NPDC1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.08827211
2synaptic vesicle maturation (GO:0016188)4.82503718
3positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.70222901
4synaptic vesicle exocytosis (GO:0016079)4.58143004
5locomotory exploration behavior (GO:0035641)4.45434387
6vocalization behavior (GO:0071625)4.44844474
7glutamate secretion (GO:0014047)4.36764709
8regulation of synaptic vesicle exocytosis (GO:2000300)4.33851852
9neuron cell-cell adhesion (GO:0007158)4.24222742
10regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.16796269
11protein localization to synapse (GO:0035418)4.13986354
12positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.04970752
13neuronal action potential propagation (GO:0019227)3.86309731
14regulation of glutamate receptor signaling pathway (GO:1900449)3.84431648
15regulation of synaptic vesicle transport (GO:1902803)3.83671453
16layer formation in cerebral cortex (GO:0021819)3.81688046
17exploration behavior (GO:0035640)3.79884524
18synaptic vesicle docking involved in exocytosis (GO:0016081)3.76864222
19negative regulation of cell size (GO:0045792)3.67106210
20neuron recognition (GO:0008038)3.65865269
21ionotropic glutamate receptor signaling pathway (GO:0035235)3.64742132
22cerebellar granule cell differentiation (GO:0021707)3.63597329
23regulation of neuronal synaptic plasticity (GO:0048168)3.61667967
24neurotransmitter secretion (GO:0007269)3.54757458
25axonal fasciculation (GO:0007413)3.53762561
26peptidyl-tyrosine autophosphorylation (GO:0038083)3.49266645
27regulation of synapse structural plasticity (GO:0051823)3.47973732
28synaptic transmission, glutamatergic (GO:0035249)3.41129028
29proline transport (GO:0015824)3.40954189
30glutamate receptor signaling pathway (GO:0007215)3.40300229
31regulation of long-term neuronal synaptic plasticity (GO:0048169)3.37637510
32dendritic spine morphogenesis (GO:0060997)3.36637334
33positive regulation of synapse maturation (GO:0090129)3.32355943
34cellular potassium ion homeostasis (GO:0030007)3.28151416
35semaphorin-plexin signaling pathway (GO:0071526)3.25699238
36regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.23950718
37response to pheromone (GO:0019236)3.23159979
38cytoskeletal anchoring at plasma membrane (GO:0007016)3.21578594
39cell communication by electrical coupling (GO:0010644)3.19545151
40detection of calcium ion (GO:0005513)3.18926836
41cell migration in hindbrain (GO:0021535)3.18628183
42activation of protein kinase A activity (GO:0034199)3.17825052
43dendrite morphogenesis (GO:0048813)3.17162064
44negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.16898408
45innervation (GO:0060384)3.16419982
46protein retention in ER lumen (GO:0006621)3.16145343
47establishment of mitochondrion localization (GO:0051654)3.15179442
48neuron-neuron synaptic transmission (GO:0007270)3.14266704
49regulation of vesicle fusion (GO:0031338)3.11214214
50negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)3.10901250
51G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.08974879
52cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.08538221
53positive regulation of synaptic transmission, GABAergic (GO:0032230)3.07415068
54postsynaptic membrane organization (GO:0001941)3.06843943
55neuromuscular process controlling posture (GO:0050884)3.04493343
56neurotransmitter-gated ion channel clustering (GO:0072578)3.03810278
57membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.01987293
58positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.00383901
59long-term memory (GO:0007616)2.99974459
60potassium ion homeostasis (GO:0055075)2.99884552
61positive regulation of membrane potential (GO:0045838)2.98562973
62synaptic vesicle endocytosis (GO:0048488)2.97392445
63regulation of excitatory postsynaptic membrane potential (GO:0060079)2.96555135
64regulation of neurotransmitter secretion (GO:0046928)2.95543271
65cell-cell junction maintenance (GO:0045217)2.95506806
66sodium ion export (GO:0071436)2.95481879
67transmission of nerve impulse (GO:0019226)2.95233511
68mating behavior (GO:0007617)2.95021769
69neurotransmitter transport (GO:0006836)2.93970762
70regulation of synaptic plasticity (GO:0048167)2.93554247
71negative regulation of microtubule polymerization (GO:0031115)2.90808873
72cerebellar Purkinje cell differentiation (GO:0021702)2.90585365
73regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.89664382
74long-term synaptic potentiation (GO:0060291)2.89274497
75mitochondrion transport along microtubule (GO:0047497)2.89177785
76establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.89177785
77response to auditory stimulus (GO:0010996)2.88568205
78regulation of ARF protein signal transduction (GO:0032012)2.87254047
79regulation of postsynaptic membrane potential (GO:0060078)2.85769667
80regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.84585491
81axon ensheathment in central nervous system (GO:0032291)2.84419826
82central nervous system myelination (GO:0022010)2.84419826
83membrane depolarization during action potential (GO:0086010)2.84171146
84gamma-aminobutyric acid transport (GO:0015812)2.83133224
85positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.82563086
