Rank | Gene Set | Z-score |
---|---|---|
1 | piRNA metabolic process (GO:0034587) | 6.85091174 |
2 | nuclear pore complex assembly (GO:0051292) | 6.05765937 |
3 | nuclear pore organization (GO:0006999) | 5.72953679 |
4 | cilium or flagellum-dependent cell motility (GO:0001539) | 5.65600411 |
5 | male meiosis (GO:0007140) | 5.52251953 |
6 | synapsis (GO:0007129) | 5.18229358 |
7 | synaptonemal complex assembly (GO:0007130) | 5.06414991 |
8 | synaptonemal complex organization (GO:0070193) | 4.99991745 |
9 | DNA methylation involved in gamete generation (GO:0043046) | 4.97369980 |
10 | pore complex assembly (GO:0046931) | 4.68618023 |
11 | mitotic metaphase plate congression (GO:0007080) | 4.50516589 |
12 | mitotic sister chromatid cohesion (GO:0007064) | 4.42154910 |
13 | monoubiquitinated protein deubiquitination (GO:0035520) | 4.41445016 |
14 | meiotic nuclear division (GO:0007126) | 4.21878716 |
15 | male meiosis I (GO:0007141) | 4.20337558 |
16 | chromosome organization involved in meiosis (GO:0070192) | 4.20122934 |
17 | metaphase plate congression (GO:0051310) | 4.17456614 |
18 | regulation of centriole replication (GO:0046599) | 4.13787770 |
19 | meiotic chromosome segregation (GO:0045132) | 4.11579467 |
20 | binding of sperm to zona pellucida (GO:0007339) | 4.07732402 |
21 | histone exchange (GO:0043486) | 4.01794282 |
22 | regulation of DNA endoreduplication (GO:0032875) | 4.01411749 |
23 | sperm-egg recognition (GO:0035036) | 3.97971288 |
24 | mitotic nuclear envelope disassembly (GO:0007077) | 3.97852537 |
25 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.97526702 |
26 | gene silencing by RNA (GO:0031047) | 3.97020280 |
27 | centriole replication (GO:0007099) | 3.95345660 |
28 | fusion of sperm to egg plasma membrane (GO:0007342) | 3.92034177 |
29 | protein K6-linked ubiquitination (GO:0085020) | 3.90679780 |
30 | DNA double-strand break processing (GO:0000729) | 3.90190616 |
31 | regulation of meiosis I (GO:0060631) | 3.89596554 |
32 | regulation of histone H3-K9 methylation (GO:0051570) | 3.89367107 |
33 | kinetochore organization (GO:0051383) | 3.87208242 |
34 | protein localization to chromosome, centromeric region (GO:0071459) | 3.86903627 |
35 | protein localization to kinetochore (GO:0034501) | 3.85713659 |
36 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.83931265 |
37 | telomere maintenance via recombination (GO:0000722) | 3.80897740 |
38 | DNA strand elongation (GO:0022616) | 3.78467785 |
39 | chromatin remodeling at centromere (GO:0031055) | 3.77741939 |
40 | mitotic chromosome condensation (GO:0007076) | 3.74515953 |
41 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.73979279 |
42 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.73979279 |
43 | sister chromatid cohesion (GO:0007062) | 3.73482259 |
44 | replication fork processing (GO:0031297) | 3.73459416 |
45 | nuclear envelope disassembly (GO:0051081) | 3.72193764 |
46 | membrane disassembly (GO:0030397) | 3.72193764 |
47 | proteasome assembly (GO:0043248) | 3.72048507 |
48 | meiotic cell cycle (GO:0051321) | 3.70773721 |
49 | mitotic recombination (GO:0006312) | 3.70557643 |
50 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.70255583 |
51 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.69138825 |
52 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.69138825 |
53 | acrosome assembly (GO:0001675) | 3.68308030 |
54 | meiosis I (GO:0007127) | 3.68278923 |
55 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.67651916 |
56 | axonemal dynein complex assembly (GO:0070286) | 3.67159779 |
57 | mitotic sister chromatid segregation (GO:0000070) | 3.66615915 |
58 | spermatid development (GO:0007286) | 3.64463159 |
59 | establishment of chromosome localization (GO:0051303) | 3.62277930 |
60 | regulation of spindle organization (GO:0090224) | 3.59998482 |
61 | regulation of centrosome cycle (GO:0046605) | 3.59228955 |
62 | CENP-A containing nucleosome assembly (GO:0034080) | 3.57730908 |
63 | cell-cell recognition (GO:0009988) | 3.54870693 |
64 | rRNA methylation (GO:0031167) | 3.51852667 |
65 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.49776991 |
66 | regulation of RNA export from nucleus (GO:0046831) | 3.48904538 |
67 | meiotic cell cycle process (GO:1903046) | 3.47231655 |
68 | microtubule depolymerization (GO:0007019) | 3.47189774 |
69 | sister chromatid segregation (GO:0000819) | 3.45243945 |
70 | DNA replication-independent nucleosome organization (GO:0034724) | 3.45216465 |
71 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.45216465 |
72 | rRNA modification (GO:0000154) | 3.44839078 |
73 | double-strand break repair via homologous recombination (GO:0000724) | 3.41329273 |
74 | positive regulation of histone H3-K4 methylation (GO:0051571) | 3.40831551 |
75 | DNA replication initiation (GO:0006270) | 3.38151575 |
76 | nucleobase biosynthetic process (GO:0046112) | 3.37704535 |
77 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 3.37276247 |
78 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 3.37276247 |
79 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 3.37276247 |
80 | recombinational repair (GO:0000725) | 3.37217443 |
81 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.36901796 |
82 | mitotic spindle checkpoint (GO:0071174) | 3.35851654 |
83 | positive regulation of chromosome segregation (GO:0051984) | 3.35074969 |
84 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.33816390 |
85 | non-recombinational repair (GO:0000726) | 3.33816390 |
86 | DNA synthesis involved in DNA repair (GO:0000731) | 3.31371138 |
87 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 3.31250582 |
88 | negative regulation of DNA repair (GO:0045738) | 3.27556893 |
89 | sperm motility (GO:0030317) | 3.27022271 |
90 | regulation of chromosome segregation (GO:0051983) | 3.26627878 |
91 | DNA replication checkpoint (GO:0000076) | 3.25707254 |
92 | heterochromatin organization (GO:0070828) | 3.24141154 |
