Rank | Gene Set | Z-score |
---|---|---|
1 | regulation of translational termination (GO:0006449) | 5.77017939 |
2 | pre-miRNA processing (GO:0031054) | 5.51561719 |
3 | Golgi transport vesicle coating (GO:0048200) | 5.28623910 |
4 | COPI coating of Golgi vesicle (GO:0048205) | 5.28623910 |
5 | regulation of translational fidelity (GO:0006450) | 4.90512340 |
6 | peptidyl-arginine omega-N-methylation (GO:0035247) | 4.40641023 |
7 | nuclear pore organization (GO:0006999) | 4.37072634 |
8 | folic acid-containing compound biosynthetic process (GO:0009396) | 4.32765114 |
9 | DNA unwinding involved in DNA replication (GO:0006268) | 4.29838288 |
10 | proline biosynthetic process (GO:0006561) | 4.23047258 |
11 | nuclear pore complex assembly (GO:0051292) | 4.22311871 |
12 | peptidyl-arginine N-methylation (GO:0035246) | 4.18519048 |
13 | peptidyl-arginine methylation (GO:0018216) | 4.18519048 |
14 | IMP biosynthetic process (GO:0006188) | 4.13120635 |
15 | negative regulation of histone methylation (GO:0031061) | 4.07603163 |
16 | heterochromatin organization (GO:0070828) | 4.06362353 |
17 | mitotic chromosome condensation (GO:0007076) | 4.03382885 |
18 | hemidesmosome assembly (GO:0031581) | 4.02904299 |
19 | regulation of posttranscriptional gene silencing (GO:0060147) | 4.01032575 |
20 | regulation of gene silencing by miRNA (GO:0060964) | 4.01032575 |
21 | regulation of gene silencing by RNA (GO:0060966) | 4.01032575 |
22 | mitotic nuclear envelope disassembly (GO:0007077) | 3.96947845 |
23 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 3.94467149 |
24 | nuclear envelope disassembly (GO:0051081) | 3.88316571 |
25 | membrane disassembly (GO:0030397) | 3.88316571 |
26 | protein localization to kinetochore (GO:0034501) | 3.88067701 |
27 | cell-substrate adherens junction assembly (GO:0007045) | 3.82932744 |
28 | focal adhesion assembly (GO:0048041) | 3.82932744 |
29 | histone H4-K12 acetylation (GO:0043983) | 3.81160740 |
30 | cell-substrate junction assembly (GO:0007044) | 3.79213449 |
31 | cellular protein complex localization (GO:0034629) | 3.77564450 |
32 | histone arginine methylation (GO:0034969) | 3.75397759 |
33 | nucleobase biosynthetic process (GO:0046112) | 3.73343827 |
34 | activation of Rac GTPase activity (GO:0032863) | 3.67982496 |
35 | protein localization to endosome (GO:0036010) | 3.61324713 |
36 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 3.52260747 |
37 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.49737462 |
38 | mitotic G1 DNA damage checkpoint (GO:0031571) | 3.46919899 |
39 | IMP metabolic process (GO:0046040) | 3.46653737 |
40 | synaptic vesicle maturation (GO:0016188) | 3.44754854 |
41 | intracellular estrogen receptor signaling pathway (GO:0030520) | 3.44183295 |
42 | DNA duplex unwinding (GO:0032508) | 3.42563281 |
43 | DNA geometric change (GO:0032392) | 3.39287670 |
44 | peptidyl-lysine dimethylation (GO:0018027) | 3.37571602 |
45 | apoptotic process involved in morphogenesis (GO:0060561) | 3.29624898 |
46 | glucocorticoid receptor signaling pathway (GO:0042921) | 3.27117132 |
47 | pentose-phosphate shunt (GO:0006098) | 3.23186394 |
48 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 3.22921599 |
49 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.22151358 |
50 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.22151358 |
51 | nuclear envelope organization (GO:0006998) | 3.21742627 |
52 | regulation of NFAT protein import into nucleus (GO:0051532) | 3.20244803 |
53 | protein export from nucleus (GO:0006611) | 3.19808622 |
54 | histone H4-K5 acetylation (GO:0043981) | 3.18310037 |
55 | histone H4-K8 acetylation (GO:0043982) | 3.18310037 |
56 | formation of translation preinitiation complex (GO:0001731) | 3.18002400 |
57 | histone H2A monoubiquitination (GO:0035518) | 3.14178455 |
58 | NLS-bearing protein import into nucleus (GO:0006607) | 3.13864178 |
59 | dosage compensation (GO:0007549) | 3.13751214 |
60 | locomotory exploration behavior (GO:0035641) | 3.13286160 |
61 | ribosome biogenesis (GO:0042254) | 3.12837038 |
62 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.07511249 |
63 | regulation of translational elongation (GO:0006448) | 3.06710916 |
64 | pore complex assembly (GO:0046931) | 3.04109367 |
65 | mitotic G1/S transition checkpoint (GO:0044819) | 3.02889507 |
66 | mitotic sister chromatid segregation (GO:0000070) | 3.00680604 |
67 | determination of adult lifespan (GO:0008340) | 3.00605744 |
68 | regulation of histone H3-K27 methylation (GO:0061085) | 2.96828826 |
69 | regulation of RNA export from nucleus (GO:0046831) | 2.94792046 |
70 | positive regulation of synapse maturation (GO:0090129) | 2.92894199 |
71 | regulation of hippo signaling (GO:0035330) | 2.92808028 |
72 | regulation of histone H3-K9 methylation (GO:0051570) | 2.92739103 |
73 | negative regulation of cell size (GO:0045792) | 2.91597154 |
74 | protein retention in ER lumen (GO:0006621) | 2.91559210 |
75 | protein localization to chromosome, centromeric region (GO:0071459) | 2.87875622 |
76 | regulation of chromatin binding (GO:0035561) | 2.87172401 |
77 | mitotic sister chromatid cohesion (GO:0007064) | 2.87121645 |
78 | purine nucleobase biosynthetic process (GO:0009113) | 2.85030319 |
79 | nodal signaling pathway (GO:0038092) | 2.84564062 |
80 | DNA replication initiation (GO:0006270) | 2.83884734 |
81 | NADPH regeneration (GO:0006740) | 2.83766009 |
82 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 2.83700330 |
83 | regulation of nucleobase-containing compound transport (GO:0032239) | 2.83235657 |
84 | ribosome assembly (GO:0042255) | 2.80638440 |
85 | layer formation in cerebral cortex (GO:0021819) | 2.80552407 |
86 | maternal placenta development (GO:0001893) | 2.79486449 |
87 | chromatin silencing (GO:0006342) | 2.78312961 |
88 | sister chromatid segregation (GO:0000819) | 2.78225244 |
89 | positive regulation of nuclease activity (GO:0032075) | 2.77895588 |
90 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.76575341 |
91 | negative regulation of mRNA processing (GO:0050686) | 2.76007332 |
92 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 2.75801455 |
93 | chromatin assembly (GO:0031497) | 2.75419947 |
94 | snRNA processing (GO:0016180) | 2.74412012 |
95 | regulation of early endosome to late endosome transport (GO:2000641) | 2.74295026 |
