

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | proteasome assembly (GO:0043248) | 6.65097956 |
| 2 | water-soluble vitamin biosynthetic process (GO:0042364) | 5.80310228 |
| 3 | rRNA modification (GO:0000154) | 5.48430072 |
| 4 | cullin deneddylation (GO:0010388) | 5.30429319 |
| 5 | rRNA methylation (GO:0031167) | 5.24774897 |
| 6 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 5.02261500 |
| 7 | regulation of immunoglobulin secretion (GO:0051023) | 4.97839439 |
| 8 | ribosome assembly (GO:0042255) | 4.91899809 |
| 9 | protein deneddylation (GO:0000338) | 4.74795586 |
| 10 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.69532460 |
| 11 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 4.57239607 |
| 12 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.45163552 |
| 13 | DNA deamination (GO:0045006) | 4.38880258 |
| 14 | DNA damage response, detection of DNA damage (GO:0042769) | 4.19612877 |
| 15 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.16201922 |
| 16 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.10765577 |
| 17 | DNA catabolic process, exonucleolytic (GO:0000738) | 4.05700420 |
| 18 | transcription from mitochondrial promoter (GO:0006390) | 3.93759077 |
| 19 | DNA double-strand break processing (GO:0000729) | 3.93711054 |
| 20 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.85270673 |
| 21 | pseudouridine synthesis (GO:0001522) | 3.83614319 |
| 22 | maturation of 5.8S rRNA (GO:0000460) | 3.81806312 |
| 23 | regulation of regulatory T cell differentiation (GO:0045589) | 3.80532169 |
| 24 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.78465470 |
| 25 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.78465470 |
| 26 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.78465470 |
| 27 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.76307331 |
| 28 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.76307331 |
| 29 | termination of RNA polymerase I transcription (GO:0006363) | 3.74606194 |
| 30 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.71400413 |
| 31 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.66789108 |
| 32 | negative regulation of ligase activity (GO:0051352) | 3.65800818 |
| 33 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.65800818 |
| 34 | chaperone-mediated protein transport (GO:0072321) | 3.60703929 |
| 35 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.57710081 |
| 36 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.57710081 |
| 37 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.57251362 |
| 38 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.51981458 |
| 39 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.51334466 |
| 40 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.51334466 |
| 41 | mitochondrial RNA metabolic process (GO:0000959) | 3.50319839 |
| 42 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.48675297 |
| 43 | formation of translation preinitiation complex (GO:0001731) | 3.40927964 |
| 44 | peptidyl-histidine modification (GO:0018202) | 3.40560568 |
| 45 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.40538058 |
| 46 | ribosome biogenesis (GO:0042254) | 3.40374191 |
| 47 | protein targeting to mitochondrion (GO:0006626) | 3.37203156 |
| 48 | positive regulation of DNA recombination (GO:0045911) | 3.36228413 |
| 49 | positive regulation of isotype switching (GO:0045830) | 3.35540880 |
| 50 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.34041215 |
| 51 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 3.30549528 |
| 52 | transcription initiation from RNA polymerase I promoter (GO:0006361) | 3.27074557 |
| 53 | negative regulation of B cell apoptotic process (GO:0002903) | 3.24784732 |
| 54 | tRNA processing (GO:0008033) | 3.23464859 |
| 55 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.23321501 |
| 56 | positive regulation of interleukin-17 production (GO:0032740) | 3.23149106 |
| 57 | respiratory chain complex IV assembly (GO:0008535) | 3.23015225 |
| 58 | protein localization to mitochondrion (GO:0070585) | 3.20440652 |
| 59 | IMP biosynthetic process (GO:0006188) | 3.20245481 |
| 60 | ATP synthesis coupled proton transport (GO:0015986) | 3.18745511 |
| 61 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.18745511 |
| 62 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.15467186 |
| 63 | positive regulation of ligase activity (GO:0051351) | 3.14354150 |
