NOP56P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)6.11051088
2maturation of SSU-rRNA (GO:0030490)5.36417313
3viral transcription (GO:0019083)5.24994370
4translational termination (GO:0006415)5.04339251
5ribosomal small subunit biogenesis (GO:0042274)4.98451301
6ATP synthesis coupled proton transport (GO:0015986)4.83397306
7energy coupled proton transport, down electrochemical gradient (GO:0015985)4.83397306
8mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.69220661
9behavioral response to nicotine (GO:0035095)4.46535565
10SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.34122572
11translational elongation (GO:0006414)4.29385251
12cotranslational protein targeting to membrane (GO:0006613)4.29374459
13ribosomal large subunit biogenesis (GO:0042273)4.28000253
14protein targeting to ER (GO:0045047)4.26753447
15cornea development in camera-type eye (GO:0061303)4.21025093
16peptidyl-histidine modification (GO:0018202)4.16341159
17protein neddylation (GO:0045116)4.15755781
18regulation of nuclear cell cycle DNA replication (GO:0033262)4.13568995
19establishment of protein localization to endoplasmic reticulum (GO:0072599)4.05814054
20protein localization to endoplasmic reticulum (GO:0070972)4.03096726
21adaptation of signaling pathway (GO:0023058)3.96028083
22establishment of protein localization to mitochondrial membrane (GO:0090151)3.92772198
23viral life cycle (GO:0019058)3.84028091
24cellular protein complex disassembly (GO:0043624)3.81207026
25nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.56786274
26translational initiation (GO:0006413)3.52337047
27arginine catabolic process (GO:0006527)3.46547303
28CTP biosynthetic process (GO:0006241)3.45811615
29CTP metabolic process (GO:0046036)3.45811615
30nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.40627922
31positive regulation of sodium ion transmembrane transport (GO:1902307)3.40098176
32protein complex disassembly (GO:0043241)3.28067894
33somite development (GO:0061053)3.27845418
34mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.26702377
35exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.25105511
36chaperone-mediated protein transport (GO:0072321)3.22866269
37RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.22042190
38tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.22042190
39cytochrome complex assembly (GO:0017004)3.19251198
40pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.16922244
41respiratory chain complex IV assembly (GO:0008535)3.16001257
42GTP biosynthetic process (GO:0006183)3.14542502
43pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.12912630
44macromolecular complex disassembly (GO:0032984)3.12702274
45translation (GO:0006412)3.08022800
46pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.07910369
47pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.06555298
48protein complex biogenesis (GO:0070271)3.06190265
49respiratory electron transport chain (GO:0022904)3.04403213
50negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)3.03774315
51mitochondrion transport along microtubule (GO:0047497)3.03755037
52establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.03755037
53cardiovascular system development (GO:0072358)3.03274782
54electron transport chain (GO:0022900)3.02813831
55regulation of mitochondrial translation (GO:0070129)3.01598734
56neuron fate determination (GO:0048664)3.01536044
57synapsis (GO:0007129)2.99952618
58pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.96389210
59establishment of mitochondrion localization (GO:0051654)2.96049343
60arginine metabolic process (GO:0006525)2.95019722
