

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | proteasome assembly (GO:0043248) | 5.09758419 |
| 2 | DNA deamination (GO:0045006) | 5.01706103 |
| 3 | chaperone-mediated protein transport (GO:0072321) | 4.74264504 |
| 4 | rRNA modification (GO:0000154) | 4.41104786 |
| 5 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.27437911 |
| 6 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.26121474 |
| 7 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 4.24965699 |
| 8 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.13643397 |
| 9 | ATP synthesis coupled proton transport (GO:0015986) | 4.13643397 |
| 10 | cullin deneddylation (GO:0010388) | 4.02009788 |
| 11 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.00460602 |
| 12 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.98718715 |
| 13 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.98067744 |
| 14 | rRNA methylation (GO:0031167) | 3.96687361 |
| 15 | protein deneddylation (GO:0000338) | 3.94380492 |
| 16 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.94190883 |
| 17 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.91349741 |
| 18 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.71459023 |
| 19 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.68161745 |
| 20 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.68161745 |
| 21 | NADH dehydrogenase complex assembly (GO:0010257) | 3.68161745 |
| 22 | negative regulation of ligase activity (GO:0051352) | 3.62031712 |
| 23 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.62031712 |
| 24 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.60967474 |
| 25 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.55288685 |
| 26 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.55183530 |
| 27 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.51762801 |
| 28 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.51762801 |
| 29 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.51762801 |
| 30 | maturation of 5.8S rRNA (GO:0000460) | 3.49342502 |
| 31 | regulation of chronic inflammatory response (GO:0002676) | 3.46995336 |
| 32 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.45709421 |
| 33 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.45709421 |
| 34 | isotype switching (GO:0045190) | 3.45709421 |
| 35 | ribosome assembly (GO:0042255) | 3.45577172 |
| 36 | regulation of immunoglobulin secretion (GO:0051023) | 3.44799210 |
| 37 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.44603087 |
| 38 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.44603087 |
| 39 | protein complex biogenesis (GO:0070271) | 3.44509954 |
| 40 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.43915276 |
| 41 | DNA double-strand break processing (GO:0000729) | 3.43355289 |
| 42 | protein neddylation (GO:0045116) | 3.41810242 |
| 43 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.40088177 |
| 44 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.32997349 |
| 45 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.32997349 |
| 46 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.32832296 |
| 47 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.30370738 |
| 48 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.27359393 |
| 49 | termination of RNA polymerase III transcription (GO:0006386) | 3.24027669 |
| 50 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.24027669 |
| 51 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.23588129 |
| 52 | respiratory chain complex IV assembly (GO:0008535) | 3.20350766 |
| 53 | peptidyl-histidine modification (GO:0018202) | 3.17473092 |
| 54 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.16359907 |
| 55 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.16133841 |
| 56 | pseudouridine synthesis (GO:0001522) | 3.15258507 |
| 57 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.11841159 |
| 58 | electron transport chain (GO:0022900) | 3.09071481 |
| 59 | respiratory electron transport chain (GO:0022904) | 3.07801843 |
| 60 | positive regulation of ligase activity (GO:0051351) | 3.02850456 |
| 61 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 2.98743700 |
| 62 | synapsis (GO:0007129) | 2.97559422 |
| 63 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.96039391 |
| 64 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.96039391 |
| 65 | IMP biosynthetic process (GO:0006188) | 2.95478443 |
