Rank | Gene Set | Z-score |
---|---|---|
1 | maturation of SSU-rRNA (GO:0030490) | 5.60166594 |
2 | ribosomal small subunit biogenesis (GO:0042274) | 5.48747852 |
3 | ribosomal small subunit assembly (GO:0000028) | 5.47045324 |
4 | viral transcription (GO:0019083) | 5.32422931 |
5 | translational termination (GO:0006415) | 5.21166920 |
6 | DNA deamination (GO:0045006) | 5.00663713 |
7 | ribosomal large subunit biogenesis (GO:0042273) | 4.89050317 |
8 | proteasome assembly (GO:0043248) | 4.79864630 |
9 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.72546534 |
10 | cotranslational protein targeting to membrane (GO:0006613) | 4.65975438 |
11 | protein targeting to ER (GO:0045047) | 4.62607635 |
12 | ribonucleoprotein complex biogenesis (GO:0022613) | 4.56735727 |
13 | translational elongation (GO:0006414) | 4.56249002 |
14 | translational initiation (GO:0006413) | 4.56067815 |
15 | termination of RNA polymerase III transcription (GO:0006386) | 4.48833446 |
16 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 4.48833446 |
17 | protein localization to endoplasmic reticulum (GO:0070972) | 4.40166399 |
18 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.39953568 |
19 | formation of translation preinitiation complex (GO:0001731) | 4.38117466 |
20 | protein complex biogenesis (GO:0070271) | 4.27537053 |
21 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.19018626 |
22 | NADH dehydrogenase complex assembly (GO:0010257) | 4.19018626 |
23 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.19018626 |
24 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.16910524 |
25 | ribosome biogenesis (GO:0042254) | 4.16785317 |
26 | cellular protein complex disassembly (GO:0043624) | 4.13458015 |
27 | rRNA processing (GO:0006364) | 4.11399888 |
28 | DNA replication checkpoint (GO:0000076) | 4.10076295 |
29 | 7-methylguanosine mRNA capping (GO:0006370) | 4.07876829 |
30 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.07843379 |
31 | viral life cycle (GO:0019058) | 4.07394147 |
32 | translation (GO:0006412) | 4.04011830 |
33 | ATP synthesis coupled proton transport (GO:0015986) | 4.00522893 |
34 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.00522893 |
35 | RNA capping (GO:0036260) | 3.99843770 |
36 | 7-methylguanosine RNA capping (GO:0009452) | 3.99843770 |
37 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.98269143 |
38 | rRNA metabolic process (GO:0016072) | 3.97185271 |
39 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.95679504 |
40 | spliceosomal snRNP assembly (GO:0000387) | 3.94603899 |
41 | chaperone-mediated protein transport (GO:0072321) | 3.92143933 |
42 | purine deoxyribonucleotide catabolic process (GO:0009155) | 3.92115215 |
43 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.87118274 |
44 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.85452198 |
45 | rRNA modification (GO:0000154) | 3.81719901 |
46 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.81091455 |
47 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.78541832 |
48 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.77495497 |
49 | ribosome assembly (GO:0042255) | 3.77492389 |
50 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.77473766 |
51 | purine nucleobase biosynthetic process (GO:0009113) | 3.77237793 |
52 | cellular component biogenesis (GO:0044085) | 3.77207380 |
53 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.76157072 |
54 | base-excision repair, AP site formation (GO:0006285) | 3.75752710 |
55 | DNA strand elongation (GO:0022616) | 3.74861042 |
56 | negative regulation of ligase activity (GO:0051352) | 3.71188549 |
57 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.71188549 |
58 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.71149569 |
59 | nucleobase biosynthetic process (GO:0046112) | 3.70820440 |
60 | pseudouridine synthesis (GO:0001522) | 3.69579853 |
61 | mitotic metaphase plate congression (GO:0007080) | 3.69301771 |
62 | cullin deneddylation (GO:0010388) | 3.69278423 |
63 | termination of RNA polymerase I transcription (GO:0006363) | 3.68719325 |
64 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.68391003 |
65 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 3.67913859 |
66 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.65391235 |
67 | transcription from RNA polymerase I promoter (GO:0006360) | 3.64399473 |
68 | deoxyribonucleotide catabolic process (GO:0009264) | 3.63678076 |
69 | protein complex disassembly (GO:0043241) | 3.61988451 |
70 | spliceosomal complex assembly (GO:0000245) | 3.61779955 |
71 | DNA replication initiation (GO:0006270) | 3.61771342 |
72 | protein deneddylation (GO:0000338) | 3.55982584 |
73 | respiratory chain complex IV assembly (GO:0008535) | 3.53331891 |
74 | transcription-coupled nucleotide-excision repair (GO:0006283) | 3.52568417 |
75 | macromolecular complex disassembly (GO:0032984) | 3.48838430 |
76 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.48107011 |
77 | rRNA methylation (GO:0031167) | 3.47935162 |
78 | cytochrome complex assembly (GO:0017004) | 3.47218539 |
79 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.45887718 |
80 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.45887718 |
81 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.45887718 |
82 | telomere maintenance via recombination (GO:0000722) | 3.45519901 |
83 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.45445236 |
84 | deoxyribose phosphate catabolic process (GO:0046386) | 3.44115556 |
85 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.44001925 |
86 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.44001925 |
87 | CENP-A containing nucleosome assembly (GO:0034080) | 3.42703231 |
88 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.41897330 |
89 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.41897330 |
90 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.38724314 |
