

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 5.54384428 |
| 2 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 5.21598528 |
| 3 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.83515913 |
| 4 | proteasome assembly (GO:0043248) | 4.80572619 |
| 5 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 4.68298515 |
| 6 | maturation of 5.8S rRNA (GO:0000460) | 4.65493997 |
| 7 | ribosome assembly (GO:0042255) | 4.16682140 |
| 8 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.13221386 |
| 9 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.00078663 |
| 10 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.99673898 |
| 11 | rRNA modification (GO:0000154) | 3.88633523 |
| 12 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.83883861 |
| 13 | chaperone-mediated protein transport (GO:0072321) | 3.83147362 |
| 14 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.79199614 |
| 15 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.79199614 |
| 16 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.79199614 |
| 17 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.78352610 |
| 18 | respiratory chain complex IV assembly (GO:0008535) | 3.78058931 |
| 19 | pseudouridine synthesis (GO:0001522) | 3.77039304 |
| 20 | negative regulation of ligase activity (GO:0051352) | 3.74663502 |
| 21 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.74663502 |
| 22 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.74371300 |
| 23 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.74371300 |
| 24 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.73980826 |
| 25 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.68562228 |
| 26 | DNA double-strand break processing (GO:0000729) | 3.68111009 |
| 27 | regulation of immunoglobulin secretion (GO:0051023) | 3.67509889 |
| 28 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.66871376 |
| 29 | chromatin remodeling at centromere (GO:0031055) | 3.63866602 |
| 30 | CENP-A containing nucleosome assembly (GO:0034080) | 3.62198398 |
| 31 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.60865665 |
| 32 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.60865665 |
| 33 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.60302631 |
| 34 | positive regulation of isotype switching (GO:0045830) | 3.58863422 |
| 35 | positive regulation of DNA recombination (GO:0045911) | 3.57698377 |
| 36 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.55759652 |
| 37 | isotype switching (GO:0045190) | 3.55759652 |
| 38 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.55759652 |
| 39 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.54787539 |
| 40 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.54470263 |
| 41 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.54409031 |
| 42 | cullin deneddylation (GO:0010388) | 3.52634766 |
| 43 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.48606898 |
| 44 | ATP synthesis coupled proton transport (GO:0015986) | 3.48606898 |
| 45 | rRNA methylation (GO:0031167) | 3.47949944 |
| 46 | protein deneddylation (GO:0000338) | 3.45430728 |
| 47 | regulation of podosome assembly (GO:0071801) | 3.44343667 |
| 48 | protein K6-linked ubiquitination (GO:0085020) | 3.41355994 |
| 49 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.37991494 |
| 50 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.37601317 |
| 51 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.35199907 |
| 52 | protein neddylation (GO:0045116) | 3.32830378 |
| 53 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.27829788 |
| 54 | termination of RNA polymerase III transcription (GO:0006386) | 3.26350342 |
| 55 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.26350342 |
| 56 | positive regulation of interleukin-17 production (GO:0032740) | 3.25899652 |
| 57 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.25306158 |
| 58 | cytochrome complex assembly (GO:0017004) | 3.15378467 |
| 59 | positive regulation of ligase activity (GO:0051351) | 3.10706216 |
| 60 | cytidine deamination (GO:0009972) | 3.07276723 |
| 61 | cytidine metabolic process (GO:0046087) | 3.07276723 |
| 62 | cytidine catabolic process (GO:0006216) | 3.07276723 |
| 63 | histone exchange (GO:0043486) | 3.06672194 |
| 64 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.04349042 |
| 65 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.00600050 |
