

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 7.00474895 |
| 2 | proteasome assembly (GO:0043248) | 5.32685994 |
| 3 | cytidine metabolic process (GO:0046087) | 4.83274168 |
| 4 | cytidine catabolic process (GO:0006216) | 4.83274168 |
| 5 | cytidine deamination (GO:0009972) | 4.83274168 |
| 6 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.76980559 |
| 7 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.33576652 |
| 8 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.07733131 |
| 9 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.03090672 |
| 10 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.01292842 |
| 11 | ATP synthesis coupled proton transport (GO:0015986) | 4.01292842 |
| 12 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.98354551 |
| 13 | rRNA modification (GO:0000154) | 3.93221103 |
| 14 | platelet dense granule organization (GO:0060155) | 3.82113356 |
| 15 | protein neddylation (GO:0045116) | 3.81813595 |
| 16 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.79168558 |
| 17 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.77700560 |
| 18 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.69185325 |
| 19 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.69185325 |
| 20 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.69185325 |
| 21 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.67236000 |
| 22 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.67236000 |
| 23 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.54451278 |
| 24 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.53107287 |
| 25 | cullin deneddylation (GO:0010388) | 3.48136653 |
| 26 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.47142060 |
| 27 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.47142060 |
| 28 | respiratory chain complex IV assembly (GO:0008535) | 3.46180469 |
| 29 | protein deneddylation (GO:0000338) | 3.44098013 |
| 30 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.43971342 |
| 31 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.42973186 |
| 32 | respiratory electron transport chain (GO:0022904) | 3.42012052 |
| 33 | electron transport chain (GO:0022900) | 3.38852543 |
| 34 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.38803472 |
| 35 | protein complex biogenesis (GO:0070271) | 3.37897269 |
| 36 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.37895194 |
| 37 | negative regulation of ligase activity (GO:0051352) | 3.37724315 |
| 38 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.37724315 |
| 39 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.33289557 |
| 40 | rRNA methylation (GO:0031167) | 3.28019352 |
| 41 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.22068575 |
| 42 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.19214584 |
| 43 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.14334498 |
| 44 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.13171099 |
| 45 | NADH dehydrogenase complex assembly (GO:0010257) | 3.13171099 |
| 46 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.13171099 |
| 47 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.11775534 |
| 48 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.11775534 |
| 49 | chaperone-mediated protein transport (GO:0072321) | 3.10970944 |
| 50 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.06617371 |
| 51 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.04667034 |
| 52 | cytochrome complex assembly (GO:0017004) | 3.02381901 |
| 53 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.01533489 |
| 54 | DNA demethylation (GO:0080111) | 2.98977621 |
| 55 | regulation of chronic inflammatory response (GO:0002676) | 2.94546015 |
| 56 | pseudouridine synthesis (GO:0001522) | 2.94107747 |
| 57 | positive regulation of ligase activity (GO:0051351) | 2.91048086 |
| 58 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.89778519 |
| 59 | positive regulation of protein homodimerization activity (GO:0090073) | 2.89210792 |
| 60 | regulation of cellular amine metabolic process (GO:0033238) | 2.89006131 |
| 61 | L-methionine salvage (GO:0071267) | 2.86672715 |
| 62 | L-methionine biosynthetic process (GO:0071265) | 2.86672715 |
| 63 | amino acid salvage (GO:0043102) | 2.86672715 |
| 64 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.85493538 |
| 65 | positive regulation of cell cycle arrest (GO:0071158) | 2.84260078 |