91 | protein targeting to mitochondrion (GO:0006626) | 3.35924646 |
92 | chromatin remodeling at centromere (GO:0031055) | 3.35171201 |
93 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.34329836 |
94 | respiratory electron transport chain (GO:0022904) | 3.32931217 |
95 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.29802578 |
96 | electron transport chain (GO:0022900) | 3.29155125 |
97 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.27577510 |
98 | maturation of 5.8S rRNA (GO:0000460) | 3.27385000 |
99 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.23289920 |
100 | peptidyl-histidine modification (GO:0018202) | 3.21787002 |
101 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.21117377 |
102 | positive regulation of ligase activity (GO:0051351) | 3.20321638 |
103 | mitotic recombination (GO:0006312) | 3.19423324 |
104 | viral mRNA export from host cell nucleus (GO:0046784) | 3.18199785 |
105 | kinetochore assembly (GO:0051382) | 3.16438655 |
106 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.16403203 |
107 | metaphase plate congression (GO:0051310) | 3.15824157 |
108 | transcription initiation from RNA polymerase I promoter (GO:0006361) | 3.15300406 |
109 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.15132100 |
110 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 3.15074727 |
111 | ncRNA processing (GO:0034470) | 3.14232803 |
112 | establishment of integrated proviral latency (GO:0075713) | 3.13794990 |
113 | transcription elongation from RNA polymerase II promoter (GO:0006368) | 3.12875271 |
114 | establishment of protein localization to mitochondrion (GO:0072655) | 3.12633183 |
115 | regulation of mitochondrial translation (GO:0070129) | 3.12148373 |
116 | L-methionine salvage (GO:0071267) | 3.11008408 |
117 | L-methionine biosynthetic process (GO:0071265) | 3.11008408 |
118 | amino acid salvage (GO:0043102) | 3.11008408 |
119 | telomere maintenance via telomere lengthening (GO:0010833) | 3.10805027 |
120 | purine deoxyribonucleotide metabolic process (GO:0009151) | 3.10579382 |
121 | negative regulation of B cell apoptotic process (GO:0002903) | 3.10310530 |
122 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.10258335 |
123 | GTP biosynthetic process (GO:0006183) | 3.09703824 |
124 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.09043270 |
125 | mRNA catabolic process (GO:0006402) | 3.07370479 |
126 | positive regulation of viral transcription (GO:0050434) | 3.06948344 |
127 | DNA damage response, detection of DNA damage (GO:0042769) | 3.06169514 |
128 | ncRNA metabolic process (GO:0034660) | 3.06114880 |
129 | protein neddylation (GO:0045116) | 3.05671218 |
130 | tRNA processing (GO:0008033) | 3.04284418 |
131 | iron-sulfur cluster assembly (GO:0016226) | 3.01884235 |
132 | metallo-sulfur cluster assembly (GO:0031163) | 3.01884235 |
133 | 2-deoxyribonucleotide metabolic process (GO:0009394) | 2.97421901 |
134 | protein localization to mitochondrion (GO:0070585) | 2.94033406 |
135 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.92774459 |
136 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.86284511 |
137 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.86284511 |
138 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.83440123 |
139 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.81228078 |
140 | replication fork processing (GO:0031297) | 2.78745575 |
141 | tRNA modification (GO:0006400) | 2.78709683 |
142 | deoxyribose phosphate metabolic process (GO:0019692) | 2.77614809 |
143 | DNA double-strand break processing (GO:0000729) | 2.74976044 |
144 | UTP biosynthetic process (GO:0006228) | 2.73505885 |
145 | RNA phosphodiester bond hydrolysis, endonucleolytic (GO:0090502) | 2.72679225 |
146 | mitochondrial RNA metabolic process (GO:0000959) | 2.66270817 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 5.26964258 |
2 | * MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.53141790 |
3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.35826490 |
4 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.95715641 |
5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.91320051 |
6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.88005561 |
7 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.76226265 |
8 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.75725445 |
9 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.34268595 |
10 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.25778817 |
11 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 3.23313988 |
12 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.22104551 |
13 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.21103111 |
14 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 3.19336721 |
15 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 3.00974345 |
16 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.96123286 |
17 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.89642737 |
18 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.75786539 |
19 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.75432761 |
20 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.69407809 |
21 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.60536194 |
22 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.60207799 |
23 | * VDR_23849224_ChIP-Seq_CD4+_Human | 2.58351753 |
24 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.52975029 |
25 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.47112895 |
26 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.46094059 |
27 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.44750407 |
28 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 2.25211483 |
29 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.23885138 |
30 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.22991812 |
31 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.19214918 |
32 | * FOXP3_21729870_ChIP-Seq_TREG_Human | 2.18826338 |
