

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of natural killer cell differentiation (GO:0032825) | 7.16467714 |
| 2 | positive regulation of interleukin-17 production (GO:0032740) | 6.49667403 |
| 3 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.81467009 |
| 4 | cullin deneddylation (GO:0010388) | 4.86951039 |
| 5 | protein neddylation (GO:0045116) | 4.86869525 |
| 6 | DNA deamination (GO:0045006) | 4.75754707 |
| 7 | regulation of natural killer cell differentiation (GO:0032823) | 4.74048082 |
| 8 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 4.66748844 |
| 9 | positive regulation of tyrosine phosphorylation of Stat1 protein (GO:0042511) | 4.60781646 |
| 10 | regulation of chronic inflammatory response (GO:0002676) | 4.59225557 |
| 11 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.55486480 |
| 12 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.26091059 |
| 13 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.26091059 |
| 14 | protein deneddylation (GO:0000338) | 4.25157463 |
| 15 | lung secretory cell differentiation (GO:0061140) | 4.23239858 |
| 16 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 4.12422308 |
| 17 | viral mRNA export from host cell nucleus (GO:0046784) | 4.10815236 |
| 18 | inner mitochondrial membrane organization (GO:0007007) | 4.10766329 |
| 19 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 4.07944805 |
| 20 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.05257948 |
| 21 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.05250286 |
| 22 | regulation of interferon-gamma biosynthetic process (GO:0045072) | 4.03120969 |
| 23 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 4.02749923 |
| 24 | regulation of tyrosine phosphorylation of Stat1 protein (GO:0042510) | 3.96805981 |
| 25 | positive regulation of interleukin-10 production (GO:0032733) | 3.87727250 |
| 26 | rRNA modification (GO:0000154) | 3.81250944 |
| 27 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.76182580 |
| 28 | metallo-sulfur cluster assembly (GO:0031163) | 3.70427114 |
| 29 | iron-sulfur cluster assembly (GO:0016226) | 3.70427114 |
| 30 | rRNA methylation (GO:0031167) | 3.69625526 |
| 31 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.60927129 |
| 32 | regulation of interleukin-17 production (GO:0032660) | 3.53678516 |
| 33 | termination of RNA polymerase I transcription (GO:0006363) | 3.49547327 |
| 34 | maturation of 5.8S rRNA (GO:0000460) | 3.47480922 |
| 35 | respiratory chain complex IV assembly (GO:0008535) | 3.46899583 |
| 36 | regulation of interleukin-10 production (GO:0032653) | 3.46244393 |
| 37 | ribosome assembly (GO:0042255) | 3.38312943 |
| 38 | ribosome biogenesis (GO:0042254) | 3.36480306 |
| 39 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.35141919 |
| 40 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.34030070 |
| 41 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class | 3.33962305 |
| 42 | behavioral response to nicotine (GO:0035095) | 3.32885231 |
| 43 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.31627834 |
| 44 | cytidine deamination (GO:0009972) | 3.27108777 |
| 45 | cytidine metabolic process (GO:0046087) | 3.27108777 |
| 46 | cytidine catabolic process (GO:0006216) | 3.27108777 |
| 47 | negative regulation of telomere maintenance (GO:0032205) | 3.25153234 |
| 48 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.21313769 |
| 49 | ATP synthesis coupled proton transport (GO:0015986) | 3.21313769 |
| 50 | oxaloacetate metabolic process (GO:0006107) | 3.19755324 |
| 51 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.16432961 |
| 52 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 3.15817619 |
| 53 | DNA double-strand break processing (GO:0000729) | 3.15032289 |
| 54 | positive regulation of natural killer cell activation (GO:0032816) | 3.12989678 |
| 55 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.10749461 |
| 56 | transcription from mitochondrial promoter (GO:0006390) | 3.10452135 |
| 57 | mucosal-associated lymphoid tissue development (GO:0048537) | 3.09153229 |
| 58 | Peyers patch development (GO:0048541) | 3.09153229 |
| 59 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.04500194 |
| 60 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.04001899 |
| 61 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.04001899 |
| 62 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.04001899 |
