

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosome assembly (GO:0042255) | 5.19333972 |
| 2 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 4.83500556 |
| 3 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 4.68501669 |
| 4 | DNA double-strand break processing (GO:0000729) | 4.66252447 |
| 5 | urate metabolic process (GO:0046415) | 4.62909687 |
| 6 | rRNA modification (GO:0000154) | 4.34294458 |
| 7 | DNA deamination (GO:0045006) | 4.30568780 |
| 8 | ribosomal large subunit biogenesis (GO:0042273) | 4.16683001 |
| 9 | segment specification (GO:0007379) | 4.07909766 |
| 10 | ncRNA catabolic process (GO:0034661) | 4.03431541 |
| 11 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.01038522 |
| 12 | positive regulation of protein homodimerization activity (GO:0090073) | 3.99062405 |
| 13 | proteasome assembly (GO:0043248) | 3.85910272 |
| 14 | chaperone-mediated protein transport (GO:0072321) | 3.76462232 |
| 15 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.74047617 |
| 16 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.70883594 |
| 17 | isotype switching (GO:0045190) | 3.70883594 |
| 18 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.70883594 |
| 19 | rRNA methylation (GO:0031167) | 3.66823520 |
| 20 | ribosomal small subunit assembly (GO:0000028) | 3.59479891 |
| 21 | ATP synthesis coupled proton transport (GO:0015986) | 3.56345037 |
| 22 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.56345037 |
| 23 | intracellular protein transmembrane import (GO:0044743) | 3.53611293 |
| 24 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.49500955 |
| 25 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.48164779 |
| 26 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.48119642 |
| 27 | spliceosomal snRNP assembly (GO:0000387) | 3.46867371 |
| 28 | labyrinthine layer development (GO:0060711) | 3.43692411 |
| 29 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.42457202 |
| 30 | regulation of sarcomere organization (GO:0060297) | 3.40911951 |
| 31 | regulation of immunoglobulin secretion (GO:0051023) | 3.39070137 |
| 32 | positive regulation of ligase activity (GO:0051351) | 3.38854228 |
| 33 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.36074691 |
| 34 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.31727499 |
| 35 | negative regulation of ligase activity (GO:0051352) | 3.27917397 |
| 36 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.27917397 |
| 37 | ubiquinone biosynthetic process (GO:0006744) | 3.26601506 |
| 38 | rRNA processing (GO:0006364) | 3.24799529 |
| 39 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.19190419 |
| 40 | regulation of T cell chemotaxis (GO:0010819) | 3.18461599 |
| 41 | positive regulation of T cell chemotaxis (GO:0010820) | 3.18461599 |
| 42 | purine nucleotide salvage (GO:0032261) | 3.18029975 |
| 43 | rRNA metabolic process (GO:0016072) | 3.16492674 |
| 44 | chromatin remodeling at centromere (GO:0031055) | 3.16370926 |
| 45 | positive regulation of translational initiation (GO:0045948) | 3.15449863 |
| 46 | ubiquinone metabolic process (GO:0006743) | 3.14749782 |
| 47 | maturation of 5.8S rRNA (GO:0000460) | 3.14014418 |
| 48 | DNA integration (GO:0015074) | 3.12992553 |
| 49 | response to nitric oxide (GO:0071731) | 3.09460782 |
| 50 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.08766835 |
| 51 | CENP-A containing nucleosome assembly (GO:0034080) | 3.08384138 |
| 52 | protein complex biogenesis (GO:0070271) | 3.07711733 |
| 53 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.05371199 |
| 54 | IMP biosynthetic process (GO:0006188) | 3.04267721 |
| 55 | termination of RNA polymerase I transcription (GO:0006363) | 3.03487036 |
| 56 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.02180260 |
| 57 | 7-methylguanosine mRNA capping (GO:0006370) | 2.96865264 |
| 58 | AMP metabolic process (GO:0046033) | 2.96581931 |
| 59 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.95716883 |
| 60 | pseudouridine synthesis (GO:0001522) | 2.94939097 |
| 61 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.94929498 |
| 62 | NADH dehydrogenase complex assembly (GO:0010257) | 2.94929498 |
| 63 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.94929498 |
| 64 | purine nucleobase metabolic process (GO:0006144) | 2.93768862 |
| 65 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.90545710 |
