

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 6.42795897 |
| 2 | cytidine metabolic process (GO:0046087) | 4.88297195 |
| 3 | cytidine catabolic process (GO:0006216) | 4.88297195 |
| 4 | cytidine deamination (GO:0009972) | 4.88297195 |
| 5 | proteasome assembly (GO:0043248) | 4.77318554 |
| 6 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.60955305 |
| 7 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.60055159 |
| 8 | ATP synthesis coupled proton transport (GO:0015986) | 4.19395897 |
| 9 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.19395897 |
| 10 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.11093889 |
| 11 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.96214286 |
| 12 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.80934485 |
| 13 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.79569385 |
| 14 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.77170108 |
| 15 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.74063005 |
| 16 | respiratory chain complex IV assembly (GO:0008535) | 3.69478520 |
| 17 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.57458815 |
| 18 | platelet dense granule organization (GO:0060155) | 3.55644463 |
| 19 | protein complex biogenesis (GO:0070271) | 3.53619874 |
| 20 | protein neddylation (GO:0045116) | 3.53190336 |
| 21 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.50979105 |
| 22 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.50979105 |
| 23 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.50979105 |
| 24 | respiratory electron transport chain (GO:0022904) | 3.49051836 |
| 25 | electron transport chain (GO:0022900) | 3.46036345 |
| 26 | rRNA modification (GO:0000154) | 3.46033087 |
| 27 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.45614893 |
| 28 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.45440410 |
| 29 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.45440410 |
| 30 | negative regulation of ligase activity (GO:0051352) | 3.38687373 |
| 31 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.38687373 |
| 32 | cytochrome complex assembly (GO:0017004) | 3.34671845 |
| 33 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.30154990 |
| 34 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.30154990 |
| 35 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.29969114 |
| 36 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.28165281 |
| 37 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.27051459 |
| 38 | chaperone-mediated protein transport (GO:0072321) | 3.24211506 |
| 39 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.17372447 |
| 40 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.16118571 |
| 41 | ribosomal small subunit assembly (GO:0000028) | 3.14531971 |
| 42 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.13150599 |
| 43 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.12859663 |
| 44 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.12859663 |
| 45 | NADH dehydrogenase complex assembly (GO:0010257) | 3.12859663 |
| 46 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.12040743 |
| 47 | kynurenine metabolic process (GO:0070189) | 3.10884995 |
| 48 | positive regulation of defense response to virus by host (GO:0002230) | 3.05405674 |
| 49 | response to pheromone (GO:0019236) | 3.02806073 |
| 50 | mannosylation (GO:0097502) | 3.01826293 |
| 51 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.99887885 |
| 52 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.99436547 |
| 53 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.99436547 |
| 54 | iron-sulfur cluster assembly (GO:0016226) | 2.95538029 |
| 55 | metallo-sulfur cluster assembly (GO:0031163) | 2.95538029 |
| 56 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.93203203 |
| 57 | DNA demethylation (GO:0080111) | 2.91412014 |
| 58 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 2.90030570 |
| 59 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.87560971 |
| 60 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.87316696 |
| 61 | termination of RNA polymerase III transcription (GO:0006386) | 2.86996868 |
| 62 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.86996868 |
| 63 | rRNA methylation (GO:0031167) | 2.82807646 |
| 64 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.81466823 |
| 65 | positive regulation of protein homodimerization activity (GO:0090073) | 2.81138175 |
| 66 | indole-containing compound catabolic process (GO:0042436) | 2.80476730 |
| 67 | indolalkylamine catabolic process (GO:0046218) | 2.80476730 |
| 68 | tryptophan catabolic process (GO:0006569) | 2.80476730 |
| 69 | GPI anchor biosynthetic process (GO:0006506) | 2.80025293 |
| 70 | protein deneddylation (GO:0000338) | 2.77776193 |
| 71 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 2.77095691 |
| 72 | L-methionine salvage (GO:0071267) | 2.75776816 |
| 73 | L-methionine biosynthetic process (GO:0071265) | 2.75776816 |
| 74 | amino acid salvage (GO:0043102) | 2.75776816 |
| 75 | negative regulation by host of viral transcription (GO:0043922) | 2.74985580 |
| 76 | GPI anchor metabolic process (GO:0006505) | 2.74177209 |
| 77 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 2.73669242 |
| 78 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.72731995 |
| 79 | positive regulation of ligase activity (GO:0051351) | 2.72160550 |
| 80 | pseudouridine synthesis (GO:0001522) | 2.71703705 |
| 81 | regulation of cellular amine metabolic process (GO:0033238) | 2.67680948 |
| 82 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.66067466 |
| 83 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.66067466 |
| 84 | isotype switching (GO:0045190) | 2.66067466 |
| 85 | positive regulation of cell cycle arrest (GO:0071158) | 2.63305326 |
| 86 | cullin deneddylation (GO:0010388) | 2.60612605 |
| 87 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.58809740 |
| 88 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 2.58287673 |
| 89 | S-adenosylmethionine metabolic process (GO:0046500) | 2.58184954 |
| 90 | hydrogen ion transmembrane transport (GO:1902600) | 2.54814685 |
| 91 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.53111892 |
| 92 | DNA dealkylation (GO:0035510) | 2.52982856 |
| 93 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.50827926 |
| 94 | proton transport (GO:0015992) | 2.49897425 |
| 95 | positive regulation of interleukin-17 production (GO:0032740) | 2.48109821 |
| 96 | hydrogen transport (GO:0006818) | 2.47340254 |
| 97 | cellular response to interleukin-15 (GO:0071350) | 2.47079646 |
| 98 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.46837208 |
| 99 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.46837208 |
| 100 | response to interferon-beta (GO:0035456) | 2.46498502 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.35230672 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.95808618 |
| 3 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.95462158 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.34085342 |
| 5 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.95519354 |
| 6 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.93716769 |
| 7 | VDR_22108803_ChIP-Seq_LS180_Human | 2.86655843 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.85014381 |
| 9 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.80292178 |
| 10 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.73876366 |
| 11 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.58445287 |
| 12 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.56800643 |
| 13 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.43317948 |
| 14 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.40524018 |
| 15 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.38639452 |
| 16 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.30044425 |
| 17 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.22266957 |
| 18 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.15702007 |
| 19 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.13378483 |
| 20 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.12657695 |
| 21 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.04894309 |
| 22 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.00009027 |
| 23 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.98402468 |
| 24 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.95598995 |
| 25 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.93459401 |
| 26 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.86174617 |
| 27 | EWS_26573619_Chip-Seq_HEK293_Human | 1.84764242 |
| 28 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.78086093 |
| 29 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.71196513 |
| 30 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.69094157 |
| 31 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.67988226 |
| 32 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.62247901 |
| 33 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.61056259 |
| 34 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.59942753 |
| 35 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.57854898 |
| 36 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.56969985 |
| 37 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.54540960 |
| 38 | FUS_26573619_Chip-Seq_HEK293_Human | 1.50964738 |
| 39 | GATA3_26560356_Chip-Seq_TH2_Human | 1.48947490 |
| 40 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.46588575 |
| 41 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.44293771 |
| 42 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.44293771 |
| 43 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.42842976 |
| 44 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.42284863 |
| 45 | MYB_26560356_Chip-Seq_TH2_Human | 1.41361985 |
| 46 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.39239607 |
| 47 | AR_20517297_ChIP-Seq_VCAP_Human | 1.36469268 |
| 48 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.36312646 |
| 49 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.32476045 |
| 50 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.32125799 |
| 51 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.31927539 |
| 52 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.31826560 |
| 53 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.31522218 |
| 54 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.26289235 |
| 55 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.23748668 |
| 56 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.23748668 |
| 57 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.23530923 |
| 58 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.22362771 |
| 59 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.22332955 |
| 60 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.22174448 |
| 61 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.21807718 |
| 62 | P300_19829295_ChIP-Seq_ESCs_Human | 1.19590883 |
| 63 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.19389986 |
| 64 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.18372674 |
| 65 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.14374237 |
| 66 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.13879583 |
| 67 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.13563719 |
| 68 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.13543640 |
| 69 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.12649542 |
| 70 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.12558235 |
| 71 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.11713227 |
| 72 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.11545464 |
| 73 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.10249647 |
| 74 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.09132252 |
| 75 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.09125017 |
| 76 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.08811946 |
| 77 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.08636782 |
| 78 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.06379140 |
| 79 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.06379140 |
| 80 | NCOR_22424771_ChIP-Seq_293T_Human | 1.05827991 |
| 81 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.05049756 |
| 82 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.04993374 |
| 83 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.03994954 |
| 84 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.03917173 |
| 85 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.03587496 |
| 86 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.03471193 |
| 87 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.03379352 |
| 88 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.03219970 |
| 89 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.02554046 |
| 90 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.01271803 |
| 91 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.99978207 |
| 92 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.99466014 |
| 93 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.98039761 |
| 94 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.97823865 |
| 95 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.96472722 |
| 96 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.96460767 |
| 97 | GATA3_26560356_Chip-Seq_TH1_Human | 0.95766126 |
| 98 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.95420667 |
| 99 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.94716813 |
| 100 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.94502167 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 3.99633640 |
| 2 | MP0001835_abnormal_antigen_presentation | 3.75981884 |
| 3 | MP0002102_abnormal_ear_morphology | 2.65134878 |
| 4 | MP0006072_abnormal_retinal_apoptosis | 2.45870550 |
| 5 | MP0009785_altered_susceptibility_to | 2.44914678 |
| 6 | MP0000372_irregular_coat_pigmentation | 2.27113806 |
| 7 | MP0003786_premature_aging | 2.18113915 |
| 8 | MP0006292_abnormal_olfactory_placode | 2.13579367 |
| 9 | MP0005084_abnormal_gallbladder_morpholo | 2.12371026 |
| 10 | MP0004147_increased_porphyrin_level | 2.06140620 |
| 11 | MP0002166_altered_tumor_susceptibility | 1.97554302 |
| 12 | MP0008877_abnormal_DNA_methylation | 1.97428090 |
| 13 | MP0001800_abnormal_humoral_immune | 1.95503679 |
| 14 | MP0002837_dystrophic_cardiac_calcinosis | 1.92254357 |
| 15 | MP0002148_abnormal_hypersensitivity_rea | 1.91790798 |
| 16 | MP0006036_abnormal_mitochondrial_physio | 1.88618022 |
| 17 | MP0003806_abnormal_nucleotide_metabolis | 1.88315981 |
| 18 | MP0003195_calcinosis | 1.85804987 |
| 19 | MP0009333_abnormal_splenocyte_physiolog | 1.82859777 |
| 20 | MP0008872_abnormal_physiological_respon | 1.81400098 |
| 21 | MP0002876_abnormal_thyroid_physiology | 1.80343028 |
| 22 | MP0005075_abnormal_melanosome_morpholog | 1.71740835 |
| 23 | MP0002006_tumorigenesis | 1.68709193 |
| 24 | MP0005646_abnormal_pituitary_gland | 1.66909623 |
| 25 | MP0001986_abnormal_taste_sensitivity | 1.66836096 |
| 26 | MP0005000_abnormal_immune_tolerance | 1.65672633 |
| 27 | MP0001873_stomach_inflammation | 1.55774058 |
| 28 | MP0003763_abnormal_thymus_physiology | 1.55434191 |
| 29 | MP0005253_abnormal_eye_physiology | 1.55281158 |
| 30 | MP0002723_abnormal_immune_serum | 1.53582190 |
| 31 | MP0008058_abnormal_DNA_repair | 1.52257883 |
| 32 | MP0008875_abnormal_xenobiotic_pharmacok | 1.51653140 |
| 33 | MP0004145_abnormal_muscle_electrophysio | 1.50017913 |
| 34 | MP0005645_abnormal_hypothalamus_physiol | 1.47661569 |
| 35 | MP0005551_abnormal_eye_electrophysiolog | 1.47489435 |
| 36 | MP0000685_abnormal_immune_system | 1.46366722 |
| 37 | MP0002452_abnormal_antigen_presenting | 1.43817739 |
| 38 | MP0008995_early_reproductive_senescence | 1.43629731 |
| 39 | MP0003718_maternal_effect | 1.43488191 |
| 40 | MP0002420_abnormal_adaptive_immunity | 1.42763364 |
| 41 | MP0003011_delayed_dark_adaptation | 1.42726969 |
| 42 | MP0001819_abnormal_immune_cell | 1.42162523 |
| 43 | MP0005387_immune_system_phenotype | 1.39493643 |
| 44 | MP0001790_abnormal_immune_system | 1.39493643 |
| 45 | MP0002163_abnormal_gland_morphology | 1.36835375 |
| 46 | MP0009697_abnormal_copulation | 1.30362219 |
| 47 | MP0003646_muscle_fatigue | 1.29975180 |
| 48 | MP0003866_abnormal_defecation | 1.28876355 |
| 49 | MP0001764_abnormal_homeostasis | 1.28551247 |
| 50 | MP0001919_abnormal_reproductive_system | 1.28221086 |
| 51 | MP0003724_increased_susceptibility_to | 1.27475118 |
| 52 | MP0005025_abnormal_response_to | 1.27466291 |
| 53 | MP0001968_abnormal_touch/_nociception | 1.27008160 |
| 54 | MP0005389_reproductive_system_phenotype | 1.22483767 |
| 55 | MP0006082_CNS_inflammation | 1.22378377 |
| 56 | MP0002736_abnormal_nociception_after | 1.17115299 |
| 57 | MP0006035_abnormal_mitochondrial_morpho | 1.16377942 |
| 58 | MP0009764_decreased_sensitivity_to | 1.12951647 |
| 59 | MP0002398_abnormal_bone_marrow | 1.11522872 |
| 60 | MP0010155_abnormal_intestine_physiology | 1.10960516 |
| 61 | MP0000716_abnormal_immune_system | 1.10411054 |
| 62 | MP0002138_abnormal_hepatobiliary_system | 1.08363991 |
| 63 | MP0001905_abnormal_dopamine_level | 1.08150870 |
| 64 | MP0000689_abnormal_spleen_morphology | 1.07904737 |
| 65 | MP0003252_abnormal_bile_duct | 1.02665710 |
| 66 | MP0010094_abnormal_chromosome_stability | 1.02625033 |
| 67 | MP0001845_abnormal_inflammatory_respons | 1.02128717 |
| 68 | MP0005379_endocrine/exocrine_gland_phen | 1.00908127 |
| 69 | MP0008007_abnormal_cellular_replicative | 0.99854329 |
| 70 | MP0003880_abnormal_central_pattern | 0.95481699 |
| 71 | MP0006276_abnormal_autonomic_nervous | 0.93393619 |
| 72 | MP0002095_abnormal_skin_pigmentation | 0.91523723 |
| 73 | MP0003186_abnormal_redox_activity | 0.91344840 |
| 74 | MP0002722_abnormal_immune_system | 0.90999673 |
| 75 | MP0002429_abnormal_blood_cell | 0.89651203 |
| 76 | MP0002693_abnormal_pancreas_physiology | 0.88479891 |
| 77 | MP0001529_abnormal_vocalization | 0.88404372 |
| 78 | MP0000465_gastrointestinal_hemorrhage | 0.87043521 |
| 79 | MP0005332_abnormal_amino_acid | 0.86912221 |
| 80 | MP0001661_extended_life_span | 0.86908799 |
| 81 | MP0005410_abnormal_fertilization | 0.84169390 |
| 82 | MP0002405_respiratory_system_inflammati | 0.83814101 |
| 83 | MP0008469_abnormal_protein_level | 0.83773402 |
| 84 | MP0004142_abnormal_muscle_tone | 0.83076622 |
| 85 | MP0000703_abnormal_thymus_morphology | 0.82292083 |
| 86 | MP0005636_abnormal_mineral_homeostasis | 0.81354252 |
| 87 | MP0001853_heart_inflammation | 0.80335241 |
| 88 | MP0002234_abnormal_pharynx_morphology | 0.80259248 |
| 89 | MP0003567_abnormal_fetal_cardiomyocyte | 0.79880013 |
| 90 | MP0002419_abnormal_innate_immunity | 0.76365534 |
| 91 | MP0003787_abnormal_imprinting | 0.76181285 |
| 92 | MP0001293_anophthalmia | 0.76075632 |
| 93 | MP0005085_abnormal_gallbladder_physiolo | 0.75777526 |
| 94 | MP0002090_abnormal_vision | 0.75463124 |
| 95 | MP0001119_abnormal_female_reproductive | 0.74838749 |
| 96 | MP0002019_abnormal_tumor_incidence | 0.73835996 |
| 97 | MP0004215_abnormal_myocardial_fiber | 0.72719767 |
| 98 | MP0010386_abnormal_urinary_bladder | 0.70934689 |
| 99 | MP0002160_abnormal_reproductive_system | 0.69311029 |
| 100 | MP0009763_increased_sensitivity_to | 0.68065088 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Mitochondrial inheritance (HP:0001427) | 4.19459162 |
| 2 | Increased CSF lactate (HP:0002490) | 4.00818260 |
| 3 | Acute necrotizing encephalopathy (HP:0006965) | 3.96516546 |
| 4 | Hepatocellular necrosis (HP:0001404) | 3.90877995 |
| 5 | IgG deficiency (HP:0004315) | 3.70347675 |
| 6 | Stomatitis (HP:0010280) | 3.68749905 |
| 7 | Increased hepatocellular lipid droplets (HP:0006565) | 3.61120818 |
| 8 | Hepatic necrosis (HP:0002605) | 3.57833704 |
| 9 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.56682299 |
| 10 | Lipid accumulation in hepatocytes (HP:0006561) | 3.42855755 |
| 11 | Progressive macrocephaly (HP:0004481) | 3.40007480 |
| 12 | Severe combined immunodeficiency (HP:0004430) | 3.38759331 |
| 13 | Acute encephalopathy (HP:0006846) | 3.28425575 |
| 14 | Hypoproteinemia (HP:0003075) | 3.25989109 |
| 15 | T lymphocytopenia (HP:0005403) | 3.22703082 |
| 16 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.21501294 |
| 17 | Abnormality of the prostate (HP:0008775) | 3.14649574 |
| 18 | Abnormality of T cell number (HP:0011839) | 3.08451890 |
| 19 | Aplastic anemia (HP:0001915) | 3.08347700 |
| 20 | Abnormality of B cell number (HP:0010975) | 3.06292367 |
| 21 | Renal Fanconi syndrome (HP:0001994) | 3.01200009 |
| 22 | Increased serum lactate (HP:0002151) | 2.97445885 |
| 23 | Thyroiditis (HP:0100646) | 2.94987224 |
| 24 | B lymphocytopenia (HP:0010976) | 2.91622840 |
| 25 | Congenital stationary night blindness (HP:0007642) | 2.88785069 |
| 26 | 3-Methylglutaconic aciduria (HP:0003535) | 2.84997713 |
| 27 | Methylmalonic acidemia (HP:0002912) | 2.81869701 |
| 28 | Pancreatic cysts (HP:0001737) | 2.80381766 |
| 29 | Increased intramyocellular lipid droplets (HP:0012240) | 2.78617266 |
| 30 | Cerebral edema (HP:0002181) | 2.75367735 |
| 31 | Congenital, generalized hypertrichosis (HP:0004540) | 2.71957040 |
| 32 | Abolished electroretinogram (ERG) (HP:0000550) | 2.69335119 |
| 33 | Combined immunodeficiency (HP:0005387) | 2.58622004 |
| 34 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.57685440 |
| 35 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.57685440 |
| 36 | Abnormality of alanine metabolism (HP:0010916) | 2.54615159 |
| 37 | Hyperalaninemia (HP:0003348) | 2.54615159 |
| 38 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.54615159 |
| 39 | Lactic acidosis (HP:0003128) | 2.54052969 |
| 40 | Abnormality of midbrain morphology (HP:0002418) | 2.50117754 |
| 41 | Molar tooth sign on MRI (HP:0002419) | 2.50117754 |
| 42 | Abnormality of T cells (HP:0002843) | 2.49960549 |
| 43 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.48263893 |
| 44 | Panhypogammaglobulinemia (HP:0003139) | 2.44604585 |
| 45 | Optic disc pallor (HP:0000543) | 2.39379481 |
| 46 | Decreased central vision (HP:0007663) | 2.37958613 |
| 47 | Exertional dyspnea (HP:0002875) | 2.37313048 |
| 48 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.36349405 |
| 49 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.36061356 |
| 50 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.35355876 |
| 51 | Increased muscle lipid content (HP:0009058) | 2.33281570 |
| 52 | Methylmalonic aciduria (HP:0012120) | 2.29967082 |
| 53 | Type 2 muscle fiber atrophy (HP:0003554) | 2.26174658 |
| 54 | True hermaphroditism (HP:0010459) | 2.22032714 |
| 55 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.21300553 |
| 56 | Abnormality of eosinophils (HP:0001879) | 2.18739878 |
| 57 | Nephronophthisis (HP:0000090) | 2.18122446 |
| 58 | Respiratory failure (HP:0002878) | 2.17446105 |
| 59 | Lethargy (HP:0001254) | 2.17142935 |
| 60 | Type I transferrin isoform profile (HP:0003642) | 2.15533857 |
| 61 | CNS demyelination (HP:0007305) | 2.11698601 |
| 62 | Attenuation of retinal blood vessels (HP:0007843) | 2.11401497 |
| 63 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.07693258 |
| 64 | Pancreatic fibrosis (HP:0100732) | 2.07642665 |
| 65 | Pancytopenia (HP:0001876) | 2.03979833 |
| 66 | Constricted visual fields (HP:0001133) | 2.02810120 |
| 67 | Prostate neoplasm (HP:0100787) | 2.00220546 |
| 68 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.98766269 |
| 69 | Recurrent bronchitis (HP:0002837) | 1.95588064 |
| 70 | Short tibia (HP:0005736) | 1.94724105 |
| 71 | Exercise intolerance (HP:0003546) | 1.94202298 |
| 72 | Hypothermia (HP:0002045) | 1.91469508 |
| 73 | Eosinophilia (HP:0001880) | 1.91087367 |
| 74 | IgM deficiency (HP:0002850) | 1.90800051 |
| 75 | Oral leukoplakia (HP:0002745) | 1.86304910 |
| 76 | Dicarboxylic aciduria (HP:0003215) | 1.85672956 |
| 77 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.85672956 |
| 78 | Agammaglobulinemia (HP:0004432) | 1.84987634 |
| 79 | Abnormality of serum amino acid levels (HP:0003112) | 1.84161728 |
| 80 | Glycosuria (HP:0003076) | 1.84149500 |
| 81 | Abnormality of urine glucose concentration (HP:0011016) | 1.84149500 |
| 82 | Autoimmune hemolytic anemia (HP:0001890) | 1.83042968 |
| 83 | Abnormality of male internal genitalia (HP:0000022) | 1.81954939 |
| 84 | Chronic sinusitis (HP:0011109) | 1.81796786 |
| 85 | Muscle fiber atrophy (HP:0100295) | 1.80300105 |
| 86 | Abnormality of macular pigmentation (HP:0008002) | 1.78281549 |
| 87 | Palpitations (HP:0001962) | 1.76611540 |
| 88 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.76544305 |
| 89 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.76544305 |
| 90 | Abnormal protein glycosylation (HP:0012346) | 1.76544305 |
| 91 | Abnormal glycosylation (HP:0012345) | 1.76544305 |
| 92 | Abnormality of renal resorption (HP:0011038) | 1.75961991 |
| 93 | Medial flaring of the eyebrow (HP:0010747) | 1.75845640 |
| 94 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.75744278 |
| 95 | Colon cancer (HP:0003003) | 1.75728500 |
| 96 | Supernumerary spleens (HP:0009799) | 1.75668430 |
| 97 | Leukodystrophy (HP:0002415) | 1.75006073 |
| 98 | Abnormality of the renal medulla (HP:0100957) | 1.74606373 |
| 99 | Progressive microcephaly (HP:0000253) | 1.71395284 |
| 100 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.70057083 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 4.14427388 |
| 2 | MAP4K2 | 3.41131887 |
| 3 | EIF2AK3 | 3.33074341 |
| 4 | VRK2 | 2.77506241 |
| 5 | ZAK | 2.75106099 |
| 6 | NUAK1 | 2.64787225 |
| 7 | TESK2 | 2.46208805 |
| 8 | MST4 | 2.38927115 |
| 9 | STK16 | 2.28281655 |
| 10 | KDR | 2.26033339 |
| 11 | GRK1 | 2.16504439 |
| 12 | BCKDK | 2.13436516 |
| 13 | TAOK3 | 2.01686062 |
| 14 | TLK1 | 2.00351602 |
| 15 | CDK19 | 1.92480117 |
| 16 | FRK | 1.89163595 |
| 17 | ADRBK2 | 1.79495566 |
| 18 | EIF2AK1 | 1.79393730 |
| 19 | BMPR2 | 1.67211270 |
| 20 | ITK | 1.52271492 |
| 21 | VRK1 | 1.45136492 |
| 22 | TEC | 1.42327250 |
| 23 | BUB1 | 1.40341880 |
| 24 | ERBB3 | 1.37646773 |
| 25 | BMPR1B | 1.28458314 |
| 26 | TRIM28 | 1.28364877 |
| 27 | PLK4 | 1.26246361 |
| 28 | MAP4K1 | 1.22137844 |
| 29 | SRPK1 | 1.12475378 |
| 30 | PINK1 | 1.11805429 |
| 31 | OXSR1 | 1.11675332 |
| 32 | SCYL2 | 1.11228527 |
| 33 | WNK3 | 1.10520644 |
| 34 | MKNK1 | 1.07109326 |
| 35 | DAPK1 | 1.06159864 |
| 36 | EIF2AK2 | 1.05362023 |
| 37 | MAP3K12 | 1.04549190 |
| 38 | PLK3 | 1.03405209 |
| 39 | INSRR | 1.02876432 |
| 40 | CSNK1G1 | 1.01724871 |
| 41 | KIT | 0.99819456 |
| 42 | IKBKB | 0.99502996 |
| 43 | FES | 0.98671433 |
| 44 | PBK | 0.96929724 |
| 45 | SYK | 0.93556107 |
| 46 | CSNK1G3 | 0.90997004 |
| 47 | CSF1R | 0.87653755 |
| 48 | NME1 | 0.86584175 |
| 49 | PLK2 | 0.82911060 |
| 50 | WNK4 | 0.82634224 |
| 51 | PIK3CG | 0.82197668 |
| 52 | MKNK2 | 0.76326051 |
| 53 | BTK | 0.74613567 |
| 54 | MYLK | 0.74248233 |
| 55 | TSSK6 | 0.71974323 |
| 56 | CSNK1G2 | 0.71326822 |
| 57 | FLT3 | 0.71291056 |
| 58 | RPS6KA5 | 0.70897161 |
| 59 | MUSK | 0.69695640 |
| 60 | IKBKE | 0.69633633 |
| 61 | RPS6KA4 | 0.69369878 |
| 62 | PRKCQ | 0.69176364 |
| 63 | DAPK2 | 0.66911049 |
| 64 | LYN | 0.66786308 |
| 65 | LCK | 0.66742671 |
| 66 | CSNK1A1L | 0.65491942 |
| 67 | NLK | 0.65419719 |
| 68 | GRK6 | 0.64374355 |
| 69 | MAPKAPK3 | 0.62994367 |
| 70 | TIE1 | 0.61045111 |
| 71 | MATK | 0.57392530 |
| 72 | NEK1 | 0.57122565 |
| 73 | PHKG1 | 0.56678160 |
| 74 | PHKG2 | 0.56678160 |
| 75 | STK39 | 0.54766858 |
| 76 | ATR | 0.52906896 |
| 77 | PRKCE | 0.51413800 |
| 78 | OBSCN | 0.49545549 |
| 79 | AURKB | 0.49218476 |
| 80 | CDK3 | 0.48307363 |
| 81 | CDC7 | 0.48028180 |
| 82 | STK38L | 0.47442607 |
| 83 | TAF1 | 0.46552221 |
| 84 | TNK2 | 0.45461365 |
| 85 | GRK7 | 0.44538285 |
| 86 | IGF1R | 0.43792694 |
| 87 | PLK1 | 0.43431803 |
| 88 | GRK5 | 0.43312182 |
| 89 | TRPM7 | 0.43160002 |
| 90 | BCR | 0.41264683 |
| 91 | CSNK2A1 | 0.41086802 |
| 92 | LIMK1 | 0.38839235 |
| 93 | PASK | 0.38643337 |
| 94 | TBK1 | 0.38212375 |
| 95 | MAPKAPK5 | 0.38212049 |
| 96 | CDK8 | 0.38204089 |
| 97 | HCK | 0.38194734 |
| 98 | MAPK13 | 0.36937465 |
| 99 | JAK3 | 0.36813337 |
| 100 | PIK3CA | 0.35542971 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.55271345 |
| 2 | Asthma_Homo sapiens_hsa05310 | 3.41559971 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.13694295 |
| 4 | Allograft rejection_Homo sapiens_hsa05330 | 3.08978778 |
| 5 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.00365500 |
| 6 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.79469044 |
| 7 | Protein export_Homo sapiens_hsa03060 | 2.79042432 |
| 8 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.79001931 |
| 9 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.70244015 |
| 10 | Parkinsons disease_Homo sapiens_hsa05012 | 2.62981854 |
| 11 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.57353698 |
| 12 | RNA polymerase_Homo sapiens_hsa03020 | 2.09438499 |
| 13 | Homologous recombination_Homo sapiens_hsa03440 | 1.97729232 |
| 14 | Ribosome_Homo sapiens_hsa03010 | 1.93849692 |
| 15 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.91505811 |
| 16 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.89018353 |
| 17 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.67093749 |
| 18 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.67000753 |
| 19 | Alzheimers disease_Homo sapiens_hsa05010 | 1.56765974 |
| 20 | Huntingtons disease_Homo sapiens_hsa05016 | 1.55770789 |
| 21 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.54401438 |
| 22 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.54076912 |
| 23 | RNA degradation_Homo sapiens_hsa03018 | 1.52325102 |
| 24 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.43985661 |
| 25 | Mismatch repair_Homo sapiens_hsa03430 | 1.38927310 |
| 26 | Phototransduction_Homo sapiens_hsa04744 | 1.35472046 |
| 27 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.32692222 |
| 28 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.29392353 |
| 29 | DNA replication_Homo sapiens_hsa03030 | 1.27824855 |
| 30 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.22793510 |
| 31 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.20799500 |
| 32 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.14499761 |
| 33 | Spliceosome_Homo sapiens_hsa03040 | 1.10761494 |
| 34 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.09885500 |
| 35 | Basal transcription factors_Homo sapiens_hsa03022 | 1.08768463 |
| 36 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.08213731 |