| 63 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.03046930 |
| 64 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.03046930 |
| 65 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.00994073 |
| 66 | negative regulation of ligase activity (GO:0051352) | 3.00994073 |
| 67 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 2.98318215 |
| 68 | regulation of proton transport (GO:0010155) | 2.97331807 |
| 69 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.92872029 |
| 70 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.92872029 |
| 71 | cholesterol biosynthetic process (GO:0006695) | 2.92661146 |
| 72 | negative regulation of interleukin-10 production (GO:0032693) | 2.90218856 |
| 73 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.89758581 |
| 74 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.89060892 |
| 75 | negative regulation of B cell mediated immunity (GO:0002713) | 2.86688101 |
| 76 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 2.86688101 |
| 77 | leukocyte aggregation (GO:0070486) | 2.85959657 |
| 78 | L-fucose catabolic process (GO:0042355) | 2.83285339 |
| 79 | fucose catabolic process (GO:0019317) | 2.83285339 |
| 80 | L-fucose metabolic process (GO:0042354) | 2.83285339 |
| 81 | negative regulation of DNA recombination (GO:0045910) | 2.82690008 |
| 82 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.78851437 |
| 83 | mitochondrial RNA metabolic process (GO:0000959) | 2.78759571 |
| 84 | regulation of cellular amine metabolic process (GO:0033238) | 2.77698931 |
| 85 | protein targeting to mitochondrion (GO:0006626) | 2.75513795 |
| 86 | positive regulation of heterotypic cell-cell adhesion (GO:0034116) | 2.74639863 |
| 87 | positive regulation of cardiac muscle cell differentiation (GO:2000727) | 2.74273352 |
| 88 | isoprenoid biosynthetic process (GO:0008299) | 2.72466364 |
| 89 | T cell lineage commitment (GO:0002360) | 2.70478101 |
| 90 | tRNA processing (GO:0008033) | 2.68976398 |
| 91 | attachment of spindle microtubules to kinetochore (GO:0008608) | 2.68416847 |
| 92 | transcription initiation from RNA polymerase I promoter (GO:0006361) | 2.66543401 |
| 93 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.66328271 |
| 94 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.66328271 |
| 95 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.63030492 |
| 96 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.63030492 |
| 97 | NADH dehydrogenase complex assembly (GO:0010257) | 2.63030492 |
| 98 | amino acid activation (GO:0043038) | 2.62835881 |
| 99 | tRNA aminoacylation (GO:0043039) | 2.62835881 |
| 100 | positive regulation of cell fate commitment (GO:0010455) | 2.62806697 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 6.05986298 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 5.84848549 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.27577667 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.52688459 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.78412344 |
| 6 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.73792888 |
| 7 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 3.69071323 |
| 8 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.58021875 |
| 9 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.40839763 |
| 10 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.34146899 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.16705598 |
| 12 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.14259111 |
| 13 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.95777407 |
| 14 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.71460682 |
| 15 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.65302077 |
| 16 | VDR_22108803_ChIP-Seq_LS180_Human | 2.63285587 |
| 17 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.60075372 |
| 18 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.41929344 |
| 19 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.27855567 |
| 20 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.21574193 |
| 21 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 2.06114621 |
| 22 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.04811085 |
| 23 | GABP_19822575_ChIP-Seq_HepG2_Human | 2.00858094 |
| 24 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.97578332 |
| 25 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.93282964 |