| 66 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.90388167 |
| 67 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.90388167 |
| 68 | 7-methylguanosine RNA capping (GO:0009452) | 2.90293809 |
| 69 | RNA capping (GO:0036260) | 2.90293809 |
| 70 | membrane repolarization during cardiac muscle cell action potential (GO:0086013) | 2.89102263 |
| 71 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.88941969 |
| 72 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.88523522 |
| 73 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.88493950 |
| 74 | somatic recombination of immunoglobulin gene segments (GO:0016447) | 2.87270989 |
| 75 | purine nucleobase biosynthetic process (GO:0009113) | 2.87073228 |
| 76 | cellular component biogenesis (GO:0044085) | 2.86631756 |
| 77 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.86475062 |
| 78 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.86475062 |
| 79 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.86475062 |
| 80 | regulation of ligase activity (GO:0051340) | 2.83827349 |
| 81 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.83798686 |
| 82 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.83798686 |
| 83 | ribosome biogenesis (GO:0042254) | 2.82163481 |
| 84 | resolution of meiotic recombination intermediates (GO:0000712) | 2.80603808 |
| 85 | nucleobase biosynthetic process (GO:0046112) | 2.80051036 |
| 86 | positive regulation of interleukin-17 production (GO:0032740) | 2.79628172 |
| 87 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:0000288) | 2.74424646 |
| 88 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.72562065 |
| 89 | IMP metabolic process (GO:0046040) | 2.70973699 |
| 90 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.70665258 |
| 91 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.70665258 |
| 92 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.68334721 |
| 93 | quinone biosynthetic process (GO:1901663) | 2.67590109 |
| 94 | respiratory chain complex IV assembly (GO:0008535) | 2.67400762 |
| 95 | membrane repolarization during action potential (GO:0086011) | 2.67290052 |
| 96 | somatic diversification of immunoglobulins (GO:0016445) | 2.66582978 |
| 97 | acrosome assembly (GO:0001675) | 2.65516757 |
| 98 | histone exchange (GO:0043486) | 2.63244427 |
| 99 | intracellular protein transmembrane transport (GO:0065002) | 2.62197087 |
| 100 | indolalkylamine catabolic process (GO:0046218) | 2.60933328 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.61435190 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.19734210 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.80421846 |
| 4 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.14429380 |
| 5 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.12044115 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.00970337 |
| 7 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.80780213 |
| 8 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.53444560 |
| 9 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.50730833 |
| 10 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.50377064 |
| 11 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.49727385 |
| 12 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.44769598 |
| 13 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.43063901 |
| 14 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.38492279 |
| 15 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.32617185 |
| 16 | VDR_22108803_ChIP-Seq_LS180_Human | 2.29615459 |
| 17 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.28015848 |
| 18 | EWS_26573619_Chip-Seq_HEK293_Human | 2.27525174 |
| 19 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.26169794 |
| 20 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.24535589 |
| 21 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.22966840 |
| 22 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.21832209 |
| 23 | FUS_26573619_Chip-Seq_HEK293_Human | 2.20461703 |
| 24 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.19126550 |
| 25 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.16319885 |
| 26 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.14822623 |
| 27 | MYC_18940864_ChIP-ChIP_HL60_Human | 2.02971932 |
| 28 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.93909431 |
| 29 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.89497496 |