| 66 | ribosomal large subunit biogenesis (GO:0042273) | 2.89795357 |
| 67 | protein-cofactor linkage (GO:0018065) | 2.86871692 |
| 68 | intracellular protein transmembrane import (GO:0044743) | 2.86616461 |
| 69 | rRNA processing (GO:0006364) | 2.86516683 |
| 70 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.84905862 |
| 71 | mitochondrial RNA metabolic process (GO:0000959) | 2.83436383 |
| 72 | protein targeting to mitochondrion (GO:0006626) | 2.81963341 |
| 73 | rRNA metabolic process (GO:0016072) | 2.81450575 |
| 74 | GTP biosynthetic process (GO:0006183) | 2.78873302 |
| 75 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.76651623 |
| 76 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.76651623 |
| 77 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.75952564 |
| 78 | organelle disassembly (GO:1903008) | 2.75326064 |
| 79 | regulation of cellular amine metabolic process (GO:0033238) | 2.75135399 |
| 80 | tRNA processing (GO:0008033) | 2.72818832 |
| 81 | ribosomal small subunit assembly (GO:0000028) | 2.72091505 |
| 82 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.71253095 |
| 83 | positive regulation of DNA recombination (GO:0045911) | 2.70201942 |
| 84 | chromatin remodeling at centromere (GO:0031055) | 2.69383992 |
| 85 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 2.69314612 |
| 86 | positive regulation of B cell mediated immunity (GO:0002714) | 2.69314612 |
| 87 | positive regulation of cell cycle arrest (GO:0071158) | 2.69272576 |
| 88 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.68912819 |
| 89 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.67813797 |
| 90 | positive regulation of interleukin-17 production (GO:0032740) | 2.67211733 |
| 91 | CENP-A containing nucleosome assembly (GO:0034080) | 2.66799642 |
| 92 | positive regulation of isotype switching (GO:0045830) | 2.65790183 |
| 93 | mannosylation (GO:0097502) | 2.64165212 |
| 94 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.62947282 |
| 95 | establishment of protein localization to mitochondrion (GO:0072655) | 2.62515213 |
| 96 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.62424554 |
| 97 | cytochrome complex assembly (GO:0017004) | 2.62004245 |
| 98 | regulation of ligase activity (GO:0051340) | 2.61871544 |
| 99 | aldehyde catabolic process (GO:0046185) | 2.61392879 |
| 100 | nucleobase biosynthetic process (GO:0046112) | 2.59766362 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.91082673 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.36864841 |
| 3 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.97222150 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.86637932 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.05500538 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.00175523 |
| 7 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.88053217 |
| 8 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.82366975 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.66907873 |
| 10 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.62030305 |
| 11 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.57094126 |
| 12 | VDR_22108803_ChIP-Seq_LS180_Human | 2.55947207 |
| 13 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.48850643 |
| 14 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.42857577 |
| 15 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.39155343 |
| 16 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.37304303 |
| 17 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.32211444 |
| 18 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.31346121 |
| 19 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.18955424 |
| 20 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.16226819 |
| 21 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.08339061 |
| 22 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.00431592 |
| 23 | EWS_26573619_Chip-Seq_HEK293_Human | 1.98421544 |
| 24 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.95442463 |
| 25 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.86340004 |
| 26 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.76939322 |
| 27 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.76178373 |
| 28 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.69230075 |
| 29 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.62707373 |