| 26 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.87269795 |
| 27 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.83845095 |
| 28 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.80919613 |
| 29 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.75371066 |
| 30 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.73941545 |
| 31 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.72781828 |
| 32 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.71654519 |
| 33 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.69238111 |
| 34 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.66662279 |
| 35 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.63760928 |
| 36 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.62527422 |
| 37 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.58205679 |
| 38 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.57968584 |
| 39 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.57714942 |
| 40 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.50487952 |
| 41 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.49100647 |
| 42 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.45075842 |
| 43 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.42705631 |
| 44 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.39768189 |
| 45 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.35174978 |
| 46 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.30663224 |
| 47 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.29492652 |
| 48 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.26268480 |
| 49 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.24622009 |
| 50 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.24051961 |
| 51 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.23440630 |
| 52 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.20324457 |
| 53 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.19913812 |
| 54 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.18695550 |
| 55 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.17153638 |
| 56 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.16363316 |
| 57 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.16021017 |
| 58 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.11123428 |
| 59 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.10503358 |
| 60 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.09286158 |
| 61 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.08817064 |
| 62 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.08030721 |
| 63 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.07554294 |
| 64 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.06551996 |
| 65 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.05312280 |
| 66 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.02527550 |
| 67 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.00163520 |
| 68 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.98717117 |
| 69 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.97932172 |
| 70 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.97932172 |
| 71 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.92259116 |
| 72 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.91528658 |
| 73 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.88719534 |
| 74 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.85653957 |
| 75 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.84012946 |
| 76 | GATA3_26560356_Chip-Seq_TH2_Human | 0.84004805 |
| 77 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.83876722 |
| 78 | NCOR_22424771_ChIP-Seq_293T_Human | 0.82502766 |
| 79 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.81989800 |
| 80 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.81539846 |
| 81 | P300_19829295_ChIP-Seq_ESCs_Human | 0.81291454 |
| 82 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.78413529 |
| 83 | GATA1_22025678_ChIP-Seq_K562_Human | 0.78333557 |
| 84 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.77149217 |
| 85 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.76795926 |
| 86 | EWS_26573619_Chip-Seq_HEK293_Human | 0.76298091 |
| 87 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.75884409 |
| 88 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.75214318 |
| 89 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 0.73985328 |
