NOL12

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1maturation of SSU-rRNA (GO:0030490)5.60166594
2ribosomal small subunit biogenesis (GO:0042274)5.48747852
3ribosomal small subunit assembly (GO:0000028)5.47045324
4viral transcription (GO:0019083)5.32422931
5translational termination (GO:0006415)5.21166920
6DNA deamination (GO:0045006)5.00663713
7ribosomal large subunit biogenesis (GO:0042273)4.89050317
8proteasome assembly (GO:0043248)4.79864630
9SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.72546534
10cotranslational protein targeting to membrane (GO:0006613)4.65975438
11protein targeting to ER (GO:0045047)4.62607635
12ribonucleoprotein complex biogenesis (GO:0022613)4.56735727
13translational elongation (GO:0006414)4.56249002
14translational initiation (GO:0006413)4.56067815
15termination of RNA polymerase III transcription (GO:0006386)4.48833446
16transcription elongation from RNA polymerase III promoter (GO:0006385)4.48833446
17protein localization to endoplasmic reticulum (GO:0070972)4.40166399
18establishment of protein localization to endoplasmic reticulum (GO:0072599)4.39953568
19formation of translation preinitiation complex (GO:0001731)4.38117466
20protein complex biogenesis (GO:0070271)4.27537053
21mitochondrial respiratory chain complex I assembly (GO:0032981)4.19018626
22NADH dehydrogenase complex assembly (GO:0010257)4.19018626
23mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.19018626
24nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.16910524
25ribosome biogenesis (GO:0042254)4.16785317
26cellular protein complex disassembly (GO:0043624)4.13458015
27rRNA processing (GO:0006364)4.11399888
28DNA replication checkpoint (GO:0000076)4.10076295
297-methylguanosine mRNA capping (GO:0006370)4.07876829
30mitochondrial respiratory chain complex assembly (GO:0033108)4.07843379
31viral life cycle (GO:0019058)4.07394147
32translation (GO:0006412)4.04011830
33ATP synthesis coupled proton transport (GO:0015986)4.00522893
34energy coupled proton transport, down electrochemical gradient (GO:0015985)4.00522893
35RNA capping (GO:0036260)3.99843770
367-methylguanosine RNA capping (GO:0009452)3.99843770
37negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.98269143
38rRNA metabolic process (GO:0016072)3.97185271
39DNA strand elongation involved in DNA replication (GO:0006271)3.95679504
40spliceosomal snRNP assembly (GO:0000387)3.94603899
41chaperone-mediated protein transport (GO:0072321)3.92143933
42purine deoxyribonucleotide catabolic process (GO:0009155)3.92115215
43telomere maintenance via semi-conservative replication (GO:0032201)3.87118274
44deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.85452198
45rRNA modification (GO:0000154)3.81719901
46positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.81091455
47pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.78541832
48nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.77495497
49ribosome assembly (GO:0042255)3.77492389
50anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.77473766
51purine nucleobase biosynthetic process (GO:0009113)3.77237793
52cellular component biogenesis (GO:0044085)3.77207380
53regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.76157072
54base-excision repair, AP site formation (GO:0006285)3.75752710
55DNA strand elongation (GO:0022616)3.74861042
56negative regulation of ligase activity (GO:0051352)3.71188549
57negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.71188549
58L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.71149569
59nucleobase biosynthetic process (GO:0046112)3.70820440
60pseudouridine synthesis (GO:0001522)3.69579853
61mitotic metaphase plate congression (GO:0007080)3.69301771
62cullin deneddylation (GO:0010388)3.69278423
63termination of RNA polymerase I transcription (GO:0006363)3.68719325
64exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.68391003
65transcription elongation from RNA polymerase I promoter (GO:0006362)3.67913859
66mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.65391235
67transcription from RNA polymerase I promoter (GO:0006360)3.64399473
68deoxyribonucleotide catabolic process (GO:0009264)3.63678076
69protein complex disassembly (GO:0043241)3.61988451
70spliceosomal complex assembly (GO:0000245)3.61779955
71DNA replication initiation (GO:0006270)3.61771342
72protein deneddylation (GO:0000338)3.55982584
73respiratory chain complex IV assembly (GO:0008535)3.53331891
74transcription-coupled nucleotide-excision repair (GO:0006283)3.52568417
75macromolecular complex disassembly (GO:0032984)3.48838430
76DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.48107011
77rRNA methylation (GO:0031167)3.47935162
78cytochrome complex assembly (GO:0017004)3.47218539
79signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.45887718
80signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.45887718
81signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.45887718
82telomere maintenance via recombination (GO:0000722)3.45519901
83regulation of cellular amino acid metabolic process (GO:0006521)3.45445236
84deoxyribose phosphate catabolic process (GO:0046386)3.44115556