| 30 | FUS_26573619_Chip-Seq_HEK293_Human | 1.62542662 |
| 31 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.60497888 |
| 32 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.55254163 |
| 33 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.55226844 |
| 34 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.53580034 |
| 35 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.52464150 |
| 36 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.51765640 |
| 37 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.51623337 |
| 38 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.45741424 |
| 39 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.45490812 |
| 40 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.44885784 |
| 41 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.43693794 |
| 42 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.42996847 |
| 43 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.39963261 |
| 44 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.38726818 |
| 45 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.38265183 |
| 46 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.37898170 |
| 47 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.37600174 |
| 48 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.37600174 |
| 49 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.34606250 |
| 50 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.29764729 |
| 51 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.28511110 |
| 52 | GATA3_26560356_Chip-Seq_TH2_Human | 1.27817157 |
| 53 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.27810873 |
| 54 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.27286763 |
| 55 | P300_19829295_ChIP-Seq_ESCs_Human | 1.26248986 |
| 56 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.26107318 |
| 57 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.23731453 |
| 58 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.23115986 |
| 59 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.23115986 |
| 60 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.22135732 |
| 61 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.21869805 |
| 62 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.21395509 |
| 63 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.20530667 |
| 64 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.17509818 |
| 65 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.17472372 |
| 66 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.16716216 |
| 67 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.12845538 |
| 68 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.12796129 |
| 69 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.11706812 |
| 70 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.09243658 |
| 71 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.08454719 |
| 72 | AR_20517297_ChIP-Seq_VCAP_Human | 1.07481505 |
| 73 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.05748849 |
| 74 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.05196252 |
| 75 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.03610833 |
| 76 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.00200380 |
| 77 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.98833670 |
| 78 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.98555331 |
| 79 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.97176874 |
| 80 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.97004306 |
| 81 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.96381972 |
| 82 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.96355796 |
| 83 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 0.95315880 |
| 84 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.94526764 |
| 85 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.93593989 |
| 86 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.93092815 |
| 87 | GATA1_22025678_ChIP-Seq_K562_Human | 0.92907113 |
| 88 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.92125892 |
| 89 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.91653670 |
| 90 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.91653670 |
| 91 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.91204958 |
| 92 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.90786682 |
| 93 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.90345337 |
