

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 7.77617542 |
| 2 | cytidine metabolic process (GO:0046087) | 7.76839688 |
| 3 | cytidine catabolic process (GO:0006216) | 7.76839688 |
| 4 | cytidine deamination (GO:0009972) | 7.76839688 |
| 5 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 7.60065309 |
| 6 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 6.63574953 |
| 7 | regulation of regulatory T cell differentiation (GO:0045589) | 5.74291490 |
| 8 | negative regulation by host of viral transcription (GO:0043922) | 4.70771391 |
| 9 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 4.49719835 |
| 10 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.37685816 |
| 11 | regulation of chronic inflammatory response (GO:0002676) | 4.14529314 |
| 12 | negative regulation of T cell apoptotic process (GO:0070233) | 4.02460241 |
| 13 | proteasome assembly (GO:0043248) | 3.97527846 |
| 14 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.86992118 |
| 15 | positive regulation of interleukin-8 secretion (GO:2000484) | 3.78088864 |
| 16 | positive T cell selection (GO:0043368) | 3.74968488 |
| 17 | positive regulation of defense response to virus by host (GO:0002230) | 3.67645327 |
| 18 | cellular response to interleukin-15 (GO:0071350) | 3.67324200 |
| 19 | ribosomal small subunit assembly (GO:0000028) | 3.63790071 |
| 20 | protein neddylation (GO:0045116) | 3.58897204 |
| 21 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.58501836 |
| 22 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.55872790 |
| 23 | positive regulation of interleukin-17 production (GO:0032740) | 3.55321142 |
| 24 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.53273468 |
| 25 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.47852715 |
| 26 | regulation of activation of Janus kinase activity (GO:0010533) | 3.47235610 |
| 27 | positive thymic T cell selection (GO:0045059) | 3.46190636 |
| 28 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.39929197 |
| 29 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.39880565 |
| 30 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.39880565 |
| 31 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.39880565 |
| 32 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.36952049 |
| 33 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.36952049 |
| 34 | negative regulation of lymphocyte apoptotic process (GO:0070229) | 3.36349298 |
| 35 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.35369996 |
| 36 | eosinophil chemotaxis (GO:0048245) | 3.33336189 |
| 37 | regulation of immunoglobulin secretion (GO:0051023) | 3.32045985 |
| 38 | negative regulation of viral genome replication (GO:0045071) | 3.28995910 |
| 39 | T cell migration (GO:0072678) | 3.28215855 |
| 40 | DNA demethylation (GO:0080111) | 3.27901693 |
| 41 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.26265880 |
| 42 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.25878668 |
| 43 | negative regulation of ligase activity (GO:0051352) | 3.25878668 |
| 44 | negative T cell selection (GO:0043383) | 3.24544985 |
| 45 | ATP synthesis coupled proton transport (GO:0015986) | 3.22549822 |
| 46 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.22549822 |
| 47 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.21076564 |
| 48 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.21076564 |
| 49 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.20635462 |
| 50 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.16109937 |
| 51 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.15986021 |
| 52 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.14882831 |
| 53 | chaperone-mediated protein transport (GO:0072321) | 3.14753865 |
| 54 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.11673028 |
| 55 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.09126424 |
| 56 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.07864026 |
| 57 | cytolysis (GO:0019835) | 3.06963201 |
| 58 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.06721842 |
| 59 | pyrimidine nucleoside catabolic process (GO:0046135) | 3.05622445 |
| 60 | eosinophil migration (GO:0072677) | 3.01735209 |
| 61 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.00851565 |
| 62 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.00640133 |
| 63 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.00640133 |
