

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | proteasome assembly (GO:0043248) | 6.21107970 |
| 2 | DNA deamination (GO:0045006) | 6.10204548 |
| 3 | rRNA modification (GO:0000154) | 5.26348632 |
| 4 | ribosome assembly (GO:0042255) | 4.97740295 |
| 5 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.88355249 |
| 6 | rRNA methylation (GO:0031167) | 4.84228189 |
| 7 | maturation of 5.8S rRNA (GO:0000460) | 4.77445081 |
| 8 | IMP biosynthetic process (GO:0006188) | 4.73745131 |
| 9 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 4.66602786 |
| 10 | cullin deneddylation (GO:0010388) | 4.59602472 |
| 11 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 4.40128692 |
| 12 | chaperone-mediated protein transport (GO:0072321) | 4.33823843 |
| 13 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.29825994 |
| 14 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 4.15504058 |
| 15 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 4.15504058 |
| 16 | isotype switching (GO:0045190) | 4.15504058 |
| 17 | protein deneddylation (GO:0000338) | 4.10845065 |
| 18 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.05446263 |
| 19 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 4.03851558 |
| 20 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 4.00765272 |
| 21 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 4.00765272 |
| 22 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 4.00765272 |
| 23 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.96605062 |
| 24 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.96605062 |
| 25 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.94328817 |
| 26 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.90380055 |
| 27 | IMP metabolic process (GO:0046040) | 3.87214153 |
| 28 | negative regulation of ligase activity (GO:0051352) | 3.87028883 |
| 29 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.87028883 |
| 30 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.83000160 |
| 31 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.82518367 |
| 32 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.82518367 |
| 33 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.79942242 |
| 34 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.77107233 |
| 35 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.76338970 |
| 36 | regulation of chronic inflammatory response (GO:0002676) | 3.74535997 |
| 37 | amino acid activation (GO:0043038) | 3.71221449 |
| 38 | tRNA aminoacylation (GO:0043039) | 3.71221449 |
| 39 | transcription from mitochondrial promoter (GO:0006390) | 3.70919515 |
| 40 | respiratory chain complex IV assembly (GO:0008535) | 3.69617232 |
| 41 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.68954786 |
| 42 | chromatin remodeling at centromere (GO:0031055) | 3.68831056 |
| 43 | DNA replication checkpoint (GO:0000076) | 3.66306285 |
| 44 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.65857297 |
| 45 | ribosome biogenesis (GO:0042254) | 3.65315746 |
| 46 | GTP biosynthetic process (GO:0006183) | 3.63013729 |
| 47 | CENP-A containing nucleosome assembly (GO:0034080) | 3.62280359 |
| 48 | pseudouridine synthesis (GO:0001522) | 3.61145875 |
| 49 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.60855258 |
| 50 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.59805555 |
| 51 | tRNA aminoacylation for protein translation (GO:0006418) | 3.59604535 |
| 52 | rRNA processing (GO:0006364) | 3.57143405 |
| 53 | nucleobase biosynthetic process (GO:0046112) | 3.52867591 |
| 54 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.51612208 |
| 55 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.51238064 |
| 56 | ATP synthesis coupled proton transport (GO:0015986) | 3.51238064 |
| 57 | protein neddylation (GO:0045116) | 3.50736711 |
| 58 | rRNA metabolic process (GO:0016072) | 3.48254659 |
| 59 | purine nucleobase biosynthetic process (GO:0009113) | 3.47772270 |
| 60 | protein complex biogenesis (GO:0070271) | 3.47617902 |
| 61 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 3.47192324 |
| 62 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.45863747 |
| 63 | pteridine-containing compound biosynthetic process (GO:0042559) | 3.44173169 |
| 64 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.43369921 |
| 65 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.42612705 |