96 | rRNA transcription (GO:0009303) | 2.73590653 |
97 | tRNA methylation (GO:0030488) | 2.73549817 |
98 | establishment of apical/basal cell polarity (GO:0035089) | 2.72925824 |
99 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 2.72630440 |
100 | desmosome organization (GO:0002934) | 2.71881124 |
101 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 2.71605043 |
102 | negative regulation of mRNA metabolic process (GO:1903312) | 2.70755206 |
103 | embryonic process involved in female pregnancy (GO:0060136) | 2.70654640 |
104 | pinocytosis (GO:0006907) | 2.69833275 |
105 | negative regulation of RNA splicing (GO:0033119) | 2.69716705 |
106 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 2.69600865 |
107 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 2.68733162 |
108 | sodium ion export (GO:0071436) | 2.68672064 |
109 | DNA strand elongation (GO:0022616) | 2.68248668 |
110 | positive regulation of gene expression, epigenetic (GO:0045815) | 2.67942561 |
111 | G1 DNA damage checkpoint (GO:0044783) | 2.67850022 |
112 | glucose catabolic process (GO:0006007) | 2.67207237 |
113 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 2.66797822 |
114 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 2.66094874 |
115 | histone H4 acetylation (GO:0043967) | 2.65560641 |
116 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.65510458 |
117 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.65510458 |
118 | mitochondrial fusion (GO:0008053) | 2.64605148 |
119 | histone H4-K16 acetylation (GO:0043984) | 2.63978277 |
120 | chromosome condensation (GO:0030261) | 2.63858591 |
121 | mannose metabolic process (GO:0006013) | 2.63148715 |
122 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.62069430 |
123 | mRNA transport (GO:0051028) | 2.61960084 |
124 | endoplasmic reticulum unfolded protein response (GO:0030968) | 2.61568916 |
125 | negative regulation of histone modification (GO:0031057) | 2.61542181 |
126 | adherens junction assembly (GO:0034333) | 2.60179450 |
127 | folic acid metabolic process (GO:0046655) | 2.59778150 |
128 | skin morphogenesis (GO:0043589) | 2.59533953 |
129 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.58861414 |
130 | anterior/posterior axis specification, embryo (GO:0008595) | 2.57114968 |
131 | nuclear envelope reassembly (GO:0031468) | 2.56949070 |
132 | mitotic nuclear envelope reassembly (GO:0007084) | 2.56949070 |
133 | trophectodermal cell differentiation (GO:0001829) | 2.56863081 |
134 | negative regulation of telomerase activity (GO:0051974) | 2.56633340 |
135 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 2.55816637 |
136 | nucleosome disassembly (GO:0006337) | 2.55468777 |
137 | protein-DNA complex disassembly (GO:0032986) | 2.55468777 |
138 | DNA strand elongation involved in DNA replication (GO:0006271) | 2.54105433 |
139 | basement membrane organization (GO:0071711) | 2.54034512 |
140 | nucleobase-containing small molecule interconversion (GO:0015949) | 2.53602376 |
141 | regulation of nuclease activity (GO:0032069) | 2.53398730 |
142 | epithelial cell-cell adhesion (GO:0090136) | 2.53078455 |
143 | regulation of spindle organization (GO:0090224) | 2.52709812 |
144 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 2.52647142 |
145 | proline metabolic process (GO:0006560) | 2.52452364 |
146 | ER-nucleus signaling pathway (GO:0006984) | 2.52399795 |
147 | gene silencing (GO:0016458) | 2.52001211 |
148 | positive regulation of RNA splicing (GO:0033120) | 2.51484300 |
149 | mRNA stabilization (GO:0048255) | 2.51423427 |
150 | RNA stabilization (GO:0043489) | 2.51423427 |
151 | corticosteroid receptor signaling pathway (GO:0031958) | 2.51172048 |
152 | protein complex localization (GO:0031503) | 2.50240182 |
153 | snRNA metabolic process (GO:0016073) | 2.49815425 |
154 | positive regulation of chromosome segregation (GO:0051984) | 2.49695114 |
155 | negative regulation of gene expression, epigenetic (GO:0045814) | 2.49180184 |
156 | DNA conformation change (GO:0071103) | 2.48392462 |
157 | positive regulation of transcription from RNA polymerase III promoter (GO:0045945) | 2.46514326 |
158 | ncRNA 3-end processing (GO:0043628) | 2.45983640 |
159 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 2.45685004 |
160 | stress fiber assembly (GO:0043149) | 2.43665401 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 6.79923756 |
2 | MYC_22102868_ChIP-Seq_BL_Human | 3.48771232 |
3 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.42986854 |
4 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 3.40890245 |
5 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.12566791 |
6 | * EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.05390671 |
7 | * MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.85291445 |
8 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.68361251 |
9 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 2.55965066 |
10 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.48232007 |
11 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 2.28191389 |
12 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 2.26532089 |
13 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 2.25149530 |
14 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.21878923 |
15 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 2.05310971 |
16 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.99131979 |
17 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.95871773 |
18 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.93256802 |
19 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.90121800 |
20 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.89525913 |
21 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.85915452 |
22 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.83379217 |
23 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.83180767 |
24 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.80514994 |
25 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.78486945 |
26 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.74993537 |
27 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.74107321 |
28 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.70725902 |
29 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.69979420 |
30 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.69570044 |
31 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.68634403 |
32 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.66965366 |
33 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.66305192 |
34 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.65798456 |
35 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.64828166 |
36 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.59991706 |
37 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.59910335 |
38 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.58967947 |
39 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.58089437 |
40 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.55636298 |
41 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.54423566 |
42 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.52835450 |
43 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.51407559 |
44 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.48092486 |
45 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.46870282 |
46 | * CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.44408599 |
47 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.44362439 |
48 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.44126190 |
49 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.43065924 |
50 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.42723331 |
51 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.41245038 |
52 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.40190672 |
53 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.39455389 |
54 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.39079523 |
55 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.37179740 |
56 | * CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.36986086 |
57 | * RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.36430816 |
58 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.36320024 |
59 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.36148700 |
60 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.36148700 |
61 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.36148700 |
62 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.35614841 |
63 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.35454387 |
64 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.35390034 |
65 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.35376663 |
66 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.34332585 |
67 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.34244499 |
68 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.33667122 |
69 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.32904456 |
70 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.28853392 |
71 | KDM2B_26808549_Chip-Seq_K562_Human | 1.28683474 |
72 | P68_20966046_ChIP-Seq_HELA_Human | 1.28540175 |
73 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.27290116 |
74 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.26063846 |
75 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.24790104 |
76 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.24042043 |
77 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.23902245 |
78 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.23830365 |
79 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.23638487 |
80 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.22179558 |
81 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.21201057 |
82 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.20850075 |
83 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 1.20609393 |
84 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.19712527 |
85 | ATF3_27146783_Chip-Seq_COLON_Human | 1.18657609 |
86 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 1.18570413 |
87 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.17558992 |
88 | POU5F1_16518401_ChIP-PET_MESCs_Mouse | 1.16552986 |
89 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.16082534 |
90 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.15497779 |
91 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.14922157 |
92 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.13245044 |
93 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.12722596 |
94 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.12404951 |
95 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.12337754 |
96 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.12191407 |
97 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.10996545 |
98 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.10695489 |
99 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.10457026 |
100 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.08931007 |
101 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.08785332 |
102 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.08783135 |
103 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.08658905 |
104 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.08512356 |
105 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.07960820 |
106 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.06911236 |
107 | TFAP2A_17053090_ChIP-ChIP_MCF-7_Human | 1.06715715 |
108 | * ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.06126755 |
109 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.05426193 |
110 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 1.05212262 |
111 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.04861888 |
112 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.04474551 |
113 | MAF_26560356_Chip-Seq_TH2_Human | 1.04251417 |
114 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 1.03393078 |
115 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.03143490 |
116 | UTX_26944678_Chip-Seq_JUKART_Human | 1.02675037 |
117 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.02120538 |
118 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 1.02062519 |
119 | CHD1_26751641_Chip-Seq_LNCaP_Human | 1.01945119 |
120 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.01760771 |
121 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 1.01518324 |
122 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.00882289 |
123 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.00437358 |
124 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.00422318 |
125 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.00176636 |
126 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.99023832 |
127 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.98693412 |
128 | * SOX2_18692474_ChIP-Seq_MESCs_Mouse | 0.98056220 |
129 | MAF_26560356_Chip-Seq_TH1_Human | 0.97786185 |
130 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.97641261 |
131 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 0.97487434 |
132 | * PHF8_20622854_ChIP-Seq_HELA_Human | 0.97334124 |
133 | SMC4_20622854_ChIP-Seq_HELA_Human | 0.97231890 |
134 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.96940518 |
135 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.96498356 |
136 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 0.95649209 |
137 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 0.95083348 |
138 | TP53_22127205_ChIP-Seq_IMR90_Human | 0.93807961 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 4.10755430 |
2 | MP0003111_abnormal_nucleus_morphology | 3.42084546 |
3 | MP0010352_gastrointestinal_tract_polyps | 3.19104736 |
4 | MP0005451_abnormal_body_composition | 3.18756004 |
5 | MP0003705_abnormal_hypodermis_morpholog | 2.98918726 |
6 | MP0004957_abnormal_blastocyst_morpholog | 2.79847505 |
7 | MP0008438_abnormal_cutaneous_collagen | 2.75492360 |
8 | MP0005076_abnormal_cell_differentiation | 2.74420591 |
9 | MP0010094_abnormal_chromosome_stability | 2.69789498 |
10 | MP0003123_paternal_imprinting | 2.66517122 |
11 | MP0003693_abnormal_embryo_hatching | 2.59501608 |
12 | MP0001730_embryonic_growth_arrest | 2.58105336 |
13 | MP0003077_abnormal_cell_cycle | 2.48471766 |
14 | MP0008961_abnormal_basal_metabolism | 2.34454797 |
15 | MP0002653_abnormal_ependyma_morphology | 2.27723216 |
16 | MP0008057_abnormal_DNA_replication | 2.24623878 |
17 | MP0002796_impaired_skin_barrier | 2.19537529 |
18 | MP0003283_abnormal_digestive_organ | 2.19510851 |
19 | MP0010307_abnormal_tumor_latency | 2.12075551 |
20 | MP0000350_abnormal_cell_proliferation | 2.09221441 |
21 | MP0002084_abnormal_developmental_patter | 1.97032314 |
22 | MP0001849_ear_inflammation | 1.96252788 |
23 | MP0003453_abnormal_keratinocyte_physiol | 1.95143621 |
24 | MP0004858_abnormal_nervous_system | 1.93788450 |
25 | MP0008260_abnormal_autophagy | 1.88770605 |
26 | MP0010234_abnormal_vibrissa_follicle | 1.88643111 |
27 | MP0002060_abnormal_skin_morphology | 1.87211164 |
28 | MP0004233_abnormal_muscle_weight | 1.87086139 |
29 | MP0001672_abnormal_embryogenesis/_devel | 1.83857047 |
30 | MP0005380_embryogenesis_phenotype | 1.83857047 |
31 | MP0005501_abnormal_skin_physiology | 1.77314934 |
32 | MP0001697_abnormal_embryo_size | 1.73235413 |
33 | MP0002086_abnormal_extraembryonic_tissu | 1.73199649 |
34 | MP0004197_abnormal_fetal_growth/weight/ | 1.72509207 |
35 | MP0002085_abnormal_embryonic_tissue | 1.70881862 |
36 | MP0003984_embryonic_growth_retardation | 1.70234588 |
37 | MP0002088_abnormal_embryonic_growth/wei | 1.67069092 |
38 | MP0003119_abnormal_digestive_system | 1.66866063 |
39 | MP0002080_prenatal_lethality | 1.66795241 |
40 | MP0009840_abnormal_foam_cell | 1.66285303 |
41 | MP0003635_abnormal_synaptic_transmissio | 1.63126691 |
42 | MP0004272_abnormal_basement_membrane | 1.54455991 |
43 | MP0002396_abnormal_hematopoietic_system | 1.54319225 |
44 | MP0000579_abnormal_nail_morphology | 1.52774570 |
45 | MP0003890_abnormal_embryonic-extraembry | 1.50491477 |
46 | MP0000678_abnormal_parathyroid_gland | 1.47467446 |
47 | MP0000537_abnormal_urethra_morphology | 1.47102803 |
48 | MP0003121_genomic_imprinting | 1.42676465 |
49 | MP0005058_abnormal_lysosome_morphology | 1.41524657 |
50 | MP0008877_abnormal_DNA_methylation | 1.41127611 |
51 | MP0001661_extended_life_span | 1.37871620 |
52 | MP0005257_abnormal_intraocular_pressure | 1.35194953 |
53 | MP0003566_abnormal_cell_adhesion | 1.34562155 |
54 | MP0001216_abnormal_epidermal_layer | 1.34260022 |
55 | MP0003941_abnormal_skin_development | 1.33020671 |
56 | MP0000858_altered_metastatic_potential | 1.29878616 |
57 | MP0010030_abnormal_orbit_morphology | 1.29795443 |
58 | MP0008007_abnormal_cellular_replicative | 1.28315407 |
59 | MP0002063_abnormal_learning/memory/cond | 1.26735554 |
60 | MP0009672_abnormal_birth_weight | 1.26693772 |
61 | MP0008770_decreased_survivor_rate | 1.23276998 |
62 | MP0004133_heterotaxia | 1.22481281 |
63 | MP0004811_abnormal_neuron_physiology | 1.21463354 |
64 | MP0000751_myopathy | 1.19628080 |
65 | MP0002089_abnormal_postnatal_growth/wei | 1.17465008 |
66 | MP0004185_abnormal_adipocyte_glucose | 1.16665800 |
67 | MP0003172_abnormal_lysosome_physiology | 1.16514990 |
68 | MP0000490_abnormal_crypts_of | 1.16375862 |
69 | MP0000003_abnormal_adipose_tissue | 1.14740813 |
70 | MP0004947_skin_inflammation | 1.13836338 |
71 | MP0002822_catalepsy | 1.13607761 |
72 | MP0004270_analgesia | 1.12268668 |
73 | MP0008058_abnormal_DNA_repair | 1.12032896 |
74 | MP0009278_abnormal_bone_marrow | 1.11715885 |
75 | MP0003763_abnormal_thymus_physiology | 1.11556473 |
76 | MP0005394_taste/olfaction_phenotype | 1.11051102 |
77 | MP0005499_abnormal_olfactory_system | 1.11051102 |
78 | MP0002877_abnormal_melanocyte_morpholog | 1.10667637 |
79 | MP0001915_intracranial_hemorrhage | 1.10604287 |
80 | MP0001348_abnormal_lacrimal_gland | 1.09262635 |
81 | MP0004885_abnormal_endolymph | 1.08749337 |
82 | MP0009703_decreased_birth_body | 1.08010553 |
83 | MP0005409_darkened_coat_color | 1.08002028 |
84 | MP0003861_abnormal_nervous_system | 1.06067007 |
85 | MP0000467_abnormal_esophagus_morphology | 1.05715048 |
86 | MP0002909_abnormal_adrenal_gland | 1.05013805 |
87 | MP0005397_hematopoietic_system_phenotyp | 1.04987122 |
88 | MP0001545_abnormal_hematopoietic_system | 1.04987122 |
89 | MP0004808_abnormal_hematopoietic_stem | 1.03785234 |
90 | MP0002269_muscular_atrophy | 1.01481995 |
91 | MP0003303_peritoneal_inflammation | 1.01369867 |
92 | MP0009333_abnormal_splenocyte_physiolog | 1.00990663 |
93 | MP0008932_abnormal_embryonic_tissue | 0.99073967 |
94 | MP0009931_abnormal_skin_appearance | 0.98546183 |
95 | MP0000759_abnormal_skeletal_muscle | 0.97751252 |
96 | MP0000428_abnormal_craniofacial_morphol | 0.96502029 |
97 | MP0000313_abnormal_cell_death | 0.96335193 |
98 | MP0000733_abnormal_muscle_development | 0.95760174 |
99 | MP0005623_abnormal_meninges_morphology | 0.94937459 |
100 | MP0003122_maternal_imprinting | 0.93044794 |
101 | MP0001873_stomach_inflammation | 0.92333596 |
102 | MP0005375_adipose_tissue_phenotype | 0.91926992 |
103 | MP0009780_abnormal_chondrocyte_physiolo | 0.91816418 |
104 | MP0009053_abnormal_anal_canal | 0.91161400 |
105 | MP0003191_abnormal_cellular_cholesterol | 0.91035375 |
106 | MP0005621_abnormal_cell_physiology | 0.90571091 |
107 | MP0000762_abnormal_tongue_morphology | 0.90481648 |
108 | MP0001293_anophthalmia | 0.88057753 |
109 | MP0010771_integument_phenotype | 0.87325957 |
110 | MP0002019_abnormal_tumor_incidence | 0.84765651 |
111 | MP0005023_abnormal_wound_healing | 0.84613101 |
112 | MP0005384_cellular_phenotype | 0.84597715 |
113 | MP0002254_reproductive_system_inflammat | 0.84238026 |
114 | MP0003329_amyloid_beta_deposits | 0.83993138 |
115 | MP0004087_abnormal_muscle_fiber | 0.83232819 |
116 | MP0005275_abnormal_skin_tensile | 0.82263484 |
117 | MP0003300_gastrointestinal_ulcer | 0.82253012 |
118 | MP0010630_abnormal_cardiac_muscle | 0.82240992 |
119 | MP0003950_abnormal_plasma_membrane | 0.81391663 |
120 | MP0000703_abnormal_thymus_morphology | 0.81042773 |
121 | MP0002152_abnormal_brain_morphology | 0.81018399 |
122 | MP0002925_abnormal_cardiovascular_devel | 0.80905632 |
123 | MP0001243_abnormal_dermal_layer | 0.78984718 |
124 | MP0005666_abnormal_adipose_tissue | 0.78593208 |
125 | MP0004264_abnormal_extraembryonic_tissu | 0.78409380 |
126 | MP0000955_abnormal_spinal_cord | 0.77661892 |
127 | MP0000750_abnormal_muscle_regeneration | 0.77553587 |
128 | MP0000534_abnormal_ureter_morphology | 0.77196301 |
129 | MP0005670_abnormal_white_adipose | 0.77023376 |
130 | MP0003115_abnormal_respiratory_system | 0.76631410 |
131 | MP0000377_abnormal_hair_follicle | 0.75898693 |
132 | MP0000358_abnormal_cell_content/ | 0.75299308 |
133 | MP0002098_abnormal_vibrissa_morphology | 0.74842813 |
134 | MP0003786_premature_aging | 0.74623350 |
135 | MP0002064_seizures | 0.74447458 |
136 | MP0005187_abnormal_penis_morphology | 0.73979222 |
137 | MP0004782_abnormal_surfactant_physiolog | 0.73786327 |
138 | MP0003091_abnormal_cell_migration | 0.73195342 |
139 | MP0003787_abnormal_imprinting | 0.72981895 |
140 | MP0000627_abnormal_mammary_gland | 0.72799892 |
141 | MP0008872_abnormal_physiological_respon | 0.72680182 |
142 | MP0000747_muscle_weakness | 0.69546022 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ependymoma (HP:0002888) | 4.58316956 |
2 | Abnormality of the lower motor neuron (HP:0002366) | 4.40543974 |
3 | Premature rupture of membranes (HP:0001788) | 3.96641670 |
4 | Astrocytoma (HP:0009592) | 3.78121960 |
5 | Abnormality of the astrocytes (HP:0100707) | 3.78121960 |
6 | Hyperacusis (HP:0010780) | 3.55433298 |
7 | Annular pancreas (HP:0001734) | 3.18394359 |
8 | Distal lower limb amyotrophy (HP:0008944) | 3.12836758 |
9 | Protrusio acetabuli (HP:0003179) | 3.06824401 |
10 | Trismus (HP:0000211) | 3.06265606 |
11 | Pointed chin (HP:0000307) | 2.94435283 |
12 | Ulnar bowing (HP:0003031) | 2.84568797 |
13 | Glioma (HP:0009733) | 2.83722113 |
14 | Selective tooth agenesis (HP:0001592) | 2.82074958 |
15 | Broad face (HP:0000283) | 2.80217926 |
16 | Long palpebral fissure (HP:0000637) | 2.78690728 |
17 | Progressive muscle weakness (HP:0003323) | 2.75381006 |
18 | Short nail (HP:0001799) | 2.73508819 |
19 | Distal upper limb amyotrophy (HP:0007149) | 2.73496458 |
20 | Upper limb amyotrophy (HP:0009129) | 2.73496458 |
21 | Hand muscle atrophy (HP:0009130) | 2.73130929 |
22 | Insomnia (HP:0100785) | 2.71562290 |
23 | Abnormality of the labia minora (HP:0012880) | 2.71332752 |
24 | Increased connective tissue (HP:0009025) | 2.68250969 |
25 | Medulloblastoma (HP:0002885) | 2.64945347 |
26 | Neoplasm of the oral cavity (HP:0100649) | 2.58380814 |
27 | Basal cell carcinoma (HP:0002671) | 2.54624452 |
28 | Fragile skin (HP:0001030) | 2.54377944 |
29 | Renal duplication (HP:0000075) | 2.54133654 |
30 | Myokymia (HP:0002411) | 2.53541024 |
31 | Vertebral compression fractures (HP:0002953) | 2.46581124 |
32 | Resting tremor (HP:0002322) | 2.44518667 |
33 | Sparse lateral eyebrow (HP:0005338) | 2.44207559 |
34 | Dysmetric saccades (HP:0000641) | 2.43319326 |
35 | Lower limb amyotrophy (HP:0007210) | 2.41023890 |
36 | Neoplasm of striated muscle (HP:0009728) | 2.40650430 |
37 | Atrophic scars (HP:0001075) | 2.39621822 |
38 | Elbow flexion contracture (HP:0002987) | 2.39480276 |
39 | Amyotrophic lateral sclerosis (HP:0007354) | 2.36060888 |
40 | Ankyloglossia (HP:0010296) | 2.34643418 |
41 | Distal lower limb muscle weakness (HP:0009053) | 2.32066771 |
42 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.31363055 |
43 | Elfin facies (HP:0004428) | 2.30954836 |
44 | Increased nuchal translucency (HP:0010880) | 2.30491986 |
45 | Flat acetabular roof (HP:0003180) | 2.28332326 |
46 | Natal tooth (HP:0000695) | 2.25999693 |
47 | Colon cancer (HP:0003003) | 2.25497632 |
48 | Spinal rigidity (HP:0003306) | 2.24528194 |
49 | Visual hallucinations (HP:0002367) | 2.24405275 |
50 | Disproportionate tall stature (HP:0001519) | 2.23454020 |
51 | Osteolytic defects of the hand bones (HP:0009699) | 2.20155131 |
52 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.20155131 |
53 | Rhabdomyosarcoma (HP:0002859) | 2.18681620 |
54 | Cerebral aneurysm (HP:0004944) | 2.18396556 |
55 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 2.18184562 |
56 | Adenoma sebaceum (HP:0009720) | 2.16743228 |
57 | Angiofibromas (HP:0010615) | 2.16743228 |
58 | Neoplasm of the heart (HP:0100544) | 2.16276706 |
59 | Achilles tendon contracture (HP:0001771) | 2.13964930 |
60 | Impaired smooth pursuit (HP:0007772) | 2.13365167 |
61 | Abnormal neuron morphology (HP:0012757) | 2.12777213 |
62 | Abnormality of the motor neurons (HP:0002450) | 2.12777213 |
63 | Overriding aorta (HP:0002623) | 2.12536758 |
64 | Advanced eruption of teeth (HP:0006288) | 2.11909747 |
65 | Asymmetry of the thorax (HP:0001555) | 2.11592037 |
66 | Premature skin wrinkling (HP:0100678) | 2.11250529 |
67 | Spinal muscular atrophy (HP:0007269) | 2.11019216 |
68 | Ragged-red muscle fibers (HP:0003200) | 2.10424704 |
69 | Abnormality of the thoracic spine (HP:0100711) | 2.09628748 |
70 | Progressive external ophthalmoplegia (HP:0000590) | 2.08560829 |
71 | Bowel diverticulosis (HP:0005222) | 2.07956444 |
72 | Renovascular hypertension (HP:0100817) | 2.06436596 |
73 | Missing ribs (HP:0000921) | 2.04939402 |
74 | Urinary urgency (HP:0000012) | 2.02244778 |
75 | Thin bony cortex (HP:0002753) | 1.99842172 |
76 | Mildly elevated creatine phosphokinase (HP:0008180) | 1.97994687 |
77 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.97554987 |
78 | Fibroma (HP:0010614) | 1.97012690 |
79 | Generalized amyotrophy (HP:0003700) | 1.96750409 |
80 | Impaired vibration sensation in the lower limbs (HP:0002166) | 1.96505965 |
81 | Genu recurvatum (HP:0002816) | 1.95419463 |
82 | Blue sclerae (HP:0000592) | 1.94850242 |
83 | Pelvic girdle muscle weakness (HP:0003749) | 1.94823729 |
84 | Reticulocytosis (HP:0001923) | 1.93401486 |
85 | Pseudobulbar signs (HP:0002200) | 1.93237645 |
86 | Rough bone trabeculation (HP:0100670) | 1.92349741 |
87 | Back pain (HP:0003418) | 1.91009430 |
88 | Abnormality of the anterior horn cell (HP:0006802) | 1.90981884 |
89 | Degeneration of anterior horn cells (HP:0002398) | 1.90981884 |
90 | Urethral obstruction (HP:0000796) | 1.90487919 |
91 | Ankle contracture (HP:0006466) | 1.90385747 |
92 | Milia (HP:0001056) | 1.89447598 |
93 | Abnormality of oral frenula (HP:0000190) | 1.88883642 |
94 | Hemiplegia (HP:0002301) | 1.88845899 |
95 | Short 4th metacarpal (HP:0010044) | 1.88600628 |
96 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.88600628 |
97 | Ridged nail (HP:0001807) | 1.88534261 |
98 | Heterotopia (HP:0002282) | 1.88495105 |
99 | Breast hypoplasia (HP:0003187) | 1.88387247 |
100 | Syringomyelia (HP:0003396) | 1.88162085 |
101 | Spinal cord lesions (HP:0100561) | 1.88162085 |
102 | Abnormality of ocular smooth pursuit (HP:0000617) | 1.88103297 |
103 | Broad palm (HP:0001169) | 1.87191983 |
104 | Microvesicular hepatic steatosis (HP:0001414) | 1.86911891 |
105 | Macroorchidism (HP:0000053) | 1.86302295 |
106 | Reduced subcutaneous adipose tissue (HP:0003758) | 1.85774522 |
107 | Abnormality of the Achilles tendon (HP:0005109) | 1.85764128 |
108 | Fibrous tissue neoplasm (HP:0012316) | 1.85463362 |
109 | Skin tags (HP:0010609) | 1.85389771 |
110 | Abnormal number of incisors (HP:0011064) | 1.85269471 |
111 | Shoulder girdle muscle weakness (HP:0003547) | 1.84778090 |
112 | Mitral regurgitation (HP:0001653) | 1.84676971 |
113 | Long eyelashes (HP:0000527) | 1.84627129 |
114 | Focal seizures (HP:0007359) | 1.82442240 |
115 | Entropion (HP:0000621) | 1.82378792 |
116 | Megalocornea (HP:0000485) | 1.81557748 |
117 | Bladder diverticulum (HP:0000015) | 1.81489794 |
118 | Patellar dislocation (HP:0002999) | 1.79591769 |
119 | Cerebral hypomyelination (HP:0006808) | 1.78536373 |
120 | J-shaped sella turcica (HP:0002680) | 1.77297718 |
121 | Attention deficit hyperactivity disorder (HP:0007018) | 1.76562191 |
122 | Agnosia (HP:0010524) | 1.76504356 |
123 | Proximal placement of thumb (HP:0009623) | 1.76008232 |
124 | Myopathic facies (HP:0002058) | 1.75979784 |
125 | Deep palmar crease (HP:0006191) | 1.75571864 |
126 | Intellectual disability, profound (HP:0002187) | 1.75443378 |
127 | Prominent nose (HP:0000448) | 1.75089984 |
128 | Wormian bones (HP:0002645) | 1.74807718 |
129 | Abnormal social behavior (HP:0012433) | 1.74691205 |
130 | Impaired social interactions (HP:0000735) | 1.74691205 |
131 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.74575497 |
132 | Gastrointestinal carcinoma (HP:0002672) | 1.74575497 |
133 | Obsessive-compulsive behavior (HP:0000722) | 1.73814151 |
134 | Deviation of the thumb (HP:0009603) | 1.73544074 |
135 | Thick nail (HP:0001805) | 1.73494555 |
136 | Stridor (HP:0010307) | 1.72398477 |
137 | Cervical subluxation (HP:0003308) | 1.71619677 |
138 | Trigonocephaly (HP:0000243) | 1.70589057 |
139 | Cafe-au-lait spot (HP:0000957) | 1.70386737 |
140 | Abnormality of the calcaneus (HP:0008364) | 1.70280232 |
141 | Shallow orbits (HP:0000586) | 1.69466164 |
142 | Preauricular skin tag (HP:0000384) | 1.68508552 |
143 | Nail dystrophy (HP:0008404) | 1.68507986 |
144 | Squamous cell carcinoma (HP:0002860) | 1.68371398 |
145 | Malignant neoplasm of the central nervous system (HP:0100836) | 1.66680928 |
146 | Abnormality of the salivary glands (HP:0010286) | 1.65311312 |
147 | Abnormal gallbladder physiology (HP:0012438) | 1.64237718 |
148 | Cholecystitis (HP:0001082) | 1.64237718 |
149 | Thoracic kyphosis (HP:0002942) | 1.64189513 |
150 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.63944466 |
151 | Biconcave vertebral bodies (HP:0004586) | 1.63580302 |
152 | Broad thumb (HP:0011304) | 1.63381286 |
153 | Spastic diplegia (HP:0001264) | 1.62934122 |
154 | Poor eye contact (HP:0000817) | 1.62933002 |
155 | Short 1st metacarpal (HP:0010034) | 1.62702224 |
156 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 1.62702224 |
157 | Abnormality of the diencephalon (HP:0010662) | 1.62443983 |
158 | Difficulty climbing stairs (HP:0003551) | 1.62308046 |
159 | Dislocated radial head (HP:0003083) | 1.61922459 |
160 | Abnormality of skeletal muscle fiber size (HP:0012084) | 1.61817994 |
161 | Short phalanx of the thumb (HP:0009660) | 1.61003745 |
162 | Multiple enchondromatosis (HP:0005701) | 1.60326046 |
163 | Increased variability in muscle fiber diameter (HP:0003557) | 1.60273851 |
164 | Enlarged penis (HP:0000040) | 1.59523068 |
165 | Abnormal ossification of hand bones (HP:0005921) | 1.59179440 |
166 | Limb-girdle muscle atrophy (HP:0003797) | 1.58852012 |
167 | Abnormality of nail color (HP:0100643) | 1.57844361 |
168 | Fragile nails (HP:0001808) | 1.57705274 |
169 | Short humerus (HP:0005792) | 1.57211512 |
170 | Sacral dimple (HP:0000960) | 1.56818423 |
171 | Hypopigmentation of the fundus (HP:0007894) | 1.56703759 |
172 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.56681842 |
173 | Spinal cord compression (HP:0002176) | 1.56455034 |
174 | Abnormality of the umbilical cord (HP:0010881) | 1.55984838 |
175 | Abnormality of dentin (HP:0010299) | 1.55657268 |
176 | Mitral valve prolapse (HP:0001634) | 1.54961907 |
Rank | Gene Set | Z-score |
---|---|---|
1 | SMG1 | 4.30125467 |
2 | CDK12 | 3.64422512 |
3 | EEF2K | 3.51619544 |
4 | TRIB3 | 3.19197128 |
5 | IRAK3 | 3.14579171 |
6 | PRPF4B | 2.86992156 |
7 | NEK1 | 2.86208140 |
8 | MAP3K9 | 2.55017926 |
9 | PKN2 | 2.44557982 |
10 | ALK | 2.37978605 |
11 | NME2 | 2.33302748 |
12 | MST1R | 2.29339355 |
13 | PRKD3 | 2.24316189 |