| 64 | positive regulation of DNA recombination (GO:0045911) | 3.00202753 |
| 65 | positive regulation of calcium-mediated signaling (GO:0050850) | 2.99474776 |
| 66 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 2.98942663 |
| 67 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.97790779 |
| 68 | positive regulation of lymphocyte migration (GO:2000403) | 2.94444752 |
| 69 | macrophage chemotaxis (GO:0048246) | 2.93088469 |
| 70 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.92117903 |
| 71 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.89630789 |
| 72 | termination of RNA polymerase III transcription (GO:0006386) | 2.89630789 |
| 73 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.88005330 |
| 74 | positive regulation of isotype switching (GO:0045830) | 2.86052217 |
| 75 | response to interleukin-15 (GO:0070672) | 2.85203991 |
| 76 | positive regulation of tolerance induction (GO:0002645) | 2.84421885 |
| 77 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.83337040 |
| 78 | maturation of SSU-rRNA (GO:0030490) | 2.81294167 |
| 79 | positive regulation of cell cycle arrest (GO:0071158) | 2.79065160 |
| 80 | respiratory electron transport chain (GO:0022904) | 2.79028970 |
| 81 | regulation of interleukin-8 secretion (GO:2000482) | 2.78657741 |
| 82 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.78041669 |
| 83 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.77672513 |
| 84 | regulation of lymphocyte chemotaxis (GO:1901623) | 2.77584574 |
| 85 | electron transport chain (GO:0022900) | 2.77003495 |
| 86 | positive regulation of cell killing (GO:0031343) | 2.74324301 |
| 87 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2.72891434 |
| 88 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 2.71719251 |
| 89 | positive regulation of T cell chemotaxis (GO:0010820) | 2.71635675 |
| 90 | regulation of T cell chemotaxis (GO:0010819) | 2.71635675 |
| 91 | actin nucleation (GO:0045010) | 2.70571735 |
| 92 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.69131560 |
| 93 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.69131560 |
| 94 | natural killer cell activation (GO:0030101) | 2.69128112 |
| 95 | platelet dense granule organization (GO:0060155) | 2.69032806 |
| 96 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.68720999 |
| 97 | protein complex biogenesis (GO:0070271) | 2.65346597 |
| 98 | regulation of B cell differentiation (GO:0045577) | 2.64874264 |
| 99 | positive regulation of gamma-delta T cell activation (GO:0046645) | 2.64493790 |
| 100 | signal peptide processing (GO:0006465) | 2.64326867 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.60066076 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.06078556 |
| 3 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.03981919 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.83651749 |
| 5 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.66256850 |
| 6 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.45256534 |
| 7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.43226182 |
| 8 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.11630987 |
| 9 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.96839485 |
| 10 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.68742913 |
| 11 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.66016321 |
| 12 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.62540437 |
| 13 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.61430369 |
| 14 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.56944228 |
| 15 | VDR_22108803_ChIP-Seq_LS180_Human | 2.53798677 |
| 16 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.44797074 |
| 17 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.41541967 |
| 18 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.28421631 |
| 19 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.15694714 |
| 20 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.14748641 |
| 21 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.14624508 |
| 22 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.10758830 |
| 23 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.05677440 |
| 24 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.93305651 |
| 25 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.89125126 |
| 26 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.87777231 |