| 66 | protein complex biogenesis (GO:0070271) | 3.00569709 |
| 67 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.96597258 |
| 68 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.96597258 |
| 69 | regulation of cellular amine metabolic process (GO:0033238) | 2.95564525 |
| 70 | platelet dense granule organization (GO:0060155) | 2.93762758 |
| 71 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.89939605 |
| 72 | protein targeting to mitochondrion (GO:0006626) | 2.87085335 |
| 73 | amino acid salvage (GO:0043102) | 2.86851484 |
| 74 | L-methionine salvage (GO:0071267) | 2.86851484 |
| 75 | L-methionine biosynthetic process (GO:0071265) | 2.86851484 |
| 76 | nucleobase biosynthetic process (GO:0046112) | 2.84771986 |
| 77 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.83214828 |
| 78 | rRNA processing (GO:0006364) | 2.81537855 |
| 79 | positive regulation of cell cycle arrest (GO:0071158) | 2.81015571 |
| 80 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.80893394 |
| 81 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.79751826 |
| 82 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.79751826 |
| 83 | NADH dehydrogenase complex assembly (GO:0010257) | 2.79751826 |
| 84 | purine nucleobase biosynthetic process (GO:0009113) | 2.78330355 |
| 85 | GTP biosynthetic process (GO:0006183) | 2.78193587 |
| 86 | termination of RNA polymerase I transcription (GO:0006363) | 2.77766760 |
| 87 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.77636889 |
| 88 | ribosomal large subunit biogenesis (GO:0042273) | 2.76581011 |
| 89 | response to pheromone (GO:0019236) | 2.76348320 |
| 90 | DNA damage response, detection of DNA damage (GO:0042769) | 2.75307410 |
| 91 | IMP biosynthetic process (GO:0006188) | 2.74736457 |
| 92 | rRNA metabolic process (GO:0016072) | 2.73685525 |
| 93 | ribosome biogenesis (GO:0042254) | 2.71505438 |
| 94 | branched-chain amino acid catabolic process (GO:0009083) | 2.71251936 |
| 95 | regulation of ligase activity (GO:0051340) | 2.70736601 |
| 96 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.70693877 |
| 97 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.68593233 |
| 98 | spliceosomal snRNP assembly (GO:0000387) | 2.66191590 |
| 99 | tRNA processing (GO:0008033) | 2.65550436 |
| 100 | establishment of protein localization to mitochondrion (GO:0072655) | 2.65463031 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.07946523 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.37613400 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.73118887 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.66046650 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.99002114 |
| 6 | VDR_22108803_ChIP-Seq_LS180_Human | 2.92167800 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.85149177 |
| 8 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.78813917 |
| 9 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.74197381 |
| 10 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.71703290 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.70040898 |
| 12 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.68835192 |
| 13 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.65985369 |
| 14 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.65942700 |
| 15 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.56478285 |
| 16 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.50223356 |
| 17 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.47410945 |
| 18 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.37225369 |
| 19 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.37061691 |
| 20 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.30992846 |
| 21 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.23704442 |
| 22 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.18710483 |
| 23 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.14612799 |
| 24 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.14192501 |
| 25 | EWS_26573619_Chip-Seq_HEK293_Human | 2.03468489 |
| 26 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.94096983 |
| 27 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.83984927 |
| 28 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.79375609 |
| 29 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.71772281 |
| 30 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.69403072 |