61water-soluble vitamin biosynthetic process (GO:0042364)2.94111981
62DNA deamination (GO:0045006)2.92690054
63ribonucleoprotein complex biogenesis (GO:0022613)2.92489712
64cellular component biogenesis (GO:0044085)2.92330731
65synaptic transmission, cholinergic (GO:0007271)2.89262364
66L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.87832526
67regulation of cilium movement (GO:0003352)2.86622639
68nuclear-transcribed mRNA catabolic process (GO:0000956)2.86576446
69chromatin remodeling at centromere (GO:0031055)2.84837979
70ribonucleoside triphosphate biosynthetic process (GO:0009201)2.81743070
71protein K6-linked ubiquitination (GO:0085020)2.81105442
72purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.80682532
73protein targeting to membrane (GO:0006612)2.75762745
74mitochondrial respiratory chain complex assembly (GO:0033108)2.75202533
75purine nucleoside triphosphate biosynthetic process (GO:0009145)2.74478875
76positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.74426039
77protein polyglutamylation (GO:0018095)2.74409871
78fucose catabolic process (GO:0019317)2.74065451
79L-fucose metabolic process (GO:0042354)2.74065451
80L-fucose catabolic process (GO:0042355)2.74065451
81termination of RNA polymerase III transcription (GO:0006386)2.73725608
82transcription elongation from RNA polymerase III promoter (GO:0006385)2.73725608
83pyrimidine nucleotide catabolic process (GO:0006244)2.72662933
84ATP biosynthetic process (GO:0006754)2.69989910
85negative regulation of DNA-templated transcription, elongation (GO:0032785)2.68760200
86signal peptide processing (GO:0006465)2.68516932
87mRNA catabolic process (GO:0006402)2.68205640
88short-term memory (GO:0007614)2.68014751
89regulation of microtubule-based movement (GO:0060632)2.67369257
90opioid receptor signaling pathway (GO:0038003)2.64765133
91mitochondrial respiratory chain complex I assembly (GO:0032981)2.63477565
92NADH dehydrogenase complex assembly (GO:0010257)2.63477565
93mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.63477565
94seminiferous tubule development (GO:0072520)2.63308271
95UTP biosynthetic process (GO:0006228)2.62592918
96neuron recognition (GO:0008038)2.60444010
97rRNA processing (GO:0006364)2.58004226
98substrate-independent telencephalic tangential migration (GO:0021826)2.57863106
99substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.57863106
100DNA replication checkpoint (GO:0000076)2.52347348

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.87481155
2ZNF274_21170338_ChIP-Seq_K562_Hela3.24242388
3E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.23447331
4MYCN_21190229_ChIP-Seq_SHEP-21N_Human3.08075501
5GABP_17652178_ChIP-ChIP_JURKAT_Human2.90040927
6HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.78444473
7EST1_17652178_ChIP-ChIP_JURKAT_Human2.78016109
8KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.64336415
9TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.56340182
10NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.33601063
11E2F7_22180533_ChIP-Seq_HELA_Human2.22597350
12ETS1_20019798_ChIP-Seq_JURKAT_Human2.19082557
13JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.01536068
14VDR_22108803_ChIP-Seq_LS180_Human1.94484686
15MYC_18940864_ChIP-ChIP_HL60_Human1.94434974
16CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.87880937
17SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.86552897
18ELF1_17652178_ChIP-ChIP_JURKAT_Human1.81415438
19CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.79407521
20MYC_18555785_ChIP-Seq_MESCs_Mouse1.78638093