| 90 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.72158807 |
| 91 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.70129922 |
| 92 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.69964084 |
| 93 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.69910742 |
| 94 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.69691990 |
| 95 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.68979166 |
| 96 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.68464461 |
| 97 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.67361225 |
| 98 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.66139948 |
| 99 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.65576398 |
| 100 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.65433824 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0010386_abnormal_urinary_bladder | 3.28090943 |
| 2 | MP0001348_abnormal_lacrimal_gland | 3.20479299 |
| 3 | MP0002102_abnormal_ear_morphology | 3.10414460 |
| 4 | MP0004145_abnormal_muscle_electrophysio | 3.06791058 |
| 5 | MP0002138_abnormal_hepatobiliary_system | 3.05312068 |
| 6 | MP0001873_stomach_inflammation | 3.02774096 |
| 7 | MP0004147_increased_porphyrin_level | 3.00680514 |
| 8 | MP0008877_abnormal_DNA_methylation | 2.85853811 |
| 9 | MP0008995_early_reproductive_senescence | 2.77394606 |
| 10 | MP0003786_premature_aging | 2.58355990 |
| 11 | MP0003646_muscle_fatigue | 2.46554154 |
| 12 | MP0004742_abnormal_vestibular_system | 2.24264444 |
| 13 | MP0002638_abnormal_pupillary_reflex | 2.23186607 |
| 14 | MP0006292_abnormal_olfactory_placode | 2.21084744 |
| 15 | MP0005645_abnormal_hypothalamus_physiol | 2.15215010 |
| 16 | MP0002822_catalepsy | 2.09819225 |
| 17 | MP0008872_abnormal_physiological_respon | 2.08906320 |
| 18 | MP0003693_abnormal_embryo_hatching | 2.06109113 |
| 19 | MP0003718_maternal_effect | 2.05208373 |
| 20 | MP0008058_abnormal_DNA_repair | 2.00375409 |
| 21 | MP0001188_hyperpigmentation | 1.99188296 |
| 22 | MP0003567_abnormal_fetal_cardiomyocyte | 1.98577709 |
| 23 | MP0005084_abnormal_gallbladder_morpholo | 1.98119119 |
| 24 | MP0008961_abnormal_basal_metabolism | 1.87034282 |
| 25 | MP0001984_abnormal_olfaction | 1.82723335 |
| 26 | MP0001790_abnormal_immune_system | 1.77582194 |
| 27 | MP0005387_immune_system_phenotype | 1.77582194 |
| 28 | MP0009697_abnormal_copulation | 1.67695062 |
| 29 | MP0001502_abnormal_circadian_rhythm | 1.55581910 |
| 30 | MP0001835_abnormal_antigen_presentation | 1.49458618 |
| 31 | MP0003122_maternal_imprinting | 1.46859749 |
| 32 | MP0005167_abnormal_blood-brain_barrier | 1.46497130 |
| 33 | MP0008057_abnormal_DNA_replication | 1.45271356 |
| 34 | MP0004142_abnormal_muscle_tone | 1.45268734 |
| 35 | MP0008875_abnormal_xenobiotic_pharmacok | 1.43300950 |
| 36 | MP0001968_abnormal_touch/_nociception | 1.42307652 |
| 37 | MP0005085_abnormal_gallbladder_physiolo | 1.39928224 |
| 38 | MP0002876_abnormal_thyroid_physiology | 1.39492542 |
| 39 | MP0009745_abnormal_behavioral_response | 1.36393904 |
| 40 | MP0001501_abnormal_sleep_pattern | 1.32390394 |
| 41 | MP0005646_abnormal_pituitary_gland | 1.31511031 |
| 42 | MP0003878_abnormal_ear_physiology | 1.27936868 |
| 43 | MP0005377_hearing/vestibular/ear_phenot | 1.27936868 |
| 44 | MP0006276_abnormal_autonomic_nervous | 1.25172662 |
| 45 | MP0000372_irregular_coat_pigmentation | 1.24103460 |
| 46 | MP0001529_abnormal_vocalization | 1.23385690 |
| 47 | MP0005187_abnormal_penis_morphology | 1.23006021 |
| 48 | MP0006072_abnormal_retinal_apoptosis | 1.21814549 |
| 49 | MP0008789_abnormal_olfactory_epithelium | 1.19422198 |
| 50 | MP0005499_abnormal_olfactory_system | 1.19263356 |
| 51 | MP0005394_taste/olfaction_phenotype | 1.19263356 |
| 52 | MP0002163_abnormal_gland_morphology | 1.12735758 |
| 53 | MP0002006_tumorigenesis | 1.12529696 |
| 54 | MP0005647_abnormal_sex_gland | 1.11378656 |
| 55 | MP0001905_abnormal_dopamine_level | 1.11256128 |
| 56 | MP0001919_abnormal_reproductive_system | 1.09719483 |
| 57 | MP0000685_abnormal_immune_system | 1.09519782 |
| 58 | MP0004957_abnormal_blastocyst_morpholog | 1.09115365 |
| 59 | MP0003866_abnormal_defecation | 1.01271075 |
| 60 | MP0003763_abnormal_thymus_physiology | 0.98333606 |
| 61 | MP0005671_abnormal_response_to | 0.97754469 |
| 62 | MP0001663_abnormal_digestive_system | 0.97126641 |
| 63 | MP0005365_abnormal_bile_salt | 0.96877498 |
| 64 | MP0004133_heterotaxia | 0.95784891 |
