP:0100707)2.49753345
37Astrocytoma (HP:0009592)2.49753345
38Colon cancer (HP:0003003)2.49088092
39Small intestinal stenosis (HP:0012848)2.46428605
40Duodenal stenosis (HP:0100867)2.46428605
41Absent thumb (HP:0009777)2.44641766
42Reduced antithrombin III activity (HP:0001976)2.44594300
43Abnormal number of incisors (HP:0011064)2.43058008
44Abnormal mitochondria in muscle tissue (HP:0008316)2.42884805
45Increased serum lactate (HP:0002151)2.40383499
46Cerebral edema (HP:0002181)2.39061933
47Glioma (HP:0009733)2.39037336
48Carpal bone hypoplasia (HP:0001498)2.38665425
49Microglossia (HP:0000171)2.36137329
50Lipid accumulation in hepatocytes (HP:0006561)2.34624582
51Facial cleft (HP:0002006)2.30971742
52Supernumerary spleens (HP:0009799)2.28874323
53Deviation of the thumb (HP:0009603)2.27728490
54Neoplasm of the oral cavity (HP:0100649)2.27661631
55Oral leukoplakia (HP:0002745)2.25383545
56Volvulus (HP:0002580)2.25268016
57Progressive macrocephaly (HP:0004481)2.24404464
58Amaurosis fugax (HP:0100576)2.20806489
59Postnatal microcephaly (HP:0005484)2.19895421
60Basal cell carcinoma (HP:0002671)2.18923734
61Sloping forehead (HP:0000340)2.14280939
62Proximal placement of thumb (HP:0009623)2.13440915
63Rough bone trabeculation (HP:0100670)2.12225627
64Facial hemangioma (HP:0000329)2.11782659
65Bone marrow hypocellularity (HP:0005528)2.11071743
66Mitochondrial inheritance (HP:0001427)2.11051458
67Rib fusion (HP:0000902)2.10364091
68Secondary amenorrhea (HP:0000869)2.10314791
69Abnormality of the duodenum (HP:0002246)2.08937658
70Long eyelashes (HP:0000527)2.07459385
71Abnormality of the carotid arteries (HP:0005344)2.06597521
72Aplasia/Hypoplasia of the sternum (HP:0006714)2.06561103
73Cafe-au-lait spot (HP:0000957)2.04222624
74Tracheoesophageal fistula (HP:0002575)2.03908733
75Short middle phalanx of the 5th finger (HP:0004220)2.03639603
76Increased nuchal translucency (HP:0010880)2.03554373
77Type I transferrin isoform profile (HP:0003642)2.02876823
78Abnormality of the fingertips (HP:0001211)2.02748872
79Cerebral hypomyelination (HP:0006808)2.02512796
80Premature graying of hair (HP:0002216)2.01976482
81Reticulocytopenia (HP:0001896)2.01921775
82Aplasia/hypoplasia of the humerus (HP:0006507)2.01648984
83Prominent nose (HP:0000448)2.00641792
84Premature ovarian failure (HP:0008209)2.00282397
85Bifid tongue (HP:0010297)1.99840777
86Short thumb (HP:0009778)1.97257431
87Progressive muscle weakness (HP:0003323)1.96014784
88Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.95429642
89Neoplasm of striated muscle (HP:0009728)1.95179327
90Clubbing of toes (HP:0100760)1.94964291
91Hepatocellular necrosis (HP:0001404)1.94628651
92Missing ribs (HP:0000921)1.94291167
93Decreased activity of mitochondrial respiratory chain (HP:0008972)1.94001636
94Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.94001636
95Choanal atresia (HP:0000453)1.93431619
96Pancreatic islet-cell hyperplasia (HP:0004510)1.93072094
97Aplastic anemia (HP:0001915)1.91667637
98Neoplasm of the colon (HP:0100273)1.91140786
99Abnormality of the pons (HP:0007361)1.91069102
100Neoplasm of the pancreas (HP:0002894)1.90620786
101Abnormal umbilical cord blood vessels (HP:0011403)1.87348193
102Single umbilical artery (HP:0001195)1.87348193
103Abnormality of the fetal cardiovascular system (HP:0010948)1.87348193
104Intestinal fistula (HP:0100819)1.86634545
105Aplasia/Hypoplasia of the sacrum (HP:0008517)1.86285469
106Squamous cell carcinoma (HP:0002860)1.85609824
107Lactic acidosis (HP:0003128)1.85597917