| 94 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.89608274 |
| 95 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.88043875 |
| 96 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.87969427 |
| 97 | MYB_26560356_Chip-Seq_TH2_Human | 0.87954830 |
| 98 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.87822416 |
| 99 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.87210937 |
| 100 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.86748528 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001835_abnormal_antigen_presentation | 3.55203665 |
| 2 | MP0008877_abnormal_DNA_methylation | 3.30786209 |
| 3 | MP0002102_abnormal_ear_morphology | 2.93354356 |
| 4 | MP0005671_abnormal_response_to | 2.91374566 |
| 5 | MP0008058_abnormal_DNA_repair | 2.59697291 |
| 6 | MP0003786_premature_aging | 2.45356749 |
| 7 | MP0005075_abnormal_melanosome_morpholog | 2.40536842 |
| 8 | MP0003718_maternal_effect | 2.40439425 |
| 9 | MP0008875_abnormal_xenobiotic_pharmacok | 2.39035547 |
| 10 | MP0006072_abnormal_retinal_apoptosis | 2.38449531 |
| 11 | MP0008872_abnormal_physiological_respon | 2.24999592 |
| 12 | MP0010094_abnormal_chromosome_stability | 2.21188631 |
| 13 | MP0004147_increased_porphyrin_level | 2.13148553 |
| 14 | MP0003195_calcinosis | 2.04530846 |
| 15 | MP0003806_abnormal_nucleotide_metabolis | 2.04187496 |
| 16 | MP0002148_abnormal_hypersensitivity_rea | 2.00726442 |
| 17 | MP0000685_abnormal_immune_system | 1.98007433 |
| 18 | MP0006292_abnormal_olfactory_placode | 1.89476132 |
| 19 | MP0006036_abnormal_mitochondrial_physio | 1.83420327 |
| 20 | MP0005084_abnormal_gallbladder_morpholo | 1.76167432 |
| 21 | MP0001873_stomach_inflammation | 1.75810155 |
| 22 | MP0003646_muscle_fatigue | 1.74249963 |
| 23 | MP0003693_abnormal_embryo_hatching | 1.72737129 |
| 24 | MP0006035_abnormal_mitochondrial_morpho | 1.68231654 |
| 25 | MP0002736_abnormal_nociception_after | 1.66586088 |
| 26 | MP0004957_abnormal_blastocyst_morpholog | 1.64641836 |
| 27 | MP0000372_irregular_coat_pigmentation | 1.59490684 |
| 28 | MP0008007_abnormal_cellular_replicative | 1.56994087 |
| 29 | MP0001968_abnormal_touch/_nociception | 1.51028751 |
| 30 | MP0001501_abnormal_sleep_pattern | 1.48388482 |
| 31 | MP0001293_anophthalmia | 1.46149665 |
| 32 | MP0001800_abnormal_humoral_immune | 1.46083198 |
| 33 | MP0002876_abnormal_thyroid_physiology | 1.44000785 |
| 34 | MP0002006_tumorigenesis | 1.43904522 |
| 35 | MP0008057_abnormal_DNA_replication | 1.43829094 |
| 36 | MP0009785_altered_susceptibility_to | 1.43440191 |
| 37 | MP0005646_abnormal_pituitary_gland | 1.42886657 |
| 38 | MP0009333_abnormal_splenocyte_physiolog | 1.42414724 |
| 39 | MP0009697_abnormal_copulation | 1.40553397 |
| 40 | MP0005389_reproductive_system_phenotype | 1.40213876 |
| 41 | MP0005551_abnormal_eye_electrophysiolog | 1.36589393 |
| 42 | MP0002163_abnormal_gland_morphology | 1.34353558 |
| 43 | MP0002160_abnormal_reproductive_system | 1.34239773 |
| 44 | MP0002837_dystrophic_cardiac_calcinosis | 1.31939820 |
| 45 | MP0002938_white_spotting | 1.26245430 |
| 46 | MP0002138_abnormal_hepatobiliary_system | 1.26037414 |
| 47 | MP0001790_abnormal_immune_system | 1.24683619 |
| 48 | MP0005387_immune_system_phenotype | 1.24683619 |
| 49 | MP0001986_abnormal_taste_sensitivity | 1.24256773 |
| 50 | MP0008995_early_reproductive_senescence | 1.21709076 |
| 51 | MP0003186_abnormal_redox_activity | 1.21548291 |
| 52 | MP0005253_abnormal_eye_physiology | 1.21309277 |
| 53 | MP0003136_yellow_coat_color | 1.19595360 |
| 54 | MP0004145_abnormal_muscle_electrophysio | 1.15833533 |
| 55 | MP0005000_abnormal_immune_tolerance | 1.14676407 |
| 56 | MP0005408_hypopigmentation | 1.09186719 |
| 57 | MP0001919_abnormal_reproductive_system | 1.08626571 |
| 58 | MP0002166_altered_tumor_susceptibility | 1.06862940 |
| 59 | MP0005645_abnormal_hypothalamus_physiol | 1.06502534 |
| 60 | MP0003763_abnormal_thymus_physiology | 1.04692481 |
| 61 | MP0001853_heart_inflammation | 1.04391042 |
| 62 | MP0009764_decreased_sensitivity_to | 1.03959659 |
| 63 | MP0001984_abnormal_olfaction | 1.02718776 |
| 64 | MP0002723_abnormal_immune_serum | 1.02352884 |
| 65 | MP0000465_gastrointestinal_hemorrhage | 1.02164578 |
| 66 | MP0003011_delayed_dark_adaptation | 1.01234855 |
| 67 | MP0004885_abnormal_endolymph | 0.99166982 |
| 68 | MP0005377_hearing/vestibular/ear_phenot | 0.98216247 |