| 27 | MYB_26560356_Chip-Seq_TH2_Human | 1.85739792 |
| 28 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.85323974 |
| 29 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.82009158 |
| 30 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.80501006 |
| 31 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.61629533 |
| 32 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.60799605 |
| 33 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.59553387 |
| 34 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.58509824 |
| 35 | EWS_26573619_Chip-Seq_HEK293_Human | 1.52625489 |
| 36 | GATA3_26560356_Chip-Seq_TH2_Human | 1.51333242 |
| 37 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.50867380 |
| 38 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.48457426 |
| 39 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.46916472 |
| 40 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.37895057 |
| 41 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.37777235 |
| 42 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.36311061 |
| 43 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.36302392 |
| 44 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.34470970 |
| 45 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.33482710 |
| 46 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.32759725 |
| 47 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.32105902 |
| 48 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.30030531 |
| 49 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.26811403 |
| 50 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.26811403 |
| 51 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.26414868 |
| 52 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.25721613 |
| 53 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.25647360 |
| 54 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.24172574 |
| 55 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.20954797 |
| 56 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.19881460 |
| 57 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.19269645 |
| 58 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.18164449 |
| 59 | FUS_26573619_Chip-Seq_HEK293_Human | 1.17203390 |
| 60 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.17123840 |
| 61 | AR_20517297_ChIP-Seq_VCAP_Human | 1.14726337 |
| 62 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.12734975 |
| 63 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.12721204 |
| 64 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.12029579 |
| 65 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.10468456 |
| 66 | NCOR_22424771_ChIP-Seq_293T_Human | 1.09843560 |
| 67 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.08731908 |
| 68 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.08630068 |
| 69 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.08309558 |
| 70 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.07180968 |
| 71 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.07180968 |
| 72 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.06582906 |
| 73 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.05143075 |
| 74 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.04541207 |
| 75 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.04409219 |
| 76 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.02890929 |
| 77 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.01813325 |
| 78 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.00510439 |
| 79 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.97410833 |
| 80 | MYB_26560356_Chip-Seq_TH1_Human | 0.96160205 |
| 81 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.96132830 |
| 82 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.96005653 |
| 83 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.95081698 |
| 84 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.95077691 |
| 85 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.94484594 |
| 86 | P300_19829295_ChIP-Seq_ESCs_Human | 0.94045935 |
| 87 | GATA3_26560356_Chip-Seq_TH1_Human | 0.93541208 |
| 88 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.93210717 |
| 89 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.93183193 |
| 90 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.92240959 |