86cerebellar Purkinje cell layer development (GO:0021680)2.80904063
87synapse assembly (GO:0007416)2.78853000
88regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.77391087
89neuromuscular process controlling balance (GO:0050885)2.77056817
90maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.75841944
91gamma-aminobutyric acid signaling pathway (GO:0007214)2.75569687
92positive regulation of dendritic spine development (GO:0060999)2.73154946
93regulation of amyloid precursor protein catabolic process (GO:1902991)2.72877515
94neuronal ion channel clustering (GO:0045161)2.72833849
95dendritic spine organization (GO:0097061)2.72446438
96regulation of synaptic transmission, glutamatergic (GO:0051966)2.71072615
97positive regulation of dendrite development (GO:1900006)2.71047253
98endothelial cell chemotaxis (GO:0035767)2.71009365
99regulation of neurotransmitter transport (GO:0051588)2.69880601
100adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.68479757
101regulation of dendritic spine morphogenesis (GO:0061001)2.67717584
102dopamine receptor signaling pathway (GO:0007212)2.66937988
103auditory behavior (GO:0031223)2.66926674
104positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.66361817
105membrane depolarization (GO:0051899)2.66243078
106regulation of neurotransmitter levels (GO:0001505)2.65674264
107retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.65479556
108G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.65272571
109amino acid import (GO:0043090)2.65090166
110synapse organization (GO:0050808)2.64734890
111negative regulation of synaptic transmission, GABAergic (GO:0032229)2.63933648
112positive regulation of potassium ion transmembrane transport (GO:1901381)2.63160033
113synaptic transmission (GO:0007268)2.61079229
114presynaptic membrane assembly (GO:0097105)2.60620281
115neuromuscular synaptic transmission (GO:0007274)2.60454529
116regulation of ARF GTPase activity (GO:0032312)2.58773529
117positive regulation of synapse assembly (GO:0051965)2.58701591
118regulation of synapse maturation (GO:0090128)2.58236443
119regulation of synaptic transmission (GO:0050804)2.57728583
120calcium-mediated signaling using intracellular calcium source (GO:0035584)2.57412151
121neuronal action potential (GO:0019228)2.56564671
122presynaptic membrane organization (GO:0097090)2.55946618
123glycine transport (GO:0015816)2.55763948
124vesicle transport along microtubule (GO:0047496)2.53145585
125L-amino acid import (GO:0043092)2.47764839
126myelin maintenance (GO:0043217)2.43486497
127mannose metabolic process (GO:0006013)2.41832156
128regulation of female receptivity (GO:0045924)2.38674730
129collecting duct development (GO:0072044)2.36755939
130positive regulation of neurotransmitter transport (GO:0051590)2.36158262
131cell junction maintenance (GO:0034331)2.32158916
132cellular response to catecholamine stimulus (GO:0071870)2.28786107
133cellular response to monoamine stimulus (GO:0071868)2.28786107
134dicarboxylic acid transport (GO:0006835)2.27879428
135axon extension (GO:0048675)2.24233365
136regulation of respiratory system process (GO:0044065)2.23523096
137negative regulation of catenin import into nucleus (GO:0035414)2.22899359
138chondroitin sulfate catabolic process (GO:0030207)2.22762675
139COPI coating of Golgi vesicle (GO:0048205)2.21961419
140Golgi transport vesicle coating (GO:0048200)2.21961419
141establishment of synaptic vesicle localization (GO:0097480)2.21632792
142synaptic vesicle transport (GO:0048489)2.21632792

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.48553765
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.63811329
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.15585904
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.08139657
5JARID2_20064375_ChIP-Seq_MESCs_Mouse3.01445690
6GBX2_23144817_ChIP-Seq_PC3_Human2.96150972
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.84649167
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.84649167
9* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.83781744
10* LXR_22292898_ChIP-Seq_THP-1_Human2.75925749
11SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.67734081
12SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.67557316
13SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.66092464
14EZH2_27304074_Chip-Seq_ESCs_Mouse2.64765528
15* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.61010191
16* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.58454428
17EED_16625203_ChIP-ChIP_MESCs_Mouse2.56223904
18* REST_21632747_ChIP-Seq_MESCs_Mouse2.50038854
19EZH2_27294783_Chip-Seq_ESCs_Mouse2.45619029
20ESR2_21235772_ChIP-Seq_MCF-7_Human2.44232169
21* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.37898253
22DROSHA_22980978_ChIP-Seq_HELA_Human2.28757363
23RNF2_27304074_Chip-Seq_ESCs_Mouse2.25663648
24CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.22864912
25RARG_19884340_ChIP-ChIP_MEFs_Mouse2.22833350
26TP63_17297297_ChIP-ChIP_HaCaT_Human2.20249053
27KDM2B_26808549_Chip-Seq_SUP-B15_Human2.18524127
28RARB_27405468_Chip-Seq_BRAIN_Mouse2.11762467
29RACK7_27058665_Chip-Seq_MCF-7_Human2.11335632
30* REST_18959480_ChIP-ChIP_MESCs_Mouse2.09713166
31NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.07614852
32IKZF1_21737484_ChIP-ChIP_HCT116_Human2.05282812
33P68_20966046_ChIP-Seq_HELA_Human1.82809703
34* TET1_21451524_ChIP-Seq_MESCs_Mouse1.80739305
35EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.72995258
36ERG_21242973_ChIP-ChIP_JURKAT_Human1.72742030
37KDM2B_26808549_Chip-Seq_DND41_Human1.72227674
38ELK3_25401928_ChIP-Seq_HUVEC_Human1.70907844
39SMC4_20622854_ChIP-Seq_HELA_Human1.69875294
40KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.68522337
41MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.66148023
42PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.65646431
43CREB1_26743006_Chip-Seq_LNCaP_Human1.62583842
44ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.61439639
45SRY_22984422_ChIP-ChIP_TESTIS_Rat1.55711332
46ZNF263_19887448_ChIP-Seq_K562_Human1.54995178
47CTBP2_25329375_ChIP-Seq_LNCAP_Human1.54612887
48PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.54560784
49ESR1_21235772_ChIP-Seq_MCF-7_Human1.54547275
50SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.53157528
51ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.52424264
52GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.52186747
53ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.50424809
54UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.49770313
55AR_21572438_ChIP-Seq_LNCaP_Human1.49592059
56BMI1_23680149_ChIP-Seq_NPCS_Mouse1.45906841
57ZFP281_27345836_Chip-Seq_ESCs_Mouse1.45811222
58ZNF274_21170338_ChIP-Seq_K562_Hela1.45810528
59SA1_27219007_Chip-Seq_ERYTHROID_Human1.42624065
60CTBP1_25329375_ChIP-Seq_LNCAP_Human1.41059189
61* RING1B_27294783_Chip-Seq_ESCs_Mouse1.40996548
62TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.40011328
63CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.39479755
64RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.38410381
65PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.34299788
66CTCF_27219007_Chip-Seq_ERYTHROID_Human1.34118164
67SMAD4_21799915_ChIP-Seq_A2780_Human1.32988687
68TCF7_22412390_ChIP-Seq_EML_Mouse1.32420116
69NR3C1_23031785_ChIP-Seq_PC12_Mouse1.31541729
70CBX2_27304074_Chip-Seq_ESCs_Mouse1.28644139
71MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.27079000
72VDR_21846776_ChIP-Seq_THP-1_Human1.24222598
73KDM2B_26808549_Chip-Seq_JURKAT_Human1.22097987
74ESR1_15608294_ChIP-ChIP_MCF-7_Human1.21487673
75RUNX1_27514584_Chip-Seq_MCF-7_Human1.20364465
76TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.20061726
77DNAJC2_21179169_ChIP-ChIP_NT2_Human1.19449153
78RING1B_27294783_Chip-Seq_NPCs_Mouse1.19356368
79* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.18055230
80TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.17594506
81* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.17241756
82* KDM2B_26808549_Chip-Seq_K562_Human1.16642001
83TAF15_26573619_Chip-Seq_HEK293_Human1.16344851
84SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.15694593
85OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.15101931
86EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.14271818
87CDX2_19796622_ChIP-Seq_MESCs_Mouse1.14247769
88ELF1_20517297_ChIP-Seq_JURKAT_Human1.13657364
89SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.13365719
90WT1_25993318_ChIP-Seq_PODOCYTE_Human1.13273006
91* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.11595907
92TOP2B_26459242_ChIP-Seq_MCF-7_Human1.11591458
93SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.10298642
94TP63_22573176_ChIP-Seq_HFKS_Human1.09832572
95PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.09730913
96CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.08900690
97SOX2_21211035_ChIP-Seq_LN229_Gbm1.08555737
98P300_19829295_ChIP-Seq_ESCs_Human1.07885370
99TP53_20018659_ChIP-ChIP_R1E_Mouse1.07785080
100ZFP57_27257070_Chip-Seq_ESCs_Mouse1.07394665
101SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.07314780
102AR_19668381_ChIP-Seq_PC3_Human1.05806153
103AHR_22903824_ChIP-Seq_MCF-7_Human1.05395314
104SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.04713636
105RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.04633501
106* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.04534947
107AR_25329375_ChIP-Seq_VCAP_Human1.04445408
108PIAS1_25552417_ChIP-Seq_VCAP_Human1.03894042
109* SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.03741269
110NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.03569231
111CTCF_27219007_Chip-Seq_Bcells_Human1.03318407
112OCT4_19829295_ChIP-Seq_ESCs_Human1.03137056
113ESR1_20079471_ChIP-ChIP_T-47D_Human1.02736586
114STAT6_21828071_ChIP-Seq_BEAS2B_Human1.02310484
115OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.02227840
116SMAD3_21741376_ChIP-Seq_EPCs_Human1.01883573
117* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.01602813
118RNF2_27304074_Chip-Seq_NSC_Mouse1.01577219
119ZNF217_24962896_ChIP-Seq_MCF-7_Human1.01359670
120ARNT_22903824_ChIP-Seq_MCF-7_Human1.00579211
121TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.00471487
122SA1_27219007_Chip-Seq_Bcells_Human0.99815669
123ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.99241513
124BCL6_27268052_Chip-Seq_Bcells_Human0.98325448