85signal transduction involved in DNA integrity checkpoint (GO:0072401)3.44001925
86signal transduction involved in DNA damage checkpoint (GO:0072422)3.44001925
87CENP-A containing nucleosome assembly (GO:0034080)3.42703231
88signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.41897330
89intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.41897330
90signal transduction involved in cell cycle checkpoint (GO:0072395)3.38724314
91protein targeting to mitochondrion (GO:0006626)3.35924646
92chromatin remodeling at centromere (GO:0031055)3.35171201
93positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.34329836
94respiratory electron transport chain (GO:0022904)3.32931217
95establishment of protein localization to mitochondrial membrane (GO:0090151)3.29802578
96electron transport chain (GO:0022900)3.29155125
97guanosine-containing compound biosynthetic process (GO:1901070)3.27577510
98maturation of 5.8S rRNA (GO:0000460)3.27385000
99nuclear-transcribed mRNA catabolic process (GO:0000956)3.23289920
100peptidyl-histidine modification (GO:0018202)3.21787002
101antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.21117377
102positive regulation of ligase activity (GO:0051351)3.20321638
103mitotic recombination (GO:0006312)3.19423324
104viral mRNA export from host cell nucleus (GO:0046784)3.18199785
105kinetochore assembly (GO:0051382)3.16438655
106mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.16403203
107metaphase plate congression (GO:0051310)3.15824157
108transcription initiation from RNA polymerase I promoter (GO:0006361)3.15300406
109deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.15132100
110purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)3.15074727
111ncRNA processing (GO:0034470)3.14232803
112establishment of integrated proviral latency (GO:0075713)3.13794990
113transcription elongation from RNA polymerase II promoter (GO:0006368)3.12875271
114establishment of protein localization to mitochondrion (GO:0072655)3.12633183
115regulation of mitochondrial translation (GO:0070129)3.12148373
116L-methionine salvage (GO:0071267)3.11008408
117L-methionine biosynthetic process (GO:0071265)3.11008408
118amino acid salvage (GO:0043102)3.11008408
119telomere maintenance via telomere lengthening (GO:0010833)3.10805027
120purine deoxyribonucleotide metabolic process (GO:0009151)3.10579382
121negative regulation of B cell apoptotic process (GO:0002903)3.10310530
122regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.10258335
123GTP biosynthetic process (GO:0006183)3.09703824
124pyrimidine nucleotide catabolic process (GO:0006244)3.09043270
125mRNA catabolic process (GO:0006402)3.07370479
126positive regulation of viral transcription (GO:0050434)3.06948344
127DNA damage response, detection of DNA damage (GO:0042769)3.06169514
128ncRNA metabolic process (GO:0034660)3.06114880
129protein neddylation (GO:0045116)3.05671218
130tRNA processing (GO:0008033)3.04284418
131iron-sulfur cluster assembly (GO:0016226)3.01884235
132metallo-sulfur cluster assembly (GO:0031163)3.01884235
1332-deoxyribonucleotide metabolic process (GO:0009394)2.97421901
134protein localization to mitochondrion (GO:0070585)2.94033406
135DNA catabolic process, exonucleolytic (GO:0000738)2.92774459
136tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.86284511
137RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.86284511
138antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.83440123
139pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.81228078
140replication fork processing (GO:0031297)2.78745575
141tRNA modification (GO:0006400)2.78709683
142deoxyribose phosphate metabolic process (GO:0019692)2.77614809
143DNA double-strand break processing (GO:0000729)2.74976044
144UTP biosynthetic process (GO:0006228)2.73505885
145RNA phosphodiester bond hydrolysis, endonucleolytic (GO:0090502)2.72679225
146mitochondrial RNA metabolic process (GO:0000959)2.66270817

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.26964258
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.53141790
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.35826490
4* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.95715641
5GABP_17652178_ChIP-ChIP_JURKAT_Human3.91320051
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.88005561
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.76226265
8* ETS1_20019798_ChIP-Seq_JURKAT_Human3.75725445
9NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.34268595
10CREB1_15753290_ChIP-ChIP_HEK293T_Human3.25778817
11* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.23313988
12E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.22104551
13SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.21103111
14MYC_19079543_ChIP-ChIP_MESCs_Mouse3.19336721
15HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.00974345
16* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.96123286
17CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.89642737
18E2F4_17652178_ChIP-ChIP_JURKAT_Human2.75786539
19FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.75432761
20CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.69407809
21* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.60536194
22XRN2_22483619_ChIP-Seq_HELA_Human2.60207799
23* VDR_23849224_ChIP-Seq_CD4+_Human2.58351753
24BP1_19119308_ChIP-ChIP_Hs578T_Human2.52975029
25DCP1A_22483619_ChIP-Seq_HELA_Human2.47112895
26FOXM1_23109430_ChIP-Seq_U2OS_Human2.46094059
27ELF1_17652178_ChIP-ChIP_JURKAT_Human2.44750407
28CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.25211483
29E2F1_18555785_ChIP-Seq_MESCs_Mouse2.23885138
30THAP11_20581084_ChIP-Seq_MESCs_Mouse2.22991812
31YY1_21170310_ChIP-Seq_MESCs_Mouse2.19214918
32* FOXP3_21729870_ChIP-Seq_TREG_Human2.18826338
33NELFA_20434984_ChIP-Seq_ESCs_Mouse2.17242968
34MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.14716025
35* GABP_19822575_ChIP-Seq_HepG2_Human2.13114561
36IRF8_22096565_ChIP-ChIP_GC-B_Human2.12731105
37* TTF2_22483619_ChIP-Seq_HELA_Human2.09989742
38FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.04824997
39SRF_21415370_ChIP-Seq_HL-1_Mouse1.96261115
40MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.84613565
41ELK1_19687146_ChIP-ChIP_HELA_Human1.84458093
42POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.83786638
43* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.80861471
44FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.77096019
45NANOG_18555785_ChIP-Seq_MESCs_Mouse1.74447675
46MYCN_18555785_ChIP-Seq_MESCs_Mouse1.74248816
47ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.71049434
48PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.65131397
49YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.60139479
50* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.59026233
51PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.51535506
52* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.50274467
53CIITA_25753668_ChIP-Seq_RAJI_Human1.49276752
54HOXB4_20404135_ChIP-ChIP_EML_Mouse1.44829190
55BCL6_27268052_Chip-Seq_Bcells_Human1.41888104
56NOTCH1_21737748_ChIP-Seq_TLL_Human1.40692402
57ELK1_22589737_ChIP-Seq_MCF10A_Human1.40009030
58IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.39355272
59CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.38095086
60ZFX_18555785_ChIP-Seq_MESCs_Mouse1.37038818
61KDM5A_27292631_Chip-Seq_BREAST_Human1.36187613
62AR_21909140_ChIP-Seq_LNCAP_Human1.35885882
63E2F1_21310950_ChIP-Seq_MCF-7_Human1.35297839
64* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.34672800
65* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.32548516
66CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.32396141
67VDR_21846776_ChIP-Seq_THP-1_Human1.31845981
68TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.31480821
69MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.30778879
70* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.30039670
71ELF1_20517297_ChIP-Seq_JURKAT_Human1.29831517
72RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.28786006
73CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.28241076
74RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.26206422
75* POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.21930733
76BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.21331422
77MYC_18940864_ChIP-ChIP_HL60_Human1.18849595
78* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.18130770
79MAF_26560356_Chip-Seq_TH2_Human1.16794658
80KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.15234075
81TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.13802331
82TET1_21451524_ChIP-Seq_MESCs_Mouse1.12584616
83E2F1_20622854_ChIP-Seq_HELA_Human1.12533538
84DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.10781424
85BCOR_27268052_Chip-Seq_Bcells_Human1.09673454
86STAT4_19710469_ChIP-ChIP_TH1__Mouse1.08773942
87IRF8_21731497_ChIP-ChIP_J774_Mouse1.07336414
88* CTCF_26484167_Chip-Seq_Bcells_Mouse1.06077894
89SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.06028450
90E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.04730782
91SRY_22984422_ChIP-ChIP_TESTIS_Rat1.04416991
92SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.02527034
93CTCF_20526341_ChIP-Seq_ESCs_Human1.01518387
94KLF4_18555785_ChIP-Seq_MESCs_Mouse1.01045691
95TFEB_21752829_ChIP-Seq_HELA_Human1.00696695
96P68_20966046_ChIP-Seq_HELA_Human1.00645009
97PADI4_21655091_ChIP-ChIP_MCF-7_Human1.00558550
98ERA_21632823_ChIP-Seq_H3396_Human0.99579700
99STAT3_1855785_ChIP-Seq_MESCs_Mouse0.98572489
100NANOG_20526341_ChIP-Seq_ESCs_Human0.98560905
101PHF8_20622854_ChIP-Seq_HELA_Human0.98301675
102IRF1_19129219_ChIP-ChIP_H3396_Human0.98111424
103TP63_19390658_ChIP-ChIP_HaCaT_Human0.97545475
104MYB_26560356_Chip-Seq_TH2_Human0.97321642
105ZNF274_21170338_ChIP-Seq_K562_Hela0.94286598
106PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.94013863
107CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.93568112
108MYC_22102868_ChIP-Seq_BL_Human0.91337804
109P300_27268052_Chip-Seq_Bcells_Human0.91188674
110POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.91150097
111GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.90112197
112YY1_22570637_ChIP-Seq_MALME-3M_Human0.89233091
113* HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.88954585
114* SPI1_23547873_ChIP-Seq_NB4_Human0.87764611
115SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.87676339
116* KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.87252154
117CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.84649032
118CTCF_18555785_ChIP-Seq_MESCs_Mouse0.84094717
119* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.84058186
120KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.83117569
121SOX2_18555785_ChIP-Seq_MESCs_Mouse0.79021222
122OCT4_18692474_ChIP-Seq_MEFs_Mouse0.78864948
123HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.78640009
124DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.75682657
125CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.75671842
126FOXP1_21924763_ChIP-Seq_HESCs_Human0.74190866
127EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.73021896
128SOX17_20123909_ChIP-Seq_XEN_Mouse0.73009412
129SOX2_18692474_ChIP-Seq_MEFs_Mouse0.71381951
130CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.69585225
131NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.69508291

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching6.39679813
2MP0004957_abnormal_blastocyst_morpholog4.50559154
3MP0003111_abnormal_nucleus_morphology4.28220443
4MP0010094_abnormal_chromosome_stability3.80972162
5MP0003077_abnormal_cell_cycle3.61364752
6MP0008058_abnormal_DNA_repair3.42945335
7MP0008057_abnormal_DNA_replication3.34162696
8MP0008932_abnormal_embryonic_tissue3.26398389
9MP0001835_abnormal_antigen_presentation2.83482599
10MP0009379_abnormal_foot_pigmentation2.62917221
11MP0003786_premature_aging2.60038797
12MP0008007_abnormal_cellular_replicative2.57197168
13MP0003718_maternal_effect2.48402829
14MP0008877_abnormal_DNA_methylation2.21155506
15MP0006292_abnormal_olfactory_placode2.04886184
16MP0008260_abnormal_autophagy2.03120337
17MP0003123_paternal_imprinting2.03092414
18MP0005410_abnormal_fertilization1.96195375
19MP0009785_altered_susceptibility_to1.90295082
20MP0001800_abnormal_humoral_immune1.88498958
21MP0002138_abnormal_hepatobiliary_system1.87784088
22MP0009333_abnormal_splenocyte_physiolog1.85175403
23MP0000685_abnormal_immune_system1.82018085
24MP0003136_yellow_coat_color1.78990132
25MP0002396_abnormal_hematopoietic_system1.78118239
26MP0002420_abnormal_adaptive_immunity1.75731705
27MP0001730_embryonic_growth_arrest1.74392231
28MP0001819_abnormal_immune_cell1.73282752
29MP0003646_muscle_fatigue1.71832464
30MP0002723_abnormal_immune_serum1.70461513
31MP0005000_abnormal_immune_tolerance1.66620017
32MP0000350_abnormal_cell_proliferation1.66039404
33MP0005025_abnormal_response_to1.64838139
34MP0002277_abnormal_respiratory_mucosa1.63276350
35MP0008789_abnormal_olfactory_epithelium1.62378446
36MP0002452_abnormal_antigen_presenting1.62304502
37MP0003315_abnormal_perineum_morphology1.61225370
38MP0002837_dystrophic_cardiac_calcinosis1.60680728
39MP0001529_abnormal_vocalization1.58682815
40MP0005075_abnormal_melanosome_morpholog1.56088257
41MP0005394_taste/olfaction_phenotype1.44923774
42MP0005499_abnormal_olfactory_system1.44923774
43MP0002163_abnormal_gland_morphology1.44838978
44MP0001790_abnormal_immune_system1.44533333
45MP0005387_immune_system_phenotype1.44533333
46MP0001873_stomach_inflammation1.43163538
47MP0000490_abnormal_crypts_of1.42807898
48MP0003806_abnormal_nucleotide_metabolis1.41378024
49MP0003186_abnormal_redox_activity1.39495419
50MP0000313_abnormal_cell_death1.35102652
51MP0004381_abnormal_hair_follicle1.32374181
52MP0001968_abnormal_touch/_nociception1.31688748
53MP0001986_abnormal_taste_sensitivity1.30523774
54MP0002419_abnormal_innate_immunity1.28998072
55MP0002210_abnormal_sex_determination1.28755904
56MP0003436_decreased_susceptibility_to1.27488312
57MP0002102_abnormal_ear_morphology1.27079258
58MP0001697_abnormal_embryo_size1.25875380
59MP0006036_abnormal_mitochondrial_physio1.25159789
60MP0002080_prenatal_lethality1.24164100
61MP0002638_abnormal_pupillary_reflex1.21127982
62MP0001727_abnormal_embryo_implantation1.20659213
63MP0000678_abnormal_parathyroid_gland1.19140350
64MP0005645_abnormal_hypothalamus_physiol1.18583660
65MP0002019_abnormal_tumor_incidence1.15881862
66MP0009278_abnormal_bone_marrow1.14594552
67MP0005380_embryogenesis_phenotype1.13669228
68MP0001672_abnormal_embryogenesis/_devel1.13669228
69MP0006035_abnormal_mitochondrial_morpho1.11326201
70MP0001984_abnormal_olfaction1.09323393
71MP0003724_increased_susceptibility_to1.08879970
72MP0000465_gastrointestinal_hemorrhage1.07903080
73MP0002085_abnormal_embryonic_tissue1.07691420
74MP0001145_abnormal_male_reproductive1.07690990
75MP0004133_heterotaxia1.05278985
76MP0002234_abnormal_pharynx_morphology1.05151777
77MP0005646_abnormal_pituitary_gland1.03607131
78MP0002876_abnormal_thyroid_physiology1.03136867
79MP0001929_abnormal_gametogenesis1.03006088
80MP0009764_decreased_sensitivity_to1.02070105
81MP0001542_abnormal_bone_strength1.02030978
82MP0006072_abnormal_retinal_apoptosis1.01258107
83MP0009697_abnormal_copulation1.00716748
84MP0000358_abnormal_cell_content/1.00572139
85MP0002405_respiratory_system_inflammati1.00278411
86MP0001845_abnormal_inflammatory_respons0.99923467
87MP0003567_abnormal_fetal_cardiomyocyte0.98915496
88MP0002938_white_spotting0.98881469