108Anal stenosis (HP:0002025)1.85259006
109Triphalangeal thumb (HP:0001199)1.84808326
11011 pairs of ribs (HP:0000878)1.84675489
111Abnormality of alanine metabolism (HP:0010916)1.84513732
112Hyperalaninemia (HP:0003348)1.84513732
113Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.84513732
114Horseshoe kidney (HP:0000085)1.84010879
115Posterior subcapsular cataract (HP:0007787)1.83920618
116Supernumerary bones of the axial skeleton (HP:0009144)1.83554761
117Abnormality of the umbilical cord (HP:0010881)1.83548097
118Progressive external ophthalmoplegia (HP:0000590)1.83344631
119Abdominal situs inversus (HP:0003363)1.82109838
120Abnormality of abdominal situs (HP:0011620)1.82109838
121Acute myeloid leukemia (HP:0004808)1.82101303
122Short humerus (HP:0005792)1.82047476
123Abnormalities of placenta or umbilical cord (HP:0001194)1.80494509
124Atresia of the external auditory canal (HP:0000413)1.80408720
125Hypoplasia of the pons (HP:0012110)1.79964927
126Shawl scrotum (HP:0000049)1.79432748
127Abnormality of DNA repair (HP:0003254)1.79386602
128Spinal muscular atrophy (HP:0007269)1.79383634
129Hepatic necrosis (HP:0002605)1.79339758
130Abnormality of serum amino acid levels (HP:0003112)1.78792305
131Lymphoma (HP:0002665)1.78622837
132Cortical dysplasia (HP:0002539)1.77464842
133Supernumerary ribs (HP:0005815)1.77027540
134Abnormality of aspartate family amino acid metabolism (HP:0010899)1.76232669
135Duplicated collecting system (HP:0000081)1.76012552
136Macrocytic anemia (HP:0001972)1.75840512
137Slender long bone (HP:0003100)1.74981764
138Rectal fistula (HP:0100590)1.74653434
139Rectovaginal fistula (HP:0000143)1.74653434
140Esophageal atresia (HP:0002032)1.74541608
141Nephroblastoma (Wilms tumor) (HP:0002667)1.72637313
142Trismus (HP:0000211)1.72012186
143Biliary tract neoplasm (HP:0100574)1.71189978
144Abnormal lung lobation (HP:0002101)1.70744707
145Spastic diplegia (HP:0001264)1.70353951
146Urethral obstruction (HP:0000796)1.70286849
147Sparse lateral eyebrow (HP:0005338)1.70123086
148Pancytopenia (HP:0001876)1.70033559
149Sensory axonal neuropathy (HP:0003390)1.69069597
150Skull defect (HP:0001362)1.68886306
151Abnormal protein N-linked glycosylation (HP:0012347)1.68411086
152Abnormal glycosylation (HP:0012345)1.68411086
153Malignant gastrointestinal tract tumors (HP:0006749)1.68156698
154Gastrointestinal carcinoma (HP:0002672)1.68156698
155Deep philtrum (HP:0002002)1.67455518
156Abnormality of the renal collecting system (HP:0004742)1.65298279
157Oligodactyly (HP:0012165)1.65269837
158Breast aplasia (HP:0100783)1.64448546
159High pitched voice (HP:0001620)1.63627228

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.34019603
2CDK123.90475032
3PBK3.44508114
4TSSK63.10634835
5BUB13.08690403
6WEE13.08151193
7MST42.97739501
8TTK2.69012793
9EIF2AK12.56161499
10NEK22.48645052
11NEK12.39479972
12SRPK12.27538183
13EPHA22.14433344
14PLK42.04068707
15STK162.02414530
16PLK12.00402125
17PLK31.96241702
18TRIM281.93322802
19ATR1.87253392
20CDK71.86336521
21STK101.81162166
22MKNK11.79922257
23VRK21.78535958
24MKNK21.70097951
25BRD41.65973265
26EEF2K1.65862493
27RPS6KA41.63585161
28BRSK21.62769005
29CHEK21.61067478
30AURKB1.58758259
31RPS6KB21.58048457
32CHEK11.49785913
33NME11.47829174
34CDK41.46145852
35PDK21.46137464
36AKT31.45419004
37ACVR1B1.44573371
38ALK1.41111303
39ZAK1.40753427
40STK38L1.40001886
41LATS21.38850352
42PASK1.38570857
43MAP3K81.36608964
44LATS11.35765864
45NUAK11.33421758
46STK31.33032098
47PIM11.28159534
48CDK81.17912103