125TP53_22127205_ChIP-Seq_IMR90_Human0.97567820
126* CTCF_18555785_ChIP-Seq_MESCs_Mouse0.96874152
127PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.96372148
128* GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.96349882
129P300_27058665_Chip-Seq_ZR-75-30cells_Human0.96317975
130TET1_21490601_ChIP-Seq_MESCs_Mouse0.96282200
131STAT3_23295773_ChIP-Seq_U87_Human0.93143063
132IGF1R_20145208_ChIP-Seq_DFB_Human0.92677485
133SMAD3_21741376_ChIP-Seq_ESCs_Human0.92548002
134ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.92432902
135P53_22127205_ChIP-Seq_FIBROBLAST_Human0.91987343
136YAP1_20516196_ChIP-Seq_MESCs_Mouse0.90686453
137SMAD4_21741376_ChIP-Seq_HESCs_Human0.88697221
138MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.87604047
139TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.86229906
140NR3C1_21868756_ChIP-Seq_MCF10A_Human0.85768600
141ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.84988002
142VDR_22108803_ChIP-Seq_LS180_Human0.84371579
143RUNX2_22187159_ChIP-Seq_PCA_Human0.84329043
144THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.82748842
145TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.81531669
146EP300_21415370_ChIP-Seq_HL-1_Mouse0.80882966
147PRDM14_20953172_ChIP-Seq_ESCs_Human0.79185598
148TCF4_23295773_ChIP-Seq_U87_Human0.77057659
149TRIM28_21343339_ChIP-Seq_HEK293_Human0.76585397
150TP53_18474530_ChIP-ChIP_U2OS_Human0.75733153
151JUN_21703547_ChIP-Seq_K562_Human0.75416022
152AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.75092904
153SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.73704679
154SMAD3_21741376_ChIP-Seq_HESCs_Human0.73475015

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.39272307
2MP0003880_abnormal_central_pattern4.10265079
3MP0004270_analgesia3.62611983
4MP0003635_abnormal_synaptic_transmissio3.57927374
5MP0001968_abnormal_touch/_nociception3.06293047
6MP0002063_abnormal_learning/memory/cond2.82017888
7MP0009745_abnormal_behavioral_response2.77466936
8MP0004858_abnormal_nervous_system2.69408453
9MP0005423_abnormal_somatic_nervous2.69195950
10MP0002734_abnormal_mechanical_nocicepti2.67961322
11MP0002735_abnormal_chemical_nociception2.61344398
12MP0002064_seizures2.57969169
13MP0002736_abnormal_nociception_after2.53400169
14MP0003705_abnormal_hypodermis_morpholog2.48399038
15MP0002572_abnormal_emotion/affect_behav2.38922999
16MP0006276_abnormal_autonomic_nervous2.37244323
17MP0002733_abnormal_thermal_nociception2.36825733
18MP0002272_abnormal_nervous_system2.32773081
19MP0009046_muscle_twitch2.30372687
20MP0002249_abnormal_larynx_morphology2.25217857
21MP0001970_abnormal_pain_threshold2.12745566
22MP0005409_darkened_coat_color2.08588455
23MP0002184_abnormal_innervation2.07007688
24MP0001486_abnormal_startle_reflex2.05975532
25MP0001984_abnormal_olfaction2.04996185
26MP0000778_abnormal_nervous_system2.03842827
27MP0003123_paternal_imprinting2.03144773
28MP0001440_abnormal_grooming_behavior2.01083414
29MP0003329_amyloid_beta_deposits1.97651143
30MP0005645_abnormal_hypothalamus_physiol1.95679688
31MP0009780_abnormal_chondrocyte_physiolo1.91817545
32MP0002909_abnormal_adrenal_gland1.84300735
33MP0002067_abnormal_sensory_capabilities1.83290269
34MP0001501_abnormal_sleep_pattern1.82822264
35MP0000678_abnormal_parathyroid_gland1.70389597
36MP0002557_abnormal_social/conspecific_i1.69968257
37MP0003122_maternal_imprinting1.64212365
38MP0009384_cardiac_valve_regurgitation1.63166122
39MP0000955_abnormal_spinal_cord1.62766691
40MP0004811_abnormal_neuron_physiology1.61705955
41MP0002822_catalepsy1.59643694
42MP0008569_lethality_at_weaning1.54677850
43MP0005646_abnormal_pituitary_gland1.48311437
44MP0010386_abnormal_urinary_bladder1.47853234
45MP0002882_abnormal_neuron_morphology1.47723844
46MP0000013_abnormal_adipose_tissue1.44522917
47MP0010234_abnormal_vibrissa_follicle1.44517414
48MP0001849_ear_inflammation1.44012812
49MP0001502_abnormal_circadian_rhythm1.41426853
50MP0005386_behavior/neurological_phenoty1.40599665
51MP0004924_abnormal_behavior1.40599665
52MP0004885_abnormal_endolymph1.31249592
53MP0005670_abnormal_white_adipose1.30072854
54MP0002066_abnormal_motor_capabilities/c1.29315263
55MP0000751_myopathy1.24430880
56MP0003279_aneurysm1.23346878
57MP0003283_abnormal_digestive_organ1.22845738
58MP0001905_abnormal_dopamine_level1.21265197
59MP0005503_abnormal_tendon_morphology1.18331878
60MP0001529_abnormal_vocalization1.16785869
61MP0003879_abnormal_hair_cell1.16286083
62MP0003172_abnormal_lysosome_physiology1.14726893
63MP0000681_abnormal_thyroid_gland1.13241690
64MP0000462_abnormal_digestive_system1.11898643
65MP0005058_abnormal_lysosome_morphology1.09967146
66MP0004142_abnormal_muscle_tone1.09766598
67MP0002152_abnormal_brain_morphology1.09465632
68MP0004145_abnormal_muscle_electrophysio1.07781102
69MP0000537_abnormal_urethra_morphology1.05232490
70MP0003633_abnormal_nervous_system1.05077602
71MP0003634_abnormal_glial_cell1.03254920
72MP0000579_abnormal_nail_morphology1.02809898
73MP0003690_abnormal_glial_cell1.02721136
74MP0002837_dystrophic_cardiac_calcinosis0.99763157
75MP0003942_abnormal_urinary_system0.95884953
76MP0003631_nervous_system_phenotype0.95154263