| 66 | termination of RNA polymerase III transcription (GO:0006386) | 2.80185827 |
| 67 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.80185827 |
| 68 | iron-sulfur cluster assembly (GO:0016226) | 2.78944962 |
| 69 | metallo-sulfur cluster assembly (GO:0031163) | 2.78944962 |
| 70 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.75127247 |
| 71 | ribosomal small subunit assembly (GO:0000028) | 2.73817500 |
| 72 | GPI anchor biosynthetic process (GO:0006506) | 2.71371309 |
| 73 | regulation of regulatory T cell differentiation (GO:0045589) | 2.70216856 |
| 74 | ribosome assembly (GO:0042255) | 2.68079514 |
| 75 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 2.67239858 |
| 76 | S-adenosylmethionine metabolic process (GO:0046500) | 2.66437884 |
| 77 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.65641342 |
| 78 | response to pheromone (GO:0019236) | 2.64655714 |
| 79 | kynurenine metabolic process (GO:0070189) | 2.64259047 |
| 80 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 2.64205376 |
| 81 | negative regulation by host of viral transcription (GO:0043922) | 2.63723335 |
| 82 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.63335153 |
| 83 | isotype switching (GO:0045190) | 2.63335153 |
| 84 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.63335153 |
| 85 | negative regulation of T cell apoptotic process (GO:0070233) | 2.63212934 |
| 86 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 2.62809980 |
| 87 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.61914733 |
| 88 | GPI anchor metabolic process (GO:0006505) | 2.60607707 |
| 89 | DNA dealkylation (GO:0035510) | 2.59564475 |
| 90 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 2.58101129 |
| 91 | tryptophan catabolic process (GO:0006569) | 2.57674675 |
| 92 | indole-containing compound catabolic process (GO:0042436) | 2.57674675 |
| 93 | indolalkylamine catabolic process (GO:0046218) | 2.57674675 |
| 94 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 2.56163610 |
| 95 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 2.53605917 |
| 96 | positive regulation of defense response to virus by host (GO:0002230) | 2.52056342 |
| 97 | maturation of 5.8S rRNA (GO:0000460) | 2.52055623 |
| 98 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.51354254 |
| 99 | aldehyde catabolic process (GO:0046185) | 2.49044759 |
| 100 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 2.45993602 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.32627988 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.06045048 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.32740224 |
| 4 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.06693300 |
| 5 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.03331953 |
| 6 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.99331633 |
| 7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.93222695 |
| 8 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.93188475 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.88491554 |
| 10 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.85922720 |
| 11 | VDR_22108803_ChIP-Seq_LS180_Human | 2.74634040 |
| 12 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.55923257 |
| 13 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.44140561 |
| 14 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.41437182 |
| 15 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.32687603 |
| 16 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.32501926 |
| 17 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.14080646 |
| 18 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.13594805 |
| 19 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.12784838 |
| 20 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.08268052 |
| 21 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.02128353 |
| 22 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.01322152 |
| 23 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.93189382 |
| 24 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.91358126 |
| 25 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.90727048 |
| 26 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.88119185 |
| 27 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.83054898 |
| 28 | EWS_26573619_Chip-Seq_HEK293_Human | 1.76223533 |