| 64 | rRNA processing (GO:0006364) | 3.12496721 |
| 65 | establishment of protein localization to mitochondrion (GO:0072655) | 3.11439755 |
| 66 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.11221036 |
| 67 | termination of RNA polymerase III transcription (GO:0006386) | 3.11221036 |
| 68 | transcription from RNA polymerase I promoter (GO:0006360) | 3.10971658 |
| 69 | tRNA metabolic process (GO:0006399) | 3.08665329 |
| 70 | protein complex biogenesis (GO:0070271) | 3.08081032 |
| 71 | rRNA metabolic process (GO:0016072) | 3.06143810 |
| 72 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.05989188 |
| 73 | tRNA aminoacylation (GO:0043039) | 3.00489226 |
| 74 | amino acid activation (GO:0043038) | 3.00489226 |
| 75 | regulation of chronic inflammatory response (GO:0002676) | 3.00020961 |
| 76 | tRNA aminoacylation for protein translation (GO:0006418) | 2.99994674 |
| 77 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.99782300 |
| 78 | tRNA methylation (GO:0030488) | 2.95505925 |
| 79 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.94687278 |
| 80 | NADH dehydrogenase complex assembly (GO:0010257) | 2.94687278 |
| 81 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.94687278 |
| 82 | protein neddylation (GO:0045116) | 2.92242752 |
| 83 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.90805739 |
| 84 | IMP metabolic process (GO:0046040) | 2.90614339 |
| 85 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.90308607 |
| 86 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class | 2.89720310 |
| 87 | positive regulation of cell cycle arrest (GO:0071158) | 2.88694077 |
| 88 | regulation of cellular amine metabolic process (GO:0033238) | 2.87151892 |
| 89 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.84445345 |
| 90 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.82992347 |
| 91 | ncRNA metabolic process (GO:0034660) | 2.82858673 |
| 92 | synapsis (GO:0007129) | 2.82757209 |
| 93 | negative regulation of protein ubiquitination (GO:0031397) | 2.79448216 |
| 94 | ncRNA processing (GO:0034470) | 2.78303323 |
| 95 | regulation of ligase activity (GO:0051340) | 2.77250448 |
| 96 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.76975018 |
| 97 | tRNA modification (GO:0006400) | 2.69435180 |
| 98 | nucleobase biosynthetic process (GO:0046112) | 2.67890955 |
| 99 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.66466824 |
| 100 | protein K6-linked ubiquitination (GO:0085020) | 2.64734202 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.44886689 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.77761814 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.70448326 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.04001669 |
| 5 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.04075814 |
| 6 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.99806657 |
| 7 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.84811491 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.75577287 |
| 9 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.66139913 |
| 10 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.61509756 |
| 11 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.60412546 |
| 12 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.59571547 |
| 13 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.56006045 |
| 14 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.48807503 |
| 15 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.44399560 |
| 16 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.37353184 |
| 17 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.29036174 |
| 18 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.23698321 |
| 19 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.12420263 |
| 20 | VDR_22108803_ChIP-Seq_LS180_Human | 2.08139174 |
| 21 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 2.06112279 |
| 22 | EWS_26573619_Chip-Seq_HEK293_Human | 2.05541240 |
| 23 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.02153174 |
| 24 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.91682636 |
| 25 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.84991275 |
| 26 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.83744151 |
| 27 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.82216050 |
| 28 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.80313148 |