| 65 | MP0002736_abnormal_nociception_after | 0.95781269 |
| 66 | MP0002938_white_spotting | 0.93798106 |
| 67 | MP0002928_abnormal_bile_duct | 0.92414967 |
| 68 | MP0003880_abnormal_central_pattern | 0.90102272 |
| 69 | MP0001243_abnormal_dermal_layer | 0.90064106 |
| 70 | MP0005551_abnormal_eye_electrophysiolog | 0.88908192 |
| 71 | MP0005410_abnormal_fertilization | 0.84649433 |
| 72 | MP0003119_abnormal_digestive_system | 0.84282709 |
| 73 | MP0006036_abnormal_mitochondrial_physio | 0.83747582 |
| 74 | MP0006082_CNS_inflammation | 0.81231631 |
| 75 | MP0000631_abnormal_neuroendocrine_gland | 0.80951587 |
| 76 | MP0001986_abnormal_taste_sensitivity | 0.80639087 |
| 77 | MP0001764_abnormal_homeostasis | 0.77899856 |
| 78 | MP0002272_abnormal_nervous_system | 0.77616595 |
| 79 | MP0003936_abnormal_reproductive_system | 0.76361066 |
| 80 | MP0001485_abnormal_pinna_reflex | 0.76176667 |
| 81 | MP0010094_abnormal_chromosome_stability | 0.75946961 |
| 82 | MP0002139_abnormal_hepatobiliary_system | 0.75286757 |
| 83 | MP0005389_reproductive_system_phenotype | 0.75021119 |
| 84 | MP0002166_altered_tumor_susceptibility | 0.74231460 |
| 85 | MP0009333_abnormal_splenocyte_physiolog | 0.74037320 |
| 86 | MP0000465_gastrointestinal_hemorrhage | 0.73498440 |
| 87 | MP0000013_abnormal_adipose_tissue | 0.72885695 |
| 88 | MP0001800_abnormal_humoral_immune | 0.71396337 |
| 89 | MP0004085_abnormal_heartbeat | 0.68855586 |
| 90 | MP0000627_abnormal_mammary_gland | 0.68544571 |
| 91 | MP0003959_abnormal_lean_body | 0.67821405 |
| 92 | MP0002277_abnormal_respiratory_mucosa | 0.67003915 |
| 93 | MP0005310_abnormal_salivary_gland | 0.65362557 |
| 94 | MP0003137_abnormal_impulse_conducting | 0.64596713 |
| 95 | MP0005636_abnormal_mineral_homeostasis | 0.64210724 |
| 96 | MP0005381_digestive/alimentary_phenotyp | 0.60799183 |
| 97 | MP0005000_abnormal_immune_tolerance | 0.59510227 |
| 98 | MP0005220_abnormal_exocrine_pancreas | 0.59145297 |
| 99 | MP0003879_abnormal_hair_cell | 0.57886034 |
| 100 | MP0000538_abnormal_urinary_bladder | 0.56837064 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Aplastic anemia (HP:0001915) | 5.80625143 |
| 2 | Increased intramyocellular lipid droplets (HP:0012240) | 4.44499701 |
| 3 | Increased hepatocellular lipid droplets (HP:0006565) | 4.19088438 |
| 4 | Mitochondrial inheritance (HP:0001427) | 3.89972693 |
| 5 | Increased CSF lactate (HP:0002490) | 3.89146558 |
| 6 | Lipid accumulation in hepatocytes (HP:0006561) | 3.83183357 |
| 7 | Abnormality of alanine metabolism (HP:0010916) | 3.80401288 |
| 8 | Hyperalaninemia (HP:0003348) | 3.80401288 |
| 9 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.80401288 |
| 10 | Acute necrotizing encephalopathy (HP:0006965) | 3.72677767 |
| 11 | Increased muscle lipid content (HP:0009058) | 3.68135350 |
| 12 | Increased serum pyruvate (HP:0003542) | 3.64169222 |
| 13 | Abnormality of glycolysis (HP:0004366) | 3.63684441 |
| 14 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.63103983 |
| 15 | Exertional dyspnea (HP:0002875) | 3.31869301 |
| 16 | Abnormality of the labia minora (HP:0012880) | 3.30562916 |
| 17 | Hepatocellular necrosis (HP:0001404) | 3.26378298 |
| 18 | Chronic diarrhea (HP:0002028) | 3.24639281 |
| 19 | Hepatic necrosis (HP:0002605) | 3.06653657 |
| 20 | Acute encephalopathy (HP:0006846) | 3.01766646 |
| 21 | Abnormality of the pons (HP:0007361) | 2.99439033 |
| 22 | Increased serum lactate (HP:0002151) | 2.96510155 |
| 23 | Progressive macrocephaly (HP:0004481) | 2.95898091 |
| 24 | Parakeratosis (HP:0001036) | 2.94167172 |
| 25 | Multiple enchondromatosis (HP:0005701) | 2.86254097 |
| 26 | Hypoplasia of the pons (HP:0012110) | 2.81052833 |
| 27 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.80948817 |
| 28 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.80948817 |
| 29 | Thyroid-stimulating hormone excess (HP:0002925) | 2.78357210 |
| 30 | Pendular nystagmus (HP:0012043) | 2.78273584 |
| 31 | Methylmalonic aciduria (HP:0012120) | 2.77813318 |
| 32 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.76043163 |
| 33 | Renal Fanconi syndrome (HP:0001994) | 2.69721353 |
| 34 | Oral leukoplakia (HP:0002745) | 2.66884867 |
| 35 | Abolished electroretinogram (ERG) (HP:0000550) | 2.63498186 |
| 36 | Pancreatic cysts (HP:0001737) | 2.61600473 |
| 37 | Respiratory difficulties (HP:0002880) | 2.60183941 |
| 38 | Optic disc pallor (HP:0000543) | 2.57252619 |