14 | CDC7 | 2.17882564 |
15 | SCYL2 | 2.14230121 |
16 | MAP3K10 | 2.07499539 |
17 | TAOK1 | 2.07448201 |
18 | LATS2 | 1.91585421 |
19 | KSR2 | 1.88815044 |
20 | TSSK6 | 1.87183577 |
21 | TYRO3 | 1.76003073 |
22 | ICK | 1.71484904 |
23 | PAK6 | 1.66371382 |
24 | FGFR4 | 1.57203442 |
25 | NEK2 | 1.46843397 |
26 | PTK2 | 1.42726196 |
27 | RIPK1 | 1.39161055 |
28 | MET | 1.38184152 |
29 | PDGFRA | 1.37803164 |
30 | CAMKK1 | 1.35277111 |
31 | NTRK3 | 1.33242811 |
32 | RPS6KB2 | 1.32406187 |
33 | KSR1 | 1.27639117 |
34 | MTOR | 1.26245685 |
35 | MINK1 | 1.21696032 |
36 | WEE1 | 1.20669587 |
37 | DAPK1 | 1.17251000 |
38 | SIK2 | 1.16575653 |
39 | MAP3K13 | 1.14911302 |
40 | EPHA4 | 1.09458216 |
41 | BRD4 | 1.09181897 |
42 | NTRK2 | 1.08753977 |
43 | MAP3K8 | 1.07067598 |
44 | TESK1 | 1.07056279 |
45 | SRPK1 | 1.05847083 |
46 | CDK4 | 1.05396447 |
47 | TTK | 1.02831574 |
48 | EPHA2 | 1.02762883 |
49 | BMX | 1.02378386 |
50 | BUB1 | 1.01297245 |
51 | ARAF | 1.00298048 |
52 | CHEK1 | 0.99610709 |
53 | CDK7 | 0.99060471 |
54 | LMTK2 | 0.98016409 |
55 | TESK2 | 0.96010846 |
56 | PIM2 | 0.94704459 |
57 | PASK | 0.94369257 |
58 | STK38 | 0.94153902 |
59 | MAP3K11 | 0.93429509 |
60 | PAK4 | 0.91042064 |
61 | DAPK2 | 0.90288949 |
62 | MAP3K4 | 0.89030802 |
63 | MAPK11 | 0.88921538 |
64 | EIF2AK1 | 0.86729254 |
65 | CDK2 | 0.86446728 |
66 | ATR | 0.86436423 |
67 | RAF1 | 0.85836211 |
68 | BRSK1 | 0.81178059 |
69 | PLK1 | 0.75449414 |
70 | GRK6 | 0.74080861 |
71 | ERBB4 | 0.73050130 |
72 | BRAF | 0.72550116 |
73 | CSNK1E | 0.71669091 |
74 | FGFR1 | 0.71349143 |
75 | STK10 | 0.71247989 |
76 | EPHB1 | 0.70547590 |
77 | PNCK | 0.68000752 |
78 | NTRK1 | 0.67679097 |
79 | ERN1 | 0.67343359 |
80 | PAK2 | 0.67186795 |
81 | CDC42BPA | 0.65316275 |
82 | PRKD2 | 0.64696433 |
83 | TAOK2 | 0.64675008 |
84 | MAP4K1 | 0.63855407 |
85 | MAP3K14 | 0.63567455 |
86 | MARK1 | 0.63475021 |
87 | LRRK2 | 0.63248233 |
88 | CAMK1D | 0.62762333 |
89 | UHMK1 | 0.62372968 |
90 | MAP3K3 | 0.61757788 |
91 | AKT2 | 0.61622606 |
92 | MARK2 | 0.61520077 |
93 | PLK3 | 0.59430623 |
94 | RET | 0.58655097 |
95 | CDK15 | 0.57989127 |
96 | PTK6 | 0.57561418 |
97 | MAP3K7 | 0.57132236 |
98 | CDK18 | 0.56194996 |
99 | CAMK4 | 0.54405500 |
100 | CDK9 | 0.54339327 |
101 | CDK8 | 0.54044768 |
102 | DDR2 | 0.54029279 |
103 | CDK11A | 0.53884491 |
104 | CLK1 | 0.53675327 |
105 | MAPK10 | 0.53293984 |
106 | RPS6KA2 | 0.53261030 |
107 | CDK6 | 0.53175738 |
108 | PRKCH | 0.51963000 |
109 | STK11 | 0.50660960 |
110 | TTN | 0.50388757 |
111 | MOS | 0.50170927 |
112 | RPS6KA1 | 0.49956252 |
113 | MAP3K1 | 0.49780633 |
114 | CSNK1D | 0.49551637 |
115 | CDK1 | 0.49015377 |
116 | CHEK2 | 0.48749050 |
117 | MAPKAPK3 | 0.48123008 |
118 | AURKB | 0.47394488 |
119 | FLT3 | 0.47169408 |
120 | CDK14 | 0.46506314 |
121 | LATS1 | 0.46081524 |
122 | CAMK1G | 0.45863037 |
123 | ATM | 0.45844856 |
124 | PDPK1 | 0.45630007 |
125 | AURKA | 0.45116221 |
126 | GSK3B | 0.44034113 |
127 | IRAK2 | 0.43781676 |
128 | CDK5 | 0.43480136 |
129 | PAK1 | 0.43185848 |
130 | PBK | 0.42657710 |
131 | MAP2K4 | 0.42613091 |
132 | MELK | 0.41673424 |
133 | MAP2K3 | 0.41235103 |
134 | MAP3K6 | 0.41077091 |
135 | TAF1 | 0.40082707 |
136 | MAPK14 | 0.39769302 |
137 | SIK1 | 0.39416227 |
138 | ILK | 0.37232844 |
139 | TRPM7 | 0.34988944 |
140 | RPS6KC1 | 0.34474549 |
141 | RPS6KL1 | 0.34474549 |
142 | JAK3 | 0.32630260 |
143 | PDGFRB | 0.32037170 |
144 | STK4 | 0.30824510 |
145 | PRKCI | 0.29425651 |
Rank | Gene Set | Z-score |
---|---|---|
1 | RNA transport_Homo sapiens_hsa03013 | 2.40514781 |
2 | * Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.29078484 |
3 | DNA replication_Homo sapiens_hsa03030 | 2.21527277 |
4 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.09329714 |
5 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.93561801 |
6 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.92824061 |
7 | Mismatch repair_Homo sapiens_hsa03430 | 1.89014123 |
8 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.85232001 |
9 | Spliceosome_Homo sapiens_hsa03040 | 1.84617900 |
10 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.84010676 |
11 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.81209140 |
12 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.80607590 |
13 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.75689616 |
14 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.64461463 |
15 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.54393589 |
16 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.53724475 |
17 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.45261378 |
18 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.44975812 |
19 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.44634076 |
20 | Base excision repair_Homo sapiens_hsa03410 | 1.38242699 |
21 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.38154744 |
22 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 1.36527320 |
23 | Cell cycle_Homo sapiens_hsa04110 | 1.36404320 |
24 | Long-term potentiation_Homo sapiens_hsa04720 | 1.36127930 |
25 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.35799784 |
26 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.35786187 |
27 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.35688595 |
28 | Glioma_Homo sapiens_hsa05214 | 1.35652829 |
29 | Other glycan degradation_Homo sapiens_hsa00511 | 1.35280211 |
30 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.34248537 |
31 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.33490105 |
32 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.30651115 |
33 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.28364497 |
34 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.27203763 |
35 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.23330570 |
36 | Sulfur relay system_Homo sapiens_hsa04122 | 1.23036543 |
37 | Focal adhesion_Homo sapiens_hsa04510 | 1.16919934 |
38 | Colorectal cancer_Homo sapiens_hsa05210 | 1.16708966 |
39 | Carbon metabolism_Homo sapiens_hsa01200 | 1.15891613 |
40 | Endometrial cancer_Homo sapiens_hsa05213 | 1.13947186 |
41 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.13303724 |
42 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.12096284 |
43 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.10263967 |
44 | Thyroid cancer_Homo sapiens_hsa05216 | 1.10103492 |
