

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 8.48277877 |
| 2 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 7.32626201 |
| 3 | regulation of isotype switching to IgG isotypes (GO:0048302) | 6.45536524 |
| 4 | positive regulation of interleukin-17 production (GO:0032740) | 6.33670176 |
| 5 | regulation of immunoglobulin secretion (GO:0051023) | 6.11983952 |
| 6 | DNA deamination (GO:0045006) | 5.65558282 |
| 7 | regulation of regulatory T cell differentiation (GO:0045589) | 5.22578145 |
| 8 | positive regulation of isotype switching (GO:0045830) | 5.16852693 |
| 9 | positive regulation of DNA recombination (GO:0045911) | 4.66858286 |
| 10 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.66845183 |
| 11 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.54205054 |
| 12 | cellular response to interleukin-15 (GO:0071350) | 4.38576849 |
| 13 | proteasome assembly (GO:0043248) | 4.21033719 |
| 14 | positive regulation of immunoglobulin production (GO:0002639) | 4.03663927 |
| 15 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 3.97611496 |
| 16 | positive regulation of activated T cell proliferation (GO:0042104) | 3.97517217 |
| 17 | interferon-gamma production (GO:0032609) | 3.91761646 |
| 18 | negative regulation of B cell apoptotic process (GO:0002903) | 3.87043015 |
| 19 | termination of RNA polymerase I transcription (GO:0006363) | 3.86746767 |
| 20 | positive regulation of T-helper 1 type immune response (GO:0002827) | 3.81682834 |
| 21 | regulation of podosome assembly (GO:0071801) | 3.81174133 |
| 22 | cytidine deamination (GO:0009972) | 3.80713861 |
| 23 | cytidine metabolic process (GO:0046087) | 3.80713861 |
| 24 | cytidine catabolic process (GO:0006216) | 3.80713861 |
| 25 | maturation of 5.8S rRNA (GO:0000460) | 3.80440790 |
| 26 | pseudouridine synthesis (GO:0001522) | 3.75939827 |
| 27 | regulation of chronic inflammatory response (GO:0002676) | 3.73573634 |
| 28 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.66204888 |
| 29 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 3.65895052 |
| 30 | positive regulation of B cell mediated immunity (GO:0002714) | 3.65895052 |
| 31 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 3.64924862 |
| 32 | T-helper cell differentiation (GO:0042093) | 3.64924862 |
| 33 | L-fucose catabolic process (GO:0042355) | 3.54063744 |
| 34 | fucose catabolic process (GO:0019317) | 3.54063744 |
| 35 | L-fucose metabolic process (GO:0042354) | 3.54063744 |
| 36 | positive regulation of tyrosine phosphorylation of STAT protein (GO:0042531) | 3.50889655 |
| 37 | otic vesicle formation (GO:0030916) | 3.50650387 |
| 38 | positive regulation of defense response to virus by host (GO:0002230) | 3.46654952 |
| 39 | T cell differentiation involved in immune response (GO:0002292) | 3.44546540 |
| 40 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 3.44546540 |
| 41 | alpha-beta T cell activation involved in immune response (GO:0002287) | 3.44546540 |
| 42 | response to interleukin-15 (GO:0070672) | 3.42631545 |
| 43 | rRNA methylation (GO:0031167) | 3.41939909 |
| 44 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 3.40289714 |
| 45 | regulation of memory T cell differentiation (GO:0043380) | 3.38656734 |
| 46 | rRNA modification (GO:0000154) | 3.37390114 |
| 47 | chaperone-mediated protein transport (GO:0072321) | 3.33568174 |
| 48 | regulation of interleukin-17 production (GO:0032660) | 3.29465522 |
| 49 | rRNA processing (GO:0006364) | 3.28393864 |
| 50 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.27074786 |
| 51 | positive regulation of JAK-STAT cascade (GO:0046427) | 3.25498654 |
| 52 | positive regulation of cell fate commitment (GO:0010455) | 3.24449656 |
| 53 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.23494596 |
| 54 | peptidyl-histidine modification (GO:0018202) | 3.17146013 |
| 55 | rRNA metabolic process (GO:0016072) | 3.16007705 |
| 56 | transcription initiation from RNA polymerase I promoter (GO:0006361) | 3.12893231 |
| 57 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.12463303 |
| 58 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.12463303 |
| 59 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.10803106 |
| 60 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.10803106 |
| 61 | regulation of isotype switching (GO:0045191) | 3.05062940 |
| 62 | ribosome assembly (GO:0042255) | 3.04634782 |