77MP0004742_abnormal_vestibular_system0.95055039
78MP0002069_abnormal_eating/drinking_beha0.94609929
79MP0000631_abnormal_neuroendocrine_gland0.94026930
80MP0009379_abnormal_foot_pigmentation0.93988635
81MP0002752_abnormal_somatic_nervous0.93466343
82MP0001664_abnormal_digestion0.93011117
83MP0002638_abnormal_pupillary_reflex0.91156993
84MP0002229_neurodegeneration0.90906163
85MP0005623_abnormal_meninges_morphology0.90451296
86MP0000566_synostosis0.90053310
87MP0005375_adipose_tissue_phenotype0.89319395
88MP0005394_taste/olfaction_phenotype0.88445454
89MP0005499_abnormal_olfactory_system0.88445454
90MP0001958_emphysema0.88358978
91MP0003787_abnormal_imprinting0.85143750
92MP0001299_abnormal_eye_distance/0.84670491
93MP0001188_hyperpigmentation0.84598719
94MP0002796_impaired_skin_barrier0.80274172
95MP0002751_abnormal_autonomic_nervous0.80007469
96MP0005551_abnormal_eye_electrophysiolog0.79768681
97MP0010368_abnormal_lymphatic_system0.79723875
98MP0001963_abnormal_hearing_physiology0.78697278
99MP0001986_abnormal_taste_sensitivity0.78202021
100MP0004085_abnormal_heartbeat0.77772868
101MP0006072_abnormal_retinal_apoptosis0.76719293
102MP0001485_abnormal_pinna_reflex0.76510310
103MP0001177_atelectasis0.75572677
104MP0005666_abnormal_adipose_tissue0.75214182
105MP0004510_myositis0.73352501
106MP0003632_abnormal_nervous_system0.72798740
107MP0008438_abnormal_cutaneous_collagen0.71638131
108MP0008961_abnormal_basal_metabolism0.71297833
109MP0003183_abnormal_peptide_metabolism0.70924040
110MP0000467_abnormal_esophagus_morphology0.70698312
111MP0002234_abnormal_pharynx_morphology0.70471153
112MP0001348_abnormal_lacrimal_gland0.70303151
113MP0004233_abnormal_muscle_weight0.69729779
114MP0000604_amyloidosis0.68641864
115MP0005167_abnormal_blood-brain_barrier0.68490423
116MP0002932_abnormal_joint_morphology0.68463858
117MP0000003_abnormal_adipose_tissue0.68337180
118MP0000920_abnormal_myelination0.67336259
119MP0002653_abnormal_ependyma_morphology0.67250070
120MP0008874_decreased_physiological_sensi0.67239717
121MP0005535_abnormal_body_temperature0.67070900
122MP0008260_abnormal_autophagy0.66199676
123MP0003861_abnormal_nervous_system0.65284249
124MP0002116_abnormal_craniofacial_bone0.65116423
125MP0000538_abnormal_urinary_bladder0.64943202
126MP0000026_abnormal_inner_ear0.64088160
127MP0000534_abnormal_ureter_morphology0.63716918
128MP0002876_abnormal_thyroid_physiology0.63296672
129MP0003137_abnormal_impulse_conducting0.62418480
130MP0002090_abnormal_vision0.60968038
131MP0004043_abnormal_pH_regulation0.58282313
132MP0001943_abnormal_respiration0.57217298
133MP0008789_abnormal_olfactory_epithelium0.55645675
134MP0004215_abnormal_myocardial_fiber0.53792354
135MP0005187_abnormal_penis_morphology0.53116495

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)5.84281519
2Focal motor seizures (HP:0011153)5.36605126
3Focal seizures (HP:0007359)4.67180187
4Obstructive sleep apnea (HP:0002870)4.66908086
5Visual hallucinations (HP:0002367)4.60429046
6Atonic seizures (HP:0010819)4.19932073
7J-shaped sella turcica (HP:0002680)4.00949335
8Epileptic encephalopathy (HP:0200134)3.86058906
9Supranuclear gaze palsy (HP:0000605)3.72184023
10Progressive cerebellar ataxia (HP:0002073)3.68013357
11Action tremor (HP:0002345)3.57775949
12Ankle clonus (HP:0011448)3.47530294
13Febrile seizures (HP:0002373)3.42555481
14Lymphangioma (HP:0100764)3.28675353
15Absence seizures (HP:0002121)3.26241196
16Distal upper limb amyotrophy (HP:0007149)3.25169747
17Upper limb amyotrophy (HP:0009129)3.25169747
18Hyperacusis (HP:0010780)3.17574060
19Annular pancreas (HP:0001734)3.17431300
20Dialeptic seizures (HP:0011146)2.99417961
21Generalized tonic-clonic seizures (HP:0002069)2.92750875
22Limb dystonia (HP:0002451)2.90637378
23Stridor (HP:0010307)2.88550061
24Amblyopia (HP:0000646)2.86328922
25Broad face (HP:0000283)2.85837407
26Neurofibrillary tangles (HP:0002185)2.84656072
27Spinal canal stenosis (HP:0003416)2.83335306
28Cerebral aneurysm (HP:0004944)2.82904486
29Hand muscle atrophy (HP:0009130)2.81666888
30Cerebral inclusion bodies (HP:0100314)2.77979267
31Cervical subluxation (HP:0003308)2.77162948
32Abnormal eating behavior (HP:0100738)2.77014884
33Truncal ataxia (HP:0002078)2.74263921
34Depression (HP:0000716)2.73984104
35Megalencephaly (HP:0001355)2.71229746
36Thin bony cortex (HP:0002753)2.71087993
37Shallow orbits (HP:0000586)2.70969535
38Retinal dysplasia (HP:0007973)2.66456159
39Anxiety (HP:0000739)2.60866147
40Pheochromocytoma (HP:0002666)2.58810449
41Agitation (HP:0000713)2.56776553
42Failure to thrive in infancy (HP:0001531)2.54769788
43Hypoventilation (HP:0002791)2.51252801
44Polyphagia (HP:0002591)2.47507599
45Mutism (HP:0002300)2.46450750
46Hemiparesis (HP:0001269)2.45953049
47Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.45674385
48Poor eye contact (HP:0000817)2.40961410
49Torticollis (HP:0000473)2.40606742
50Epileptiform EEG discharges (HP:0011182)2.40409387
51Pointed chin (HP:0000307)2.39650438
52Termporal pattern (HP:0011008)2.38486485
53Insidious onset (HP:0003587)2.38486485
54Dysmetria (HP:0001310)2.37172803
55EEG with generalized epileptiform discharges (HP:0011198)2.35665329
56Broad-based gait (HP:0002136)2.34741515