| 29 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.79462647 |
| 30 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.72385670 |
| 31 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.69985618 |
| 32 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.59088273 |
| 33 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.55717088 |
| 34 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.54156388 |
| 35 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.50552204 |
| 36 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.50229665 |
| 37 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.48995713 |
| 38 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.44295003 |
| 39 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.42538882 |
| 40 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.41534827 |
| 41 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.41011702 |
| 42 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.41008563 |
| 43 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.40768904 |
| 44 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.38753304 |
| 45 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.38666717 |
| 46 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.37079318 |
| 47 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.37072852 |
| 48 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.36935744 |
| 49 | FUS_26573619_Chip-Seq_HEK293_Human | 1.34548591 |
| 50 | P300_19829295_ChIP-Seq_ESCs_Human | 1.30862476 |
| 51 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.29524820 |
| 52 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.28003265 |
| 53 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.27333275 |
| 54 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.27190426 |
| 55 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.27190426 |
| 56 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.25195591 |
| 57 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.19913026 |
| 58 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.18736891 |
| 59 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.18611252 |
| 60 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.16929431 |
| 61 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.14791961 |
| 62 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.12588282 |
| 63 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.10646163 |
| 64 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.09381008 |
| 65 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.08461850 |
| 66 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.07540130 |
| 67 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.06202206 |
| 68 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.05106690 |
| 69 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.04840969 |
| 70 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.04773343 |
| 71 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.04416674 |
| 72 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.04416674 |
| 73 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.04029848 |
| 74 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.03816951 |
| 75 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.03264881 |
| 76 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.01753167 |
| 77 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.00662258 |
| 78 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.00418251 |
| 79 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.97171592 |
| 80 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 0.96295674 |
| 81 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.96089388 |
| 82 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 0.94993330 |
| 83 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.94734788 |
| 84 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.93813664 |
| 85 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.93439206 |
| 86 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.92671732 |
| 87 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.91583602 |
| 88 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.90957885 |
| 89 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.90586058 |
| 90 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.90462559 |
| 91 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.89715313 |
