

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | rRNA methylation (GO:0031167) | 5.68240689 |
| 2 | rRNA modification (GO:0000154) | 5.56265839 |
| 3 | proteasome assembly (GO:0043248) | 5.06240353 |
| 4 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 4.79912005 |
| 5 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.74751199 |
| 6 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.74751199 |
| 7 | folic acid-containing compound biosynthetic process (GO:0009396) | 4.66157461 |
| 8 | IMP biosynthetic process (GO:0006188) | 4.35744208 |
| 9 | chaperone-mediated protein transport (GO:0072321) | 4.30124401 |
| 10 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 4.28186046 |
| 11 | ribosome biogenesis (GO:0042254) | 4.27244682 |
| 12 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.22807589 |
| 13 | DNA deamination (GO:0045006) | 4.11719187 |
| 14 | ribosomal small subunit assembly (GO:0000028) | 4.08730492 |
| 15 | pseudouridine synthesis (GO:0001522) | 4.07846865 |
| 16 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 4.05187424 |
| 17 | rRNA processing (GO:0006364) | 3.99972253 |
| 18 | GTP biosynthetic process (GO:0006183) | 3.96149067 |
| 19 | mitochondrial RNA metabolic process (GO:0000959) | 3.94876035 |
| 20 | ATP synthesis coupled proton transport (GO:0015986) | 3.93886643 |
| 21 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.93886643 |
| 22 | ribosome assembly (GO:0042255) | 3.93586100 |
| 23 | CENP-A containing nucleosome assembly (GO:0034080) | 3.92730230 |
| 24 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.91431657 |
| 25 | regulation of immunoglobulin secretion (GO:0051023) | 3.84877854 |
| 26 | rRNA metabolic process (GO:0016072) | 3.84096256 |
| 27 | chromatin remodeling at centromere (GO:0031055) | 3.83931541 |
| 28 | ribosomal large subunit biogenesis (GO:0042273) | 3.82920445 |
| 29 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.81042808 |
| 30 | maturation of SSU-rRNA (GO:0030490) | 3.80952390 |
| 31 | IMP metabolic process (GO:0046040) | 3.79243226 |
| 32 | maturation of 5.8S rRNA (GO:0000460) | 3.78164778 |
| 33 | pteridine-containing compound biosynthetic process (GO:0042559) | 3.76018243 |
| 34 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.74804186 |
| 35 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.67713919 |
| 36 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.66556638 |
| 37 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.62737511 |
| 38 | purine nucleotide salvage (GO:0032261) | 3.57860876 |
| 39 | cellular component biogenesis (GO:0044085) | 3.51133141 |
| 40 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.50888200 |
| 41 | UTP biosynthetic process (GO:0006228) | 3.49419099 |
| 42 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.47861375 |
| 43 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.47861375 |
| 44 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.47861375 |
| 45 | termination of RNA polymerase I transcription (GO:0006363) | 3.47380324 |
| 46 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 3.44634516 |
| 47 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.43952542 |
| 48 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.43952542 |
| 49 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.42574229 |
| 50 | UTP metabolic process (GO:0046051) | 3.42213778 |
| 51 | termination of RNA polymerase III transcription (GO:0006386) | 3.42128542 |
| 52 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.42128542 |
| 53 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.40312874 |
| 54 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.38007663 |
| 55 | isotype switching (GO:0045190) | 3.38007663 |
| 56 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.38007663 |
| 57 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.36044912 |
| 58 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.35407398 |
| 59 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.35407398 |
| 60 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.30442599 |
| 61 | histone exchange (GO:0043486) | 3.30216100 |
| 62 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.28294495 |
| 63 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.27363380 |
| 64 | NADH dehydrogenase complex assembly (GO:0010257) | 3.27363380 |