| 31 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.65811256 |
| 32 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.65193585 |
| 33 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.64327987 |
| 34 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.56173963 |
| 35 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.52532383 |
| 36 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.49892320 |
| 37 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.49459592 |
| 38 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.48346818 |
| 39 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.44724761 |
| 40 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.40400596 |
| 41 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.39923981 |
| 42 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.38742789 |
| 43 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.36400861 |
| 44 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.33881612 |
| 45 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.31549774 |
| 46 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.31399166 |
| 47 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.30810453 |
| 48 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.29798186 |
| 49 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.25896989 |
| 50 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.24437528 |
| 51 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.23980150 |
| 52 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.23925819 |
| 53 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.23657622 |
| 54 | FUS_26573619_Chip-Seq_HEK293_Human | 1.23413419 |
| 55 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.23269734 |
| 56 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.22318766 |
| 57 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.21656659 |
| 58 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.21656659 |
| 59 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.20012706 |
| 60 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.18630360 |
| 61 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.18630360 |
| 62 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.18075723 |
| 63 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.16696835 |
| 64 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.16270287 |
| 65 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.16006705 |
| 66 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.14730506 |
| 67 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.13563087 |
| 68 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.13456651 |
| 69 | P300_19829295_ChIP-Seq_ESCs_Human | 1.13311398 |
| 70 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.10668229 |
| 71 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.06846232 |
| 72 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.06573930 |
| 73 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.06517696 |
| 74 | AR_20517297_ChIP-Seq_VCAP_Human | 1.04765218 |
| 75 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.02693732 |
| 76 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.01921537 |
| 77 | GATA3_26560356_Chip-Seq_TH2_Human | 1.01000382 |
| 78 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.00907697 |
| 79 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.99403875 |
| 80 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.98174964 |
| 81 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 0.97367518 |
| 82 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.97256406 |
| 83 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.97076658 |
| 84 | NCOR_22424771_ChIP-Seq_293T_Human | 0.96187392 |
| 85 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.94894390 |
| 86 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.94202866 |
| 87 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 0.94173744 |
| 88 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.93287970 |
| 89 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.92904045 |
| 90 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.92777650 |
| 91 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.91249465 |
| 92 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.91141609 |
| 93 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.90934905 |
