

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | proteasome assembly (GO:0043248) | 5.58473741 |
| 2 | rRNA methylation (GO:0031167) | 5.43303736 |
| 3 | rRNA modification (GO:0000154) | 5.38358937 |
| 4 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 5.06689322 |
| 5 | ribosome assembly (GO:0042255) | 4.89651589 |
| 6 | maturation of 5.8S rRNA (GO:0000460) | 4.86739885 |
| 7 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 4.74917398 |
| 8 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.64003860 |
| 9 | DNA deamination (GO:0045006) | 4.51104033 |
| 10 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.46976056 |
| 11 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 4.20838103 |
| 12 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 4.18968215 |
| 13 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 4.07465083 |
| 14 | positive regulation of isotype switching (GO:0045830) | 3.99905443 |
| 15 | termination of RNA polymerase I transcription (GO:0006363) | 3.97423660 |
| 16 | DNA double-strand break processing (GO:0000729) | 3.97188381 |
| 17 | chaperone-mediated protein transport (GO:0072321) | 3.97127156 |
| 18 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.86259783 |
| 19 | cullin deneddylation (GO:0010388) | 3.80925000 |
| 20 | regulation of chronic inflammatory response (GO:0002676) | 3.78498726 |
| 21 | regulation of immunoglobulin secretion (GO:0051023) | 3.74545069 |
| 22 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.70761728 |
| 23 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.70409014 |
| 24 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.68855987 |
| 25 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.68855987 |
| 26 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.68855987 |
| 27 | positive regulation of DNA recombination (GO:0045911) | 3.65799443 |
| 28 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.64752208 |
| 29 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.64752208 |
| 30 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.62221985 |
| 31 | protein deneddylation (GO:0000338) | 3.61936799 |
| 32 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.59768216 |
| 33 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.58260860 |
| 34 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.54512431 |
| 35 | isotype switching (GO:0045190) | 3.54512431 |
| 36 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.54512431 |
| 37 | IMP biosynthetic process (GO:0006188) | 3.52737198 |
| 38 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.52499279 |
| 39 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.52499279 |
| 40 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.50169292 |
| 41 | termination of RNA polymerase III transcription (GO:0006386) | 3.50169292 |
| 42 | negative regulation of ligase activity (GO:0051352) | 3.48749479 |
| 43 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.48749479 |
| 44 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.48249272 |
| 45 | transcription initiation from RNA polymerase I promoter (GO:0006361) | 3.47545434 |
| 46 | rRNA processing (GO:0006364) | 3.44576451 |
| 47 | ribosome biogenesis (GO:0042254) | 3.41537563 |
| 48 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.36984397 |
| 49 | rRNA metabolic process (GO:0016072) | 3.36451075 |
| 50 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.34668182 |
| 51 | mitochondrial RNA metabolic process (GO:0000959) | 3.25123706 |
| 52 | pseudouridine synthesis (GO:0001522) | 3.24798404 |
| 53 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.21230782 |
| 54 | DNA damage response, detection of DNA damage (GO:0042769) | 3.19144900 |
| 55 | protein neddylation (GO:0045116) | 3.17047839 |
| 56 | transcription from RNA polymerase I promoter (GO:0006360) | 3.16886659 |
| 57 | chromatin remodeling at centromere (GO:0031055) | 3.14969556 |
| 58 | CENP-A containing nucleosome assembly (GO:0034080) | 3.14038332 |
| 59 | amino acid activation (GO:0043038) | 3.13165240 |
| 60 | tRNA aminoacylation (GO:0043039) | 3.13165240 |
| 61 | histone mRNA metabolic process (GO:0008334) | 3.12879542 |
| 62 | IMP metabolic process (GO:0046040) | 3.10502214 |
| 63 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.06931672 |
| 64 | tRNA aminoacylation for protein translation (GO:0006418) | 3.04820830 |