| 92 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.89681405 |
| 93 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.88201148 |
| 94 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.87514238 |
| 95 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.87219714 |
| 96 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.86352950 |
| 97 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.86343706 |
| 98 | NCOR_22424771_ChIP-Seq_293T_Human | 0.86313798 |
| 99 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.86140120 |
| 100 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.85933600 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0004147_increased_porphyrin_level | 3.14548765 |
| 2 | MP0003718_maternal_effect | 3.11123297 |
| 3 | MP0008058_abnormal_DNA_repair | 3.10129945 |
| 4 | MP0003195_calcinosis | 2.91294117 |
| 5 | MP0010386_abnormal_urinary_bladder | 2.87044762 |
| 6 | MP0002138_abnormal_hepatobiliary_system | 2.86176804 |
| 7 | MP0002102_abnormal_ear_morphology | 2.68887767 |
| 8 | MP0004957_abnormal_blastocyst_morpholog | 2.63254583 |
| 9 | MP0003786_premature_aging | 2.48726820 |
| 10 | MP0003950_abnormal_plasma_membrane | 2.46459054 |
| 11 | MP0001835_abnormal_antigen_presentation | 2.29797599 |
| 12 | MP0003806_abnormal_nucleotide_metabolis | 2.26389373 |
| 13 | MP0008877_abnormal_DNA_methylation | 2.16047336 |
| 14 | MP0003300_gastrointestinal_ulcer | 2.15134183 |
| 15 | MP0003693_abnormal_embryo_hatching | 2.12582641 |
| 16 | MP0000465_gastrointestinal_hemorrhage | 2.11906506 |
| 17 | MP0006036_abnormal_mitochondrial_physio | 2.11555833 |
| 18 | MP0001853_heart_inflammation | 2.06455639 |
| 19 | MP0008872_abnormal_physiological_respon | 1.95235764 |
| 20 | MP0005084_abnormal_gallbladder_morpholo | 1.94588538 |
| 21 | MP0010094_abnormal_chromosome_stability | 1.91445590 |
| 22 | MP0006035_abnormal_mitochondrial_morpho | 1.88224951 |
| 23 | MP0008875_abnormal_xenobiotic_pharmacok | 1.85102970 |
| 24 | MP0001968_abnormal_touch/_nociception | 1.84992106 |
| 25 | MP0002163_abnormal_gland_morphology | 1.77977957 |
| 26 | MP0002277_abnormal_respiratory_mucosa | 1.76247197 |
| 27 | MP0008057_abnormal_DNA_replication | 1.72105776 |
| 28 | MP0005379_endocrine/exocrine_gland_phen | 1.69792723 |
| 29 | MP0004782_abnormal_surfactant_physiolog | 1.68914824 |
| 30 | MP0009697_abnormal_copulation | 1.68903156 |
| 31 | MP0001873_stomach_inflammation | 1.66963109 |
| 32 | MP0009333_abnormal_splenocyte_physiolog | 1.65311192 |
| 33 | MP0004145_abnormal_muscle_electrophysio | 1.63880141 |
| 34 | MP0002736_abnormal_nociception_after | 1.63050371 |
| 35 | MP0001984_abnormal_olfaction | 1.61371349 |
| 36 | MP0006292_abnormal_olfactory_placode | 1.55942460 |
| 37 | MP0005310_abnormal_salivary_gland | 1.55026762 |
| 38 | MP0003567_abnormal_fetal_cardiomyocyte | 1.45394486 |
| 39 | MP0004885_abnormal_endolymph | 1.43909278 |
| 40 | MP0005085_abnormal_gallbladder_physiolo | 1.39703842 |
| 41 | MP0001293_anophthalmia | 1.36866380 |
| 42 | MP0002006_tumorigenesis | 1.34362011 |
| 43 | MP0005645_abnormal_hypothalamus_physiol | 1.33533861 |
| 44 | MP0003186_abnormal_redox_activity | 1.25174895 |
| 45 | MP0001485_abnormal_pinna_reflex | 1.21333083 |
| 46 | MP0005671_abnormal_response_to | 1.20379701 |
| 47 | MP0002148_abnormal_hypersensitivity_rea | 1.19941142 |
| 48 | MP0002166_altered_tumor_susceptibility | 1.18275338 |
| 49 | MP0006072_abnormal_retinal_apoptosis | 1.17415873 |
| 50 | MP0005387_immune_system_phenotype | 1.16043670 |
| 51 | MP0001790_abnormal_immune_system | 1.16043670 |
| 52 | MP0002837_dystrophic_cardiac_calcinosis | 1.13047615 |
| 53 | MP0008789_abnormal_olfactory_epithelium | 1.08946735 |
| 54 | MP0000383_abnormal_hair_follicle | 1.08524623 |
| 55 | MP0003111_abnormal_nucleus_morphology | 1.06621673 |
| 56 | MP0001501_abnormal_sleep_pattern | 1.05993429 |
| 57 | MP0003011_delayed_dark_adaptation | 1.04120084 |
| 58 | MP0001529_abnormal_vocalization | 1.03160844 |
| 59 | MP0005551_abnormal_eye_electrophysiolog | 1.01872916 |
| 60 | MP0005395_other_phenotype | 1.00283960 |
| 61 | MP0002396_abnormal_hematopoietic_system | 0.98542529 |
| 62 | MP0004215_abnormal_myocardial_fiber | 0.98136712 |
| 63 | MP0005389_reproductive_system_phenotype | 0.96954278 |
| 64 | MP0002160_abnormal_reproductive_system | 0.95667282 |
| 65 | MP0001661_extended_life_span | 0.95451384 |