| 63 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.03661908 |
| 64 | negative regulation of telomere maintenance (GO:0032205) | 3.03044969 |
| 65 | DNA double-strand break processing (GO:0000729) | 3.01693499 |
| 66 | transcription from RNA polymerase I promoter (GO:0006360) | 3.00500904 |
| 67 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.95318409 |
| 68 | ATP synthesis coupled proton transport (GO:0015986) | 2.95318409 |
| 69 | platelet dense granule organization (GO:0060155) | 2.94481602 |
| 70 | respiratory chain complex IV assembly (GO:0008535) | 2.94052857 |
| 71 | pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174) | 2.93718292 |
| 72 | UMP metabolic process (GO:0046049) | 2.93718292 |
| 73 | pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173) | 2.93718292 |
| 74 | UMP biosynthetic process (GO:0006222) | 2.93718292 |
| 75 | regulation of tyrosine phosphorylation of STAT protein (GO:0042509) | 2.93415846 |
| 76 | regulation of immunoglobulin production (GO:0002637) | 2.91663887 |
| 77 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.91650946 |
| 78 | regulation of tyrosine phosphorylation of Stat1 protein (GO:0042510) | 2.87597743 |
| 79 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.85650343 |
| 80 | transcription from mitochondrial promoter (GO:0006390) | 2.81609849 |
| 81 | regulation of activated T cell proliferation (GO:0046006) | 2.81513797 |
| 82 | behavioral response to nicotine (GO:0035095) | 2.79895534 |
| 83 | regulation of T-helper 1 type immune response (GO:0002825) | 2.79003563 |
| 84 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.78974273 |
| 85 | mitochondrial RNA metabolic process (GO:0000959) | 2.78572247 |
| 86 | alpha-beta T cell differentiation (GO:0046632) | 2.75101506 |
| 87 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.74207924 |
| 88 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.73335580 |
| 89 | pyrimidine ribonucleoside biosynthetic process (GO:0046132) | 2.73040432 |
| 90 | ribosome biogenesis (GO:0042254) | 2.72922214 |
| 91 | CD4-positive, alpha-beta T cell differentiation (GO:0043367) | 2.72277688 |
| 92 | pyrimidine ribonucleoside metabolic process (GO:0046131) | 2.72040477 |
| 93 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 2.70805348 |
| 94 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.69622451 |
| 95 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.69622451 |
| 96 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.69622451 |
| 97 | telomere maintenance via telomerase (GO:0007004) | 2.66926119 |
| 98 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.66209192 |
| 99 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.66181423 |
| 100 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.66181423 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.52811440 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.98195262 |
| 3 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 3.64654839 |
| 4 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 3.17323934 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.14728935 |
| 6 | VDR_22108803_ChIP-Seq_LS180_Human | 3.07238317 |
| 7 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.81038627 |
| 8 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.69636988 |
| 9 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.57021026 |
| 10 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.53064752 |
| 11 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.52382082 |
| 12 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.46706952 |
| 13 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.46177735 |
| 14 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.40802618 |
| 15 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.33293942 |
| 16 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.28675865 |
| 17 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.28501801 |
| 18 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.27270287 |
| 19 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 2.19463414 |
| 20 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.10808964 |
| 21 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.04133998 |
| 22 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.97949705 |
| 23 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.97866637 |
| 24 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.96637053 |
