

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | skeletal muscle adaptation (GO:0043501) | 8.69466976 |
| 2 | striated muscle atrophy (GO:0014891) | 8.39921005 |
| 3 | protein K6-linked ubiquitination (GO:0085020) | 7.77630280 |
| 4 | skeletal muscle tissue regeneration (GO:0043403) | 7.52820886 |
| 5 | muscle atrophy (GO:0014889) | 7.29792584 |
| 6 | actin-myosin filament sliding (GO:0033275) | 7.16586822 |
| 7 | muscle filament sliding (GO:0030049) | 7.16586822 |
| 8 | response to muscle activity (GO:0014850) | 6.98869958 |
| 9 | negative regulation of muscle hypertrophy (GO:0014741) | 6.79314613 |
| 10 | regulation of skeletal muscle contraction (GO:0014819) | 6.76494945 |
| 11 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 5.95719866 |
| 12 | actin-mediated cell contraction (GO:0070252) | 5.94793677 |
| 13 | negative regulation of skeletal muscle tissue development (GO:0048642) | 5.46075821 |
| 14 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 5.09267711 |
| 15 | cellular response to dexamethasone stimulus (GO:0071549) | 4.95720054 |
| 16 | response to activity (GO:0014823) | 4.86488510 |
| 17 | response to dexamethasone (GO:0071548) | 4.57658839 |
| 18 | auditory receptor cell differentiation (GO:0042491) | 4.50135367 |
| 19 | actin filament-based movement (GO:0030048) | 4.19685818 |
| 20 | negative regulation of oligodendrocyte differentiation (GO:0048715) | 4.07212196 |
| 21 | positive regulation of action potential (GO:0045760) | 3.91595560 |
| 22 | positive regulation of histone H3-K4 methylation (GO:0051571) | 3.91321383 |
| 23 | cellular ketone body metabolic process (GO:0046950) | 3.75671788 |
| 24 | protein-cofactor linkage (GO:0018065) | 3.72739929 |
| 25 | regulation of regulatory T cell differentiation (GO:0045589) | 3.67385524 |
| 26 | positive regulation of cell cycle G1/S phase transition (GO:1902808) | 3.65241880 |
| 27 | negative regulation of cAMP-mediated signaling (GO:0043951) | 3.64515766 |
| 28 | ketone body metabolic process (GO:1902224) | 3.64288612 |
| 29 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 3.61875074 |
| 30 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 3.57866258 |
| 31 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 3.57866258 |
| 32 | regulation of translation, ncRNA-mediated (GO:0045974) | 3.57866258 |
| 33 | striated muscle adaptation (GO:0014888) | 3.55836061 |
| 34 | regulation of acyl-CoA biosynthetic process (GO:0050812) | 3.55416855 |
| 35 | protein polyglutamylation (GO:0018095) | 3.46911642 |
| 36 | positive regulation of G1/S transition of mitotic cell cycle (GO:1900087) | 3.46637365 |
| 37 | phosphorylated carbohydrate dephosphorylation (GO:0046838) | 3.44301578 |
| 38 | inositol phosphate dephosphorylation (GO:0046855) | 3.44301578 |
| 39 | inositol phosphate catabolic process (GO:0071545) | 3.41506642 |
| 40 | cullin deneddylation (GO:0010388) | 3.40538040 |
| 41 | neural tube formation (GO:0001841) | 3.33505862 |
| 42 | regulation of centriole replication (GO:0046599) | 3.25998956 |
| 43 | regulation of muscle hypertrophy (GO:0014743) | 3.20235551 |
| 44 | response to testosterone (GO:0033574) | 3.19908807 |
| 45 | regulation of relaxation of muscle (GO:1901077) | 3.18656141 |
| 46 | regulation of cofactor metabolic process (GO:0051193) | 3.15933285 |
| 47 | regulation of coenzyme metabolic process (GO:0051196) | 3.15933285 |
| 48 | protein deneddylation (GO:0000338) | 3.11768708 |
| 49 | myotube cell development (GO:0014904) | 3.08063137 |
| 50 | negative regulation of histone acetylation (GO:0035067) | 2.98194986 |
| 51 | muscle organ development (GO:0007517) | 2.97189559 |
| 52 | dendritic spine morphogenesis (GO:0060997) | 2.96807470 |
| 53 | muscle structure development (GO:0061061) | 2.95357109 |
| 54 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.92777240 |
| 55 | postsynaptic membrane organization (GO:0001941) | 2.90016168 |
| 56 | positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:00357 | 2.89564436 |
| 57 | platelet dense granule organization (GO:0060155) | 2.88682406 |
| 58 | cellular response to glucocorticoid stimulus (GO:0071385) | 2.88204824 |
| 59 | regulation of sulfur metabolic process (GO:0042762) | 2.84978376 |
| 60 | negative regulation of fatty acid metabolic process (GO:0045922) | 2.82801614 |
| 61 | positive regulation of interleukin-17 production (GO:0032740) | 2.81532252 |
| 62 | regulation of glucokinase activity (GO:0033131) | 2.80533826 |
| 63 | regulation of hexokinase activity (GO:1903299) | 2.80533826 |
| 64 | tissue regeneration (GO:0042246) | 2.74110078 |
| 65 | negative regulation of organelle assembly (GO:1902116) | 2.73914757 |