| 94 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.90371159 |
| 95 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.87426063 |
| 96 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.85313160 |
| 97 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.83648341 |
| 98 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.83408319 |
| 99 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.82523709 |
| 100 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.82523709 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001835_abnormal_antigen_presentation | 4.15180045 |
| 2 | MP0008877_abnormal_DNA_methylation | 3.23287840 |
| 3 | MP0005084_abnormal_gallbladder_morpholo | 3.13642657 |
| 4 | MP0001873_stomach_inflammation | 3.11609703 |
| 5 | MP0002102_abnormal_ear_morphology | 2.87661245 |
| 6 | MP0008058_abnormal_DNA_repair | 2.72980252 |
| 7 | MP0008872_abnormal_physiological_respon | 2.60613050 |
| 8 | MP0006292_abnormal_olfactory_placode | 2.57027616 |
| 9 | MP0005671_abnormal_response_to | 2.47458605 |
| 10 | MP0004147_increased_porphyrin_level | 2.44915638 |
| 11 | MP0003195_calcinosis | 2.39097403 |
| 12 | MP0003718_maternal_effect | 2.30232425 |
| 13 | MP0010094_abnormal_chromosome_stability | 2.20048746 |
| 14 | MP0003786_premature_aging | 2.19091769 |
| 15 | MP0004782_abnormal_surfactant_physiolog | 2.12422309 |
| 16 | MP0009333_abnormal_splenocyte_physiolog | 2.08668007 |
| 17 | MP0003693_abnormal_embryo_hatching | 2.05339897 |
| 18 | MP0008875_abnormal_xenobiotic_pharmacok | 2.04978552 |
| 19 | MP0006036_abnormal_mitochondrial_physio | 1.97914558 |
| 20 | MP0002138_abnormal_hepatobiliary_system | 1.94944755 |
| 21 | MP0001188_hyperpigmentation | 1.93786097 |
| 22 | MP0004957_abnormal_blastocyst_morpholog | 1.89481683 |
| 23 | MP0009785_altered_susceptibility_to | 1.81463916 |
| 24 | MP0001984_abnormal_olfaction | 1.72875892 |
| 25 | MP0003880_abnormal_central_pattern | 1.69380292 |
| 26 | MP0002148_abnormal_hypersensitivity_rea | 1.62724340 |
| 27 | MP0008007_abnormal_cellular_replicative | 1.62112280 |
| 28 | MP0005645_abnormal_hypothalamus_physiol | 1.58390437 |
| 29 | MP0006035_abnormal_mitochondrial_morpho | 1.57544863 |
| 30 | MP0005646_abnormal_pituitary_gland | 1.56183609 |
| 31 | MP0001800_abnormal_humoral_immune | 1.52920872 |
| 32 | MP0003806_abnormal_nucleotide_metabolis | 1.52459812 |
| 33 | MP0002736_abnormal_nociception_after | 1.49055410 |
| 34 | MP0003186_abnormal_redox_activity | 1.47464140 |
| 35 | MP0005387_immune_system_phenotype | 1.46707602 |
| 36 | MP0001790_abnormal_immune_system | 1.46707602 |
| 37 | MP0003111_abnormal_nucleus_morphology | 1.45189366 |
| 38 | MP0001968_abnormal_touch/_nociception | 1.44249196 |
| 39 | MP0006072_abnormal_retinal_apoptosis | 1.43209644 |
| 40 | MP0002837_dystrophic_cardiac_calcinosis | 1.42073804 |
| 41 | MP0002876_abnormal_thyroid_physiology | 1.40084984 |
| 42 | MP0005551_abnormal_eye_electrophysiolog | 1.39912095 |
| 43 | MP0004145_abnormal_muscle_electrophysio | 1.37468816 |
| 44 | MP0005000_abnormal_immune_tolerance | 1.37037187 |
| 45 | MP0001986_abnormal_taste_sensitivity | 1.32289461 |
| 46 | MP0000372_irregular_coat_pigmentation | 1.26873279 |
| 47 | MP0003077_abnormal_cell_cycle | 1.23986170 |
| 48 | MP0001853_heart_inflammation | 1.20509276 |
| 49 | MP0004215_abnormal_myocardial_fiber | 1.20385662 |
| 50 | MP0003567_abnormal_fetal_cardiomyocyte | 1.20227259 |
| 51 | MP0001764_abnormal_homeostasis | 1.16598323 |
| 52 | MP0002166_altered_tumor_susceptibility | 1.13726095 |
| 53 | MP0002006_tumorigenesis | 1.12263747 |
| 54 | MP0000685_abnormal_immune_system | 1.11714595 |
| 55 | MP0009697_abnormal_copulation | 1.09280184 |
| 56 | MP0005075_abnormal_melanosome_morpholog | 1.08773499 |
| 57 | MP0002405_respiratory_system_inflammati | 1.07019690 |
| 58 | MP0002277_abnormal_respiratory_mucosa | 1.06894062 |
| 59 | MP0005410_abnormal_fertilization | 1.05041832 |
| 60 | MP0001529_abnormal_vocalization | 1.03180335 |
| 61 | MP0003646_muscle_fatigue | 1.01113956 |
| 62 | MP0002723_abnormal_immune_serum | 1.00125444 |
| 63 | MP0001881_abnormal_mammary_gland | 0.99928137 |
| 64 | MP0001293_anophthalmia | 0.99370995 |
| 65 | MP0002160_abnormal_reproductive_system | 0.99284444 |
| 66 | MP0002751_abnormal_autonomic_nervous | 0.96231193 |
| 67 | MP0002420_abnormal_adaptive_immunity | 0.94458095 |
| 68 | MP0000689_abnormal_spleen_morphology | 0.92577108 |