| 65 | transcription from mitochondrial promoter (GO:0006390) | 3.01403490 |
| 66 | GTP biosynthetic process (GO:0006183) | 2.98093838 |
| 67 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.97206543 |
| 68 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.97206543 |
| 69 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.93828136 |
| 70 | positive regulation of ligase activity (GO:0051351) | 2.91466510 |
| 71 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.90804677 |
| 72 | tRNA metabolic process (GO:0006399) | 2.88692862 |
| 73 | organelle disassembly (GO:1903008) | 2.87904696 |
| 74 | protein targeting to mitochondrion (GO:0006626) | 2.87128143 |
| 75 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 2.86776986 |
| 76 | positive regulation of B cell mediated immunity (GO:0002714) | 2.86776986 |
| 77 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.86404527 |
| 78 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.85734234 |
| 79 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.85734234 |
| 80 | regulation of regulatory T cell differentiation (GO:0045589) | 2.85399441 |
| 81 | ncRNA metabolic process (GO:0034660) | 2.83627144 |
| 82 | double-strand break repair via homologous recombination (GO:0000724) | 2.83227414 |
| 83 | telomere maintenance via telomerase (GO:0007004) | 2.81895138 |
| 84 | recombinational repair (GO:0000725) | 2.81538054 |
| 85 | positive regulation of cell cycle arrest (GO:0071158) | 2.80078983 |
| 86 | ncRNA processing (GO:0034470) | 2.79883893 |
| 87 | tRNA processing (GO:0008033) | 2.79627285 |
| 88 | spliceosomal snRNP assembly (GO:0000387) | 2.79067704 |
| 89 | intracellular protein transmembrane import (GO:0044743) | 2.78867616 |
| 90 | regulation of helicase activity (GO:0051095) | 2.77192821 |
| 91 | regulation of podosome assembly (GO:0071801) | 2.76790324 |
| 92 | DNA replication checkpoint (GO:0000076) | 2.75316261 |
| 93 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.74142884 |
| 94 | ribosomal large subunit biogenesis (GO:0042273) | 2.73683291 |
| 95 | DNA-templated transcription, termination (GO:0006353) | 2.73581151 |
| 96 | somatic recombination of immunoglobulin gene segments (GO:0016447) | 2.72293915 |
| 97 | histone exchange (GO:0043486) | 2.71376298 |
| 98 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.69783386 |
| 99 | peptidyl-histidine modification (GO:0018202) | 2.68588412 |
| 100 | folic acid-containing compound biosynthetic process (GO:0009396) | 2.67819843 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.67111966 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.18490034 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.68685817 |
| 4 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.02786813 |
| 5 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.90011666 |
| 6 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.85662394 |
| 7 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.71956285 |
| 8 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.69885220 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.66940739 |
| 10 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.47545555 |
| 11 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.46967499 |
| 12 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.46432464 |
| 13 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.36053645 |
| 14 | VDR_22108803_ChIP-Seq_LS180_Human | 2.29301315 |
| 15 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.25880445 |
| 16 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.22313169 |
| 17 | EWS_26573619_Chip-Seq_HEK293_Human | 2.22087267 |
| 18 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.19868723 |
| 19 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.12227368 |
| 20 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.11960272 |
| 21 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 2.09956700 |
| 22 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.05093800 |
| 23 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.99380783 |
| 24 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.92613217 |
| 25 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.91500701 |
| 26 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.90905343 |
| 27 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.88658188 |
| 28 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.84806896 |