| 39 | Unilateral renal agenesis (HP:0000122) | 2.44183525 |
| 40 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.37854771 |
| 41 | Lactic acidosis (HP:0003128) | 2.37552547 |
| 42 | Colon cancer (HP:0003003) | 2.37006487 |
| 43 | Cerebral edema (HP:0002181) | 2.32418016 |
| 44 | Adactyly (HP:0009776) | 2.31506150 |
| 45 | Abnormality of DNA repair (HP:0003254) | 2.30186408 |
| 46 | Genetic anticipation (HP:0003743) | 2.27980024 |
| 47 | Respiratory failure (HP:0002878) | 2.26226446 |
| 48 | Tubulointerstitial nephritis (HP:0001970) | 2.25339671 |
| 49 | Hyperglycinemia (HP:0002154) | 2.24741844 |
| 50 | Neonatal respiratory distress (HP:0002643) | 2.23764411 |
| 51 | Pancytopenia (HP:0001876) | 2.21996316 |
| 52 | IgG deficiency (HP:0004315) | 2.19791573 |
| 53 | Abnormality of serum amino acid levels (HP:0003112) | 2.18329149 |
| 54 | Abnormality of B cell number (HP:0010975) | 2.17519578 |
| 55 | Neuroblastoma (HP:0003006) | 2.16199349 |
| 56 | Primitive neuroectodermal tumor (HP:0030065) | 2.16199349 |
| 57 | Neuroblastic tumors (HP:0004376) | 2.16199349 |
| 58 | Peripheral primitive neuroectodermal neoplasm (HP:0030067) | 2.16199349 |
| 59 | B lymphocytopenia (HP:0010976) | 2.13792283 |
| 60 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.08634749 |
| 61 | Lethargy (HP:0001254) | 2.08615571 |
| 62 | Abnormal biliary tract physiology (HP:0012439) | 2.05336915 |
| 63 | Bile duct proliferation (HP:0001408) | 2.05336915 |
| 64 | Cerebellar dysplasia (HP:0007033) | 2.03676820 |
| 65 | Methylmalonic acidemia (HP:0002912) | 2.00565107 |
| 66 | Glycosuria (HP:0003076) | 1.99132097 |
| 67 | Abnormality of urine glucose concentration (HP:0011016) | 1.99132097 |
| 68 | Thyroiditis (HP:0100646) | 1.98609171 |
| 69 | Abnormality of glycine metabolism (HP:0010895) | 1.97653010 |
| 70 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.97653010 |
| 71 | Megalencephaly (HP:0001355) | 1.96076944 |
| 72 | Exercise intolerance (HP:0003546) | 1.95192695 |
| 73 | Severe combined immunodeficiency (HP:0004430) | 1.94587737 |
| 74 | CNS demyelination (HP:0007305) | 1.92033867 |
| 75 | Neoplasm of the adrenal gland (HP:0100631) | 1.91723616 |
| 76 | Hyperphosphaturia (HP:0003109) | 1.89572086 |
| 77 | Hypoproteinemia (HP:0003075) | 1.86268693 |
| 78 | Constricted visual fields (HP:0001133) | 1.84653804 |
| 79 | Severe muscular hypotonia (HP:0006829) | 1.84197042 |
| 80 | Increased IgM level (HP:0003496) | 1.84160378 |
| 81 | Pancreatic fibrosis (HP:0100732) | 1.83309861 |
| 82 | Duplicated collecting system (HP:0000081) | 1.83010037 |
| 83 | Type II lissencephaly (HP:0007260) | 1.81752176 |
| 84 | True hermaphroditism (HP:0010459) | 1.79568122 |
| 85 | Chorioretinal atrophy (HP:0000533) | 1.79121525 |
| 86 | Microvesicular hepatic steatosis (HP:0001414) | 1.78690115 |
| 87 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.76792177 |
| 88 | Cerebral palsy (HP:0100021) | 1.72927523 |
| 89 | Nephronophthisis (HP:0000090) | 1.71561692 |
| 90 | Hyperglycinuria (HP:0003108) | 1.71267999 |
| 91 | Cystic liver disease (HP:0006706) | 1.70350347 |
| 92 | Abnormality of the renal collecting system (HP:0004742) | 1.69897789 |
| 93 | Optic nerve coloboma (HP:0000588) | 1.69794016 |
| 94 | Papillary thyroid carcinoma (HP:0002895) | 1.69618953 |
| 95 | Upper limb muscle weakness (HP:0003484) | 1.67925650 |
| 96 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.67820150 |
| 97 | Cerebral hypomyelination (HP:0006808) | 1.66960262 |
| 98 | Abnormality of the anterior horn cell (HP:0006802) | 1.64039929 |
| 99 | Degeneration of anterior horn cells (HP:0002398) | 1.64039929 |
| 100 | Fused cervical vertebrae (HP:0002949) | 1.62742975 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STK16 | 5.51132145 |
| 2 | TSSK6 | 4.83293191 |
| 3 | EIF2AK3 | 3.59840076 |
| 4 | EIF2AK1 | 3.48614137 |
| 5 | BUB1 | 3.36690837 |
| 6 | NEK1 | 3.19156416 |
| 7 | TLK1 | 2.97956375 |
| 8 | ZAK | 2.50190445 |
| 9 | VRK2 | 2.29012835 |
| 10 | BCKDK | 2.14322037 |
| 11 | PBK | 2.13505417 |
| 12 | TAF1 | 2.01771965 |
| 13 | MAP4K2 | 1.99024396 |
| 14 | SRPK1 | 1.93600187 |
| 15 | PAK6 | 1.89569555 |
| 16 | CDK8 | 1.87937061 |
| 17 | BCR | 1.69045096 |
| 18 | SIK3 | 1.63014664 |
| 19 | VRK1 | 1.60769824 |
| 20 | PDK2 | 1.54291792 |
| 21 | ADRBK2 | 1.44376033 |
| 22 | BMPR1B | 1.40253357 |
| 23 | CSNK1A1L | 1.36421467 |
| 24 | WNK4 | 1.30765607 |
| 25 | DYRK2 | 1.27200974 |