21CTBP1_25329375_ChIP-Seq_LNCAP_Human1.74869872
22IRF1_19129219_ChIP-ChIP_H3396_Human1.69469921
23REST_21632747_ChIP-Seq_MESCs_Mouse1.68944964
24CBX2_27304074_Chip-Seq_ESCs_Mouse1.65755601
25TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.64987200
26EZH2_27304074_Chip-Seq_ESCs_Mouse1.62841702
27JARID2_20064375_ChIP-Seq_MESCs_Mouse1.58751997
28GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.54944332
29BMI1_23680149_ChIP-Seq_NPCS_Mouse1.53524279
30IGF1R_20145208_ChIP-Seq_DFB_Human1.53243363
31FUS_26573619_Chip-Seq_HEK293_Human1.52789017
32FOXP3_21729870_ChIP-Seq_TREG_Human1.50295558
33PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.45003890
34MYC_18358816_ChIP-ChIP_MESCs_Mouse1.42356270
35GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.42009000
36RNF2_27304074_Chip-Seq_NSC_Mouse1.37548016
37E2F4_17652178_ChIP-ChIP_JURKAT_Human1.37394687
38SRF_21415370_ChIP-Seq_HL-1_Mouse1.33892440
39HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.32956113
40NOTCH1_21737748_ChIP-Seq_TLL_Human1.31809584
41CTBP2_25329375_ChIP-Seq_LNCAP_Human1.30755616
42TTF2_22483619_ChIP-Seq_HELA_Human1.30296492
43SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.30010591
44SUZ12_27294783_Chip-Seq_ESCs_Mouse1.28711017
45TP53_22573176_ChIP-Seq_HFKS_Human1.27465207
46VDR_23849224_ChIP-Seq_CD4+_Human1.26884698
47GBX2_23144817_ChIP-Seq_PC3_Human1.26226110
48ZFP57_27257070_Chip-Seq_ESCs_Mouse1.25678508
49SOX2_18555785_ChIP-Seq_MESCs_Mouse1.25567618
50EWS_26573619_Chip-Seq_HEK293_Human1.22979748
51EZH2_27294783_Chip-Seq_ESCs_Mouse1.22506204
52CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.21914448
53CREB1_15753290_ChIP-ChIP_HEK293T_Human1.20948953
54REST_18959480_ChIP-ChIP_MESCs_Mouse1.20233933
55EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.20155124
56THAP11_20581084_ChIP-Seq_MESCs_Mouse1.19394075
57ELK1_19687146_ChIP-ChIP_HELA_Human1.17109869
58AR_21572438_ChIP-Seq_LNCaP_Human1.16540551
59ERA_21632823_ChIP-Seq_H3396_Human1.15782340
60YY1_21170310_ChIP-Seq_MESCs_Mouse1.14388714
61KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.14295404
62ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.12424254
63POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.12107974
64EED_16625203_ChIP-ChIP_MESCs_Mouse1.11259361
65GABP_19822575_ChIP-Seq_HepG2_Human1.11127167
66RNF2_27304074_Chip-Seq_ESCs_Mouse1.11014864
67MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.10408051
68RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.09708406
69XRN2_22483619_ChIP-Seq_HELA_Human1.08671617
70HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.08134609
71SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.07695055
72NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.02736906
73IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.01048114
74CBP_20019798_ChIP-Seq_JUKART_Human1.01048114
75SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.99733277
76P300_19829295_ChIP-Seq_ESCs_Human0.98125250
77CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.98085675
78TAF15_26573619_Chip-Seq_HEK293_Human0.94038421
79SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.93346466
80MYC_19079543_ChIP-ChIP_MESCs_Mouse0.93262319
81MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.91582032
82SOX2_16153702_ChIP-ChIP_HESCs_Human0.90781629
83RNF2_18974828_ChIP-Seq_MESCs_Mouse0.89321077
84EZH2_18974828_ChIP-Seq_MESCs_Mouse0.89321077
85POU5F1_16153702_ChIP-ChIP_HESCs_Human0.89283944
86PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.88798439
87KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.88567232
88JARID2_20075857_ChIP-Seq_MESCs_Mouse0.88301548