| 66 | response to electrical stimulus (GO:0051602) | 2.65760274 |
| 67 | muscle adaptation (GO:0043500) | 2.63748393 |
| 68 | cellular response to corticosteroid stimulus (GO:0071384) | 2.61932388 |
| 69 | regulation of gene expression by genetic imprinting (GO:0006349) | 2.61699627 |
| 70 | protein trimerization (GO:0070206) | 2.61079763 |
| 71 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc | 2.58816724 |
| 72 | glycosphingolipid biosynthetic process (GO:0006688) | 2.58131040 |
| 73 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.57688864 |
| 74 | forebrain neuron differentiation (GO:0021879) | 2.56703980 |
| 75 | negative regulation of fatty acid biosynthetic process (GO:0045717) | 2.56143022 |
| 76 | regulation of action potential (GO:0098900) | 2.55308934 |
| 77 | neuronal action potential propagation (GO:0019227) | 2.54753069 |
| 78 | skeletal muscle contraction (GO:0003009) | 2.53614783 |
| 79 | regulation of DNA methylation (GO:0044030) | 2.49166879 |
| 80 | Golgi to endosome transport (GO:0006895) | 2.49125834 |
| 81 | behavioral response to nicotine (GO:0035095) | 2.47271204 |
| 82 | axoneme assembly (GO:0035082) | 2.46329686 |
| 83 | heparin biosynthetic process (GO:0030210) | 2.43997196 |
| 84 | heparin metabolic process (GO:0030202) | 2.43997196 |
| 85 | genetic imprinting (GO:0071514) | 2.43373266 |
| 86 | hair cell differentiation (GO:0035315) | 2.43286865 |
| 87 | negative regulation of DNA recombination (GO:0045910) | 2.42844354 |
| 88 | negative regulation of peptidyl-lysine acetylation (GO:2000757) | 2.41937688 |
| 89 | regulation of oligodendrocyte differentiation (GO:0048713) | 2.41818520 |
| 90 | regulation of meiosis I (GO:0060631) | 2.41443447 |
| 91 | kynurenine metabolic process (GO:0070189) | 2.41408589 |
| 92 | regulation of transcription involved in cell fate commitment (GO:0060850) | 2.40180908 |
| 93 | positive regulation of dendritic spine development (GO:0060999) | 2.39322350 |
| 94 | nucleobase catabolic process (GO:0046113) | 2.39194368 |
| 95 | male sex determination (GO:0030238) | 2.38275764 |
| 96 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla | 2.36439759 |
| 97 | negative regulation of histone methylation (GO:0031061) | 2.34485680 |
| 98 | regulation of memory T cell differentiation (GO:0043380) | 2.33609317 |
| 99 | cAMP catabolic process (GO:0006198) | 2.32622073 |
| 100 | response to gravity (GO:0009629) | 12.1474577 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VDR_22108803_ChIP-Seq_LS180_Human | 5.06607043 |
| 2 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 5.04067092 |
| 3 | TAF15_26573619_Chip-Seq_HEK293_Human | 4.62443884 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.80394789 |
| 5 | FUS_26573619_Chip-Seq_HEK293_Human | 3.02528483 |
| 6 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.91440305 |
| 7 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.81613310 |
| 8 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.78239616 |
| 9 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.56813236 |
| 10 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.55950699 |
| 11 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.55034330 |
| 12 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.54130661 |
| 13 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.42563304 |
| 14 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.37698786 |
| 15 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.33441264 |
| 16 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.30384285 |
| 17 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.20326426 |
| 18 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.09560164 |
| 19 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.08165260 |
| 20 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.87692102 |
| 21 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.86412419 |
| 22 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.85349398 |
| 23 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.82945040 |
| 24 | P300_19829295_ChIP-Seq_ESCs_Human | 1.77838796 |
| 25 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.74701038 |
| 26 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.70232430 |
| 27 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.70085604 |
| 28 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.65436799 |
| 29 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.61676377 |
| 30 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.57778177 |
| 31 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.57469539 |
| 32 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.56647280 |
| 33 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.56621457 |