| 66 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.42612705 |
| 67 | NADH dehydrogenase complex assembly (GO:0010257) | 3.42612705 |
| 68 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.38607192 |
| 69 | mitotic metaphase plate congression (GO:0007080) | 3.37590646 |
| 70 | UTP biosynthetic process (GO:0006228) | 3.36990845 |
| 71 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.33820793 |
| 72 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.32456640 |
| 73 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.32456640 |
| 74 | termination of RNA polymerase III transcription (GO:0006386) | 3.31918051 |
| 75 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.31918051 |
| 76 | positive regulation of ligase activity (GO:0051351) | 3.27602458 |
| 77 | somatic recombination of immunoglobulin gene segments (GO:0016447) | 3.26285206 |
| 78 | termination of RNA polymerase I transcription (GO:0006363) | 3.25565441 |
| 79 | protein targeting to mitochondrion (GO:0006626) | 3.25381093 |
| 80 | tRNA metabolic process (GO:0006399) | 3.24219770 |
| 81 | cytidine metabolic process (GO:0046087) | 3.22604296 |
| 82 | cytidine catabolic process (GO:0006216) | 3.22604296 |
| 83 | cytidine deamination (GO:0009972) | 3.22604296 |
| 84 | DNA damage response, detection of DNA damage (GO:0042769) | 3.21415255 |
| 85 | mitochondrial RNA metabolic process (GO:0000959) | 3.17299222 |
| 86 | regulation of immunoglobulin secretion (GO:0051023) | 3.16272941 |
| 87 | somatic diversification of immunoglobulins (GO:0016445) | 3.16112545 |
| 88 | positive regulation of cell cycle arrest (GO:0071158) | 3.14690657 |
| 89 | histone exchange (GO:0043486) | 3.13685802 |
| 90 | regulation of helicase activity (GO:0051095) | 3.13109755 |
| 91 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.11084935 |
| 92 | cytochrome complex assembly (GO:0017004) | 3.10796572 |
| 93 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.10062042 |
| 94 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.10062042 |
| 95 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.09261221 |
| 96 | DNA double-strand break processing (GO:0000729) | 3.07834941 |
| 97 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 3.07210359 |
| 98 | tRNA processing (GO:0008033) | 3.05431077 |
| 99 | UTP metabolic process (GO:0046051) | 3.04823504 |
| 100 | ncRNA metabolic process (GO:0034660) | 3.03764037 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.74518823 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.73286659 |
| 3 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.39536369 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.00168838 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.56857684 |
| 6 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.36540386 |
| 7 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.25777542 |
| 8 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.10571874 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.10018694 |
| 10 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.03234341 |
| 11 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.98959754 |
| 12 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.90634344 |
| 13 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.59099862 |
| 14 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.51860902 |
| 15 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.45941863 |
| 16 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.38229852 |
| 17 | VDR_22108803_ChIP-Seq_LS180_Human | 2.36849114 |
| 18 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.30894809 |
| 19 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.27693282 |
| 20 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.25093560 |
| 21 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.22525284 |
| 22 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.16101563 |
| 23 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.05370739 |
| 24 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 2.05037866 |
| 25 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.01368833 |
| 26 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.99878370 |
| 27 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.96312751 |
| 28 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.93101541 |
| 29 | EWS_26573619_Chip-Seq_HEK293_Human | 1.93006016 |