| 29 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.68950083 |
| 30 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.61672152 |
| 31 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.57464745 |
| 32 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.56738325 |
| 33 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.53550572 |
| 34 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.50612403 |
| 35 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.50213990 |
| 36 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.49976273 |
| 37 | MYB_26560356_Chip-Seq_TH2_Human | 1.48382410 |
| 38 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.48058745 |
| 39 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.47462320 |
| 40 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.47150267 |
| 41 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.46304390 |
| 42 | FUS_26573619_Chip-Seq_HEK293_Human | 1.43635991 |
| 43 | GATA3_26560356_Chip-Seq_TH2_Human | 1.37856702 |
| 44 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.36061552 |
| 45 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.36061552 |
| 46 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.35120677 |
| 47 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.35043699 |
| 48 | AR_20517297_ChIP-Seq_VCAP_Human | 1.31016131 |
| 49 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.30023562 |
| 50 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.28833882 |
| 51 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.28564489 |
| 52 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.27183123 |
| 53 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.26318461 |
| 54 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.26287111 |
| 55 | P300_19829295_ChIP-Seq_ESCs_Human | 1.25599034 |
| 56 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.25578560 |
| 57 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.25578560 |
| 58 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.24384316 |
| 59 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.24033870 |
| 60 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.23556609 |
| 61 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.23519488 |
| 62 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.21547351 |
| 63 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.21027950 |
| 64 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.19939093 |
| 65 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.18933258 |
| 66 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.18594443 |
| 67 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.18001069 |
| 68 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.14128227 |
| 69 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.14066135 |
| 70 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.13766464 |
| 71 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.13710097 |
| 72 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.13374101 |
| 73 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.13374101 |
| 74 | NCOR_22424771_ChIP-Seq_293T_Human | 1.12811855 |
| 75 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.12358481 |
| 76 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.10272482 |
| 77 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.08996851 |
| 78 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.07980607 |
| 79 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.07627025 |
| 80 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.07513861 |
| 81 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.07128628 |
| 82 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.06400993 |
| 83 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.05873289 |
| 84 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.05086648 |
| 85 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.04931709 |
| 86 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.04321548 |
| 87 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.03358531 |
| 88 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.03126349 |
| 89 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.03111690 |
| 90 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.01569111 |
| 91 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.01222008 |
| 92 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.00251832 |