| 65 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.27363380 |
| 66 | positive regulation of isotype switching (GO:0045830) | 3.26471681 |
| 67 | negative regulation of ligase activity (GO:0051352) | 3.24055673 |
| 68 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.24055673 |
| 69 | protein complex biogenesis (GO:0070271) | 3.23819128 |
| 70 | CTP biosynthetic process (GO:0006241) | 3.22693522 |
| 71 | CTP metabolic process (GO:0046036) | 3.22693522 |
| 72 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.19562788 |
| 73 | transcription from mitochondrial promoter (GO:0006390) | 3.18471577 |
| 74 | behavioral response to nicotine (GO:0035095) | 3.17834760 |
| 75 | peptidyl-histidine modification (GO:0018202) | 3.17321705 |
| 76 | protein targeting to mitochondrion (GO:0006626) | 3.16476748 |
| 77 | translation (GO:0006412) | 3.16154939 |
| 78 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.15723789 |
| 79 | ncRNA processing (GO:0034470) | 3.10363349 |
| 80 | protein-cofactor linkage (GO:0018065) | 3.09767455 |
| 81 | DNA double-strand break processing (GO:0000729) | 3.08565544 |
| 82 | positive regulation of DNA recombination (GO:0045911) | 3.08273653 |
| 83 | amino acid salvage (GO:0043102) | 3.06358513 |
| 84 | L-methionine salvage (GO:0071267) | 3.06358513 |
| 85 | L-methionine biosynthetic process (GO:0071265) | 3.06358513 |
| 86 | tRNA processing (GO:0008033) | 3.05651433 |
| 87 | spliceosomal snRNP assembly (GO:0000387) | 3.04919691 |
| 88 | ncRNA metabolic process (GO:0034660) | 3.04578496 |
| 89 | DNA replication checkpoint (GO:0000076) | 3.03765988 |
| 90 | regulation of chronic inflammatory response (GO:0002676) | 3.03556519 |
| 91 | protein localization to mitochondrion (GO:0070585) | 3.02275988 |
| 92 | purine nucleobase biosynthetic process (GO:0009113) | 3.00469762 |
| 93 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.00184067 |
| 94 | tRNA metabolic process (GO:0006399) | 2.98374834 |
| 95 | amino acid activation (GO:0043038) | 2.98035212 |
| 96 | tRNA aminoacylation (GO:0043039) | 2.98035212 |
| 97 | nucleobase biosynthetic process (GO:0046112) | 2.96236050 |
| 98 | tetrahydrofolate metabolic process (GO:0046653) | 2.96097539 |
| 99 | DNA replication-independent nucleosome organization (GO:0034724) | 2.94628217 |
| 100 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.94628217 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 5.97791038 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.02835677 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.86138397 |
| 4 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.49863900 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.09221891 |
| 6 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.74809356 |
| 7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.41691071 |
| 8 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.14446889 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.05476511 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.04567027 |
| 11 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.96402050 |
| 12 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.85756932 |
| 13 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.72949096 |
| 14 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.61968463 |
| 15 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.49891675 |
| 16 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.41247896 |
| 17 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.38150935 |
| 18 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.37855093 |
| 19 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.31545793 |
| 20 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.30757874 |
| 21 | VDR_22108803_ChIP-Seq_LS180_Human | 2.30650026 |
| 22 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.11967870 |
| 23 | TTF2_22483619_ChIP-Seq_HELA_Human | 2.02381356 |
| 24 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.99267502 |
| 25 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.97779327 |
| 26 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.94953176 |
| 27 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.90940737 |
| 28 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.90076699 |
| 29 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.89487784 |
| 30 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.88960729 |