| 69 | MP0003136_yellow_coat_color | 0.91496129 |
| 70 | MP0005253_abnormal_eye_physiology | 0.91381181 |
| 71 | MP0004885_abnormal_endolymph | 0.91107086 |
| 72 | MP0001819_abnormal_immune_cell | 0.89594392 |
| 73 | MP0002210_abnormal_sex_determination | 0.88589721 |
| 74 | MP0002452_abnormal_antigen_presenting | 0.87783122 |
| 75 | MP0010307_abnormal_tumor_latency | 0.87730218 |
| 76 | MP0002282_abnormal_trachea_morphology | 0.87336074 |
| 77 | MP0005389_reproductive_system_phenotype | 0.86807989 |
| 78 | MP0001929_abnormal_gametogenesis | 0.86236101 |
| 79 | MP0005636_abnormal_mineral_homeostasis | 0.85819440 |
| 80 | MP0003011_delayed_dark_adaptation | 0.83081816 |
| 81 | MP0005085_abnormal_gallbladder_physiolo | 0.81728285 |
| 82 | MP0001661_extended_life_span | 0.81506300 |
| 83 | MP0005395_other_phenotype | 0.81129371 |
| 84 | MP0002019_abnormal_tumor_incidence | 0.80118967 |
| 85 | MP0001119_abnormal_female_reproductive | 0.79598018 |
| 86 | MP0003866_abnormal_defecation | 0.77122212 |
| 87 | MP0005332_abnormal_amino_acid | 0.76512966 |
| 88 | MP0010155_abnormal_intestine_physiology | 0.75334150 |
| 89 | MP0003252_abnormal_bile_duct | 0.74045623 |
| 90 | MP0001485_abnormal_pinna_reflex | 0.73923976 |
| 91 | MP0002693_abnormal_pancreas_physiology | 0.73649511 |
| 92 | MP0002398_abnormal_bone_marrow | 0.71773530 |
| 93 | MP0002234_abnormal_pharynx_morphology | 0.71318115 |
| 94 | MP0001845_abnormal_inflammatory_respons | 0.70961472 |
| 95 | MP0003936_abnormal_reproductive_system | 0.70171441 |
| 96 | MP0002396_abnormal_hematopoietic_system | 0.70014635 |
| 97 | MP0000653_abnormal_sex_gland | 0.69647318 |
| 98 | MP0003950_abnormal_plasma_membrane | 0.69159960 |
| 99 | MP0005310_abnormal_salivary_gland | 0.67599365 |
| 100 | MP0002272_abnormal_nervous_system | 0.67340346 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Stomatitis (HP:0010280) | 3.93526916 |
| 2 | 3-Methylglutaconic aciduria (HP:0003535) | 3.81231118 |
| 3 | Increased hepatocellular lipid droplets (HP:0006565) | 3.68972486 |
| 4 | Increased CSF lactate (HP:0002490) | 3.65766233 |
| 5 | Mitochondrial inheritance (HP:0001427) | 3.54956995 |
| 6 | Acute necrotizing encephalopathy (HP:0006965) | 3.51693860 |
| 7 | Lipid accumulation in hepatocytes (HP:0006561) | 3.49720367 |
| 8 | Abnormality of the pons (HP:0007361) | 3.47529502 |
| 9 | Acute encephalopathy (HP:0006846) | 3.25568260 |
| 10 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.05781372 |
| 11 | Increased serum lactate (HP:0002151) | 3.03930742 |
| 12 | Hepatocellular necrosis (HP:0001404) | 2.98787857 |
| 13 | Hypoplasia of the pons (HP:0012110) | 2.96057460 |
| 14 | Progressive macrocephaly (HP:0004481) | 2.95471742 |
| 15 | Congenital stationary night blindness (HP:0007642) | 2.94803850 |
| 16 | Pancreatic cysts (HP:0001737) | 2.90636529 |
| 17 | IgG deficiency (HP:0004315) | 2.88469477 |
| 18 | Exertional dyspnea (HP:0002875) | 2.87874982 |
| 19 | Hepatic necrosis (HP:0002605) | 2.83684924 |
| 20 | Decreased central vision (HP:0007663) | 2.83607312 |
| 21 | Aplastic anemia (HP:0001915) | 2.83410614 |
| 22 | Renal Fanconi syndrome (HP:0001994) | 2.76407098 |
| 23 | Methylmalonic acidemia (HP:0002912) | 2.68203081 |
| 24 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.63217119 |
| 25 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.58109891 |
| 26 | Cerebral edema (HP:0002181) | 2.57567497 |
| 27 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.54196484 |
| 28 | Congenital, generalized hypertrichosis (HP:0004540) | 2.51626388 |
| 29 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.48649844 |
| 30 | Hyperglycinuria (HP:0003108) | 2.46961056 |
| 31 | Lactic acidosis (HP:0003128) | 2.45411453 |
| 32 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.44743764 |
| 33 | Cerebral hypomyelination (HP:0006808) | 2.44503689 |
| 34 | Type II lissencephaly (HP:0007260) | 2.42743332 |
| 35 | Colon cancer (HP:0003003) | 2.41252474 |
| 36 | Increased IgM level (HP:0003496) | 2.40601080 |
| 37 | Increased intramyocellular lipid droplets (HP:0012240) | 2.39638670 |
| 38 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.35800833 |
| 39 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.33112621 |
| 40 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.33112621 |
| 41 | Abolished electroretinogram (ERG) (HP:0000550) | 2.27972711 |