| 91 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.92240959 |
| 92 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.91753620 |
| 93 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.91154207 |
| 94 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.90455762 |
| 95 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.90455304 |
| 96 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.90160687 |
| 97 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.88989376 |
| 98 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.88816909 |
| 99 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.88600192 |
| 100 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.88209314 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 5.62889651 |
| 2 | MP0001835_abnormal_antigen_presentation | 3.95321843 |
| 3 | MP0003763_abnormal_thymus_physiology | 2.92997336 |
| 4 | MP0009785_altered_susceptibility_to | 2.81566151 |
| 5 | MP0009333_abnormal_splenocyte_physiolog | 2.78166082 |
| 6 | MP0003786_premature_aging | 2.72798388 |
| 7 | MP0001873_stomach_inflammation | 2.61989640 |
| 8 | MP0002148_abnormal_hypersensitivity_rea | 2.29336924 |
| 9 | MP0001790_abnormal_immune_system | 2.11876869 |
| 10 | MP0005387_immune_system_phenotype | 2.11876869 |
| 11 | MP0002138_abnormal_hepatobiliary_system | 2.10903692 |
| 12 | MP0001800_abnormal_humoral_immune | 2.07014482 |
| 13 | MP0005000_abnormal_immune_tolerance | 2.00624224 |
| 14 | MP0001853_heart_inflammation | 1.98554880 |
| 15 | MP0006082_CNS_inflammation | 1.95536415 |
| 16 | MP0002166_altered_tumor_susceptibility | 1.95091182 |
| 17 | MP0009379_abnormal_foot_pigmentation | 1.91011147 |
| 18 | MP0003806_abnormal_nucleotide_metabolis | 1.90500689 |
| 19 | MP0002006_tumorigenesis | 1.85706604 |
| 20 | MP0000685_abnormal_immune_system | 1.82426801 |
| 21 | MP0004145_abnormal_muscle_electrophysio | 1.78037884 |
| 22 | MP0002102_abnormal_ear_morphology | 1.76864302 |
| 23 | MP0002420_abnormal_adaptive_immunity | 1.76172661 |
| 24 | MP0002723_abnormal_immune_serum | 1.74647543 |
| 25 | MP0003195_calcinosis | 1.74139492 |
| 26 | MP0004147_increased_porphyrin_level | 1.73737482 |
| 27 | MP0001819_abnormal_immune_cell | 1.70867202 |
| 28 | MP0005025_abnormal_response_to | 1.67369422 |
| 29 | MP0003866_abnormal_defecation | 1.66873078 |
| 30 | MP0002405_respiratory_system_inflammati | 1.58716854 |
| 31 | MP0001188_hyperpigmentation | 1.55358772 |
| 32 | MP0005084_abnormal_gallbladder_morpholo | 1.54252942 |
| 33 | MP0008058_abnormal_DNA_repair | 1.53926631 |
| 34 | MP0008877_abnormal_DNA_methylation | 1.52478801 |
| 35 | MP0006072_abnormal_retinal_apoptosis | 1.50660417 |
| 36 | MP0002398_abnormal_bone_marrow | 1.46855696 |
| 37 | MP0008995_early_reproductive_senescence | 1.46130871 |
| 38 | MP0002452_abnormal_antigen_presenting | 1.42154450 |
| 39 | MP0002277_abnormal_respiratory_mucosa | 1.42053966 |
| 40 | MP0008875_abnormal_xenobiotic_pharmacok | 1.40111470 |
| 41 | MP0000716_abnormal_immune_system | 1.38203781 |
| 42 | MP0000703_abnormal_thymus_morphology | 1.35349029 |
| 43 | MP0008872_abnormal_physiological_respon | 1.33698426 |
| 44 | MP0010155_abnormal_intestine_physiology | 1.29876451 |
| 45 | MP0000689_abnormal_spleen_morphology | 1.29657447 |
| 46 | MP0005075_abnormal_melanosome_morpholog | 1.28287061 |
| 47 | MP0000372_irregular_coat_pigmentation | 1.27709599 |
| 48 | MP0001661_extended_life_span | 1.27535297 |
| 49 | MP0000465_gastrointestinal_hemorrhage | 1.27001644 |
| 50 | MP0002234_abnormal_pharynx_morphology | 1.26039518 |
| 51 | MP0002722_abnormal_immune_system | 1.25910957 |
| 52 | MP0003045_fibrosis | 1.19072466 |
| 53 | MP0005389_reproductive_system_phenotype | 1.18709056 |
| 54 | MP0003448_altered_tumor_morphology | 1.17444415 |
| 55 | MP0001845_abnormal_inflammatory_respons | 1.13680880 |
| 56 | MP0004957_abnormal_blastocyst_morpholog | 1.12938326 |
| 57 | MP0003878_abnormal_ear_physiology | 1.12834962 |
| 58 | MP0005377_hearing/vestibular/ear_phenot | 1.12834962 |
| 59 | MP0009697_abnormal_copulation | 1.12279789 |
| 60 | MP0002429_abnormal_blood_cell | 1.12267142 |
| 61 | MP0002876_abnormal_thyroid_physiology | 1.11393137 |
| 62 | MP0001919_abnormal_reproductive_system | 1.11250880 |
| 63 | MP0005360_urolithiasis | 1.10867021 |
| 64 | MP0003646_muscle_fatigue | 1.06155054 |
| 65 | MP0002693_abnormal_pancreas_physiology | 1.05595309 |