| 30 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.79218876 |
| 31 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.71715069 |
| 32 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.70910823 |
| 33 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.65573401 |
| 34 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.62967966 |
| 35 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.62967966 |
| 36 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.62505713 |
| 37 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.55378868 |
| 38 | P300_19829295_ChIP-Seq_ESCs_Human | 1.53957545 |
| 39 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.51339390 |
| 40 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.48918978 |
| 41 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.48877790 |
| 42 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.48216221 |
| 43 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.47609431 |
| 44 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.46632445 |
| 45 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.45210890 |
| 46 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.41317009 |
| 47 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.36512451 |
| 48 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.36201306 |
| 49 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.35052961 |
| 50 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.33274751 |
| 51 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.32586119 |
| 52 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.32237548 |
| 53 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.28838059 |
| 54 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.26423254 |
| 55 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.25419502 |
| 56 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.24370243 |
| 57 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.24370243 |
| 58 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.23833000 |
| 59 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.23784575 |
| 60 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.23227811 |
| 61 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.21328253 |
| 62 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.19825975 |
| 63 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.19621352 |
| 64 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.19040447 |
| 65 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.18439149 |
| 66 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.16822205 |
| 67 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.12824692 |
| 68 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.11287210 |
| 69 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.10852554 |
| 70 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.10187887 |
| 71 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.09858017 |
| 72 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.07086513 |
| 73 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.07036554 |
| 74 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.05355227 |
| 75 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.04875974 |
| 76 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.04837665 |
| 77 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.02400096 |
| 78 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.01421828 |
| 79 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.00608732 |
| 80 | AR_20517297_ChIP-Seq_VCAP_Human | 1.00293346 |
| 81 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.99993535 |
| 82 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.99090258 |
| 83 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.98641936 |
| 84 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.97830324 |
| 85 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.97040801 |
| 86 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.95856191 |
| 87 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.94459152 |
| 88 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.93061225 |
| 89 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.92332484 |
| 90 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.92284520 |
| 91 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.90994966 |
| 92 | NCOR_22424771_ChIP-Seq_293T_Human | 0.86758061 |
| 93 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.85091090 |