| 42 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.24567571 |
| 43 | Methylmalonic aciduria (HP:0012120) | 2.23178349 |
| 44 | Optic disc pallor (HP:0000543) | 2.23137467 |
| 45 | Pancreatic fibrosis (HP:0100732) | 2.22578014 |
| 46 | Lethargy (HP:0001254) | 2.22280023 |
| 47 | Attenuation of retinal blood vessels (HP:0007843) | 2.20154163 |
| 48 | Large for gestational age (HP:0001520) | 2.18779941 |
| 49 | Increased serum pyruvate (HP:0003542) | 2.18385480 |
| 50 | Abnormality of alanine metabolism (HP:0010916) | 2.16672990 |
| 51 | Hyperalaninemia (HP:0003348) | 2.16672990 |
| 52 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.16672990 |
| 53 | Abnormality of methionine metabolism (HP:0010901) | 2.15852976 |
| 54 | Respiratory difficulties (HP:0002880) | 2.14050492 |
| 55 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.04884858 |
| 56 | Abnormality of glycine metabolism (HP:0010895) | 2.04884858 |
| 57 | Progressive microcephaly (HP:0000253) | 2.04702649 |
| 58 | Severe combined immunodeficiency (HP:0004430) | 2.04509219 |
| 59 | Exercise intolerance (HP:0003546) | 2.02304204 |
| 60 | Respiratory failure (HP:0002878) | 2.01890523 |
| 61 | Increased muscle lipid content (HP:0009058) | 2.01716052 |
| 62 | Abnormality of serum amino acid levels (HP:0003112) | 2.00318828 |
| 63 | True hermaphroditism (HP:0010459) | 1.99830959 |
| 64 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.99436665 |
| 65 | Meckel diverticulum (HP:0002245) | 1.98327833 |
| 66 | Abnormality of the renal cortex (HP:0011035) | 1.96860191 |
| 67 | Fibular aplasia (HP:0002990) | 1.94591909 |
| 68 | Oral leukoplakia (HP:0002745) | 1.93244141 |
| 69 | Pendular nystagmus (HP:0012043) | 1.92894498 |
| 70 | Abnormality of the ileum (HP:0001549) | 1.92644157 |
| 71 | Abnormality of midbrain morphology (HP:0002418) | 1.92588280 |
| 72 | Molar tooth sign on MRI (HP:0002419) | 1.92588280 |
| 73 | Type I transferrin isoform profile (HP:0003642) | 1.91672566 |
| 74 | Chronic sinusitis (HP:0011109) | 1.89188110 |
| 75 | Abnormality of T cell physiology (HP:0011840) | 1.88945799 |
| 76 | Nephronophthisis (HP:0000090) | 1.86334488 |
| 77 | CNS demyelination (HP:0007305) | 1.84934938 |
| 78 | Abnormality of the prostate (HP:0008775) | 1.83579483 |
| 79 | IgA deficiency (HP:0002720) | 1.83506526 |
| 80 | Microvesicular hepatic steatosis (HP:0001414) | 1.83411834 |
| 81 | Adactyly (HP:0009776) | 1.82476834 |
| 82 | Pancytopenia (HP:0001876) | 1.81394008 |
| 83 | Abnormality of T cells (HP:0002843) | 1.80900676 |
| 84 | Duplicated collecting system (HP:0000081) | 1.80509354 |
| 85 | Constricted visual fields (HP:0001133) | 1.78583804 |
| 86 | Abnormality of T cell number (HP:0011839) | 1.77355787 |
| 87 | Duodenal stenosis (HP:0100867) | 1.77165246 |
| 88 | Small intestinal stenosis (HP:0012848) | 1.77165246 |
| 89 | Polydipsia (HP:0001959) | 1.76802603 |
| 90 | Abnormal drinking behavior (HP:0030082) | 1.76802603 |
| 91 | Abnormality of urine glucose concentration (HP:0011016) | 1.75999895 |
| 92 | Glycosuria (HP:0003076) | 1.75999895 |
| 93 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.75792960 |
| 94 | Thyroiditis (HP:0100646) | 1.75585315 |
| 95 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.75218907 |
| 96 | Abnormality of the labia minora (HP:0012880) | 1.74944021 |
| 97 | Abnormal spermatogenesis (HP:0008669) | 1.74561627 |
| 98 | Leukodystrophy (HP:0002415) | 1.74058081 |
| 99 | Abnormality of the renal collecting system (HP:0004742) | 1.72483173 |
| 100 | Hypothermia (HP:0002045) | 1.72390938 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EIF2AK3 | 4.25099525 |
| 2 | MST4 | 3.83193000 |
| 3 | EIF2AK1 | 3.71448316 |
| 4 | TSSK6 | 3.28285866 |
| 5 | VRK2 | 3.07630643 |
| 6 | ZAK | 2.85024686 |
| 7 | NUAK1 | 2.69259616 |
| 8 | BUB1 | 2.64769930 |
| 9 | BMPR1B | 2.59950689 |
| 10 | SRPK1 | 2.43628380 |
| 11 | VRK1 | 2.25590699 |
| 12 | PBK | 2.24309355 |
| 13 | TLK1 | 2.15529382 |
| 14 | TXK | 2.13427132 |
| 15 | PLK3 | 2.11045872 |
| 16 | MKNK2 | 2.10026364 |
| 17 | TNIK | 1.96090529 |
| 18 | STK16 | 1.83279250 |
| 19 | ADRBK2 | 1.77515728 |
| 20 | MKNK1 | 1.69401081 |
| 21 | NME1 | 1.68199406 |
| 22 | GRK1 | 1.68049696 |
| 23 | NEK1 | 1.65762506 |
| 24 | WNK3 | 1.58272503 |
| 25 | EIF2AK2 | 1.56496382 |
| 26 | FRK | 1.55043088 |
| 27 | TAOK3 | 1.52353144 |
| 28 | OXSR1 | 1.43815616 |