| 66 | MP0003880_abnormal_central_pattern | 1.03258493 |
| 67 | MP0003567_abnormal_fetal_cardiomyocyte | 1.02741715 |
| 68 | MP0003011_delayed_dark_adaptation | 1.01353523 |
| 69 | MP0006292_abnormal_olfactory_placode | 1.00851704 |
| 70 | MP0002163_abnormal_gland_morphology | 1.00688927 |
| 71 | MP0010094_abnormal_chromosome_stability | 1.00681037 |
| 72 | MP0003693_abnormal_embryo_hatching | 0.99138122 |
| 73 | MP0002933_joint_inflammation | 0.98629602 |
| 74 | MP0005551_abnormal_eye_electrophysiolog | 0.98306886 |
| 75 | MP0002160_abnormal_reproductive_system | 0.98082817 |
| 76 | MP0001501_abnormal_sleep_pattern | 0.97597930 |
| 77 | MP0005253_abnormal_eye_physiology | 0.96888644 |
| 78 | MP0005645_abnormal_hypothalamus_physiol | 0.96232705 |
| 79 | MP0001905_abnormal_dopamine_level | 0.94637943 |
| 80 | MP0006036_abnormal_mitochondrial_physio | 0.94228625 |
| 81 | MP0001968_abnormal_touch/_nociception | 0.92342257 |
| 82 | MP0002837_dystrophic_cardiac_calcinosis | 0.92117836 |
| 83 | MP0002736_abnormal_nociception_after | 0.91407008 |
| 84 | MP0001984_abnormal_olfaction | 0.90889167 |
| 85 | MP0005379_endocrine/exocrine_gland_phen | 0.88750331 |
| 86 | MP0001119_abnormal_female_reproductive | 0.87198631 |
| 87 | MP0003718_maternal_effect | 0.86972544 |
| 88 | MP0008469_abnormal_protein_level | 0.84776097 |
| 89 | MP0002095_abnormal_skin_pigmentation | 0.83485053 |
| 90 | MP0002019_abnormal_tumor_incidence | 0.78758129 |
| 91 | MP0002210_abnormal_sex_determination | 0.77562572 |
| 92 | MP0005410_abnormal_fertilization | 0.72501470 |
| 93 | MP0005083_abnormal_biliary_tract | 0.71698293 |
| 94 | MP0005310_abnormal_salivary_gland | 0.71537158 |
| 95 | MP0004043_abnormal_pH_regulation | 0.69902491 |
| 96 | MP0004381_abnormal_hair_follicle | 0.69244255 |
| 97 | MP0003724_increased_susceptibility_to | 0.67425309 |
| 98 | MP0002419_abnormal_innate_immunity | 0.66928490 |
| 99 | MP0001929_abnormal_gametogenesis | 0.66741812 |
| 100 | MP0009763_increased_sensitivity_to | 0.65404106 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | T lymphocytopenia (HP:0005403) | 4.82941203 |
| 2 | Aplastic anemia (HP:0001915) | 4.64719091 |
| 3 | Abnormality of T cell number (HP:0011839) | 4.62344586 |
| 4 | IgG deficiency (HP:0004315) | 4.40368256 |
| 5 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.36713599 |
| 6 | Severe combined immunodeficiency (HP:0004430) | 3.92125608 |
| 7 | 3-Methylglutaconic aciduria (HP:0003535) | 3.88210871 |
| 8 | Stomatitis (HP:0010280) | 3.78559451 |
| 9 | Hypoproteinemia (HP:0003075) | 3.74641713 |
| 10 | Mitochondrial inheritance (HP:0001427) | 3.64376621 |
| 11 | Congenital, generalized hypertrichosis (HP:0004540) | 3.58948900 |
| 12 | Acute necrotizing encephalopathy (HP:0006965) | 3.42633371 |
| 13 | Increased hepatocellular lipid droplets (HP:0006565) | 3.41955061 |
| 14 | Abnormality of T cells (HP:0002843) | 3.38998663 |
| 15 | Increased CSF lactate (HP:0002490) | 3.38868652 |
| 16 | Thyroiditis (HP:0100646) | 3.15299467 |
| 17 | Lipid accumulation in hepatocytes (HP:0006561) | 3.09939246 |
| 18 | Hepatocellular necrosis (HP:0001404) | 3.06798499 |
| 19 | Increased IgM level (HP:0003496) | 3.05905217 |
| 20 | Combined immunodeficiency (HP:0005387) | 3.05077835 |
| 21 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.98508591 |
| 22 | Increased intramyocellular lipid droplets (HP:0012240) | 2.94671587 |
| 23 | Hepatic necrosis (HP:0002605) | 2.91260302 |
| 24 | Renal Fanconi syndrome (HP:0001994) | 2.89671257 |
| 25 | Congenital stationary night blindness (HP:0007642) | 2.82790017 |
| 26 | Autoimmune hemolytic anemia (HP:0001890) | 2.81851803 |
| 27 | Pancreatic cysts (HP:0001737) | 2.81544034 |
| 28 | Acute encephalopathy (HP:0006846) | 2.80286195 |
| 29 | Progressive macrocephaly (HP:0004481) | 2.80274046 |
| 30 | Abnormality of eosinophils (HP:0001879) | 2.79770317 |
| 31 | Abnormality of the prostate (HP:0008775) | 2.70826102 |
| 32 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.67021260 |
| 33 | Increased serum lactate (HP:0002151) | 2.57280523 |
| 34 | Methylmalonic acidemia (HP:0002912) | 2.53652440 |
| 35 | Generalized aminoaciduria (HP:0002909) | 2.53252447 |
| 36 | Abnormality of midbrain morphology (HP:0002418) | 2.49356865 |
| 37 | Molar tooth sign on MRI (HP:0002419) | 2.49356865 |
| 38 | Abolished electroretinogram (ERG) (HP:0000550) | 2.43091336 |