93 | ribosome assembly (GO:0042255) | 3.23211922 |
94 | IMP biosynthetic process (GO:0006188) | 3.22375591 |
95 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.21542564 |
96 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 3.21542564 |
97 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.21542564 |
98 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.21542564 |
99 | negative regulation of sister chromatid segregation (GO:0033046) | 3.21542564 |
100 | motile cilium assembly (GO:0044458) | 3.20420440 |
101 | multicellular organism reproduction (GO:0032504) | 3.20029363 |
102 | telomere maintenance via telomere lengthening (GO:0010833) | 3.19869089 |
103 | ribosome biogenesis (GO:0042254) | 3.18411238 |
104 | negative regulation of histone methylation (GO:0031061) | 3.17254855 |
105 | kinetochore assembly (GO:0051382) | 3.16946326 |
106 | regulation of mitotic sister chromatid separation (GO:0010965) | 3.16289970 |
107 | regulation of mitotic sister chromatid segregation (GO:0033047) | 3.16289970 |
108 | regulation of sister chromatid segregation (GO:0033045) | 3.16289970 |
109 | negative regulation of chromosome segregation (GO:0051985) | 3.15642489 |
110 | regulation of mitotic spindle organization (GO:0060236) | 3.14940602 |
111 | mitotic spindle assembly checkpoint (GO:0007094) | 3.14732543 |
112 | DNA alkylation (GO:0006305) | 3.14008246 |
113 | DNA methylation (GO:0006306) | 3.14008246 |
114 | spindle assembly checkpoint (GO:0071173) | 3.12442193 |
115 | DNA-dependent DNA replication (GO:0006261) | 3.12077150 |
116 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.11117489 |
117 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.10738386 |
118 | DNA geometric change (GO:0032392) | 3.09266700 |
119 | histone mRNA metabolic process (GO:0008334) | 3.09247885 |
120 | postreplication repair (GO:0006301) | 3.09180478 |
121 | DNA duplex unwinding (GO:0032508) | 3.08853825 |
122 | chromatin assembly or disassembly (GO:0006333) | 3.08813902 |
123 | translesion synthesis (GO:0019985) | 3.08296534 |
124 | DNA ligation (GO:0006266) | 3.07971708 |
125 | histone H2A acetylation (GO:0043968) | 3.06973317 |
126 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.06319499 |
127 | purine nucleobase biosynthetic process (GO:0009113) | 3.05731838 |
128 | chromosome segregation (GO:0007059) | 3.05690404 |
129 | ATP-dependent chromatin remodeling (GO:0043044) | 3.04662457 |
130 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.04089993 |
131 | DNA unwinding involved in DNA replication (GO:0006268) | 3.03427546 |
132 | formation of translation preinitiation complex (GO:0001731) | 3.03090132 |
133 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.02417471 |
134 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 3.02198631 |
135 | regulation of centrosome duplication (GO:0010824) | 3.01888001 |
136 | mitotic G2/M transition checkpoint (GO:0044818) | 3.01749944 |
137 | nucleus organization (GO:0006997) | 3.01302944 |
138 | maturation of 5.8S rRNA (GO:0000460) | 3.00859257 |
139 | spindle checkpoint (GO:0031577) | 3.00142371 |
140 | gene silencing (GO:0016458) | 3.00115007 |
141 | protein localization to chromosome (GO:0034502) | 2.99739578 |
142 | DNA strand elongation involved in DNA replication (GO:0006271) | 2.99447377 |
143 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 2.98989490 |
144 | double-strand break repair (GO:0006302) | 2.98701118 |
145 | reciprocal DNA recombination (GO:0035825) | 2.97986519 |
146 | reciprocal meiotic recombination (GO:0007131) | 2.97986519 |
147 | chaperone-mediated protein complex assembly (GO:0051131) | 2.96861904 |
148 | DNA packaging (GO:0006323) | 2.95240441 |
149 | intra-S DNA damage checkpoint (GO:0031573) | 2.95106822 |
150 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 2.94629014 |
151 | chromatin assembly (GO:0031497) | 2.94628288 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 9.40894132 |
2 | * MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 5.50534297 |
3 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.45925741 |
4 | * E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.04158270 |
5 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.64493124 |
6 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.35975228 |
7 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.86762321 |
8 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.68632443 |
9 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.51267841 |
10 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.49660896 |
11 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.45885130 |
12 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.42755536 |
13 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.36957291 |
14 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.25473960 |
15 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 2.16430147 |
16 | * GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.14010996 |
17 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.13919064 |
18 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.12942068 |
19 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.12107315 |
20 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.12044118 |
21 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.11017814 |
22 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.08065118 |
23 | * VDR_23849224_ChIP-Seq_CD4+_Human | 2.05605354 |
24 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.04715207 |
25 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.01457308 |
26 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.00791708 |
27 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.91537244 |
28 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.90681514 |
29 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.89785194 |
30 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.84964250 |
31 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.82891196 |