33 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.17242968 |
34 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.14716025 |
35 | * GABP_19822575_ChIP-Seq_HepG2_Human | 2.13114561 |
36 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.12731105 |
37 | * TTF2_22483619_ChIP-Seq_HELA_Human | 2.09989742 |
38 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.04824997 |
39 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.96261115 |
40 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.84613565 |
41 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.84458093 |
42 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.83786638 |
43 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.80861471 |
44 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.77096019 |
45 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.74447675 |
46 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.74248816 |
47 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.71049434 |
48 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.65131397 |
49 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.60139479 |
50 | * TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.59026233 |
51 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.51535506 |
52 | * FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.50274467 |
53 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.49276752 |
54 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.44829190 |
55 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.41888104 |
56 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.40692402 |
57 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.40009030 |
58 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.39355272 |
59 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.38095086 |
60 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.37038818 |
61 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.36187613 |
62 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.35885882 |
63 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.35297839 |
64 | * CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.34672800 |
65 | * SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.32548516 |
66 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.32396141 |
67 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.31845981 |
68 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.31480821 |
69 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.30778879 |
70 | * ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.30039670 |
71 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.29831517 |
72 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.28786006 |
73 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.28241076 |
74 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.26206422 |
75 | * POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.21930733 |
76 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.21331422 |
77 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.18849595 |
78 | * ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.18130770 |
79 | MAF_26560356_Chip-Seq_TH2_Human | 1.16794658 |
80 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.15234075 |
81 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.13802331 |
82 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.12584616 |
83 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.12533538 |
84 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.10781424 |
85 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.09673454 |
86 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.08773942 |
87 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.07336414 |
88 | * CTCF_26484167_Chip-Seq_Bcells_Mouse | 1.06077894 |
89 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.06028450 |
90 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.04730782 |
91 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.04416991 |
92 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.02527034 |
93 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.01518387 |
94 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.01045691 |
95 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.00696695 |
96 | P68_20966046_ChIP-Seq_HELA_Human | 1.00645009 |
97 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.00558550 |
98 | ERA_21632823_ChIP-Seq_H3396_Human | 0.99579700 |
99 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.98572489 |
100 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.98560905 |
101 | PHF8_20622854_ChIP-Seq_HELA_Human | 0.98301675 |
102 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.98111424 |
103 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.97545475 |
104 | MYB_26560356_Chip-Seq_TH2_Human | 0.97321642 |
105 | ZNF274_21170338_ChIP-Seq_K562_Hela | 0.94286598 |
106 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.94013863 |
107 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.93568112 |
108 | MYC_22102868_ChIP-Seq_BL_Human | 0.91337804 |
109 | P300_27268052_Chip-Seq_Bcells_Human | 0.91188674 |
110 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.91150097 |
111 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.90112197 |
112 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.89233091 |
113 | * HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.88954585 |
114 | * SPI1_23547873_ChIP-Seq_NB4_Human | 0.87764611 |
115 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 0.87676339 |
116 | * KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.87252154 |
117 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.84649032 |
118 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.84094717 |
119 | * FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.84058186 |
120 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.83117569 |