| 39 | Hypoalbuminemia (HP:0003073) | 2.41848471 |
| 40 | Abnormal albumin level (HP:0012116) | 2.41848471 |
| 41 | Renal cortical cysts (HP:0000803) | 2.40514278 |
| 42 | Increased muscle lipid content (HP:0009058) | 2.38628229 |
| 43 | Cerebral edema (HP:0002181) | 2.38509960 |
| 44 | Exertional dyspnea (HP:0002875) | 2.37251862 |
| 45 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.34970250 |
| 46 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.34970250 |
| 47 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.34890402 |
| 48 | Abnormality of B cell number (HP:0010975) | 2.29671338 |
| 49 | Pancytopenia (HP:0001876) | 2.28349434 |
| 50 | Recurrent bronchitis (HP:0002837) | 2.28091844 |
| 51 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.27463612 |
| 52 | Abnormality of alanine metabolism (HP:0010916) | 2.26399682 |
| 53 | Hyperalaninemia (HP:0003348) | 2.26399682 |
| 54 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.26399682 |
| 55 | Eosinophilia (HP:0001880) | 2.24837727 |
| 56 | Methylmalonic aciduria (HP:0012120) | 2.24613748 |
| 57 | Type II lissencephaly (HP:0007260) | 2.24153935 |
| 58 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.23952796 |
| 59 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.23398673 |
| 60 | B lymphocytopenia (HP:0010976) | 2.20639695 |
| 61 | Optic disc pallor (HP:0000543) | 2.19659561 |
| 62 | True hermaphroditism (HP:0010459) | 2.19015668 |
| 63 | Encephalitis (HP:0002383) | 2.17259207 |
| 64 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.16222847 |
| 65 | Panhypogammaglobulinemia (HP:0003139) | 2.15056721 |
| 66 | Lactic acidosis (HP:0003128) | 2.13299613 |
| 67 | Constricted visual fields (HP:0001133) | 2.12833323 |
| 68 | Abnormality of T cell physiology (HP:0011840) | 2.10170712 |
| 69 | IgM deficiency (HP:0002850) | 2.10140483 |
| 70 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.09191135 |
| 71 | Recurrent cutaneous fungal infections (HP:0011370) | 2.09191135 |
| 72 | Abnormality of urine glucose concentration (HP:0011016) | 2.07649197 |
| 73 | Glycosuria (HP:0003076) | 2.07649197 |
| 74 | Colon cancer (HP:0003003) | 2.07473452 |
| 75 | Chronic diarrhea (HP:0002028) | 2.06935006 |
| 76 | Abnormality of the pons (HP:0007361) | 2.06917338 |
| 77 | Lethargy (HP:0001254) | 1.94903433 |
| 78 | Lymphopenia (HP:0001888) | 1.94844538 |
| 79 | Type I transferrin isoform profile (HP:0003642) | 1.93697086 |
| 80 | Cerebellar dysplasia (HP:0007033) | 1.88648846 |
| 81 | Hypoplasia of the pons (HP:0012110) | 1.85529666 |
| 82 | Lymphoma (HP:0002665) | 1.84821554 |
| 83 | Abnormality of the renal cortex (HP:0011035) | 1.82776042 |
| 84 | Pancreatic fibrosis (HP:0100732) | 1.82401193 |
| 85 | Agammaglobulinemia (HP:0004432) | 1.82238342 |
| 86 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.82206624 |
| 87 | Respiratory failure (HP:0002878) | 1.80822532 |
| 88 | Nephronophthisis (HP:0000090) | 1.80148367 |
| 89 | Hypoplasia of the thymus (HP:0000778) | 1.78740585 |
| 90 | Dicarboxylic aciduria (HP:0003215) | 1.78553619 |
| 91 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.78553619 |
| 92 | Leukocytosis (HP:0001974) | 1.77666211 |
| 93 | Autoimmune thrombocytopenia (HP:0001973) | 1.77538904 |
| 94 | Attenuation of retinal blood vessels (HP:0007843) | 1.74572367 |
| 95 | Decreased central vision (HP:0007663) | 1.74132346 |
| 96 | Recurrent viral infections (HP:0004429) | 1.71288705 |
| 97 | Palpitations (HP:0001962) | 1.70604983 |
| 98 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.69565020 |
| 99 | Exercise intolerance (HP:0003546) | 1.68997180 |
| 100 | Absent thumb (HP:0009777) | 1.68961106 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 6.38002190 |
| 2 | KDR | 3.54432983 |
| 3 | VRK2 | 3.30776956 |
| 4 | ZAK | 2.80424220 |
| 5 | TESK2 | 2.70725674 |
| 6 | EIF2AK3 | 2.68707080 |
| 7 | TAOK3 | 2.60991137 |
| 8 | BUB1 | 2.59582006 |
| 9 | NUAK1 | 2.29196901 |
| 10 | ADRBK2 | 2.29189288 |
| 11 | ITK | 2.25112324 |
| 12 | BCKDK | 2.10465551 |
| 13 | MST4 | 2.03908357 |
| 14 | MAP4K1 | 1.96996678 |
| 15 | TLK1 | 1.91112957 |
| 16 | VRK1 | 1.90543941 |
| 17 | BMPR1B | 1.88500080 |
| 18 | TEC | 1.82851598 |
| 19 | GRK1 | 1.71497661 |
| 20 | TSSK6 | 1.57077601 |
| 21 | NME1 | 1.53520837 |
| 22 | PASK | 1.53309821 |
| 23 | EIF2AK1 | 1.36243399 |
| 24 | WNK4 | 1.29415284 |
| 25 | FRK | 1.22416214 |
| 26 | NEK1 | 1.18122104 |
