NOL9

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore organization (GO:0006999)5.02708046
2protein localization to kinetochore (GO:0034501)4.88402290
3nuclear pore complex assembly (GO:0051292)4.86794934
4nucleobase biosynthetic process (GO:0046112)4.86446956
5behavioral response to nicotine (GO:0035095)4.72578282
6DNA unwinding involved in DNA replication (GO:0006268)4.65590432
7IMP biosynthetic process (GO:0006188)4.55428316
8DNA replication initiation (GO:0006270)4.54816193
9folic acid-containing compound biosynthetic process (GO:0009396)4.51445706
10purine nucleobase biosynthetic process (GO:0009113)4.37609768
11mitotic nuclear envelope disassembly (GO:0007077)4.28601060
12DNA strand elongation involved in DNA replication (GO:0006271)4.16029709
13mitotic metaphase plate congression (GO:0007080)4.10374094
14ribosome biogenesis (GO:0042254)4.08029803
15negative regulation of telomere maintenance (GO:0032205)4.05000802
16pore complex assembly (GO:0046931)4.03495650
17DNA replication checkpoint (GO:0000076)4.03205166
18protein localization to chromosome, centromeric region (GO:0071459)3.99717242
19regulation of gene silencing by RNA (GO:0060966)3.98920747
20regulation of posttranscriptional gene silencing (GO:0060147)3.98920747
21regulation of gene silencing by miRNA (GO:0060964)3.98920747
22DNA strand elongation (GO:0022616)3.96972441
23nuclear envelope disassembly (GO:0051081)3.95317351
24membrane disassembly (GO:0030397)3.95317351
25replication fork processing (GO:0031297)3.93193654
26IMP metabolic process (GO:0046040)3.88207154
27maturation of SSU-rRNA (GO:0030490)3.88145882
28formation of translation preinitiation complex (GO:0001731)3.86487231
29DNA replication-dependent nucleosome organization (GO:0034723)3.84210167
30DNA replication-dependent nucleosome assembly (GO:0006335)3.84210167
31ribosome assembly (GO:0042255)3.82473466
32telomere maintenance via semi-conservative replication (GO:0032201)3.77163240
33DNA deamination (GO:0045006)3.73194203
34negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.69169100
35negative regulation of translation, ncRNA-mediated (GO:0040033)3.69169100
36regulation of translation, ncRNA-mediated (GO:0045974)3.69169100
37pseudouridine synthesis (GO:0001522)3.68724027
38regulation of spindle organization (GO:0090224)3.67184352
39regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.67046356
40negative regulation of histone methylation (GO:0031061)3.63246841
41mitotic sister chromatid segregation (GO:0000070)3.61074315
42negative regulation of DNA-dependent DNA replication (GO:2000104)3.59392313
43regulation of DNA endoreduplication (GO:0032875)3.51810168
44negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.48670086
45somatic hypermutation of immunoglobulin genes (GO:0016446)3.48643357
46somatic diversification of immune receptors via somatic mutation (GO:0002566)3.48643357
47mitotic chromosome condensation (GO:0007076)3.48415029
48protein K6-linked ubiquitination (GO:0085020)3.48320734
49ribonucleoprotein complex biogenesis (GO:0022613)3.46888901
50RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.45658018
51DNA duplex unwinding (GO:0032508)3.45297737
52metaphase plate congression (GO:0051310)3.43461683
53DNA geometric change (GO:0032392)3.42392673
54regulation of histone H3-K9 methylation (GO:0051570)3.41467145
55attachment of spindle microtubules to kinetochore (GO:0008608)3.40075007
56fucose catabolic process (GO:0019317)3.39291910
57L-fucose metabolic process (GO:0042354)3.39291910
58L-fucose catabolic process (GO:0042355)3.39291910
59response to xenobiotic stimulus (GO:0009410)3.37949437
60rRNA catabolic process (GO:0016075)3.36091921
61protein localization to chromosome (GO:0034502)3.34554814
62telomere maintenance via recombination (GO:0000722)3.34004410
63NADH dehydrogenase complex assembly (GO:0010257)3.31486854
64mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.31486854
65mitochondrial respiratory chain complex I assembly (GO:0032981)3.31486854
66sister chromatid segregation (GO:0000819)3.31012225
67heterochromatin organization (GO:0070828)3.30412431
68alternative mRNA splicing, via spliceosome (GO:0000380)3.29241163
69mitotic recombination (GO:0006312)3.28946303
70* rRNA processing (GO:0006364)3.25907374
71chromatin remodeling at centromere (GO:0031055)3.24978217
72maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.24188645
73regulation of telomere maintenance (GO:0032204)3.23861182
74regulation of translational termination (GO:0006449)3.22707712
75regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.20394953
76ribosomal large subunit biogenesis (GO:0042273)3.19731692
77kinetochore organization (GO:0051383)3.19214727
78DNA replication-independent nucleosome assembly (GO:0006336)3.18685633
79DNA replication-independent nucleosome organization (GO:0034724)3.18685633
80peptidyl-arginine omega-N-methylation (GO:0035247)3.18569185
81CENP-A containing nucleosome assembly (GO:0034080)3.17207688
82telomere maintenance via telomere lengthening (GO:0010833)3.16784901
83* rRNA metabolic process (GO:0016072)3.16512721
84recombinational repair (GO:0000725)3.16186023
85negative regulation of mRNA processing (GO:0050686)3.15955422
86regulation of helicase activity (GO:0051095)3.15072624
87double-strand break repair via homologous recombination (GO:0000724)3.14418446
88synapsis (GO:0007129)3.13441032
89folic acid metabolic process (GO:0046655)3.08833487
90regulation of mitotic spindle organization (GO:0060236)3.08041485
91negative regulation of RNA splicing (GO:0033119)3.07538834
92reciprocal meiotic recombination (GO:0007131)3.07424055
93reciprocal DNA recombination (GO:0035825)3.07424055
94regulation of translation in response to stress (GO:0043555)3.05389016
95nuclear envelope organization (GO:0006998)3.05273251
96regulation of hippo signaling (GO:0035330)3.04921966
97regulation of nuclear cell cycle DNA replication (GO:0033262)3.02647920
98translesion synthesis (GO:0019985)3.02358143
99spliceosomal snRNP assembly (GO:0000387)3.00148622
100chromatin assembly or disassembly (GO:0006333)2.98194173
101mitochondrial RNA metabolic process (GO:0000959)2.98090953
102kynurenine metabolic process (GO:0070189)2.97443015