| 31 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.86403934 |
| 32 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.85980767 |
| 33 | EWS_26573619_Chip-Seq_HEK293_Human | 1.85968096 |
| 34 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.85064532 |
| 35 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.79147224 |
| 36 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.77353897 |
| 37 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.76410381 |
| 38 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.72019445 |
| 39 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.64117179 |
| 40 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.58857545 |
| 41 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.54410231 |
| 42 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.52431299 |
| 43 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.49718306 |
| 44 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.46583080 |
| 45 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.43502069 |
| 46 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.43007432 |
| 47 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.42531421 |
| 48 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.38556243 |
| 49 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.38128674 |
| 50 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.35648236 |
| 51 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.29345139 |
| 52 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.29125577 |
| 53 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.28802602 |
| 54 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.26005312 |
| 55 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.25252952 |
| 56 | FUS_26573619_Chip-Seq_HEK293_Human | 1.20488660 |
| 57 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.18841271 |
| 58 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.14098263 |
| 59 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.14021169 |
| 60 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.07891231 |
| 61 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.07853394 |
| 62 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.06512395 |
| 63 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.04019163 |
| 64 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.03900656 |
| 65 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03557095 |
| 66 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.02698686 |
| 67 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.02174994 |
| 68 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.01762955 |
| 69 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 0.98204727 |
| 70 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.97434564 |
| 71 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.92784017 |
| 72 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.92458025 |
| 73 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.89626569 |
| 74 | P300_19829295_ChIP-Seq_ESCs_Human | 0.88053446 |
| 75 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.88026272 |
| 76 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.85978880 |
| 77 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.85958145 |
| 78 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.85293896 |
| 79 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.83093509 |
| 80 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.82192974 |
| 81 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.82192974 |
| 82 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.81905078 |
| 83 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.79814106 |
| 84 | NCOR_22424771_ChIP-Seq_293T_Human | 0.77722021 |
| 85 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.77689433 |
| 86 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.76737951 |
| 87 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.76395888 |
| 88 | EZH2_22144423_ChIP-Seq_EOC_Human | 0.73819329 |
| 89 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.73794123 |
| 90 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.73794123 |
| 91 | GATA3_26560356_Chip-Seq_TH1_Human | 0.73431778 |
| 92 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.73215613 |
| 93 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.72875452 |