| 27 | STK16 | 1.16282126 |
| 28 | MAPKAPK3 | 1.14337988 |
| 29 | MAP4K2 | 1.12526374 |
| 30 | PBK | 1.09419202 |
| 31 | PRKCQ | 1.09016371 |
| 32 | CSK | 1.07772561 |
| 33 | SYK | 1.07631464 |
| 34 | FES | 1.07177961 |
| 35 | TAF1 | 1.05507919 |
| 36 | PLK3 | 1.04896092 |
| 37 | NLK | 1.04833386 |
| 38 | LCK | 1.01851320 |
| 39 | BTK | 0.99036641 |
| 40 | SRPK1 | 0.97584392 |
| 41 | LIMK1 | 0.94627223 |
| 42 | MAP2K6 | 0.93132270 |
| 43 | TGFBR1 | 0.89539055 |
| 44 | WNK3 | 0.87851967 |
| 45 | IKBKE | 0.87554756 |
| 46 | IKBKB | 0.85271985 |
| 47 | TRIM28 | 0.81942237 |
| 48 | MUSK | 0.81532318 |
| 49 | GRK7 | 0.78010147 |
| 50 | EIF2AK2 | 0.76960221 |
| 51 | INSRR | 0.76195068 |
| 52 | MAPKAPK5 | 0.69042382 |
| 53 | PLK4 | 0.67334975 |
| 54 | TIE1 | 0.65197051 |
| 55 | TNK2 | 0.62311024 |
| 56 | CDK19 | 0.62310804 |
| 57 | TESK1 | 0.61559529 |
| 58 | MKNK1 | 0.61100395 |
| 59 | KIT | 0.61029743 |
| 60 | SCYL2 | 0.59448801 |
| 61 | DAPK1 | 0.59093174 |
| 62 | RPS6KA5 | 0.58215470 |
| 63 | LYN | 0.57575248 |
| 64 | CDC7 | 0.56843835 |
| 65 | CDK8 | 0.55551522 |
| 66 | OXSR1 | 0.54616562 |
| 67 | ZAP70 | 0.53808453 |
| 68 | WEE1 | 0.52712917 |
| 69 | ATR | 0.50553684 |
| 70 | STK39 | 0.50050034 |
| 71 | MYLK | 0.49575759 |
| 72 | PLK2 | 0.48300440 |
| 73 | CAMKK2 | 0.46729917 |
| 74 | PIK3CA | 0.46214936 |
| 75 | MAP3K12 | 0.45010550 |
| 76 | ADRBK1 | 0.43916377 |
| 77 | JAK3 | 0.42863049 |
| 78 | PINK1 | 0.42814228 |
| 79 | IGF1R | 0.42793084 |
| 80 | RPS6KA4 | 0.41659092 |
| 81 | PIK3CG | 0.40086904 |
| 82 | CSNK2A1 | 0.39046946 |
| 83 | CSNK1G1 | 0.38721520 |
| 84 | GRK6 | 0.38434517 |
| 85 | OBSCN | 0.38261020 |
| 86 | PLK1 | 0.37408679 |
| 87 | CSNK2A2 | 0.36024625 |
| 88 | PHKG2 | 0.34320276 |
| 89 | PHKG1 | 0.34320276 |
| 90 | FGFR1 | 0.34042337 |
| 91 | CDK3 | 0.33687844 |
| 92 | ALK | 0.33515427 |
| 93 | PDK2 | 0.32593092 |
| 94 | PRKCA | 0.32381700 |
| 95 | AURKB | 0.30895845 |
| 96 | BCR | 0.30416004 |
| 97 | PIM1 | 0.29333861 |
| 98 | CSF1R | 0.28000100 |
| 99 | AURKA | 0.27713026 |
| 100 | DAPK2 | 0.26901999 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.94592881 |
| 2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.42885118 |
| 3 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.04451199 |
| 4 | Allograft rejection_Homo sapiens_hsa05330 | 2.95217507 |
| 5 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.86612098 |
| 6 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.74802766 |
| 7 | Protein export_Homo sapiens_hsa03060 | 2.71333558 |
| 8 | Ribosome_Homo sapiens_hsa03010 | 2.69128534 |
| 9 | RNA polymerase_Homo sapiens_hsa03020 | 2.48198146 |
| 10 | Parkinsons disease_Homo sapiens_hsa05012 | 2.41478517 |
| 11 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.37429774 |
| 12 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.33297139 |
| 13 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.32178705 |
| 14 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.05543005 |
| 15 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.97772223 |
| 16 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.84140874 |
| 17 | Asthma_Homo sapiens_hsa05310 | 1.83855128 |
| 18 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.82917643 |
| 19 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.63139490 |
| 20 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.56953888 |
| 21 | Homologous recombination_Homo sapiens_hsa03440 | 1.52313618 |
| 22 | Huntingtons disease_Homo sapiens_hsa05016 | 1.47967889 |
| 23 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.47656646 |
| 24 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.44875329 |
| 25 | Alzheimers disease_Homo sapiens_hsa05010 | 1.44110653 |
| 26 | DNA replication_Homo sapiens_hsa03030 | 1.43668475 |
| 27 | RNA degradation_Homo sapiens_hsa03018 | 1.39249062 |
| 28 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.37281755 |
| 29 | Mismatch repair_Homo sapiens_hsa03430 | 1.32384497 |
| 30 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.31990550 |
| 31 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.29108096 |
| 32 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.20612049 |
| 33 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.19582728 |
| 34 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.16057399 |
| 35 | Basal transcription factors_Homo sapiens_hsa03022 | 1.11960702 |