32 | * FOXP3_21729870_ChIP-Seq_TREG_Human | 1.79917258 |
33 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.76170119 |
34 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.74595946 |
35 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.73681436 |
36 | * XRN2_22483619_ChIP-Seq_HELA_Human | 1.70033508 |
37 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.66199220 |
38 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.59963400 |
39 | FUS_26573619_Chip-Seq_HEK293_Human | 1.56253276 |
40 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.55755503 |
41 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.55544968 |
42 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.53612495 |
43 | * PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.49659566 |
44 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.49266332 |
45 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.48281949 |
46 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.47480981 |
47 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.44448227 |
48 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.44402397 |
49 | * TTF2_22483619_ChIP-Seq_HELA_Human | 1.40515185 |
50 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.36428078 |
51 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.33539791 |
52 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.30823039 |
53 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.29401971 |
54 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.28780695 |
55 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.26239997 |
56 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.24316022 |
57 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.24039270 |
58 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.22117743 |
59 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.19525828 |
60 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.19020622 |
61 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.16757642 |
62 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.14038022 |
63 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.13949429 |
64 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.12349696 |
65 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.09882118 |
66 | MYC_22102868_ChIP-Seq_BL_Human | 1.09630136 |
67 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.08931915 |
68 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.07652068 |
69 | VDR_22108803_ChIP-Seq_LS180_Human | 1.07538488 |
70 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.07041668 |
71 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.06802338 |
72 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.05232389 |
73 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.05028674 |
74 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.00930329 |
75 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.99886886 |
76 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.99263955 |
77 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.94473488 |
78 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.94198809 |
79 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.93802870 |
80 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 0.92316207 |
81 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.92243213 |
82 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.91439634 |
83 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.89549826 |
84 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.89237610 |
85 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.88397760 |
86 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.85728730 |
87 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.84619971 |
88 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.84375465 |
89 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.84345556 |
90 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 0.84114240 |
91 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.83097862 |
92 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.82841458 |
93 | * TFEB_21752829_ChIP-Seq_HELA_Human | 0.82132924 |
94 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.81513431 |
95 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.81041241 |
96 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.80919881 |
97 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.80725639 |
98 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.80725639 |
99 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.80725639 |
100 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.80110680 |
101 | MYB_26560356_Chip-Seq_TH2_Human | 0.80067400 |
102 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.79250932 |
103 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 0.78962965 |
104 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.78466862 |
105 | * SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.78089833 |
106 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.77966450 |
107 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.77594382 |
108 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.76907230 |
109 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.75622101 |
110 | MYB_26560356_Chip-Seq_TH1_Human | 0.75512070 |
111 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.75314793 |
112 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.74722971 |
113 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.73912293 |
114 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.73073017 |
115 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.71756291 |
116 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.71746496 |
117 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.71672545 |
118 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.71589728 |
119 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.71543648 |
120 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.70925254 |