89MP0002160_abnormal_reproductive_system0.95735096
90MP0001188_hyperpigmentation0.95198584
91MP0002132_abnormal_respiratory_system0.94744984
92MP0000049_abnormal_middle_ear0.94240661
93MP0002751_abnormal_autonomic_nervous0.93067934
94MP0008872_abnormal_physiological_respon0.92681162
95MP0003698_abnormal_male_reproductive0.92154820
96MP0002736_abnormal_nociception_after0.92149793
97MP0008995_early_reproductive_senescence0.91716628
98MP0000703_abnormal_thymus_morphology0.91230935
99MP0001905_abnormal_dopamine_level0.90325460
100MP0003763_abnormal_thymus_physiology0.90115783
101MP0000653_abnormal_sex_gland0.89725106
102MP0000750_abnormal_muscle_regeneration0.89199159
103MP0003984_embryonic_growth_retardation0.87482841
104MP0002095_abnormal_skin_pigmentation0.87435104
105MP0003938_abnormal_ear_development0.86313766
106MP0002398_abnormal_bone_marrow0.86103271
107MP0002722_abnormal_immune_system0.84779480
108MP0005389_reproductive_system_phenotype0.84614927
109MP0008004_abnormal_stomach_pH0.84216313
110MP0008873_increased_physiological_sensi0.83845188
111MP0005174_abnormal_tail_pigmentation0.83340106
112MP0008469_abnormal_protein_level0.82549499
113MP0001853_heart_inflammation0.82156086
114MP0002088_abnormal_embryonic_growth/wei0.82074655
115MP0000015_abnormal_ear_pigmentation0.81305078
116MP0005379_endocrine/exocrine_gland_phen0.80255616
117MP0001764_abnormal_homeostasis0.80128582
118MP0000689_abnormal_spleen_morphology0.78501868
119MP0002084_abnormal_developmental_patter0.78365232
120MP0005166_decreased_susceptibility_to0.77260171
121MP0002429_abnormal_blood_cell0.75943066
122MP0003941_abnormal_skin_development0.75809387
123MP0000566_synostosis0.75800139
124MP0003119_abnormal_digestive_system0.74047090
125MP0004808_abnormal_hematopoietic_stem0.73845881
126MP0000372_irregular_coat_pigmentation0.73386650
127MP0006082_CNS_inflammation0.72890943
128MP0002111_abnormal_tail_morphology0.71310763
129MP0001919_abnormal_reproductive_system0.69129380
130MP0002148_abnormal_hypersensitivity_rea0.65568724
131MP0005395_other_phenotype0.65381994
132MP0001293_anophthalmia0.64730316
133MP0005671_abnormal_response_to0.64707370
134MP0000716_abnormal_immune_system0.63526392
135MP0005384_cellular_phenotype0.63516984
136MP0005408_hypopigmentation0.63099076
137MP0000858_altered_metastatic_potential0.62912013
138MP0003656_abnormal_erythrocyte_physiolo0.61867054
139MP0004142_abnormal_muscle_tone0.60673671
140MP0003937_abnormal_limbs/digits/tail_de0.60200810
141MP0010030_abnormal_orbit_morphology0.59187871
142MP0001119_abnormal_female_reproductive0.58233348
143MP0002086_abnormal_extraembryonic_tissu0.56481690
144MP0005397_hematopoietic_system_phenotyp0.56310171
145MP0001545_abnormal_hematopoietic_system0.56310171
146MP0010352_gastrointestinal_tract_polyps0.56137528

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)5.56494487
2Abnormality of cells of the erythroid lineage (HP:0012130)5.34206812
3Abnormal number of erythroid precursors (HP:0012131)5.02835102
4Cerebral hypomyelination (HP:0006808)4.38194977
5Birth length less than 3rd percentile (HP:0003561)4.36074814
6Macrocytic anemia (HP:0001972)3.91103248
7Breast hypoplasia (HP:0003187)3.87651449
8Pallor (HP:0000980)3.62859459
9Carpal bone hypoplasia (HP:0001498)3.58657687
10Mitochondrial inheritance (HP:0001427)3.46791634
11Acute necrotizing encephalopathy (HP:0006965)3.32049955
12Rough bone trabeculation (HP:0100670)3.31233445
13Aplasia/Hypoplasia of the sacrum (HP:0008517)3.31168743
14Increased hepatocellular lipid droplets (HP:0006565)3.26854615
15Hepatocellular necrosis (HP:0001404)3.23645966
16Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.18804008
17Reduced antithrombin III activity (HP:0001976)3.12705194
18Increased CSF lactate (HP:0002490)3.05690775
193-Methylglutaconic aciduria (HP:0003535)3.05457097
20Increased muscle lipid content (HP:0009058)2.95327482
21Type I transferrin isoform profile (HP:0003642)2.93703900
22Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.92507926
23Patellar aplasia (HP:0006443)2.90892987
24Exertional dyspnea (HP:0002875)2.90311699
25Abnormal mitochondria in muscle tissue (HP:0008316)2.87790283
26Aplasia/Hypoplasia of the patella (HP:0006498)2.87526905
27Trismus (HP:0000211)2.87342546
28Aplastic anemia (HP:0001915)2.87159158
29Cerebral edema (HP:0002181)2.86073935
30Chromosomal breakage induced by crosslinking agents (HP:0003221)2.85683690
31Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.84953785
32Decreased activity of mitochondrial respiratory chain (HP:0008972)2.84953785
33Chromsome breakage (HP:0040012)2.81946972
34Renal Fanconi syndrome (HP:0001994)2.80368558
35Lipid accumulation in hepatocytes (HP:0006561)2.77318155
36Secondary amenorrhea (HP:0000869)2.76441519
37Panhypogammaglobulinemia (HP:0003139)2.75436849
38Increased serum lactate (HP:0002151)2.75364875
39Oral leukoplakia (HP:0002745)2.73041403
40Premature ovarian failure (HP:0008209)2.72958828
41Horseshoe kidney (HP:0000085)2.67441890
42Abnormal trabecular bone morphology (HP:0100671)2.66885404
43Hepatic necrosis (HP:0002605)2.65364777
44Abnormality of the anterior horn cell (HP:0006802)2.61255977