| 30 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.92501992 |
| 31 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.91639304 |
| 32 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.90503077 |
| 33 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.89255367 |
| 34 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.89017798 |
| 35 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.85778462 |
| 36 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.81034601 |
| 37 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.79298048 |
| 38 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.72821060 |
| 39 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.72570750 |
| 40 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.70595903 |
| 41 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.67627222 |
| 42 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.61712550 |
| 43 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.60731265 |
| 44 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.56725369 |
| 45 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.53134319 |
| 46 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.50405815 |
| 47 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.50158575 |
| 48 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.40476159 |
| 49 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.40273385 |
| 50 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.40109456 |
| 51 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.38100746 |
| 52 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.34306525 |
| 53 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.31841386 |
| 54 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.31755411 |
| 55 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.31281526 |
| 56 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.28482213 |
| 57 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.27384176 |
| 58 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.27205850 |
| 59 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.25533745 |
| 60 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.24734207 |
| 61 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.23767870 |
| 62 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.23565074 |
| 63 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.21513038 |
| 64 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.15541646 |
| 65 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.13157871 |
| 66 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.11749224 |
| 67 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.10757266 |
| 68 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.09406033 |
| 69 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.08376093 |
| 70 | FUS_26573619_Chip-Seq_HEK293_Human | 1.08024608 |
| 71 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.05235065 |
| 72 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.02550677 |
| 73 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.02550677 |
| 74 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.99170028 |
| 75 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.99170028 |
| 76 | P300_19829295_ChIP-Seq_ESCs_Human | 0.99116820 |
| 77 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.98637889 |
| 78 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.98222289 |
| 79 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.97637523 |
| 80 | GATA1_22025678_ChIP-Seq_K562_Human | 0.95209882 |
| 81 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.91285201 |
| 82 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.90565962 |
| 83 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.89881639 |
| 84 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.88971403 |
| 85 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.88764649 |
| 86 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.87912292 |
| 87 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.87849087 |
| 88 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.85468026 |
| 89 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.85243858 |
| 90 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.84966010 |
| 91 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.83628519 |
| 92 | GATA3_26560356_Chip-Seq_TH2_Human | 0.81243917 |