| 69 | MP0003878_abnormal_ear_physiology | 0.98216247 |
| 70 | MP0001119_abnormal_female_reproductive | 0.96161767 |
| 71 | MP0002452_abnormal_antigen_presenting | 0.95544758 |
| 72 | MP0003567_abnormal_fetal_cardiomyocyte | 0.95033847 |
| 73 | MP0000689_abnormal_spleen_morphology | 0.93655685 |
| 74 | MP0003787_abnormal_imprinting | 0.93622015 |
| 75 | MP0002420_abnormal_adaptive_immunity | 0.93502094 |
| 76 | MP0001529_abnormal_vocalization | 0.93379011 |
| 77 | MP0001819_abnormal_immune_cell | 0.92600368 |
| 78 | MP0005379_endocrine/exocrine_gland_phen | 0.91678121 |
| 79 | MP0004142_abnormal_muscle_tone | 0.91570412 |
| 80 | MP0003077_abnormal_cell_cycle | 0.90997390 |
| 81 | MP0001188_hyperpigmentation | 0.90372768 |
| 82 | MP0003866_abnormal_defecation | 0.88199883 |
| 83 | MP0000383_abnormal_hair_follicle | 0.86569546 |
| 84 | MP0005310_abnormal_salivary_gland | 0.86030612 |
| 85 | MP0004782_abnormal_surfactant_physiolog | 0.84985478 |
| 86 | MP0002398_abnormal_bone_marrow | 0.82699690 |
| 87 | MP0000427_abnormal_hair_cycle | 0.81069135 |
| 88 | MP0002210_abnormal_sex_determination | 0.80611056 |
| 89 | MP0001905_abnormal_dopamine_level | 0.80073001 |
| 90 | MP0004215_abnormal_myocardial_fiber | 0.79661274 |
| 91 | MP0000703_abnormal_thymus_morphology | 0.78841754 |
| 92 | MP0010307_abnormal_tumor_latency | 0.78630922 |
| 93 | MP0001929_abnormal_gametogenesis | 0.77198286 |
| 94 | MP0003724_increased_susceptibility_to | 0.77008112 |
| 95 | MP0005636_abnormal_mineral_homeostasis | 0.76500787 |
| 96 | MP0005085_abnormal_gallbladder_physiolo | 0.75979481 |
| 97 | MP0005332_abnormal_amino_acid | 0.75057077 |
| 98 | MP0001485_abnormal_pinna_reflex | 0.74604188 |
| 99 | MP0003111_abnormal_nucleus_morphology | 0.74556720 |
| 100 | MP0000716_abnormal_immune_system | 0.74203011 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Stomatitis (HP:0010280) | 4.57645176 |
| 2 | Increased CSF lactate (HP:0002490) | 4.07074277 |
| 3 | Mitochondrial inheritance (HP:0001427) | 4.03364341 |
| 4 | Acute necrotizing encephalopathy (HP:0006965) | 4.01205162 |
| 5 | Lipid accumulation in hepatocytes (HP:0006561) | 3.82264813 |
| 6 | Increased hepatocellular lipid droplets (HP:0006565) | 3.70249575 |
| 7 | IgG deficiency (HP:0004315) | 3.64672653 |
| 8 | Acute encephalopathy (HP:0006846) | 3.64637749 |
| 9 | Hepatocellular necrosis (HP:0001404) | 3.64585990 |
| 10 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.42881328 |
| 11 | Progressive macrocephaly (HP:0004481) | 3.42495921 |
| 12 | Hepatic necrosis (HP:0002605) | 3.36914075 |
| 13 | Abnormality of alanine metabolism (HP:0010916) | 3.21750710 |
| 14 | Hyperalaninemia (HP:0003348) | 3.21750710 |
| 15 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.21750710 |
| 16 | Increased serum lactate (HP:0002151) | 3.05213170 |
| 17 | 3-Methylglutaconic aciduria (HP:0003535) | 2.98778999 |
| 18 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.84420260 |
| 19 | Methylmalonic acidemia (HP:0002912) | 2.74782564 |
| 20 | Pancreatic cysts (HP:0001737) | 2.74455050 |
| 21 | Cerebral edema (HP:0002181) | 2.69216242 |
| 22 | Lactic acidosis (HP:0003128) | 2.68672664 |
| 23 | Congenital stationary night blindness (HP:0007642) | 2.64922541 |
| 24 | Renal Fanconi syndrome (HP:0001994) | 2.52210606 |
| 25 | Optic disc pallor (HP:0000543) | 2.51965812 |
| 26 | Nephronophthisis (HP:0000090) | 2.50660049 |
| 27 | Congenital, generalized hypertrichosis (HP:0004540) | 2.48465584 |
| 28 | Methylmalonic aciduria (HP:0012120) | 2.45745381 |
| 29 | Supernumerary spleens (HP:0009799) | 2.44443401 |
| 30 | Exertional dyspnea (HP:0002875) | 2.43352721 |
| 31 | Increased intramyocellular lipid droplets (HP:0012240) | 2.39489375 |
| 32 | Abolished electroretinogram (ERG) (HP:0000550) | 2.33533514 |
| 33 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.32583674 |
| 34 | Abnormality of B cell number (HP:0010975) | 2.31164041 |
| 35 | Respiratory failure (HP:0002878) | 2.31115459 |
| 36 | Type I transferrin isoform profile (HP:0003642) | 2.28941727 |
| 37 | Lethargy (HP:0001254) | 2.25381756 |
| 38 | Molar tooth sign on MRI (HP:0002419) | 2.24065631 |
| 39 | Abnormality of midbrain morphology (HP:0002418) | 2.24065631 |
| 40 | CNS demyelination (HP:0007305) | 2.22595056 |
| 41 | Abnormality of the pons (HP:0007361) | 2.21763502 |
| 42 | B lymphocytopenia (HP:0010976) | 2.19982632 |