| 93 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.00047032 |
| 94 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.99415205 |
| 95 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.99116750 |
| 96 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.98286018 |
| 97 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.96330977 |
| 98 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.95510807 |
| 99 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.93591427 |
| 100 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.92280086 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 3.73526231 |
| 2 | MP0001835_abnormal_antigen_presentation | 3.06240892 |
| 3 | MP0002102_abnormal_ear_morphology | 2.45359285 |
| 4 | MP0009785_altered_susceptibility_to | 2.24230511 |
| 5 | MP0005646_abnormal_pituitary_gland | 2.16680382 |
| 6 | MP0004147_increased_porphyrin_level | 2.13872032 |
| 7 | MP0008877_abnormal_DNA_methylation | 2.11518865 |
| 8 | MP0002837_dystrophic_cardiac_calcinosis | 2.09434845 |
| 9 | MP0008058_abnormal_DNA_repair | 2.08578581 |
| 10 | MP0006072_abnormal_retinal_apoptosis | 2.08322054 |
| 11 | MP0000372_irregular_coat_pigmentation | 2.05320214 |
| 12 | MP0005075_abnormal_melanosome_morpholog | 2.02822350 |
| 13 | MP0001873_stomach_inflammation | 2.01144819 |
| 14 | MP0009333_abnormal_splenocyte_physiolog | 1.98682940 |
| 15 | MP0008872_abnormal_physiological_respon | 1.95963689 |
| 16 | MP0002166_altered_tumor_susceptibility | 1.94426400 |
| 17 | MP0008875_abnormal_xenobiotic_pharmacok | 1.91993188 |
| 18 | MP0009697_abnormal_copulation | 1.90324548 |
| 19 | MP0002148_abnormal_hypersensitivity_rea | 1.88213700 |
| 20 | MP0001764_abnormal_homeostasis | 1.87014182 |
| 21 | MP0005084_abnormal_gallbladder_morpholo | 1.85761481 |
| 22 | MP0003786_premature_aging | 1.81922892 |
| 23 | MP0006036_abnormal_mitochondrial_physio | 1.80571218 |
| 24 | MP0001800_abnormal_humoral_immune | 1.76230271 |
| 25 | MP0002006_tumorigenesis | 1.70883437 |
| 26 | MP0003763_abnormal_thymus_physiology | 1.69317848 |
| 27 | MP0002876_abnormal_thyroid_physiology | 1.64047689 |
| 28 | MP0005000_abnormal_immune_tolerance | 1.62473755 |
| 29 | MP0003195_calcinosis | 1.59653739 |
| 30 | MP0005551_abnormal_eye_electrophysiolog | 1.56675563 |
| 31 | MP0005645_abnormal_hypothalamus_physiol | 1.53247514 |
| 32 | MP0001968_abnormal_touch/_nociception | 1.51482449 |
| 33 | MP0006292_abnormal_olfactory_placode | 1.48628490 |
| 34 | MP0003806_abnormal_nucleotide_metabolis | 1.47795721 |
| 35 | MP0002138_abnormal_hepatobiliary_system | 1.45138311 |
| 36 | MP0003646_muscle_fatigue | 1.44192931 |
| 37 | MP0000685_abnormal_immune_system | 1.44121743 |
| 38 | MP0003718_maternal_effect | 1.43865959 |
| 39 | MP0006082_CNS_inflammation | 1.40709390 |
| 40 | MP0005085_abnormal_gallbladder_physiolo | 1.40372295 |
| 41 | MP0002723_abnormal_immune_serum | 1.38873299 |
| 42 | MP0005253_abnormal_eye_physiology | 1.36493851 |
| 43 | MP0002420_abnormal_adaptive_immunity | 1.33352128 |
| 44 | MP0002163_abnormal_gland_morphology | 1.32992044 |
| 45 | MP0002736_abnormal_nociception_after | 1.32212688 |
| 46 | MP0010386_abnormal_urinary_bladder | 1.30425176 |
| 47 | MP0001819_abnormal_immune_cell | 1.30371043 |
| 48 | MP0005389_reproductive_system_phenotype | 1.29499798 |
| 49 | MP0002452_abnormal_antigen_presenting | 1.25655024 |
| 50 | MP0001905_abnormal_dopamine_level | 1.23342385 |
| 51 | MP0003252_abnormal_bile_duct | 1.23091883 |
| 52 | MP0005379_endocrine/exocrine_gland_phen | 1.21821097 |
| 53 | MP0001501_abnormal_sleep_pattern | 1.21313639 |
| 54 | MP0002398_abnormal_bone_marrow | 1.20236116 |
| 55 | MP0005387_immune_system_phenotype | 1.18807206 |
| 56 | MP0001790_abnormal_immune_system | 1.18807206 |
| 57 | MP0003866_abnormal_defecation | 1.18688053 |
| 58 | MP0005025_abnormal_response_to | 1.16769719 |
| 59 | MP0010094_abnormal_chromosome_stability | 1.15776954 |
| 60 | MP0009764_decreased_sensitivity_to | 1.15612359 |
| 61 | MP0002160_abnormal_reproductive_system | 1.15053111 |
| 62 | MP0004145_abnormal_muscle_electrophysio | 1.13149535 |
| 63 | MP0001188_hyperpigmentation | 1.13101418 |
| 64 | MP0002693_abnormal_pancreas_physiology | 1.09795900 |
| 65 | MP0000689_abnormal_spleen_morphology | 1.09555206 |
| 66 | MP0000716_abnormal_immune_system | 1.08356816 |
| 67 | MP0003186_abnormal_redox_activity | 0.99921410 |