| 25 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.91981305 |
| 26 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.90080706 |
| 27 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.89956912 |
| 28 | EWS_26573619_Chip-Seq_HEK293_Human | 1.87374174 |
| 29 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.83004616 |
| 30 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.77103756 |
| 31 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.73109603 |
| 32 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.63921196 |
| 33 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.63357839 |
| 34 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.63236040 |
| 35 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.61527667 |
| 36 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.59260358 |
| 37 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.57500178 |
| 38 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.52381238 |
| 39 | FUS_26573619_Chip-Seq_HEK293_Human | 1.50959062 |
| 40 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.49540226 |
| 41 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.49426804 |
| 42 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.49297714 |
| 43 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.47622919 |
| 44 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.46829408 |
| 45 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.46829408 |
| 46 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.45420171 |
| 47 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.43238838 |
| 48 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.39698051 |
| 49 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.39694821 |
| 50 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.36569242 |
| 51 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.36467191 |
| 52 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.33758890 |
| 53 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.32802686 |
| 54 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.30378289 |
| 55 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.28756707 |
| 56 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.26732921 |
| 57 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.25249375 |
| 58 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.24904091 |
| 59 | P300_19829295_ChIP-Seq_ESCs_Human | 1.23934196 |
| 60 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.20945497 |
| 61 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.20511810 |
| 62 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.19554823 |
| 63 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.18931826 |
| 64 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.15258394 |
| 65 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.14597928 |
| 66 | GATA3_26560356_Chip-Seq_TH2_Human | 1.13518173 |
| 67 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.13281382 |
| 68 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.11253843 |
| 69 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.10943420 |
| 70 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.10249485 |
| 71 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.09579562 |
| 72 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.08873335 |
| 73 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.05527289 |
| 74 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.04619957 |
| 75 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.02399374 |
| 76 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.02188938 |
| 77 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.01678682 |
| 78 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.01382709 |
| 79 | AR_20517297_ChIP-Seq_VCAP_Human | 1.01141095 |
| 80 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.00696889 |
| 81 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.00696889 |
| 82 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.98247517 |
| 83 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.97935903 |
| 84 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.96263856 |
| 85 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.95963283 |
| 86 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.95319582 |
| 87 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.94972970 |
| 88 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 0.94118670 |
| 89 | NCOR_22424771_ChIP-Seq_293T_Human | 0.94034404 |