89NANOG_20526341_ChIP-Seq_ESCs_Human0.87749074
90SALL1_21062744_ChIP-ChIP_HESCs_Human0.87035753
91SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.85314575
92ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.84962684
93HOXB7_26014856_ChIP-Seq_BT474_Human0.84714129
94SMAD3_21741376_ChIP-Seq_ESCs_Human0.83307381
95ETV2_25802403_ChIP-Seq_MESCs_Mouse0.83165505
96AR_25329375_ChIP-Seq_VCAP_Human0.82866557
97CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.82674595
98CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.82650941
99FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.82434021
100MYC_19030024_ChIP-ChIP_MESCs_Mouse0.82296944

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation5.60564595
2MP0003646_muscle_fatigue4.08455004
3MP0006292_abnormal_olfactory_placode3.94942779
4MP0000566_synostosis3.15122113
5MP0002234_abnormal_pharynx_morphology3.05182676
6MP0008789_abnormal_olfactory_epithelium2.70919046
7MP0003122_maternal_imprinting2.42003691
8MP0005499_abnormal_olfactory_system2.39485601
9MP0005394_taste/olfaction_phenotype2.39485601
10MP0003787_abnormal_imprinting2.37736161
11MP0003121_genomic_imprinting2.28219533
12MP0008877_abnormal_DNA_methylation2.16859792
13MP0008058_abnormal_DNA_repair2.09966040
14MP0002837_dystrophic_cardiac_calcinosis2.05182342
15MP0002736_abnormal_nociception_after1.89563782
16MP0005360_urolithiasis1.88192910
17MP0004043_abnormal_pH_regulation1.88076483
18MP0001293_anophthalmia1.86661464
19MP0001968_abnormal_touch/_nociception1.85382665
20MP0005645_abnormal_hypothalamus_physiol1.69854915
21MP0000049_abnormal_middle_ear1.67405448
22MP0004133_heterotaxia1.64174896
23MP0003283_abnormal_digestive_organ1.62716849
24MP0006072_abnormal_retinal_apoptosis1.62243222
25MP0000778_abnormal_nervous_system1.60793061
26MP0001440_abnormal_grooming_behavior1.49000799
27MP0004885_abnormal_endolymph1.48589131
28MP0001529_abnormal_vocalization1.48355922
29MP0004145_abnormal_muscle_electrophysio1.48141475
30MP0009053_abnormal_anal_canal1.48049096
31MP0008872_abnormal_physiological_respon1.46066133
32MP0002938_white_spotting1.44890252
33MP0002272_abnormal_nervous_system1.42445852
34MP0003880_abnormal_central_pattern1.40743306
35MP0009745_abnormal_behavioral_response1.38722533
36MP0005423_abnormal_somatic_nervous1.35390771
37MP0000631_abnormal_neuroendocrine_gland1.34050368
38MP0002102_abnormal_ear_morphology1.32640449
39MP0003937_abnormal_limbs/digits/tail_de1.32054242
40MP0002233_abnormal_nose_morphology1.30590694
41MP0005551_abnormal_eye_electrophysiolog1.28777247
42MP0001986_abnormal_taste_sensitivity1.28159993
43MP0001905_abnormal_dopamine_level1.27208220
44MP0002735_abnormal_chemical_nociception1.23882774
45MP0010030_abnormal_orbit_morphology1.23229524
46MP0003123_paternal_imprinting1.21336572
47MP0003718_maternal_effect1.19683886
48MP0002733_abnormal_thermal_nociception1.19537511
49MP0002653_abnormal_ependyma_morphology1.16863164
50MP0003693_abnormal_embryo_hatching1.15451966
51MP0004142_abnormal_muscle_tone1.15156851
52MP0004859_abnormal_synaptic_plasticity1.14256635
53MP0001919_abnormal_reproductive_system1.13442238
54MP0002557_abnormal_social/conspecific_i1.13333541
55MP0000955_abnormal_spinal_cord1.13156341
56MP0003890_abnormal_embryonic-extraembry1.12024629
57MP0006276_abnormal_autonomic_nervous1.11636936
58MP0001970_abnormal_pain_threshold1.10877808
59MP0003635_abnormal_synaptic_transmissio1.09184271
60MP0005195_abnormal_posterior_eye1.07134593
61MP0002063_abnormal_learning/memory/cond1.07049158
62MP0003938_abnormal_ear_development1.06631876
63MP0002752_abnormal_somatic_nervous1.03771739