45Degeneration of anterior horn cells (HP:0002398)2.61255977
46Meckel diverticulum (HP:0002245)2.60182510
47Stomatitis (HP:0010280)2.57826461
48Abnormality of the preputium (HP:0100587)2.57305111
49Abnormality of the ileum (HP:0001549)2.53584315
50Absent radius (HP:0003974)2.50774667
51Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.50594856
52Increased IgM level (HP:0003496)2.48246825
53Absent thumb (HP:0009777)2.46955532
54Premature graying of hair (HP:0002216)2.45860756
55Duplicated collecting system (HP:0000081)2.44749804
56Molar tooth sign on MRI (HP:0002419)2.43432246
57Abnormality of midbrain morphology (HP:0002418)2.43432246
58Absent rod-and cone-mediated responses on ERG (HP:0007688)2.42825347
59Optic disc pallor (HP:0000543)2.42004250
60Abnormality of the prostate (HP:0008775)2.40807603
61Obstructive lung disease (HP:0006536)2.40457528
62Chronic obstructive pulmonary disease (HP:0006510)2.40457528
63Acute encephalopathy (HP:0006846)2.39831534
64Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.39256248
65CNS hypomyelination (HP:0003429)2.37255247
66Abnormality of B cell number (HP:0010975)2.37049972
67Microretrognathia (HP:0000308)2.36124997
68Abnormality of T cell physiology (HP:0011840)2.35596069
69Microvesicular hepatic steatosis (HP:0001414)2.35165733
70Progressive macrocephaly (HP:0004481)2.34959769
71Abnormality of the umbilical cord (HP:0010881)2.31820852
72Delusions (HP:0000746)2.30562460
73Triphalangeal thumb (HP:0001199)2.29607407
74Respiratory difficulties (HP:0002880)2.29417300
75Absent forearm bone (HP:0003953)2.28804483
76Aplasia involving forearm bones (HP:0009822)2.28804483
77IgG deficiency (HP:0004315)2.28235197
78Irregular epiphyses (HP:0010582)2.28040749
79Ureteral duplication (HP:0000073)2.26249294
80Prostate neoplasm (HP:0100787)2.24597451
81Elevated erythrocyte sedimentation rate (HP:0003565)2.24309119
82Bone marrow hypocellularity (HP:0005528)2.23849947
83Hypoplasia of the uterus (HP:0000013)2.23644386
84Abnormal delayed hypersensitivity skin test (HP:0002963)2.20279488
85Exercise intolerance (HP:0003546)2.19231847
86Multiple enchondromatosis (HP:0005701)2.18896988
87Aplasia/Hypoplasia involving the musculature (HP:0001460)2.17304099
88Abnormal umbilical cord blood vessels (HP:0011403)2.17246277
89Single umbilical artery (HP:0001195)2.17246277
90Abnormality of the fetal cardiovascular system (HP:0010948)2.17246277
91Lethargy (HP:0001254)2.14713514
92Leukodystrophy (HP:0002415)2.14149877
93Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.13108788
94Abnormal protein N-linked glycosylation (HP:0012347)2.13108788
95Abnormal protein glycosylation (HP:0012346)2.13108788
96Abnormal glycosylation (HP:0012345)2.13108788
9711 pairs of ribs (HP:0000878)2.11722131
98Dicarboxylic aciduria (HP:0003215)2.11485723
99Abnormality of dicarboxylic acid metabolism (HP:0010995)2.11485723
100Pancytopenia (HP:0001876)2.10319965
101Methylmalonic aciduria (HP:0012120)2.10037470
102Aplasia/hypoplasia of the uterus (HP:0008684)2.09300133
103B lymphocytopenia (HP:0010976)2.08674601
104Eosinophilia (HP:0001880)2.08327759
105Abnormality of T cells (HP:0002843)2.08010837
106Granulocytopenia (HP:0001913)2.07873047
107Cleft eyelid (HP:0000625)2.07816316
108Hypoplasia of the pons (HP:0012110)2.07438124
109Respiratory failure (HP:0002878)2.06911637
110CNS demyelination (HP:0007305)2.06516036
111Abnormality of the renal collecting system (HP:0004742)2.05133826
112Glossoptosis (HP:0000162)2.04683547
113Increased intramyocellular lipid droplets (HP:0012240)2.03821412
114Pancreatic cysts (HP:0001737)2.03791058
115Agammaglobulinemia (HP:0004432)2.03785609
116Abnormality of glycolysis (HP:0004366)2.00728443
117Increased serum pyruvate (HP:0003542)2.00728443
118Emotional lability (HP:0000712)1.99815052
119Aplasia/Hypoplasia of the uvula (HP:0010293)1.98485903
120Lactic acidosis (HP:0003128)1.98334529
121Progressive muscle weakness (HP:0003323)1.98047474
122Hypoplasia of the radius (HP:0002984)1.97550435
123Mediastinal lymphadenopathy (HP:0100721)1.96820911
124Hypomagnesemia (HP:0002917)1.96566219
125Abnormality of chromosome stability (HP:0003220)1.96286926
126Impulsivity (HP:0100710)1.94855197
127Poor head control (HP:0002421)1.93777424
128Recurrent fungal infections (HP:0002841)1.93677959
129Severe combined immunodeficiency (HP:0004430)1.93284712
130Sclerocornea (HP:0000647)1.93037205
131Concave nail (HP:0001598)1.91798408
132Muscle fiber atrophy (HP:0100295)1.91385299
133Recurrent bacterial skin infections (HP:0005406)1.90045549
134Abnormality of the columella (HP:0009929)1.89944477
135Abnormality of the pons (HP:0007361)1.88593564
136Abnormality of the heme biosynthetic pathway (HP:0010472)1.88386545
137Progressive microcephaly (HP:0000253)1.88106089
138Thrombocytosis (HP:0001894)1.86532061
139Hypoplasia of the capital femoral epiphysis (HP:0003090)1.86043201
140Generalized aminoaciduria (HP:0002909)1.85284165
141Unsteady gait (HP:0002317)1.85176210
142Hyperglycinemia (HP:0002154)1.84273899
143Decreased electroretinogram (ERG) amplitude (HP:0000654)1.82954810
144Abnormal rod and cone electroretinograms (HP:0008323)1.82770366
145Pancreatic fibrosis (HP:0100732)1.80849719