| 43 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.19103147 |
| 44 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.19103147 |
| 45 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.16741194 |
| 46 | Increased muscle lipid content (HP:0009058) | 2.16524243 |
| 47 | Abnormality of T cells (HP:0002843) | 2.15626681 |
| 48 | Abnormality of the labia minora (HP:0012880) | 2.14264425 |
| 49 | Duplicated collecting system (HP:0000081) | 2.14215766 |
| 50 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.14081826 |
| 51 | True hermaphroditism (HP:0010459) | 2.13699498 |
| 52 | Colon cancer (HP:0003003) | 2.13433507 |
| 53 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.12653060 |
| 54 | Hyperglycinuria (HP:0003108) | 2.12515403 |
| 55 | Abnormality of T cell physiology (HP:0011840) | 2.12106515 |
| 56 | Pancreatic fibrosis (HP:0100732) | 2.12015011 |
| 57 | Abnormality of urine glucose concentration (HP:0011016) | 2.09719675 |
| 58 | Glycosuria (HP:0003076) | 2.09719675 |
| 59 | Hypoproteinemia (HP:0003075) | 2.09142522 |
| 60 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.06265408 |
| 61 | Hypoplasia of the fovea (HP:0007750) | 2.06265408 |
| 62 | Constricted visual fields (HP:0001133) | 2.06102862 |
| 63 | Severe combined immunodeficiency (HP:0004430) | 2.03087730 |
| 64 | Abnormality of the renal collecting system (HP:0004742) | 2.03066471 |
| 65 | Abnormality of the ileum (HP:0001549) | 2.02774318 |
| 66 | Respiratory difficulties (HP:0002880) | 2.02713372 |
| 67 | Type 2 muscle fiber atrophy (HP:0003554) | 2.02571293 |
| 68 | Pancytopenia (HP:0001876) | 1.99555727 |
| 69 | Leukodystrophy (HP:0002415) | 1.98414515 |
| 70 | Abnormality of serum amino acid levels (HP:0003112) | 1.97333040 |
| 71 | Meckel diverticulum (HP:0002245) | 1.96540546 |
| 72 | Increased IgM level (HP:0003496) | 1.94903779 |
| 73 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.94531162 |
| 74 | Exercise intolerance (HP:0003546) | 1.93959016 |
| 75 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.93311620 |
| 76 | Hypoplasia of the pons (HP:0012110) | 1.93311435 |
| 77 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.90845983 |
| 78 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.88528413 |
| 79 | Testicular atrophy (HP:0000029) | 1.88433202 |
| 80 | Reduced antithrombin III activity (HP:0001976) | 1.88305094 |
| 81 | Thyroiditis (HP:0100646) | 1.87668095 |
| 82 | Abnormality of the renal medulla (HP:0100957) | 1.87503298 |
| 83 | Abnormality of the prostate (HP:0008775) | 1.86722687 |
| 84 | Abnormal biliary tract physiology (HP:0012439) | 1.84419142 |
| 85 | Bile duct proliferation (HP:0001408) | 1.84419142 |
| 86 | Large for gestational age (HP:0001520) | 1.84239994 |
| 87 | Increased serum pyruvate (HP:0003542) | 1.83441594 |
| 88 | Attenuation of retinal blood vessels (HP:0007843) | 1.81986606 |
| 89 | Abnormality of T cell number (HP:0011839) | 1.81589107 |
| 90 | Abnormal spermatogenesis (HP:0008669) | 1.81514119 |
| 91 | T lymphocytopenia (HP:0005403) | 1.81455066 |
| 92 | Abnormal protein glycosylation (HP:0012346) | 1.80192062 |
| 93 | Abnormal glycosylation (HP:0012345) | 1.80192062 |
| 94 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.80192062 |
| 95 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.80192062 |
| 96 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.79925395 |
| 97 | Chromsome breakage (HP:0040012) | 1.79449226 |
| 98 | Hyperglycinemia (HP:0002154) | 1.73296192 |
| 99 | Abnormality of macular pigmentation (HP:0008002) | 1.72589209 |
| 100 | IgM deficiency (HP:0002850) | 1.72539221 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 3.51930344 |
| 2 | VRK2 | 3.06409103 |
| 3 | NUAK1 | 3.00352230 |
| 4 | ZAK | 2.96668653 |
| 5 | EIF2AK3 | 2.96616458 |
| 6 | MST4 | 2.87859742 |
| 7 | TSSK6 | 2.75686862 |
| 8 | TRIM28 | 2.61361491 |
| 9 | BUB1 | 2.40422592 |
| 10 | PBK | 2.34564924 |
| 11 | EIF2AK1 | 2.32193649 |
| 12 | TLK1 | 2.29675575 |
| 13 | NME1 | 2.25088621 |
| 14 | ADRBK2 | 2.22774289 |
| 15 | MKNK2 | 2.11428703 |
| 16 | GRK1 | 2.07466210 |
| 17 | PLK3 | 1.95504273 |
| 18 | FRK | 1.85002981 |
| 19 | STK39 | 1.83403032 |
| 20 | MKNK1 | 1.81694072 |
| 21 | SRPK1 | 1.73088282 |
| 22 | STK16 | 1.69221014 |
| 23 | VRK1 | 1.63787822 |
| 24 | EIF2AK2 | 1.61193134 |
| 25 | OXSR1 | 1.60679551 |
| 26 | PLK4 | 1.45223115 |
| 27 | WNK4 | 1.35332435 |
| 28 | TAOK3 | 1.33985980 |