| 29 | TRIM28 | 1.34431717 |
| 30 | BCKDK | 1.27298907 |
| 31 | WNK4 | 1.21931801 |
| 32 | PLK4 | 1.20730309 |
| 33 | STK39 | 1.18653116 |
| 34 | CDC7 | 1.18562851 |
| 35 | ALK | 1.16435908 |
| 36 | TEC | 1.15612260 |
| 37 | ACVR1B | 1.13418756 |
| 38 | TTK | 0.98876058 |
| 39 | PHKG1 | 0.96940998 |
| 40 | PHKG2 | 0.96940998 |
| 41 | MAP4K2 | 0.95212422 |
| 42 | TAF1 | 0.91277887 |
| 43 | PLK2 | 0.90605458 |
| 44 | MAP2K6 | 0.90303413 |
| 45 | PLK1 | 0.88804264 |
| 46 | PINK1 | 0.83983427 |
| 47 | ITK | 0.82021491 |
| 48 | PASK | 0.80669864 |
| 49 | AKT3 | 0.79752994 |
| 50 | IKBKB | 0.79059959 |
| 51 | ERBB3 | 0.74232146 |
| 52 | TGFBR1 | 0.74186165 |
| 53 | INSRR | 0.72281653 |
| 54 | KIT | 0.68248732 |
| 55 | KDR | 0.67330741 |
| 56 | BMPR2 | 0.65761171 |
| 57 | CDK19 | 0.64570827 |
| 58 | ATR | 0.63311888 |
| 59 | MAP3K14 | 0.62724137 |
| 60 | DYRK2 | 0.58700501 |
| 61 | TIE1 | 0.58042464 |
| 62 | DAPK1 | 0.55183308 |
| 63 | STK38L | 0.54114799 |
| 64 | CSNK1G3 | 0.50554886 |
| 65 | CSNK1G1 | 0.49517355 |
| 66 | FES | 0.48623155 |
| 67 | FLT3 | 0.48330503 |
| 68 | AURKB | 0.47451786 |
| 69 | PRKCQ | 0.46959209 |
| 70 | WEE1 | 0.44883624 |
| 71 | CSNK2A2 | 0.43956413 |
| 72 | DAPK2 | 0.43551881 |
| 73 | RPS6KA5 | 0.43306678 |
| 74 | CDK8 | 0.40985764 |
| 75 | IKBKE | 0.40594152 |
| 76 | PIK3CA | 0.40338231 |
| 77 | PIK3CG | 0.40031088 |
| 78 | CSNK2A1 | 0.38617050 |
| 79 | CSNK1A1L | 0.37898882 |
| 80 | STK4 | 0.37850708 |
| 81 | PRKCE | 0.35009989 |
| 82 | CSNK1G2 | 0.34702572 |
| 83 | ATM | 0.34252038 |
| 84 | MAPKAPK5 | 0.33760615 |
| 85 | ADRBK1 | 0.33616064 |
| 86 | SYK | 0.32979552 |
| 87 | MAPK13 | 0.32400000 |
| 88 | LCK | 0.30985325 |
| 89 | MAP4K1 | 0.30257966 |
| 90 | MAP3K4 | 0.29975700 |
| 91 | BCR | 0.28367160 |
| 92 | FGFR1 | 0.26809122 |
| 93 | PRKCG | 0.26359652 |
| 94 | CDK7 | 0.25840402 |
| 95 | RPS6KA4 | 0.25165390 |
| 96 | BTK | 0.24889642 |
| 97 | IGF1R | 0.24525371 |
| 98 | NLK | 0.24190779 |
| 99 | JAK3 | 0.24005170 |
| 100 | STK3 | 0.23652040 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.38203734 |
| 2 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.86819417 |
| 3 | Protein export_Homo sapiens_hsa03060 | 2.82689804 |
| 4 | Asthma_Homo sapiens_hsa05310 | 2.78651289 |
| 5 | Allograft rejection_Homo sapiens_hsa05330 | 2.66727445 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.49116294 |
| 7 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.30169936 |
| 8 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.25714639 |
| 9 | Mismatch repair_Homo sapiens_hsa03430 | 2.25525051 |
| 10 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.21607550 |
| 11 | Homologous recombination_Homo sapiens_hsa03440 | 2.18468205 |
| 12 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.02094778 |
| 13 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.99124814 |
| 14 | Parkinsons disease_Homo sapiens_hsa05012 | 1.98686306 |
| 15 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.97227088 |
| 16 | DNA replication_Homo sapiens_hsa03030 | 1.93000623 |
| 17 | RNA transport_Homo sapiens_hsa03013 | 1.84697132 |
| 18 | RNA degradation_Homo sapiens_hsa03018 | 1.73743952 |
| 19 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.72595011 |
| 20 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.72232675 |
| 21 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.71701510 |
| 22 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.70275219 |
| 23 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.66086905 |
| 24 | Basal transcription factors_Homo sapiens_hsa03022 | 1.62532995 |
| 25 | Ribosome_Homo sapiens_hsa03010 | 1.60911657 |
| 26 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.60479819 |
| 27 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.54283248 |
| 28 | Spliceosome_Homo sapiens_hsa03040 | 1.46886891 |
| 29 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.45322322 |
| 30 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.41868395 |
| 31 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.41734818 |
| 32 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.41139560 |
| 33 | Base excision repair_Homo sapiens_hsa03410 | 1.39635599 |
| 34 | Phototransduction_Homo sapiens_hsa04744 | 1.38822630 |
| 35 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.33788554 |
| 36 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.33108759 |