| 90 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.93547487 |
| 91 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.93276191 |
| 92 | GATA1_22025678_ChIP-Seq_K562_Human | 0.92651817 |
| 93 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.92396835 |
| 94 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.92381242 |
| 95 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.92295017 |
| 96 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.92295017 |
| 97 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.92036371 |
| 98 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.91756594 |
| 99 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 0.91527214 |
| 100 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.91525442 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001835_abnormal_antigen_presentation | 3.94345640 |
| 2 | MP0000566_synostosis | 3.65453658 |
| 3 | MP0005084_abnormal_gallbladder_morpholo | 2.98932282 |
| 4 | MP0005670_abnormal_white_adipose | 2.90419263 |
| 5 | MP0001853_heart_inflammation | 2.71227539 |
| 6 | MP0003136_yellow_coat_color | 2.49199007 |
| 7 | MP0003300_gastrointestinal_ulcer | 2.43828766 |
| 8 | MP0000465_gastrointestinal_hemorrhage | 2.38296951 |
| 9 | MP0006292_abnormal_olfactory_placode | 2.27778301 |
| 10 | MP0008877_abnormal_DNA_methylation | 2.18417123 |
| 11 | MP0001873_stomach_inflammation | 2.17325811 |
| 12 | MP0002138_abnormal_hepatobiliary_system | 2.16276503 |
| 13 | MP0003878_abnormal_ear_physiology | 2.15576225 |
| 14 | MP0005377_hearing/vestibular/ear_phenot | 2.15576225 |
| 15 | MP0005387_immune_system_phenotype | 2.03267678 |
| 16 | MP0001790_abnormal_immune_system | 2.03267678 |
| 17 | MP0008872_abnormal_physiological_respon | 1.91022659 |
| 18 | MP0003786_premature_aging | 1.88712899 |
| 19 | MP0005645_abnormal_hypothalamus_physiol | 1.87326751 |
| 20 | MP0004381_abnormal_hair_follicle | 1.82823396 |
| 21 | MP0005671_abnormal_response_to | 1.79746690 |
| 22 | MP0003567_abnormal_fetal_cardiomyocyte | 1.79292539 |
| 23 | MP0009785_altered_susceptibility_to | 1.78780444 |
| 24 | MP0002166_altered_tumor_susceptibility | 1.77197773 |
| 25 | MP0000685_abnormal_immune_system | 1.75320661 |
| 26 | MP0002148_abnormal_hypersensitivity_rea | 1.68093352 |
| 27 | MP0000604_amyloidosis | 1.65153670 |
| 28 | MP0001502_abnormal_circadian_rhythm | 1.64342922 |
| 29 | MP0001800_abnormal_humoral_immune | 1.63801224 |
| 30 | MP0001661_extended_life_span | 1.63327225 |
| 31 | MP0006072_abnormal_retinal_apoptosis | 1.60112998 |
| 32 | MP0002102_abnormal_ear_morphology | 1.58606760 |
| 33 | MP0002006_tumorigenesis | 1.56059827 |
| 34 | MP0009333_abnormal_splenocyte_physiolog | 1.53422357 |
| 35 | MP0003718_maternal_effect | 1.46088809 |
| 36 | MP0000372_irregular_coat_pigmentation | 1.46084584 |
| 37 | MP0008058_abnormal_DNA_repair | 1.45455764 |
| 38 | MP0001986_abnormal_taste_sensitivity | 1.42909674 |
| 39 | MP0005085_abnormal_gallbladder_physiolo | 1.40034225 |
| 40 | MP0000427_abnormal_hair_cycle | 1.40024082 |
| 41 | MP0003646_muscle_fatigue | 1.37296494 |
| 42 | MP0005310_abnormal_salivary_gland | 1.36580863 |
| 43 | MP0004957_abnormal_blastocyst_morpholog | 1.33058235 |
| 44 | MP0003950_abnormal_plasma_membrane | 1.30525884 |
| 45 | MP0003195_calcinosis | 1.29291658 |
| 46 | MP0004142_abnormal_muscle_tone | 1.28876432 |
| 47 | MP0000569_abnormal_digit_pigmentation | 1.28666836 |
| 48 | MP0008875_abnormal_xenobiotic_pharmacok | 1.23937933 |
| 49 | MP0001501_abnormal_sleep_pattern | 1.22272565 |
| 50 | MP0002938_white_spotting | 1.21662610 |
| 51 | MP0005551_abnormal_eye_electrophysiolog | 1.20969591 |
| 52 | MP0005000_abnormal_immune_tolerance | 1.20476899 |
| 53 | MP0002277_abnormal_respiratory_mucosa | 1.18519853 |
| 54 | MP0001958_emphysema | 1.16937000 |
| 55 | MP0001529_abnormal_vocalization | 1.15160889 |
| 56 | MP0003763_abnormal_thymus_physiology | 1.14592687 |
| 57 | MP0001188_hyperpigmentation | 1.11979124 |
| 58 | MP0001485_abnormal_pinna_reflex | 1.10435623 |
| 59 | MP0002282_abnormal_trachea_morphology | 1.05960569 |
| 60 | MP0001984_abnormal_olfaction | 1.03446262 |
| 61 | MP0005379_endocrine/exocrine_gland_phen | 1.02730860 |
| 62 | MP0002723_abnormal_immune_serum | 1.01954908 |
| 63 | MP0006082_CNS_inflammation | 1.01714811 |
| 64 | MP0003186_abnormal_redox_activity | 0.93694985 |
| 65 | MP0003866_abnormal_defecation | 0.93342605 |