49ATM1.16767293
50TAF11.14319897
51MELK1.09595808
52TESK21.08386395
53EIF2AK31.07952915
54CDK21.05618733
55PNCK1.05206682
56VRK11.01661121
57BRSK11.01434052
58MAP4K11.00999316
59TNIK1.00675559
60AURKA0.97314005
61TXK0.95777585
62TGFBR10.92503966
63STK40.91545526
64CDK60.90550366
65CHUK0.88791620
66MST1R0.87802193
67CLK10.85702260
68PAK40.85191353
69MAP3K100.82659252
70MTOR0.80248491
71BMPR1B0.80098811
72TLK10.77349536
73CDK10.77272171
74SCYL20.77060945
75ERBB30.76405347
76JAK30.74219143
77FLT30.69614884
78PIM20.66038230
79CSNK2A20.63180373
80TAOK20.63027826
81NME20.60155391
82BCR0.60151057
83DYRK30.57534142
84EIF2AK20.56584080
85WNK30.55839068
86CSNK1G10.55149097
87MAP3K120.53592282
88FGFR10.51713240
89MAP3K140.50987427
90YES10.50692168
91IKBKB0.50036065
92PRKCI0.49465505
93CSNK1E0.48691564
94MAPK140.48091850
95CSNK2A10.47666042
96MET0.47182707
97PKN20.47179768
98DMPK0.45168878
99ILK0.45136883
100PAK10.44784734
101CSNK1D0.44682317
102STK390.44106087
103PRKDC0.43099099
104CDK90.42904818
105CSNK1G30.42649723
106ZAP700.41308840
107CSNK1A1L0.37634602
108ERBB40.37184975
109STK240.36693668
110MAP2K70.35535910
111RPS6KB10.34611119
112NEK60.34197212
113GSK3B0.34107369
114MAPK10.34084184
115MAP3K60.33837010
116AKT10.33656291
117CCNB10.33594496
118MAP3K110.33405594
119BRAF0.33143399
120BMX0.33083551
121NLK0.33055850
122MARK30.32852882
123MAP3K50.32297120
124PAK20.32050752
125CDK30.30038170
126AKT20.29967014
127RPS6KA50.27998082
128PLK20.27410974
129MAP2K30.27186582
130TRPM70.24003084
131SMG10.23509455

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.02323035
2DNA replication_Homo sapiens_hsa030303.87818002
3Mismatch repair_Homo sapiens_hsa034303.67833157
4RNA transport_Homo sapiens_hsa030133.22652108
5Spliceosome_Homo sapiens_hsa030403.01120149
6Cell cycle_Homo sapiens_hsa041102.89661188
7One carbon pool by folate_Homo sapiens_hsa006702.87575073
8Homologous recombination_Homo sapiens_hsa034402.76732224
9Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.62120724
10RNA polymerase_Homo sapiens_hsa030202.60903742
11Base excision repair_Homo sapiens_hsa034102.60823576
12Nucleotide excision repair_Homo sapiens_hsa034202.49638071
13Fanconi anemia pathway_Homo sapiens_hsa034602.43439175
14Protein export_Homo sapiens_hsa030602.39086971
15Non-homologous end-joining_Homo sapiens_hsa034502.08392784
16mRNA surveillance pathway_Homo sapiens_hsa030152.08128710
17RNA degradation_Homo sapiens_hsa030182.05279503
18Basal transcription factors_Homo sapiens_hsa030222.03053033
19p53 signaling pathway_Homo sapiens_hsa041151.83448552
20Proteasome_Homo sapiens_hsa030501.77644435
21Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.71471957
22Pyrimidine metabolism_Homo sapiens_hsa002401.69459680
23Propanoate metabolism_Homo sapiens_hsa006401.60586089
24Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.35847529
25Ribosome_Homo sapiens_hsa030101.34941051
26Epstein-Barr virus infection_Homo sapiens_hsa051691.31567209
27Pyruvate metabolism_Homo sapiens_hsa006201.30303275
28Herpes simplex infection_Homo sapiens_hsa051681.29073574
29Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.28894112
30Parkinsons disease_Homo sapiens_hsa050121.27179063
31Fatty acid elongation_Homo sapiens_hsa000621.26091762
322-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.25944053
33Viral carcinogenesis_Homo sapiens_hsa052031.23119520
34Oxidative phosphorylation_Homo sapiens_hsa001901.22371885
35Steroid biosynthesis_Homo sapiens_hsa001001.19454167
36Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.18795932
37Antigen processing and presentation_Homo sapiens_hsa046121.15100640
38MicroRNAs in cancer_Homo sapiens_hsa052061.13217444
39Huntingtons disease_Homo sapiens_hsa050161.11655024
40Carbon metabolism_Homo sapiens_hsa012001.11123723
41Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.08765885
42HTLV-I infection_Homo sapiens_hsa051661.08386448
43Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.07607561
44Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.05357430
45Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.02378363
46Folate biosynthesis_Homo sapiens_hsa007901.01502534
47NF-kappa B signaling pathway_Homo sapiens_hsa040641.01334255
48Small cell lung cancer_Homo sapiens_hsa052220.93811735
49Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.90698958
50Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.90049967
51TGF-beta signaling pathway_Homo sapiens_hsa043500.89531247
52Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.89428718
53Oocyte meiosis_Homo sapiens_hsa041140.89101017
54Purine metabolism_Homo sapiens_hsa002300.87658277
55Measles_Homo sapiens_hsa051620.87158980
56Legionellosis_Homo sapiens_hsa051340.86221387
57Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.85716297
58Adherens junction_Homo sapiens_hsa045200.84944409
59Transcriptional misregulation in cancer_Homo sapiens_hsa052020.84027897
60Systemic lupus erythematosus_Homo sapiens_hsa053220.83582953
61Hippo signaling pathway_Homo sapiens_hsa043900.83342272
62Glutathione metabolism_Homo sapiens_hsa004800.82173083
63Notch signaling pathway_Homo sapiens_hsa043300.81594818
64Thyroid cancer_Homo sapiens_hsa052160.81408207
65Primary immunodeficiency_Homo sapiens_hsa053400.80696625
66Colorectal cancer_Homo sapiens_hsa052100.76395607
67Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.76348001
68Graft-versus-host disease_Homo sapiens_hsa053320.73134709
69Fatty acid metabolism_Homo sapiens_hsa012120.72759112
70Hepatitis B_Homo sapiens_hsa051610.72511381
71Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.69719165
72Apoptosis_Homo sapiens_hsa042100.69677657
73NOD-like receptor signaling pathway_Homo sapiens_hsa046210.67950822
74Allograft rejection_Homo sapiens_hsa053300.67588919
75Viral myocarditis_Homo sapiens_hsa054160.66158447
76Chronic myeloid leukemia_Homo sapiens_hsa052200.65941423
77Basal cell carcinoma_Homo sapiens_hsa052170.65101461
78Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.64249322
79Alzheimers disease_Homo sapiens_hsa050100.62840436
80Influenza A_Homo sapiens_hsa051640.61840756
81Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.61138769
82Shigellosis_Homo sapiens_hsa051310.60578854
83N-Glycan biosynthesis_Homo sapiens_hsa005100.59988570
84Selenocompound metabolism_Homo sapiens_hsa004500.59639465
85mTOR signaling pathway_Homo sapiens_hsa041500.59445617
86Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.58583861
87Lysine degradation_Homo sapiens_hsa003100.58510853
88Hematopoietic cell lineage_Homo sapiens_hsa046400.58121695
89Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.57005481
90Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.56957080
91Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.56859104
92Intestinal immune network for IgA production_Homo sapiens_hsa046720.56470030
93Metabolic pathways_Homo sapiens_hsa011000.56098173
94Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.55602425
95Sulfur relay system_Homo sapiens_hsa041220.53404113
96Acute myeloid leukemia_Homo sapiens_hsa052210.53000579