| 29 | BCKDK | 1.32178522 |
| 30 | MAP4K2 | 1.29087228 |
| 31 | TAF1 | 1.26244833 |
| 32 | NEK1 | 1.24752576 |
| 33 | SCYL2 | 1.24435795 |
| 34 | ACVR1B | 1.20538285 |
| 35 | MAP3K12 | 1.16044049 |
| 36 | TEC | 1.12979569 |
| 37 | WNK3 | 1.08765450 |
| 38 | BMPR1B | 1.04507856 |
| 39 | PLK2 | 1.03967670 |
| 40 | BMPR2 | 1.03305394 |
| 41 | ERBB3 | 1.01153961 |
| 42 | PASK | 0.96677527 |
| 43 | KIT | 0.93403787 |
| 44 | IKBKB | 0.92756708 |
| 45 | PDK2 | 0.91430982 |
| 46 | TNIK | 0.90842992 |
| 47 | CSNK1G3 | 0.88378284 |
| 48 | ALK | 0.88208000 |
| 49 | CSNK1G1 | 0.86315399 |
| 50 | DAPK1 | 0.86173390 |
| 51 | CSNK1A1L | 0.83521072 |
| 52 | BRSK2 | 0.81149523 |
| 53 | DAPK2 | 0.76686384 |
| 54 | PLK1 | 0.71875943 |
| 55 | ITK | 0.71840379 |
| 56 | PINK1 | 0.71499795 |
| 57 | WEE1 | 0.68339491 |
| 58 | BCR | 0.67845130 |
| 59 | PHKG1 | 0.66279426 |
| 60 | PHKG2 | 0.66279426 |
| 61 | ATR | 0.65394261 |
| 62 | TTK | 0.64001720 |
| 63 | MAP2K6 | 0.63268286 |
| 64 | INSRR | 0.61128404 |
| 65 | TIE1 | 0.56712235 |
| 66 | CDC7 | 0.56377428 |
| 67 | CSNK1G2 | 0.55068792 |
| 68 | RPS6KA5 | 0.51644124 |
| 69 | CAMKK2 | 0.51124982 |
| 70 | STK38L | 0.49060740 |
| 71 | PRKCG | 0.48406553 |
| 72 | MYLK | 0.47401404 |
| 73 | MAP4K1 | 0.47027844 |
| 74 | FES | 0.46151809 |
| 75 | MAP3K14 | 0.45664931 |
| 76 | NLK | 0.45505807 |
| 77 | PRKCE | 0.45239689 |
| 78 | CCNB1 | 0.44801346 |
| 79 | AURKB | 0.44701588 |
| 80 | PRKCI | 0.43706228 |
| 81 | CSNK2A1 | 0.43153085 |
| 82 | MAP3K4 | 0.42346199 |
| 83 | PRKCQ | 0.42241088 |
| 84 | MAPKAPK3 | 0.41258373 |
| 85 | LCK | 0.41164584 |
| 86 | IKBKE | 0.39878393 |
| 87 | CSNK2A2 | 0.39108067 |
| 88 | DYRK2 | 0.38677394 |
| 89 | GRK5 | 0.38562295 |
| 90 | FLT3 | 0.36549761 |
| 91 | GRK6 | 0.36466043 |
| 92 | SYK | 0.36243570 |
| 93 | ADRBK1 | 0.35879553 |
| 94 | CDK3 | 0.34999941 |
| 95 | IGF1R | 0.34892449 |
| 96 | TGFBR1 | 0.32088366 |
| 97 | NME2 | 0.30238449 |
| 98 | STK3 | 0.28053136 |
| 99 | ATM | 0.27470524 |
| 100 | LYN | 0.25452813 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.92933696 |
| 2 | Asthma_Homo sapiens_hsa05310 | 2.96450741 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.94406298 |
| 4 | Protein export_Homo sapiens_hsa03060 | 2.90737404 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 2.63033065 |
| 6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.56517455 |
| 7 | Parkinsons disease_Homo sapiens_hsa05012 | 2.40527321 |
| 8 | Allograft rejection_Homo sapiens_hsa05330 | 2.31807163 |
| 9 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.24508870 |
| 10 | Ribosome_Homo sapiens_hsa03010 | 2.16587760 |
| 11 | Homologous recombination_Homo sapiens_hsa03440 | 2.10151516 |
| 12 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.08630859 |
| 13 | Mismatch repair_Homo sapiens_hsa03430 | 1.99978537 |
| 14 | DNA replication_Homo sapiens_hsa03030 | 1.91792218 |
| 15 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.87634439 |
| 16 | RNA degradation_Homo sapiens_hsa03018 | 1.86504194 |
| 17 | Basal transcription factors_Homo sapiens_hsa03022 | 1.85953847 |
| 18 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.85587424 |
| 19 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.77321289 |
| 20 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.75374858 |
| 21 | RNA transport_Homo sapiens_hsa03013 | 1.63366886 |
| 22 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.62991686 |
| 23 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.60822634 |
| 24 | Huntingtons disease_Homo sapiens_hsa05016 | 1.55486595 |
| 25 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.52544945 |
| 26 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.46659909 |
| 27 | Alzheimers disease_Homo sapiens_hsa05010 | 1.43044210 |
| 28 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.39436609 |
| 29 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.37286663 |
| 30 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.36798222 |
| 31 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.36387950 |
| 32 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.30537964 |
| 33 | Base excision repair_Homo sapiens_hsa03410 | 1.29619855 |
| 34 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.28350888 |
| 35 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.27631409 |
| 36 | Spliceosome_Homo sapiens_hsa03040 | 1.27032791 |