103response to pheromone (GO:0019236)2.97212256
104RNA splicing, via transesterification reactions (GO:0000375)2.95578625
105pre-miRNA processing (GO:0031054)2.94793013
106positive regulation of chromosome segregation (GO:0051984)2.93586246
107establishment of chromosome localization (GO:0051303)2.93491172
108regulation of telomere maintenance via telomerase (GO:0032210)2.92601285
109histone H4-K12 acetylation (GO:0043983)2.91733336
110termination of RNA polymerase II transcription (GO:0006369)2.91303886
111tRNA modification (GO:0006400)2.90620610
112mRNA splicing, via spliceosome (GO:0000398)2.90361495
113RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.90361495
114dosage compensation (GO:0007549)2.89114238
115meiotic chromosome segregation (GO:0045132)2.88799305
116ribosomal small subunit assembly (GO:0000028)2.88589215
117mRNA transport (GO:0051028)2.87451976
118ubiquinone biosynthetic process (GO:0006744)2.86715714
119mitochondrial respiratory chain complex assembly (GO:0033108)2.86705894
120histone arginine methylation (GO:0034969)2.84780971
121intra-S DNA damage checkpoint (GO:0031573)2.84505295
122spindle checkpoint (GO:0031577)2.84132820
123DNA conformation change (GO:0071103)2.83662480
124protein complex biogenesis (GO:0070271)2.83137123
125postreplication repair (GO:0006301)2.83053355
126somatic diversification of immunoglobulins (GO:0016445)2.82715469
127histone-serine phosphorylation (GO:0035404)2.81831436
128kinetochore assembly (GO:0051382)2.81519963
129inner cell mass cell proliferation (GO:0001833)2.80761762
130DNA damage induced protein phosphorylation (GO:0006975)2.80680875
131regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.80390651
132regulation of mitotic spindle checkpoint (GO:1903504)2.80390651
133nucleotide-excision repair, DNA gap filling (GO:0006297)2.80033184
134exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.78755220
135replicative senescence (GO:0090399)2.78493358
136nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.77919173
137peptidyl-arginine methylation (GO:0018216)2.77899044
138peptidyl-arginine N-methylation (GO:0035246)2.77899044
139negative regulation of mRNA metabolic process (GO:1903312)2.77559811
140translational initiation (GO:0006413)2.77395628
141regulation of translational fidelity (GO:0006450)2.77330680
142regulation of centriole replication (GO:0046599)2.77141088
143chromatin assembly (GO:0031497)2.74530337
144tRNA processing (GO:0008033)2.73406834
145resolution of meiotic recombination intermediates (GO:0000712)2.73342810
146indole-containing compound catabolic process (GO:0042436)2.71827077
147indolalkylamine catabolic process (GO:0046218)2.71827077
148tryptophan catabolic process (GO:0006569)2.71827077
149regulation of centrosome cycle (GO:0046605)2.68978901
150somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.67096017
151somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.67096017
152isotype switching (GO:0045190)2.67096017
153snRNA transcription (GO:0009301)2.67074833
154somatic diversification of immune receptors (GO:0002200)2.66330661
155ubiquinone metabolic process (GO:0006743)2.65756772
156protein polyglutamylation (GO:0018095)2.63201789
157ncRNA catabolic process (GO:0034661)2.62826342
158negative regulation of transcription regulatory region DNA binding (GO:2000678)2.59166468
159sulfation (GO:0051923)2.58026146
160male meiosis I (GO:0007141)2.56292981
161respiratory chain complex IV assembly (GO:0008535)2.56213587
162kidney morphogenesis (GO:0060993)2.54854189
163DNA recombination (GO:0006310)2.53725067
164somatic recombination of immunoglobulin gene segments (GO:0016447)2.52695834
165regulation of centrosome duplication (GO:0010824)2.51080953
166positive regulation of mRNA metabolic process (GO:1903313)2.48491324
167telomere maintenance via telomerase (GO:0007004)2.45012787
168positive regulation of mRNA catabolic process (GO:0061014)2.44331043
169somatic cell DNA recombination (GO:0016444)2.43918357
170somatic diversification of immune receptors via germline recombination within a single locus (GO:0002.43918357
171tryptophan metabolic process (GO:0006568)2.43724658
172negative regulation of telomerase activity (GO:0051974)2.40908377
173tRNA methylation (GO:0030488)2.40855390
174DNA double-strand break processing (GO:0000729)2.40183270
175negative regulation by host of viral transcription (GO:0043922)2.40029142
176establishment of protein localization to mitochondrial membrane (GO:0090151)2.38252060
177water-soluble vitamin biosynthetic process (GO:0042364)2.37839386
178neural tube formation (GO:0001841)2.37727593
179indolalkylamine metabolic process (GO:0006586)2.37458686
180DNA-dependent DNA replication (GO:0006261)2.36062464
181protein-cofactor linkage (GO:0018065)2.35582432
182transcription elongation from RNA polymerase I promoter (GO:0006362)2.35059810
183protein K11-linked deubiquitination (GO:0035871)2.34933426
184DNA strand renaturation (GO:0000733)2.34791931

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.56370641
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.32446295
3* MYC_18555785_ChIP-Seq_MESCs_Mouse4.17528301
4ZNF274_21170338_ChIP-Seq_K562_Hela3.70136479
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.61995366
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.30254217
7* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.28290613
8MYC_19079543_ChIP-ChIP_MESCs_Mouse3.06620659
9FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.97964427
10* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.80619079
11VDR_22108803_ChIP-Seq_LS180_Human2.69143375
12* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.54948949
13EGR1_19374776_ChIP-ChIP_THP-1_Human2.52717655
14EWS_26573619_Chip-Seq_HEK293_Human2.52415148
15GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.44044277
16AR_21909140_ChIP-Seq_LNCAP_Human2.29457641
17MYC_22102868_ChIP-Seq_BL_Human2.26939929
18* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.25755929
19EST1_17652178_ChIP-ChIP_JURKAT_Human2.21723570
20KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.17796878
21* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.14941798