| 94 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.72865014 |
| 95 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.72572497 |
| 96 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.71020701 |
| 97 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.70809455 |
| 98 | GATA3_26560356_Chip-Seq_TH2_Human | 0.70296803 |
| 99 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.69569479 |
| 100 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.69390405 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 3.83594227 |
| 2 | MP0006292_abnormal_olfactory_placode | 3.52286562 |
| 3 | MP0008058_abnormal_DNA_repair | 3.24742248 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.07572010 |
| 5 | MP0010094_abnormal_chromosome_stability | 2.89456966 |
| 6 | MP0002102_abnormal_ear_morphology | 2.67068146 |
| 7 | MP0004957_abnormal_blastocyst_morpholog | 2.52315882 |
| 8 | MP0003786_premature_aging | 2.48830175 |
| 9 | MP0003693_abnormal_embryo_hatching | 2.48262501 |
| 10 | MP0008872_abnormal_physiological_respon | 2.27250245 |
| 11 | MP0003806_abnormal_nucleotide_metabolis | 2.26240191 |
| 12 | MP0002938_white_spotting | 2.21512174 |
| 13 | MP0003718_maternal_effect | 2.09772821 |
| 14 | MP0004147_increased_porphyrin_level | 2.01707675 |
| 15 | MP0005670_abnormal_white_adipose | 2.00562986 |
| 16 | MP0006072_abnormal_retinal_apoptosis | 1.96236454 |
| 17 | MP0003186_abnormal_redox_activity | 1.94452357 |
| 18 | MP0008877_abnormal_DNA_methylation | 1.91576913 |
| 19 | MP0003878_abnormal_ear_physiology | 1.88907810 |
| 20 | MP0005377_hearing/vestibular/ear_phenot | 1.88907810 |
| 21 | MP0003111_abnormal_nucleus_morphology | 1.85405727 |
| 22 | MP0002736_abnormal_nociception_after | 1.83319635 |
| 23 | MP0003077_abnormal_cell_cycle | 1.81192448 |
| 24 | MP0008875_abnormal_xenobiotic_pharmacok | 1.72322006 |
| 25 | MP0000685_abnormal_immune_system | 1.72038979 |
| 26 | MP0002006_tumorigenesis | 1.62012536 |
| 27 | MP0008057_abnormal_DNA_replication | 1.60824364 |
| 28 | MP0002234_abnormal_pharynx_morphology | 1.56659678 |
| 29 | MP0008995_early_reproductive_senescence | 1.55838262 |
| 30 | MP0003567_abnormal_fetal_cardiomyocyte | 1.53112315 |
| 31 | MP0001293_anophthalmia | 1.52553622 |
| 32 | MP0005551_abnormal_eye_electrophysiolog | 1.52382266 |
| 33 | MP0002396_abnormal_hematopoietic_system | 1.49724994 |
| 34 | MP0005645_abnormal_hypothalamus_physiol | 1.49083038 |
| 35 | MP0001661_extended_life_span | 1.45109298 |
| 36 | MP0005360_urolithiasis | 1.44700446 |
| 37 | MP0001348_abnormal_lacrimal_gland | 1.41957856 |
| 38 | MP0008789_abnormal_olfactory_epithelium | 1.41601118 |
| 39 | MP0004885_abnormal_endolymph | 1.41412399 |
| 40 | MP0008007_abnormal_cellular_replicative | 1.39416286 |
| 41 | MP0009697_abnormal_copulation | 1.38764759 |
| 42 | MP0005646_abnormal_pituitary_gland | 1.35461810 |
| 43 | MP0001529_abnormal_vocalization | 1.34578643 |
| 44 | MP0001873_stomach_inflammation | 1.33597242 |
| 45 | MP0009333_abnormal_splenocyte_physiolog | 1.32058200 |
| 46 | MP0001853_heart_inflammation | 1.31182969 |
| 47 | MP0003183_abnormal_peptide_metabolism | 1.31043509 |
| 48 | MP0002837_dystrophic_cardiac_calcinosis | 1.30017951 |
| 49 | MP0001968_abnormal_touch/_nociception | 1.29342010 |
| 50 | MP0006036_abnormal_mitochondrial_physio | 1.27689271 |
| 51 | MP0002166_altered_tumor_susceptibility | 1.26604648 |
| 52 | MP0005671_abnormal_response_to | 1.26083842 |
| 53 | MP0001188_hyperpigmentation | 1.25884319 |
| 54 | MP0002163_abnormal_gland_morphology | 1.22977131 |
| 55 | MP0002095_abnormal_skin_pigmentation | 1.18776255 |
| 56 | MP0004142_abnormal_muscle_tone | 1.18378470 |
| 57 | MP0005084_abnormal_gallbladder_morpholo | 1.15350102 |
| 58 | MP0000372_irregular_coat_pigmentation | 1.14855077 |
| 59 | MP0004145_abnormal_muscle_electrophysio | 1.13186115 |
| 60 | MP0005332_abnormal_amino_acid | 1.12291631 |
| 61 | MP0005408_hypopigmentation | 1.10013077 |
| 62 | MP0002160_abnormal_reproductive_system | 1.09842055 |
| 63 | MP0002138_abnormal_hepatobiliary_system | 1.07966331 |
| 64 | MP0002210_abnormal_sex_determination | 1.05578196 |
| 65 | MP0006035_abnormal_mitochondrial_morpho | 1.04825958 |
| 66 | MP0001800_abnormal_humoral_immune | 1.04226579 |
| 67 | MP0005075_abnormal_melanosome_morpholog | 1.02166540 |
| 68 | MP0005174_abnormal_tail_pigmentation | 1.01608475 |