| 66 | MP0003119_abnormal_digestive_system | 0.94841599 |
| 67 | MP0002693_abnormal_pancreas_physiology | 0.92013168 |
| 68 | MP0000538_abnormal_urinary_bladder | 0.91715834 |
| 69 | MP0001764_abnormal_homeostasis | 0.89775738 |
| 70 | MP0003763_abnormal_thymus_physiology | 0.89437050 |
| 71 | MP0003077_abnormal_cell_cycle | 0.89059772 |
| 72 | MP0003646_muscle_fatigue | 0.89008465 |
| 73 | MP0001881_abnormal_mammary_gland | 0.85893296 |
| 74 | MP0001800_abnormal_humoral_immune | 0.84673054 |
| 75 | MP0000647_abnormal_sebaceous_gland | 0.84416428 |
| 76 | MP0002876_abnormal_thyroid_physiology | 0.84144324 |
| 77 | MP0005646_abnormal_pituitary_gland | 0.83284583 |
| 78 | MP0003283_abnormal_digestive_organ | 0.82346419 |
| 79 | MP0000685_abnormal_immune_system | 0.80321867 |
| 80 | MP0003866_abnormal_defecation | 0.80042963 |
| 81 | MP0005410_abnormal_fertilization | 0.79874795 |
| 82 | MP0002210_abnormal_sex_determination | 0.78732529 |
| 83 | MP0001929_abnormal_gametogenesis | 0.78225265 |
| 84 | MP0008873_increased_physiological_sensi | 0.77166133 |
| 85 | MP0001919_abnormal_reproductive_system | 0.74834989 |
| 86 | MP0002272_abnormal_nervous_system | 0.74459407 |
| 87 | MP0003936_abnormal_reproductive_system | 0.71749607 |
| 88 | MP0008932_abnormal_embryonic_tissue | 0.70320715 |
| 89 | MP0003137_abnormal_impulse_conducting | 0.69051151 |
| 90 | MP0001119_abnormal_female_reproductive | 0.68186521 |
| 91 | MP0002405_respiratory_system_inflammati | 0.67778381 |
| 92 | MP0008007_abnormal_cellular_replicative | 0.66187127 |
| 93 | MP0000372_irregular_coat_pigmentation | 0.65096880 |
| 94 | MP0004142_abnormal_muscle_tone | 0.63810904 |
| 95 | MP0005332_abnormal_amino_acid | 0.62957598 |
| 96 | MP0009764_decreased_sensitivity_to | 0.62734853 |
| 97 | MP0001348_abnormal_lacrimal_gland | 0.61862902 |
| 98 | MP0000689_abnormal_spleen_morphology | 0.61664952 |
| 99 | MP0000653_abnormal_sex_gland | 0.60780777 |
| 100 | MP0002398_abnormal_bone_marrow | 0.60345620 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Increased hepatocellular lipid droplets (HP:0006565) | 4.06969871 |
| 2 | Abnormality of the pons (HP:0007361) | 3.97492139 |
| 3 | Lipid accumulation in hepatocytes (HP:0006561) | 3.75245709 |
| 4 | Large for gestational age (HP:0001520) | 3.53629899 |
| 5 | 3-Methylglutaconic aciduria (HP:0003535) | 3.34247949 |
| 6 | Increased CSF lactate (HP:0002490) | 3.30086672 |
| 7 | Congenital, generalized hypertrichosis (HP:0004540) | 3.29163475 |
| 8 | Mitochondrial inheritance (HP:0001427) | 3.24336547 |
| 9 | Acute necrotizing encephalopathy (HP:0006965) | 3.22069687 |
| 10 | Volvulus (HP:0002580) | 3.05047760 |
| 11 | Acute encephalopathy (HP:0006846) | 3.04805401 |
| 12 | Increased serum lactate (HP:0002151) | 3.01713026 |
| 13 | Duplicated collecting system (HP:0000081) | 3.01112867 |
| 14 | Methylmalonic acidemia (HP:0002912) | 3.00850599 |
| 15 | Urethral obstruction (HP:0000796) | 2.98132984 |
| 16 | Pancytopenia (HP:0001876) | 2.94598926 |
| 17 | Hypoplasia of the pons (HP:0012110) | 2.87213289 |
| 18 | Renal Fanconi syndrome (HP:0001994) | 2.85601320 |
| 19 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.85378479 |
| 20 | Hyperglycinemia (HP:0002154) | 2.84923290 |
| 21 | Stomatitis (HP:0010280) | 2.83700130 |
| 22 | Abnormality of the renal collecting system (HP:0004742) | 2.74223199 |
| 23 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.71753310 |
| 24 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.71388123 |
| 25 | Progressive macrocephaly (HP:0004481) | 2.70858960 |
| 26 | Abnormality of serum amino acid levels (HP:0003112) | 2.70558544 |
| 27 | Hepatic necrosis (HP:0002605) | 2.68654410 |
| 28 | Exertional dyspnea (HP:0002875) | 2.65340977 |
| 29 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.63396836 |
| 30 | Hepatocellular necrosis (HP:0001404) | 2.53462965 |
| 31 | IgG deficiency (HP:0004315) | 2.51014292 |
| 32 | Type I transferrin isoform profile (HP:0003642) | 2.50996881 |
| 33 | Increased intramyocellular lipid droplets (HP:0012240) | 2.50647548 |
| 34 | Abnormality of methionine metabolism (HP:0010901) | 2.43101253 |
| 35 | Oral leukoplakia (HP:0002745) | 2.42608384 |
| 36 | Pancreatic cysts (HP:0001737) | 2.41776679 |
| 37 | Submucous cleft hard palate (HP:0000176) | 2.41102416 |
| 38 | Hypothermia (HP:0002045) | 2.40906539 |
| 39 | Cerebral edema (HP:0002181) | 2.38655606 |