| 68 | MP0008057_abnormal_DNA_replication | 0.99506017 |
| 69 | MP0001661_extended_life_span | 0.96867327 |
| 70 | MP0010155_abnormal_intestine_physiology | 0.94702647 |
| 71 | MP0001986_abnormal_taste_sensitivity | 0.94666717 |
| 72 | MP0002277_abnormal_respiratory_mucosa | 0.93737171 |
| 73 | MP0002405_respiratory_system_inflammati | 0.93714768 |
| 74 | MP0001919_abnormal_reproductive_system | 0.93504630 |
| 75 | MP0002722_abnormal_immune_system | 0.92616359 |
| 76 | MP0005636_abnormal_mineral_homeostasis | 0.91637470 |
| 77 | MP0008995_early_reproductive_senescence | 0.91580168 |
| 78 | MP0004885_abnormal_endolymph | 0.91154027 |
| 79 | MP0001845_abnormal_inflammatory_respons | 0.91095615 |
| 80 | MP0006276_abnormal_autonomic_nervous | 0.90500039 |
| 81 | MP0001529_abnormal_vocalization | 0.90055638 |
| 82 | MP0006035_abnormal_mitochondrial_morpho | 0.89184875 |
| 83 | MP0003567_abnormal_fetal_cardiomyocyte | 0.88122264 |
| 84 | MP0002429_abnormal_blood_cell | 0.86865078 |
| 85 | MP0000703_abnormal_thymus_morphology | 0.85898272 |
| 86 | MP0002132_abnormal_respiratory_system | 0.85140231 |
| 87 | MP0000465_gastrointestinal_hemorrhage | 0.81711089 |
| 88 | MP0008469_abnormal_protein_level | 0.81643243 |
| 89 | MP0001119_abnormal_female_reproductive | 0.80701341 |
| 90 | MP0003724_increased_susceptibility_to | 0.80479143 |
| 91 | MP0005174_abnormal_tail_pigmentation | 0.80465055 |
| 92 | MP0004957_abnormal_blastocyst_morpholog | 0.79625528 |
| 93 | MP0002095_abnormal_skin_pigmentation | 0.79478782 |
| 94 | MP0003011_delayed_dark_adaptation | 0.78871137 |
| 95 | MP0003045_fibrosis | 0.78219543 |
| 96 | MP0004043_abnormal_pH_regulation | 0.75300723 |
| 97 | MP0005332_abnormal_amino_acid | 0.73955914 |
| 98 | MP0005410_abnormal_fertilization | 0.73687589 |
| 99 | MP0003137_abnormal_impulse_conducting | 0.72687717 |
| 100 | MP0004142_abnormal_muscle_tone | 0.72132274 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Mitochondrial inheritance (HP:0001427) | 4.19627034 |
| 2 | Aplastic anemia (HP:0001915) | 4.10412101 |
| 3 | Acute necrotizing encephalopathy (HP:0006965) | 4.09150261 |
| 4 | Increased CSF lactate (HP:0002490) | 4.05260164 |
| 5 | Hepatocellular necrosis (HP:0001404) | 4.03790303 |
| 6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.68677198 |
| 7 | Hepatic necrosis (HP:0002605) | 3.65460274 |
| 8 | Acute encephalopathy (HP:0006846) | 3.60556167 |
| 9 | Progressive macrocephaly (HP:0004481) | 3.44602378 |
| 10 | IgG deficiency (HP:0004315) | 3.28713384 |
| 11 | Increased hepatocellular lipid droplets (HP:0006565) | 3.28037621 |
| 12 | Lipid accumulation in hepatocytes (HP:0006561) | 3.08128295 |
| 13 | Abnormality of B cell number (HP:0010975) | 3.01021091 |
| 14 | Severe combined immunodeficiency (HP:0004430) | 2.96253456 |
| 15 | Cerebral edema (HP:0002181) | 2.92314857 |
| 16 | Congenital stationary night blindness (HP:0007642) | 2.91349998 |
| 17 | Hypoproteinemia (HP:0003075) | 2.90510274 |
| 18 | Abnormality of T cell number (HP:0011839) | 2.89101250 |
| 19 | 3-Methylglutaconic aciduria (HP:0003535) | 2.88888184 |
| 20 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.87413586 |
| 21 | Increased serum lactate (HP:0002151) | 2.86333855 |
| 22 | Pancreatic cysts (HP:0001737) | 2.86202062 |
| 23 | Abolished electroretinogram (ERG) (HP:0000550) | 2.82255217 |
| 24 | T lymphocytopenia (HP:0005403) | 2.79148697 |
| 25 | Autoimmune hemolytic anemia (HP:0001890) | 2.74240320 |
| 26 | Congenital, generalized hypertrichosis (HP:0004540) | 2.74160445 |
| 27 | Methylmalonic acidemia (HP:0002912) | 2.70319147 |
| 28 | Abnormality of the prostate (HP:0008775) | 2.67486767 |
| 29 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.67096254 |
| 30 | Abnormality of alanine metabolism (HP:0010916) | 2.67096254 |
| 31 | Hyperalaninemia (HP:0003348) | 2.67096254 |
| 32 | Reduced antithrombin III activity (HP:0001976) | 2.66760944 |
| 33 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.65713392 |
| 34 | Lactic acidosis (HP:0003128) | 2.64362369 |
| 35 | B lymphocytopenia (HP:0010976) | 2.62078965 |
| 36 | Type I transferrin isoform profile (HP:0003642) | 2.61455368 |
| 37 | Thyroiditis (HP:0100646) | 2.60727323 |
| 38 | Decreased central vision (HP:0007663) | 2.54499417 |
| 39 | Methylmalonic aciduria (HP:0012120) | 2.52031664 |
| 40 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.49556736 |
| 41 | Molar tooth sign on MRI (HP:0002419) | 2.46186009 |
| 42 | Abnormality of midbrain morphology (HP:0002418) | 2.46186009 |
| 43 | Increased intramyocellular lipid droplets (HP:0012240) | 2.45809476 |
| 44 | Stomatitis (HP:0010280) | 2.45574993 |
| 45 | Renal Fanconi syndrome (HP:0001994) | 2.45443807 |
| 46 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.44907140 |
| 47 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.44907140 |
| 48 | Optic disc pallor (HP:0000543) | 2.44443643 |
| 49 | Attenuation of retinal blood vessels (HP:0007843) | 2.41432703 |
| 50 | Abnormality of T cells (HP:0002843) | 2.40830448 |
| 51 | Hypothermia (HP:0002045) | 2.40225372 |
| 52 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.38293459 |
| 53 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.38293459 |
| 54 | Abnormal protein glycosylation (HP:0012346) | 2.38293459 |
| 55 | Abnormal glycosylation (HP:0012345) | 2.38293459 |
| 56 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.37681821 |
| 57 | Constricted visual fields (HP:0001133) | 2.34565144 |
| 58 | Respiratory failure (HP:0002878) | 2.32841191 |
| 59 | Lethargy (HP:0001254) | 2.32742906 |
| 60 | True hermaphroditism (HP:0010459) | 2.31660047 |
| 61 | Abnormality of macular pigmentation (HP:0008002) | 2.30613770 |
| 62 | Pancytopenia (HP:0001876) | 2.30118561 |
| 63 | Medial flaring of the eyebrow (HP:0010747) | 2.25780036 |
| 64 | Exertional dyspnea (HP:0002875) | 2.22449006 |
| 65 | CNS demyelination (HP:0007305) | 2.21555243 |
| 66 | Increased IgM level (HP:0003496) | 2.21352927 |
| 67 | Oral leukoplakia (HP:0002745) | 2.19197467 |
| 68 | Pancreatic fibrosis (HP:0100732) | 2.18833563 |
| 69 | Combined immunodeficiency (HP:0005387) | 2.16547350 |
| 70 | Nephronophthisis (HP:0000090) | 2.15931459 |
| 71 | Abnormality of eosinophils (HP:0001879) | 2.04395576 |
| 72 | Hyperglycinemia (HP:0002154) | 2.01775563 |
| 73 | Increased muscle lipid content (HP:0009058) | 2.01449783 |
| 74 | Ketoacidosis (HP:0001993) | 2.00121382 |
| 75 | Autoimmune thrombocytopenia (HP:0001973) | 1.98135660 |
| 76 | Type 2 muscle fiber atrophy (HP:0003554) | 1.97797448 |
| 77 | Ketosis (HP:0001946) | 1.97382607 |
| 78 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.94301268 |
| 79 | Dicarboxylic aciduria (HP:0003215) | 1.94301268 |
| 80 | Colon cancer (HP:0003003) | 1.92818363 |
| 81 | Abnormality of T cell physiology (HP:0011840) | 1.91330800 |
| 82 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.90689549 |
| 83 | Abnormality of serum amino acid levels (HP:0003112) | 1.89726029 |
| 84 | Generalized aminoaciduria (HP:0002909) | 1.88941692 |
| 85 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.87037344 |
| 86 | Renal cortical cysts (HP:0000803) | 1.86240804 |
| 87 | Abnormality of the renal cortex (HP:0011035) | 1.85868982 |
| 88 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.85512956 |
| 89 | Leukodystrophy (HP:0002415) | 1.83219001 |
| 90 | Chronic sinusitis (HP:0011109) | 1.82442068 |
| 91 | IgM deficiency (HP:0002850) | 1.80744935 |
| 92 | Exercise intolerance (HP:0003546) | 1.79110838 |
| 93 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.77794118 |
| 94 | Abnormality of glycine metabolism (HP:0010895) | 1.77794118 |
| 95 | Metaphyseal dysplasia (HP:0100255) | 1.75439118 |
| 96 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.74353735 |
| 97 | Abnormality of the renal medulla (HP:0100957) | 1.73687053 |
| 98 | Congenital primary aphakia (HP:0007707) | 1.72451823 |
| 99 | Hyperglycinuria (HP:0003108) | 1.72257441 |
| 100 | Glycosuria (HP:0003076) | 1.72084945 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 3.98350621 |
| 2 | VRK2 | 2.92632476 |
| 3 | EIF2AK3 | 2.80649742 |
| 4 | TAOK3 | 2.79550142 |
| 5 | KDR | 2.61737260 |
| 6 | ZAK | 2.56466489 |
| 7 | MAP4K2 | 2.49707159 |
| 8 | FRK | 2.32278220 |
| 9 | ADRBK2 | 2.30546688 |
| 10 | MST4 | 2.28660138 |
| 11 | BCKDK | 2.26863475 |
| 12 | TLK1 | 2.24915354 |
| 13 | NUAK1 | 2.09937835 |
| 14 | VRK1 | 1.97222316 |
| 15 | STK16 | 1.80398007 |
| 16 | GRK1 | 1.80081829 |
| 17 | BUB1 | 1.62070907 |
| 18 | PINK1 | 1.60409119 |
| 19 | DAPK1 | 1.53265456 |
| 20 | BMPR2 | 1.53175542 |
| 21 | DAPK2 | 1.48411653 |
| 22 | ITK | 1.42920174 |
| 23 | CDK19 | 1.42256765 |
| 24 | ERBB3 | 1.41715767 |
| 25 | CSNK1G1 | 1.35900779 |
| 26 | SCYL2 | 1.30672671 |
| 27 | TEC | 1.26391034 |