121 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.79021222 |
122 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.78864948 |
123 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.78640009 |
124 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.75682657 |
125 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.75671842 |
126 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.74190866 |
127 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.73021896 |
128 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.73009412 |
129 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.71381951 |
130 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.69585225 |
131 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.69508291 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 6.39679813 |
2 | MP0004957_abnormal_blastocyst_morpholog | 4.50559154 |
3 | MP0003111_abnormal_nucleus_morphology | 4.28220443 |
4 | MP0010094_abnormal_chromosome_stability | 3.80972162 |
5 | MP0003077_abnormal_cell_cycle | 3.61364752 |
6 | MP0008058_abnormal_DNA_repair | 3.42945335 |
7 | MP0008057_abnormal_DNA_replication | 3.34162696 |
8 | MP0008932_abnormal_embryonic_tissue | 3.26398389 |
9 | MP0001835_abnormal_antigen_presentation | 2.83482599 |
10 | MP0009379_abnormal_foot_pigmentation | 2.62917221 |
11 | MP0003786_premature_aging | 2.60038797 |
12 | MP0008007_abnormal_cellular_replicative | 2.57197168 |
13 | MP0003718_maternal_effect | 2.48402829 |
14 | MP0008877_abnormal_DNA_methylation | 2.21155506 |
15 | MP0006292_abnormal_olfactory_placode | 2.04886184 |
16 | MP0008260_abnormal_autophagy | 2.03120337 |
17 | MP0003123_paternal_imprinting | 2.03092414 |
18 | MP0005410_abnormal_fertilization | 1.96195375 |
19 | MP0009785_altered_susceptibility_to | 1.90295082 |
20 | MP0001800_abnormal_humoral_immune | 1.88498958 |
21 | MP0002138_abnormal_hepatobiliary_system | 1.87784088 |
22 | MP0009333_abnormal_splenocyte_physiolog | 1.85175403 |
23 | MP0000685_abnormal_immune_system | 1.82018085 |
24 | MP0003136_yellow_coat_color | 1.78990132 |
25 | MP0002396_abnormal_hematopoietic_system | 1.78118239 |
26 | MP0002420_abnormal_adaptive_immunity | 1.75731705 |
27 | MP0001730_embryonic_growth_arrest | 1.74392231 |
28 | MP0001819_abnormal_immune_cell | 1.73282752 |
29 | MP0003646_muscle_fatigue | 1.71832464 |
30 | MP0002723_abnormal_immune_serum | 1.70461513 |
31 | MP0005000_abnormal_immune_tolerance | 1.66620017 |
32 | MP0000350_abnormal_cell_proliferation | 1.66039404 |
33 | MP0005025_abnormal_response_to | 1.64838139 |
34 | MP0002277_abnormal_respiratory_mucosa | 1.63276350 |
35 | MP0008789_abnormal_olfactory_epithelium | 1.62378446 |
36 | MP0002452_abnormal_antigen_presenting | 1.62304502 |
37 | MP0003315_abnormal_perineum_morphology | 1.61225370 |
38 | MP0002837_dystrophic_cardiac_calcinosis | 1.60680728 |
39 | MP0001529_abnormal_vocalization | 1.58682815 |
40 | MP0005075_abnormal_melanosome_morpholog | 1.56088257 |
41 | MP0005394_taste/olfaction_phenotype | 1.44923774 |
42 | MP0005499_abnormal_olfactory_system | 1.44923774 |
43 | MP0002163_abnormal_gland_morphology | 1.44838978 |
44 | MP0001790_abnormal_immune_system | 1.44533333 |
45 | MP0005387_immune_system_phenotype | 1.44533333 |
46 | MP0001873_stomach_inflammation | 1.43163538 |
47 | MP0000490_abnormal_crypts_of | 1.42807898 |
48 | MP0003806_abnormal_nucleotide_metabolis | 1.41378024 |
49 | MP0003186_abnormal_redox_activity | 1.39495419 |
50 | MP0000313_abnormal_cell_death | 1.35102652 |
51 | MP0004381_abnormal_hair_follicle | 1.32374181 |
52 | MP0001968_abnormal_touch/_nociception | 1.31688748 |
53 | MP0001986_abnormal_taste_sensitivity | 1.30523774 |
54 | MP0002419_abnormal_innate_immunity | 1.28998072 |
55 | MP0002210_abnormal_sex_determination | 1.28755904 |
56 | MP0003436_decreased_susceptibility_to | 1.27488312 |
57 | MP0002102_abnormal_ear_morphology | 1.27079258 |
58 | MP0001697_abnormal_embryo_size | 1.25875380 |
59 | MP0006036_abnormal_mitochondrial_physio | 1.25159789 |
60 | MP0002080_prenatal_lethality | 1.24164100 |
61 | MP0002638_abnormal_pupillary_reflex | 1.21127982 |
62 | MP0001727_abnormal_embryo_implantation | 1.20659213 |
63 | MP0000678_abnormal_parathyroid_gland | 1.19140350 |
64 | MP0005645_abnormal_hypothalamus_physiol | 1.18583660 |
65 | MP0002019_abnormal_tumor_incidence | 1.15881862 |
66 | MP0009278_abnormal_bone_marrow | 1.14594552 |
67 | MP0005380_embryogenesis_phenotype | 1.13669228 |
68 | MP0001672_abnormal_embryogenesis/_devel | 1.13669228 |
69 | MP0006035_abnormal_mitochondrial_morpho | 1.11326201 |
70 | MP0001984_abnormal_olfaction | 1.09323393 |
71 | MP0003724_increased_susceptibility_to | 1.08879970 |
72 | MP0000465_gastrointestinal_hemorrhage | 1.07903080 |
73 | MP0002085_abnormal_embryonic_tissue | 1.07691420 |
74 | MP0001145_abnormal_male_reproductive | 1.07690990 |
75 | MP0004133_heterotaxia | 1.05278985 |
76 | MP0002234_abnormal_pharynx_morphology | 1.05151777 |
77 | MP0005646_abnormal_pituitary_gland | 1.03607131 |
78 | MP0002876_abnormal_thyroid_physiology | 1.03136867 |
79 | MP0001929_abnormal_gametogenesis | 1.03006088 |
80 | MP0009764_decreased_sensitivity_to | 1.02070105 |
81 | MP0001542_abnormal_bone_strength | 1.02030978 |
82 | MP0006072_abnormal_retinal_apoptosis | 1.01258107 |
83 | MP0009697_abnormal_copulation | 1.00716748 |
84 | MP0000358_abnormal_cell_content/ | 1.00572139 |
85 | MP0002405_respiratory_system_inflammati | 1.00278411 |
86 | MP0001845_abnormal_inflammatory_respons | 0.99923467 |
87 | MP0003567_abnormal_fetal_cardiomyocyte | 0.98915496 |
88 | MP0002938_white_spotting | 0.98881469 |
89 | MP0002160_abnormal_reproductive_system | 0.95735096 |
90 | MP0001188_hyperpigmentation | 0.95198584 |
91 | MP0002132_abnormal_respiratory_system | 0.94744984 |
92 | MP0000049_abnormal_middle_ear | 0.94240661 |
93 | MP0002751_abnormal_autonomic_nervous | 0.93067934 |
94 | MP0008872_abnormal_physiological_respon | 0.92681162 |