| 29 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.83136537 |
| 30 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.81111642 |
| 31 | FUS_26573619_Chip-Seq_HEK293_Human | 1.75787628 |
| 32 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.74841098 |
| 33 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.63851769 |
| 34 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.60965594 |
| 35 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.56217054 |
| 36 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.55753730 |
| 37 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.55744543 |
| 38 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.54114051 |
| 39 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.53207150 |
| 40 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.51408330 |
| 41 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.49735161 |
| 42 | P300_19829295_ChIP-Seq_ESCs_Human | 1.49490791 |
| 43 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.49020396 |
| 44 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.45045682 |
| 45 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.41557469 |
| 46 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.40486605 |
| 47 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.40040861 |
| 48 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.39504413 |
| 49 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.36043027 |
| 50 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.33668909 |
| 51 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.33456894 |
| 52 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.28663629 |
| 53 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.26573670 |
| 54 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.25304856 |
| 55 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.23399127 |
| 56 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.23206720 |
| 57 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.19708215 |
| 58 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.19193143 |
| 59 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.18651974 |
| 60 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.15323639 |
| 61 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.15070837 |
| 62 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.13873353 |
| 63 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.13857377 |
| 64 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.12009903 |
| 65 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.06716209 |
| 66 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.05572881 |
| 67 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.05287405 |
| 68 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.05251409 |
| 69 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.05251409 |
| 70 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.03879732 |
| 71 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.03719084 |
| 72 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.03560946 |
| 73 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.02887897 |
| 74 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.01619225 |
| 75 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.01317061 |
| 76 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.01213384 |
| 77 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.00659581 |
| 78 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.00352287 |
| 79 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.99505242 |
| 80 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.98425484 |
| 81 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.98425484 |
| 82 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.97615772 |
| 83 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.96038982 |
| 84 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.95600076 |
| 85 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.95432876 |
| 86 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.95273336 |
| 87 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.94839430 |
| 88 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.94839430 |
| 89 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.94211946 |
| 90 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.93212723 |
| 91 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 0.93132572 |
| 92 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.92514187 |
| 93 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.92509090 |
| 94 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.92192512 |
| 95 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.90722408 |
| 96 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.89925254 |
| 97 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.89856712 |
| 98 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.89665159 |
| 99 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.89610817 |
| 100 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.89502987 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008057_abnormal_DNA_replication | 4.01283771 |
| 2 | MP0001835_abnormal_antigen_presentation | 3.42092809 |
| 3 | MP0008058_abnormal_DNA_repair | 3.36646041 |
| 4 | MP0008877_abnormal_DNA_methylation | 3.19542738 |
| 5 | MP0002102_abnormal_ear_morphology | 3.03115790 |
| 6 | MP0010094_abnormal_chromosome_stability | 2.66512537 |
| 7 | MP0000569_abnormal_digit_pigmentation | 2.62292287 |
| 8 | MP0004957_abnormal_blastocyst_morpholog | 2.55685302 |
| 9 | MP0003693_abnormal_embryo_hatching | 2.43366996 |
| 10 | MP0003786_premature_aging | 2.31034886 |
| 11 | MP0001984_abnormal_olfaction | 2.30555704 |
| 12 | MP0003718_maternal_effect | 2.10927132 |
| 13 | MP0003077_abnormal_cell_cycle | 2.08198064 |
| 14 | MP0002006_tumorigenesis | 2.04845275 |
| 15 | MP0009697_abnormal_copulation | 1.96567388 |
| 16 | MP0001853_heart_inflammation | 1.93780112 |
| 17 | MP0001873_stomach_inflammation | 1.80475637 |
| 18 | MP0003111_abnormal_nucleus_morphology | 1.77880275 |
| 19 | MP0008007_abnormal_cellular_replicative | 1.73603305 |
| 20 | MP0001529_abnormal_vocalization | 1.73284001 |
| 21 | MP0002166_altered_tumor_susceptibility | 1.73176380 |
| 22 | MP0003567_abnormal_fetal_cardiomyocyte | 1.72435690 |
| 23 | MP0006072_abnormal_retinal_apoptosis | 1.70185866 |
| 24 | MP0008872_abnormal_physiological_respon | 1.69797396 |
| 25 | MP0000685_abnormal_immune_system | 1.69245261 |
| 26 | MP0003195_calcinosis | 1.65026755 |
| 27 | MP0000372_irregular_coat_pigmentation | 1.64167366 |
| 28 | MP0006035_abnormal_mitochondrial_morpho | 1.63405237 |
| 29 | MP0006054_spinal_hemorrhage | 1.59514075 |
| 30 | MP0006036_abnormal_mitochondrial_physio | 1.57963223 |
| 31 | MP0003787_abnormal_imprinting | 1.50651476 |
| 32 | MP0003806_abnormal_nucleotide_metabolis | 1.48092580 |
| 33 | MP0004381_abnormal_hair_follicle | 1.47714788 |
| 34 | MP0005408_hypopigmentation | 1.47654896 |
| 35 | MP0000427_abnormal_hair_cycle | 1.40595503 |
| 36 | MP0006276_abnormal_autonomic_nervous | 1.35483066 |
| 37 | MP0005671_abnormal_response_to | 1.33488503 |
| 38 | MP0008875_abnormal_xenobiotic_pharmacok | 1.32166090 |
| 39 | MP0005645_abnormal_hypothalamus_physiol | 1.31880745 |
| 40 | MP0003186_abnormal_redox_activity | 1.31317645 |
| 41 | MP0009785_altered_susceptibility_to | 1.31103186 |
| 42 | MP0001881_abnormal_mammary_gland | 1.30841607 |
| 43 | MP0003011_delayed_dark_adaptation | 1.28129276 |
| 44 | MP0005075_abnormal_melanosome_morpholog | 1.27687795 |
| 45 | MP0003121_genomic_imprinting | 1.22594411 |
| 46 | MP0001293_anophthalmia | 1.22007948 |
| 47 | MP0003646_muscle_fatigue | 1.21368694 |
| 48 | MP0008932_abnormal_embryonic_tissue | 1.20298899 |
| 49 | MP0000604_amyloidosis | 1.17913623 |
| 50 | MP0005310_abnormal_salivary_gland | 1.15971226 |
| 51 | MP0002751_abnormal_autonomic_nervous | 1.12988720 |
| 52 | MP0002148_abnormal_hypersensitivity_rea | 1.10454210 |
| 53 | MP0005253_abnormal_eye_physiology | 1.09823502 |
| 54 | MP0002277_abnormal_respiratory_mucosa | 1.07729992 |
| 55 | MP0002138_abnormal_hepatobiliary_system | 1.02689521 |
| 56 | MP0001800_abnormal_humoral_immune | 1.01752536 |
| 57 | MP0003300_gastrointestinal_ulcer | 1.00238970 |
| 58 | MP0004142_abnormal_muscle_tone | 0.98904828 |
| 59 | MP0006292_abnormal_olfactory_placode | 0.98718673 |
| 60 | MP0010352_gastrointestinal_tract_polyps | 0.97413253 |
| 61 | MP0002938_white_spotting | 0.97025830 |
| 62 | MP0005387_immune_system_phenotype | 0.96639769 |
| 63 | MP0001790_abnormal_immune_system | 0.96639769 |
| 64 | MP0003122_maternal_imprinting | 0.96124297 |
| 65 | MP0002163_abnormal_gland_morphology | 0.92746025 |
| 66 | MP0001929_abnormal_gametogenesis | 0.92289811 |
| 67 | MP0001188_hyperpigmentation | 0.88012147 |
| 68 | MP0001119_abnormal_female_reproductive | 0.85214239 |
| 69 | MP0002405_respiratory_system_inflammati | 0.85180939 |
| 70 | MP0002210_abnormal_sex_determination | 0.85005604 |
| 71 | MP0008873_increased_physiological_sensi | 0.84333908 |
| 72 | MP0005266_abnormal_metabolism | 0.82001175 |
| 73 | MP0008995_early_reproductive_senescence | 0.81976807 |
| 74 | MP0003763_abnormal_thymus_physiology | 0.80462243 |
| 75 | MP0009765_abnormal_xenobiotic_induced | 0.78940483 |
| 76 | MP0005551_abnormal_eye_electrophysiolog | 0.78838869 |
| 77 | MP0002693_abnormal_pancreas_physiology | 0.76561600 |
| 78 | MP0000689_abnormal_spleen_morphology | 0.75415553 |
| 79 | MP0003866_abnormal_defecation | 0.75326875 |
| 80 | MP0001730_embryonic_growth_arrest | 0.75283259 |
| 81 | MP0005410_abnormal_fertilization | 0.74408096 |
| 82 | MP0009764_decreased_sensitivity_to | 0.74353783 |
| 83 | MP0010307_abnormal_tumor_latency | 0.74304548 |
| 84 | MP0003890_abnormal_embryonic-extraembry | 0.73788284 |
| 85 | MP0000653_abnormal_sex_gland | 0.73274031 |
| 86 | MP0002019_abnormal_tumor_incidence | 0.72570492 |
| 87 | MP0003937_abnormal_limbs/digits/tail_de | 0.69272957 |
| 88 | MP0003221_abnormal_cardiomyocyte_apopto | 0.68874120 |
| 89 | MP0010386_abnormal_urinary_bladder | 0.68715881 |
| 90 | MP0000465_gastrointestinal_hemorrhage | 0.68538778 |
| 91 | MP0001348_abnormal_lacrimal_gland | 0.66944073 |
| 92 | MP0002736_abnormal_nociception_after | 0.66789871 |
| 93 | MP0000631_abnormal_neuroendocrine_gland | 0.65942046 |
| 94 | MP0002396_abnormal_hematopoietic_system | 0.65460107 |
| 95 | MP0000703_abnormal_thymus_morphology | 0.65456356 |
| 96 | MP0009333_abnormal_splenocyte_physiolog | 0.63557375 |
| 97 | MP0005379_endocrine/exocrine_gland_phen | 0.63161915 |
| 98 | MP0003936_abnormal_reproductive_system | 0.62508419 |
| 99 | MP0001145_abnormal_male_reproductive | 0.62020386 |
| 100 | MP0004782_abnormal_surfactant_physiolog | 0.61996816 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Stomatitis (HP:0010280) | 4.29424205 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 4.08309445 |
| 3 | Acute encephalopathy (HP:0006846) | 3.65149259 |
| 4 | Progressive macrocephaly (HP:0004481) | 3.64543299 |
| 5 | Abnormality of the labia minora (HP:0012880) | 3.54992069 |
| 6 | Increased CSF lactate (HP:0002490) | 3.51463275 |
| 7 | Pancreatic cysts (HP:0001737) | 3.39308934 |
| 8 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.33125922 |
| 9 | Mitochondrial inheritance (HP:0001427) | 3.28832834 |
| 10 | Increased hepatocellular lipid droplets (HP:0006565) | 3.09474863 |
| 11 | Hypoplasia of the pons (HP:0012110) | 3.02644946 |
| 12 | IgG deficiency (HP:0004315) | 2.96078553 |
| 13 | Lipid accumulation in hepatocytes (HP:0006561) | 2.89322236 |
| 14 | Abnormality of the pons (HP:0007361) | 2.89162891 |
| 15 | Molar tooth sign on MRI (HP:0002419) | 2.83742196 |
| 16 | Abnormality of midbrain morphology (HP:0002418) | 2.83742196 |
| 17 | Colon cancer (HP:0003003) | 2.79192033 |
| 18 | Posterior subcapsular cataract (HP:0007787) | 2.74102426 |
| 19 | Increased serum lactate (HP:0002151) | 2.70034926 |
| 20 | 3-Methylglutaconic aciduria (HP:0003535) | 2.66240304 |
| 21 | Pancreatic fibrosis (HP:0100732) | 2.62704682 |
| 22 | Exertional dyspnea (HP:0002875) | 2.58352939 |
| 23 | Methylmalonic acidemia (HP:0002912) | 2.54912132 |
| 24 | Cerebral edema (HP:0002181) | 2.50278977 |
| 25 | Abnormality of alanine metabolism (HP:0010916) | 2.46401324 |
| 26 | Hyperalaninemia (HP:0003348) | 2.46401324 |
| 27 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.46401324 |
| 28 | Nephronophthisis (HP:0000090) | 2.39789733 |
| 29 | Amniotic constriction ring (HP:0009775) | 2.37094968 |
| 30 | Abnormality of placental membranes (HP:0011409) | 2.37094968 |
| 31 | Optic disc pallor (HP:0000543) | 2.35750454 |
| 32 | Hepatocellular necrosis (HP:0001404) | 2.32011318 |
| 33 | Leukodystrophy (HP:0002415) | 2.30395591 |
| 34 | Progressive inability to walk (HP:0002505) | 2.28631905 |
| 35 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.26581086 |
| 36 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.24787932 |
| 37 | Methylmalonic aciduria (HP:0012120) | 2.20186110 |
| 38 | Sensory axonal neuropathy (HP:0003390) | 2.19893534 |
| 39 | Degeneration of anterior horn cells (HP:0002398) | 2.18274354 |
| 40 | Abnormality of the anterior horn cell (HP:0006802) | 2.18274354 |