146Ragged-red muscle fibers (HP:0003200)1.79390515
147Tetany (HP:0001281)1.79280104
148Abnormality of male internal genitalia (HP:0000022)1.76318267
149Abnormality of magnesium homeostasis (HP:0004921)1.73824380
150Neutropenia (HP:0001875)1.73797398
151Recurrent cutaneous fungal infections (HP:0011370)1.72911210
152Chronic mucocutaneous candidiasis (HP:0002728)1.72911210
153Recurrent viral infections (HP:0004429)1.72887136
154Colon cancer (HP:0003003)1.72552893
155Testicular atrophy (HP:0000029)1.71593445

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB15.20975464
2VRK25.16227812
3STK163.93216229
4WEE13.91475123
5EIF2AK13.87522730
6NME23.77990781
7PINK13.19394561
8TLK13.13376066
9SRPK12.76726750
10NME12.64196555
11BCKDK2.25554643
12VRK12.20315233
13CDC72.18373671
14MARK32.07105113
15PLK42.01113616
16PIM21.97149992
17EIF2AK31.95351178
18TESK21.91974760
19TSSK61.89996170
20BRSK21.86636309
21NUAK11.86381032
22ZAK1.84243183
23PLK11.77438269
24MKNK21.71427185
25MKNK11.71366063
26DYRK31.68667485
27TTK1.64605687
28PNCK1.57789319
29BMPR1B1.57167422
30CSNK1A1L1.51391042
31AURKA1.50134286
32NEK21.49341455
33PLK31.42008690
34AURKB1.35367649
35CDK71.31920671
36MAP4K21.30006589
37PBK1.28079822
38EPHA21.27614240
39CSNK1G21.22341607
40CHEK21.16713519
41PRKD31.16088962
42BRSK11.15785724
43IRAK41.15270230
44TAF11.11929393
45FES1.11394341
46ACVR1B1.09084547
47BRAF1.07561173
48DYRK21.03193171
49DAPK11.02469367
50IRAK31.01349096
51MAP3K110.99615683
52SMG10.97908547
53ARAF0.95497852
54SYK0.93123921
55RPS6KA40.93085891
56MST40.92358899
57RPS6KB20.91878374
58PASK0.91270827
59ATR0.90975265
60EIF2AK20.89771018
61IKBKE0.86868327
62PAK10.86227699
63CCNB10.84238880
64BLK0.84164289
65MAP2K70.83717709
66CSNK2A10.82319671
67TNK20.81333385
68CSNK2A20.79332082
69CDK190.78620798
70PRKCI0.78218760
71TRIM280.74251521
72MAP3K80.72034755
73ABL20.71905691
74CHEK10.71830326
75RPS6KA50.71125540
76PDK20.71114889
77CDK40.68536037
78TBK10.67695845
79CDK80.65272677
80WNK30.64278885
81GRK50.64276922
82GRK10.62410158
83LRRK20.62375244
84CLK10.61908340
85PRKCQ0.61907934
86TYK20.59124783
87PIM10.57047045
88TESK10.56457105
89STK40.56381471
90FRK0.55641118
91ZAP700.54510228
92CDK20.54075772
93MAPKAPK50.52642909
94SCYL20.52127639
95KDR0.51703385
96LATS20.47188994
97AKT30.47049785
98ADRBK20.47003548
99MAPK130.45938159
100NEK10.44682996
101ATM0.44602369
102MAP2K20.43445638
103ITK0.43179798
104LIMK10.42631997
105STK240.41679649
106CAMKK20.40771877
107NLK0.39155090
108MAPK110.39144087
109CSNK1G30.38693036
110MAP4K10.38314648
111ILK0.36832979
112IKBKB0.36730262
113CDK10.36358307
114PAK40.36141190
115CSNK1E0.35983329
116IRAK20.33413623
117CDK90.32984063
118TAOK30.32191752
119INSRR0.32106201
120MATK0.31971198
121STK38L0.31597429
122TEC0.31464214
123TXK0.30550357
124CDK30.29146103
125DAPK30.28663655
126CSNK1G10.28327056
127BMPR20.28236381
128LYN0.26705302
129GRK60.26263376
130STK100.24866190
131MAP2K60.23551891
132MAPKAPK30.22946717
133GRK70.22850389
134MAPKAPK20.22218390
135CDK11A0.21483180
136KIT0.21454305
137BTK0.19178854

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.02429525
2Proteasome_Homo sapiens_hsa030504.48980782
3RNA polymerase_Homo sapiens_hsa030204.29161521
4DNA replication_Homo sapiens_hsa030303.84730588
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.62193368
6Mismatch repair_Homo sapiens_hsa034303.36338742
7Spliceosome_Homo sapiens_hsa030403.00892698
8Homologous recombination_Homo sapiens_hsa034402.88321246
9Pyrimidine metabolism_Homo sapiens_hsa002402.78634235
10RNA transport_Homo sapiens_hsa030132.64528642
11Nucleotide excision repair_Homo sapiens_hsa034202.59193176
12Base excision repair_Homo sapiens_hsa034102.41017001
13Protein export_Homo sapiens_hsa030602.36724521
14Basal transcription factors_Homo sapiens_hsa030222.19892331
15Oxidative phosphorylation_Homo sapiens_hsa001902.13562884
16Fanconi anemia pathway_Homo sapiens_hsa034602.02049939
17Parkinsons disease_Homo sapiens_hsa050121.90541996
18Cell cycle_Homo sapiens_hsa041101.85749505
19Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.78336237
20One carbon pool by folate_Homo sapiens_hsa006701.77304803
21Huntingtons disease_Homo sapiens_hsa050161.66418970
22Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.66368997
23Vitamin B6 metabolism_Homo sapiens_hsa007501.66076640
24Non-homologous end-joining_Homo sapiens_hsa034501.65969638
25Purine metabolism_Homo sapiens_hsa002301.59457311
26RNA degradation_Homo sapiens_hsa030181.50149881
27Folate biosynthesis_Homo sapiens_hsa007901.28038062
28p53 signaling pathway_Homo sapiens_hsa041151.26526676
29Alzheimers disease_Homo sapiens_hsa050101.18061747
30Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.16982169
31Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.15547252
32Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.12462849
33mRNA surveillance pathway_Homo sapiens_hsa030151.11599810
34Epstein-Barr virus infection_Homo sapiens_hsa051691.11444108
35Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.04918692
36Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.04741765
37Sulfur relay system_Homo sapiens_hsa041221.03585626
38Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.95781966
39Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.89333801
40Sulfur metabolism_Homo sapiens_hsa009200.79158802
41Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.73084013
42Leishmaniasis_Homo sapiens_hsa051400.71339377
43Drug metabolism - other enzymes_Homo sapiens_hsa009830.69475556
44Viral myocarditis_Homo sapiens_hsa054160.67821641
45Pentose phosphate pathway_Homo sapiens_hsa000300.66765929
46Peroxisome_Homo sapiens_hsa041460.65032915
47Regulation of autophagy_Homo sapiens_hsa041400.64975281
48Arachidonic acid metabolism_Homo sapiens_hsa005900.63901732
49Phototransduction_Homo sapiens_hsa047440.62095298
50Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.61191284
51Glutathione metabolism_Homo sapiens_hsa004800.59907616
52Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.59111711
53Cysteine and methionine metabolism_Homo sapiens_hsa002700.58806120
54Staphylococcus aureus infection_Homo sapiens_hsa051500.57865260
55Systemic lupus erythematosus_Homo sapiens_hsa053220.57096575
56Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.55416171
57Herpes simplex infection_Homo sapiens_hsa051680.54443096
58Metabolic pathways_Homo sapiens_hsa011000.54246750
59Olfactory transduction_Homo sapiens_hsa047400.53509501
60Sphingolipid metabolism_Homo sapiens_hsa006000.52921589
61Pyruvate metabolism_Homo sapiens_hsa006200.51712212
62Asthma_Homo sapiens_hsa053100.51692541
63Antigen processing and presentation_Homo sapiens_hsa046120.50728792
64Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.49438797
65Oocyte meiosis_Homo sapiens_hsa041140.46832873
66Primary immunodeficiency_Homo sapiens_hsa053400.46679226
67Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.45635230
68Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.45254446
69Other glycan degradation_Homo sapiens_hsa005110.45002690
70Propanoate metabolism_Homo sapiens_hsa006400.43527765
71Cyanoamino acid metabolism_Homo sapiens_hsa004600.41905061
72Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.41527872
73Tuberculosis_Homo sapiens_hsa051520.38270194
74Nitrogen metabolism_Homo sapiens_hsa009100.38206466
75Viral carcinogenesis_Homo sapiens_hsa052030.38005887
76Linoleic acid metabolism_Homo sapiens_hsa005910.36737970
77Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.36580858
78SNARE interactions in vesicular transport_Homo sapiens_hsa041300.36350044
79Intestinal immune network for IgA production_Homo sapiens_hsa046720.35572604
80Allograft rejection_Homo sapiens_hsa053300.34368512
81N-Glycan biosynthesis_Homo sapiens_hsa005100.33765978
82Steroid biosynthesis_Homo sapiens_hsa001000.33683757
83Fructose and mannose metabolism_Homo sapiens_hsa000510.33356013
84Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.32607593
85Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.32472649
86Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.32265566
87Arginine and proline metabolism_Homo sapiens_hsa003300.29369969
88Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.28571743
89Legionellosis_Homo sapiens_hsa051340.26527430
90HTLV-I infection_Homo sapiens_hsa051660.25961040
91Cardiac muscle contraction_Homo sapiens_hsa042600.25836455
92Chemical carcinogenesis_Homo sapiens_hsa052040.25410380
93Hematopoietic cell lineage_Homo sapiens_hsa046400.25312761
94Vibrio cholerae infection_Homo sapiens_hsa051100.24513151
95Butanoate metabolism_Homo sapiens_hsa006500.23438177
96Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.22765217
97Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.20769228
98Biosynthesis of amino acids_Homo sapiens_hsa012300.20141108
99Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.18615113
100Ether lipid metabolism_Homo sapiens_hsa005650.18509448
101Fatty acid elongation_Homo sapiens_hsa000620.18281725
102NF-kappa B signaling pathway_Homo sapiens_hsa040640.18040304
103Apoptosis_Homo sapiens_hsa042100.16629769
104Collecting duct acid secretion_Homo sapiens_hsa049660.15828295
105Alcoholism_Homo sapiens_hsa050340.15315622
106Measles_Homo sapiens_hsa051620.13645893
107Thyroid cancer_Homo sapiens_hsa052160.13638762
108Maturity onset diabetes of the young_Homo sapiens_hsa049500.13442504
109NOD-like receptor signaling pathway_Homo sapiens_hsa046210.12589858
110Autoimmune thyroid disease_Homo sapiens_hsa053200.12023117
111Shigellosis_Homo sapiens_hsa051310.11950257
112Rheumatoid arthritis_Homo sapiens_hsa053230.10590157
113Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.10482482
114alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.09709968
115Type I diabetes mellitus_Homo sapiens_hsa049400.09390027
116Galactose metabolism_Homo sapiens_hsa000520.06391796
117Transcriptional misregulation in cancer_Homo sapiens_hsa052020.05163426
118Graft-versus-host disease_Homo sapiens_hsa053320.04713066
119Selenocompound metabolism_Homo sapiens_hsa004500.04474458
120Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.03869729
121RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.03846133
122Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.03253231
123Phagosome_Homo sapiens_hsa041450.01801026

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