57Broad metatarsal (HP:0001783)2.32596756
58Nuclear cataract (HP:0100018)2.29912102
59Akinesia (HP:0002304)2.28565904
60Protrusio acetabuli (HP:0003179)2.26596883
61Scanning speech (HP:0002168)2.26488208
62Hypsarrhythmia (HP:0002521)2.26292354
63Lower limb asymmetry (HP:0100559)2.25757410
64Mitral regurgitation (HP:0001653)2.24777034
65Growth hormone excess (HP:0000845)2.23681151
66Turricephaly (HP:0000262)2.23384626
67Neuroendocrine neoplasm (HP:0100634)2.22864124
68Hypercortisolism (HP:0001578)2.21893484
69Bronchomalacia (HP:0002780)2.21847933
70Excessive salivation (HP:0003781)2.18747925
71Drooling (HP:0002307)2.18747925
72Focal dystonia (HP:0004373)2.18712962
73Impaired vibration sensation in the lower limbs (HP:0002166)2.17915588
74Dysdiadochokinesis (HP:0002075)2.17399161
75Impaired social interactions (HP:0000735)2.16498855
76Abnormal social behavior (HP:0012433)2.16498855
77Genetic anticipation (HP:0003743)2.15169335
78Spastic gait (HP:0002064)2.13218505
79Ventricular fibrillation (HP:0001663)2.12218324
80Abnormality of the corticospinal tract (HP:0002492)2.08286558
81Lower limb muscle weakness (HP:0007340)2.07641500
82Abnormality of the lower motor neuron (HP:0002366)2.07179991
83Narrow nasal bridge (HP:0000446)2.06886531
84Hyperventilation (HP:0002883)2.06436619
85Deformed sella turcica (HP:0002681)2.06154012
86Urinary bladder sphincter dysfunction (HP:0002839)2.05960191
87Neuronal loss in central nervous system (HP:0002529)2.03891108
88Visceral angiomatosis (HP:0100761)2.02448507
89Atelectasis (HP:0100750)2.02258819
90Urinary urgency (HP:0000012)2.00918090
91Congenital glaucoma (HP:0001087)2.00568548
92Postural instability (HP:0002172)1.98807646
93Craniofacial dystonia (HP:0012179)1.98533353
94Hypoplasia of the brainstem (HP:0002365)1.97891058
95Aplasia/Hypoplasia of the brainstem (HP:0007362)1.97891058
96Mildly elevated creatine phosphokinase (HP:0008180)1.97229996
97Gaze-evoked nystagmus (HP:0000640)1.97048401
98Joint stiffness (HP:0001387)1.96290860
99Insomnia (HP:0100785)1.95427682
100Lower limb amyotrophy (HP:0007210)1.95250344
101Precocious puberty (HP:0000826)1.92972745
102Gait imbalance (HP:0002141)1.92902424
103Achilles tendon contracture (HP:0001771)1.92085547
104Bundle branch block (HP:0011710)1.90014005
105Anosmia (HP:0000458)1.89970802
106Psychosis (HP:0000709)1.88584334
107Progressive inability to walk (HP:0002505)1.88392608
108Rapidly progressive (HP:0003678)1.88133705
109Ulnar claw (HP:0001178)1.87021334
110Distal lower limb amyotrophy (HP:0008944)1.86886462
111Type II lissencephaly (HP:0007260)1.86407206
112Stereotypic behavior (HP:0000733)1.86206485
113Fetal akinesia sequence (HP:0001989)1.85931195
114Elfin facies (HP:0004428)1.84628629
115Testicular atrophy (HP:0000029)1.83642006
116Specific learning disability (HP:0001328)1.83464772
117Mucopolysacchariduria (HP:0008155)1.82438747
118Urinary glycosaminoglycan excretion (HP:0003541)1.82438747
119Hemiplegia (HP:0002301)1.82368902
120Intention tremor (HP:0002080)1.82359169
121Buphthalmos (HP:0000557)1.81042652
122Biconcave vertebral bodies (HP:0004586)1.80878072
123Delusions (HP:0000746)1.80744937
124Aplasia involving bones of the extremities (HP:0009825)1.79593021
125Aplasia involving bones of the upper limbs (HP:0009823)1.79593021
126Aplasia of the phalanges of the hand (HP:0009802)1.79593021
127Abnormal EKG (HP:0003115)1.78122465
128Menstrual irregularities (HP:0000858)1.78017427
129Hemangiomatosis (HP:0007461)1.77575270
130Papilledema (HP:0001085)1.76764028
131Impaired smooth pursuit (HP:0007772)1.76375570
132Bladder diverticulum (HP:0000015)1.76302330
133Abnormality of calcium-phosphate metabolism (HP:0100530)1.76018178
134Diplopia (HP:0000651)1.75999161
135Abnormality of binocular vision (HP:0011514)1.75999161
136Abnormality of mucopolysaccharide metabolism (HP:0011020)1.75018633
137Abnormality of polysaccharide metabolism (HP:0011012)1.75018633
138Abnormality of glycosaminoglycan metabolism (HP:0004371)1.75018633
139Fragile skin (HP:0001030)1.74797411
140Absent speech (HP:0001344)1.74561311
141Bradycardia (HP:0001662)1.73778029
142Apathy (HP:0000741)1.73012335
143Truncus arteriosus (HP:0001660)1.72688697
144Bradykinesia (HP:0002067)1.72604150
145Sleep apnea (HP:0010535)1.71687557
146Hyperthyroidism (HP:0000836)1.71142669
147Diminished motivation (HP:0000745)1.70850344
148Impaired pain sensation (HP:0007328)1.70613577
149Abnormality of pain sensation (HP:0010832)1.70613577
150Aortic regurgitation (HP:0001659)1.70348679
151Prolonged QT interval (HP:0001657)1.70326648
152Atrophic scars (HP:0001075)1.69589368
153Tetraplegia (HP:0002445)1.68951508
154Germ cell neoplasia (HP:0100728)1.68938436
155Distal lower limb muscle weakness (HP:0009053)1.67348454
156Abnormal atrioventricular conduction (HP:0005150)1.67315381
157Exotropia (HP:0000577)1.67100973
158Premature rupture of membranes (HP:0001788)1.67100875
159Hammertoe (HP:0001765)1.67080293
160Enlarged penis (HP:0000040)1.66687185
161Hyperparathyroidism (HP:0000843)1.65434346
162Axonal loss (HP:0003447)1.64181726
163Spinal cord compression (HP:0002176)1.63127102
164Abnormality of the Achilles tendon (HP:0005109)1.63075767
165Neoplasm of the heart (HP:0100544)1.62914496