22E2F1_21310950_ChIP-Seq_MCF-7_Human2.12983864
23ETS1_20019798_ChIP-Seq_JURKAT_Human2.12496293
24MYC_18940864_ChIP-ChIP_HL60_Human2.12186547
25BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.09656303
26FUS_26573619_Chip-Seq_HEK293_Human2.08434336
27GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.07419692
28* XRN2_22483619_ChIP-Seq_HELA_Human2.07102075
29NANOG_18555785_ChIP-Seq_MESCs_Mouse2.06829816
30IGF1R_20145208_ChIP-Seq_DFB_Human2.06623625
31* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.03768231
32GBX2_23144817_ChIP-Seq_PC3_Human2.03351615
33MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.03041681
34IRF1_19129219_ChIP-ChIP_H3396_Human2.02454721
35POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.99078383
36MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.97316190
37ZFP57_27257070_Chip-Seq_ESCs_Mouse1.92418139
38SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.91292512
39GABP_17652178_ChIP-ChIP_JURKAT_Human1.90257926
40SALL1_21062744_ChIP-ChIP_HESCs_Human1.89615239
41CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.84711510
42RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.84130626
43CREB1_15753290_ChIP-ChIP_HEK293T_Human1.82579952
44MYCN_18555785_ChIP-Seq_MESCs_Mouse1.82122709
45POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.81669152
46POU3F2_20337985_ChIP-ChIP_501MEL_Human1.80189662
47VDR_23849224_ChIP-Seq_CD4+_Human1.76901266
48FLI1_27457419_Chip-Seq_LIVER_Mouse1.74175235
49FOXP3_21729870_ChIP-Seq_TREG_Human1.71882229
50HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.71206692
51EZH2_22144423_ChIP-Seq_EOC_Human1.71127532
52EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.67912349
53CTBP1_25329375_ChIP-Seq_LNCAP_Human1.67712242
54* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.64777039
55DCP1A_22483619_ChIP-Seq_HELA_Human1.62983008
56TAF15_26573619_Chip-Seq_HEK293_Human1.62669206
57TTF2_22483619_ChIP-Seq_HELA_Human1.61167571
58GABP_19822575_ChIP-Seq_HepG2_Human1.60298149
59RBPJ_22232070_ChIP-Seq_NCS_Mouse1.59531679
60POU5F1_16153702_ChIP-ChIP_HESCs_Human1.55861486
61TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.54726551
62STAT3_1855785_ChIP-Seq_MESCs_Mouse1.52865983
63YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.52355478
64CTBP2_25329375_ChIP-Seq_LNCAP_Human1.52243550
65CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.50390725
66PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.49502311
67SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.47977194
68* KDM5A_27292631_Chip-Seq_BREAST_Human1.47188825
69P300_19829295_ChIP-Seq_ESCs_Human1.47126760
70ER_23166858_ChIP-Seq_MCF-7_Human1.46841239
71MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.45178158
72CIITA_25753668_ChIP-Seq_RAJI_Human1.43688110
73THAP11_20581084_ChIP-Seq_MESCs_Mouse1.43002226
74TP53_22573176_ChIP-Seq_HFKS_Human1.41086798
75ZFX_18555785_ChIP-Seq_MESCs_Mouse1.39522155
76TP63_19390658_ChIP-ChIP_HaCaT_Human1.37777130
77ELK1_19687146_ChIP-ChIP_HELA_Human1.36776429
78E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.36030758
79TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.34831034
80* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.32910081
81ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.32386003
82SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.32070229
83STAT3_23295773_ChIP-Seq_U87_Human1.31294482
84* POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.31017816
85SOX2_18555785_ChIP-Seq_MESCs_Mouse1.29262989
86KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.27961472
87KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.27961472
88KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.27961472
89AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.26855395
90POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.26214537
91TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.26214537
92VDR_21846776_ChIP-Seq_THP-1_Human1.25681446
93NOTCH1_21737748_ChIP-Seq_TLL_Human1.25341226
94PCGF2_27294783_Chip-Seq_ESCs_Mouse1.24993348
95* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.24618887
96UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.22872903
97ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.22480681
98BMI1_23680149_ChIP-Seq_NPCS_Mouse1.21233077
99CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.19761789
100TFEB_21752829_ChIP-Seq_HELA_Human1.19105949
101TCF4_23295773_ChIP-Seq_U87_Human1.18826089
102TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.18228814
103CBX2_27304074_Chip-Seq_ESCs_Mouse1.17237017
104ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.17142738
105KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.17001384
106RNF2_27304074_Chip-Seq_NSC_Mouse1.16107375
107NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.15069460
108HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.14598335
109KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.14449261
110SRF_21415370_ChIP-Seq_HL-1_Mouse1.13531329
111HOXB4_20404135_ChIP-ChIP_EML_Mouse1.13524189
112MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.13363247
113* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.12109431
114NANOG_21062744_ChIP-ChIP_HESCs_Human1.12074428
115AR_21572438_ChIP-Seq_LNCaP_Human1.11221760
116PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.10953147
117BCAT_22108803_ChIP-Seq_LS180_Human1.10865829
118IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.10510269
119CBP_20019798_ChIP-Seq_JUKART_Human1.10510269
120CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.10260948
121PCGF2_27294783_Chip-Seq_NPCs_Mouse1.09696025
122TCF3_18692474_ChIP-Seq_MEFs_Mouse1.09373142
123ELF1_17652178_ChIP-ChIP_JURKAT_Human1.08697816
124FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.08351868
125YY1_21170310_ChIP-Seq_MESCs_Mouse1.07779317
126NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.07210146
127ESR1_15608294_ChIP-ChIP_MCF-7_Human1.05422367
128MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.05274660
129HOXB7_26014856_ChIP-Seq_BT474_Human1.05150541
130TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.04540260
131ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.04224607
132* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.02355498
133NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.01898910
134SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.99927716
135* TCF3_18692474_ChIP-Seq_MESCs_Mouse0.99046125
136NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.98170820
137SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.97594084
138PADI4_21655091_ChIP-ChIP_MCF-7_Human0.97586840
139PIAS1_25552417_ChIP-Seq_VCAP_Human0.97316899
140TCF4_22108803_ChIP-Seq_LS180_Human0.95993715
141* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.95138221
142ERG_20887958_ChIP-Seq_HPC-7_Mouse0.94851343
143AR_25329375_ChIP-Seq_VCAP_Human0.94085681
144FOXA1_27270436_Chip-Seq_PROSTATE_Human0.93283620
145FOXA1_25329375_ChIP-Seq_VCAP_Human0.93283620
146SMAD3_21741376_ChIP-Seq_EPCs_Human0.93270392
147SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.92770656
148NR3C1_21868756_ChIP-Seq_MCF10A_Human0.92419158
149CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.92291272
150NANOG_19829295_ChIP-Seq_ESCs_Human0.91911584
151SOX2_19829295_ChIP-Seq_ESCs_Human0.91911584
152LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.91910790
153NCOR_22424771_ChIP-Seq_293T_Human0.91759776
154GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.90990525
155* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.90961969
156FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.90690601
157* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.89763410
158SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.88382933
159NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.88203874
160ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.88139151
161SMAD4_21799915_ChIP-Seq_A2780_Human0.87654848
162* GATA3_21878914_ChIP-Seq_MCF-7_Human0.86619034
163SOX2_16153702_ChIP-ChIP_HESCs_Human0.86418749
164HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.86287401
165SMAD4_21741376_ChIP-Seq_EPCs_Human0.85829053
166FLI1_21867929_ChIP-Seq_TH2_Mouse0.85814510
167AUTS2_25519132_ChIP-Seq_293T-REX_Human0.85435920
168ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.84610921
169TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.84508217

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.81123122
2MP0003111_abnormal_nucleus_morphology4.44188834
3MP0008057_abnormal_DNA_replication4.43991777
4MP0010094_abnormal_chromosome_stability4.37486980
5MP0004957_abnormal_blastocyst_morpholog4.05818621
6MP0003077_abnormal_cell_cycle3.77312750
7MP0003646_muscle_fatigue3.12827889
8MP0008058_abnormal_DNA_repair2.80157931
9MP0008007_abnormal_cellular_replicative2.77147010
10MP0010352_gastrointestinal_tract_polyps2.64190366
11MP0002396_abnormal_hematopoietic_system2.63631218
12MP0000569_abnormal_digit_pigmentation2.49912705
13MP0000350_abnormal_cell_proliferation2.49855289
14MP0001730_embryonic_growth_arrest2.49280910
15MP0003123_paternal_imprinting2.35876438
16MP0001986_abnormal_taste_sensitivity2.31252544
17MP0008932_abnormal_embryonic_tissue2.27546372
18MP0010307_abnormal_tumor_latency2.06375937
19MP0005380_embryogenesis_phenotype2.00485662
20MP0001672_abnormal_embryogenesis/_devel2.00485662
21MP0001697_abnormal_embryo_size1.89887824
22MP0008877_abnormal_DNA_methylation1.88526351
23MP0005076_abnormal_cell_differentiation1.86431770
24MP0002102_abnormal_ear_morphology1.85436701
25MP0000490_abnormal_crypts_of1.82887026
26MP0003786_premature_aging1.80002046
27MP0003984_embryonic_growth_retardation1.79939437
28MP0005551_abnormal_eye_electrophysiolog1.77942500
29MP0002086_abnormal_extraembryonic_tissu1.77242823
30MP0002088_abnormal_embryonic_growth/wei1.75974751
31MP0002084_abnormal_developmental_patter1.70003895
32MP0002085_abnormal_embryonic_tissue1.69604241
33MP0002080_prenatal_lethality1.69441571
34MP0002160_abnormal_reproductive_system1.68384015
35MP0002938_white_spotting1.67410921
36MP0000427_abnormal_hair_cycle1.64500827
37MP0000372_irregular_coat_pigmentation1.63063901
38MP0001968_abnormal_touch/_nociception1.59843473
39MP0003806_abnormal_nucleotide_metabolis1.59379107
40MP0004197_abnormal_fetal_growth/weight/1.59096831
41MP0008872_abnormal_physiological_respon1.57379822
42MP0005645_abnormal_hypothalamus_physiol1.55597946
43MP0002138_abnormal_hepatobiliary_system1.54640514
44MP0003195_calcinosis1.53178439
45MP0004808_abnormal_hematopoietic_stem1.52671408
46MP0002638_abnormal_pupillary_reflex1.50442867
47MP0003136_yellow_coat_color1.50114567
48MP0003890_abnormal_embryonic-extraembry1.48677972
49MP0004142_abnormal_muscle_tone1.47432131
50MP0000631_abnormal_neuroendocrine_gland1.46731208
51MP0001545_abnormal_hematopoietic_system1.46431485
52MP0005397_hematopoietic_system_phenotyp1.46431485
53MP0000537_abnormal_urethra_morphology1.46092930
54MP0003718_maternal_effect1.43756870
55MP0006072_abnormal_retinal_apoptosis1.43672865
56MP0002019_abnormal_tumor_incidence1.43136188
57MP0004147_increased_porphyrin_level1.40747024
58MP0005174_abnormal_tail_pigmentation1.39219573
59MP0000313_abnormal_cell_death1.37839012
60MP0002837_dystrophic_cardiac_calcinosis1.37479941
61MP0005389_reproductive_system_phenotype1.36939597
62MP0008995_early_reproductive_senescence1.35128987
63MP0004145_abnormal_muscle_electrophysio1.33919173
64MP0004043_abnormal_pH_regulation1.32413179
65MP0003121_genomic_imprinting1.32016950
66MP0003567_abnormal_fetal_cardiomyocyte1.30018375
67MP0009046_muscle_twitch1.28833861
68MP0009697_abnormal_copulation1.28598648
69MP0001915_intracranial_hemorrhage1.28570640
70MP0002876_abnormal_thyroid_physiology1.27059561
71MP0009333_abnormal_splenocyte_physiolog1.23211704
72MP0002163_abnormal_gland_morphology1.22810120
73MP0005253_abnormal_eye_physiology1.22727406
74MP0001485_abnormal_pinna_reflex1.22143737
75MP0003705_abnormal_hypodermis_morpholog1.21035322
76MP0003763_abnormal_thymus_physiology1.18957217
77MP0002009_preneoplasia1.18877333
78MP0002095_abnormal_skin_pigmentation1.17652512
79MP0001873_stomach_inflammation1.16358692
80MP0002398_abnormal_bone_marrow1.14165359
81MP0002736_abnormal_nociception_after1.14133937
82MP0003941_abnormal_skin_development1.12374038
83MP0002928_abnormal_bile_duct1.12258144
84MP0003119_abnormal_digestive_system1.12090386
85MP0002722_abnormal_immune_system1.10967636