97Prostate cancer_Homo sapiens_hsa052150.52103024
98Type I diabetes mellitus_Homo sapiens_hsa049400.50942385
99Bladder cancer_Homo sapiens_hsa052190.50050109
100RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.49671396
101Cysteine and methionine metabolism_Homo sapiens_hsa002700.49174587
102Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.48914584
103Pancreatic cancer_Homo sapiens_hsa052120.48642514
104Pentose and glucuronate interconversions_Homo sapiens_hsa000400.48413111
105Fatty acid degradation_Homo sapiens_hsa000710.47994340
106T cell receptor signaling pathway_Homo sapiens_hsa046600.47975001
107Arginine and proline metabolism_Homo sapiens_hsa003300.47605692
108Pathways in cancer_Homo sapiens_hsa052000.47528163
109Jak-STAT signaling pathway_Homo sapiens_hsa046300.47347830
110Cyanoamino acid metabolism_Homo sapiens_hsa004600.46465986
111Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.45156528
112Butanoate metabolism_Homo sapiens_hsa006500.44963376
113Biosynthesis of amino acids_Homo sapiens_hsa012300.44596561
114Leishmaniasis_Homo sapiens_hsa051400.44489330
115HIF-1 signaling pathway_Homo sapiens_hsa040660.44410347
116Vitamin B6 metabolism_Homo sapiens_hsa007500.43424140
117TNF signaling pathway_Homo sapiens_hsa046680.43169157
118Endometrial cancer_Homo sapiens_hsa052130.38655645
119Drug metabolism - other enzymes_Homo sapiens_hsa009830.37481211
120Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.36852527
121Autoimmune thyroid disease_Homo sapiens_hsa053200.36728445
122Proteoglycans in cancer_Homo sapiens_hsa052050.36317667
123beta-Alanine metabolism_Homo sapiens_hsa004100.35472244
124Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.35407663
125Wnt signaling pathway_Homo sapiens_hsa043100.35238596
126Thyroid hormone signaling pathway_Homo sapiens_hsa049190.35179643
127Pentose phosphate pathway_Homo sapiens_hsa000300.34855612
128Toxoplasmosis_Homo sapiens_hsa051450.34634208
129FoxO signaling pathway_Homo sapiens_hsa040680.34473783
130Central carbon metabolism in cancer_Homo sapiens_hsa052300.33562006
131Sulfur metabolism_Homo sapiens_hsa009200.31869303
132Hedgehog signaling pathway_Homo sapiens_hsa043400.31868690
133Asthma_Homo sapiens_hsa053100.31603407
134Melanoma_Homo sapiens_hsa052180.30441596
135PI3K-Akt signaling pathway_Homo sapiens_hsa041510.29690704
136Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.28091780
137AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.28075428
138Peroxisome_Homo sapiens_hsa041460.27521183
139Regulation of actin cytoskeleton_Homo sapiens_hsa048100.27485080
140Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.26583433
141Non-small cell lung cancer_Homo sapiens_hsa052230.26525572
142Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.26520339
143Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.25415983
144Vitamin digestion and absorption_Homo sapiens_hsa049770.19606638
145Alcoholism_Homo sapiens_hsa050340.17958282
146Fatty acid biosynthesis_Homo sapiens_hsa000610.17402258
147Regulation of autophagy_Homo sapiens_hsa041400.15536845
148Tight junction_Homo sapiens_hsa045300.14408382
149Fructose and mannose metabolism_Homo sapiens_hsa000510.14164323
150Galactose metabolism_Homo sapiens_hsa000520.14052474
151Steroid hormone biosynthesis_Homo sapiens_hsa001400.11976535
152Primary bile acid biosynthesis_Homo sapiens_hsa001200.09721991
153Tryptophan metabolism_Homo sapiens_hsa003800.07292390

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