| 69 | MP0003646_muscle_fatigue | 1.01137143 |
| 70 | MP0005253_abnormal_eye_physiology | 0.98897495 |
| 71 | MP0005389_reproductive_system_phenotype | 0.96016461 |
| 72 | MP0005410_abnormal_fertilization | 0.93815600 |
| 73 | MP0008932_abnormal_embryonic_tissue | 0.91774718 |
| 74 | MP0005394_taste/olfaction_phenotype | 0.90494657 |
| 75 | MP0005499_abnormal_olfactory_system | 0.90494657 |
| 76 | MP0000631_abnormal_neuroendocrine_gland | 0.89310201 |
| 77 | MP0001986_abnormal_taste_sensitivity | 0.87451321 |
| 78 | MP0001929_abnormal_gametogenesis | 0.86993323 |
| 79 | MP0005387_immune_system_phenotype | 0.85543630 |
| 80 | MP0001790_abnormal_immune_system | 0.85543630 |
| 81 | MP0000427_abnormal_hair_cycle | 0.84350432 |
| 82 | MP0002148_abnormal_hypersensitivity_rea | 0.83760113 |
| 83 | MP0001502_abnormal_circadian_rhythm | 0.82762146 |
| 84 | MP0000653_abnormal_sex_gland | 0.80777928 |
| 85 | MP0002272_abnormal_nervous_system | 0.79531776 |
| 86 | MP0001764_abnormal_homeostasis | 0.78218602 |
| 87 | MP0001905_abnormal_dopamine_level | 0.77029263 |
| 88 | MP0003195_calcinosis | 0.76943105 |
| 89 | MP0009785_altered_susceptibility_to | 0.75233619 |
| 90 | MP0001145_abnormal_male_reproductive | 0.75151296 |
| 91 | MP0005379_endocrine/exocrine_gland_phen | 0.73957555 |
| 92 | MP0001919_abnormal_reproductive_system | 0.73926674 |
| 93 | MP0001119_abnormal_female_reproductive | 0.72388139 |
| 94 | MP0005636_abnormal_mineral_homeostasis | 0.72086136 |
| 95 | MP0002019_abnormal_tumor_incidence | 0.69088726 |
| 96 | MP0001501_abnormal_sleep_pattern | 0.67920661 |
| 97 | MP0003011_delayed_dark_adaptation | 0.66573939 |
| 98 | MP0006276_abnormal_autonomic_nervous | 0.65715349 |
| 99 | MP0005085_abnormal_gallbladder_physiolo | 0.65477863 |
| 100 | MP0003937_abnormal_limbs/digits/tail_de | 0.65070356 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of alanine metabolism (HP:0010916) | 4.51876114 |
| 2 | Hyperalaninemia (HP:0003348) | 4.51876114 |
| 3 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 4.51876114 |
| 4 | Acute necrotizing encephalopathy (HP:0006965) | 4.19475941 |
| 5 | Stomatitis (HP:0010280) | 3.77038438 |
| 6 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.76098201 |
| 7 | Acute encephalopathy (HP:0006846) | 3.63141036 |
| 8 | Increased CSF lactate (HP:0002490) | 3.49293507 |
| 9 | Mitochondrial inheritance (HP:0001427) | 3.47768262 |
| 10 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.40236202 |
| 11 | Increased hepatocellular lipid droplets (HP:0006565) | 3.39008204 |
| 12 | Progressive macrocephaly (HP:0004481) | 3.38816498 |
| 13 | Abnormality of the labia minora (HP:0012880) | 3.34682756 |
| 14 | Constricted visual fields (HP:0001133) | 3.27692778 |
| 15 | Increased serum lactate (HP:0002151) | 3.10929870 |
| 16 | Lipid accumulation in hepatocytes (HP:0006561) | 3.09119342 |
| 17 | Congenital, generalized hypertrichosis (HP:0004540) | 3.04347744 |
| 18 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.02410518 |
| 19 | 3-Methylglutaconic aciduria (HP:0003535) | 3.00701629 |
| 20 | Cerebral edema (HP:0002181) | 2.98738319 |
| 21 | Abnormality of the pons (HP:0007361) | 2.93611223 |
| 22 | Hepatocellular necrosis (HP:0001404) | 2.90538218 |
| 23 | Colon cancer (HP:0003003) | 2.87174266 |
| 24 | IgG deficiency (HP:0004315) | 2.83832555 |
| 25 | Reticulocytopenia (HP:0001896) | 2.82234102 |
| 26 | Renal Fanconi syndrome (HP:0001994) | 2.74659952 |
| 27 | Meckel diverticulum (HP:0002245) | 2.66241515 |
| 28 | Congenital stationary night blindness (HP:0007642) | 2.60206588 |
| 29 | Hepatic necrosis (HP:0002605) | 2.57326206 |
| 30 | Macrocytic anemia (HP:0001972) | 2.55571314 |
| 31 | Abnormality of serum amino acid levels (HP:0003112) | 2.55117674 |
| 32 | Optic disc pallor (HP:0000543) | 2.53617439 |
| 33 | Oligodactyly (hands) (HP:0001180) | 2.53614275 |
| 34 | Fatigue (HP:0012378) | 2.52476826 |
| 35 | Abnormality of the ileum (HP:0001549) | 2.50441738 |
| 36 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.50277716 |
| 37 | Duplicated collecting system (HP:0000081) | 2.47034724 |
| 38 | Horseshoe kidney (HP:0000085) | 2.46430280 |
| 39 | Lactic acidosis (HP:0003128) | 2.43991750 |
| 40 | Pancreatic cysts (HP:0001737) | 2.40167620 |
| 41 | Exertional dyspnea (HP:0002875) | 2.39138300 |
| 42 | Pendular nystagmus (HP:0012043) | 2.38704781 |