121 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.70039950 |
122 | EWS_26573619_Chip-Seq_HEK293_Human | 0.69583317 |
123 | * FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.66911803 |
124 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 0.66288991 |
125 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 0.66190449 |
126 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.65378786 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008057_abnormal_DNA_replication | 5.78623650 |
2 | MP0008877_abnormal_DNA_methylation | 5.38315560 |
3 | MP0010094_abnormal_chromosome_stability | 4.73702296 |
4 | MP0003693_abnormal_embryo_hatching | 4.57902676 |
5 | MP0003111_abnormal_nucleus_morphology | 3.96806991 |
6 | MP0005410_abnormal_fertilization | 3.88215870 |
7 | MP0004957_abnormal_blastocyst_morpholog | 3.70595003 |
8 | MP0003077_abnormal_cell_cycle | 3.62007544 |
9 | MP0008058_abnormal_DNA_repair | 3.48732795 |
10 | MP0001929_abnormal_gametogenesis | 2.91073809 |
11 | MP0008007_abnormal_cellular_replicative | 2.81956833 |
12 | MP0002210_abnormal_sex_determination | 2.74577829 |
13 | MP0003123_paternal_imprinting | 2.52720580 |
14 | MP0000569_abnormal_digit_pigmentation | 2.35619733 |
15 | MP0003698_abnormal_male_reproductive | 2.35192625 |
16 | MP0010307_abnormal_tumor_latency | 2.29958821 |
17 | MP0001145_abnormal_male_reproductive | 2.29346319 |
18 | MP0003786_premature_aging | 2.25884197 |
19 | MP0001730_embryonic_growth_arrest | 2.22144301 |
20 | MP0008932_abnormal_embryonic_tissue | 2.15027274 |
21 | MP0000653_abnormal_sex_gland | 2.07249334 |
22 | MP0000350_abnormal_cell_proliferation | 1.94153174 |
23 | MP0010352_gastrointestinal_tract_polyps | 1.90476703 |
24 | MP0003787_abnormal_imprinting | 1.90017683 |
25 | MP0002396_abnormal_hematopoietic_system | 1.88079893 |
26 | MP0000372_irregular_coat_pigmentation | 1.87738726 |
27 | MP0003806_abnormal_nucleotide_metabolis | 1.86783918 |
28 | MP0005174_abnormal_tail_pigmentation | 1.79908563 |
29 | MP0005380_embryogenesis_phenotype | 1.74219935 |
30 | MP0001672_abnormal_embryogenesis/_devel | 1.74219935 |
31 | MP0004808_abnormal_hematopoietic_stem | 1.72501656 |
32 | MP0003121_genomic_imprinting | 1.70707689 |
33 | MP0005075_abnormal_melanosome_morpholog | 1.68761460 |
34 | MP0000015_abnormal_ear_pigmentation | 1.67463709 |
35 | MP0001697_abnormal_embryo_size | 1.64735074 |
36 | MP0003984_embryonic_growth_retardation | 1.57503682 |
37 | MP0002088_abnormal_embryonic_growth/wei | 1.52755851 |
38 | MP0002084_abnormal_developmental_patter | 1.51743111 |
39 | MP0003890_abnormal_embryonic-extraembry | 1.47046647 |
40 | MP0002161_abnormal_fertility/fecundity | 1.47003908 |
41 | MP0003718_maternal_effect | 1.45203589 |
42 | MP0006035_abnormal_mitochondrial_morpho | 1.42639474 |
43 | MP0006036_abnormal_mitochondrial_physio | 1.42329448 |
44 | MP0002085_abnormal_embryonic_tissue | 1.42099760 |
45 | MP0004197_abnormal_fetal_growth/weight/ | 1.41420774 |
46 | MP0002160_abnormal_reproductive_system | 1.38155100 |
47 | MP0002080_prenatal_lethality | 1.37883855 |
48 | MP0002086_abnormal_extraembryonic_tissu | 1.36588452 |
49 | MP0002095_abnormal_skin_pigmentation | 1.33672597 |
50 | MP0002938_white_spotting | 1.30465774 |
51 | MP0009697_abnormal_copulation | 1.28146188 |
52 | MP0005076_abnormal_cell_differentiation | 1.27046758 |
53 | MP0000313_abnormal_cell_death | 1.25534686 |
54 | MP0001661_extended_life_span | 1.23667928 |
55 | MP0003763_abnormal_thymus_physiology | 1.22955830 |
56 | MP0002019_abnormal_tumor_incidence | 1.17383769 |
57 | MP0005408_hypopigmentation | 1.13899519 |
58 | MP0001119_abnormal_female_reproductive | 1.12763324 |
59 | MP0002653_abnormal_ependyma_morphology | 1.10739387 |
60 | MP0006072_abnormal_retinal_apoptosis | 1.09975601 |
61 | MP0001188_hyperpigmentation | 1.08202268 |
62 | MP0008995_early_reproductive_senescence | 1.06362386 |
63 | MP0005389_reproductive_system_phenotype | 1.06200871 |
64 | MP0002102_abnormal_ear_morphology | 1.05349069 |
65 | MP0001293_anophthalmia | 1.04653032 |
66 | MP0003567_abnormal_fetal_cardiomyocyte | 1.00907267 |
67 | MP0000490_abnormal_crypts_of | 1.00216275 |
68 | MP0001853_heart_inflammation | 0.99075215 |
69 | MP0003186_abnormal_redox_activity | 0.97898622 |
70 | MP0000703_abnormal_thymus_morphology | 0.93819840 |
71 | MP0005397_hematopoietic_system_phenotyp | 0.93558529 |
72 | MP0001545_abnormal_hematopoietic_system | 0.93558529 |
73 | MP0001835_abnormal_antigen_presentation | 0.93099943 |
74 | MP0009672_abnormal_birth_weight | 0.88232302 |
75 | MP0001764_abnormal_homeostasis | 0.88160185 |
76 | MP0006292_abnormal_olfactory_placode | 0.84645827 |
77 | MP0003937_abnormal_limbs/digits/tail_de | 0.83997970 |
78 | MP0004264_abnormal_extraembryonic_tissu | 0.81044092 |
79 | MP0002009_preneoplasia | 0.80010646 |
80 | MP0002398_abnormal_bone_marrow | 0.79727478 |
81 | MP0005671_abnormal_response_to | 0.79637190 |
82 | MP0004381_abnormal_hair_follicle | 0.78665893 |
83 | MP0003699_abnormal_female_reproductive | 0.78614646 |
84 | MP0009703_decreased_birth_body | 0.77721156 |
85 | MP0005646_abnormal_pituitary_gland | 0.76041635 |
86 | MP0005266_abnormal_metabolism | 0.75619313 |
87 | MP0003656_abnormal_erythrocyte_physiolo | 0.74829031 |
88 | MP0008789_abnormal_olfactory_epithelium | 0.72789823 |
89 | MP0000427_abnormal_hair_cycle | 0.71907845 |
90 | MP0003646_muscle_fatigue | 0.70697105 |
91 | MP0003315_abnormal_perineum_morphology | 0.70493654 |
92 | MP0000432_abnormal_head_morphology | 0.70155470 |
93 | MP0001915_intracranial_hemorrhage | 0.70092324 |
94 | MP0005384_cellular_phenotype | 0.69617766 |
95 | MP0000689_abnormal_spleen_morphology | 0.69329067 |
96 | MP0005621_abnormal_cell_physiology | 0.68901599 |
97 | MP0004147_increased_porphyrin_level | 0.68194075 |
98 | MP0000647_abnormal_sebaceous_gland | 0.67653418 |
99 | MP0002722_abnormal_immune_system | 0.67498750 |
100 | MP0009333_abnormal_splenocyte_physiolog | 0.67229531 |