| 41 | Abnormality of chromosome stability (HP:0003220) | 2.15494087 |
| 42 | True hermaphroditism (HP:0010459) | 2.09529209 |
| 43 | Congenital, generalized hypertrichosis (HP:0004540) | 2.08828833 |
| 44 | Type II lissencephaly (HP:0007260) | 2.08797616 |
| 45 | Thyroiditis (HP:0100646) | 2.08656354 |
| 46 | Hepatic necrosis (HP:0002605) | 2.08084674 |
| 47 | IgA deficiency (HP:0002720) | 2.07649661 |
| 48 | Renal Fanconi syndrome (HP:0001994) | 2.07036083 |
| 49 | Abnormality of the renal medulla (HP:0100957) | 2.06672661 |
| 50 | Pelvic girdle muscle weakness (HP:0003749) | 2.04680113 |
| 51 | Prominent metopic ridge (HP:0005487) | 2.04216961 |
| 52 | Type 2 muscle fiber atrophy (HP:0003554) | 2.03941604 |
| 53 | Cerebral hemorrhage (HP:0001342) | 2.01269753 |
| 54 | Abnormality of serum amino acid levels (HP:0003112) | 2.00916083 |
| 55 | Abnormality of methionine metabolism (HP:0010901) | 2.00463963 |
| 56 | Meckel diverticulum (HP:0002245) | 2.00348046 |
| 57 | Pendular nystagmus (HP:0012043) | 1.98609464 |
| 58 | Respiratory failure (HP:0002878) | 1.96091450 |
| 59 | Supernumerary spleens (HP:0009799) | 1.95663364 |
| 60 | Oligodactyly (hands) (HP:0001180) | 1.95660711 |
| 61 | Abnormality of the ileum (HP:0001549) | 1.92752670 |
| 62 | Abnormality of the metopic suture (HP:0005556) | 1.91576974 |
| 63 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.90988988 |
| 64 | Volvulus (HP:0002580) | 1.90176976 |
| 65 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 1.89276652 |
| 66 | Hypoplasia of the fovea (HP:0007750) | 1.89276652 |
| 67 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.84442658 |
| 68 | Exercise intolerance (HP:0003546) | 1.84174223 |
| 69 | Lactic acidosis (HP:0003128) | 1.84013445 |
| 70 | Abnormality of the renal cortex (HP:0011035) | 1.83998936 |
| 71 | Neoplasm of the adrenal cortex (HP:0100641) | 1.83697951 |
| 72 | Gaze-evoked nystagmus (HP:0000640) | 1.82279259 |
| 73 | Hypoglycemic coma (HP:0001325) | 1.80364622 |
| 74 | Lethargy (HP:0001254) | 1.78659411 |
| 75 | T lymphocytopenia (HP:0005403) | 1.76642085 |
| 76 | Dandy-Walker malformation (HP:0001305) | 1.76048872 |
| 77 | Hypomagnesemia (HP:0002917) | 1.73314646 |
| 78 | Abolished electroretinogram (ERG) (HP:0000550) | 1.72998098 |
| 79 | Respiratory difficulties (HP:0002880) | 1.72982315 |
| 80 | Medial flaring of the eyebrow (HP:0010747) | 1.72002481 |
| 81 | Clubbing of toes (HP:0100760) | 1.71316736 |
| 82 | Abnormal hair whorl (HP:0010721) | 1.70201217 |
| 83 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.69762372 |
| 84 | Oral leukoplakia (HP:0002745) | 1.69698692 |
| 85 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.69434868 |
| 86 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.69434868 |
| 87 | Abnormality of T cell number (HP:0011839) | 1.69354635 |
| 88 | Increased IgM level (HP:0003496) | 1.68953319 |
| 89 | Adrenal hypoplasia (HP:0000835) | 1.67159039 |
| 90 | Horseshoe kidney (HP:0000085) | 1.66468847 |
| 91 | Abnormality of T cell physiology (HP:0011840) | 1.65201141 |
| 92 | Hypoglycemic seizures (HP:0002173) | 1.64559440 |
| 93 | Abnormality of vitamin B metabolism (HP:0004340) | 1.63479891 |
| 94 | Cellular immunodeficiency (HP:0005374) | 1.62213387 |
| 95 | Ependymoma (HP:0002888) | 1.62209935 |
| 96 | Abnormality of T cells (HP:0002843) | 1.61848448 |
| 97 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.61659936 |
| 98 | Aplasia/Hypoplasia of the macula (HP:0008059) | 1.61453073 |
| 99 | Abnormality of the preputium (HP:0100587) | 1.61414754 |
| 100 | Abnormality of the fovea (HP:0000493) | 1.61034148 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TSSK6 | 4.98481070 |
| 2 | MST4 | 4.28927020 |
| 3 | EIF2AK3 | 3.23824765 |
| 4 | EIF2AK1 | 3.15554333 |
| 5 | MKNK2 | 2.97451026 |
| 6 | TRIM28 | 2.91077515 |
| 7 | NUAK1 | 2.79352467 |
| 8 | FRK | 2.69130426 |
| 9 | SRPK1 | 2.39674838 |
| 10 | PLK3 | 2.37878062 |
| 11 | MKNK1 | 2.15683626 |
| 12 | ZAK | 2.13949691 |
| 13 | NEK1 | 2.13914236 |
| 14 | PBK | 1.96529408 |
| 15 | BUB1 | 1.95620928 |
| 16 | VRK2 | 1.85966745 |
| 17 | TNIK | 1.81277309 |
| 18 | NME1 | 1.76486949 |
| 19 | BMPR1B | 1.72809599 |
| 20 | EIF2AK2 | 1.70128798 |
| 21 | OXSR1 | 1.68583529 |
| 22 | TAOK3 | 1.65604572 |
| 23 | PLK2 | 1.63122068 |
| 24 | ALK | 1.58089119 |
| 25 | WNK3 | 1.57002883 |
| 26 | STK16 | 1.53841080 |