64MP0008775_abnormal_heart_ventricle1.03386242
65MP0002572_abnormal_emotion/affect_behav1.01292913
66MP0002184_abnormal_innervation1.01219686
67MP0003186_abnormal_redox_activity0.99556439
68MP0005377_hearing/vestibular/ear_phenot0.98066188
69MP0003878_abnormal_ear_physiology0.98066188
70MP0001485_abnormal_pinna_reflex0.96741981
71MP0004742_abnormal_vestibular_system0.93361760
72MP0002163_abnormal_gland_morphology0.93209564
73MP0003119_abnormal_digestive_system0.92910976
74MP0002638_abnormal_pupillary_reflex0.92198092
75MP0002210_abnormal_sex_determination0.91903182
76MP0001984_abnormal_olfaction0.91123996
77MP0004858_abnormal_nervous_system0.90882809
78MP0001286_abnormal_eye_development0.90640717
79MP0001486_abnormal_startle_reflex0.89895490
80MP0005084_abnormal_gallbladder_morpholo0.87006468
81MP0000569_abnormal_digit_pigmentation0.84354752
82MP0002095_abnormal_skin_pigmentation0.79312865
83MP0002116_abnormal_craniofacial_bone0.77939923
84MP0002109_abnormal_limb_morphology0.77291263
85MP0003942_abnormal_urinary_system0.77289772
86MP0009046_muscle_twitch0.76964972
87MP0002734_abnormal_mechanical_nocicepti0.76903907
88MP0005389_reproductive_system_phenotype0.76369572
89MP0000026_abnormal_inner_ear0.75747141
90MP0001324_abnormal_eye_pigmentation0.75056856
91MP0002067_abnormal_sensory_capabilities0.74403892
92MP0010094_abnormal_chromosome_stability0.74182359
93MP0005386_behavior/neurological_phenoty0.73019023
94MP0004924_abnormal_behavior0.73019023
95MP0004811_abnormal_neuron_physiology0.72827364
96MP0002882_abnormal_neuron_morphology0.72626232
97MP0003861_abnormal_nervous_system0.72360533
98MP0000427_abnormal_hair_cycle0.71866001
99MP0002064_seizures0.70368518
100MP0002152_abnormal_brain_morphology0.69691521

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)4.55488322
2Absent rod-and cone-mediated responses on ERG (HP:0007688)3.86740175
3Acute necrotizing encephalopathy (HP:0006965)3.53468016
4Pendular nystagmus (HP:0012043)3.47709506
5Abnormality of cells of the erythroid lineage (HP:0012130)3.41201462
6Pancreatic fibrosis (HP:0100732)3.28185076
7Abnormal rod and cone electroretinograms (HP:0008323)3.20175550
8Pancreatic cysts (HP:0001737)3.12922854
9Nephronophthisis (HP:0000090)3.09980635
10Acute encephalopathy (HP:0006846)3.02906112
11Abnormal mitochondria in muscle tissue (HP:0008316)3.01700647
12Absent thumb (HP:0009777)2.99170113
13Macrocytic anemia (HP:0001972)2.89154911
14Mitochondrial inheritance (HP:0001427)2.89105682
15Colon cancer (HP:0003003)2.87819763
16Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.86708138
17Abnormality of alanine metabolism (HP:0010916)2.86708138
18Hyperalaninemia (HP:0003348)2.86708138
19Aplasia/Hypoplasia of the sacrum (HP:0008517)2.85231561
20Septo-optic dysplasia (HP:0100842)2.80664657
21Increased CSF lactate (HP:0002490)2.79272483
22Progressive macrocephaly (HP:0004481)2.78956895
23True hermaphroditism (HP:0010459)2.73801231
24Abnormality of the labia minora (HP:0012880)2.68726737
25Hyperglycinemia (HP:0002154)2.65100875
26Ectopic kidney (HP:0000086)2.62976599
27Pallor (HP:0000980)2.61645707
28Cerebral hypomyelination (HP:0006808)2.59634829
29Abnormal number of erythroid precursors (HP:0012131)2.58403608
303-Methylglutaconic aciduria (HP:0003535)2.50893175
31Medial flaring of the eyebrow (HP:0010747)2.48999363
32Hepatocellular necrosis (HP:0001404)2.48839220
33Sclerocornea (HP:0000647)2.48425661
34Hepatic necrosis (HP:0002605)2.47538527
35Molar tooth sign on MRI (HP:0002419)2.44394795
36Abnormality of midbrain morphology (HP:0002418)2.44394795