166Bowel diverticulosis (HP:0005222)1.62397427
167Dysostosis multiplex (HP:0000943)1.62355579
168Hypercalcemia (HP:0003072)1.62292122

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.59206919
2NTRK34.06523683
3EPHA43.36052825
4MAP3K93.31761860
5MARK13.22858635
6SIK12.84193152
7ARAF2.70657960
8MINK12.57523984
9TESK12.31598006
10PKN22.24545474
11PAK62.20456049
12MAP3K42.17089659
13KSR22.15891918
14NTRK12.09666534
15MAP3K122.06397190
16PRKD32.02137058
17DAPK21.99551356
18NTRK21.87054275
19MAP2K71.85573664
20PHKG21.76480220
21PHKG11.76480220
22CASK1.75708847
23MAP3K111.72630507
24EPHA21.71669928
25PRKD21.69680771
26GRK51.69623120
27SMG11.64122777
28MAP3K21.59011320
29MAPK131.54655948
30KSR11.50846596
31CDK51.44506585
32EEF2K1.44395114
33ERN11.43443408
34MAP2K41.41469671
35UHMK11.40571370
36PLK21.38294368
37LMTK21.35102589
38CAMKK11.32957463
39PRPF4B1.31627584
40MAPKAPK31.22815437
41PAK31.19778079
42LATS21.16937472
43PNCK1.15903471
44CAMKK21.15792912
45TNIK1.10617518
46PRKCG1.08780746
47TYRO31.07472203
48RIPK11.04374168
49DAPK11.04290106
50BRAF1.03296400
51CDK190.98040236
52MAP2K60.97703046
53FER0.96804987
54RET0.96380325
55CAMK2A0.94191355
56CDK140.93419805
57SGK4940.93220451
58SGK2230.93220451
59CAMK2B0.92230754
60CDK180.90348715
61STK380.90326785
62DDR20.87911790
63CDK150.87234231
64LIMK10.86430274
65PRKG20.86068696
66MAP3K60.84299369
67RIPK40.83162524
68PTK60.82766453
69PTK2B0.82228504
70MAP3K10.79473610
71MST1R0.79063072
72NME10.78689888
73TIE10.78531862
74PRKCH0.78133639
75CSNK1G20.76964052
76RAF10.76090172
77CDK11A0.75982134
78MUSK0.75693785
79DYRK1B0.75631152
80SIK20.75564654
81MAP2K20.74822742
82DYRK1A0.74626808
83PRKCE0.73841738
84TAOK10.72599877
85MAP2K10.72360533
86PRKCI0.71724848
87CAMK2D0.69600592
88CAMK10.69551423
89RPS6KL10.69098978
90RPS6KC10.69098978
91MARK20.68968734
92RPS6KA20.67586215
93MTOR0.67280961
94OXSR10.66937777
95CAMK2G0.66201294
96IRAK20.64815477
97PRKD10.63754498
98ERBB30.62832967
99IRAK30.62153976
100CDC42BPA0.61918545
101MAPK120.61701234
102FGFR40.61467310
103MAP3K70.61340122
104WNK40.61054951
105DYRK20.60365977
106PIM20.60097988
107HIPK20.58946609
108BCR0.58220076
109EPHB10.57448042
110ERBB20.57267770
111DAPK30.57260129
112ILK0.57105331
113PDGFRA0.57078664
114EPHB20.56556840
115ICK0.56506189
116NEK60.56126939
117MAP3K130.54917019
118CAMK1G0.54677613
119WNK10.54278985
120RPS6KA60.54278563
121WNK30.53428250
122TESK20.52357546
123PRKCZ0.50677546
124ROCK20.50110002
125KDR0.49873562
126ADRBK10.48755739
127FGFR20.47696890
128BMX0.47204796
129TTN0.47096431
130MAPK100.46629540
131PTK20.46211034
132STK110.46133680
133FES0.45668297
134TNK20.45313580
135PINK10.45054761
136FGR0.44791337
137PDPK10.43644530
138ROCK10.42676067
139SGK20.41142920
140SIK30.40976956
141BMPR20.40427404
142STK390.40154462
143CSNK1G30.39763077
144SGK10.38407344

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047213.12257938
2Nicotine addiction_Homo sapiens_hsa050333.06491528
3Olfactory transduction_Homo sapiens_hsa047402.57100963
4Circadian entrainment_Homo sapiens_hsa047132.53599288
5GABAergic synapse_Homo sapiens_hsa047272.48801880
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.43754745
7Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.41297838
8Glutamatergic synapse_Homo sapiens_hsa047242.31322205
9Long-term potentiation_Homo sapiens_hsa047202.22924182
10Morphine addiction_Homo sapiens_hsa050322.21649980
11Insulin secretion_Homo sapiens_hsa049112.20604347
12Amphetamine addiction_Homo sapiens_hsa050312.11853276
13Dopaminergic synapse_Homo sapiens_hsa047282.10925898
14Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.05412215
15Taste transduction_Homo sapiens_hsa047421.91130365
16Cholinergic synapse_Homo sapiens_hsa047251.88674961
17Salivary secretion_Homo sapiens_hsa049701.87588626
18Serotonergic synapse_Homo sapiens_hsa047261.70072647
19Collecting duct acid secretion_Homo sapiens_hsa049661.69847607
20Gastric acid secretion_Homo sapiens_hsa049711.68874080
21Cyanoamino acid metabolism_Homo sapiens_hsa004601.68109648
22Cocaine addiction_Homo sapiens_hsa050301.63889664
23Aldosterone synthesis and secretion_Homo sapiens_hsa049251.62888811
24Notch signaling pathway_Homo sapiens_hsa043301.61167255
25Long-term depression_Homo sapiens_hsa047301.52365053
26Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.51302881
27Vibrio cholerae infection_Homo sapiens_hsa051101.49716598
28Renin secretion_Homo sapiens_hsa049241.45121650
29Oxytocin signaling pathway_Homo sapiens_hsa049211.40365441
30GnRH signaling pathway_Homo sapiens_hsa049121.39177697
31Gap junction_Homo sapiens_hsa045401.38229844
32Glycosaminoglycan degradation_Homo sapiens_hsa005311.35867604
33Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.33596868
34Calcium signaling pathway_Homo sapiens_hsa040201.30540076
35Axon guidance_Homo sapiens_hsa043601.28833490
36Sulfur relay system_Homo sapiens_hsa041221.25072813
37Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.19657552
38Estrogen signaling pathway_Homo sapiens_hsa049151.17230467
39Pancreatic secretion_Homo sapiens_hsa049721.12654846
40AMPK signaling pathway_Homo sapiens_hsa041521.11739625
41cAMP signaling pathway_Homo sapiens_hsa040241.11332368
42Melanogenesis_Homo sapiens_hsa049161.11277527
43Cardiac muscle contraction_Homo sapiens_hsa042601.10318891
44Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.07822259
45Glioma_Homo sapiens_hsa052141.02071297
46Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.01073849
47Type II diabetes mellitus_Homo sapiens_hsa049300.99961786
48Vitamin B6 metabolism_Homo sapiens_hsa007500.99127308
49Other glycan degradation_Homo sapiens_hsa005110.99044167
50Vascular smooth muscle contraction_Homo sapiens_hsa042700.98662718
51cGMP-PKG signaling pathway_Homo sapiens_hsa040220.97333582
52Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.97259527
53ErbB signaling pathway_Homo sapiens_hsa040120.94248936
54Thyroid hormone synthesis_Homo sapiens_hsa049180.87846863
55Phosphatidylinositol signaling system_Homo sapiens_hsa040700.86115088
56Phototransduction_Homo sapiens_hsa047440.80907530
57Alzheimers disease_Homo sapiens_hsa050100.80695659
58Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.79454713
59Fructose and mannose metabolism_Homo sapiens_hsa000510.79042183
60Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.77993073
61Phospholipase D signaling pathway_Homo sapiens_hsa040720.77867921
62Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.74032474
63Oxidative phosphorylation_Homo sapiens_hsa001900.73916385
64Dilated cardiomyopathy_Homo sapiens_hsa054140.72870442
65Inositol phosphate metabolism_Homo sapiens_hsa005620.70996714
66Arginine and proline metabolism_Homo sapiens_hsa003300.70727321
67Carbohydrate digestion and absorption_Homo sapiens_hsa049730.70260271
68Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.70180999
69Neurotrophin signaling pathway_Homo sapiens_hsa047220.69890994
70Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.69258871
71Ras signaling pathway_Homo sapiens_hsa040140.67525248
72Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.67136742
73Choline metabolism in cancer_Homo sapiens_hsa052310.65443488
74Glycerophospholipid metabolism_Homo sapiens_hsa005640.65400427
75Dorso-ventral axis formation_Homo sapiens_hsa043200.65257435
76VEGF signaling pathway_Homo sapiens_hsa043700.65191357
77Endometrial cancer_Homo sapiens_hsa052130.62793375
78Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.61052634
79Focal adhesion_Homo sapiens_hsa045100.59877123
80Prion diseases_Homo sapiens_hsa050200.59370627
81Oocyte meiosis_Homo sapiens_hsa041140.58848754
82Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.57335610
832-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.57199881
84MAPK signaling pathway_Homo sapiens_hsa040100.57120051
85Glucagon signaling pathway_Homo sapiens_hsa049220.56632269
86Parkinsons disease_Homo sapiens_hsa050120.56363662
87Rap1 signaling pathway_Homo sapiens_hsa040150.56341940
88Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.56238650
89Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.55893003
90Central carbon metabolism in cancer_Homo sapiens_hsa052300.55578374
91ECM-receptor interaction_Homo sapiens_hsa045120.54962369
92Alcoholism_Homo sapiens_hsa050340.54393334
93Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.53859783
94Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.53639449
95Insulin signaling pathway_Homo sapiens_hsa049100.52463971
96Fatty acid biosynthesis_Homo sapiens_hsa000610.52450810
97Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.51497534
98Renal cell carcinoma_Homo sapiens_hsa052110.50703595
99Histidine metabolism_Homo sapiens_hsa003400.50136523
100Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.50123732
101Sphingolipid signaling pathway_Homo sapiens_hsa040710.49979139
102Endocytosis_Homo sapiens_hsa041440.49589732
103SNARE interactions in vesicular transport_Homo sapiens_hsa041300.49221359
104Thyroid hormone signaling pathway_Homo sapiens_hsa049190.47407925
105Wnt signaling pathway_Homo sapiens_hsa043100.47221191
106Arginine biosynthesis_Homo sapiens_hsa002200.47209998
107Hippo signaling pathway_Homo sapiens_hsa043900.46546751
108Protein digestion and absorption_Homo sapiens_hsa049740.44768369
109Phenylalanine metabolism_Homo sapiens_hsa003600.43834292
110Adipocytokine signaling pathway_Homo sapiens_hsa049200.43536382
111Prolactin signaling pathway_Homo sapiens_hsa049170.42717747
112Circadian rhythm_Homo sapiens_hsa047100.41821981
113Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.40519620
114Tight junction_Homo sapiens_hsa045300.37822603
115Huntingtons disease_Homo sapiens_hsa050160.37655027
116Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.37561825
117Hedgehog signaling pathway_Homo sapiens_hsa043400.37434573
118Longevity regulating pathway - mammal_Homo sapiens_hsa042110.36664167
119Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.36285435
120Melanoma_Homo sapiens_hsa052180.34648751
121mTOR signaling pathway_Homo sapiens_hsa041500.34143730
122Regulation of autophagy_Homo sapiens_hsa041400.33914651
123Ovarian steroidogenesis_Homo sapiens_hsa049130.32140509
124Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.32139429
125Mineral absorption_Homo sapiens_hsa049780.32115476
126Bile secretion_Homo sapiens_hsa049760.31785423

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