| 43 | Abnormality of midbrain morphology (HP:0002418) | 2.37591474 |
| 44 | Molar tooth sign on MRI (HP:0002419) | 2.37591474 |
| 45 | Hypoplasia of the pons (HP:0012110) | 2.35189309 |
| 46 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.29729097 |
| 47 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.26139679 |
| 48 | Abnormality of the renal collecting system (HP:0004742) | 2.25780382 |
| 49 | Exercise intolerance (HP:0003546) | 2.23699354 |
| 50 | Absent thumb (HP:0009777) | 2.22450414 |
| 51 | Megaloblastic anemia (HP:0001889) | 2.19980288 |
| 52 | Leukodystrophy (HP:0002415) | 2.17478842 |
| 53 | Homocystinuria (HP:0002156) | 2.17131092 |
| 54 | Abnormality of homocysteine metabolism (HP:0010919) | 2.17131092 |
| 55 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.15095905 |
| 56 | Chronic sinusitis (HP:0011109) | 2.14847491 |
| 57 | Multiple enchondromatosis (HP:0005701) | 2.13374018 |
| 58 | Supernumerary spleens (HP:0009799) | 2.10964378 |
| 59 | Abnormality of methionine metabolism (HP:0010901) | 2.08748851 |
| 60 | Abnormality of the preputium (HP:0100587) | 2.07628319 |
| 61 | Stenosis of the external auditory canal (HP:0000402) | 2.05872298 |
| 62 | Methylmalonic acidemia (HP:0002912) | 2.04906966 |
| 63 | Cerebral hypomyelination (HP:0006808) | 2.04886995 |
| 64 | Nephronophthisis (HP:0000090) | 2.02935941 |
| 65 | Lethargy (HP:0001254) | 2.02698478 |
| 66 | Increased IgM level (HP:0003496) | 2.00364495 |
| 67 | Birth length less than 3rd percentile (HP:0003561) | 2.00332408 |
| 68 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 1.97912710 |
| 69 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.97307625 |
| 70 | Triphalangeal thumb (HP:0001199) | 1.95265729 |
| 71 | Oligodactyly (HP:0012165) | 1.93199188 |
| 72 | Abnormality of chromosome stability (HP:0003220) | 1.92814508 |
| 73 | Abnormality of the renal cortex (HP:0011035) | 1.92692773 |
| 74 | Ectopic kidney (HP:0000086) | 1.91706188 |
| 75 | Premature ovarian failure (HP:0008209) | 1.90439928 |
| 76 | Chromsome breakage (HP:0040012) | 1.89660039 |
| 77 | Duodenal stenosis (HP:0100867) | 1.88514738 |
| 78 | Small intestinal stenosis (HP:0012848) | 1.88514738 |
| 79 | Paralysis (HP:0003470) | 1.86651429 |
| 80 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.86146383 |
| 81 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.85027055 |
| 82 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.85027055 |
| 83 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.80828599 |
| 84 | Tubular atrophy (HP:0000092) | 1.79856484 |
| 85 | Oral leukoplakia (HP:0002745) | 1.79709697 |
| 86 | Type II lissencephaly (HP:0007260) | 1.78945141 |
| 87 | Hyperglycinemia (HP:0002154) | 1.78722773 |
| 88 | Abolished electroretinogram (ERG) (HP:0000550) | 1.78658924 |
| 89 | Congenital sensorineural hearing impairment (HP:0008527) | 1.77915356 |
| 90 | Myelodysplasia (HP:0002863) | 1.77413367 |
| 91 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.77349987 |
| 92 | Anorexia (HP:0002039) | 1.77098070 |
| 93 | Hyperglycinuria (HP:0003108) | 1.76207554 |
| 94 | Absent septum pellucidum (HP:0001331) | 1.74650818 |
| 95 | Cleft eyelid (HP:0000625) | 1.74099415 |
| 96 | Clubbing of toes (HP:0100760) | 1.73831248 |
| 97 | Abnormal number of erythroid precursors (HP:0012131) | 1.73619182 |
| 98 | Respiratory failure (HP:0002878) | 1.73591803 |
| 99 | Cortical visual impairment (HP:0100704) | 1.72960263 |
| 100 | Abnormal lung lobation (HP:0002101) | 1.72755190 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TSSK6 | 4.56563143 |
| 2 | MST4 | 4.23048297 |
| 3 | VRK2 | 3.18427557 |
| 4 | EIF2AK1 | 2.96113313 |
| 5 | EIF2AK3 | 2.91792501 |
| 6 | SRPK1 | 2.74963657 |
| 7 | ZAK | 2.54479767 |
| 8 | TRIM28 | 2.46427450 |
| 9 | WNK4 | 2.38546739 |
| 10 | PBK | 2.30682464 |
| 11 | BUB1 | 2.17232487 |
| 12 | PLK3 | 2.16797317 |
| 13 | NUAK1 | 2.13512202 |
| 14 | NME1 | 2.13430389 |
| 15 | TAF1 | 2.06282579 |
| 16 | VRK1 | 1.95751084 |
| 17 | MKNK2 | 1.95624945 |
| 18 | CDC7 | 1.90038886 |
| 19 | STK39 | 1.87217606 |
| 20 | NEK1 | 1.74309590 |
| 21 | PLK4 | 1.73921846 |
| 22 | WNK3 | 1.60491560 |
| 23 | MKNK1 | 1.55057656 |
| 24 | EIF2AK2 | 1.52041349 |
| 25 | TNIK | 1.49550617 |
| 26 | ALK | 1.45594301 |
| 27 | GRK1 | 1.43497345 |
| 28 | TEC | 1.42530344 |
| 29 | BMPR1B | 1.39387337 |