37Abnormality of the renal medulla (HP:0100957)2.41472465
38Limb dystonia (HP:0002451)2.37182255
39Increased corneal curvature (HP:0100692)2.36277900
40Keratoconus (HP:0000563)2.36277900
41Aplasia/Hypoplasia of the uvula (HP:0010293)2.32671784
42Pachygyria (HP:0001302)2.27064731
43Lissencephaly (HP:0001339)2.25776044
44Rib fusion (HP:0000902)2.24422671
45Maternal diabetes (HP:0009800)2.21783565
46Increased hepatocellular lipid droplets (HP:0006565)2.21492072
47Chromsome breakage (HP:0040012)2.19733371
48Cerebral edema (HP:0002181)2.19305854
49Lipid accumulation in hepatocytes (HP:0006561)2.09418009
50Meckel diverticulum (HP:0002245)2.06326401
51Abnormality of the ileum (HP:0001549)2.04859979
52Decreased central vision (HP:0007663)2.04158493
53Abnormality of the renal cortex (HP:0011035)2.03428606
54Optic disc pallor (HP:0000543)2.03113981
55Renal Fanconi syndrome (HP:0001994)2.02304076
56Abnormality of chromosome stability (HP:0003220)2.00875527
57Chromosomal breakage induced by crosslinking agents (HP:0003221)2.00296483
58Anencephaly (HP:0002323)2.00180209
59Increased serum lactate (HP:0002151)1.98223056
60CNS hypomyelination (HP:0003429)1.98020492
61Anophthalmia (HP:0000528)1.94501029
62Agitation (HP:0000713)1.92781919
63Postaxial foot polydactyly (HP:0001830)1.91613687
64Gait imbalance (HP:0002141)1.91136077
65Polyphagia (HP:0002591)1.90670880
66Lactic acidosis (HP:0003128)1.89943745
67Irregular epiphyses (HP:0010582)1.89837868
68Type II lissencephaly (HP:0007260)1.88390095
69Male pseudohermaphroditism (HP:0000037)1.82914326
70Drooling (HP:0002307)1.80161884
71Depressed nasal ridge (HP:0000457)1.79677819
72Methylmalonic acidemia (HP:0002912)1.79609155
73Disproportionate short-trunk short stature (HP:0003521)1.79473048
74Poor suck (HP:0002033)1.78891530
75Lethargy (HP:0001254)1.77520340
76Optic nerve hypoplasia (HP:0000609)1.77204251
77Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.76859488
78Hip dysplasia (HP:0001385)1.75574607
79Asplenia (HP:0001746)1.75249207
80Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.75016984
81CNS demyelination (HP:0007305)1.73686298
82Tubular atrophy (HP:0000092)1.73548927
83Methylmalonic aciduria (HP:0012120)1.73515390
84Abnormality of the proximal phalanges of the hand (HP:0009834)1.73302265
85Aplasia/Hypoplasia of the spleen (HP:0010451)1.73057570
86High anterior hairline (HP:0009890)1.71868083
87Nephrogenic diabetes insipidus (HP:0009806)1.68557345
88Carpal bone hypoplasia (HP:0001498)1.68227241
89Renal cortical cysts (HP:0000803)1.67099926
90Congenital primary aphakia (HP:0007707)1.67080232
91Holoprosencephaly (HP:0001360)1.66023313
92Aplasia/Hypoplasia of the tongue (HP:0010295)1.65746502
93Congenital stationary night blindness (HP:0007642)1.65449644
94Narrow forehead (HP:0000341)1.65329060
95Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.64112588
96Focal motor seizures (HP:0011153)1.64079650
97Bony spicule pigmentary retinopathy (HP:0007737)1.63482888
98Abnormal drinking behavior (HP:0030082)1.63257791
99Polydipsia (HP:0001959)1.63257791
100Cystic liver disease (HP:0006706)1.62905083

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WNK44.14932740
2NME23.67003209
3ZAK3.24023295
4VRK22.64255404
5STK392.64238026
6CASK2.58610552
7CDC72.42213706
8WNK32.39314887
9BMPR1B2.27674766
10STK242.25601057
11PINK12.15267957
12BCKDK2.09981720
13TLK12.05750829
14CCNB12.03759628
15MARK11.93673831
16MKNK21.89877016
17DYRK21.78066724
18PNCK1.69453003
19MAPK131.60041733
20NTRK21.57133415
21STK161.57001798
22EPHB21.53821517
23PDK21.50903771
24ADRBK21.47997871
25WNK11.45505424
26MAP4K21.45465087
27PRKCG1.38172259