101 | MP0002877_abnormal_melanocyte_morpholog | 0.66804382 |
102 | MP0000371_diluted_coat_color | 0.65989262 |
103 | MP0005253_abnormal_eye_physiology | 0.65426493 |
104 | MP0003943_abnormal_hepatobiliary_system | 0.63614737 |
105 | MP0005084_abnormal_gallbladder_morpholo | 0.62592649 |
106 | MP0005551_abnormal_eye_electrophysiolog | 0.62101656 |
107 | MP0003936_abnormal_reproductive_system | 0.61767855 |
108 | MP0002282_abnormal_trachea_morphology | 0.60981047 |
109 | MP0008873_increased_physiological_sensi | 0.60941637 |
110 | MP0000358_abnormal_cell_content/ | 0.60252994 |
111 | MP0003119_abnormal_digestive_system | 0.57841451 |
112 | MP0005647_abnormal_sex_gland | 0.57289242 |
113 | MP0001800_abnormal_humoral_immune | 0.56337058 |
114 | MP0003136_yellow_coat_color | 0.56282038 |
115 | MP0001919_abnormal_reproductive_system | 0.56099191 |
116 | MP0004134_abnormal_chest_morphology | 0.55798201 |
117 | MP0005395_other_phenotype | 0.53826841 |
118 | MP0003950_abnormal_plasma_membrane | 0.52691503 |
119 | MP0001286_abnormal_eye_development | 0.52414803 |
120 | MP0002163_abnormal_gland_morphology | 0.50465080 |
121 | MP0005623_abnormal_meninges_morphology | 0.48583045 |
122 | MP0002429_abnormal_blood_cell | 0.48414034 |
123 | MP0002092_abnormal_eye_morphology | 0.47291868 |
124 | MP0002006_tumorigenesis | 0.45702855 |
125 | MP0002925_abnormal_cardiovascular_devel | 0.45607318 |
126 | MP0003935_abnormal_craniofacial_develop | 0.44695158 |
127 | MP0002114_abnormal_axial_skeleton | 0.44199734 |
128 | MP0000428_abnormal_craniofacial_morphol | 0.42710925 |
129 | MP0000716_abnormal_immune_system | 0.42669311 |
130 | MP0003861_abnormal_nervous_system | 0.42095523 |
131 | MP0002166_altered_tumor_susceptibility | 0.41928526 |
132 | MP0000537_abnormal_urethra_morphology | 0.41144628 |
133 | MP0004233_abnormal_muscle_weight | 0.39640656 |
134 | MP0000266_abnormal_heart_morphology | 0.39170249 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 6.36530698 |
2 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 4.80943063 |
3 | Absent/shortened dynein arms (HP:0200106) | 4.80943063 |
4 | Chromsome breakage (HP:0040012) | 4.16680209 |
5 | Birth length less than 3rd percentile (HP:0003561) | 3.98691900 |
6 | Abnormality of the anterior horn cell (HP:0006802) | 3.97109942 |
7 | Degeneration of anterior horn cells (HP:0002398) | 3.97109942 |
8 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.86128792 |
9 | 11 pairs of ribs (HP:0000878) | 3.78470599 |
10 | Abnormal respiratory motile cilium physiology (HP:0012261) | 3.74442416 |
11 | Rhinitis (HP:0012384) | 3.67360146 |
12 | Chronic bronchitis (HP:0004469) | 3.53977011 |
13 | Abnormality of chromosome stability (HP:0003220) | 3.44934058 |
14 | Abnormal respiratory motile cilium morphology (HP:0005938) | 3.37321730 |
15 | Abnormal respiratory epithelium morphology (HP:0012253) | 3.37321730 |
16 | Abnormal spermatogenesis (HP:0008669) | 3.36710467 |
17 | Supernumerary spleens (HP:0009799) | 3.24051674 |
18 | Impulsivity (HP:0100710) | 3.21813561 |
19 | Volvulus (HP:0002580) | 3.07059753 |
20 | Abnormality of the preputium (HP:0100587) | 3.03138955 |
21 | Selective tooth agenesis (HP:0001592) | 2.99176915 |
22 | Meckel diverticulum (HP:0002245) | 2.97027940 |
23 | Medulloblastoma (HP:0002885) | 2.96384564 |
24 | Abnormality of the lower motor neuron (HP:0002366) | 2.93763119 |
25 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.87252122 |
26 | Abnormality of the ileum (HP:0001549) | 2.81648842 |
27 | Fibular hypoplasia (HP:0003038) | 2.78509235 |
28 | Ectopic kidney (HP:0000086) | 2.76234336 |
29 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.72500335 |
30 | Irregular epiphyses (HP:0010582) | 2.71002590 |
31 | Azoospermia (HP:0000027) | 2.69587509 |
32 | Myelodysplasia (HP:0002863) | 2.67114485 |
33 | Severe combined immunodeficiency (HP:0004430) | 2.66289987 |
34 | B lymphocytopenia (HP:0010976) | 2.66268583 |
35 | Combined immunodeficiency (HP:0005387) | 2.64150109 |
36 | Carpal bone hypoplasia (HP:0001498) | 2.63624461 |
37 | Abnormality of B cell number (HP:0010975) | 2.63026839 |
38 | Abnormal ciliary motility (HP:0012262) | 2.61360932 |
39 | Papillary thyroid carcinoma (HP:0002895) | 2.60009304 |
40 | Missing ribs (HP:0000921) | 2.58652050 |
41 | Infertility (HP:0000789) | 2.58264764 |
42 | Sloping forehead (HP:0000340) | 2.58157335 |
43 | Embryonal renal neoplasm (HP:0011794) | 2.55975718 |
44 | Abnormality of the labia minora (HP:0012880) | 2.54292345 |
45 | Neoplasm of the oral cavity (HP:0100649) | 2.54179955 |
46 | Nephronophthisis (HP:0000090) | 2.52005528 |
47 | Colon cancer (HP:0003003) | 2.50858892 |
48 | Gonadotropin excess (HP:0000837) | 2.48607531 |
49 | Aplastic anemia (HP:0001915) | 2.48387114 |
50 | Duodenal stenosis (HP:0100867) | 2.44267944 |
51 | Small intestinal stenosis (HP:0012848) | 2.44267944 |
52 | Absent frontal sinuses (HP:0002688) | 2.43869596 |
53 | Bronchiectasis (HP:0002110) | 2.41393803 |
54 | Bronchitis (HP:0012387) | 2.41300414 |
55 | Methylmalonic acidemia (HP:0002912) | 2.41051154 |
56 | Prominent nose (HP:0000448) | 2.38384504 |
57 | Renal cortical cysts (HP:0000803) | 2.36973792 |
58 | Entropion (HP:0000621) | 2.36052059 |
59 | Absent epiphyses (HP:0010577) | 2.35774525 |
60 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 2.35774525 |
61 | Rhabdomyosarcoma (HP:0002859) | 2.35224997 |
62 | Ependymoma (HP:0002888) | 2.33073135 |
63 | Panhypogammaglobulinemia (HP:0003139) | 2.32219821 |
64 | Tubulointerstitial nephritis (HP:0001970) | 2.31715953 |
65 | Increased CSF lactate (HP:0002490) | 2.31173435 |
66 | Abnormality of DNA repair (HP:0003254) | 2.30076457 |
67 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.29979966 |
68 | Breast hypoplasia (HP:0003187) | 2.28892666 |
69 | Nasal polyposis (HP:0100582) | 2.28473598 |
70 | Patellar aplasia (HP:0006443) | 2.27986527 |
71 | Acute myeloid leukemia (HP:0004808) | 2.27016386 |
72 | Upper motor neuron abnormality (HP:0002127) | 2.21349935 |