| 30 | ADRBK2 | 1.37086201 |
| 31 | ACVR1B | 1.31012806 |
| 32 | MAP2K6 | 1.28887932 |
| 33 | TLK1 | 1.26353041 |
| 34 | TTK | 1.22885253 |
| 35 | OXSR1 | 1.20815930 |
| 36 | BMPR2 | 1.20199664 |
| 37 | TXK | 1.18219660 |
| 38 | DYRK2 | 1.12693958 |
| 39 | PLK1 | 1.05541394 |
| 40 | ATR | 0.98969188 |
| 41 | WEE1 | 0.94905954 |
| 42 | PASK | 0.93066859 |
| 43 | CDK7 | 0.90832875 |
| 44 | CHEK2 | 0.90412967 |
| 45 | TGFBR1 | 0.86450655 |
| 46 | MAP3K4 | 0.84722484 |
| 47 | PLK2 | 0.83959170 |
| 48 | PIK3CG | 0.82077604 |
| 49 | RPS6KA4 | 0.82063290 |
| 50 | RPS6KB2 | 0.81837967 |
| 51 | STK4 | 0.77603348 |
| 52 | AURKB | 0.75497160 |
| 53 | IKBKB | 0.73442661 |
| 54 | CCNB1 | 0.72280386 |
| 55 | FGFR1 | 0.70439723 |
| 56 | NME2 | 0.68554699 |
| 57 | BCKDK | 0.67767784 |
| 58 | CDK9 | 0.66849661 |
| 59 | MAP2K7 | 0.65941107 |
| 60 | STK16 | 0.64585449 |
| 61 | DYRK3 | 0.62525545 |
| 62 | AKT3 | 0.62055718 |
| 63 | RPS6KA5 | 0.61241769 |
| 64 | JAK3 | 0.59988041 |
| 65 | CSNK2A2 | 0.59848758 |
| 66 | DAPK3 | 0.54262600 |
| 67 | CHEK1 | 0.53779998 |
| 68 | CSNK2A1 | 0.53537702 |
| 69 | ITK | 0.51351748 |
| 70 | WNK1 | 0.50246826 |
| 71 | CSNK1E | 0.47267226 |
| 72 | ADRBK1 | 0.46208629 |
| 73 | PRKCG | 0.41715539 |
| 74 | DAPK1 | 0.41593461 |
| 75 | KIT | 0.41537827 |
| 76 | FLT3 | 0.41437593 |
| 77 | TIE1 | 0.40933012 |
| 78 | CSNK1A1 | 0.39705987 |
| 79 | ATM | 0.39616363 |
| 80 | BRD4 | 0.38518745 |
| 81 | AURKA | 0.35517210 |
| 82 | PDK2 | 0.33882995 |
| 83 | CSNK1G3 | 0.32902544 |
| 84 | PRKCE | 0.32497668 |
| 85 | INSRR | 0.31253435 |
| 86 | CSNK1G1 | 0.30963749 |
| 87 | PIM2 | 0.30753562 |
| 88 | PRKCQ | 0.29888426 |
| 89 | CSNK1G2 | 0.25966853 |
| 90 | STK3 | 0.25593256 |
| 91 | PHKG2 | 0.25359347 |
| 92 | PHKG1 | 0.25359347 |
| 93 | CDK6 | 0.23793559 |
| 94 | EPHB2 | 0.23750042 |
| 95 | MAP2K3 | 0.22391475 |
| 96 | PRKCI | 0.22176673 |
| 97 | CLK1 | 0.22101893 |
| 98 | FGR | 0.22081329 |
| 99 | CDK1 | 0.20596554 |
| 100 | PAK4 | 0.20525841 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.77577058 |
| 2 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.58925820 |
| 3 | Ribosome_Homo sapiens_hsa03010 | 3.40624562 |
| 4 | One carbon pool by folate_Homo sapiens_hsa00670 | 3.03522881 |
| 5 | Protein export_Homo sapiens_hsa03060 | 2.96882196 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.91094480 |
| 7 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.89861893 |
| 8 | Asthma_Homo sapiens_hsa05310 | 2.70036842 |
| 9 | Mismatch repair_Homo sapiens_hsa03430 | 2.62296981 |
| 10 | DNA replication_Homo sapiens_hsa03030 | 2.31940589 |
| 11 | Parkinsons disease_Homo sapiens_hsa05012 | 2.31670546 |
| 12 | RNA degradation_Homo sapiens_hsa03018 | 2.29645793 |
| 13 | Basal transcription factors_Homo sapiens_hsa03022 | 2.28693243 |
| 14 | Homologous recombination_Homo sapiens_hsa03440 | 2.13017088 |
| 15 | RNA transport_Homo sapiens_hsa03013 | 2.04612030 |
| 16 | Spliceosome_Homo sapiens_hsa03040 | 2.04370082 |
| 17 | Allograft rejection_Homo sapiens_hsa05330 | 1.96887387 |
| 18 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.96398227 |
| 19 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.84293581 |
| 20 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.75588648 |
| 21 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.73558524 |
| 22 | Huntingtons disease_Homo sapiens_hsa05016 | 1.72676420 |
| 23 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.68979916 |
| 24 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.67320067 |
| 25 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.56013313 |
| 26 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.43986508 |
| 27 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.42616671 |
| 28 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.41410882 |
| 29 | Base excision repair_Homo sapiens_hsa03410 | 1.40621559 |
| 30 | Alzheimers disease_Homo sapiens_hsa05010 | 1.39968938 |
| 31 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.27728787 |
| 32 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.27300627 |
| 33 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.22322175 |
| 34 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.18650614 |
| 35 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.16974901 |
| 36 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.16551362 |