45 | Prostate cancer_Homo sapiens_hsa05215 | 1.08118212 |
46 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.07496179 |
47 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.05647577 |
48 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.05554723 |
49 | Apoptosis_Homo sapiens_hsa04210 | 1.03656036 |
50 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.03410169 |
51 | Prion diseases_Homo sapiens_hsa05020 | 1.02747940 |
52 | Hepatitis B_Homo sapiens_hsa05161 | 1.01209260 |
53 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.01164016 |
54 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.96283476 |
55 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.96055806 |
56 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.95963994 |
57 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.95600341 |
58 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.95509307 |
59 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.95447796 |
60 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.94805892 |
61 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.94240171 |
62 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.93421849 |
63 | Galactose metabolism_Homo sapiens_hsa00052 | 0.92672963 |
64 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.92204060 |
65 | Olfactory transduction_Homo sapiens_hsa04740 | 0.92047680 |
66 | Shigellosis_Homo sapiens_hsa05131 | 0.91972634 |
67 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.91635578 |
68 | Bladder cancer_Homo sapiens_hsa05219 | 0.90376821 |
69 | Gap junction_Homo sapiens_hsa04540 | 0.87964630 |
70 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.84894332 |
71 | HTLV-I infection_Homo sapiens_hsa05166 | 0.84732373 |
72 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.84120250 |
73 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.84012422 |
74 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.83323281 |
75 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.83009485 |
76 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.82780836 |
77 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.81637272 |
78 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.80378570 |
79 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.79571128 |
80 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.77439912 |
81 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.77232498 |
82 | Lysine degradation_Homo sapiens_hsa00310 | 0.77095706 |
83 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.76294977 |
84 | Hepatitis C_Homo sapiens_hsa05160 | 0.76090814 |
85 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.75196132 |
86 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.74577936 |
87 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.73692918 |
88 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.73140165 |
89 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.72508421 |
90 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.71437752 |
91 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.70862367 |
92 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.70596014 |
93 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.69733856 |
94 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.69393028 |
95 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.69331812 |
96 | Circadian entrainment_Homo sapiens_hsa04713 | 0.68800522 |
97 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.68689632 |
98 | Influenza A_Homo sapiens_hsa05164 | 0.68638900 |
99 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.68404173 |
100 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.66837302 |
101 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.64859479 |
102 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.64704412 |
103 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.63010645 |
104 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.62992830 |
105 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.62914769 |
106 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.62666656 |
107 | Amoebiasis_Homo sapiens_hsa05146 | 0.62007210 |
108 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.61972666 |
109 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.61013780 |
110 | Cocaine addiction_Homo sapiens_hsa05030 | 0.60547446 |
111 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.60219243 |
112 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.59628514 |
113 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.59380888 |
114 | Measles_Homo sapiens_hsa05162 | 0.58815858 |
115 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.58450203 |
116 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.58275610 |
117 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.58127166 |
118 | Melanogenesis_Homo sapiens_hsa04916 | 0.57278242 |
119 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.57096551 |
120 | Endocytosis_Homo sapiens_hsa04144 | 0.57003109 |
121 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.56519748 |
122 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.56393735 |
123 | Insulin secretion_Homo sapiens_hsa04911 | 0.56350502 |
124 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.56214876 |
125 | GABAergic synapse_Homo sapiens_hsa04727 | 0.56120921 |
126 | Adherens junction_Homo sapiens_hsa04520 | 0.55481697 |
127 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.55111808 |
128 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.54987081 |
129 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.54485634 |
130 | RNA degradation_Homo sapiens_hsa03018 | 0.54009980 |
131 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.53464097 |
132 | Melanoma_Homo sapiens_hsa05218 | 0.53089404 |
133 | Insulin resistance_Homo sapiens_hsa04931 | 0.52771073 |
134 | Pathways in cancer_Homo sapiens_hsa05200 | 0.52451219 |
135 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.52325307 |
136 | Nicotine addiction_Homo sapiens_hsa05033 | 0.52302779 |
137 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.52192446 |
138 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.51679008 |
139 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.50772371 |
140 | Tight junction_Homo sapiens_hsa04530 | 0.50054889 |
141 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.48998229 |