73 | Acute necrotizing encephalopathy (HP:0006965) | 2.19017473 |
74 | Thyroiditis (HP:0100646) | 2.16889358 |
75 | Facial hemangioma (HP:0000329) | 2.16844916 |
76 | Abnormality of alanine metabolism (HP:0010916) | 2.16392225 |
77 | Hyperalaninemia (HP:0003348) | 2.16392225 |
78 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.16392225 |
79 | Microvesicular hepatic steatosis (HP:0001414) | 2.16367168 |
80 | Agnosia (HP:0010524) | 2.14548225 |
81 | Abnormality of the renal cortex (HP:0011035) | 2.13049557 |
82 | Pancreatic cysts (HP:0001737) | 2.12740928 |
83 | Amyotrophic lateral sclerosis (HP:0007354) | 2.12461281 |
84 | Increased serum lactate (HP:0002151) | 2.08592062 |
85 | Oligodactyly (hands) (HP:0001180) | 2.08543116 |
86 | Glioma (HP:0009733) | 2.06975926 |
87 | Increased hepatocellular lipid droplets (HP:0006565) | 2.06672914 |
88 | Abnormality of methionine metabolism (HP:0010901) | 2.06134701 |
89 | Progressive macrocephaly (HP:0004481) | 2.05600547 |
90 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.04176245 |
91 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.04026965 |
92 | Short ribs (HP:0000773) | 2.01982929 |
93 | Neoplasm of the colon (HP:0100273) | 2.01675161 |
94 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.01506708 |
95 | Absent thumb (HP:0009777) | 2.00775357 |
96 | Pancytopenia (HP:0001876) | 1.99882398 |
97 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.99762169 |
98 | Abnormality of the duodenum (HP:0002246) | 1.99743973 |
99 | Molar tooth sign on MRI (HP:0002419) | 1.99360616 |
100 | Abnormality of midbrain morphology (HP:0002418) | 1.99360616 |
101 | Biliary tract neoplasm (HP:0100574) | 1.97938961 |
102 | Bile duct proliferation (HP:0001408) | 1.97750210 |
103 | Abnormal biliary tract physiology (HP:0012439) | 1.97750210 |
104 | Short thumb (HP:0009778) | 1.96558476 |
105 | Bone marrow hypocellularity (HP:0005528) | 1.95958575 |
106 | Aplasia/Hypoplasia of the fibula (HP:0006492) | 1.94446106 |
107 | Abnormal lung lobation (HP:0002101) | 1.94408838 |
108 | Squamous cell carcinoma (HP:0002860) | 1.93732870 |
109 | Clubbing of toes (HP:0100760) | 1.93323980 |
110 | Male infertility (HP:0003251) | 1.92900133 |
111 | Abnormality of the pons (HP:0007361) | 1.92608106 |
112 | Abnormality of the carotid arteries (HP:0005344) | 1.92287185 |
113 | Acute encephalopathy (HP:0006846) | 1.92212500 |
114 | Premature ovarian failure (HP:0008209) | 1.92153434 |
115 | Breast carcinoma (HP:0003002) | 1.92141661 |
116 | Facial cleft (HP:0002006) | 1.91788802 |
117 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.91486187 |
118 | IgG deficiency (HP:0004315) | 1.91380645 |
119 | Pancreatic fibrosis (HP:0100732) | 1.90971873 |
120 | Hypoplasia of the radius (HP:0002984) | 1.90794957 |
121 | Abnormality of the renal medulla (HP:0100957) | 1.88889239 |
122 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.88457436 |
123 | Type I transferrin isoform profile (HP:0003642) | 1.88348702 |
124 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.88170707 |
125 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 1.87607181 |
126 | Hypoplasia of the fovea (HP:0007750) | 1.87607181 |
127 | Cutaneous melanoma (HP:0012056) | 1.87556277 |
128 | Short middle phalanx of the 5th finger (HP:0004220) | 1.87415991 |
129 | Hypoplasia of the pons (HP:0012110) | 1.85936711 |
130 | Basal cell carcinoma (HP:0002671) | 1.84676919 |
131 | Oral leukoplakia (HP:0002745) | 1.84433128 |
132 | Lipid accumulation in hepatocytes (HP:0006561) | 1.83994322 |
133 | Methylmalonic aciduria (HP:0012120) | 1.83597671 |
134 | Posterior subcapsular cataract (HP:0007787) | 1.83395750 |
135 | Astrocytoma (HP:0009592) | 1.83384222 |
136 | Abnormality of the astrocytes (HP:0100707) | 1.83384222 |
137 | Cafe-au-lait spot (HP:0000957) | 1.82985643 |
138 | Abnormality involving the epiphyses of the lower limbs (HP:0006500) | 1.82717687 |
139 | Abnormality of femoral epiphyses (HP:0006499) | 1.82717687 |
140 | Abnormality of the epiphysis of the femoral head (HP:0010574) | 1.81602324 |
141 | Absent radius (HP:0003974) | 1.80570494 |
142 | Deviation of the thumb (HP:0009603) | 1.80248280 |
143 | Increased nuchal translucency (HP:0010880) | 1.80048970 |
144 | Small epiphyses (HP:0010585) | 1.79791646 |
145 | Mitochondrial inheritance (HP:0001427) | 1.78713444 |
146 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 1.77755955 |
147 | Flattened epiphyses (HP:0003071) | 1.76488259 |
148 | Abnormality of the fingertips (HP:0001211) | 1.76148038 |
149 | Deep philtrum (HP:0002002) | 1.75749517 |
150 | Neoplasm of the adrenal cortex (HP:0100641) | 1.74026309 |
151 | Poikiloderma (HP:0001029) | 1.73519965 |
152 | Hepatocellular necrosis (HP:0001404) | 1.73260260 |
153 | 3-Methylglutaconic aciduria (HP:0003535) | 1.72397885 |
154 | Median cleft lip (HP:0000161) | 1.71240724 |
155 | Cerebral edema (HP:0002181) | 1.69564545 |
156 | Hypoplasia of the thymus (HP:0000778) | 1.69300259 |
157 | Abnormality of eosinophils (HP:0001879) | 1.68486839 |
158 | Sensory axonal neuropathy (HP:0003390) | 1.68322171 |
159 | Albinism (HP:0001022) | 1.67738001 |
160 | Increased serum pyruvate (HP:0003542) | 1.67659136 |
161 | Triphalangeal thumb (HP:0001199) | 1.67545329 |
162 | Hepatic necrosis (HP:0002605) | 1.66270836 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CDC7 | 4.90316395 |
2 | PDK4 | 4.55605903 |
3 | PDK3 | 4.55605903 |
4 | WEE1 | 3.50536483 |
5 | NEK2 | 3.14858374 |
6 | CDK12 | 2.99381769 |
7 | PDK2 | 2.89233345 |
8 | SRPK1 | 2.57459265 |
9 | TTK | 2.55421421 |
10 | ACVR1B | 2.43441263 |
11 | EIF2AK1 | 2.39891116 |
12 | PBK | 2.37779083 |
13 | BUB1 | 2.34746532 |
14 | PNCK | 2.21720002 |
15 | TRIM28 | 2.09804662 |
16 | BRSK2 | 2.05346452 |
17 | ATR | 1.93516873 |
18 | PLK4 | 1.93252499 |
19 | PLK1 | 1.90153396 |
20 | PASK | 1.86850894 |
21 | STK38L | 1.80758853 |
22 | MKNK2 | 1.78334426 |
23 | PLK3 | 1.75379856 |
24 | STK3 | 1.74768437 |
25 | CHEK2 | 1.70343208 |
26 | CHEK1 | 1.67970730 |
27 | MKNK1 | 1.66263734 |
28 | TSSK6 | 1.62074908 |
29 | VRK2 | 1.54323872 |
30 | MAP4K2 | 1.53686917 |
31 | LATS1 | 1.51456075 |
32 | AURKB | 1.48625141 |
33 | TAOK3 | 1.47611908 |
34 | PRKD3 | 1.44734870 |
35 | ATM | 1.35242942 |
36 | EIF2AK3 | 1.34994707 |
37 | CDK7 | 1.32307101 |
38 | CDK4 | 1.26643329 |
39 | TNIK | 1.23159735 |
40 | CCNB1 | 1.16728006 |
41 | INSRR | 1.11305844 |
42 | NME1 | 1.10610627 |
43 | TAF1 | 0.96445123 |
44 | CDK2 | 0.96058169 |
45 | VRK1 | 0.92886082 |
46 | RPS6KA4 | 0.91623921 |
47 | DYRK3 | 0.90778566 |
48 | STK10 | 0.89959683 |
49 | MELK | 0.88919969 |
50 | NEK1 | 0.86614956 |
51 | BRD4 | 0.86614933 |
52 | EEF2K | 0.84626414 |
53 | EPHA2 | 0.83376532 |
54 | STK4 | 0.82194610 |
55 | RPS6KB2 | 0.81390515 |
56 | PIM1 | 0.76995971 |
57 | ERBB3 | 0.76364938 |
58 | CDK1 | 0.76358816 |
59 | BRSK1 | 0.76233094 |
60 | CDK6 | 0.75614115 |
61 | MAP3K8 | 0.74997953 |
62 | TESK1 | 0.74266225 |
63 | CDK3 | 0.74012557 |
64 | AURKA | 0.73248964 |
65 | ZAK | 0.72942148 |
66 | RAF1 | 0.72899110 |
67 | NUAK1 | 0.72184557 |
68 | MAP3K3 | 0.71924060 |
69 | ALK | 0.70664564 |
70 | CSNK2A2 | 0.67043320 |
71 | AKT3 | 0.65290177 |
72 | STK24 | 0.64865552 |
73 | CLK1 | 0.63022087 |
74 | STK16 | 0.61919609 |
75 | TGFBR1 | 0.61420816 |
76 | SCYL2 | 0.60663144 |
77 | MTOR | 0.56390112 |
78 | WNK3 | 0.54675896 |
79 | CDK9 | 0.53177204 |
80 | CSNK2A1 | 0.51214681 |
81 | CSNK1E | 0.50893678 |
82 | RPS6KB1 | 0.49718429 |
83 | MARK3 | 0.49319903 |
84 | CSNK1D | 0.49046892 |
85 | PRKDC | 0.48885510 |
86 | CAMK1G | 0.47910832 |
87 | FRK | 0.47243381 |
88 | TLK1 | 0.46560309 |
89 | OXSR1 | 0.45441167 |
90 | LATS2 | 0.44133229 |
91 | MAP3K14 | 0.44107858 |
92 | MAP4K1 | 0.44018426 |
93 | BRAF | 0.43917940 |
94 | MAP3K12 | 0.43832057 |
95 | TESK2 | 0.42775261 |
96 | DMPK | 0.42768855 |
97 | CDK8 | 0.42645201 |
98 | JAK3 | 0.41515806 |
99 | MAPK14 | 0.41330375 |
100 | FGFR1 | 0.40662715 |
101 | NEK9 | 0.40644761 |
102 | ICK | 0.40440503 |
103 | PTK2B | 0.38293081 |
104 | TRPM7 | 0.38124514 |
105 | TXK | 0.35536153 |
106 | MAPK13 | 0.35502806 |
107 | NLK | 0.35168039 |
108 | WNK4 | 0.32789872 |
109 | GSK3B | 0.32106872 |
110 | WNK1 | 0.28870364 |
111 | PRKCI | 0.28621351 |
112 | AKT1 | 0.28037204 |
113 | MST4 | 0.27438555 |
114 | RPS6KA5 | 0.26965919 |
115 | NME2 | 0.26939066 |
116 | BMPR2 | 0.26478511 |
117 | ITK | 0.25423918 |
118 | CDK19 | 0.25273915 |
119 | ERBB4 | 0.25017447 |
120 | BCR | 0.24702294 |
121 | IRAK1 | 0.24118383 |
122 | MAPK1 | 0.24088652 |
123 | TEC | 0.23876424 |
124 | MAP3K5 | 0.22992414 |
125 | BMPR1B | 0.21942317 |
126 | EIF2AK2 | 0.20978051 |
127 | MAPK10 | 0.20152440 |
128 | PLK2 | 0.18292357 |
129 | NEK6 | 0.18086259 |
130 | STK39 | 0.17893435 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 4.47498034 |
2 | DNA replication_Homo sapiens_hsa03030 | 3.77187498 |
3 | RNA transport_Homo sapiens_hsa03013 | 3.74608478 |
4 | Mismatch repair_Homo sapiens_hsa03430 | 3.71279225 |
5 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 3.30925696 |
6 | Basal transcription factors_Homo sapiens_hsa03022 | 3.16940501 |
7 | Homologous recombination_Homo sapiens_hsa03440 | 3.15558894 |
8 | Spliceosome_Homo sapiens_hsa03040 | 3.10614477 |
9 | RNA polymerase_Homo sapiens_hsa03020 | 3.08975210 |
10 | Cell cycle_Homo sapiens_hsa04110 | 3.07578780 |
11 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.74793234 |
12 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.60482350 |
13 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.47167230 |
14 | RNA degradation_Homo sapiens_hsa03018 | 2.47021207 |
15 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 2.45480966 |
16 | Base excision repair_Homo sapiens_hsa03410 | 2.37267307 |
17 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.34146343 |
18 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.19916451 |
19 | Proteasome_Homo sapiens_hsa03050 | 1.95693624 |
20 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.88364215 |
21 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.85505684 |
22 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.67698739 |
23 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.65906449 |
24 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.58956508 |
25 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.50968758 |
26 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.37826546 |
27 | Ribosome_Homo sapiens_hsa03010 | 1.33768163 |
28 | Purine metabolism_Homo sapiens_hsa00230 | 1.32443266 |
29 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.25235938 |
30 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.15146150 |
31 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.13328498 |
32 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.09081015 |
33 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.08881849 |
34 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.08083005 |
35 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.05427995 |
36 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.04399212 |
37 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.02254482 |
38 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.94874609 |
39 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.91306109 |
40 | Parkinsons disease_Homo sapiens_hsa05012 | 0.90143256 |
41 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.89754542 |
42 | Asthma_Homo sapiens_hsa05310 | 0.86448370 |
43 | HTLV-I infection_Homo sapiens_hsa05166 | 0.84985703 |
44 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.81339100 |
45 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.78179831 |
46 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.77654678 |
47 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.76501058 |
48 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.75619773 |
49 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.75286894 |