86MP0009745_abnormal_behavioral_response1.10812958
87MP0000703_abnormal_thymus_morphology1.10512389
88MP0000383_abnormal_hair_follicle1.09695275
89MP0001293_anophthalmia1.04320473
90MP0001919_abnormal_reproductive_system1.02526867
91MP0009672_abnormal_birth_weight1.02485864
92MP0000689_abnormal_spleen_morphology1.02401784
93MP0002210_abnormal_sex_determination1.00934760
94MP0003315_abnormal_perineum_morphology1.00670002
95MP0000647_abnormal_sebaceous_gland1.00041568
96MP0009053_abnormal_anal_canal0.99397627
97MP0009278_abnormal_bone_marrow0.99130563
98MP0003787_abnormal_imprinting0.99126310
99MP0001145_abnormal_male_reproductive0.98694259
100MP0002111_abnormal_tail_morphology0.97775390
101MP0002234_abnormal_pharynx_morphology0.92122953
102MP0004130_abnormal_muscle_cell0.91990351
103MP0001849_ear_inflammation0.91843591
104MP0005023_abnormal_wound_healing0.91646616
105MP0002877_abnormal_melanocyte_morpholog0.90852383
106MP0003566_abnormal_cell_adhesion0.90127333
107MP0003698_abnormal_male_reproductive0.89354895
108MP0004264_abnormal_extraembryonic_tissu0.89112420
109MP0002272_abnormal_nervous_system0.88238993
110MP0004885_abnormal_endolymph0.87539252
111MP0006035_abnormal_mitochondrial_morpho0.87363215
112MP0005266_abnormal_metabolism0.87093698
113MP0005646_abnormal_pituitary_gland0.86948231
114MP0005187_abnormal_penis_morphology0.86832572
115MP0002429_abnormal_blood_cell0.86829046
116MP0010030_abnormal_orbit_morphology0.86108579
117MP0000858_altered_metastatic_potential0.85697945
118MP0000428_abnormal_craniofacial_morphol0.85541796
119MP0005195_abnormal_posterior_eye0.85376091
120MP0002735_abnormal_chemical_nociception0.85257592
121MP0002751_abnormal_autonomic_nervous0.84397502
122MP0005423_abnormal_somatic_nervous0.84239942
123MP0005621_abnormal_cell_physiology0.82033048
124MP0001529_abnormal_vocalization0.81936250
125MP0005075_abnormal_melanosome_morpholog0.81737598
126MP0009703_decreased_birth_body0.81214112
127MP0000049_abnormal_middle_ear0.80457140
128MP0003937_abnormal_limbs/digits/tail_de0.78682897
129MP0000653_abnormal_sex_gland0.78671896
130MP0005384_cellular_phenotype0.77680954
131MP0001119_abnormal_female_reproductive0.76618657
132MP0005391_vision/eye_phenotype0.75931221
133MP0001929_abnormal_gametogenesis0.75692832
134MP0000477_abnormal_intestine_morphology0.75011409
135MP0002132_abnormal_respiratory_system0.74792792
136MP0003935_abnormal_craniofacial_develop0.73715667
137MP0003936_abnormal_reproductive_system0.73085044
138MP0008961_abnormal_basal_metabolism0.72936221
139MP0000716_abnormal_immune_system0.72448251
140MP0004742_abnormal_vestibular_system0.72170391
141MP0000432_abnormal_head_morphology0.71951589
142MP0008875_abnormal_xenobiotic_pharmacok0.71910073
143MP0004924_abnormal_behavior0.71361950
144MP0005386_behavior/neurological_phenoty0.71361950
145MP0004133_heterotaxia0.71321430
146MP0002557_abnormal_social/conspecific_i0.71238902
147MP0001286_abnormal_eye_development0.69934588
148MP0003861_abnormal_nervous_system0.69524403
149MP0000685_abnormal_immune_system0.69389924
150MP0005379_endocrine/exocrine_gland_phen0.69301403
151MP0003943_abnormal_hepatobiliary_system0.68329126
152MP0006276_abnormal_autonomic_nervous0.68164076
153MP0008770_decreased_survivor_rate0.67323818
154MP0005084_abnormal_gallbladder_morpholo0.67244038
155MP0001800_abnormal_humoral_immune0.67175907
156MP0006054_spinal_hemorrhage0.66642475
157MP0000516_abnormal_urinary_system0.66271952
158MP0005367_renal/urinary_system_phenotyp0.66271952
159MP0003303_peritoneal_inflammation0.66019969
160MP0000778_abnormal_nervous_system0.65810136
161MP0002092_abnormal_eye_morphology0.63229397
162MP0002925_abnormal_cardiovascular_devel0.62472116
163MP0003755_abnormal_palate_morphology0.60787184
164MP0003938_abnormal_ear_development0.60461338
165MP0006292_abnormal_olfactory_placode0.60231059
166MP0000358_abnormal_cell_content/0.58199820
167MP0002405_respiratory_system_inflammati0.58138054
168MP0000733_abnormal_muscle_development0.57548037
169MP0002653_abnormal_ependyma_morphology0.56507534
170MP0002114_abnormal_axial_skeleton0.55322100
171MP0002452_abnormal_antigen_presenting0.54841227
172MP0005501_abnormal_skin_physiology0.54239086

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)4.44328919
2Pancreatic cysts (HP:0001737)4.28300324
3Chromosomal breakage induced by crosslinking agents (HP:0003221)4.16051072
4Abnormality of the labia minora (HP:0012880)4.01399656
5Sparse lateral eyebrow (HP:0005338)3.97052766
6Abnormality of midbrain morphology (HP:0002418)3.88118489
7Molar tooth sign on MRI (HP:0002419)3.88118489
8Birth length less than 3rd percentile (HP:0003561)3.84533305
9Ependymoma (HP:0002888)3.75983446
10Congenital stationary night blindness (HP:0007642)3.68317896
11True hermaphroditism (HP:0010459)3.67816850
12Abnormality of the preputium (HP:0100587)3.63283721
13Reticulocytopenia (HP:0001896)3.63218502
14Pancreatic fibrosis (HP:0100732)3.60896413
15Selective tooth agenesis (HP:0001592)3.52880409
16Patellar aplasia (HP:0006443)3.38520166
17Abnormality of pyruvate family amino acid metabolism (HP:0010915)3.22440813
18Abnormality of alanine metabolism (HP:0010916)3.22440813
19Hyperalaninemia (HP:0003348)3.22440813
20Nephronophthisis (HP:0000090)3.21619767
21Breast hypoplasia (HP:0003187)3.21291898
22Impulsivity (HP:0100710)3.21185970
23Agnosia (HP:0010524)3.14716501
24Medulloblastoma (HP:0002885)3.13506481
25Aplasia/Hypoplasia of the patella (HP:0006498)3.11442802
26Abnormality of chromosome stability (HP:0003220)3.07420318
27Colon cancer (HP:0003003)2.93030265
28Carpal bone hypoplasia (HP:0001498)2.91074097
29Meckel diverticulum (HP:0002245)2.87158403
30Neoplasm of the oral cavity (HP:0100649)2.85209332
31Absent radius (HP:0003974)2.82504848
32Ectopic kidney (HP:0000086)2.76225266
33Abnormality of the renal medulla (HP:0100957)2.75659360
34Abnormality of cells of the erythroid lineage (HP:0012130)2.74786717
35Aplasia/Hypoplasia of the uvula (HP:0010293)2.72748509
36Pendular nystagmus (HP:0012043)2.70071060
37Abnormality of the ileum (HP:0001549)2.69903214
38Oral leukoplakia (HP:0002745)2.69315006
39Absent thumb (HP:0009777)2.66949960
40Proximal placement of thumb (HP:0009623)2.62900543