| 94 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.84600237 |
| 95 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.84477022 |
| 96 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.84139615 |
| 97 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.83574890 |
| 98 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.82667213 |
| 99 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.82364131 |
| 100 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.81910706 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003878_abnormal_ear_physiology | 3.74430218 |
| 2 | MP0005377_hearing/vestibular/ear_phenot | 3.74430218 |
| 3 | MP0008007_abnormal_cellular_replicative | 3.40013230 |
| 4 | MP0002102_abnormal_ear_morphology | 2.90200190 |
| 5 | MP0006292_abnormal_olfactory_placode | 2.52210124 |
| 6 | MP0002837_dystrophic_cardiac_calcinosis | 2.51924861 |
| 7 | MP0003718_maternal_effect | 2.49133738 |
| 8 | MP0003806_abnormal_nucleotide_metabolis | 2.44418652 |
| 9 | MP0003786_premature_aging | 2.35995151 |
| 10 | MP0008995_early_reproductive_senescence | 2.28259460 |
| 11 | MP0003136_yellow_coat_color | 2.23053228 |
| 12 | MP0010094_abnormal_chromosome_stability | 2.07458608 |
| 13 | MP0001485_abnormal_pinna_reflex | 2.06725123 |
| 14 | MP0005084_abnormal_gallbladder_morpholo | 2.04209534 |
| 15 | MP0006035_abnormal_mitochondrial_morpho | 2.02833180 |
| 16 | MP0003693_abnormal_embryo_hatching | 2.00661001 |
| 17 | MP0005670_abnormal_white_adipose | 1.94531192 |
| 18 | MP0002653_abnormal_ependyma_morphology | 1.88564665 |
| 19 | MP0002009_preneoplasia | 1.78936003 |
| 20 | MP0002160_abnormal_reproductive_system | 1.77583585 |
| 21 | MP0009333_abnormal_splenocyte_physiolog | 1.74534799 |
| 22 | MP0003195_calcinosis | 1.70802140 |
| 23 | MP0002006_tumorigenesis | 1.67123143 |
| 24 | MP0008789_abnormal_olfactory_epithelium | 1.66992688 |
| 25 | MP0002166_altered_tumor_susceptibility | 1.66432291 |
| 26 | MP0001835_abnormal_antigen_presentation | 1.65767904 |
| 27 | MP0005174_abnormal_tail_pigmentation | 1.65036994 |
| 28 | MP0004215_abnormal_myocardial_fiber | 1.62994879 |
| 29 | MP0008058_abnormal_DNA_repair | 1.62592033 |
| 30 | MP0003077_abnormal_cell_cycle | 1.52861661 |
| 31 | MP0000566_synostosis | 1.52193760 |
| 32 | MP0001764_abnormal_homeostasis | 1.51425640 |
| 33 | MP0000490_abnormal_crypts_of | 1.47775411 |
| 34 | MP0003937_abnormal_limbs/digits/tail_de | 1.46061028 |
| 35 | MP0000569_abnormal_digit_pigmentation | 1.45700712 |
| 36 | MP0008872_abnormal_physiological_respon | 1.43412866 |
| 37 | MP0003567_abnormal_fetal_cardiomyocyte | 1.40429574 |
| 38 | MP0003646_muscle_fatigue | 1.40195198 |
| 39 | MP0005083_abnormal_biliary_tract | 1.39685576 |
| 40 | MP0001293_anophthalmia | 1.38473032 |
| 41 | MP0000015_abnormal_ear_pigmentation | 1.38108738 |
| 42 | MP0008877_abnormal_DNA_methylation | 1.36271552 |
| 43 | MP0006072_abnormal_retinal_apoptosis | 1.35049372 |
| 44 | MP0002277_abnormal_respiratory_mucosa | 1.33566475 |
| 45 | MP0004957_abnormal_blastocyst_morpholog | 1.32297614 |
| 46 | MP0005075_abnormal_melanosome_morpholog | 1.29053449 |
| 47 | MP0006036_abnormal_mitochondrial_physio | 1.28449586 |
| 48 | MP0003172_abnormal_lysosome_physiology | 1.24935616 |
| 49 | MP0000383_abnormal_hair_follicle | 1.24930326 |
| 50 | MP0005389_reproductive_system_phenotype | 1.24436696 |
| 51 | MP0005085_abnormal_gallbladder_physiolo | 1.24038653 |
| 52 | MP0004084_abnormal_cardiac_muscle | 1.23009806 |
| 53 | MP0002095_abnormal_skin_pigmentation | 1.21654484 |
| 54 | MP0008057_abnormal_DNA_replication | 1.19705711 |
| 55 | MP0004145_abnormal_muscle_electrophysio | 1.14637090 |
| 56 | MP0002938_white_spotting | 1.14096672 |
| 57 | MP0005379_endocrine/exocrine_gland_phen | 1.11241635 |
| 58 | MP0003011_delayed_dark_adaptation | 1.09637152 |
| 59 | MP0005636_abnormal_mineral_homeostasis | 1.03978450 |
| 60 | MP0003315_abnormal_perineum_morphology | 1.03167471 |
| 61 | MP0000049_abnormal_middle_ear | 1.02629050 |
| 62 | MP0005394_taste/olfaction_phenotype | 1.02548414 |
| 63 | MP0005499_abnormal_olfactory_system | 1.02548414 |
| 64 | MP0004147_increased_porphyrin_level | 1.02093744 |
| 65 | MP0005408_hypopigmentation | 1.01123796 |
| 66 | MP0002249_abnormal_larynx_morphology | 0.97760066 |
| 67 | MP0002229_neurodegeneration | 0.97604782 |
| 68 | MP0003763_abnormal_thymus_physiology | 0.96273383 |