| 27 | TAF1 | 1.47976461 |
| 28 | STK39 | 1.29209136 |
| 29 | NLK | 1.24500166 |
| 30 | TEC | 1.22555538 |
| 31 | ACVR1B | 1.21146228 |
| 32 | VRK1 | 1.20141583 |
| 33 | PLK4 | 1.17582511 |
| 34 | CDC7 | 1.15758524 |
| 35 | ADRBK2 | 1.12183345 |
| 36 | TXK | 1.07224418 |
| 37 | TTK | 1.02599923 |
| 38 | GRK1 | 0.98881341 |
| 39 | PASK | 0.98433468 |
| 40 | WNK4 | 0.93042313 |
| 41 | PIK3CG | 0.89053097 |
| 42 | PLK1 | 0.88817163 |
| 43 | BCR | 0.87819866 |
| 44 | DYRK2 | 0.84621147 |
| 45 | TLK1 | 0.82956692 |
| 46 | STK4 | 0.82358586 |
| 47 | ATR | 0.79080291 |
| 48 | PDK2 | 0.74559964 |
| 49 | CLK1 | 0.73292652 |
| 50 | DYRK3 | 0.68949441 |
| 51 | IRAK1 | 0.65254726 |
| 52 | IKBKE | 0.64946637 |
| 53 | TGFBR1 | 0.64847491 |
| 54 | PAK3 | 0.63790629 |
| 55 | WNK1 | 0.61125293 |
| 56 | CSNK1G2 | 0.60505672 |
| 57 | CSNK1G1 | 0.57608662 |
| 58 | AURKB | 0.57457191 |
| 59 | WEE1 | 0.53818591 |
| 60 | SIK3 | 0.52559621 |
| 61 | ATM | 0.52276759 |
| 62 | CSNK1G3 | 0.51499163 |
| 63 | DAPK1 | 0.51354993 |
| 64 | PIK3CA | 0.51110376 |
| 65 | CSNK1A1L | 0.50840432 |
| 66 | CSNK1E | 0.49441409 |
| 67 | CSNK2A2 | 0.48532956 |
| 68 | ERBB3 | 0.47300663 |
| 69 | IKBKB | 0.43881676 |
| 70 | PHKG2 | 0.42880472 |
| 71 | PHKG1 | 0.42880472 |
| 72 | BRSK2 | 0.41317730 |
| 73 | PRKCE | 0.40060126 |
| 74 | RPS6KA5 | 0.40016037 |
| 75 | JAK3 | 0.39814669 |
| 76 | PRKCG | 0.39404174 |
| 77 | CSNK2A1 | 0.38902489 |
| 78 | ITK | 0.37370380 |
| 79 | PAK4 | 0.37305741 |
| 80 | TIE1 | 0.37012953 |
| 81 | MAP3K12 | 0.35645032 |
| 82 | FGFR1 | 0.35351201 |
| 83 | STK11 | 0.35240101 |
| 84 | GRK5 | 0.35063388 |
| 85 | ADRBK1 | 0.32214652 |
| 86 | EGFR | 0.31415210 |
| 87 | SGK2 | 0.31345177 |
| 88 | MAP2K6 | 0.30727103 |
| 89 | CHEK2 | 0.30689392 |
| 90 | MAP4K2 | 0.29462982 |
| 91 | CHEK1 | 0.29265411 |
| 92 | CDK8 | 0.27898911 |
| 93 | STK3 | 0.27452784 |
| 94 | AKT3 | 0.26927324 |
| 95 | RPS6KA4 | 0.26902996 |
| 96 | DAPK2 | 0.26222658 |
| 97 | CSNK1D | 0.26203094 |
| 98 | STK10 | 0.25238125 |
| 99 | TGFBR2 | 0.24794766 |
| 100 | PNCK | 0.22082825 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.45060931 |
| 2 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 4.33340995 |
| 3 | RNA polymerase_Homo sapiens_hsa03020 | 3.14993931 |
| 4 | Protein export_Homo sapiens_hsa03060 | 3.11034283 |
| 5 | Basal transcription factors_Homo sapiens_hsa03022 | 2.83584595 |
| 6 | RNA degradation_Homo sapiens_hsa03018 | 2.68804815 |
| 7 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.61231769 |
| 8 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.55803245 |
| 9 | RNA transport_Homo sapiens_hsa03013 | 2.44481395 |
| 10 | Mismatch repair_Homo sapiens_hsa03430 | 2.28091970 |
| 11 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.15166523 |
| 12 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.08424221 |
| 13 | Spliceosome_Homo sapiens_hsa03040 | 2.08098694 |
| 14 | Parkinsons disease_Homo sapiens_hsa05012 | 2.04867226 |
| 15 | Homologous recombination_Homo sapiens_hsa03440 | 2.04571000 |
| 16 | Asthma_Homo sapiens_hsa05310 | 2.03836890 |
| 17 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.99298635 |
| 18 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.88779836 |
| 19 | Allograft rejection_Homo sapiens_hsa05330 | 1.84108708 |
| 20 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.81917113 |
| 21 | DNA replication_Homo sapiens_hsa03030 | 1.69316365 |
| 22 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.50747361 |
| 23 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.49821422 |
| 24 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.49277384 |
| 25 | Huntingtons disease_Homo sapiens_hsa05016 | 1.48073993 |
| 26 | Phototransduction_Homo sapiens_hsa04744 | 1.44928989 |
| 27 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.38347003 |
| 28 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.31664470 |
| 29 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.30921401 |
| 30 | Ribosome_Homo sapiens_hsa03010 | 1.30684626 |
| 31 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.24150463 |
| 32 | Purine metabolism_Homo sapiens_hsa00230 | 1.23983851 |
| 33 | Alzheimers disease_Homo sapiens_hsa05010 | 1.23090136 |
| 34 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.22600481 |
| 35 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.18930615 |
| 36 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.14139942 |
| 37 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.13291399 |
| 38 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.12278467 |
| 39 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.07978024 |
| 40 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.00006191 |
| 41 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.99880233 |
| 42 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.99191601 |
| 43 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.97406647 |
| 44 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.95734223 |
| 45 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.94522691 |
| 46 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.93442906 |
| 47 | Cell cycle_Homo sapiens_hsa04110 | 0.92789133 |
| 48 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.85338797 |
| 49 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.85282562 |
| 50 | Measles_Homo sapiens_hsa05162 | 0.84152993 |
| 51 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.82250528 |
| 52 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.81955910 |
| 53 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.76948305 |
| 54 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.75673400 |
| 55 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.72729389 |
| 56 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.68017642 |
| 57 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.67835017 |
| 58 | Base excision repair_Homo sapiens_hsa03410 | 0.63630611 |
| 59 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.61632237 |
| 60 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.59033231 |
| 61 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.58024704 |
| 62 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.56132654 |
| 63 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.55902411 |
| 64 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.55677453 |
| 65 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.55079403 |
| 66 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.53093166 |
| 67 | Peroxisome_Homo sapiens_hsa04146 | 0.52892916 |
| 68 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.52762275 |
| 69 | Legionellosis_Homo sapiens_hsa05134 | 0.49460467 |
| 70 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.45738424 |
| 71 | Metabolic pathways_Homo sapiens_hsa01100 | 0.43704456 |
| 72 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.42191707 |
| 73 | Olfactory transduction_Homo sapiens_hsa04740 | 0.41245455 |
| 74 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.41109024 |
| 75 | Circadian rhythm_Homo sapiens_hsa04710 | 0.41025242 |
| 76 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.40060920 |
| 77 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.39869538 |
| 78 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.39611292 |
| 79 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.39568477 |
| 80 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.38147751 |
| 81 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.35570662 |
| 82 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.34999860 |
| 83 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.30722728 |
| 84 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.28253695 |
| 85 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.27910854 |
| 86 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.27877566 |
| 87 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.26857180 |
| 88 | Taste transduction_Homo sapiens_hsa04742 | 0.26831475 |
| 89 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.24089454 |
| 90 | Carbon metabolism_Homo sapiens_hsa01200 | 0.22994859 |
| 91 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.21502577 |
| 92 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.17803277 |
| 93 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.16728793 |
| 94 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.14796940 |
| 95 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.14614759 |
| 96 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.13985170 |
| 97 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.13604646 |
| 98 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.12578966 |
| 99 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.11884739 |
| 100 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.11591499 |