| 37 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.06576779 |
| 38 | RNA transport_Homo sapiens_hsa03013 | 1.00892168 |
| 39 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.00136788 |
| 40 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.95282893 |
| 41 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.95262463 |
| 42 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.94740149 |
| 43 | Peroxisome_Homo sapiens_hsa04146 | 0.94123723 |
| 44 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.92863008 |
| 45 | Purine metabolism_Homo sapiens_hsa00230 | 0.92681343 |
| 46 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.91196584 |
| 47 | Viral myocarditis_Homo sapiens_hsa05416 | 0.90061292 |
| 48 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.89619902 |
| 49 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.89068886 |
| 50 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.88132797 |
| 51 | Base excision repair_Homo sapiens_hsa03410 | 0.82726824 |
| 52 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.77320315 |
| 53 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.77205727 |
| 54 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.73444915 |
| 55 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.71899756 |
| 56 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.71523724 |
| 57 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.69941105 |
| 58 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.67029035 |
| 59 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.66993978 |
| 60 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.65713458 |
| 61 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.64942451 |
| 62 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.63511520 |
| 63 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.63322394 |
| 64 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.62949266 |
| 65 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.61855940 |
| 66 | Olfactory transduction_Homo sapiens_hsa04740 | 0.59858472 |
| 67 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.58557496 |
| 68 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.57998275 |
| 69 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.57187686 |
| 70 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.57048599 |
| 71 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.56001414 |
| 72 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.55532731 |
| 73 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.53942932 |
| 74 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.53363196 |
| 75 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.53272531 |
| 76 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.52673475 |
| 77 | Metabolic pathways_Homo sapiens_hsa01100 | 0.52386086 |
| 78 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.50687319 |
| 79 | Retinol metabolism_Homo sapiens_hsa00830 | 0.49707403 |
| 80 | Leishmaniasis_Homo sapiens_hsa05140 | 0.49609424 |
| 81 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.49507070 |
| 82 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.49298303 |
| 83 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.48402923 |
| 84 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.45229082 |
| 85 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.45000141 |
| 86 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.44399113 |
| 87 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.43660200 |
| 88 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.42985932 |
| 89 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.41923290 |
| 90 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.41272233 |
| 91 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.40527759 |
| 92 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.39689987 |
| 93 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.35829994 |
| 94 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.35525303 |
| 95 | Measles_Homo sapiens_hsa05162 | 0.32944720 |
| 96 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.31809495 |
| 97 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.28850862 |
| 98 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.28797110 |
| 99 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.25883807 |
| 100 | Taste transduction_Homo sapiens_hsa04742 | 0.21113656 |