| 69 | MP0001348_abnormal_lacrimal_gland | 0.95663352 |
| 70 | MP0009250_abnormal_appendicular_skeleto | 0.95302426 |
| 71 | MP0009379_abnormal_foot_pigmentation | 0.95029594 |
| 72 | MP0005646_abnormal_pituitary_gland | 0.94729065 |
| 73 | MP0003123_paternal_imprinting | 0.94519821 |
| 74 | MP0005551_abnormal_eye_electrophysiolog | 0.94462274 |
| 75 | MP0001873_stomach_inflammation | 0.92960219 |
| 76 | MP0001919_abnormal_reproductive_system | 0.92498778 |
| 77 | MP0009384_cardiac_valve_regurgitation | 0.88187943 |
| 78 | MP0001529_abnormal_vocalization | 0.84595508 |
| 79 | MP0004484_altered_response_of | 0.83832892 |
| 80 | MP0008875_abnormal_xenobiotic_pharmacok | 0.79537753 |
| 81 | MP0000631_abnormal_neuroendocrine_gland | 0.78886927 |
| 82 | MP0000685_abnormal_immune_system | 0.77964728 |
| 83 | MP0001929_abnormal_gametogenesis | 0.77033864 |
| 84 | MP0002210_abnormal_sex_determination | 0.76604901 |
| 85 | MP0005253_abnormal_eye_physiology | 0.75721623 |
| 86 | MP0009046_muscle_twitch | 0.74627794 |
| 87 | MP0002177_abnormal_outer_ear | 0.72437375 |
| 88 | MP0001486_abnormal_startle_reflex | 0.69906936 |
| 89 | MP0001145_abnormal_male_reproductive | 0.69739410 |
| 90 | MP0002272_abnormal_nervous_system | 0.68954310 |
| 91 | MP0004885_abnormal_endolymph | 0.68686321 |
| 92 | MP0001963_abnormal_hearing_physiology | 0.68296868 |
| 93 | MP0002282_abnormal_trachea_morphology | 0.67077643 |
| 94 | MP0003137_abnormal_impulse_conducting | 0.66887014 |
| 95 | MP0003186_abnormal_redox_activity | 0.66621728 |
| 96 | MP0005266_abnormal_metabolism | 0.64693302 |
| 97 | MP0001661_extended_life_span | 0.63050859 |
| 98 | MP0004036_abnormal_muscle_relaxation | 0.63000292 |
| 99 | MP0008932_abnormal_embryonic_tissue | 0.62919338 |
| 100 | MP0003119_abnormal_digestive_system | 0.61017432 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Reduced antithrombin III activity (HP:0001976) | 3.95406018 |
| 2 | Type I transferrin isoform profile (HP:0003642) | 3.82732624 |
| 3 | True hermaphroditism (HP:0010459) | 3.55979444 |
| 4 | Increased hepatocellular lipid droplets (HP:0006565) | 3.52396884 |
| 5 | Pancreatic cysts (HP:0001737) | 3.33308906 |
| 6 | Acute necrotizing encephalopathy (HP:0006965) | 3.32800392 |
| 7 | Lipid accumulation in hepatocytes (HP:0006561) | 3.28131064 |
| 8 | Stomatitis (HP:0010280) | 3.07235487 |
| 9 | Renal Fanconi syndrome (HP:0001994) | 3.06126843 |
| 10 | Respiratory difficulties (HP:0002880) | 3.04680792 |
| 11 | Supernumerary spleens (HP:0009799) | 3.03126634 |
| 12 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.98982412 |
| 13 | Absent/shortened dynein arms (HP:0200106) | 2.98982412 |
| 14 | Chronic sinusitis (HP:0011109) | 2.94857000 |
| 15 | Abnormality of midbrain morphology (HP:0002418) | 2.94581662 |
| 16 | Molar tooth sign on MRI (HP:0002419) | 2.94581662 |
| 17 | Abnormal protein glycosylation (HP:0012346) | 2.94285755 |
| 18 | Abnormal glycosylation (HP:0012345) | 2.94285755 |
| 19 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.94285755 |
| 20 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.94285755 |
| 21 | Pancreatic fibrosis (HP:0100732) | 2.93828908 |
| 22 | Mitochondrial inheritance (HP:0001427) | 2.92259667 |
| 23 | Increased CSF lactate (HP:0002490) | 2.91647527 |
| 24 | Acute encephalopathy (HP:0006846) | 2.90688031 |
| 25 | Nephronophthisis (HP:0000090) | 2.90657240 |
| 26 | Abnormality of placental membranes (HP:0011409) | 2.88800929 |
| 27 | Amniotic constriction ring (HP:0009775) | 2.88800929 |
| 28 | Increased intramyocellular lipid droplets (HP:0012240) | 2.79909231 |
| 29 | Progressive macrocephaly (HP:0004481) | 2.68450722 |
| 30 | Abnormality of the intrinsic pathway (HP:0010989) | 2.68105638 |
| 31 | Colon cancer (HP:0003003) | 2.67260033 |
| 32 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.59759854 |
| 33 | Abnormality of urine glucose concentration (HP:0011016) | 2.54395002 |
| 34 | Glycosuria (HP:0003076) | 2.54395002 |
| 35 | Congenital stationary night blindness (HP:0007642) | 2.53706133 |
| 36 | Abnormal ciliary motility (HP:0012262) | 2.50852255 |
| 37 | Hyperglycinuria (HP:0003108) | 2.42179731 |
| 38 | Abnormality of the labia minora (HP:0012880) | 2.39602927 |
| 39 | Cerebral edema (HP:0002181) | 2.36422434 |
| 40 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.35135316 |
| 41 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.35135316 |
| 42 | Renal cortical cysts (HP:0000803) | 2.35082265 |
| 43 | Increased muscle lipid content (HP:0009058) | 2.27523591 |
| 44 | Exertional dyspnea (HP:0002875) | 2.26707322 |
| 45 | Abnormality of renal resorption (HP:0011038) | 2.23768632 |
| 46 | Pendular nystagmus (HP:0012043) | 2.20628349 |
| 47 | Abnormality of the renal medulla (HP:0100957) | 2.15892100 |
| 48 | Hypoplasia of the fovea (HP:0007750) | 2.12853478 |
| 49 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.12853478 |
| 50 | Abnormality of methionine metabolism (HP:0010901) | 2.11679769 |
| 51 | Increased serum lactate (HP:0002151) | 2.10748825 |
| 52 | Lethargy (HP:0001254) | 2.10409997 |
| 53 | Cerebral palsy (HP:0100021) | 2.09491969 |
| 54 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.08634065 |
| 55 | Methylmalonic acidemia (HP:0002912) | 2.07824859 |
| 56 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.07114702 |
| 57 | Severe visual impairment (HP:0001141) | 2.05899629 |
| 58 | Abnormality of the preputium (HP:0100587) | 2.04602913 |
| 59 | Confusion (HP:0001289) | 2.03905069 |
| 60 | Optic disc pallor (HP:0000543) | 2.03438075 |
| 61 | Meckel diverticulum (HP:0002245) | 2.02024604 |
| 62 | Brushfield spots (HP:0001088) | 2.02019739 |
| 63 | Cerebellar dysplasia (HP:0007033) | 2.01712015 |
| 64 | Male pseudohermaphroditism (HP:0000037) | 2.00121027 |
| 65 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.97622926 |
| 66 | Cystic liver disease (HP:0006706) | 1.97550356 |
| 67 | Hypoglycemic seizures (HP:0002173) | 1.97120941 |
| 68 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.96582090 |
| 69 | Bile duct proliferation (HP:0001408) | 1.94375512 |
| 70 | Abnormal biliary tract physiology (HP:0012439) | 1.94375512 |
| 71 | Adrenal hypoplasia (HP:0000835) | 1.93025198 |
| 72 | Abnormality of alanine metabolism (HP:0010916) | 1.92721853 |
| 73 | Hyperalaninemia (HP:0003348) | 1.92721853 |
| 74 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.92721853 |
| 75 | Hyperglycinemia (HP:0002154) | 1.92380195 |
| 76 | Abnormality of the ileum (HP:0001549) | 1.89260959 |
| 77 | Medial flaring of the eyebrow (HP:0010747) | 1.89013956 |
| 78 | Asplenia (HP:0001746) | 1.88263420 |
| 79 | Hyperphosphaturia (HP:0003109) | 1.87663905 |
| 80 | Abnormal pupillary function (HP:0007686) | 1.87440361 |
| 81 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.87196954 |
| 82 | Lactic acidosis (HP:0003128) | 1.87099684 |
| 83 | Methylmalonic aciduria (HP:0012120) | 1.87036954 |
| 84 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 1.87016097 |
| 85 | Abnormality of glycine metabolism (HP:0010895) | 1.85961429 |
| 86 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.85961429 |
| 87 | Abnormality of the anterior horn cell (HP:0006802) | 1.84591903 |
| 88 | Degeneration of anterior horn cells (HP:0002398) | 1.84591903 |
| 89 | Prolonged partial thromboplastin time (HP:0003645) | 1.84332702 |
| 90 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.83417671 |
| 91 | Ventricular fibrillation (HP:0001663) | 1.83204003 |
| 92 | Abnormality of the fovea (HP:0000493) | 1.81847799 |
| 93 | Stenosis of the external auditory canal (HP:0000402) | 1.81611564 |
| 94 | Sclerocornea (HP:0000647) | 1.81211758 |
| 95 | Central scotoma (HP:0000603) | 1.81007936 |
| 96 | Trismus (HP:0000211) | 1.80314981 |
| 97 | Esophageal atresia (HP:0002032) | 1.78468235 |
| 98 | Hepatocellular necrosis (HP:0001404) | 1.78198064 |
| 99 | Severe combined immunodeficiency (HP:0004430) | 1.78185749 |
| 100 | Congenital, generalized hypertrichosis (HP:0004540) | 1.78142405 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 4.48421125 |
| 2 | PBK | 4.46151608 |
| 3 | VRK1 | 2.91830867 |
| 4 | BUB1 | 2.75162572 |
| 5 | TAOK3 | 2.65563897 |
| 6 | BCKDK | 2.56651363 |
| 7 | GRK1 | 2.33887257 |
| 8 | MST4 | 2.31878808 |
| 9 | TSSK6 | 2.30142353 |
| 10 | MAP4K2 | 2.15097168 |
| 11 | EIF2AK3 | 1.96824755 |
| 12 | PLK3 | 1.94575353 |
| 13 | NUAK1 | 1.93462389 |
| 14 | NME1 | 1.80017941 |
| 15 | WEE1 | 1.69038605 |
| 16 | SRPK1 | 1.67284319 |
| 17 | PASK | 1.63896255 |
| 18 | ZAK | 1.63776868 |
| 19 | WNK3 | 1.61068454 |
| 20 | ADRBK2 | 1.57725369 |
| 21 | MKNK1 | 1.55635225 |
| 22 | STK16 | 1.55451811 |
| 23 | MAPK7 | 1.52997079 |
| 24 | BRSK2 | 1.50858202 |
| 25 | ACVR1B | 1.46471732 |
| 26 | MKNK2 | 1.43500062 |
| 27 | CDK3 | 1.41969428 |
| 28 | FRK | 1.36132268 |
| 29 | PLK2 | 1.32050711 |
| 30 | PLK4 | 1.27159351 |
| 31 | TRIM28 | 1.25231681 |
| 32 | TNK2 | 1.23336247 |
| 33 | PNCK | 1.22577695 |
| 34 | STK4 | 1.22508434 |
| 35 | PRKD3 | 1.21909943 |
| 36 | PINK1 | 1.18876111 |
| 37 | TAF1 | 1.18440934 |
| 38 | TESK1 | 1.13855035 |
| 39 | PDK2 | 1.10354977 |
| 40 | WNK4 | 1.05145263 |
| 41 | BMPR1B | 1.00276089 |
| 42 | EIF2AK1 | 0.99107576 |
| 43 | CAMKK2 | 0.97686349 |
| 44 | STK39 | 0.95162367 |
| 45 | CDC7 | 0.94762169 |
| 46 | NEK1 | 0.92650292 |
| 47 | INSRR | 0.83839725 |
| 48 | PRKCE | 0.82701284 |
| 49 | PIK3CG | 0.82682755 |
| 50 | RPS6KA4 | 0.81882488 |
| 51 | SCYL2 | 0.78283645 |
| 52 | MAPK13 | 0.77869171 |
| 53 | ATR | 0.77437021 |
| 54 | CSNK1G2 | 0.74075740 |
| 55 | CSNK1G3 | 0.72969489 |
| 56 | TXK | 0.72505123 |
| 57 | DYRK3 | 0.72379759 |
| 58 | TGFBR1 | 0.72325685 |
| 59 | CSNK1G1 | 0.71496088 |
| 60 | PLK1 | 0.68625797 |
| 61 | NEK9 | 0.66823874 |
| 62 | TIE1 | 0.58987708 |
| 63 | PAK3 | 0.57140803 |
| 64 | EIF2AK2 | 0.57067319 |
| 65 | AURKB | 0.56914896 |
| 66 | IKBKB | 0.56571547 |
| 67 | BMPR2 | 0.55038244 |
| 68 | SYK | 0.54609803 |
| 69 | OXSR1 | 0.52981766 |
| 70 | IGF1R | 0.52827829 |
| 71 | TNIK | 0.51712517 |
| 72 | ATM | 0.50934249 |
| 73 | MAP3K4 | 0.50873347 |
| 74 | PRKCG | 0.50252500 |
| 75 | JAK3 | 0.49271644 |
| 76 | STK38L | 0.47566075 |
| 77 | MAPK12 | 0.46391414 |
| 78 | MAP2K6 | 0.45141019 |
| 79 | CSNK2A1 | 0.44654662 |
| 80 | MAP3K5 | 0.44450647 |
| 81 | MAP2K7 | 0.44193616 |
| 82 | BRSK1 | 0.43103110 |
| 83 | CSNK1A1L | 0.42032391 |
| 84 | STK3 | 0.41704895 |
| 85 | TTK | 0.41535115 |
| 86 | MAP3K6 | 0.40967761 |
| 87 | CSNK1A1 | 0.38477594 |
| 88 | KIT | 0.38020130 |
| 89 | OBSCN | 0.37876360 |
| 90 | MAPK15 | 0.37581204 |
| 91 | CCNB1 | 0.37524793 |
| 92 | PRKDC | 0.37447422 |
| 93 | CASK | 0.36288155 |
| 94 | PIM1 | 0.35196491 |
| 95 | CHEK2 | 0.33995205 |
| 96 | CSNK2A2 | 0.33276624 |
| 97 | RPS6KB1 | 0.33007513 |
| 98 | CSNK1E | 0.31789054 |
| 99 | ADRBK1 | 0.29531632 |
| 100 | PRKCQ | 0.29356281 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.15586542 |
| 2 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 3.57951164 |
| 3 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.92200864 |
| 4 | RNA polymerase_Homo sapiens_hsa03020 | 2.82990534 |
| 5 | Ribosome_Homo sapiens_hsa03010 | 2.80346865 |
| 6 | Protein export_Homo sapiens_hsa03060 | 2.64004532 |
| 7 | RNA degradation_Homo sapiens_hsa03018 | 2.51211697 |
| 8 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.29192875 |
| 9 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.26366825 |
| 10 | Selenocompound metabolism_Homo sapiens_hsa00450 | 2.11534609 |
| 11 | Parkinsons disease_Homo sapiens_hsa05012 | 2.07815017 |
| 12 | Mismatch repair_Homo sapiens_hsa03430 | 1.99458930 |
| 13 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.81812111 |
| 14 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.77067212 |
| 15 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.74745744 |
| 16 | DNA replication_Homo sapiens_hsa03030 | 1.74093781 |
| 17 | RNA transport_Homo sapiens_hsa03013 | 1.72930105 |
| 18 | Basal transcription factors_Homo sapiens_hsa03022 | 1.66223905 |
| 19 | Retinol metabolism_Homo sapiens_hsa00830 | 1.64355579 |
| 20 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.60346022 |
| 21 | Peroxisome_Homo sapiens_hsa04146 | 1.57247779 |
| 22 | Spliceosome_Homo sapiens_hsa03040 | 1.54177113 |
| 23 | Asthma_Homo sapiens_hsa05310 | 1.52753313 |
| 24 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.52481570 |
| 25 | Homologous recombination_Homo sapiens_hsa03440 | 1.51503723 |
| 26 | Huntingtons disease_Homo sapiens_hsa05016 | 1.48686083 |
| 27 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.44082003 |
| 28 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.42001424 |
| 29 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.41902239 |
| 30 | Purine metabolism_Homo sapiens_hsa00230 | 1.39899613 |
| 31 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.36422961 |
| 32 | Alzheimers disease_Homo sapiens_hsa05010 | 1.36138430 |
| 33 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.31681649 |
| 34 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.30605399 |
| 35 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.27434610 |
| 36 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.27225256 |