28CHEK21.31708481
29MKNK11.29194445
30NME11.25327280
31MAPKAPK51.23890142
32CAMK11.23467945
33GRK11.23402616
34PASK1.20589321
35TNIK1.07879550
36TGFBR11.06601624
37FRK1.05663161
38PHKG21.01331659
39PHKG11.01331659
40VRK10.99976274
41PLK40.99528609
42SRPK10.98428479
43WEE10.97172129
44PRKCQ0.96510386
45MAP3K90.95742381
46DYRK30.93097434
47TXK0.91925283
48MAP3K40.91528533
49MAP3K110.87574954
50PIK3CA0.84910689
51RPS6KA60.84449496
52PLK30.80122563
53CAMK40.78381859
54NUAK10.77406696
55TTK0.77001413
56CDK80.76776998
57PAK30.75149842
58PLK10.74992835
59RPS6KC10.70304689
60RPS6KL10.70304689
61FLT30.69320438
62TIE10.68012725
63MAP2K70.64533713
64INSRR0.63588803
65CSNK1G20.63437486
66AURKA0.63352107
67ADRBK10.62555166
68GRK50.62423569
69CSNK1E0.61353436
70AURKB0.60898985
71CSNK1G30.60367960
72NEK10.59383158
73PRKCZ0.58865329
74ATR0.58518467
75TAF10.58231273
76PRKCE0.55311067
77PRKACA0.54563098
78ABL20.51916148
79CSNK1G10.50916583
80ALK0.49943503
81MUSK0.49657363
82OXSR10.46162914
83CSNK2A20.44602134
84RPS6KA50.43788894
85MINK10.42526705
86DYRK1B0.41573058
87CAMKK10.41072625
88PRKCI0.38637928
89ATM0.36667984
90CSNK2A10.36566914
91BUB10.36362889
92ACVR1B0.35102725
93SGK10.34450196
94CAMK1G0.33351218
95CHEK10.33280488
96CDK90.32624013
97PRKDC0.31933435
98MAP4K10.31846281
99PRKCA0.31222354
100STK110.30034177

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.03334465
2Oxidative phosphorylation_Homo sapiens_hsa001903.42668738
3Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.01326386
4Parkinsons disease_Homo sapiens_hsa050122.93672500
5RNA polymerase_Homo sapiens_hsa030202.67931846
6Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.31452258
7Protein export_Homo sapiens_hsa030602.23184601
8Huntingtons disease_Homo sapiens_hsa050162.18105007
9Homologous recombination_Homo sapiens_hsa034402.16363520
10Cardiac muscle contraction_Homo sapiens_hsa042602.11529353
11Alzheimers disease_Homo sapiens_hsa050102.08783868
12Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.98510248
13Non-homologous end-joining_Homo sapiens_hsa034501.91684456
14DNA replication_Homo sapiens_hsa030301.90979609
15Fanconi anemia pathway_Homo sapiens_hsa034601.90486802
16Pyrimidine metabolism_Homo sapiens_hsa002401.83223677
17Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.82845550
18RNA degradation_Homo sapiens_hsa030181.79970895
19Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.69254815
20Sulfur relay system_Homo sapiens_hsa041221.68461627
21Mismatch repair_Homo sapiens_hsa034301.63421382
22Nicotine addiction_Homo sapiens_hsa050331.61711126
23Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.59168254
24One carbon pool by folate_Homo sapiens_hsa006701.53736395
25Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.51962945
26Proteasome_Homo sapiens_hsa030501.44250213
27Butanoate metabolism_Homo sapiens_hsa006501.43333644
28Propanoate metabolism_Homo sapiens_hsa006401.34006071
29Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.33438611
30Basal transcription factors_Homo sapiens_hsa030221.33417816
31Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.29659294
32Base excision repair_Homo sapiens_hsa034101.29083981
33Phototransduction_Homo sapiens_hsa047441.29071188
34Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.28018498
35Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.27242855
36Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.22680621
37Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.22325326
38Olfactory transduction_Homo sapiens_hsa047401.22042559
39Caffeine metabolism_Homo sapiens_hsa002321.21947491