50 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.70692465 |
51 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.65990092 |
52 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.65676577 |
53 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.62318758 |
54 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.61411144 |
55 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.60003969 |
56 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.58739544 |
57 | Thyroid cancer_Homo sapiens_hsa05216 | 0.58380337 |
58 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.57318604 |
59 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.56150247 |
60 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.54091456 |
61 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.52786496 |
62 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.51666448 |
63 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.50978879 |
64 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.50401949 |
65 | Measles_Homo sapiens_hsa05162 | 0.49215662 |
66 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.47947822 |
67 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.46790208 |
68 | Circadian rhythm_Homo sapiens_hsa04710 | 0.45774706 |
69 | Lysine degradation_Homo sapiens_hsa00310 | 0.45124177 |
70 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.44253973 |
71 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.44069854 |
72 | Legionellosis_Homo sapiens_hsa05134 | 0.43575356 |
73 | Phototransduction_Homo sapiens_hsa04744 | 0.43018309 |
74 | Influenza A_Homo sapiens_hsa05164 | 0.42177744 |
75 | Protein export_Homo sapiens_hsa03060 | 0.39563951 |
76 | Prostate cancer_Homo sapiens_hsa05215 | 0.39434116 |
77 | Colorectal cancer_Homo sapiens_hsa05210 | 0.38147916 |
78 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.37873060 |
79 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.36554596 |
80 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.35933178 |
81 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.35885490 |
82 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.35557872 |
83 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.35061658 |
84 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.34833355 |
85 | Hepatitis B_Homo sapiens_hsa05161 | 0.34771573 |
86 | Metabolic pathways_Homo sapiens_hsa01100 | 0.33470885 |
87 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.32628260 |
88 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.31151663 |
89 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.29725481 |
90 | Alcoholism_Homo sapiens_hsa05034 | 0.29076354 |
91 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.28739360 |
92 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.28215308 |
93 | Adherens junction_Homo sapiens_hsa04520 | 0.27867437 |
94 | Alzheimers disease_Homo sapiens_hsa05010 | 0.27116356 |
95 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.26448984 |
96 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.26034881 |
97 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.25036050 |
98 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.24834671 |
99 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.23117321 |
100 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.23064057 |
101 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.22444165 |
102 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.22346030 |
103 | Pathways in cancer_Homo sapiens_hsa05200 | 0.22154829 |
104 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.21967332 |
105 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.21537162 |
106 | Apoptosis_Homo sapiens_hsa04210 | 0.21339776 |
107 | Huntingtons disease_Homo sapiens_hsa05016 | 0.21188719 |
108 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.20719835 |
109 | Allograft rejection_Homo sapiens_hsa05330 | 0.20601040 |
110 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.20139967 |
111 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.19666475 |
112 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.18955255 |
113 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.18947035 |
114 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.18435310 |
115 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.17695307 |
116 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.16575782 |
117 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.16371996 |
118 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.16243159 |
119 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.16155706 |
120 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.15995004 |
121 | Viral myocarditis_Homo sapiens_hsa05416 | 0.15543308 |
122 | Olfactory transduction_Homo sapiens_hsa04740 | 0.15163732 |
123 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.14865136 |
124 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.14454740 |
125 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.14229248 |
126 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.13683519 |
127 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.13654249 |
128 | Peroxisome_Homo sapiens_hsa04146 | 0.13536855 |
129 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.13269312 |
130 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.12830889 |
131 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.12111241 |
132 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.11867300 |
133 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.11801910 |
134 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.11529656 |
135 | Carbon metabolism_Homo sapiens_hsa01200 | 0.11253200 |
136 | Shigellosis_Homo sapiens_hsa05131 | 0.10954429 |
137 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.10814745 |
138 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.10562688 |
139 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.09549795 |
140 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.07864538 |