| 40 | Methylmalonic aciduria (HP:0012120) | 2.38086294 |
| 41 | Megaloblastic anemia (HP:0001889) | 2.37544681 |
| 42 | Abnormality of the ileum (HP:0001549) | 2.36294396 |
| 43 | Testicular atrophy (HP:0000029) | 2.34555174 |
| 44 | Abnormal lung lobation (HP:0002101) | 2.32838562 |
| 45 | Lactic acidosis (HP:0003128) | 2.24424536 |
| 46 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.24054247 |
| 47 | Hypoglycemic coma (HP:0001325) | 2.23555829 |
| 48 | Respiratory difficulties (HP:0002880) | 2.21222400 |
| 49 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.20438601 |
| 50 | Increased serum pyruvate (HP:0003542) | 2.20113708 |
| 51 | Degeneration of anterior horn cells (HP:0002398) | 2.15368903 |
| 52 | Abnormality of the anterior horn cell (HP:0006802) | 2.15368903 |
| 53 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.14095823 |
| 54 | Lethargy (HP:0001254) | 2.12143183 |
| 55 | Meckel diverticulum (HP:0002245) | 2.11811873 |
| 56 | Colon cancer (HP:0003003) | 2.11766921 |
| 57 | Abnormality of the labia minora (HP:0012880) | 2.11421907 |
| 58 | Ureteral duplication (HP:0000073) | 2.11311972 |
| 59 | Abnormality of the preputium (HP:0100587) | 2.09302451 |
| 60 | Reduced antithrombin III activity (HP:0001976) | 2.05412534 |
| 61 | Nephronophthisis (HP:0000090) | 2.05097170 |
| 62 | Cerebral hemorrhage (HP:0001342) | 2.04577009 |
| 63 | Conjunctival hamartoma (HP:0100780) | 2.03879278 |
| 64 | Increased muscle lipid content (HP:0009058) | 2.03710436 |
| 65 | Abnormality of glycine metabolism (HP:0010895) | 2.02879142 |
| 66 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.02879142 |
| 67 | Abnormality of vitamin B metabolism (HP:0004340) | 2.02833086 |
| 68 | Abnormality of midbrain morphology (HP:0002418) | 2.02805016 |
| 69 | Molar tooth sign on MRI (HP:0002419) | 2.02805016 |
| 70 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.02557223 |
| 71 | Exercise intolerance (HP:0003546) | 2.01449154 |
| 72 | Optic disc pallor (HP:0000543) | 2.01401612 |
| 73 | Abnormality of urine glucose concentration (HP:0011016) | 1.99716741 |
| 74 | Glycosuria (HP:0003076) | 1.99716741 |
| 75 | Generalized aminoaciduria (HP:0002909) | 1.97970825 |
| 76 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.97102050 |
| 77 | Supernumerary spleens (HP:0009799) | 1.96188071 |
| 78 | Limb hypertonia (HP:0002509) | 1.96071260 |
| 79 | Pendular nystagmus (HP:0012043) | 1.95401712 |
| 80 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.94959920 |
| 81 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.94959920 |
| 82 | Abnormality of alanine metabolism (HP:0010916) | 1.94014304 |
| 83 | Hyperalaninemia (HP:0003348) | 1.94014304 |
| 84 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.94014304 |
| 85 | Type 2 muscle fiber atrophy (HP:0003554) | 1.92933826 |
| 86 | Horseshoe kidney (HP:0000085) | 1.92792665 |
| 87 | Hypomagnesemia (HP:0002917) | 1.91818428 |
| 88 | Abnormality of glycolysis (HP:0004366) | 1.89103640 |
| 89 | Hypoproteinemia (HP:0003075) | 1.87378538 |
| 90 | Respiratory failure (HP:0002878) | 1.81252309 |
| 91 | Clubbing of toes (HP:0100760) | 1.79871671 |
| 92 | Aplastic anemia (HP:0001915) | 1.74392628 |
| 93 | Sparse eyelashes (HP:0000653) | 1.73972267 |
| 94 | Fatigue (HP:0012378) | 1.73835525 |
| 95 | Breast carcinoma (HP:0003002) | 1.73594108 |
| 96 | Constricted visual fields (HP:0001133) | 1.72887752 |
| 97 | Myelodysplasia (HP:0002863) | 1.72481181 |
| 98 | Spinal muscular atrophy (HP:0007269) | 1.72263330 |
| 99 | Neoplasm of the adrenal gland (HP:0100631) | 1.71960884 |
| 100 | Abnormality of renal resorption (HP:0011038) | 1.70661192 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TSSK6 | 5.78325063 |
| 2 | EIF2AK3 | 4.41023399 |
| 3 | EIF2AK1 | 4.11305760 |
| 4 | MST4 | 3.81128216 |
| 5 | BUB1 | 3.53856201 |
| 6 | VRK2 | 3.15152178 |
| 7 | TAF1 | 2.91331576 |
| 8 | PBK | 2.77501222 |
| 9 | ADRBK2 | 2.69728134 |
| 10 | NEK1 | 2.50953815 |
| 11 | MKNK2 | 2.33908106 |
| 12 | SRPK1 | 2.29459507 |
| 13 | NUAK1 | 2.28948481 |
| 14 | PLK3 | 2.01639524 |
| 15 | ZAK | 1.99285230 |
| 16 | VRK1 | 1.86701458 |
| 17 | MKNK1 | 1.81624009 |
| 18 | TLK1 | 1.75730875 |
| 19 | STK39 | 1.67367556 |
| 20 | PASK | 1.53284659 |
| 21 | EIF2AK2 | 1.50388526 |
| 22 | MAP3K12 | 1.41336500 |
| 23 | FRK | 1.37618345 |
| 24 | STK16 | 1.34611062 |
| 25 | ALK | 1.33815276 |
| 26 | NME1 | 1.33546202 |