95 | MP0003698_abnormal_male_reproductive | 0.92154820 |
96 | MP0002736_abnormal_nociception_after | 0.92149793 |
97 | MP0008995_early_reproductive_senescence | 0.91716628 |
98 | MP0000703_abnormal_thymus_morphology | 0.91230935 |
99 | MP0001905_abnormal_dopamine_level | 0.90325460 |
100 | MP0003763_abnormal_thymus_physiology | 0.90115783 |
101 | MP0000653_abnormal_sex_gland | 0.89725106 |
102 | MP0000750_abnormal_muscle_regeneration | 0.89199159 |
103 | MP0003984_embryonic_growth_retardation | 0.87482841 |
104 | MP0002095_abnormal_skin_pigmentation | 0.87435104 |
105 | MP0003938_abnormal_ear_development | 0.86313766 |
106 | MP0002398_abnormal_bone_marrow | 0.86103271 |
107 | MP0002722_abnormal_immune_system | 0.84779480 |
108 | MP0005389_reproductive_system_phenotype | 0.84614927 |
109 | MP0008004_abnormal_stomach_pH | 0.84216313 |
110 | MP0008873_increased_physiological_sensi | 0.83845188 |
111 | MP0005174_abnormal_tail_pigmentation | 0.83340106 |
112 | MP0008469_abnormal_protein_level | 0.82549499 |
113 | MP0001853_heart_inflammation | 0.82156086 |
114 | MP0002088_abnormal_embryonic_growth/wei | 0.82074655 |
115 | MP0000015_abnormal_ear_pigmentation | 0.81305078 |
116 | MP0005379_endocrine/exocrine_gland_phen | 0.80255616 |
117 | MP0001764_abnormal_homeostasis | 0.80128582 |
118 | MP0000689_abnormal_spleen_morphology | 0.78501868 |
119 | MP0002084_abnormal_developmental_patter | 0.78365232 |
120 | MP0005166_decreased_susceptibility_to | 0.77260171 |
121 | MP0002429_abnormal_blood_cell | 0.75943066 |
122 | MP0003941_abnormal_skin_development | 0.75809387 |
123 | MP0000566_synostosis | 0.75800139 |
124 | MP0003119_abnormal_digestive_system | 0.74047090 |
125 | MP0004808_abnormal_hematopoietic_stem | 0.73845881 |
126 | MP0000372_irregular_coat_pigmentation | 0.73386650 |
127 | MP0006082_CNS_inflammation | 0.72890943 |
128 | MP0002111_abnormal_tail_morphology | 0.71310763 |
129 | MP0001919_abnormal_reproductive_system | 0.69129380 |
130 | MP0002148_abnormal_hypersensitivity_rea | 0.65568724 |
131 | MP0005395_other_phenotype | 0.65381994 |
132 | MP0001293_anophthalmia | 0.64730316 |
133 | MP0005671_abnormal_response_to | 0.64707370 |
134 | MP0000716_abnormal_immune_system | 0.63526392 |
135 | MP0005384_cellular_phenotype | 0.63516984 |
136 | MP0005408_hypopigmentation | 0.63099076 |
137 | MP0000858_altered_metastatic_potential | 0.62912013 |
138 | MP0003656_abnormal_erythrocyte_physiolo | 0.61867054 |
139 | MP0004142_abnormal_muscle_tone | 0.60673671 |
140 | MP0003937_abnormal_limbs/digits/tail_de | 0.60200810 |
141 | MP0010030_abnormal_orbit_morphology | 0.59187871 |
142 | MP0001119_abnormal_female_reproductive | 0.58233348 |
143 | MP0002086_abnormal_extraembryonic_tissu | 0.56481690 |
144 | MP0005397_hematopoietic_system_phenotyp | 0.56310171 |
145 | MP0001545_abnormal_hematopoietic_system | 0.56310171 |
146 | MP0010352_gastrointestinal_tract_polyps | 0.56137528 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Reticulocytopenia (HP:0001896) | 5.56494487 |
2 | Abnormality of cells of the erythroid lineage (HP:0012130) | 5.34206812 |
3 | Abnormal number of erythroid precursors (HP:0012131) | 5.02835102 |
4 | Cerebral hypomyelination (HP:0006808) | 4.38194977 |
5 | Birth length less than 3rd percentile (HP:0003561) | 4.36074814 |
6 | Macrocytic anemia (HP:0001972) | 3.91103248 |
7 | Breast hypoplasia (HP:0003187) | 3.87651449 |
8 | Pallor (HP:0000980) | 3.62859459 |
9 | Carpal bone hypoplasia (HP:0001498) | 3.58657687 |
10 | Mitochondrial inheritance (HP:0001427) | 3.46791634 |
11 | Acute necrotizing encephalopathy (HP:0006965) | 3.32049955 |
12 | Rough bone trabeculation (HP:0100670) | 3.31233445 |
13 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 3.31168743 |
14 | Increased hepatocellular lipid droplets (HP:0006565) | 3.26854615 |
15 | Hepatocellular necrosis (HP:0001404) | 3.23645966 |
16 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.18804008 |
17 | Reduced antithrombin III activity (HP:0001976) | 3.12705194 |
18 | Increased CSF lactate (HP:0002490) | 3.05690775 |
19 | 3-Methylglutaconic aciduria (HP:0003535) | 3.05457097 |
20 | Increased muscle lipid content (HP:0009058) | 2.95327482 |
21 | Type I transferrin isoform profile (HP:0003642) | 2.93703900 |
22 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.92507926 |
23 | Patellar aplasia (HP:0006443) | 2.90892987 |
24 | Exertional dyspnea (HP:0002875) | 2.90311699 |
25 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.87790283 |
26 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.87526905 |
27 | Trismus (HP:0000211) | 2.87342546 |
28 | Aplastic anemia (HP:0001915) | 2.87159158 |
29 | Cerebral edema (HP:0002181) | 2.86073935 |
30 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.85683690 |
31 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.84953785 |
32 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.84953785 |
33 | Chromsome breakage (HP:0040012) | 2.81946972 |
34 | Renal Fanconi syndrome (HP:0001994) | 2.80368558 |
35 | Lipid accumulation in hepatocytes (HP:0006561) | 2.77318155 |
36 | Secondary amenorrhea (HP:0000869) | 2.76441519 |
37 | Panhypogammaglobulinemia (HP:0003139) | 2.75436849 |
38 | Increased serum lactate (HP:0002151) | 2.75364875 |
39 | Oral leukoplakia (HP:0002745) | 2.73041403 |
40 | Premature ovarian failure (HP:0008209) | 2.72958828 |
41 | Horseshoe kidney (HP:0000085) | 2.67441890 |
42 | Abnormal trabecular bone morphology (HP:0100671) | 2.66885404 |
43 | Hepatic necrosis (HP:0002605) | 2.65364777 |
44 | Abnormality of the anterior horn cell (HP:0006802) | 2.61255977 |
45 | Degeneration of anterior horn cells (HP:0002398) | 2.61255977 |
46 | Meckel diverticulum (HP:0002245) | 2.60182510 |
47 | Stomatitis (HP:0010280) | 2.57826461 |
48 | Abnormality of the preputium (HP:0100587) | 2.57305111 |
49 | Abnormality of the ileum (HP:0001549) | 2.53584315 |
50 | Absent radius (HP:0003974) | 2.50774667 |