40Nucleotide excision repair_Homo sapiens_hsa034201.21433495
41Selenocompound metabolism_Homo sapiens_hsa004501.19203742
42Hedgehog signaling pathway_Homo sapiens_hsa043401.17739851
43Purine metabolism_Homo sapiens_hsa002301.10090660
44Spliceosome_Homo sapiens_hsa030401.08389644
45RNA transport_Homo sapiens_hsa030131.03231330
46Basal cell carcinoma_Homo sapiens_hsa052171.00931472
47Linoleic acid metabolism_Homo sapiens_hsa005911.00596964
48Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.87450245
49Pyruvate metabolism_Homo sapiens_hsa006200.82414450
50Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.82279655
51Metabolic pathways_Homo sapiens_hsa011000.81068928
52Tryptophan metabolism_Homo sapiens_hsa003800.80302828
53Taste transduction_Homo sapiens_hsa047420.79510122
54Maturity onset diabetes of the young_Homo sapiens_hsa049500.74541191
55Peroxisome_Homo sapiens_hsa041460.74513558
56alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.70638789
57Fatty acid elongation_Homo sapiens_hsa000620.70177201
58Insulin secretion_Homo sapiens_hsa049110.68502346
59beta-Alanine metabolism_Homo sapiens_hsa004100.65656037
60Cysteine and methionine metabolism_Homo sapiens_hsa002700.65592898
61Tyrosine metabolism_Homo sapiens_hsa003500.65211532
62Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.63993790
63Drug metabolism - other enzymes_Homo sapiens_hsa009830.62851801
64Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.60403698
65Fat digestion and absorption_Homo sapiens_hsa049750.59737069
66Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.57594220
67Arginine and proline metabolism_Homo sapiens_hsa003300.57245515
68Steroid biosynthesis_Homo sapiens_hsa001000.55605348
69N-Glycan biosynthesis_Homo sapiens_hsa005100.51251682
70Dopaminergic synapse_Homo sapiens_hsa047280.50259435
71Nitrogen metabolism_Homo sapiens_hsa009100.49761536
72Chemical carcinogenesis_Homo sapiens_hsa052040.48851409
73Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.48697927
74Retinol metabolism_Homo sapiens_hsa008300.47319688
75Primary bile acid biosynthesis_Homo sapiens_hsa001200.46519636
76Cocaine addiction_Homo sapiens_hsa050300.43543007
77Morphine addiction_Homo sapiens_hsa050320.43521534
78Folate biosynthesis_Homo sapiens_hsa007900.41859401
79Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.41223284
80Arginine biosynthesis_Homo sapiens_hsa002200.40840493
81Ether lipid metabolism_Homo sapiens_hsa005650.40608866
82Circadian entrainment_Homo sapiens_hsa047130.40375555
83Salivary secretion_Homo sapiens_hsa049700.40262255
84Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.39235261
85mRNA surveillance pathway_Homo sapiens_hsa030150.38638559
86Fatty acid degradation_Homo sapiens_hsa000710.38006459
87Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.37757658
88Fatty acid metabolism_Homo sapiens_hsa012120.37317217
89Hippo signaling pathway_Homo sapiens_hsa043900.36468463
90GABAergic synapse_Homo sapiens_hsa047270.35777122
91Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.35093989
92Amphetamine addiction_Homo sapiens_hsa050310.33881300
93Cell cycle_Homo sapiens_hsa041100.32665330
94Arachidonic acid metabolism_Homo sapiens_hsa005900.31909548
95Dorso-ventral axis formation_Homo sapiens_hsa043200.29881298
96Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.27089807
97Steroid hormone biosynthesis_Homo sapiens_hsa001400.25330101
98Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.24319864
99Lysine degradation_Homo sapiens_hsa003100.23048355
100Glutamatergic synapse_Homo sapiens_hsa047240.22853835

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »