Rank | Gene Set | Z-score |
---|---|---|
1 | urate metabolic process (GO:0046415) | 7.23600980 |
2 | drug transmembrane transport (GO:0006855) | 7.01204529 |
3 | tryptophan catabolic process (GO:0006569) | 6.61409807 |
4 | indole-containing compound catabolic process (GO:0042436) | 6.61409807 |
5 | indolalkylamine catabolic process (GO:0046218) | 6.61409807 |
6 | aminoglycoside antibiotic metabolic process (GO:0030647) | 6.42619025 |
7 | aromatic amino acid family catabolic process (GO:0009074) | 6.31384353 |
8 | tryptophan metabolic process (GO:0006568) | 6.21727154 |
9 | lysine metabolic process (GO:0006553) | 6.21215898 |
10 | lysine catabolic process (GO:0006554) | 6.21215898 |
11 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 5.90525196 |
12 | L-phenylalanine catabolic process (GO:0006559) | 5.90525196 |
13 | glyoxylate metabolic process (GO:0046487) | 5.87922656 |
14 | drug transport (GO:0015893) | 5.85691666 |
15 | behavioral response to nicotine (GO:0035095) | 5.70398035 |
16 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 5.70087825 |
17 | L-phenylalanine metabolic process (GO:0006558) | 5.70087825 |
18 | kynurenine metabolic process (GO:0070189) | 5.36070033 |
19 | organic cation transport (GO:0015695) | 5.18164254 |
20 | drug catabolic process (GO:0042737) | 5.15609717 |
21 | exogenous drug catabolic process (GO:0042738) | 5.05483800 |
22 | cysteine metabolic process (GO:0006534) | 5.04957570 |
23 | amine catabolic process (GO:0009310) | 4.78677304 |
24 | cellular biogenic amine catabolic process (GO:0042402) | 4.78677304 |
25 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 4.77732641 |
26 | indolalkylamine metabolic process (GO:0006586) | 4.75464310 |
27 | phosphate ion transport (GO:0006817) | 4.70620097 |
28 | aromatic amino acid family metabolic process (GO:0009072) | 4.56840430 |
29 | serine family amino acid catabolic process (GO:0009071) | 4.56118336 |
30 | amino-acid betaine metabolic process (GO:0006577) | 4.49973310 |
31 | short-chain fatty acid metabolic process (GO:0046459) | 4.36073474 |
32 | bile acid biosynthetic process (GO:0006699) | 4.35849932 |
33 | response to mercury ion (GO:0046689) | 4.34644079 |
34 | * homocysteine metabolic process (GO:0050667) | 4.30500008 |
35 | vitamin D metabolic process (GO:0042359) | 4.18908185 |
36 | phosphate ion transmembrane transport (GO:0035435) | 4.12182372 |
37 | alpha-amino acid catabolic process (GO:1901606) | 4.11801996 |
38 | cellular modified amino acid catabolic process (GO:0042219) | 4.05683599 |
39 | phosphate ion homeostasis (GO:0055062) | 4.04943341 |
40 | trivalent inorganic anion homeostasis (GO:0072506) | 4.04943341 |
41 | quaternary ammonium group transport (GO:0015697) | 3.99908640 |
42 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.96015389 |
43 | indole-containing compound metabolic process (GO:0042430) | 3.92928254 |
44 | aspartate family amino acid catabolic process (GO:0009068) | 3.90064899 |
45 | valine metabolic process (GO:0006573) | 3.88562408 |
46 | branched-chain amino acid metabolic process (GO:0009081) | 3.87989037 |
47 | excretion (GO:0007588) | 3.87061166 |
48 | cellular amino acid catabolic process (GO:0009063) | 3.84838974 |
49 | serine family amino acid metabolic process (GO:0009069) | 3.77857907 |
50 | benzene-containing compound metabolic process (GO:0042537) | 3.77683880 |
51 | fructose metabolic process (GO:0006000) | 3.75701001 |
52 | NAD biosynthetic process (GO:0009435) | 3.75569849 |
53 | sulfur amino acid catabolic process (GO:0000098) | 3.72303804 |
54 | cellular glucuronidation (GO:0052695) | 3.70906867 |
55 | urea metabolic process (GO:0019627) | 3.67582907 |
56 | urea cycle (GO:0000050) | 3.67582907 |
57 | uronic acid metabolic process (GO:0006063) | 3.66115438 |
58 | glucuronate metabolic process (GO:0019585) | 3.66115438 |
59 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.66109101 |
60 | carnitine metabolic process (GO:0009437) | 3.65719229 |
61 | platelet dense granule organization (GO:0060155) | 3.65282660 |
62 | fatty acid beta-oxidation (GO:0006635) | 3.64945898 |
63 | cellular ketone body metabolic process (GO:0046950) | 3.63294879 |
64 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.62114633 |
65 | NADH dehydrogenase complex assembly (GO:0010257) | 3.62114633 |
66 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.62114633 |
67 | branched-chain amino acid catabolic process (GO:0009083) | 3.60784647 |
68 | aldehyde catabolic process (GO:0046185) | 3.54509592 |
69 | glutamate metabolic process (GO:0006536) | 3.53313576 |
70 | acetyl-CoA metabolic process (GO:0006084) | 3.52597110 |
71 | coenzyme catabolic process (GO:0009109) | 3.50363631 |
72 | 2-oxoglutarate metabolic process (GO:0006103) | 3.50016855 |
73 | bile acid metabolic process (GO:0008206) | 3.49288418 |
74 | fatty acid oxidation (GO:0019395) | 3.48621468 |
75 | tyrosine metabolic process (GO:0006570) | 3.46964603 |
76 | nicotinamide nucleotide biosynthetic process (GO:0019359) | 3.45470090 |
77 | pyridine nucleotide biosynthetic process (GO:0019363) | 3.45470090 |
78 | renal absorption (GO:0070293) | 3.45199076 |
79 | lipid oxidation (GO:0034440) | 3.45063340 |
80 | organic acid catabolic process (GO:0016054) | 3.44383661 |
81 | carboxylic acid catabolic process (GO:0046395) | 3.44383661 |
82 | protein-cofactor linkage (GO:0018065) | 3.42974113 |
83 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.42170030 |
84 | detection of light stimulus involved in visual perception (GO:0050908) | 3.39163469 |
85 | detection of light stimulus involved in sensory perception (GO:0050962) | 3.39163469 |
86 | nitrogen cycle metabolic process (GO:0071941) | 3.38739559 |
87 | complement activation, alternative pathway (GO:0006957) | 3.38316940 |
88 | lymphangiogenesis (GO:0001946) | 3.32465239 |
89 | nonmotile primary cilium assembly (GO:0035058) | 3.30581632 |
90 | cullin deneddylation (GO:0010388) | 3.29585935 |
91 | regulation of protein activation cascade (GO:2000257) | 3.28812139 |
92 | regulation of bile acid biosynthetic process (GO:0070857) | 3.27932139 |
93 | dicarboxylic acid biosynthetic process (GO:0043650) | 3.26879188 |
94 | toxin transport (GO:1901998) | 3.22976475 |
95 | sulfation (GO:0051923) | 3.22190506 |
96 | metanephric nephron tubule development (GO:0072234) | 3.21128185 |
97 | metanephric tubule development (GO:0072170) | 3.21128185 |
98 | regulation of complement activation (GO:0030449) | 3.20765647 |
99 | fatty acid catabolic process (GO:0009062) | 3.20049381 |
100 | cellular response to ATP (GO:0071318) | 3.19963459 |
101 | monocarboxylic acid catabolic process (GO:0072329) | 3.19065077 |
102 | tricarboxylic acid metabolic process (GO:0072350) | 3.15736044 |
103 | protein complex biogenesis (GO:0070271) | 3.15666785 |
104 | proline metabolic process (GO:0006560) | 3.14989283 |
105 | gamma-aminobutyric acid transport (GO:0015812) | 3.12445407 |
106 | ethanol oxidation (GO:0006069) | 3.11725326 |
107 | ketone body metabolic process (GO:1902224) | 3.10113902 |
108 | response to phenylpropanoid (GO:0080184) | 3.09339897 |
109 | protein deneddylation (GO:0000338) | 3.08903520 |
110 | nonribosomal peptide biosynthetic process (GO:0019184) | 3.08060309 |
111 | cilium morphogenesis (GO:0060271) | 3.07867280 |
112 | polyol transport (GO:0015791) | 3.07216454 |
113 | carnitine transport (GO:0015879) | 3.06676241 |
114 | amino-acid betaine transport (GO:0015838) | 3.06676241 |
115 | somite development (GO:0061053) | 3.05040902 |
116 | serine family amino acid biosynthetic process (GO:0009070) | 3.04045713 |
117 | drug metabolic process (GO:0017144) | 3.00998820 |
118 | cell proliferation in forebrain (GO:0021846) | 3.00032116 |
119 | small molecule catabolic process (GO:0044282) | 2.99387623 |
120 | arginine metabolic process (GO:0006525) | 2.98480506 |
121 | peptidyl-glutamic acid carboxylation (GO:0017187) | 2.97901876 |
122 | protein carboxylation (GO:0018214) | 2.97901876 |
123 | photoreceptor cell maintenance (GO:0045494) | 2.97752123 |
124 | fucose catabolic process (GO:0019317) | 2.96120152 |
125 | L-fucose metabolic process (GO:0042354) | 2.96120152 |
126 | L-fucose catabolic process (GO:0042355) | 2.96120152 |
127 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.90342707 |
128 | inner ear receptor stereocilium organization (GO:0060122) | 2.87834731 |
129 | epithelial cilium movement (GO:0003351) | 2.87706352 |
130 | cornea development in camera-type eye (GO:0061303) | 2.83049682 |
131 | protein polyglutamylation (GO:0018095) | 2.82631273 |
132 | photoreceptor cell development (GO:0042461) | 2.81733215 |
133 | protein neddylation (GO:0045116) | 2.80057220 |
134 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.77038441 |
135 | reflex (GO:0060004) | 2.72872260 |
136 | DNA deamination (GO:0045006) | 2.69781159 |
137 | retinal ganglion cell axon guidance (GO:0031290) | 2.66643662 |
138 | response to pheromone (GO:0019236) | 2.63612915 |
139 | negative regulation of appetite (GO:0032099) | 2.62392294 |
140 | negative regulation of response to food (GO:0032096) | 2.62392294 |
141 | limb development (GO:0060173) | 2.60681295 |
142 | appendage development (GO:0048736) | 2.60681295 |
143 | protein K6-linked ubiquitination (GO:0085020) | 2.60294870 |
144 | negative regulation of systemic arterial blood pressure (GO:0003085) | 2.59886496 |
145 | intraciliary transport (GO:0042073) | 2.58900972 |
146 | auditory receptor cell stereocilium organization (GO:0060088) | 2.57906546 |
147 | pseudouridine synthesis (GO:0001522) | 2.57751903 |
148 | negative regulation of mast cell activation (GO:0033004) | 2.54468797 |
149 | regulation of hippo signaling (GO:0035330) | 2.53773901 |
150 | cilium or flagellum-dependent cell motility (GO:0001539) | 2.53549097 |
151 | visual perception (GO:0007601) | 2.52574299 |
152 | artery development (GO:0060840) | 2.51679506 |
153 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.51592711 |
154 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.50850984 |
155 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.50850984 |
156 | sensory perception of light stimulus (GO:0050953) | 2.50467275 |
157 | transmission of nerve impulse (GO:0019226) | 2.48172245 |
158 | primary amino compound metabolic process (GO:1901160) | 2.47617278 |
159 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.47368538 |
160 | behavioral response to ethanol (GO:0048149) | 2.46841818 |
161 | cilium organization (GO:0044782) | 2.46652497 |
162 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.46390273 |
163 | negative chemotaxis (GO:0050919) | 2.45705588 |
164 | retinal cone cell development (GO:0046549) | 2.45649196 |
165 | eye photoreceptor cell development (GO:0042462) | 2.43789153 |
166 | cAMP catabolic process (GO:0006198) | 2.43512180 |
167 | negative regulation of telomere maintenance (GO:0032205) | 2.43154679 |
168 | kidney morphogenesis (GO:0060993) | 2.41812481 |
169 | cilium assembly (GO:0042384) | 2.40355487 |
170 | detection of mechanical stimulus involved in sensory perception (GO:0050974) | 2.39984038 |
171 | mannosylation (GO:0097502) | 2.38606615 |
172 | neuronal action potential (GO:0019228) | 2.38270873 |
173 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.38138866 |
174 | positive regulation of oligodendrocyte differentiation (GO:0048714) | 2.38091666 |
175 | regulation of cilium movement (GO:0003352) | 2.35826621 |
176 | smoothened signaling pathway (GO:0007224) | 2.35819721 |
177 | positive regulation of fatty acid oxidation (GO:0046321) | 2.35655440 |
178 | nephron epithelium morphogenesis (GO:0072088) | 2.35179999 |
179 | nephron tubule morphogenesis (GO:0072078) | 2.35179999 |
180 | limb bud formation (GO:0060174) | 2.34913465 |
181 | regulation of rhodopsin mediated signaling pathway (GO:0022400) | 2.34550098 |
182 | retina development in camera-type eye (GO:0060041) | 2.33570261 |
183 | multicellular organism reproduction (GO:0032504) | 2.32749096 |
184 | startle response (GO:0001964) | 2.32368123 |
185 | regulation of glomerulus development (GO:0090192) | 2.30934412 |
186 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.30377609 |
187 | outer ear morphogenesis (GO:0042473) | 2.30245196 |
188 | regulation of mesoderm development (GO:2000380) | 2.30133782 |
189 | cardiovascular system development (GO:0072358) | 2.29965944 |
190 | rhodopsin mediated signaling pathway (GO:0016056) | 2.29780767 |
191 | respiratory chain complex IV assembly (GO:0008535) | 2.28965436 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 5.47511957 |
2 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 4.29137625 |
3 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 4.20609921 |
4 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 3.39182849 |
5 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 3.38122977 |
6 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.34685422 |
7 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.20531309 |
8 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.81614084 |
9 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.62719667 |
10 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 2.49938435 |
11 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 2.46245195 |
12 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.39220160 |
13 | EWS_26573619_Chip-Seq_HEK293_Human | 2.30973454 |
14 | FUS_26573619_Chip-Seq_HEK293_Human | 2.24094628 |
15 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 2.01498836 |
16 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.92174802 |
17 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.90822716 |
18 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.90454194 |
19 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.88730703 |
20 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.86594421 |
21 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.85667165 |
22 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.85518429 |
23 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.83566879 |
24 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.82856042 |
25 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.80615445 |
26 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.80018521 |
27 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.79468900 |
28 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.78159389 |
29 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.73155302 |
30 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.71437156 |
31 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.70731594 |
32 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.69290400 |
33 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.61489573 |
34 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.60647739 |
35 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.59425040 |
36 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.58038852 |
37 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.52883839 |
38 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.52290720 |
39 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.50244536 |
40 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.47988394 |
41 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.47649966 |
42 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.46655040 |
43 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.46625311 |
44 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.46625311 |
45 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.46377427 |
46 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.46055084 |
47 | STAT3_23295773_ChIP-Seq_U87_Human | 1.45835947 |
48 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.45175834 |
49 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.43089756 |
50 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.41120438 |
51 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.39245602 |
52 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.37901092 |
53 | TCF4_23295773_ChIP-Seq_U87_Human | 1.37747569 |
54 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.37530512 |
55 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.37403219 |
56 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.35729995 |
57 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.35335921 |
58 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.35058443 |
59 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.34778239 |
60 | P300_19829295_ChIP-Seq_ESCs_Human | 1.34559850 |
61 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.34252842 |
62 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.33606793 |
63 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.33165586 |
64 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.32729319 |
65 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.32550758 |
66 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.32529941 |
67 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.32115037 |
68 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.32046869 |
69 | * SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.31789708 |
70 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.31574195 |
71 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.30829846 |
72 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.30362845 |
73 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.30212205 |
74 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.30030879 |
75 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.29817787 |
76 | TP53_16413492_ChIP-PET_HCT116_Human | 1.29773718 |
77 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 1.29306273 |
78 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.28856062 |
79 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.28415522 |
80 | AR_25329375_ChIP-Seq_VCAP_Human | 1.27202893 |
81 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.27202614 |
82 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.27134920 |
83 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.27021984 |
84 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.26669765 |
85 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.25690892 |
86 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.25115130 |
87 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.24725729 |
88 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.24157257 |
89 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.23677632 |
90 | ESRRB_18555785_Chip-Seq_ESCs_Mouse | 1.23380133 |
91 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.23161453 |
92 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.22717719 |
93 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.21740619 |
94 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.21362032 |
95 | ZFX_18555785_Chip-Seq_ESCs_Mouse | 1.20136976 |
96 | PU1_27457419_Chip-Seq_LIVER_Mouse | 1.19504802 |
97 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.19467552 |
98 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.19467552 |
99 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.19265079 |
100 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.19265079 |
101 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.19202819 |
102 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.19189096 |
103 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.19127573 |
104 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.18688213 |
105 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 1.17202784 |
106 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.16636416 |
107 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 1.16608829 |
108 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.16605031 |
109 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 1.16337370 |
110 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.15854444 |
111 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.15481330 |
112 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.14389884 |
113 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.13778150 |
114 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.13495896 |
115 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.13391977 |
116 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 1.12972124 |
117 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.12734204 |
118 | JUN_21703547_ChIP-Seq_K562_Human | 1.12523467 |
119 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.12422739 |
120 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.12387223 |
121 | VDR_22108803_ChIP-Seq_LS180_Human | 1.11688778 |
122 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.11150042 |
123 | STAT1_17558387_ChIP-Seq_HELA_Human | 1.11084255 |
124 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.09959697 |
125 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.07464246 |
126 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.07354898 |
127 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.07354898 |
128 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.06412225 |
129 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.06255088 |
130 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.06255088 |
131 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.06240426 |
132 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.06158707 |
133 | * KAP1_22055183_ChIP-Seq_ESCs_Mouse | 1.04618771 |
134 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 1.04510164 |
135 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.03846067 |
136 | KDM2B_26808549_Chip-Seq_REH_Human | 1.03386153 |
137 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.03169689 |
138 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.03135479 |
139 | CJUN_26792858_Chip-Seq_BT549_Human | 1.02678634 |
140 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.02675102 |
141 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.01593259 |
142 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.01414300 |
143 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.00749475 |
144 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.00524771 |
145 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.99827266 |
146 | HNF4A_19822575_ChIP-Seq_HepG2_Human | 0.98803292 |
147 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 0.98685437 |
148 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.97537471 |
149 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.97151735 |
150 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.97148118 |
151 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 0.96870926 |
152 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.96656974 |
153 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 0.96612067 |
154 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 0.93562121 |
155 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.93220233 |
156 | * FOXM1_26456572_ChIP-Seq_MCF-7_Human | 0.92809883 |
157 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.92721862 |
158 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.90474879 |
159 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.88987035 |
160 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.88405736 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005360_urolithiasis | 7.94824632 |
2 | MP0002139_abnormal_hepatobiliary_system | 6.32503645 |
3 | MP0005085_abnormal_gallbladder_physiolo | 4.60840076 |
4 | MP0004019_abnormal_vitamin_homeostasis | 4.38753732 |
5 | MP0005365_abnormal_bile_salt | 4.37350962 |
6 | MP0003195_calcinosis | 4.31828603 |
7 | MP0003252_abnormal_bile_duct | 4.05086855 |
8 | MP0002138_abnormal_hepatobiliary_system | 4.04568366 |
9 | MP0005332_abnormal_amino_acid | 3.89881789 |
10 | MP0008875_abnormal_xenobiotic_pharmacok | 3.61090396 |
11 | MP0004043_abnormal_pH_regulation | 3.36455653 |
12 | MP0002102_abnormal_ear_morphology | 3.29313524 |
13 | MP0009643_abnormal_urine_homeostasis | 2.66063040 |
14 | MP0005551_abnormal_eye_electrophysiolog | 2.57616872 |
15 | MP0003646_muscle_fatigue | 2.20039220 |
16 | MP0006072_abnormal_retinal_apoptosis | 2.19848775 |
17 | MP0001765_abnormal_ion_homeostasis | 2.18394827 |
18 | MP0001958_emphysema | 2.18134408 |
19 | MP0003136_yellow_coat_color | 2.13074990 |
20 | MP0005253_abnormal_eye_physiology | 2.11637328 |
21 | MP0005636_abnormal_mineral_homeostasis | 2.11631489 |
22 | MP0002876_abnormal_thyroid_physiology | 2.04828005 |
23 | MP0004133_heterotaxia | 2.02428073 |
24 | MP0005451_abnormal_body_composition | 1.96990399 |
25 | MP0001756_abnormal_urination | 1.94048685 |
26 | MP0006292_abnormal_olfactory_placode | 1.89179207 |
27 | * MP0002136_abnormal_kidney_physiology | 1.88972802 |
28 | MP0000049_abnormal_middle_ear | 1.85886319 |
29 | MP0002837_dystrophic_cardiac_calcinosis | 1.82596010 |
30 | MP0010329_abnormal_lipoprotein_level | 1.81328606 |
31 | MP0004145_abnormal_muscle_electrophysio | 1.81179822 |
32 | MP0003283_abnormal_digestive_organ | 1.80685846 |
33 | MP0008877_abnormal_DNA_methylation | 1.80538493 |
34 | MP0004142_abnormal_muscle_tone | 1.76719410 |
35 | MP0003806_abnormal_nucleotide_metabolis | 1.76687208 |
36 | MP0002638_abnormal_pupillary_reflex | 1.75633161 |
37 | MP0001485_abnormal_pinna_reflex | 1.74215808 |
38 | MP0009046_muscle_twitch | 1.72352402 |
39 | MP0002938_white_spotting | 1.65885276 |
40 | MP0001968_abnormal_touch/_nociception | 1.64174744 |
41 | MP0005670_abnormal_white_adipose | 1.62947703 |
42 | MP0009250_abnormal_appendicular_skeleto | 1.62528528 |
43 | MP0002736_abnormal_nociception_after | 1.57325544 |
44 | MP0002653_abnormal_ependyma_morphology | 1.54580360 |
45 | MP0001764_abnormal_homeostasis | 1.54086451 |
46 | MP0001666_abnormal_nutrient_absorption | 1.53752566 |
47 | MP0006276_abnormal_autonomic_nervous | 1.52146883 |
48 | MP0002928_abnormal_bile_duct | 1.51113966 |
49 | MP0000538_abnormal_urinary_bladder | 1.49918861 |
50 | MP0000631_abnormal_neuroendocrine_gland | 1.49400060 |
51 | MP0010030_abnormal_orbit_morphology | 1.46908369 |
52 | MP0000372_irregular_coat_pigmentation | 1.46130721 |
53 | MP0005084_abnormal_gallbladder_morpholo | 1.45045060 |
54 | MP0005319_abnormal_enzyme/_coenzyme | 1.43198610 |
55 | MP0009697_abnormal_copulation | 1.42401214 |
56 | MP0004215_abnormal_myocardial_fiber | 1.37753705 |
57 | MP0001986_abnormal_taste_sensitivity | 1.35483476 |
58 | MP0002272_abnormal_nervous_system | 1.35275367 |
59 | MP0005584_abnormal_enzyme/coenzyme_acti | 1.34052119 |
60 | MP0005195_abnormal_posterior_eye | 1.34038504 |
61 | MP0008872_abnormal_physiological_respon | 1.32558628 |
62 | MP0003191_abnormal_cellular_cholesterol | 1.32392479 |
63 | MP0003868_abnormal_feces_composition | 1.30649348 |
64 | MP0003937_abnormal_limbs/digits/tail_de | 1.30285521 |
65 | MP0009745_abnormal_behavioral_response | 1.29201205 |
66 | MP0005167_abnormal_blood-brain_barrier | 1.28439312 |
67 | MP0005083_abnormal_biliary_tract | 1.28116191 |
68 | MP0002168_other_aberrant_phenotype | 1.28076176 |
69 | MP0005503_abnormal_tendon_morphology | 1.27614715 |
70 | MP0002163_abnormal_gland_morphology | 1.25697065 |
71 | MP0004134_abnormal_chest_morphology | 1.25418621 |
72 | MP0005377_hearing/vestibular/ear_phenot | 1.25388240 |
73 | MP0003878_abnormal_ear_physiology | 1.25388240 |
74 | MP0004782_abnormal_surfactant_physiolog | 1.25037468 |
75 | MP0003724_increased_susceptibility_to | 1.24988567 |
76 | MP0002118_abnormal_lipid_homeostasis | 1.23900699 |
77 | MP0003880_abnormal_central_pattern | 1.23566937 |
78 | MP0008775_abnormal_heart_ventricle | 1.23113396 |
79 | MP0001486_abnormal_startle_reflex | 1.21828104 |
80 | * MP0009764_decreased_sensitivity_to | 1.21526730 |
81 | MP0000778_abnormal_nervous_system | 1.19789483 |
82 | MP0001529_abnormal_vocalization | 1.19233003 |
83 | MP0003787_abnormal_imprinting | 1.18910705 |
84 | * MP0003186_abnormal_redox_activity | 1.14107896 |
85 | MP0002282_abnormal_trachea_morphology | 1.13841087 |
86 | MP0000427_abnormal_hair_cycle | 1.13261553 |
87 | MP0004742_abnormal_vestibular_system | 1.09842597 |
88 | MP0002752_abnormal_somatic_nervous | 1.09451186 |
89 | MP0001293_anophthalmia | 1.08959302 |
90 | MP0006054_spinal_hemorrhage | 1.07691893 |
91 | MP0005389_reproductive_system_phenotype | 1.03795040 |
92 | MP0002160_abnormal_reproductive_system | 1.03213450 |
93 | MP0000609_abnormal_liver_physiology | 1.02931422 |
94 | MP0005187_abnormal_penis_morphology | 1.00813483 |
95 | MP0000230_abnormal_systemic_arterial | 1.00513613 |
96 | MP0008789_abnormal_olfactory_epithelium | 0.99110503 |
97 | MP0005391_vision/eye_phenotype | 0.98988287 |
98 | MP0002751_abnormal_autonomic_nervous | 0.98781572 |
99 | MP0005647_abnormal_sex_gland | 0.98749544 |
100 | MP0002557_abnormal_social/conspecific_i | 0.96972453 |
101 | MP0003119_abnormal_digestive_system | 0.96821845 |
102 | MP0003755_abnormal_palate_morphology | 0.96751289 |
103 | MP0003011_delayed_dark_adaptation | 0.96353549 |
104 | MP0003122_maternal_imprinting | 0.95189962 |
105 | MP0008438_abnormal_cutaneous_collagen | 0.93942178 |
106 | MP0010368_abnormal_lymphatic_system | 0.93776258 |
107 | MP0001502_abnormal_circadian_rhythm | 0.91597671 |
108 | MP0002233_abnormal_nose_morphology | 0.90748709 |
109 | MP0001324_abnormal_eye_pigmentation | 0.89429655 |
110 | MP0000647_abnormal_sebaceous_gland | 0.89267698 |
111 | MP0009384_cardiac_valve_regurgitation | 0.88833640 |
112 | MP0004272_abnormal_basement_membrane | 0.88280461 |
113 | MP0002734_abnormal_mechanical_nocicepti | 0.87577866 |
114 | MP0001963_abnormal_hearing_physiology | 0.87335711 |
115 | MP0005220_abnormal_exocrine_pancreas | 0.86425408 |
116 | MP0002572_abnormal_emotion/affect_behav | 0.85445339 |
117 | MP0005379_endocrine/exocrine_gland_phen | 0.84968297 |
118 | MP0001970_abnormal_pain_threshold | 0.84319393 |
119 | MP0005535_abnormal_body_temperature | 0.83946180 |
120 | MP0001984_abnormal_olfaction | 0.83740655 |
121 | MP0004085_abnormal_heartbeat | 0.83735275 |
122 | MP0010386_abnormal_urinary_bladder | 0.82670491 |
123 | MP0003121_genomic_imprinting | 0.82264255 |
124 | MP0002733_abnormal_thermal_nociception | 0.81593613 |
125 | MP0001501_abnormal_sleep_pattern | 0.81026635 |
126 | MP0002067_abnormal_sensory_capabilities | 0.80340714 |
127 | MP0005508_abnormal_skeleton_morphology | 0.79501500 |
128 | MP0002064_seizures | 0.79439763 |
129 | MP0002135_abnormal_kidney_morphology | 0.77822688 |
130 | MP0008469_abnormal_protein_level | 0.77788229 |
131 | MP0004924_abnormal_behavior | 0.77419388 |
132 | MP0005386_behavior/neurological_phenoty | 0.77419388 |
133 | MP0009642_abnormal_blood_homeostasis | 0.77411742 |
134 | MP0002184_abnormal_innervation | 0.77272226 |
135 | MP0005395_other_phenotype | 0.77198702 |
136 | MP0002735_abnormal_chemical_nociception | 0.76630636 |
137 | MP0001286_abnormal_eye_development | 0.76238917 |
138 | MP0004147_increased_porphyrin_level | 0.73317745 |
139 | MP0001177_atelectasis | 0.69996375 |
140 | MP0005408_hypopigmentation | 0.67359036 |
141 | MP0005058_abnormal_lysosome_morphology | 0.66129085 |
142 | MP0005646_abnormal_pituitary_gland | 0.64875679 |
143 | MP0001661_extended_life_span | 0.64751486 |
144 | MP0002896_abnormal_bone_mineralization | 0.63151848 |
145 | MP0000566_synostosis | 0.61952603 |
146 | MP0002108_abnormal_muscle_morphology | 0.60461416 |
147 | MP0005257_abnormal_intraocular_pressure | 0.58816836 |
148 | MP0005595_abnormal_vascular_smooth | 0.56612852 |
149 | MP0000678_abnormal_parathyroid_gland | 0.55507892 |
150 | MP0000598_abnormal_liver_morphology | 0.55477961 |
151 | MP0000579_abnormal_nail_morphology | 0.55128762 |
152 | MP0002998_abnormal_bone_remodeling | 0.52374416 |
153 | MP0002115_abnormal_skeleton_extremities | 0.50452113 |
154 | MP0003941_abnormal_skin_development | 0.50014162 |
155 | MP0002295_abnormal_pulmonary_circulatio | 0.49989111 |
156 | MP0009763_increased_sensitivity_to | 0.49566261 |
157 | MP0000163_abnormal_cartilage_morphology | 0.48900498 |
158 | MP0005275_abnormal_skin_tensile | 0.48642573 |
159 | MP0003638_abnormal_response/metabolism_ | 0.47484822 |
160 | MP0001542_abnormal_bone_strength | 0.47296732 |
161 | MP0000383_abnormal_hair_follicle | 0.46299680 |
162 | MP0001879_abnormal_lymphatic_vessel | 0.45732938 |
163 | MP0002098_abnormal_vibrissa_morphology | 0.45138983 |
164 | MP0006082_CNS_inflammation | 0.43964297 |
165 | MP0001188_hyperpigmentation | 0.43472744 |
166 | MP0004885_abnormal_endolymph | 0.42958252 |
167 | MP0002060_abnormal_skin_morphology | 0.42699371 |
168 | MP0008961_abnormal_basal_metabolism | 0.41991122 |
169 | MP0005376_homeostasis/metabolism_phenot | 0.39933635 |
170 | MP0002078_abnormal_glucose_homeostasis | 0.39440334 |
171 | MP0003300_gastrointestinal_ulcer | 0.39207459 |
172 | MP0005171_absent_coat_pigmentation | 0.38743408 |
173 | MP0002254_reproductive_system_inflammat | 0.38674087 |
174 | MP0003959_abnormal_lean_body | 0.38585048 |
175 | MP0000026_abnormal_inner_ear | 0.38575330 |
176 | MP0002132_abnormal_respiratory_system | 0.38461475 |
177 | MP0005334_abnormal_fat_pad | 0.37880585 |
178 | MP0003953_abnormal_hormone_level | 0.37876822 |
179 | MP0005666_abnormal_adipose_tissue | 0.37473458 |
180 | MP0009765_abnormal_xenobiotic_induced | 0.36319547 |
181 | MP0005248_abnormal_Harderian_gland | 0.35816822 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Increased circulating renin level (HP:0000848) | 5.90986680 |
2 | Hyperactive renin-angiotensin system (HP:0000841) | 5.70199169 |
3 | Metabolic alkalosis (HP:0200114) | 5.48919996 |
4 | Hypokalemic alkalosis (HP:0001949) | 5.45680504 |
5 | Hypomagnesemia (HP:0002917) | 5.36735443 |
6 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 5.28360618 |
7 | Gout (HP:0001997) | 5.15720638 |
8 | Polyuria (HP:0000103) | 4.99527794 |
9 | Abnormality of chloride homeostasis (HP:0011422) | 4.85987568 |
10 | Proximal tubulopathy (HP:0000114) | 4.82349979 |
11 | Abnormal urine output (HP:0012590) | 4.76042459 |
12 | Hyperglycinuria (HP:0003108) | 4.60439263 |
13 | Abnormality of renal excretion (HP:0011036) | 4.55787921 |
14 | Pancreatic cysts (HP:0001737) | 4.54282448 |
15 | Pancreatic fibrosis (HP:0100732) | 4.52608916 |
16 | Tetany (HP:0001281) | 4.41424080 |
17 | Alkalosis (HP:0001948) | 4.36424009 |
18 | Abnormality of magnesium homeostasis (HP:0004921) | 4.33549509 |
19 | Molar tooth sign on MRI (HP:0002419) | 4.22897074 |
20 | Abnormality of midbrain morphology (HP:0002418) | 4.22897074 |
21 | True hermaphroditism (HP:0010459) | 4.21890880 |
22 | Polydipsia (HP:0001959) | 4.00910492 |
23 | Abnormal drinking behavior (HP:0030082) | 4.00910492 |
24 | Abnormality of purine metabolism (HP:0004352) | 3.99681912 |
25 | Increased purine levels (HP:0004368) | 3.93929957 |
26 | Hyperuricemia (HP:0002149) | 3.93929957 |
27 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 3.90789153 |
28 | Abnormality of renin-angiotensin system (HP:0000847) | 3.90598667 |
29 | Abnormality of serine family amino acid metabolism (HP:0010894) | 3.88948005 |
30 | Abnormality of glycine metabolism (HP:0010895) | 3.88948005 |
31 | Increased corneal curvature (HP:0100692) | 3.87907125 |
32 | Keratoconus (HP:0000563) | 3.87907125 |
33 | Hyperaldosteronism (HP:0000859) | 3.84572925 |
34 | Congenital stationary night blindness (HP:0007642) | 3.81571089 |
35 | Intrahepatic cholestasis (HP:0001406) | 3.77395737 |
36 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 3.77002429 |
37 | Pendular nystagmus (HP:0012043) | 3.76789334 |
38 | Generalized aminoaciduria (HP:0002909) | 3.67108607 |
39 | Abnormality of nucleobase metabolism (HP:0010932) | 3.57532120 |
40 | Hydroxyprolinuria (HP:0003080) | 3.45765000 |
41 | Abnormality of proline metabolism (HP:0010907) | 3.45765000 |
42 | Nephronophthisis (HP:0000090) | 3.42710071 |
43 | Hyperglycinemia (HP:0002154) | 3.36045394 |
44 | Renal salt wasting (HP:0000127) | 3.34816357 |
45 | Vascular calcification (HP:0004934) | 3.34602234 |
46 | Renal tubular acidosis (HP:0001947) | 3.27679608 |
47 | Abolished electroretinogram (ERG) (HP:0000550) | 3.27330084 |
48 | Ketosis (HP:0001946) | 3.27169641 |
49 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 3.20321897 |
50 | Cardiovascular calcification (HP:0011915) | 3.18468378 |
51 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 3.14967008 |
52 | Ketoacidosis (HP:0001993) | 3.13998979 |
53 | Abnormality of the renal medulla (HP:0100957) | 3.06174140 |
54 | Enlarged kidneys (HP:0000105) | 3.03305332 |
55 | Xanthomatosis (HP:0000991) | 3.02364150 |
56 | Abnormality of fatty-acid metabolism (HP:0004359) | 3.00952346 |
57 | Chronic hepatic failure (HP:0100626) | 2.98953261 |
58 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 2.98917689 |
59 | Hyperammonemia (HP:0001987) | 2.97458491 |
60 | Glycosuria (HP:0003076) | 2.96113585 |
61 | Abnormality of urine glucose concentration (HP:0011016) | 2.96113585 |
62 | Short tibia (HP:0005736) | 2.92289831 |
63 | Hypokalemia (HP:0002900) | 2.92118396 |
64 | Chorioretinal atrophy (HP:0000533) | 2.91773296 |
65 | Hypercalciuria (HP:0002150) | 2.90797823 |
66 | Conjugated hyperbilirubinemia (HP:0002908) | 2.87579715 |
67 | Cystic liver disease (HP:0006706) | 2.83894055 |
68 | Joint hemorrhage (HP:0005261) | 2.78201063 |
69 | Medial flaring of the eyebrow (HP:0010747) | 2.77646635 |
70 | Delayed CNS myelination (HP:0002188) | 2.77206691 |
71 | Rickets (HP:0002748) | 2.74008082 |
72 | Abnormality of pyrimidine metabolism (HP:0004353) | 2.73232535 |
73 | Prolonged partial thromboplastin time (HP:0003645) | 2.69368145 |
74 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.66593466 |
75 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.62066506 |
76 | Deep venous thrombosis (HP:0002625) | 2.59201769 |
77 | Type II lissencephaly (HP:0007260) | 2.58884930 |
78 | Widely patent fontanelles and sutures (HP:0004492) | 2.58352931 |
79 | Attenuation of retinal blood vessels (HP:0007843) | 2.57699881 |
80 | Abnormality of potassium homeostasis (HP:0011042) | 2.56810299 |
81 | Acute necrotizing encephalopathy (HP:0006965) | 2.56480042 |
82 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.55173306 |
83 | Tubular atrophy (HP:0000092) | 2.53342136 |
84 | Decreased central vision (HP:0007663) | 2.53286595 |
85 | Nephrocalcinosis (HP:0000121) | 2.50701793 |
86 | Metabolic acidosis (HP:0001942) | 2.50265658 |
87 | Alveolar cell carcinoma (HP:0006519) | 2.49115417 |
88 | Complement deficiency (HP:0004431) | 2.49105527 |
89 | Abnormality of serum amino acid levels (HP:0003112) | 2.47404794 |
90 | Renal cortical cysts (HP:0000803) | 2.47342922 |
91 | Hypophosphatemia (HP:0002148) | 2.43209931 |
92 | Sclerocornea (HP:0000647) | 2.42748797 |
93 | Nephrolithiasis (HP:0000787) | 2.42165086 |
94 | Congenital hepatic fibrosis (HP:0002612) | 2.38113586 |
95 | Congenital sensorineural hearing impairment (HP:0008527) | 2.37557364 |
96 | Hepatocellular carcinoma (HP:0001402) | 2.37438711 |
97 | Dicarboxylic aciduria (HP:0003215) | 2.37348112 |
98 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.37348112 |
99 | Hypophosphatemic rickets (HP:0004912) | 2.36693285 |
100 | Acute encephalopathy (HP:0006846) | 2.36360061 |
101 | Hyperalaninemia (HP:0003348) | 2.35857641 |
102 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.35857641 |
103 | Abnormality of alanine metabolism (HP:0010916) | 2.35857641 |
104 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.35709240 |
105 | Abnormal number of erythroid precursors (HP:0012131) | 2.32357070 |
106 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.32068772 |
107 | Postaxial foot polydactyly (HP:0001830) | 2.28619151 |
108 | Abnormality of the renal cortex (HP:0011035) | 2.26857351 |
109 | Anencephaly (HP:0002323) | 2.25056752 |
110 | Abnormality of methionine metabolism (HP:0010901) | 2.24751138 |
111 | Fat malabsorption (HP:0002630) | 2.23687736 |
112 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.23547741 |
113 | Progressive macrocephaly (HP:0004481) | 2.22903974 |
114 | 3-Methylglutaconic aciduria (HP:0003535) | 2.22211087 |
115 | Vomiting (HP:0002013) | 2.21993771 |
116 | Lethargy (HP:0001254) | 2.21370278 |
117 | Abnormal enzyme/coenzyme activity (HP:0012379) | 2.18682139 |
118 | Abnormal urine phosphate concentration (HP:0012599) | 2.18538772 |
119 | Optic nerve hypoplasia (HP:0000609) | 2.17975041 |
120 | Mitochondrial inheritance (HP:0001427) | 2.16335060 |
121 | Hypoglycemic coma (HP:0001325) | 2.15536964 |
122 | Congenital primary aphakia (HP:0007707) | 2.15089063 |
123 | Gait imbalance (HP:0002141) | 2.15060128 |
124 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.13784973 |
125 | Methylmalonic acidemia (HP:0002912) | 2.13593281 |
126 | Congenital, generalized hypertrichosis (HP:0004540) | 2.13055202 |
127 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.12213112 |
128 | Epidermoid cyst (HP:0200040) | 2.12138071 |
129 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.11982807 |
130 | Bile duct proliferation (HP:0001408) | 2.11752505 |
131 | Abnormal biliary tract physiology (HP:0012439) | 2.11752505 |
132 | Hyperphosphaturia (HP:0003109) | 2.11026040 |
133 | Methylmalonic aciduria (HP:0012120) | 2.10735518 |
134 | Furrowed tongue (HP:0000221) | 2.06647847 |
135 | Renal tubular dysfunction (HP:0000124) | 2.06508025 |
136 | Occipital encephalocele (HP:0002085) | 2.06464999 |
137 | Dehydration (HP:0001944) | 2.06103936 |
138 | Vacuolated lymphocytes (HP:0001922) | 2.05678343 |
139 | Abnormality of alkaline phosphatase activity (HP:0004379) | 2.05277670 |
140 | Stenosis of the external auditory canal (HP:0000402) | 2.05039789 |
141 | Genital tract atresia (HP:0001827) | 2.04113799 |
142 | Fibular hypoplasia (HP:0003038) | 2.03472516 |
143 | Male pseudohermaphroditism (HP:0000037) | 2.02797701 |
144 | Confusion (HP:0001289) | 2.02491865 |
145 | Potter facies (HP:0002009) | 2.02351888 |
146 | Facial shape deformation (HP:0011334) | 2.02351888 |
147 | Genetic anticipation (HP:0003743) | 2.02022030 |
148 | Increased CSF lactate (HP:0002490) | 2.01800497 |
149 | Postaxial hand polydactyly (HP:0001162) | 2.01255366 |
150 | Hyperventilation (HP:0002883) | 1.99201033 |
151 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.98820316 |
152 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.98820316 |
153 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.98187361 |
154 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.98105574 |
155 | Preaxial hand polydactyly (HP:0001177) | 1.96650532 |
156 | Delayed epiphyseal ossification (HP:0002663) | 1.95700578 |
157 | Small hand (HP:0200055) | 1.94528912 |
158 | Fair hair (HP:0002286) | 1.92544376 |
159 | Systemic lupus erythematosus (HP:0002725) | 1.92030559 |
160 | Absent/shortened dynein arms (HP:0200106) | 1.91963682 |
161 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.91963682 |
162 | Nephrogenic diabetes insipidus (HP:0009806) | 1.91862647 |
163 | Vaginal atresia (HP:0000148) | 1.91735481 |
164 | Elevated alkaline phosphatase (HP:0003155) | 1.91263724 |
165 | Mitral stenosis (HP:0001718) | 1.90841590 |
166 | Nausea (HP:0002018) | 1.90033995 |
167 | Tubulointerstitial fibrosis (HP:0005576) | 1.89510221 |
168 | Aplasia/Hypoplasia of the fibula (HP:0006492) | 1.88673989 |
169 | Progressive cerebellar ataxia (HP:0002073) | 1.88188226 |
170 | Metaphyseal irregularity (HP:0003025) | 1.87553285 |
171 | Asplenia (HP:0001746) | 1.87414402 |
172 | Abnormality of Sharpey fibers (HP:0100685) | 1.86279297 |
173 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.82154449 |
174 | Optic disc pallor (HP:0000543) | 1.80385278 |
175 | Malnutrition (HP:0004395) | 1.79636127 |
176 | Rib fusion (HP:0000902) | 1.78261611 |
177 | Chondrocalcinosis (HP:0000934) | 1.78104577 |
178 | Abnormality of renal resorption (HP:0011038) | 1.76910250 |
179 | Hemiparesis (HP:0001269) | 1.74537417 |
180 | Inability to walk (HP:0002540) | 1.72944720 |
181 | Hepatocellular necrosis (HP:0001404) | 1.72359080 |
182 | Dandy-Walker malformation (HP:0001305) | 1.72098821 |
183 | Broad-based gait (HP:0002136) | 1.71909742 |
184 | Narrow forehead (HP:0000341) | 1.71907901 |
185 | Median cleft lip (HP:0000161) | 1.71110985 |
186 | Abnormality of the renal collecting system (HP:0004742) | 1.70166140 |
187 | Short 4th metacarpal (HP:0010044) | 1.66651608 |
188 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.66651608 |
189 | Cerebellar dysplasia (HP:0007033) | 1.65001667 |
190 | Gaze-evoked nystagmus (HP:0000640) | 1.64816447 |
191 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.64122991 |
192 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.64118482 |
193 | Large for gestational age (HP:0001520) | 1.63817718 |
Rank | Gene Set | Z-score |
---|---|---|
1 | WNK3 | 5.79838956 |
2 | WNK4 | 5.60258087 |
3 | OXSR1 | 5.23086903 |
4 | STK38L | 3.91824366 |
5 | BMPR1B | 2.93338441 |
6 | MAP4K2 | 2.79790941 |
7 | BCKDK | 2.61445599 |
8 | STK39 | 2.56591025 |
9 | INSRR | 2.44376737 |
10 | IRAK3 | 2.09398642 |
11 | MAP3K14 | 2.00268109 |
12 | CASK | 1.90580920 |
13 | LATS1 | 1.90188273 |
14 | TLK1 | 1.85952406 |
15 | MAP3K4 | 1.77326406 |
16 | SGK2 | 1.75819126 |
17 | SGK494 | 1.72962906 |
18 | SGK223 | 1.72962906 |
19 | PINK1 | 1.70626613 |
20 | TIE1 | 1.68953437 |
21 | MST1R | 1.63613295 |
22 | EPHA3 | 1.58510818 |
23 | TGFBR2 | 1.58092434 |
24 | FRK | 1.56305344 |
25 | FGFR4 | 1.52296886 |
26 | TGFBR1 | 1.50837477 |
27 | STK16 | 1.45881508 |
28 | ZAK | 1.45439365 |
29 | EIF2AK2 | 1.45188278 |
30 | ERBB4 | 1.39954667 |
31 | PAK3 | 1.31900509 |
32 | DYRK2 | 1.29150326 |
33 | PIK3CG | 1.28459604 |
34 | NUAK1 | 1.28418122 |
35 | TXK | 1.27038527 |
36 | SGK3 | 1.25441926 |
37 | PLK2 | 1.17775442 |
38 | TAOK3 | 1.13604014 |
39 | TNIK | 1.11843904 |
40 | IRAK1 | 1.09142966 |
41 | NTRK3 | 1.08708521 |
42 | PTK2B | 1.05267065 |
43 | GRK1 | 1.04814348 |
44 | ADRBK1 | 1.01838989 |
45 | MAPK13 | 0.99079225 |
46 | EPHA4 | 0.97487504 |
47 | CSNK1G1 | 0.95608220 |
48 | FGFR2 | 0.93720089 |
49 | WNK1 | 0.93047568 |
50 | MKNK2 | 0.92562370 |
51 | PRKAA2 | 0.91590948 |
52 | MARK1 | 0.89541233 |
53 | STK3 | 0.88840494 |
54 | DYRK3 | 0.88778466 |
55 | ACVR1B | 0.88192302 |
56 | MAPK11 | 0.86555273 |
57 | NEK9 | 0.81644104 |
58 | CSNK1G3 | 0.77100782 |
59 | CSNK1G2 | 0.76758619 |
60 | SIK1 | 0.76749441 |
61 | NME1 | 0.76636668 |
62 | AKT3 | 0.76559460 |
63 | JAK1 | 0.75949766 |
64 | PNCK | 0.74392090 |
65 | IRAK2 | 0.74010576 |
66 | FLT3 | 0.73817924 |
67 | STK38 | 0.73533702 |
68 | ADRBK2 | 0.73007476 |
69 | STK24 | 0.71855226 |
70 | PRKCG | 0.70764468 |
71 | VRK1 | 0.69765498 |
72 | PDK2 | 0.67273546 |
73 | IRAK4 | 0.67178489 |
74 | CAMKK2 | 0.67036166 |
75 | CSNK1A1L | 0.66837510 |
76 | PLK3 | 0.66111120 |
77 | BMPR2 | 0.65423537 |
78 | MAP3K7 | 0.64012895 |
79 | PDK4 | 0.63567471 |
80 | PDK3 | 0.63567471 |
81 | SGK1 | 0.63531895 |
82 | KDR | 0.63190289 |
83 | NTRK2 | 0.62798226 |
84 | PRKAA1 | 0.61945077 |
85 | MAP2K7 | 0.61742655 |
86 | TAF1 | 0.59716162 |
87 | LIMK1 | 0.57710666 |
88 | CAMK2A | 0.55837835 |
89 | TEC | 0.55714270 |
90 | YES1 | 0.55450909 |
91 | MAP3K3 | 0.55156701 |
92 | PRPF4B | 0.54887795 |
93 | EPHB2 | 0.54593719 |
94 | RPS6KA5 | 0.53996778 |
95 | TAOK2 | 0.53391871 |
96 | TRIM28 | 0.53285182 |
97 | CDC7 | 0.53093654 |
98 | GSK3A | 0.52361593 |
99 | MUSK | 0.51902920 |
100 | TRPM7 | 0.51399069 |
101 | EIF2AK3 | 0.50701231 |
102 | PRKCE | 0.50370513 |
103 | IKBKE | 0.50333216 |
104 | CAMK1 | 0.49982192 |
105 | PKN1 | 0.49887661 |
106 | CHEK2 | 0.49298991 |
107 | CSNK1A1 | 0.48933343 |
108 | PLK4 | 0.47644821 |
109 | PRKD2 | 0.47412707 |
110 | ERBB2 | 0.47091160 |
111 | PBK | 0.47090499 |
112 | ABL2 | 0.46429476 |
113 | MYLK | 0.46036313 |
114 | RPS6KA4 | 0.45831497 |
115 | ERBB3 | 0.45236151 |
116 | CAMK1D | 0.45192814 |
117 | PIK3CA | 0.44715911 |
118 | PLK1 | 0.44658307 |
119 | WEE1 | 0.43230965 |
120 | ERN1 | 0.42842356 |
121 | BUB1 | 0.42170194 |
122 | CHUK | 0.42065154 |
123 | BRSK2 | 0.41840183 |
124 | CAMK2D | 0.40866579 |
125 | NLK | 0.38019948 |
126 | DYRK1A | 0.37508085 |
127 | CLK1 | 0.37247306 |
128 | VRK2 | 0.37240816 |
129 | SIK3 | 0.36945468 |
130 | EPHA2 | 0.36643701 |
131 | PRKCD | 0.36611553 |
132 | TBK1 | 0.36189196 |
133 | NEK6 | 0.36127254 |
134 | CDK8 | 0.36047578 |
135 | PRKCZ | 0.35689879 |
136 | IKBKB | 0.35094115 |
137 | FER | 0.35024000 |
138 | MAPK15 | 0.34858194 |
139 | MST4 | 0.34817232 |
140 | MAPK7 | 0.34014942 |
141 | IGF1R | 0.32647691 |
142 | AKT2 | 0.31583044 |
143 | CDK3 | 0.31122043 |
144 | PRKACG | 0.31024353 |
145 | MAP2K6 | 0.30821952 |
146 | JAK3 | 0.30538013 |
147 | TYK2 | 0.30448903 |
148 | PRKCQ | 0.29758719 |
149 | GRK7 | 0.29686521 |
150 | MKNK1 | 0.29453167 |
151 | PRKCA | 0.29234782 |
152 | BCR | 0.29163106 |
153 | MET | 0.29139893 |
154 | PRKCH | 0.28570600 |
155 | RIPK1 | 0.28218667 |
156 | PRKACA | 0.27456897 |
157 | DAPK2 | 0.26881020 |
158 | OBSCN | 0.26313459 |
159 | MAP2K4 | 0.26229596 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 3.48405311 |
2 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 3.26429923 |
3 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 3.02517196 |
4 | Tryptophan metabolism_Homo sapiens_hsa00380 | 2.92913618 |
5 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.88218895 |
6 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.84652123 |
7 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.76980597 |
8 | Phototransduction_Homo sapiens_hsa04744 | 2.75997374 |
9 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.60477820 |
10 | Peroxisome_Homo sapiens_hsa04146 | 2.60406400 |
11 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.55837744 |
12 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.47186374 |
13 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.37566196 |
14 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.36708272 |
15 | Protein export_Homo sapiens_hsa03060 | 2.30106965 |
16 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.29263262 |
17 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 2.21572320 |
18 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.21507331 |
19 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 2.16785705 |
20 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 2.16643577 |
21 | Arginine biosynthesis_Homo sapiens_hsa00220 | 2.02100800 |
22 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.01657891 |
23 | Parkinsons disease_Homo sapiens_hsa05012 | 2.01106369 |
24 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.97030639 |
25 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.95805988 |
26 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.95519176 |
27 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.92870549 |
28 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.89038605 |
29 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.86577105 |
30 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.86372251 |
31 | RNA polymerase_Homo sapiens_hsa03020 | 1.85633498 |
32 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.81907324 |
33 | Histidine metabolism_Homo sapiens_hsa00340 | 1.81048358 |
34 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.78062831 |
35 | Retinol metabolism_Homo sapiens_hsa00830 | 1.73995001 |
36 | Nicotine addiction_Homo sapiens_hsa05033 | 1.67665822 |
37 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.67468177 |
38 | Homologous recombination_Homo sapiens_hsa03440 | 1.66601872 |
39 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.65152261 |
40 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.62197343 |
41 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.57901748 |
42 | Huntingtons disease_Homo sapiens_hsa05016 | 1.57757093 |
43 | Ribosome_Homo sapiens_hsa03010 | 1.56499682 |
44 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.55810244 |
45 | Bile secretion_Homo sapiens_hsa04976 | 1.53704682 |
46 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.53395842 |
47 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.50812357 |
48 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.49549408 |
49 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.44707958 |
50 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.44422395 |
51 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.42314247 |
52 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.41934008 |
53 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.37351640 |
54 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.37169186 |
55 | Basal transcription factors_Homo sapiens_hsa03022 | 1.35704444 |
56 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.33818411 |
57 | Alzheimers disease_Homo sapiens_hsa05010 | 1.32988499 |
58 | Lysine degradation_Homo sapiens_hsa00310 | 1.28159435 |
59 | Morphine addiction_Homo sapiens_hsa05032 | 1.27679042 |
60 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.27672663 |
61 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.23513843 |
62 | Proteasome_Homo sapiens_hsa03050 | 1.22878349 |
63 | Taste transduction_Homo sapiens_hsa04742 | 1.20302543 |
64 | ABC transporters_Homo sapiens_hsa02010 | 1.19687060 |
65 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.17185969 |
66 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.15881459 |
67 | RNA degradation_Homo sapiens_hsa03018 | 1.15841748 |
68 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.14776989 |
69 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.12927051 |
70 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.12317518 |
71 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.05315392 |
72 | Olfactory transduction_Homo sapiens_hsa04740 | 1.04818348 |
73 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.04160382 |
74 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.03313274 |
75 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.00633932 |
76 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.98932999 |
77 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.95172861 |
78 | Carbon metabolism_Homo sapiens_hsa01200 | 0.92396230 |
79 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.92256906 |
80 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.90798399 |
81 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.88699910 |
82 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.88533971 |
83 | GABAergic synapse_Homo sapiens_hsa04727 | 0.83530190 |
84 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.83427431 |
85 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.77782077 |
86 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.76088943 |
87 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.73031701 |
88 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.72884882 |
89 | Circadian entrainment_Homo sapiens_hsa04713 | 0.71400792 |
90 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.70764378 |
91 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.70455515 |
92 | Mineral absorption_Homo sapiens_hsa04978 | 0.68055249 |
93 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.67164616 |
94 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.66429634 |
95 | Purine metabolism_Homo sapiens_hsa00230 | 0.66354715 |
96 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.65741542 |
97 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.62888669 |
98 | Insulin secretion_Homo sapiens_hsa04911 | 0.62533687 |
99 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.61320748 |
100 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.60305789 |
101 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.57499627 |
102 | Circadian rhythm_Homo sapiens_hsa04710 | 0.57135344 |
103 | Metabolic pathways_Homo sapiens_hsa01100 | 0.57045747 |
104 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.56382912 |
105 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.56202756 |
106 | Other glycan degradation_Homo sapiens_hsa00511 | 0.54424840 |
107 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.52206773 |
108 | Melanoma_Homo sapiens_hsa05218 | 0.47951917 |
109 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.47821344 |
110 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.46700001 |
111 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.46371337 |
112 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.45397748 |
113 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.44798142 |
114 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.43940221 |
115 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.42878447 |
116 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.38474338 |
117 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.34543030 |
118 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.30494286 |
119 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.29741123 |
120 | Sulfur relay system_Homo sapiens_hsa04122 | 0.25757016 |
121 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.25529164 |
122 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.22620354 |
123 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.21645272 |
124 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.20308133 |
125 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.16293659 |
126 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.16273522 |
127 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.15260698 |
128 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.14071177 |
129 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.13918463 |
130 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.13388177 |
131 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.12990905 |
132 | Lysosome_Homo sapiens_hsa04142 | 0.10017025 |
133 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.09014473 |
134 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.08794096 |
135 | Hepatitis C_Homo sapiens_hsa05160 | 0.06787530 |
136 | Malaria_Homo sapiens_hsa05144 | 0.06241816 |
137 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.05633658 |
138 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.03953324 |
139 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.03372045 |
140 | Phagosome_Homo sapiens_hsa04145 | 0.03168822 |
141 | Galactose metabolism_Homo sapiens_hsa00052 | 0.03002494 |
142 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.02373561 |
143 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.01556781 |
144 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | -0.0236064 |
145 | Regulation of autophagy_Homo sapiens_hsa04140 | -0.0198342 |
146 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | -0.0095027 |