51 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.50594856 |
52 | Increased IgM level (HP:0003496) | 2.48246825 |
53 | Absent thumb (HP:0009777) | 2.46955532 |
54 | Premature graying of hair (HP:0002216) | 2.45860756 |
55 | Duplicated collecting system (HP:0000081) | 2.44749804 |
56 | Molar tooth sign on MRI (HP:0002419) | 2.43432246 |
57 | Abnormality of midbrain morphology (HP:0002418) | 2.43432246 |
58 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.42825347 |
59 | Optic disc pallor (HP:0000543) | 2.42004250 |
60 | Abnormality of the prostate (HP:0008775) | 2.40807603 |
61 | Obstructive lung disease (HP:0006536) | 2.40457528 |
62 | Chronic obstructive pulmonary disease (HP:0006510) | 2.40457528 |
63 | Acute encephalopathy (HP:0006846) | 2.39831534 |
64 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.39256248 |
65 | CNS hypomyelination (HP:0003429) | 2.37255247 |
66 | Abnormality of B cell number (HP:0010975) | 2.37049972 |
67 | Microretrognathia (HP:0000308) | 2.36124997 |
68 | Abnormality of T cell physiology (HP:0011840) | 2.35596069 |
69 | Microvesicular hepatic steatosis (HP:0001414) | 2.35165733 |
70 | Progressive macrocephaly (HP:0004481) | 2.34959769 |
71 | Abnormality of the umbilical cord (HP:0010881) | 2.31820852 |
72 | Delusions (HP:0000746) | 2.30562460 |
73 | Triphalangeal thumb (HP:0001199) | 2.29607407 |
74 | Respiratory difficulties (HP:0002880) | 2.29417300 |
75 | Absent forearm bone (HP:0003953) | 2.28804483 |
76 | Aplasia involving forearm bones (HP:0009822) | 2.28804483 |
77 | IgG deficiency (HP:0004315) | 2.28235197 |
78 | Irregular epiphyses (HP:0010582) | 2.28040749 |
79 | Ureteral duplication (HP:0000073) | 2.26249294 |
80 | Prostate neoplasm (HP:0100787) | 2.24597451 |
81 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.24309119 |
82 | Bone marrow hypocellularity (HP:0005528) | 2.23849947 |
83 | Hypoplasia of the uterus (HP:0000013) | 2.23644386 |
84 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.20279488 |
85 | Exercise intolerance (HP:0003546) | 2.19231847 |
86 | Multiple enchondromatosis (HP:0005701) | 2.18896988 |
87 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 2.17304099 |
88 | Abnormal umbilical cord blood vessels (HP:0011403) | 2.17246277 |
89 | Single umbilical artery (HP:0001195) | 2.17246277 |
90 | Abnormality of the fetal cardiovascular system (HP:0010948) | 2.17246277 |
91 | Lethargy (HP:0001254) | 2.14713514 |
92 | Leukodystrophy (HP:0002415) | 2.14149877 |
93 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.13108788 |
94 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.13108788 |
95 | Abnormal protein glycosylation (HP:0012346) | 2.13108788 |
96 | Abnormal glycosylation (HP:0012345) | 2.13108788 |
97 | 11 pairs of ribs (HP:0000878) | 2.11722131 |
98 | Dicarboxylic aciduria (HP:0003215) | 2.11485723 |
99 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.11485723 |
100 | Pancytopenia (HP:0001876) | 2.10319965 |
101 | Methylmalonic aciduria (HP:0012120) | 2.10037470 |
102 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.09300133 |
103 | B lymphocytopenia (HP:0010976) | 2.08674601 |
104 | Eosinophilia (HP:0001880) | 2.08327759 |
105 | Abnormality of T cells (HP:0002843) | 2.08010837 |
106 | Granulocytopenia (HP:0001913) | 2.07873047 |
107 | Cleft eyelid (HP:0000625) | 2.07816316 |
108 | Hypoplasia of the pons (HP:0012110) | 2.07438124 |
109 | Respiratory failure (HP:0002878) | 2.06911637 |
110 | CNS demyelination (HP:0007305) | 2.06516036 |
111 | Abnormality of the renal collecting system (HP:0004742) | 2.05133826 |
112 | Glossoptosis (HP:0000162) | 2.04683547 |
113 | Increased intramyocellular lipid droplets (HP:0012240) | 2.03821412 |
114 | Pancreatic cysts (HP:0001737) | 2.03791058 |
115 | Agammaglobulinemia (HP:0004432) | 2.03785609 |
116 | Abnormality of glycolysis (HP:0004366) | 2.00728443 |
117 | Increased serum pyruvate (HP:0003542) | 2.00728443 |
118 | Emotional lability (HP:0000712) | 1.99815052 |
119 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.98485903 |
120 | Lactic acidosis (HP:0003128) | 1.98334529 |
121 | Progressive muscle weakness (HP:0003323) | 1.98047474 |
122 | Hypoplasia of the radius (HP:0002984) | 1.97550435 |
123 | Mediastinal lymphadenopathy (HP:0100721) | 1.96820911 |
124 | Hypomagnesemia (HP:0002917) | 1.96566219 |
125 | Abnormality of chromosome stability (HP:0003220) | 1.96286926 |
126 | Impulsivity (HP:0100710) | 1.94855197 |
127 | Poor head control (HP:0002421) | 1.93777424 |
128 | Recurrent fungal infections (HP:0002841) | 1.93677959 |
129 | Severe combined immunodeficiency (HP:0004430) | 1.93284712 |
130 | Sclerocornea (HP:0000647) | 1.93037205 |
131 | Concave nail (HP:0001598) | 1.91798408 |
132 | Muscle fiber atrophy (HP:0100295) | 1.91385299 |
133 | Recurrent bacterial skin infections (HP:0005406) | 1.90045549 |
134 | Abnormality of the columella (HP:0009929) | 1.89944477 |
135 | Abnormality of the pons (HP:0007361) | 1.88593564 |
136 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.88386545 |
137 | Progressive microcephaly (HP:0000253) | 1.88106089 |
138 | Thrombocytosis (HP:0001894) | 1.86532061 |
139 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.86043201 |
140 | Generalized aminoaciduria (HP:0002909) | 1.85284165 |
141 | Unsteady gait (HP:0002317) | 1.85176210 |
142 | Hyperglycinemia (HP:0002154) | 1.84273899 |
143 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.82954810 |
144 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.82770366 |
145 | Pancreatic fibrosis (HP:0100732) | 1.80849719 |
146 | Ragged-red muscle fibers (HP:0003200) | 1.79390515 |
147 | Tetany (HP:0001281) | 1.79280104 |
148 | Abnormality of male internal genitalia (HP:0000022) | 1.76318267 |
149 | Abnormality of magnesium homeostasis (HP:0004921) | 1.73824380 |
150 | Neutropenia (HP:0001875) | 1.73797398 |
151 | Recurrent cutaneous fungal infections (HP:0011370) | 1.72911210 |