| 27 | GRK1 | 1.32483853 |
| 28 | TXK | 1.27319003 |
| 29 | OXSR1 | 1.18112909 |
| 30 | BMPR1B | 1.16758738 |
| 31 | TEC | 1.11398825 |
| 32 | TRIM28 | 1.10027052 |
| 33 | TAOK3 | 1.08168511 |
| 34 | WNK4 | 0.95659464 |
| 35 | CDC7 | 0.94942285 |
| 36 | INSRR | 0.94481003 |
| 37 | BCR | 0.94139179 |
| 38 | ACVR1B | 0.90984315 |
| 39 | PLK2 | 0.86643799 |
| 40 | STK24 | 0.84473531 |
| 41 | TGFBR1 | 0.83129153 |
| 42 | PAK4 | 0.81629421 |
| 43 | CDK8 | 0.76190108 |
| 44 | PLK4 | 0.75310001 |
| 45 | CLK1 | 0.74909406 |
| 46 | ITK | 0.73764679 |
| 47 | STK4 | 0.69404353 |
| 48 | PLK1 | 0.69366587 |
| 49 | DYRK2 | 0.68542396 |
| 50 | PINK1 | 0.67215284 |
| 51 | PDK2 | 0.66910925 |
| 52 | MAP3K14 | 0.66312765 |
| 53 | WNK3 | 0.65769937 |
| 54 | GRK5 | 0.65137753 |
| 55 | TIE1 | 0.62292198 |
| 56 | FGFR1 | 0.61525986 |
| 57 | CCNB1 | 0.59216479 |
| 58 | MAP4K2 | 0.57278429 |
| 59 | TNIK | 0.57261474 |
| 60 | PRKCE | 0.55429949 |
| 61 | STK3 | 0.54528764 |
| 62 | IKBKB | 0.53071259 |
| 63 | PRKCG | 0.51702606 |
| 64 | CSNK1G2 | 0.49876579 |
| 65 | MYLK | 0.48436124 |
| 66 | ADRBK1 | 0.48290544 |
| 67 | STK38L | 0.47970586 |
| 68 | MAP2K6 | 0.45377476 |
| 69 | CSNK1A1L | 0.44734350 |
| 70 | RPS6KA5 | 0.40614996 |
| 71 | ATR | 0.40322311 |
| 72 | AURKB | 0.40314955 |
| 73 | DAPK1 | 0.40150155 |
| 74 | CSNK1E | 0.39862409 |
| 75 | PIK3CG | 0.39838331 |
| 76 | CSNK1G1 | 0.39310788 |
| 77 | PRKCQ | 0.38708826 |
| 78 | BCKDK | 0.38433276 |
| 79 | CSNK2A2 | 0.37949434 |
| 80 | PHKG2 | 0.37590253 |
| 81 | PHKG1 | 0.37590253 |
| 82 | AKT3 | 0.36766153 |
| 83 | KIT | 0.36715422 |
| 84 | CSNK1G3 | 0.35602065 |
| 85 | MAPKAPK5 | 0.35235456 |
| 86 | ATM | 0.34815163 |
| 87 | CSNK2A1 | 0.33675898 |
| 88 | IRAK1 | 0.33383533 |
| 89 | TTK | 0.30909376 |
| 90 | ILK | 0.29804156 |
| 91 | WEE1 | 0.29558812 |
| 92 | NLK | 0.29435515 |
| 93 | JAK3 | 0.26927660 |
| 94 | SIK3 | 0.25243969 |
| 95 | CAMK2A | 0.22866529 |
| 96 | IKBKE | 0.20022181 |
| 97 | ERBB3 | 0.19955252 |
| 98 | CHEK1 | 0.17704426 |
| 99 | LCK | 0.16438884 |
| 100 | PRKCA | 0.16122344 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.21268908 |
| 2 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.97239596 |
| 3 | Protein export_Homo sapiens_hsa03060 | 3.44110538 |
| 4 | Basal transcription factors_Homo sapiens_hsa03022 | 3.06843226 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 2.55434425 |
| 6 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.53702869 |
| 7 | Asthma_Homo sapiens_hsa05310 | 2.29815674 |
| 8 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.29114668 |
| 9 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.25954610 |
| 10 | RNA transport_Homo sapiens_hsa03013 | 2.15672683 |
| 11 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.14983201 |
| 12 | Parkinsons disease_Homo sapiens_hsa05012 | 2.03273218 |
| 13 | Allograft rejection_Homo sapiens_hsa05330 | 1.93463549 |
| 14 | RNA degradation_Homo sapiens_hsa03018 | 1.89176949 |
| 15 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.83733339 |
| 16 | Mismatch repair_Homo sapiens_hsa03430 | 1.71929148 |
| 17 | Spliceosome_Homo sapiens_hsa03040 | 1.71313764 |
| 18 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.69580456 |
| 19 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.68799823 |
| 20 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.67167578 |
| 21 | Homologous recombination_Homo sapiens_hsa03440 | 1.62020991 |
| 22 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.60599143 |
| 23 | Ribosome_Homo sapiens_hsa03010 | 1.60560333 |
| 24 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.47049848 |
| 25 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.46216043 |
| 26 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.45753258 |
| 27 | DNA replication_Homo sapiens_hsa03030 | 1.36754515 |
| 28 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.35404260 |
| 29 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.31296770 |
| 30 | Huntingtons disease_Homo sapiens_hsa05016 | 1.25122058 |
| 31 | Phototransduction_Homo sapiens_hsa04744 | 1.16925515 |
| 32 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.15838592 |
| 33 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.13931422 |
| 34 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.12083082 |
| 35 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.11947263 |
| 36 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.10028343 |