| 37 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.24399918 |
| 38 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.22198701 |
| 39 | Huntingtons disease_Homo sapiens_hsa05016 | 1.17690051 |
| 40 | Purine metabolism_Homo sapiens_hsa00230 | 1.12456131 |
| 41 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.09044472 |
| 42 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.07469787 |
| 43 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.02872983 |
| 44 | Peroxisome_Homo sapiens_hsa04146 | 1.01303392 |
| 45 | Alzheimers disease_Homo sapiens_hsa05010 | 0.98462237 |
| 46 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.97590697 |
| 47 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.95314058 |
| 48 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.92407810 |
| 49 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.92063941 |
| 50 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.88576638 |
| 51 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.86207942 |
| 52 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.85463544 |
| 53 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.81418157 |
| 54 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.79667591 |
| 55 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.79289741 |
| 56 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.78175323 |
| 57 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.76484106 |
| 58 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.69725766 |
| 59 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.67544281 |
| 60 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.60902465 |
| 61 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.60879461 |
| 62 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.60769508 |
| 63 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.59557705 |
| 64 | Metabolic pathways_Homo sapiens_hsa01100 | 0.57670041 |
| 65 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.57006494 |
| 66 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.56737078 |
| 67 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.53693091 |
| 68 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.53669020 |
| 69 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.51606589 |
| 70 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.51539318 |
| 71 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.51525644 |
| 72 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.50016140 |
| 73 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.49575808 |
| 74 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.49531968 |
| 75 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.49298585 |
| 76 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.45970064 |
| 77 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.45730716 |
| 78 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.44439180 |
| 79 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.43060336 |
| 80 | Measles_Homo sapiens_hsa05162 | 0.41698277 |
| 81 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.41521751 |
| 82 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.41353087 |
| 83 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.40994263 |
| 84 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.40968665 |
| 85 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.37272037 |
| 86 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.36671392 |
| 87 | Olfactory transduction_Homo sapiens_hsa04740 | 0.35991287 |
| 88 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.35693825 |
| 89 | Retinol metabolism_Homo sapiens_hsa00830 | 0.33602481 |
| 90 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.32264332 |
| 91 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.32133713 |
| 92 | Carbon metabolism_Homo sapiens_hsa01200 | 0.31951799 |
| 93 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.31825371 |
| 94 | Cell cycle_Homo sapiens_hsa04110 | 0.31818607 |
| 95 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.31586695 |
| 96 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.31045219 |
| 97 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.28263972 |
| 98 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.28141825 |
| 99 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.28016404 |
| 100 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.24827721 |