41Aplasia involving forearm bones (HP:0009822)2.62408653
42Absent forearm bone (HP:0003953)2.62408653
43Deviation of the thumb (HP:0009603)2.62363544
44Chronic hepatic failure (HP:0100626)2.59368614
45Hyperventilation (HP:0002883)2.58601254
4611 pairs of ribs (HP:0000878)2.55856198
47Abnormality of the pons (HP:0007361)2.55428954
48Myelodysplasia (HP:0002863)2.55055230
49Basal cell carcinoma (HP:0002671)2.54568654
50Abnormality of the anterior horn cell (HP:0006802)2.51934209
51Degeneration of anterior horn cells (HP:0002398)2.51934209
52Progressive inability to walk (HP:0002505)2.50771784
53Abnormal number of erythroid precursors (HP:0012131)2.50295894
54Tubular atrophy (HP:0000092)2.49982109
55Abnormality of the renal cortex (HP:0011035)2.46383288
56Abnormality of the astrocytes (HP:0100707)2.45479991
57Astrocytoma (HP:0009592)2.45479991
58Sclerocornea (HP:0000647)2.41835390
59Hypoplasia of the pons (HP:0012110)2.40176721
60Prominent nose (HP:0000448)2.39360726
61Type II lissencephaly (HP:0007260)2.37202580
62Missing ribs (HP:0000921)2.37034918
63Rhabdomyosarcoma (HP:0002859)2.36891452
64Aplastic anemia (HP:0001915)2.35916188
65Inability to walk (HP:0002540)2.34526660
66Rough bone trabeculation (HP:0100670)2.33100549
67Fair hair (HP:0002286)2.31940587
68Atresia of the external auditory canal (HP:0000413)2.30629625
69Volvulus (HP:0002580)2.29703130
70Congenital, generalized hypertrichosis (HP:0004540)2.28966726
71Bone marrow hypocellularity (HP:0005528)2.27863737
72Abnormality of DNA repair (HP:0003254)2.27239652
73Abnormal number of incisors (HP:0011064)2.27067215
74Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.26681264
75Short 4th metacarpal (HP:0010044)2.26681264
76Cystic liver disease (HP:0006706)2.26392091
77Rib fusion (HP:0000902)2.25938326
78Attenuation of retinal blood vessels (HP:0007843)2.25729866
79Protruding tongue (HP:0010808)2.24534307
80Neoplasm of the pancreas (HP:0002894)2.23811025
81Amaurosis fugax (HP:0100576)2.22115294
82Duplicated collecting system (HP:0000081)2.21270381
83Facial hemangioma (HP:0000329)2.21255974
84Abnormal biliary tract physiology (HP:0012439)2.20580246
85Bile duct proliferation (HP:0001408)2.20580246
86Genetic anticipation (HP:0003743)2.18795508
87Chorioretinal atrophy (HP:0000533)2.18500205
88Premature graying of hair (HP:0002216)2.18464235
89Furrowed tongue (HP:0000221)2.17865288
90Small intestinal stenosis (HP:0012848)2.17653722
91Duodenal stenosis (HP:0100867)2.17653722
92Partial agenesis of the corpus callosum (HP:0001338)2.15888227
93Tracheoesophageal fistula (HP:0002575)2.15132912
94Aplasia/hypoplasia of the humerus (HP:0006507)2.14251628
95Supernumerary spleens (HP:0009799)2.14206638
96Large for gestational age (HP:0001520)2.13602364
97Cerebral hypomyelination (HP:0006808)2.13391291
98Increased nuchal translucency (HP:0010880)2.09924148
99Anencephaly (HP:0002323)2.09114735
100Premature ovarian failure (HP:0008209)2.08900569
101Abnormality of pyrimidine metabolism (HP:0004353)2.08870244
102Clumsiness (HP:0002312)2.08598784
103Cafe-au-lait spot (HP:0000957)2.07756613
104Abnormal drinking behavior (HP:0030082)2.04415619
105Polydipsia (HP:0001959)2.04415619
106Squamous cell carcinoma (HP:0002860)2.04020331
107Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.03592712
108Lissencephaly (HP:0001339)2.03286707
109Glioma (HP:0009733)2.02850637
110Small hand (HP:0200055)2.02656082
111Bilateral microphthalmos (HP:0007633)2.00827130
112Short thumb (HP:0009778)2.00433883
113Anal stenosis (HP:0002025)2.00250906
114Multiple enchondromatosis (HP:0005701)1.98943118
115Abnormality of the carotid arteries (HP:0005344)1.98257958
116Short humerus (HP:0005792)1.97893759
117Aplasia/Hypoplasia of the tongue (HP:0010295)1.97282844
118Horseshoe kidney (HP:0000085)1.94875391
119Male pseudohermaphroditism (HP:0000037)1.93484070
120Clubbing of toes (HP:0100760)1.93319800
121Thrombocytosis (HP:0001894)1.90339234
122Abnormal rod and cone electroretinograms (HP:0008323)1.90066220
123Gaze-evoked nystagmus (HP:0000640)1.90041063
124Abnormality of the duodenum (HP:0002246)1.89398530
125Sloping forehead (HP:0000340)1.89350528
126Broad palm (HP:0001169)1.88674038
127Cellular immunodeficiency (HP:0005374)1.86734784
128Abnormality of the renal collecting system (HP:0004742)1.86644314
129Neoplasm of the adrenal cortex (HP:0100641)1.86284889
130Dandy-Walker malformation (HP:0001305)1.85975444
131Preaxial hand polydactyly (HP:0001177)1.85788106
132Gastrointestinal atresia (HP:0002589)1.84694688
133Congenital hepatic fibrosis (HP:0002612)1.84251883
134Trismus (HP:0000211)1.84241902
135Neoplasm of striated muscle (HP:0009728)1.83311424
136Esophageal atresia (HP:0002032)1.82460867
137Pallor (HP:0000980)1.81046715
138Intestinal fistula (HP:0100819)1.80573487
139Medial flaring of the eyebrow (HP:0010747)1.80281210
140Acute myeloid leukemia (HP:0004808)1.80256520
141Intestinal atresia (HP:0011100)1.79584028
142Abnormality of the calcaneus (HP:0008364)1.78299635
143Progressive cerebellar ataxia (HP:0002073)1.78050436
144Spinal muscular atrophy (HP:0007269)1.77957401
145Shawl scrotum (HP:0000049)1.77907133
146Slender long bone (HP:0003100)1.76190781
147Aplasia/Hypoplasia of the tibia (HP:0005772)1.76120958
148Concave nail (HP:0001598)1.75497900
149Triphalangeal thumb (HP:0001199)1.75141156
150Abnormal lung lobation (HP:0002101)1.74928638
151Atrophy/Degeneration involving motor neurons (HP:0007373)1.73830608
152Ureteral duplication (HP:0000073)1.73783103
153Lymphoma (HP:0002665)1.73648947
154Aplasia/hypoplasia of the uterus (HP:0008684)1.73377333
155Abolished electroretinogram (ERG) (HP:0000550)1.73013078
156Cutaneous melanoma (HP:0012056)1.72730872
157Secondary amenorrhea (HP:0000869)1.72687794
158Vertebral clefting (HP:0008428)1.72259766
159Keratoconus (HP:0000563)1.71685319
160Increased corneal curvature (HP:0100692)1.71685319
161Biliary tract neoplasm (HP:0100574)1.71562836
162Broad-based gait (HP:0002136)1.71388482
163Increased CSF lactate (HP:0002490)1.70982667
164Severe muscular hypotonia (HP:0006829)1.70793134
165Generalized hypopigmentation of hair (HP:0011358)1.68867438
166Tachypnea (HP:0002789)1.67847555
167Microretrognathia (HP:0000308)1.66985524