| 28 | TSSK6 | 1.20363986 |
| 29 | MAP3K12 | 1.19663646 |
| 30 | CSNK1G3 | 1.17827139 |
| 31 | TESK2 | 1.16587450 |
| 32 | PLK3 | 1.15847232 |
| 33 | OXSR1 | 1.14491596 |
| 34 | TRIM28 | 1.13296371 |
| 35 | MAPKAPK3 | 1.11793684 |
| 36 | MAP4K1 | 1.10770460 |
| 37 | EIF2AK1 | 1.09352952 |
| 38 | BCR | 1.05924000 |
| 39 | INSRR | 1.04411577 |
| 40 | WNK4 | 1.00657819 |
| 41 | WNK3 | 1.00289664 |
| 42 | CSNK1G2 | 0.97477692 |
| 43 | NME1 | 0.96756875 |
| 44 | KIT | 0.95104497 |
| 45 | CSNK1A1L | 0.94999899 |
| 46 | SYK | 0.92313254 |
| 47 | SRPK1 | 0.92258588 |
| 48 | BMPR1B | 0.91751334 |
| 49 | TAF1 | 0.89543996 |
| 50 | PASK | 0.87995017 |
| 51 | MKNK1 | 0.87923162 |
| 52 | RPS6KA4 | 0.86587773 |
| 53 | EIF2AK2 | 0.86407309 |
| 54 | STK39 | 0.86163609 |
| 55 | PLK2 | 0.85977322 |
| 56 | NLK | 0.85117098 |
| 57 | TIE1 | 0.84001911 |
| 58 | PLK4 | 0.76581751 |
| 59 | IKBKB | 0.75992384 |
| 60 | MYLK | 0.71046643 |
| 61 | PRKCQ | 0.68466831 |
| 62 | TRPM7 | 0.68205512 |
| 63 | GRK6 | 0.66434008 |
| 64 | MKNK2 | 0.65888393 |
| 65 | LCK | 0.65736200 |
| 66 | CDC7 | 0.64613713 |
| 67 | FES | 0.62510866 |
| 68 | NEK1 | 0.61277672 |
| 69 | RIPK4 | 0.60852029 |
| 70 | RPS6KA5 | 0.60760367 |
| 71 | IKBKE | 0.58506365 |
| 72 | LIMK1 | 0.56017905 |
| 73 | CSF1R | 0.55979116 |
| 74 | PDK2 | 0.55924750 |
| 75 | FLT3 | 0.54333733 |
| 76 | PRKCE | 0.53942970 |
| 77 | LYN | 0.53431097 |
| 78 | GRK7 | 0.51560988 |
| 79 | PHKG1 | 0.51168220 |
| 80 | PHKG2 | 0.51168220 |
| 81 | DAPK3 | 0.50690010 |
| 82 | MAPKAPK5 | 0.49302942 |
| 83 | OBSCN | 0.48971695 |
| 84 | PLK1 | 0.48355020 |
| 85 | BTK | 0.48079175 |
| 86 | CCNB1 | 0.48043580 |
| 87 | ATR | 0.46928160 |
| 88 | STK38L | 0.45235349 |
| 89 | GRK5 | 0.45139327 |
| 90 | MAP3K4 | 0.44662613 |
| 91 | ACVR1B | 0.44613909 |
| 92 | MAPK13 | 0.43421015 |
| 93 | CSNK2A1 | 0.43390273 |
| 94 | PBK | 0.43211692 |
| 95 | MATK | 0.42205558 |
| 96 | MUSK | 0.41463755 |
| 97 | IGF1R | 0.41408129 |
| 98 | PIK3CG | 0.41283000 |
| 99 | CSNK1A1 | 0.38461794 |
| 100 | CSNK2A2 | 0.35709433 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.04572563 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.14304974 |
| 3 | Asthma_Homo sapiens_hsa05310 | 2.88935981 |
| 4 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.81071290 |
| 5 | Protein export_Homo sapiens_hsa03060 | 2.75860055 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.63999902 |
| 7 | Allograft rejection_Homo sapiens_hsa05330 | 2.63913640 |
| 8 | Parkinsons disease_Homo sapiens_hsa05012 | 2.61702688 |
| 9 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.35971853 |
| 10 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.27785461 |
| 11 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.16139844 |
| 12 | RNA polymerase_Homo sapiens_hsa03020 | 2.14854020 |
| 13 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.90754176 |
| 14 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.85650312 |
| 15 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.79719117 |
| 16 | Homologous recombination_Homo sapiens_hsa03440 | 1.76594184 |
| 17 | Ribosome_Homo sapiens_hsa03010 | 1.76101486 |
| 18 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.71070022 |
| 19 | Huntingtons disease_Homo sapiens_hsa05016 | 1.66524228 |
| 20 | Alzheimers disease_Homo sapiens_hsa05010 | 1.62011645 |
| 21 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.56121951 |
| 22 | RNA degradation_Homo sapiens_hsa03018 | 1.54445771 |
| 23 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.53742312 |
| 24 | DNA replication_Homo sapiens_hsa03030 | 1.51457457 |
| 25 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.43153065 |
| 26 | Mismatch repair_Homo sapiens_hsa03430 | 1.37389371 |
| 27 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.35482122 |
| 28 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.31015858 |
| 29 | Phototransduction_Homo sapiens_hsa04744 | 1.28153985 |
| 30 | Basal transcription factors_Homo sapiens_hsa03022 | 1.27748896 |
| 31 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.21123833 |
| 32 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.19047439 |
| 33 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.18039854 |
| 34 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.17850616 |
| 35 | RNA transport_Homo sapiens_hsa03013 | 1.16021498 |
| 36 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.15040457 |