| 93 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.80561365 |
| 94 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.80304830 |
| 95 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.80109787 |
| 96 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.79595722 |
| 97 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.78543004 |
| 98 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.78258777 |
| 99 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.77559727 |
| 100 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.77431137 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0010094_abnormal_chromosome_stability | 3.82048858 |
| 2 | MP0003693_abnormal_embryo_hatching | 3.55648854 |
| 3 | MP0004957_abnormal_blastocyst_morpholog | 3.48878836 |
| 4 | MP0008058_abnormal_DNA_repair | 3.47777659 |
| 5 | MP0002102_abnormal_ear_morphology | 3.34044550 |
| 6 | MP0000685_abnormal_immune_system | 3.33925084 |
| 7 | MP0008057_abnormal_DNA_replication | 2.76837715 |
| 8 | MP0001835_abnormal_antigen_presentation | 2.72303062 |
| 9 | MP0003786_premature_aging | 2.57752390 |
| 10 | MP0003718_maternal_effect | 2.51607151 |
| 11 | MP0008877_abnormal_DNA_methylation | 2.36868836 |
| 12 | MP0003806_abnormal_nucleotide_metabolis | 2.32983739 |
| 13 | MP0003077_abnormal_cell_cycle | 2.30688888 |
| 14 | MP0004145_abnormal_muscle_electrophysio | 2.16686484 |
| 15 | MP0008007_abnormal_cellular_replicative | 2.13493808 |
| 16 | MP0003111_abnormal_nucleus_morphology | 2.09828528 |
| 17 | MP0003567_abnormal_fetal_cardiomyocyte | 2.02951260 |
| 18 | MP0006292_abnormal_olfactory_placode | 2.00510407 |
| 19 | MP0006036_abnormal_mitochondrial_physio | 1.99042391 |
| 20 | MP0002736_abnormal_nociception_after | 1.97013523 |
| 21 | MP0006035_abnormal_mitochondrial_morpho | 1.92584013 |
| 22 | MP0005084_abnormal_gallbladder_morpholo | 1.92390354 |
| 23 | MP0002138_abnormal_hepatobiliary_system | 1.82618446 |
| 24 | MP0009697_abnormal_copulation | 1.77361603 |
| 25 | MP0003646_muscle_fatigue | 1.75599298 |
| 26 | MP0008872_abnormal_physiological_respon | 1.75332360 |
| 27 | MP0003195_calcinosis | 1.74970569 |
| 28 | MP0001853_heart_inflammation | 1.60822011 |
| 29 | MP0008875_abnormal_xenobiotic_pharmacok | 1.57745130 |
| 30 | MP0008932_abnormal_embryonic_tissue | 1.55606690 |
| 31 | MP0001293_anophthalmia | 1.49657839 |
| 32 | MP0001968_abnormal_touch/_nociception | 1.48251849 |
| 33 | MP0000372_irregular_coat_pigmentation | 1.34629269 |
| 34 | MP0002006_tumorigenesis | 1.33709322 |
| 35 | MP0001501_abnormal_sleep_pattern | 1.33432458 |
| 36 | MP0002148_abnormal_hypersensitivity_rea | 1.33304732 |
| 37 | MP0001529_abnormal_vocalization | 1.26969456 |
| 38 | MP0002160_abnormal_reproductive_system | 1.24684573 |
| 39 | MP0003878_abnormal_ear_physiology | 1.23578577 |
| 40 | MP0005377_hearing/vestibular/ear_phenot | 1.23578577 |
| 41 | MP0005671_abnormal_response_to | 1.17626937 |
| 42 | MP0003186_abnormal_redox_activity | 1.10994845 |
| 43 | MP0005387_immune_system_phenotype | 1.08582645 |
| 44 | MP0001790_abnormal_immune_system | 1.08582645 |
| 45 | MP0001485_abnormal_pinna_reflex | 1.08236994 |
| 46 | MP0006072_abnormal_retinal_apoptosis | 1.07185542 |
| 47 | MP0003252_abnormal_bile_duct | 1.04310922 |
| 48 | MP0009764_decreased_sensitivity_to | 1.03021255 |
| 49 | MP0004084_abnormal_cardiac_muscle | 1.00627788 |
| 50 | MP0002837_dystrophic_cardiac_calcinosis | 0.98930120 |
| 51 | MP0005389_reproductive_system_phenotype | 0.98214221 |
| 52 | MP0005636_abnormal_mineral_homeostasis | 0.97346726 |
| 53 | MP0009785_altered_susceptibility_to | 0.97155116 |
| 54 | MP0002163_abnormal_gland_morphology | 0.96947373 |
| 55 | MP0004147_increased_porphyrin_level | 0.96512781 |
| 56 | MP0000358_abnormal_cell_content/ | 0.93972950 |
| 57 | MP0002210_abnormal_sex_determination | 0.93123590 |
| 58 | MP0002166_altered_tumor_susceptibility | 0.92204584 |
| 59 | MP0005165_increased_susceptibility_to | 0.90259280 |
| 60 | MP0004215_abnormal_myocardial_fiber | 0.90233978 |
| 61 | MP0009333_abnormal_splenocyte_physiolog | 0.90216131 |
| 62 | MP0005645_abnormal_hypothalamus_physiol | 0.89882881 |
| 63 | MP0003011_delayed_dark_adaptation | 0.88881112 |
| 64 | MP0001697_abnormal_embryo_size | 0.88370095 |
| 65 | MP0003937_abnormal_limbs/digits/tail_de | 0.88090834 |
| 66 | MP0001929_abnormal_gametogenesis | 0.87386095 |
| 67 | MP0001348_abnormal_lacrimal_gland | 0.85532029 |
| 68 | MP0006054_spinal_hemorrhage | 0.84816784 |
| 69 | MP0005395_other_phenotype | 0.83527300 |
| 70 | MP0001730_embryonic_growth_arrest | 0.83010252 |
| 71 | MP0001119_abnormal_female_reproductive | 0.78343835 |
| 72 | MP0001800_abnormal_humoral_immune | 0.76459342 |
| 73 | MP0010386_abnormal_urinary_bladder | 0.76257754 |
| 74 | MP0005085_abnormal_gallbladder_physiolo | 0.76112135 |
| 75 | MP0001905_abnormal_dopamine_level | 0.75470993 |
| 76 | MP0000647_abnormal_sebaceous_gland | 0.75061122 |
| 77 | MP0002254_reproductive_system_inflammat | 0.73821764 |
| 78 | MP0002938_white_spotting | 0.73781071 |
| 79 | MP0002751_abnormal_autonomic_nervous | 0.73694107 |
| 80 | MP0005379_endocrine/exocrine_gland_phen | 0.73496584 |
| 81 | MP0002396_abnormal_hematopoietic_system | 0.73105281 |
| 82 | MP0002277_abnormal_respiratory_mucosa | 0.71837861 |
| 83 | MP0005380_embryogenesis_phenotype | 0.71606761 |
| 84 | MP0001672_abnormal_embryogenesis/_devel | 0.71606761 |
| 85 | MP0000653_abnormal_sex_gland | 0.71540823 |
| 86 | MP0003890_abnormal_embryonic-extraembry | 0.71317061 |
| 87 | MP0008789_abnormal_olfactory_epithelium | 0.71203645 |
| 88 | MP0004133_heterotaxia | 0.69846393 |
| 89 | MP0005332_abnormal_amino_acid | 0.68449902 |
| 90 | MP0002019_abnormal_tumor_incidence | 0.66931923 |
| 91 | MP0003119_abnormal_digestive_system | 0.66702027 |
| 92 | MP0005551_abnormal_eye_electrophysiolog | 0.66316946 |
| 93 | MP0001881_abnormal_mammary_gland | 0.65986706 |
| 94 | MP0002405_respiratory_system_inflammati | 0.65619266 |
| 95 | MP0000689_abnormal_spleen_morphology | 0.65504526 |
| 96 | MP0003936_abnormal_reproductive_system | 0.64928153 |
| 97 | MP0000490_abnormal_crypts_of | 0.64451979 |
| 98 | MP0000427_abnormal_hair_cycle | 0.64197623 |
| 99 | MP0001764_abnormal_homeostasis | 0.64105269 |
| 100 | MP0001145_abnormal_male_reproductive | 0.63946958 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.75175233 |
| 2 | Increased CSF lactate (HP:0002490) | 4.14916117 |
| 3 | Acute encephalopathy (HP:0006846) | 4.09969799 |
| 4 | Progressive macrocephaly (HP:0004481) | 3.98721098 |
| 5 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.94072565 |
| 6 | Stomatitis (HP:0010280) | 3.87528283 |
| 7 | Mitochondrial inheritance (HP:0001427) | 3.86753935 |
| 8 | Increased hepatocellular lipid droplets (HP:0006565) | 3.70716920 |
| 9 | Increased serum pyruvate (HP:0003542) | 3.55544336 |
| 10 | Methylmalonic acidemia (HP:0002912) | 3.52299423 |
| 11 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.47454616 |
| 12 | Abnormality of alanine metabolism (HP:0010916) | 3.47454616 |
| 13 | Hyperalaninemia (HP:0003348) | 3.47454616 |
| 14 | Cerebral edema (HP:0002181) | 3.31468961 |
| 15 | Lipid accumulation in hepatocytes (HP:0006561) | 3.26301588 |
| 16 | Hepatocellular necrosis (HP:0001404) | 3.25649028 |
| 17 | Abnormality of glycolysis (HP:0004366) | 3.21935636 |
| 18 | Abnormality of the labia minora (HP:0012880) | 3.18805856 |
| 19 | Cerebral hypomyelination (HP:0006808) | 3.12628821 |
| 20 | Premature ovarian failure (HP:0008209) | 3.09225352 |
| 21 | Hepatic necrosis (HP:0002605) | 3.08327352 |
| 22 | Increased serum lactate (HP:0002151) | 2.98145178 |
| 23 | Microvesicular hepatic steatosis (HP:0001414) | 2.94092269 |
| 24 | Colon cancer (HP:0003003) | 2.92332705 |
| 25 | 3-Methylglutaconic aciduria (HP:0003535) | 2.90875856 |
| 26 | Methylmalonic aciduria (HP:0012120) | 2.88002428 |
| 27 | Pancreatic cysts (HP:0001737) | 2.79310325 |
| 28 | Congenital, generalized hypertrichosis (HP:0004540) | 2.76948451 |
| 29 | Optic disc pallor (HP:0000543) | 2.71800395 |
| 30 | Renal Fanconi syndrome (HP:0001994) | 2.70681439 |
| 31 | Abnormality of the pons (HP:0007361) | 2.63561826 |
| 32 | Hypoplasia of the pons (HP:0012110) | 2.62839614 |
| 33 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.57037919 |
| 34 | Leukodystrophy (HP:0002415) | 2.48452782 |
| 35 | Supernumerary spleens (HP:0009799) | 2.47789180 |
| 36 | Respiratory difficulties (HP:0002880) | 2.42195716 |
| 37 | Bile duct proliferation (HP:0001408) | 2.39094746 |
| 38 | Abnormal biliary tract physiology (HP:0012439) | 2.39094746 |
| 39 | Meckel diverticulum (HP:0002245) | 2.36074307 |
| 40 | Lactic acidosis (HP:0003128) | 2.35170760 |
| 41 | Lethargy (HP:0001254) | 2.34646322 |
| 42 | Secondary amenorrhea (HP:0000869) | 2.34338987 |
| 43 | Multiple enchondromatosis (HP:0005701) | 2.33982238 |
| 44 | Birth length less than 3rd percentile (HP:0003561) | 2.26397055 |
| 45 | Type 2 muscle fiber atrophy (HP:0003554) | 2.24209337 |
| 46 | Neoplasm of the adrenal gland (HP:0100631) | 2.19125214 |
| 47 | Exertional dyspnea (HP:0002875) | 2.19122531 |
| 48 | Molar tooth sign on MRI (HP:0002419) | 2.19009026 |
| 49 | Abnormality of midbrain morphology (HP:0002418) | 2.19009026 |
| 50 | Increased IgM level (HP:0003496) | 2.18869917 |
| 51 | Abnormality of the ileum (HP:0001549) | 2.17415419 |
| 52 | Respiratory failure (HP:0002878) | 2.16323374 |
| 53 | Abnormality of methionine metabolism (HP:0010901) | 2.14771996 |
| 54 | Exercise intolerance (HP:0003546) | 2.14660567 |
| 55 | IgG deficiency (HP:0004315) | 2.14615044 |
| 56 | Abnormality of serum amino acid levels (HP:0003112) | 2.13978502 |
| 57 | CNS demyelination (HP:0007305) | 2.12444108 |
| 58 | Paralysis (HP:0003470) | 2.11902052 |
| 59 | CNS hypomyelination (HP:0003429) | 2.10909104 |
| 60 | Pancreatic fibrosis (HP:0100732) | 2.09590404 |
| 61 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.07630647 |
| 62 | Abnormality of the anterior horn cell (HP:0006802) | 2.05820959 |
| 63 | Degeneration of anterior horn cells (HP:0002398) | 2.05820959 |
| 64 | Nausea (HP:0002018) | 2.05805069 |
| 65 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.04138926 |
| 66 | Dicarboxylic aciduria (HP:0003215) | 1.98961038 |
| 67 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.98961038 |
| 68 | Abnormality of the preputium (HP:0100587) | 1.98500037 |
| 69 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.98044770 |
| 70 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.97510869 |
| 71 | Muscle fiber atrophy (HP:0100295) | 1.92569676 |
| 72 | Glycosuria (HP:0003076) | 1.92533692 |
| 73 | Abnormality of urine glucose concentration (HP:0011016) | 1.92533692 |
| 74 | Oral leukoplakia (HP:0002745) | 1.92440712 |
| 75 | Pancytopenia (HP:0001876) | 1.92417700 |
| 76 | Pendular nystagmus (HP:0012043) | 1.91291504 |
| 77 | Prostate neoplasm (HP:0100787) | 1.90640006 |
| 78 | Ependymoma (HP:0002888) | 1.89186900 |
| 79 | Amniotic constriction ring (HP:0009775) | 1.87638227 |
| 80 | Abnormality of placental membranes (HP:0011409) | 1.87638227 |
| 81 | Testicular atrophy (HP:0000029) | 1.87057153 |
| 82 | Abnormality of vitamin B metabolism (HP:0004340) | 1.86932830 |
| 83 | Cleft eyelid (HP:0000625) | 1.85979695 |
| 84 | Hypomagnesemia (HP:0002917) | 1.85300963 |
| 85 | Opisthotonus (HP:0002179) | 1.85145476 |
| 86 | Prominent metopic ridge (HP:0005487) | 1.83717088 |
| 87 | Clubbing of toes (HP:0100760) | 1.83381745 |
| 88 | Agnosia (HP:0010524) | 1.80954659 |
| 89 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.80196221 |
| 90 | Hyperglycinuria (HP:0003108) | 1.79413806 |
| 91 | Horseshoe kidney (HP:0000085) | 1.78988667 |
| 92 | Abnormality of T cell physiology (HP:0011840) | 1.78530912 |
| 93 | Abnormality of chromosome stability (HP:0003220) | 1.78340908 |
| 94 | True hermaphroditism (HP:0010459) | 1.78253654 |
| 95 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.77873978 |
| 96 | Abnormality of glycine metabolism (HP:0010895) | 1.77873978 |
| 97 | Duodenal stenosis (HP:0100867) | 1.77031273 |
| 98 | Small intestinal stenosis (HP:0012848) | 1.77031273 |
| 99 | Progressive microcephaly (HP:0000253) | 1.76630516 |
| 100 | Nephronophthisis (HP:0000090) | 1.75951878 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TSSK6 | 4.26271351 |
| 2 | MST4 | 4.05773300 |
| 3 | VRK2 | 3.90225584 |
| 4 | EIF2AK1 | 3.34601962 |
| 5 | TAF1 | 3.25943489 |
| 6 | EIF2AK3 | 3.20055916 |
| 7 | BUB1 | 2.88659186 |
| 8 | TRIM28 | 2.87386133 |
| 9 | NEK1 | 2.66790727 |
| 10 | NUAK1 | 2.64826823 |
| 11 | STK16 | 2.48875935 |
| 12 | PLK3 | 2.48255225 |
| 13 | ZAK | 2.14205507 |
| 14 | VRK1 | 2.04221641 |
| 15 | PBK | 2.03814410 |
| 16 | NME1 | 2.03772259 |
| 17 | FRK | 2.01243692 |
| 18 | MKNK2 | 2.00294479 |
| 19 | MKNK1 | 1.92981954 |
| 20 | SRPK1 | 1.82122999 |
| 21 | PLK2 | 1.74261674 |
| 22 | CDC7 | 1.73820831 |
| 23 | ADRBK2 | 1.70655634 |
| 24 | BMPR1B | 1.64239530 |
| 25 | TTK | 1.46189801 |
| 26 | PLK4 | 1.43248015 |
| 27 | OXSR1 | 1.41383700 |
| 28 | GRK1 | 1.38848641 |
| 29 | ALK | 1.35920484 |
| 30 | EIF2AK2 | 1.35409900 |
| 31 | PDK2 | 1.33570316 |
| 32 | TLK1 | 1.24355934 |
| 33 | DAPK1 | 1.24202015 |
| 34 | ACVR1B | 1.16652117 |
| 35 | PASK | 1.15396695 |
| 36 | SMG1 | 1.11962807 |
| 37 | MAPKAPK5 | 1.11836590 |
| 38 | BCKDK | 1.06881883 |
| 39 | STK39 | 1.06111799 |
| 40 | PLK1 | 1.05969488 |
| 41 | WNK3 | 1.02364252 |
| 42 | DAPK2 | 1.00872579 |
| 43 | MAPKAPK3 | 1.00019346 |
| 44 | TNIK | 0.99818130 |
| 45 | WNK4 | 0.98602121 |
| 46 | WEE1 | 0.91737729 |
| 47 | TAOK3 | 0.91262303 |
| 48 | CSNK1A1L | 0.87508632 |
| 49 | CSNK1G3 | 0.86808050 |
| 50 | DYRK2 | 0.86253182 |
| 51 | PAK4 | 0.84270657 |
| 52 | CSNK1G1 | 0.82235399 |
| 53 | MAP4K2 | 0.76467405 |
| 54 | CSNK1G2 | 0.75476013 |
| 55 | TGFBR1 | 0.73868858 |
| 56 | ATR | 0.73804403 |
| 57 | TEC | 0.70441534 |
| 58 | PHKG1 | 0.70264433 |
| 59 | PHKG2 | 0.70264433 |
| 60 | PNCK | 0.67903459 |
| 61 | SIK3 | 0.62892058 |
| 62 | AURKB | 0.62129368 |
| 63 | PINK1 | 0.59768202 |
| 64 | INSRR | 0.57165083 |
| 65 | NME2 | 0.56097954 |
| 66 | RPS6KA4 | 0.55951512 |
| 67 | CDK19 | 0.55191904 |
| 68 | STK4 | 0.54669002 |
| 69 | TXK | 0.53366629 |
| 70 | RPS6KB2 | 0.51840340 |
| 71 | FGFR1 | 0.44771079 |
| 72 | DAPK3 | 0.44322415 |
| 73 | BCR | 0.43023193 |
| 74 | IKBKB | 0.42305313 |
| 75 | CSNK1E | 0.42102579 |
| 76 | GRK5 | 0.40729380 |
| 77 | CSNK2A1 | 0.38632024 |
| 78 | CSNK2A2 | 0.38346805 |
| 79 | CDK7 | 0.38346250 |
| 80 | CHEK2 | 0.38160119 |
| 81 | PRKCI | 0.36224129 |
| 82 | RPS6KA5 | 0.35757099 |
| 83 | PRKCG | 0.35319542 |
| 84 | STK10 | 0.35282310 |
| 85 | ATM | 0.35205418 |
| 86 | CHEK1 | 0.34398515 |
| 87 | PRKCQ | 0.32055488 |
| 88 | BRSK2 | 0.29930253 |
| 89 | CDK6 | 0.29004403 |
| 90 | TIE1 | 0.26783661 |
| 91 | CDK8 | 0.25724478 |
| 92 | MAP3K8 | 0.24824830 |
| 93 | ADRBK1 | 0.22037359 |
| 94 | PRKCE | 0.20649250 |
| 95 | CSNK1A1 | 0.17182701 |
| 96 | STK38L | 0.16967436 |
| 97 | CAMK2A | 0.16209551 |
| 98 | PRKDC | 0.16116031 |
| 99 | ERBB3 | 0.15914447 |
| 100 | STK3 | 0.15382264 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.25813391 |
| 2 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.79403904 |
| 3 | Protein export_Homo sapiens_hsa03060 | 2.84454835 |
| 4 | Mismatch repair_Homo sapiens_hsa03430 | 2.79472023 |
| 5 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.72339108 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.60179959 |
| 7 | RNA degradation_Homo sapiens_hsa03018 | 2.48656040 |
| 8 | DNA replication_Homo sapiens_hsa03030 | 2.47548521 |
| 9 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.46653255 |
| 10 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 2.43348550 |
| 11 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.36652585 |
| 12 | Basal transcription factors_Homo sapiens_hsa03022 | 2.25530697 |
| 13 | RNA transport_Homo sapiens_hsa03013 | 2.23530995 |
| 14 | Parkinsons disease_Homo sapiens_hsa05012 | 2.14805182 |
| 15 | Asthma_Homo sapiens_hsa05310 | 2.12555778 |
| 16 | Homologous recombination_Homo sapiens_hsa03440 | 2.10475422 |
| 17 | Ribosome_Homo sapiens_hsa03010 | 2.06911988 |
| 18 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.94620943 |
| 19 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.83460209 |
| 20 | Base excision repair_Homo sapiens_hsa03410 | 1.80740549 |
| 21 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.80427816 |
| 22 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.80394111 |
| 23 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.61506322 |
| 24 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.56891808 |
| 25 | Spliceosome_Homo sapiens_hsa03040 | 1.54999885 |
| 26 | Huntingtons disease_Homo sapiens_hsa05016 | 1.51319035 |
| 27 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.48693264 |
| 28 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.42583656 |
| 29 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.38005758 |
| 30 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.37334261 |
| 31 | Allograft rejection_Homo sapiens_hsa05330 | 1.35573698 |
| 32 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.35434582 |
| 33 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.30480496 |
| 34 | Alzheimers disease_Homo sapiens_hsa05010 | 1.27539500 |
| 35 | Purine metabolism_Homo sapiens_hsa00230 | 1.26993292 |
| 36 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.26980356 |
| 37 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.24786127 |
| 38 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.22079220 |
| 39 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.22013188 |
| 40 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.07049441 |
| 41 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.03310523 |
| 42 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.00279080 |
| 43 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.00081983 |
| 44 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.99479789 |
| 45 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.84380582 |
| 46 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.82614910 |
| 47 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.74443995 |
| 48 | Cell cycle_Homo sapiens_hsa04110 | 0.73968720 |
| 49 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.73513796 |
| 50 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.72910778 |
| 51 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.72348222 |
| 52 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.70816461 |
| 53 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.70652059 |
| 54 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.69949686 |
| 55 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.69677115 |
| 56 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.65437780 |
| 57 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.64403793 |
| 58 | Peroxisome_Homo sapiens_hsa04146 | 0.61370530 |
| 59 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.57982697 |
| 60 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.57616691 |
| 61 | Phototransduction_Homo sapiens_hsa04744 | 0.55653746 |
| 62 | Metabolic pathways_Homo sapiens_hsa01100 | 0.55640067 |
| 63 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.55624668 |
| 64 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.55533912 |
| 65 | Carbon metabolism_Homo sapiens_hsa01200 | 0.53190670 |
| 66 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.53082213 |
| 67 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.52939844 |
| 68 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.51980130 |
| 69 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.51716293 |
| 70 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.50863715 |
| 71 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.50836542 |
| 72 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.49088468 |
| 73 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.47406910 |
| 74 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.46419881 |
| 75 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.41472425 |
| 76 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.40480205 |
| 77 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.39946042 |
| 78 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.39239775 |
| 79 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.39145636 |
| 80 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.38753307 |
| 81 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.38680399 |
| 82 | Sulfur relay system_Homo sapiens_hsa04122 | 0.38314803 |
| 83 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.37203564 |
| 84 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.34154524 |
| 85 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.33533167 |
| 86 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.33147331 |
| 87 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.30537748 |
| 88 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.30157967 |
| 89 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.29724672 |
| 90 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.29506092 |
| 91 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.26797862 |
| 92 | Retinol metabolism_Homo sapiens_hsa00830 | 0.26031192 |
| 93 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.25320750 |
| 94 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.24254595 |
| 95 | Olfactory transduction_Homo sapiens_hsa04740 | 0.23820510 |
| 96 | Viral myocarditis_Homo sapiens_hsa05416 | 0.23524295 |
| 97 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.22856491 |
| 98 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.20972277 |
| 99 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.20773706 |
| 100 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.20109938 |