168Decreased electroretinogram (ERG) amplitude (HP:0000654)1.66879630
169Oligodactyly (hands) (HP:0001180)1.65726370
170Postaxial foot polydactyly (HP:0001830)1.64831115
171Oculomotor apraxia (HP:0000657)1.63593075
172Abnormality of homocysteine metabolism (HP:0010919)1.62346864
173Homocystinuria (HP:0002156)1.62346864

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK4.34431880
2WEE13.98841643
3CDC73.78387927
4BUB13.78386135
5CDK123.47172817
6BMPR1B3.20950776
7NEK22.66116727
8NUAK12.60827158
9WNK42.41233850
10TSSK62.38890046
11EEF2K2.37497680
12EPHA22.30542693
13TTK2.22491220
14ADRBK22.12231901
15SRPK12.11426214
16EIF2AK11.93687268
17ACVR1B1.92802029
18MKNK21.91392246
19NME21.86594762
20CDK71.85196945
21ATR1.83735126
22TAF11.83365366
23MKNK11.81810915
24NEK11.77707587
25WNK31.76431558
26GRK11.76195550
27PNCK1.75708923
28RPS6KB21.73226493
29PLK11.71313491
30TNIK1.70543611
31MAP3K81.64603275
32CDK41.60470291
33MAP4K21.59956242
34PLK41.56884726
35PKN21.55493746
36INSRR1.54439407
37AURKB1.54256542
38ALK1.53727385
39STK391.53416797
40LATS21.52681860
41CHEK11.51818545
42BRSK21.50770046
43SCYL21.49118459
44CHEK21.48316369
45LATS11.42985254
46STK101.39378823
47MAP4K11.38493497
48PASK1.38183768
49PLK31.34551884
50MAP3K101.27303928
51CASK1.26658779
52MAPK131.23480465
53CAMK1D1.20437967
54TLK11.20087668
55DYRK31.18253668
56TAOK21.15353420
57MAP3K41.14559564
58CAMKK21.14430679
59MUSK1.12843988
60ATM1.10648631
61PIM11.10172840
62FLT31.10027031
63STK31.09817921
64MAP2K61.08022312
65STK38L1.06251928
66NLK1.05980563
67RPS6KA41.05018707
68OXSR11.04438740
69STK41.03959447
70EIF2AK31.03485940
71CDK21.03344084
72TESK21.01451800
73VRK10.96772883
74CAMK1G0.96365219
75MAPKAPK50.95833613
76AURKA0.93776497
77BRD40.93475078
78VRK20.91681880
79MAPK150.90104613
80MTOR0.89614901
81PAK40.88195811
82TAOK30.85381440
83GRK60.85101914
84ZAK0.82919402
85TRIM280.81605331
86ADRBK10.79247897
87CDK60.78642595
88TGFBR10.77643188
89TRIB30.75495996
90BRSK10.72798545
91MAPKAPK30.71488063
92PINK10.70640872
93CDK10.69689007
94TXK0.69539080
95NME10.66233909
96JAK30.66204384
97CSNK2A20.65900417
98MAP2K30.63896852
99SIK20.62130468
100DYRK20.60992785
101CLK10.60664278
102CSNK1G10.60475394
103AKT30.58477363
104PRKCG0.57904863
105STK110.56531907
106MAP3K110.55923754
107MELK0.55399036
108CSNK1E0.55212969
109AKT20.54716478
110PAK30.54299902
111WNK10.53200871
112FGFR10.52101092
113STK160.50473959
114PIK3CA0.48437068
115IRAK10.48388019
116DAPK20.47733192
117PAK10.46745112
118PRKAA10.46017226
119CSNK1D0.45692380
120PIM20.45517368
121CSNK1A1L0.44903573
122CSNK2A10.44102782
123LRRK20.43477951
124PLK20.42577857
125CHUK0.42419506
126CSNK1G20.41828612
127MAP3K50.41061066
128ZAP700.40532769
129PHKG20.40180100
130PHKG10.40180100
131PRKDC0.40087151
132TEC0.39666440
133PBK0.39461181
134PRKCI0.39398216
135MAPK140.38387493
136PRKCQ0.37853978
137PRKCE0.37403086
138EIF2AK20.36067301
139PAK20.35187135
140PKN10.35118328
141CAMK40.34863482
142CSNK1G30.33803002
143FGFR20.33688640
144RPS6KA50.31706097
145OBSCN0.30356544
146PRKAA20.29524696
147AKT10.29353034
148RAF10.28059632
149CSF1R0.27733134
150MAPK10.26258087
151ERBB40.26223683
152RPS6KB10.26198201
153MAP3K30.25954165
154BTK0.25669910
155GSK3B0.25560676
156RPS6KC10.25101315
157RPS6KL10.25101315

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.43438546
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.36690534
3Mismatch repair_Homo sapiens_hsa034303.92209121
4RNA transport_Homo sapiens_hsa030133.39309831
5Spliceosome_Homo sapiens_hsa030403.31001978
6One carbon pool by folate_Homo sapiens_hsa006703.17971369
7RNA polymerase_Homo sapiens_hsa030203.03066019
8Base excision repair_Homo sapiens_hsa034102.70645959
9Cell cycle_Homo sapiens_hsa041102.69218219
10Non-homologous end-joining_Homo sapiens_hsa034502.67789377
11Homologous recombination_Homo sapiens_hsa034402.61750703
12Nitrogen metabolism_Homo sapiens_hsa009102.39319830
13Ribosome_Homo sapiens_hsa030102.38733564
14Nucleotide excision repair_Homo sapiens_hsa034202.37519131
15Fanconi anemia pathway_Homo sapiens_hsa034602.35747706
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.32999901
17Phototransduction_Homo sapiens_hsa047442.24502303
18Linoleic acid metabolism_Homo sapiens_hsa005912.08960958
19alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.06927526
20Pyrimidine metabolism_Homo sapiens_hsa002402.05585723
21Proteasome_Homo sapiens_hsa030502.04144419
22mRNA surveillance pathway_Homo sapiens_hsa030152.02757586
23p53 signaling pathway_Homo sapiens_hsa041151.98972124
24Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.98037804
25RNA degradation_Homo sapiens_hsa030181.95007917
26Basal transcription factors_Homo sapiens_hsa030221.54050293
27Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.50651724
28Ether lipid metabolism_Homo sapiens_hsa005651.46098808
29Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.43739016
30Butanoate metabolism_Homo sapiens_hsa006501.43573521
31Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.37566567
32Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.27325619
33Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.27032110
34Oxidative phosphorylation_Homo sapiens_hsa001901.22215300
35Systemic lupus erythematosus_Homo sapiens_hsa053221.19879645
36Maturity onset diabetes of the young_Homo sapiens_hsa049501.19452798
37Epstein-Barr virus infection_Homo sapiens_hsa051691.17044232
38Olfactory transduction_Homo sapiens_hsa047401.14987492
39Antigen processing and presentation_Homo sapiens_hsa046121.13271251
40Herpes simplex infection_Homo sapiens_hsa051681.11936596
41Nicotine addiction_Homo sapiens_hsa050331.11288890
42Cyanoamino acid metabolism_Homo sapiens_hsa004601.09195451
43Protein export_Homo sapiens_hsa030601.07426117
44Caffeine metabolism_Homo sapiens_hsa002321.06371409
45Viral carcinogenesis_Homo sapiens_hsa052031.06076704
46Parkinsons disease_Homo sapiens_hsa050121.05601773
47Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.05244623
48Biosynthesis of amino acids_Homo sapiens_hsa012301.03923777
49Thyroid cancer_Homo sapiens_hsa052161.03876978
50Vitamin B6 metabolism_Homo sapiens_hsa007501.00182303
51Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.99393983