| 37 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.10581929 |
| 38 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.10191128 |
| 39 | Base excision repair_Homo sapiens_hsa03410 | 1.08502542 |
| 40 | Purine metabolism_Homo sapiens_hsa00230 | 1.02124964 |
| 41 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.00981840 |
| 42 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.00169876 |
| 43 | Spliceosome_Homo sapiens_hsa03040 | 0.99963949 |
| 44 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.96759582 |
| 45 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.94558258 |
| 46 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.94482863 |
| 47 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.93446491 |
| 48 | Peroxisome_Homo sapiens_hsa04146 | 0.91048573 |
| 49 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.89411279 |
| 50 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.88382137 |
| 51 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.84432466 |
| 52 | Viral myocarditis_Homo sapiens_hsa05416 | 0.83146033 |
| 53 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.82316920 |
| 54 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.81907700 |
| 55 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.81776428 |
| 56 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.77736624 |
| 57 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.73300996 |
| 58 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.72802282 |
| 59 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.71617585 |
| 60 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.70106651 |
| 61 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.68844484 |
| 62 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.67313345 |
| 63 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.67067392 |
| 64 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.66026180 |
| 65 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.65579936 |
| 66 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.64718385 |
| 67 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.64119868 |
| 68 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.62410799 |
| 69 | Olfactory transduction_Homo sapiens_hsa04740 | 0.61784466 |
| 70 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.59720084 |
| 71 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.59312174 |
| 72 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.58836902 |
| 73 | Metabolic pathways_Homo sapiens_hsa01100 | 0.58508121 |
| 74 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.57923512 |
| 75 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.57663876 |
| 76 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.56189293 |
| 77 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.53536280 |
| 78 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.52354165 |
| 79 | Retinol metabolism_Homo sapiens_hsa00830 | 0.52138189 |
| 80 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.51320394 |
| 81 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.50593248 |
| 82 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.50169116 |
| 83 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.49765744 |
| 84 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.46019974 |
| 85 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.45890960 |
| 86 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.44838763 |
| 87 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.44274736 |
| 88 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.42570589 |
| 89 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.42267913 |
| 90 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.39462669 |
| 91 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.38364408 |
| 92 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.36394110 |
| 93 | Taste transduction_Homo sapiens_hsa04742 | 0.35398350 |
| 94 | Measles_Homo sapiens_hsa05162 | 0.35052152 |
| 95 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.32528450 |
| 96 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.31706479 |
| 97 | Legionellosis_Homo sapiens_hsa05134 | 0.30719083 |
| 98 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.29954993 |
| 99 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.27716882 |
| 100 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.25453176 |