| 66 | MP0005025_abnormal_response_to | 0.93334549 |
| 67 | MP0010329_abnormal_lipoprotein_level | 0.92885642 |
| 68 | MP0001968_abnormal_touch/_nociception | 0.92815364 |
| 69 | MP0002736_abnormal_nociception_after | 0.92058616 |
| 70 | MP0004742_abnormal_vestibular_system | 0.89205265 |
| 71 | MP0003936_abnormal_reproductive_system | 0.89180767 |
| 72 | MP0002272_abnormal_nervous_system | 0.89027137 |
| 73 | MP0002420_abnormal_adaptive_immunity | 0.88771088 |
| 74 | MP0000537_abnormal_urethra_morphology | 0.88747627 |
| 75 | MP0002693_abnormal_pancreas_physiology | 0.88581912 |
| 76 | MP0004885_abnormal_endolymph | 0.88001757 |
| 77 | MP0006035_abnormal_mitochondrial_morpho | 0.87376781 |
| 78 | MP0002405_respiratory_system_inflammati | 0.86891616 |
| 79 | MP0001819_abnormal_immune_cell | 0.84866864 |
| 80 | MP0000371_diluted_coat_color | 0.84056320 |
| 81 | MP0004145_abnormal_muscle_electrophysio | 0.83730028 |
| 82 | MP0005389_reproductive_system_phenotype | 0.83557233 |
| 83 | MP0004134_abnormal_chest_morphology | 0.79665996 |
| 84 | MP0005083_abnormal_biliary_tract | 0.79552746 |
| 85 | MP0000631_abnormal_neuroendocrine_gland | 0.78849829 |
| 86 | MP0003787_abnormal_imprinting | 0.78800438 |
| 87 | MP0001845_abnormal_inflammatory_respons | 0.78171468 |
| 88 | MP0010155_abnormal_intestine_physiology | 0.77617968 |
| 89 | MP0001919_abnormal_reproductive_system | 0.77381854 |
| 90 | MP0005636_abnormal_mineral_homeostasis | 0.76631856 |
| 91 | MP0005332_abnormal_amino_acid | 0.74766778 |
| 92 | MP0000689_abnormal_spleen_morphology | 0.74282207 |
| 93 | MP0002452_abnormal_antigen_presenting | 0.73951281 |
| 94 | MP0005386_behavior/neurological_phenoty | 0.71685156 |
| 95 | MP0004924_abnormal_behavior | 0.71685156 |
| 96 | MP0002398_abnormal_bone_marrow | 0.71477338 |
| 97 | MP0003252_abnormal_bile_duct | 0.70428638 |
| 98 | MP0005075_abnormal_melanosome_morpholog | 0.68300075 |
| 99 | MP0006036_abnormal_mitochondrial_physio | 0.65947957 |
| 100 | MP0001881_abnormal_mammary_gland | 0.65291917 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of the pons (HP:0007361) | 4.62612035 |
| 2 | Stomatitis (HP:0010280) | 4.12115028 |
| 3 | Abnormality of the labia minora (HP:0012880) | 3.79594483 |
| 4 | Oral leukoplakia (HP:0002745) | 3.63961035 |
| 5 | Hypoplasia of the pons (HP:0012110) | 3.51326715 |
| 6 | Increased hepatocellular lipid droplets (HP:0006565) | 3.36572534 |
| 7 | Large for gestational age (HP:0001520) | 3.23394579 |
| 8 | Conical tooth (HP:0000698) | 3.14548668 |
| 9 | IgG deficiency (HP:0004315) | 3.14481726 |
| 10 | Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658) | 3.05435092 |
| 11 | Lipid accumulation in hepatocytes (HP:0006561) | 3.01692827 |
| 12 | Megalencephaly (HP:0001355) | 2.94982765 |
| 13 | 3-Methylglutaconic aciduria (HP:0003535) | 2.93424679 |
| 14 | Pancreatic cysts (HP:0001737) | 2.90881463 |
| 15 | Severe combined immunodeficiency (HP:0004430) | 2.87894482 |
| 16 | Aplastic anemia (HP:0001915) | 2.81738501 |
| 17 | Renal Fanconi syndrome (HP:0001994) | 2.76122930 |
| 18 | Supernumerary bones of the axial skeleton (HP:0009144) | 2.75196222 |
| 19 | Acute necrotizing encephalopathy (HP:0006965) | 2.72169146 |
| 20 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.71424866 |
| 21 | Congenital, generalized hypertrichosis (HP:0004540) | 2.70131650 |
| 22 | Lip pit (HP:0100267) | 2.70082276 |
| 23 | Abnormality of midbrain morphology (HP:0002418) | 2.66797533 |
| 24 | Molar tooth sign on MRI (HP:0002419) | 2.66797533 |
| 25 | Thyroiditis (HP:0100646) | 2.61312354 |
| 26 | Increased CSF lactate (HP:0002490) | 2.60813225 |
| 27 | Abnormality of the middle phalanges of the toes (HP:0010183) | 2.59896613 |
| 28 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.59745830 |
| 29 | Short tibia (HP:0005736) | 2.46233680 |
| 30 | Optic neuritis (HP:0100653) | 2.45368786 |
| 31 | Retrobulbar optic neuritis (HP:0100654) | 2.45368786 |
| 32 | Type II lissencephaly (HP:0007260) | 2.44733879 |
| 33 | Mitochondrial inheritance (HP:0001427) | 2.38378976 |
| 34 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.38282741 |
| 35 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 2.37742509 |
| 36 | Hypoplasia of the ulna (HP:0003022) | 2.33786736 |
| 37 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.33572840 |
| 38 | Increased serum lactate (HP:0002151) | 2.32035219 |
| 39 | Abnormal pupillary function (HP:0007686) | 2.30834695 |