152 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.72911210 |
153 | Recurrent viral infections (HP:0004429) | 1.72887136 |
154 | Colon cancer (HP:0003003) | 1.72552893 |
155 | Testicular atrophy (HP:0000029) | 1.71593445 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BUB1 | 5.20975464 |
2 | VRK2 | 5.16227812 |
3 | STK16 | 3.93216229 |
4 | WEE1 | 3.91475123 |
5 | EIF2AK1 | 3.87522730 |
6 | NME2 | 3.77990781 |
7 | PINK1 | 3.19394561 |
8 | TLK1 | 3.13376066 |
9 | SRPK1 | 2.76726750 |
10 | NME1 | 2.64196555 |
11 | BCKDK | 2.25554643 |
12 | VRK1 | 2.20315233 |
13 | CDC7 | 2.18373671 |
14 | MARK3 | 2.07105113 |
15 | PLK4 | 2.01113616 |
16 | PIM2 | 1.97149992 |
17 | EIF2AK3 | 1.95351178 |
18 | TESK2 | 1.91974760 |
19 | TSSK6 | 1.89996170 |
20 | BRSK2 | 1.86636309 |
21 | NUAK1 | 1.86381032 |
22 | ZAK | 1.84243183 |
23 | PLK1 | 1.77438269 |
24 | MKNK2 | 1.71427185 |
25 | MKNK1 | 1.71366063 |
26 | DYRK3 | 1.68667485 |
27 | TTK | 1.64605687 |
28 | PNCK | 1.57789319 |
29 | BMPR1B | 1.57167422 |
30 | CSNK1A1L | 1.51391042 |
31 | AURKA | 1.50134286 |
32 | NEK2 | 1.49341455 |
33 | PLK3 | 1.42008690 |
34 | AURKB | 1.35367649 |
35 | CDK7 | 1.31920671 |
36 | MAP4K2 | 1.30006589 |
37 | PBK | 1.28079822 |
38 | EPHA2 | 1.27614240 |
39 | CSNK1G2 | 1.22341607 |
40 | CHEK2 | 1.16713519 |
41 | PRKD3 | 1.16088962 |
42 | BRSK1 | 1.15785724 |
43 | IRAK4 | 1.15270230 |
44 | TAF1 | 1.11929393 |
45 | FES | 1.11394341 |
46 | ACVR1B | 1.09084547 |
47 | BRAF | 1.07561173 |
48 | DYRK2 | 1.03193171 |
49 | DAPK1 | 1.02469367 |
50 | IRAK3 | 1.01349096 |
51 | MAP3K11 | 0.99615683 |
52 | SMG1 | 0.97908547 |
53 | ARAF | 0.95497852 |
54 | SYK | 0.93123921 |
55 | RPS6KA4 | 0.93085891 |
56 | MST4 | 0.92358899 |
57 | RPS6KB2 | 0.91878374 |
58 | PASK | 0.91270827 |
59 | ATR | 0.90975265 |
60 | EIF2AK2 | 0.89771018 |
61 | IKBKE | 0.86868327 |
62 | PAK1 | 0.86227699 |
63 | CCNB1 | 0.84238880 |
64 | BLK | 0.84164289 |
65 | MAP2K7 | 0.83717709 |
66 | CSNK2A1 | 0.82319671 |
67 | TNK2 | 0.81333385 |
68 | CSNK2A2 | 0.79332082 |
69 | CDK19 | 0.78620798 |
70 | PRKCI | 0.78218760 |
71 | TRIM28 | 0.74251521 |
72 | MAP3K8 | 0.72034755 |
73 | ABL2 | 0.71905691 |
74 | CHEK1 | 0.71830326 |
75 | RPS6KA5 | 0.71125540 |
76 | PDK2 | 0.71114889 |
77 | CDK4 | 0.68536037 |
78 | TBK1 | 0.67695845 |
79 | CDK8 | 0.65272677 |
80 | WNK3 | 0.64278885 |
81 | GRK5 | 0.64276922 |
82 | GRK1 | 0.62410158 |
83 | LRRK2 | 0.62375244 |
84 | CLK1 | 0.61908340 |
85 | PRKCQ | 0.61907934 |
86 | TYK2 | 0.59124783 |
87 | PIM1 | 0.57047045 |
88 | TESK1 | 0.56457105 |
89 | STK4 | 0.56381471 |
90 | FRK | 0.55641118 |
91 | ZAP70 | 0.54510228 |
92 | CDK2 | 0.54075772 |
93 | MAPKAPK5 | 0.52642909 |
94 | SCYL2 | 0.52127639 |
95 | KDR | 0.51703385 |
96 | LATS2 | 0.47188994 |
97 | AKT3 | 0.47049785 |
98 | ADRBK2 | 0.47003548 |
99 | MAPK13 | 0.45938159 |
100 | NEK1 | 0.44682996 |
101 | ATM | 0.44602369 |
102 | MAP2K2 | 0.43445638 |
103 | ITK | 0.43179798 |
104 | LIMK1 | 0.42631997 |
105 | STK24 | 0.41679649 |
106 | CAMKK2 | 0.40771877 |
107 | NLK | 0.39155090 |
108 | MAPK11 | 0.39144087 |
109 | CSNK1G3 | 0.38693036 |
110 | MAP4K1 | 0.38314648 |
111 | ILK | 0.36832979 |
112 | IKBKB | 0.36730262 |
113 | CDK1 | 0.36358307 |
114 | PAK4 | 0.36141190 |
115 | CSNK1E | 0.35983329 |
116 | IRAK2 | 0.33413623 |
117 | CDK9 | 0.32984063 |
118 | TAOK3 | 0.32191752 |
119 | INSRR | 0.32106201 |
120 | MATK | 0.31971198 |
121 | STK38L | 0.31597429 |
122 | TEC | 0.31464214 |
123 | TXK | 0.30550357 |
124 | CDK3 | 0.29146103 |
125 | DAPK3 | 0.28663655 |
126 | CSNK1G1 | 0.28327056 |
127 | BMPR2 | 0.28236381 |
128 | LYN | 0.26705302 |
129 | GRK6 | 0.26263376 |
130 | STK10 | 0.24866190 |
131 | MAP2K6 | 0.23551891 |
132 | MAPKAPK3 | 0.22946717 |
133 | GRK7 | 0.22850389 |
134 | MAPKAPK2 | 0.22218390 |
135 | CDK11A | 0.21483180 |
136 | KIT | 0.21454305 |
137 | BTK | 0.19178854 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ribosome_Homo sapiens_hsa03010 | 5.02429525 |
2 | Proteasome_Homo sapiens_hsa03050 | 4.48980782 |
3 | RNA polymerase_Homo sapiens_hsa03020 | 4.29161521 |
4 | DNA replication_Homo sapiens_hsa03030 | 3.84730588 |
5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.62193368 |
6 | Mismatch repair_Homo sapiens_hsa03430 | 3.36338742 |
7 | Spliceosome_Homo sapiens_hsa03040 | 3.00892698 |
8 | Homologous recombination_Homo sapiens_hsa03440 | 2.88321246 |
9 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.78634235 |
10 | RNA transport_Homo sapiens_hsa03013 | 2.64528642 |
11 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.59193176 |
12 | Base excision repair_Homo sapiens_hsa03410 | 2.41017001 |
13 | Protein export_Homo sapiens_hsa03060 | 2.36724521 |
14 | Basal transcription factors_Homo sapiens_hsa03022 | 2.19892331 |
15 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.13562884 |
16 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.02049939 |
17 | Parkinsons disease_Homo sapiens_hsa05012 | 1.90541996 |
18 | Cell cycle_Homo sapiens_hsa04110 | 1.85749505 |
19 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.78336237 |
20 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.77304803 |
21 | Huntingtons disease_Homo sapiens_hsa05016 | 1.66418970 |
22 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.66368997 |
23 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.66076640 |
24 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.65969638 |
25 | Purine metabolism_Homo sapiens_hsa00230 | 1.59457311 |
26 | RNA degradation_Homo sapiens_hsa03018 | 1.50149881 |
27 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.28038062 |
28 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.26526676 |
29 | Alzheimers disease_Homo sapiens_hsa05010 | 1.18061747 |
30 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.16982169 |
31 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.15547252 |
32 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.12462849 |
33 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.11599810 |