| 37 | Purine metabolism_Homo sapiens_hsa00230 | 1.13079047 |
| 38 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.12300810 |
| 39 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.09827084 |
| 40 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.05798316 |
| 41 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.00662864 |
| 42 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.98138839 |
| 43 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.95001450 |
| 44 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.91511659 |
| 45 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.88734774 |
| 46 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.88393841 |
| 47 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.86807354 |
| 48 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.85533231 |
| 49 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.77581123 |
| 50 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.76898763 |
| 51 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.74239436 |
| 52 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.65027012 |
| 53 | Peroxisome_Homo sapiens_hsa04146 | 0.63586135 |
| 54 | Phototransduction_Homo sapiens_hsa04744 | 0.63528385 |
| 55 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.63059013 |
| 56 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.60835893 |
| 57 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.60502002 |
| 58 | Cell cycle_Homo sapiens_hsa04110 | 0.58074001 |
| 59 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.57878452 |
| 60 | Metabolic pathways_Homo sapiens_hsa01100 | 0.57393637 |
| 61 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.57059023 |
| 62 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.55475968 |
| 63 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.54716199 |
| 64 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.54239343 |
| 65 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.53392329 |
| 66 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.52053514 |
| 67 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.48563611 |
| 68 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.47252018 |
| 69 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.45414531 |
| 70 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.43295716 |
| 71 | Olfactory transduction_Homo sapiens_hsa04740 | 0.43179465 |
| 72 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.42823059 |
| 73 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.42657511 |
| 74 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.40576435 |
| 75 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.38386062 |
| 76 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.38281577 |
| 77 | Retinol metabolism_Homo sapiens_hsa00830 | 0.38103744 |
| 78 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.37036693 |
| 79 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.35604231 |
| 80 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.34268364 |
| 81 | Carbon metabolism_Homo sapiens_hsa01200 | 0.33785073 |
| 82 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.32223427 |
| 83 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.30803832 |
| 84 | Nicotine addiction_Homo sapiens_hsa05033 | 0.29741428 |
| 85 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.29591643 |
| 86 | Sulfur relay system_Homo sapiens_hsa04122 | 0.27914899 |
| 87 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.27478772 |
| 88 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.26124294 |
| 89 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.25334989 |
| 90 | GABAergic synapse_Homo sapiens_hsa04727 | 0.23971023 |
| 91 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.23206699 |
| 92 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.23201949 |
| 93 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.22565738 |
| 94 | Morphine addiction_Homo sapiens_hsa05032 | 0.22130188 |
| 95 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.19929879 |
| 96 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.19595728 |
| 97 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.19364844 |
| 98 | Measles_Homo sapiens_hsa05162 | 0.19144156 |
| 99 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.18304806 |
| 100 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.17948172 |