| 40 | Acute encephalopathy (HP:0006846) | 2.30583899 |
| 41 | Progressive macrocephaly (HP:0004481) | 2.30149838 |
| 42 | Abnormality of the parietal bone (HP:0002696) | 2.29181334 |
| 43 | Abnormality of methionine metabolism (HP:0010901) | 2.27027772 |
| 44 | Duplicated collecting system (HP:0000081) | 2.25517377 |
| 45 | Cupped ear (HP:0000378) | 2.25209179 |
| 46 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.22788174 |
| 47 | 2-3 toe syndactyly (HP:0004691) | 2.21969375 |
| 48 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.20829838 |
| 49 | Supernumerary ribs (HP:0005815) | 2.19377116 |
| 50 | Recurrent cutaneous fungal infections (HP:0011370) | 2.18433586 |
| 51 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.18433586 |
| 52 | Abnormality of the diencephalon (HP:0010662) | 2.18405468 |
| 53 | Esophageal atresia (HP:0002032) | 2.17228355 |
| 54 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.16142526 |
| 55 | T lymphocytopenia (HP:0005403) | 2.15986834 |
| 56 | Combined immunodeficiency (HP:0005387) | 2.14658578 |
| 57 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.14293531 |
| 58 | Hypoplasia of the radius (HP:0002984) | 2.11999400 |
| 59 | Facial cleft (HP:0002006) | 2.11774781 |
| 60 | Renal cortical cysts (HP:0000803) | 2.10422501 |
| 61 | True hermaphroditism (HP:0010459) | 2.09865654 |
| 62 | Milia (HP:0001056) | 2.08382744 |
| 63 | Nasolacrimal duct obstruction (HP:0000579) | 2.07456470 |
| 64 | Abnormality of the renal collecting system (HP:0004742) | 2.07411371 |
| 65 | Vertebral fusion (HP:0002948) | 2.05852638 |
| 66 | Gastrointestinal atresia (HP:0002589) | 2.05696842 |
| 67 | Pancreatic fibrosis (HP:0100732) | 2.05244261 |
| 68 | Aplasia involving bones of the upper limbs (HP:0009823) | 2.03932281 |
| 69 | Aplasia of the phalanges of the hand (HP:0009802) | 2.03932281 |
| 70 | Aplasia involving bones of the extremities (HP:0009825) | 2.03932281 |
| 71 | Intestinal atresia (HP:0011100) | 2.02535128 |
| 72 | Orchitis (HP:0100796) | 2.02105200 |
| 73 | Short phalanx of the thumb (HP:0009660) | 2.02083348 |
| 74 | Bilateral microphthalmos (HP:0007633) | 2.01200967 |
| 75 | Sparse lateral eyebrow (HP:0005338) | 2.00517693 |
| 76 | Fused cervical vertebrae (HP:0002949) | 1.98277544 |
| 77 | Posterior subcapsular cataract (HP:0007787) | 1.97527914 |
| 78 | Fibular hypoplasia (HP:0003038) | 1.96633453 |
| 79 | Forearm undergrowth (HP:0009821) | 1.96099925 |
| 80 | Aplasia/Hypoplasia of the fibula (HP:0006492) | 1.95622572 |
| 81 | Pendular nystagmus (HP:0012043) | 1.95441862 |
| 82 | Exertional dyspnea (HP:0002875) | 1.94684677 |
| 83 | Partial duplication of thumb phalanx (HP:0009944) | 1.94269515 |
| 84 | Absent radius (HP:0003974) | 1.94070223 |
| 85 | Congenital stationary night blindness (HP:0007642) | 1.93488138 |
| 86 | Brittle hair (HP:0002299) | 1.89322088 |
| 87 | Glossoptosis (HP:0000162) | 1.88271398 |
| 88 | Poor head control (HP:0002421) | 1.85694087 |
| 89 | Abnormality of the lacrimal duct (HP:0011481) | 1.85476936 |
| 90 | Abnormality of T cells (HP:0002843) | 1.84829567 |
| 91 | Short hallux (HP:0010109) | 1.84401603 |
| 92 | Absent forearm bone (HP:0003953) | 1.83904851 |
| 93 | Aplasia involving forearm bones (HP:0009822) | 1.83904851 |
| 94 | Multiple enchondromatosis (HP:0005701) | 1.83806217 |
| 95 | Median cleft lip (HP:0000161) | 1.82195851 |
| 96 | Short thumb (HP:0009778) | 1.80871739 |
| 97 | Abnormality of homocysteine metabolism (HP:0010919) | 1.78450317 |
| 98 | Homocystinuria (HP:0002156) | 1.78450317 |
| 99 | Abnormality of T cell number (HP:0011839) | 1.78426613 |
| 100 | Azoospermia (HP:0000027) | 1.77873657 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TSSK6 | 5.93975161 |
| 2 | MST4 | 4.12684063 |
| 3 | NUAK1 | 3.51925163 |
| 4 | EIF2AK1 | 3.28408813 |
| 5 | TXK | 2.99994258 |
| 6 | SRPK1 | 2.68519212 |
| 7 | NME1 | 2.58390785 |
| 8 | EIF2AK3 | 2.45384800 |
| 9 | PINK1 | 2.19817841 |
| 10 | FGFR2 | 2.18991938 |
| 11 | TLK1 | 2.17477479 |
| 12 | MKNK2 | 2.13712525 |
| 13 | VRK2 | 2.04522587 |
| 14 | TESK1 | 1.96385017 |
| 15 | ADRBK2 | 1.86800398 |
| 16 | FRK | 1.82109929 |
| 17 | ZAK | 1.77888884 |
| 18 | ALK | 1.76477431 |
| 19 | FES | 1.72956788 |
| 20 | PBK | 1.66658549 |
| 21 | EIF2AK2 | 1.60088950 |
| 22 | BUB1 | 1.54882902 |
| 23 | GRK1 | 1.49135623 |
| 24 | INSRR | 1.48203110 |
| 25 | PLK3 | 1.44824147 |
| 26 | MAP2K6 | 1.42993951 |