52Purine metabolism_Homo sapiens_hsa002300.98229525
53Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.95164407
54MicroRNAs in cancer_Homo sapiens_hsa052060.93242210
55Pentose phosphate pathway_Homo sapiens_hsa000300.93091623
56Huntingtons disease_Homo sapiens_hsa050160.92262951
57Selenocompound metabolism_Homo sapiens_hsa004500.88618165
58Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.87874627
59HTLV-I infection_Homo sapiens_hsa051660.87648020
60Cysteine and methionine metabolism_Homo sapiens_hsa002700.86330486
61Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.85242154
62Tryptophan metabolism_Homo sapiens_hsa003800.84633147
63Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.84589675
64Taste transduction_Homo sapiens_hsa047420.84005520
65Small cell lung cancer_Homo sapiens_hsa052220.82744714
66Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.78232853
67Primary immunodeficiency_Homo sapiens_hsa053400.77604540
68Propanoate metabolism_Homo sapiens_hsa006400.77205327
69Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.77018514
70Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.74664356
71Oocyte meiosis_Homo sapiens_hsa041140.73738263
72Transcriptional misregulation in cancer_Homo sapiens_hsa052020.71916094
73Folate biosynthesis_Homo sapiens_hsa007900.70928685
74Morphine addiction_Homo sapiens_hsa050320.68715621
75Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.67143079
76NF-kappa B signaling pathway_Homo sapiens_hsa040640.66536762
77Drug metabolism - other enzymes_Homo sapiens_hsa009830.66072878
78Hedgehog signaling pathway_Homo sapiens_hsa043400.65858355
79Regulation of autophagy_Homo sapiens_hsa041400.64667365
80ABC transporters_Homo sapiens_hsa020100.62105960
81Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.61602890
82Legionellosis_Homo sapiens_hsa051340.60765758
83Dorso-ventral axis formation_Homo sapiens_hsa043200.58481259
84Apoptosis_Homo sapiens_hsa042100.57193590
85Notch signaling pathway_Homo sapiens_hsa043300.55041451
86Sulfur relay system_Homo sapiens_hsa041220.53084061
87TGF-beta signaling pathway_Homo sapiens_hsa043500.52582152
88Hippo signaling pathway_Homo sapiens_hsa043900.52488757
89Colorectal cancer_Homo sapiens_hsa052100.51541947
90Viral myocarditis_Homo sapiens_hsa054160.51324760
91Central carbon metabolism in cancer_Homo sapiens_hsa052300.51008340
92Chronic myeloid leukemia_Homo sapiens_hsa052200.50634848
93Alzheimers disease_Homo sapiens_hsa050100.50065254
94Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.49042745
95Acute myeloid leukemia_Homo sapiens_hsa052210.48664719
96Measles_Homo sapiens_hsa051620.48661609
97Cardiac muscle contraction_Homo sapiens_hsa042600.48555732
98Hepatitis B_Homo sapiens_hsa051610.48488795
99Bladder cancer_Homo sapiens_hsa052190.47845658
100Ovarian steroidogenesis_Homo sapiens_hsa049130.46427023
101Lysine degradation_Homo sapiens_hsa003100.45982929
102Calcium signaling pathway_Homo sapiens_hsa040200.44811696
103Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.44355554
104mTOR signaling pathway_Homo sapiens_hsa041500.43448583
105N-Glycan biosynthesis_Homo sapiens_hsa005100.42892836
106Serotonergic synapse_Homo sapiens_hsa047260.41433509
1072-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.41371579
108Steroid biosynthesis_Homo sapiens_hsa001000.41326122
109Basal cell carcinoma_Homo sapiens_hsa052170.40440412
110Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.39745818
111Melanoma_Homo sapiens_hsa052180.39269593
112Metabolic pathways_Homo sapiens_hsa011000.39097352
113Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.37621050
114HIF-1 signaling pathway_Homo sapiens_hsa040660.37315833
115Circadian rhythm_Homo sapiens_hsa047100.35777587
116Peroxisome_Homo sapiens_hsa041460.35471432
117Intestinal immune network for IgA production_Homo sapiens_hsa046720.35349148
118Glutamatergic synapse_Homo sapiens_hsa047240.34712016
119Influenza A_Homo sapiens_hsa051640.34071187
120Pathways in cancer_Homo sapiens_hsa052000.33403974
121Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.33326648
122Arachidonic acid metabolism_Homo sapiens_hsa005900.32979887
123Vitamin digestion and absorption_Homo sapiens_hsa049770.32090767
124Non-small cell lung cancer_Homo sapiens_hsa052230.30729373
125Wnt signaling pathway_Homo sapiens_hsa043100.30727151
126Insulin secretion_Homo sapiens_hsa049110.30448060
127beta-Alanine metabolism_Homo sapiens_hsa004100.30327566
128Carbon metabolism_Homo sapiens_hsa012000.30150518
129Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.29705627
130Fatty acid biosynthesis_Homo sapiens_hsa000610.29644075
131Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.29524591
132Adherens junction_Homo sapiens_hsa045200.28449895
133Prostate cancer_Homo sapiens_hsa052150.28030256
134Long-term depression_Homo sapiens_hsa047300.27222042
135Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.26235392
136Glycerolipid metabolism_Homo sapiens_hsa005610.25959141
137Circadian entrainment_Homo sapiens_hsa047130.25438339
138Sulfur metabolism_Homo sapiens_hsa009200.24921759
139Thyroid hormone signaling pathway_Homo sapiens_hsa049190.24535766
140Jak-STAT signaling pathway_Homo sapiens_hsa046300.23758487
141Fructose and mannose metabolism_Homo sapiens_hsa000510.23547130
142B cell receptor signaling pathway_Homo sapiens_hsa046620.23507852
143T cell receptor signaling pathway_Homo sapiens_hsa046600.22942415
144Chemical carcinogenesis_Homo sapiens_hsa052040.22753753
145Pancreatic cancer_Homo sapiens_hsa052120.22339160
146Proteoglycans in cancer_Homo sapiens_hsa052050.22235837
147Alcoholism_Homo sapiens_hsa050340.21913627
148Galactose metabolism_Homo sapiens_hsa000520.20997552
149NOD-like receptor signaling pathway_Homo sapiens_hsa046210.20216931
150Shigellosis_Homo sapiens_hsa051310.20096483
151RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.19331677
152Hematopoietic cell lineage_Homo sapiens_hsa046400.19227950
153Glutathione metabolism_Homo sapiens_hsa004800.18724500
154Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.18151877
155FoxO signaling pathway_Homo sapiens_hsa040680.16255822

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