34 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.11444108 |
35 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.04918692 |
36 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.04741765 |
37 | Sulfur relay system_Homo sapiens_hsa04122 | 1.03585626 |
38 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.95781966 |
39 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.89333801 |
40 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.79158802 |
41 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.73084013 |
42 | Leishmaniasis_Homo sapiens_hsa05140 | 0.71339377 |
43 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.69475556 |
44 | Viral myocarditis_Homo sapiens_hsa05416 | 0.67821641 |
45 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.66765929 |
46 | Peroxisome_Homo sapiens_hsa04146 | 0.65032915 |
47 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.64975281 |
48 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.63901732 |
49 | Phototransduction_Homo sapiens_hsa04744 | 0.62095298 |
50 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.61191284 |
51 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.59907616 |
52 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.59111711 |
53 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.58806120 |
54 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.57865260 |
55 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.57096575 |
56 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.55416171 |
57 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.54443096 |
58 | Metabolic pathways_Homo sapiens_hsa01100 | 0.54246750 |
59 | Olfactory transduction_Homo sapiens_hsa04740 | 0.53509501 |
60 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.52921589 |
61 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.51712212 |
62 | Asthma_Homo sapiens_hsa05310 | 0.51692541 |
63 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.50728792 |
64 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.49438797 |
65 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.46832873 |
66 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.46679226 |
67 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.45635230 |
68 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.45254446 |
69 | Other glycan degradation_Homo sapiens_hsa00511 | 0.45002690 |
70 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.43527765 |
71 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.41905061 |
72 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.41527872 |
73 | Tuberculosis_Homo sapiens_hsa05152 | 0.38270194 |
74 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.38206466 |
75 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.38005887 |
76 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.36737970 |
77 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.36580858 |
78 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.36350044 |
79 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.35572604 |
80 | Allograft rejection_Homo sapiens_hsa05330 | 0.34368512 |
81 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.33765978 |
82 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.33683757 |
83 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.33356013 |
84 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.32607593 |
85 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.32472649 |
86 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.32265566 |
87 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.29369969 |
88 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.28571743 |
89 | Legionellosis_Homo sapiens_hsa05134 | 0.26527430 |
90 | HTLV-I infection_Homo sapiens_hsa05166 | 0.25961040 |
91 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.25836455 |
92 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.25410380 |
93 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.25312761 |
94 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.24513151 |
95 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.23438177 |
96 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.22765217 |
97 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.20769228 |
98 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.20141108 |
99 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.18615113 |
100 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.18509448 |
101 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.18281725 |
102 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.18040304 |
103 | Apoptosis_Homo sapiens_hsa04210 | 0.16629769 |
104 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.15828295 |
105 | Alcoholism_Homo sapiens_hsa05034 | 0.15315622 |
106 | Measles_Homo sapiens_hsa05162 | 0.13645893 |
107 | Thyroid cancer_Homo sapiens_hsa05216 | 0.13638762 |
108 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.13442504 |
109 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.12589858 |
110 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.12023117 |
111 | Shigellosis_Homo sapiens_hsa05131 | 0.11950257 |
112 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.10590157 |
113 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.10482482 |
114 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.09709968 |
115 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.09390027 |
116 | Galactose metabolism_Homo sapiens_hsa00052 | 0.06391796 |
117 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.05163426 |
118 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.04713066 |
119 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.04474458 |
120 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.03869729 |
121 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.03846133 |
122 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.03253231 |
123 | Phagosome_Homo sapiens_hsa04145 | 0.01801026 |