| 26 | PAK3 | 1.16433182 |
| 27 | PLK3 | 1.16271847 |
| 28 | GRK1 | 1.13755517 |
| 29 | NUAK1 | 1.11872395 |
| 30 | MST4 | 1.10861988 |
| 31 | CSNK1G1 | 1.09569398 |
| 32 | CSNK1G3 | 1.06914750 |
| 33 | FRK | 1.04204870 |
| 34 | EPHA4 | 1.01864916 |
| 35 | RAF1 | 0.98400254 |
| 36 | NME1 | 0.95634953 |
| 37 | MAP3K12 | 0.92778472 |
| 38 | KDR | 0.90117624 |
| 39 | PHKG1 | 0.87304648 |
| 40 | PHKG2 | 0.87304648 |
| 41 | TXK | 0.87165923 |
| 42 | ALK | 0.86643496 |
| 43 | CSNK1G2 | 0.85543270 |
| 44 | CLK1 | 0.85103910 |
| 45 | CDC7 | 0.82552938 |
| 46 | MKNK1 | 0.81692168 |
| 47 | MAP2K6 | 0.78311050 |
| 48 | TAOK3 | 0.74246302 |
| 49 | PRKAA2 | 0.74166879 |
| 50 | WNK3 | 0.71058899 |
| 51 | RPS6KA5 | 0.69998216 |
| 52 | CSNK1E | 0.68555171 |
| 53 | ATR | 0.67747237 |
| 54 | CAMKK2 | 0.65717541 |
| 55 | AURKB | 0.61758724 |
| 56 | TRIM28 | 0.60897756 |
| 57 | EIF2AK2 | 0.59889859 |
| 58 | CDK9 | 0.57843933 |
| 59 | MKNK2 | 0.56454561 |
| 60 | AKT2 | 0.56261630 |
| 61 | PLK1 | 0.55907884 |
| 62 | DAPK1 | 0.55501273 |
| 63 | AURKA | 0.54016586 |
| 64 | INSRR | 0.52064291 |
| 65 | CSNK1A1 | 0.51398643 |
| 66 | STK24 | 0.50154163 |
| 67 | ITK | 0.48753067 |
| 68 | LIMK1 | 0.48632146 |
| 69 | CSNK2A2 | 0.48280933 |
| 70 | CAMK2A | 0.47893661 |
| 71 | SIK2 | 0.47397351 |
| 72 | CDK4 | 0.45605954 |
| 73 | CSNK1D | 0.44267775 |
| 74 | PRKCG | 0.44007412 |
| 75 | PAK1 | 0.43059326 |
| 76 | CCNB1 | 0.38799201 |
| 77 | TESK2 | 0.37844680 |
| 78 | MAPKAPK5 | 0.37573871 |
| 79 | PRKCQ | 0.35778365 |
| 80 | GRK5 | 0.34410356 |
| 81 | PRKCB | 0.33295816 |
| 82 | SGK1 | 0.33275478 |
| 83 | DAPK3 | 0.32941122 |
| 84 | MAPK13 | 0.32767843 |
| 85 | PRKAA1 | 0.32752953 |
| 86 | STK39 | 0.32621622 |
| 87 | CHEK1 | 0.32380733 |
| 88 | OXSR1 | 0.32248813 |
| 89 | KSR2 | 0.31875214 |
| 90 | CSNK2A1 | 0.31136933 |
| 91 | STK38L | 0.30607396 |
| 92 | PRKACA | 0.30022433 |
| 93 | BTK | 0.28494210 |
| 94 | IKBKB | 0.28024308 |
| 95 | MYLK | 0.27812819 |
| 96 | ATM | 0.26457877 |
| 97 | PRKCA | 0.26085143 |
| 98 | PRKACB | 0.25470959 |
| 99 | NEK2 | 0.24290592 |
| 100 | LCK | 0.23795596 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.68026018 |
| 2 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.28356035 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.98499565 |
| 4 | Protein export_Homo sapiens_hsa03060 | 2.93105664 |
| 5 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.92255975 |
| 6 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.84643065 |
| 7 | Parkinsons disease_Homo sapiens_hsa05012 | 2.66300255 |
| 8 | RNA polymerase_Homo sapiens_hsa03020 | 2.59974885 |
| 9 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.25973266 |
| 10 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.10038816 |
| 11 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.09637176 |
| 12 | RNA transport_Homo sapiens_hsa03013 | 1.99835940 |
| 13 | Spliceosome_Homo sapiens_hsa03040 | 1.95953290 |
| 14 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.94164204 |
| 15 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.88037623 |
| 16 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.82457602 |
| 17 | Basal transcription factors_Homo sapiens_hsa03022 | 1.82432811 |
| 18 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.78017738 |
| 19 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.77751547 |
| 20 | Mismatch repair_Homo sapiens_hsa03430 | 1.77105503 |
| 21 | DNA replication_Homo sapiens_hsa03030 | 1.68813265 |
| 22 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.68372398 |
| 23 | Sulfur relay system_Homo sapiens_hsa04122 | 1.65122851 |
| 24 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.62704975 |
| 25 | Huntingtons disease_Homo sapiens_hsa05016 | 1.61982089 |
| 26 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.54047508 |
| 27 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.45275027 |
| 28 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.45045486 |
| 29 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.44797188 |
| 30 | RNA degradation_Homo sapiens_hsa03018 | 1.42974865 |
| 31 | Alzheimers disease_Homo sapiens_hsa05010 | 1.34181736 |
| 32 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.33995735 |
| 33 | Base excision repair_Homo sapiens_hsa03410 | 1.30810867 |
| 34 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.27574510 |
| 35 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.25892215 |
| 36 | Phototransduction_Homo sapiens_hsa04744 | 1.25167967 |
| 37 | Homologous recombination_Homo sapiens_hsa03440 | 1.20362029 |
| 38 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.17528680 |
| 39 | Alcoholism_Homo sapiens_hsa05034 | 1.08318408 |
| 40 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.06997286 |
| 41 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.06465164 |
| 42 | Ribosome_Homo sapiens_hsa03010 | 1.00586026 |
| 43 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.99590100 |
| 44 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.99187500 |
| 45 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.95039024 |
| 46 | Allograft rejection_Homo sapiens_hsa05330 | 0.92047311 |
| 47 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.87735920 |
| 48 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.87721171 |
| 49 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.86458827 |
| 50 | Peroxisome_Homo sapiens_hsa04146 | 0.85390549 |
| 51 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.84536248 |
| 52 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.84515387 |
| 53 | Asthma_Homo sapiens_hsa05310 | 0.83614227 |
| 54 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.80942384 |
| 55 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.79333173 |
| 56 | Purine metabolism_Homo sapiens_hsa00230 | 0.79032159 |
| 57 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.75735695 |
| 58 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.73386256 |
| 59 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.70260311 |
| 60 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.66819847 |
| 61 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.65091680 |
| 62 | Carbon metabolism_Homo sapiens_hsa01200 | 0.64410025 |
| 63 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.63626968 |
| 64 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.63260374 |
| 65 | Metabolic pathways_Homo sapiens_hsa01100 | 0.63185301 |
| 66 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.62033922 |
| 67 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.59732492 |
| 68 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.56895821 |
| 69 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.54652663 |
| 70 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.52545177 |
| 71 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.52392707 |
| 72 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.48135210 |
| 73 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.47255869 |
| 74 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.46732674 |
| 75 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.46586156 |
| 76 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.46480149 |
| 77 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.45709455 |
| 78 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.45470404 |
| 79 | Mineral absorption_Homo sapiens_hsa04978 | 0.44363122 |
| 80 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.43668139 |
| 81 | Cell cycle_Homo sapiens_hsa04110 | 0.41721614 |
| 82 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.40754303 |
| 83 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.39737088 |
| 84 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.39663229 |
| 85 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.39264483 |
| 86 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.39222323 |
| 87 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.37109867 |
| 88 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.34878016 |
| 89 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.34575316 |
| 90 | Retinol metabolism_Homo sapiens_hsa00830 | 0.33827156 |
| 91 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.31075567 |
| 92 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.30882943 |
| 93 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.30615084 |
| 94 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.29734392 |
| 95 | Nicotine addiction_Homo sapiens_hsa05033 | 0.28853557 |
| 96 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.27557513 |
| 97 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.24277077 |
| 98 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.24080911 |
| 99 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.23868456 |
| 100 | Legionellosis_Homo sapiens_hsa05134 | 0.23222858 |