| 37 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.23654845 |
| 38 | Purine metabolism_Homo sapiens_hsa00230 | 1.23417822 |
| 39 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.17790631 |
| 40 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.17328104 |
| 41 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.13004950 |
| 42 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.12109700 |
| 43 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.12089280 |
| 44 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.09354274 |
| 45 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.04272280 |
| 46 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.02981484 |
| 47 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.01482119 |
| 48 | Phototransduction_Homo sapiens_hsa04744 | 0.98988293 |
| 49 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.95778665 |
| 50 | Peroxisome_Homo sapiens_hsa04146 | 0.94014600 |
| 51 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.92278125 |
| 52 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.87435375 |
| 53 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.81287005 |
| 54 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.80775364 |
| 55 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.74718032 |
| 56 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.71403519 |
| 57 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.70316318 |
| 58 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.69021207 |
| 59 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.68355314 |
| 60 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.68121373 |
| 61 | Metabolic pathways_Homo sapiens_hsa01100 | 0.62600570 |
| 62 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.62480050 |
| 63 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.61654049 |
| 64 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.61205980 |
| 65 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.61076383 |
| 66 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.60103372 |
| 67 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.57567289 |
| 68 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.56849284 |
| 69 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.56718989 |
| 70 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.55295871 |
| 71 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.54890715 |
| 72 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.54643096 |
| 73 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.53973824 |
| 74 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.53032667 |
| 75 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.52950013 |
| 76 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.52441550 |
| 77 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.52256234 |
| 78 | Retinol metabolism_Homo sapiens_hsa00830 | 0.50079242 |
| 79 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.49792194 |
| 80 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.49093221 |
| 81 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.48024708 |
| 82 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.45987996 |
| 83 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.44841328 |
| 84 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.44340007 |
| 85 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.42968770 |
| 86 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.42936836 |
| 87 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.41803110 |
| 88 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.41670056 |
| 89 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.38540157 |
| 90 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.38108738 |
| 91 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.37924421 |
| 92 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.37381667 |
| 93 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.35721347 |
| 94 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.34265932 |
| 95 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.31994246 |
| 96 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.31945921 |
| 97 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.30720336 |
| 98 | Measles_Homo sapiens_hsa05162 | 0.30549643 |
| 99 | Olfactory transduction_Homo sapiens_hsa04740 | 0.28230397 |
| 100 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.25532121 |