| 36 | Phototransduction_Homo sapiens_hsa04744 | 1.09714997 |
| 37 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.08453727 |
| 38 | RNA transport_Homo sapiens_hsa03013 | 1.06975424 |
| 39 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.06606325 |
| 40 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.05456696 |
| 41 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.04674306 |
| 42 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.02083761 |
| 43 | Measles_Homo sapiens_hsa05162 | 1.01471639 |
| 44 | Spliceosome_Homo sapiens_hsa03040 | 0.99985520 |
| 45 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.96656157 |
| 46 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.93183100 |
| 47 | Purine metabolism_Homo sapiens_hsa00230 | 0.92319180 |
| 48 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.88858386 |
| 49 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.88767469 |
| 50 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.85278993 |
| 51 | Peroxisome_Homo sapiens_hsa04146 | 0.82430757 |
| 52 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.81272724 |
| 53 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.79638440 |
| 54 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.76112412 |
| 55 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.74318997 |
| 56 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.73214361 |
| 57 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.70665671 |
| 58 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.64037648 |
| 59 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.60518310 |
| 60 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.59437600 |
| 61 | Viral myocarditis_Homo sapiens_hsa05416 | 0.58093251 |
| 62 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.55384335 |
| 63 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.52912673 |
| 64 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.52387957 |
| 65 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.51347442 |
| 66 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.50250522 |
| 67 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.49024702 |
| 68 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.46968238 |
| 69 | Base excision repair_Homo sapiens_hsa03410 | 0.45697840 |
| 70 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.45034878 |
| 71 | Retinol metabolism_Homo sapiens_hsa00830 | 0.43949474 |
| 72 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.42140907 |
| 73 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.41369498 |
| 74 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.41036325 |
| 75 | Salmonella infection_Homo sapiens_hsa05132 | 0.40760484 |
| 76 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.39130921 |
| 77 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.38466257 |
| 78 | Metabolic pathways_Homo sapiens_hsa01100 | 0.38156557 |
| 79 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.38087454 |
| 80 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.37343812 |
| 81 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.37113989 |
| 82 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.36638421 |
| 83 | Olfactory transduction_Homo sapiens_hsa04740 | 0.36009401 |
| 84 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.35382240 |
| 85 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.33800690 |
| 86 | Malaria_Homo sapiens_hsa05144 | 0.32846113 |
| 87 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.32092866 |
| 88 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.30384162 |
| 89 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.29344011 |
| 90 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.25634881 |
| 91 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.25437779 |
| 92 | HTLV-I infection_Homo sapiens_hsa05166 | 0.25309879 |
| 93 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.24792899 |
| 94 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.24276816 |
| 95 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.22829967 |
| 96 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.22700626 |
| 97 | Shigellosis_Homo sapiens_hsa05131 | 0.22378021 |
| 98 | Mineral absorption_Homo sapiens_hsa04978 | 0.20545224 |
| 99 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.19608556 |
| 100 | Taste transduction_Homo sapiens_hsa04742 | 0.19255437 |