| 37 | Purine metabolism_Homo sapiens_hsa00230 | 1.09787409 |
| 38 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.09470984 |
| 39 | Alzheimers disease_Homo sapiens_hsa05010 | 1.07725280 |
| 40 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.05369109 |
| 41 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.03880975 |
| 42 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.03384391 |
| 43 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.01856290 |
| 44 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.97187148 |
| 45 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.93761114 |
| 46 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.93585051 |
| 47 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.91650064 |
| 48 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.83698523 |
| 49 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.83453516 |
| 50 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.81861270 |
| 51 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.81453979 |
| 52 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.80825810 |
| 53 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.78275063 |
| 54 | Base excision repair_Homo sapiens_hsa03410 | 0.76488839 |
| 55 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.75345518 |
| 56 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.73932331 |
| 57 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.72377769 |
| 58 | Peroxisome_Homo sapiens_hsa04146 | 0.71267467 |
| 59 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.69601921 |
| 60 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.67615030 |
| 61 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.66239167 |
| 62 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.66198475 |
| 63 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.65394173 |
| 64 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.63812137 |
| 65 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.62101625 |
| 66 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.61651023 |
| 67 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.61565819 |
| 68 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.61471101 |
| 69 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.59979958 |
| 70 | Measles_Homo sapiens_hsa05162 | 0.59945858 |
| 71 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.59714171 |
| 72 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.59663162 |
| 73 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.58988088 |
| 74 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.56606127 |
| 75 | Metabolic pathways_Homo sapiens_hsa01100 | 0.56498637 |
| 76 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.56051074 |
| 77 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.54816556 |
| 78 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.52599020 |
| 79 | Nicotine addiction_Homo sapiens_hsa05033 | 0.50329555 |
| 80 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.49773951 |
| 81 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.49236653 |
| 82 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.45405842 |
| 83 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.43204639 |
| 84 | Mineral absorption_Homo sapiens_hsa04978 | 0.42717498 |
| 85 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.42666034 |
| 86 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.42174130 |
| 87 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.42058163 |
| 88 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.40305785 |
| 89 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.40231055 |
| 90 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.39680833 |
| 91 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.38039767 |
| 92 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.37613314 |
| 93 | Retinol metabolism_Homo sapiens_hsa00830 | 0.37277894 |
| 94 | Legionellosis_Homo sapiens_hsa05134 | 0.36847685 |
| 95 | Carbon metabolism_Homo sapiens_hsa01200 | 0.36803976 |
| 96 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.36768300 |
| 97 | Olfactory transduction_Homo sapiens_hsa04740 | 0.35528364 |
| 98 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.33924907 |
| 99 | Cell cycle_Homo sapiens_hsa04110 | 0.32076749 |
| 100 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.31150805 |