| 37 | Allograft rejection_Homo sapiens_hsa05330 | 1.27225168 |
| 38 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.25985442 |
| 39 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.10218068 |
| 40 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.08365129 |
| 41 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.05951295 |
| 42 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.05071894 |
| 43 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.99216528 |
| 44 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.98527687 |
| 45 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.98027884 |
| 46 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.96468423 |
| 47 | Base excision repair_Homo sapiens_hsa03410 | 0.95566926 |
| 48 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.95163408 |
| 49 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.94770736 |
| 50 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.93041018 |
| 51 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.92846030 |
| 52 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.91725091 |
| 53 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.87483263 |
| 54 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.85979264 |
| 55 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.85553024 |
| 56 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.84516303 |
| 57 | Phototransduction_Homo sapiens_hsa04744 | 0.83373035 |
| 58 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.83359588 |
| 59 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.82329943 |
| 60 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.81517670 |
| 61 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.79970847 |
| 62 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.78786554 |
| 63 | Metabolic pathways_Homo sapiens_hsa01100 | 0.77766720 |
| 64 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.76932912 |
| 65 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.73777966 |
| 66 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.72597962 |
| 67 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.71102184 |
| 68 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.69738239 |
| 69 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.65930808 |
| 70 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.64589551 |
| 71 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.64483630 |
| 72 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.64122402 |
| 73 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.63892452 |
| 74 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.62307383 |
| 75 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.61986711 |
| 76 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.60679661 |
| 77 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.60102408 |
| 78 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.56191423 |
| 79 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.56169838 |
| 80 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.54485163 |
| 81 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.53176827 |
| 82 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.53008015 |
| 83 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.43041447 |
| 84 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.42850037 |
| 85 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.42315463 |
| 86 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.41240519 |
| 87 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.40202951 |
| 88 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.39381386 |
| 89 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.39174172 |
| 90 | Mineral absorption_Homo sapiens_hsa04978 | 0.38878911 |
| 91 | Cell cycle_Homo sapiens_hsa04110 | 0.37364959 |
| 92 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.36698447 |
| 93 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.35359697 |
| 94 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.35355391 |
| 95 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.32246730 |
| 96 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.32086462 |
| 97 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.31377257 |
| 98 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.28605266 |
| 99 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.27705200 |
| 100 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.27174508 |