| 27 | TRIM28 | 1.38065388 |
| 28 | IKBKE | 1.34142566 |
| 29 | SIK3 | 1.30314470 |
| 30 | MAP3K14 | 1.29869576 |
| 31 | WNK4 | 1.29716465 |
| 32 | FGFR3 | 1.26643615 |
| 33 | MKNK1 | 1.20826876 |
| 34 | FGFR1 | 1.19409552 |
| 35 | VRK1 | 1.11842536 |
| 36 | CASK | 1.07502080 |
| 37 | TEC | 1.06951138 |
| 38 | AKT3 | 0.98638412 |
| 39 | TAOK3 | 0.97996717 |
| 40 | NLK | 0.97218096 |
| 41 | NEK1 | 0.96249821 |
| 42 | PASK | 0.90603331 |
| 43 | PIK3CG | 0.88175395 |
| 44 | JAK3 | 0.87843848 |
| 45 | PDK2 | 0.86853331 |
| 46 | IKBKB | 0.78912338 |
| 47 | TAF1 | 0.73636265 |
| 48 | OXSR1 | 0.72586443 |
| 49 | DAPK2 | 0.72174214 |
| 50 | DAPK1 | 0.72136109 |
| 51 | MAPKAPK3 | 0.69541322 |
| 52 | KIT | 0.68226321 |
| 53 | KDR | 0.64428024 |
| 54 | CSK | 0.64411082 |
| 55 | TIE1 | 0.64335132 |
| 56 | STK4 | 0.64025546 |
| 57 | BMPR1B | 0.63856310 |
| 58 | PAK3 | 0.63588059 |
| 59 | ITK | 0.62734332 |
| 60 | TNIK | 0.60478720 |
| 61 | STK39 | 0.58193832 |
| 62 | TAOK1 | 0.55266253 |
| 63 | WNK3 | 0.55119100 |
| 64 | CSNK1G1 | 0.54567891 |
| 65 | PAK4 | 0.52827159 |
| 66 | LATS1 | 0.52223258 |
| 67 | PHKG2 | 0.52172402 |
| 68 | PHKG1 | 0.52172402 |
| 69 | STK3 | 0.51593691 |
| 70 | DYRK2 | 0.50451631 |
| 71 | TGFBR1 | 0.48749118 |
| 72 | MAP4K2 | 0.48663668 |
| 73 | CSNK1A1L | 0.47909625 |
| 74 | JAK1 | 0.46930936 |
| 75 | PRKCQ | 0.45672344 |
| 76 | STK38 | 0.45622562 |
| 77 | MARK3 | 0.43911046 |
| 78 | CSNK1G3 | 0.43908293 |
| 79 | CSNK1E | 0.42248607 |
| 80 | STK38L | 0.39092794 |
| 81 | LCK | 0.38631250 |
| 82 | ACVR1B | 0.37641243 |
| 83 | MAPKAPK2 | 0.36885180 |
| 84 | TNK2 | 0.36443445 |
| 85 | PRKCE | 0.35196835 |
| 86 | ADRBK1 | 0.34958578 |
| 87 | ATR | 0.34528164 |
| 88 | IGF1R | 0.33623116 |
| 89 | CCNB1 | 0.33422813 |
| 90 | WEE1 | 0.33168562 |
| 91 | PLK1 | 0.32943430 |
| 92 | DYRK3 | 0.32811096 |
| 93 | PRKCG | 0.31589505 |
| 94 | TYK2 | 0.30138605 |
| 95 | PLK2 | 0.27333532 |
| 96 | PNCK | 0.27092143 |
| 97 | SGK2 | 0.26663255 |
| 98 | RPS6KA5 | 0.24469150 |
| 99 | CSNK2A1 | 0.23333440 |
| 100 | CSNK2A2 | 0.20194179 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.39827366 |
| 2 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 4.06708075 |
| 3 | Allograft rejection_Homo sapiens_hsa05330 | 3.13084182 |
| 4 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.96037127 |
| 5 | Asthma_Homo sapiens_hsa05310 | 2.75118813 |
| 6 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.68900605 |
| 7 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.43811412 |
| 8 | Basal transcription factors_Homo sapiens_hsa03022 | 2.22994535 |
| 9 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.03378290 |
| 10 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.01121248 |
| 11 | RNA polymerase_Homo sapiens_hsa03020 | 2.00362085 |
| 12 | Protein export_Homo sapiens_hsa03060 | 1.99563986 |
| 13 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.98698900 |
| 14 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.97919458 |
| 15 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.97706526 |
| 16 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.97315151 |
| 17 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.87220127 |
| 18 | Homologous recombination_Homo sapiens_hsa03440 | 1.79567446 |
| 19 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.76752436 |
| 20 | RNA transport_Homo sapiens_hsa03013 | 1.75499351 |
| 21 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.71220475 |
| 22 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.68193787 |
| 23 | RNA degradation_Homo sapiens_hsa03018 | 1.65375411 |
| 24 | Spliceosome_Homo sapiens_hsa03040 | 1.53169076 |
| 25 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.50706640 |
| 26 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.50169366 |
| 27 | Parkinsons disease_Homo sapiens_hsa05012 | 1.42539610 |
| 28 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.36180102 |
| 29 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.36016650 |
| 30 | Peroxisome_Homo sapiens_hsa04146 | 1.34215781 |
| 31 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.33740228 |
| 32 | Ribosome_Homo sapiens_hsa03010 | 1.30632211 |
| 33 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.29877321 |
| 34 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.27913086 |
| 35 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.27854896 |
| 36 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.21737577 |
| 37 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.20710619 |
| 38 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.17637073 |
| 39 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.14538944 |
| 40 | Measles_Homo sapiens_hsa05162 | 1.13401542 |
| 41 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.07901346 |
| 42 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.02568508 |
| 43 | Purine metabolism_Homo sapiens_hsa00230 | 1.02311233 |
| 44 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.02009583 |
| 45 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.97347630 |
| 46 | Circadian rhythm_Homo sapiens_hsa04710 | 0.93405528 |
| 47 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.91192098 |
| 48 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.90757850 |
| 49 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.88344393 |
| 50 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.88336655 |
| 51 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.85641055 |
| 52 | Huntingtons disease_Homo sapiens_hsa05016 | 0.84030049 |
| 53 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.82770565 |
| 54 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.81186690 |
| 55 | Mismatch repair_Homo sapiens_hsa03430 | 0.79402218 |
| 56 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.78874087 |
| 57 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.78200299 |
| 58 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.76720968 |
| 59 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.76122088 |
| 60 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.74461339 |
| 61 | Alzheimers disease_Homo sapiens_hsa05010 | 0.73874569 |
| 62 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.73080731 |
| 63 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.66892186 |
| 64 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.65529528 |
| 65 | Phototransduction_Homo sapiens_hsa04744 | 0.65398047 |
| 66 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.60211106 |
| 67 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.60021531 |
| 68 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.57535847 |
| 69 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.56163367 |
| 70 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.51560430 |
| 71 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.51235744 |
| 72 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.48237502 |
| 73 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.47099181 |
| 74 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.46953027 |
| 75 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.45911610 |
| 76 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.45732755 |
| 77 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.45631203 |
| 78 | Metabolic pathways_Homo sapiens_hsa01100 | 0.44969701 |
| 79 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.44945504 |
| 80 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.44938663 |
| 81 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.43854399 |
| 82 | Retinol metabolism_Homo sapiens_hsa00830 | 0.43650640 |
| 83 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.42483600 |
| 84 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.42458060 |
| 85 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.42137762 |
| 86 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.41809170 |
| 87 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.39752439 |
| 88 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.35372640 |
| 89 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.35146856 |
| 90 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.34662868 |
| 91 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.34617753 |
| 92 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.34453111 |
| 93 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.31626024 |
| 94 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.30615382 |
| 95 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.30210545 |
| 96 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.29957984 |
| 97 | Carbon metabolism_Homo sapiens_hsa01200 | 0.29882358 |
| 98 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.28326733 |
| 99 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.27261091 |
| 100 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.25982720 |