| 34 | EWS_26573619_Chip-Seq_HEK293_Human | 1.55211500 |
| 35 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.54774636 |
| 36 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.52728270 |
| 37 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.52267501 |
| 38 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.45693965 |
| 39 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.43864654 |
| 40 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.43290380 |
| 41 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.40169704 |
| 42 | STAT3_23295773_ChIP-Seq_U87_Human | 1.39724904 |
| 43 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.38775257 |
| 44 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.36905126 |
| 45 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.32705204 |
| 46 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.32311963 |
| 47 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.29438568 |
| 48 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.29073931 |
| 49 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.29073931 |
| 50 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.28885996 |
| 51 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.27279416 |
| 52 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.24947741 |
| 53 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.24454822 |
| 54 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.23223576 |
| 55 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.23165054 |
| 56 | SOX9_26525672_Chip-Seq_HEART_Mouse | 1.22766380 |
| 57 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.22222736 |
| 58 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.19504194 |
| 59 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.19278793 |
| 60 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.18156992 |
| 61 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.17835045 |
| 62 | KDM2B_26808549_Chip-Seq_REH_Human | 1.17356332 |
| 63 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.17249051 |
| 64 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.16154705 |
| 65 | TCF4_23295773_ChIP-Seq_U87_Human | 1.15918105 |
| 66 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.14847013 |
| 67 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.14660221 |
| 68 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.14523552 |
| 69 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.13890505 |
| 70 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.13367739 |
| 71 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.13064974 |
| 72 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.12792586 |
| 73 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.10175784 |
| 74 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.09740803 |
| 75 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.09591841 |
| 76 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.08278225 |
| 77 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.06468297 |
| 78 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.03998597 |
| 79 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.02765370 |
| 80 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.02417277 |
| 81 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.02290916 |
| 82 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.01976196 |
| 83 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.01972605 |
| 84 | AR_25329375_ChIP-Seq_VCAP_Human | 1.01360904 |
| 85 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.01292865 |
| 86 | GATA1_22025678_ChIP-Seq_K562_Human | 1.00222992 |
| 87 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.00220289 |
| 88 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.99854767 |
| 89 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.98796353 |
| 90 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.97769154 |
| 91 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.97445079 |
| 92 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.96179016 |
| 93 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.95824598 |
| 94 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.94733851 |
| 95 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 0.94609766 |
| 96 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.94016463 |
| 97 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 0.93974993 |
| 98 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.93872973 |
| 99 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.93803642 |
| 100 | NCOR_22424771_ChIP-Seq_293T_Human | 0.93291602 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000372_irregular_coat_pigmentation | 5.63648231 |
| 2 | MP0004145_abnormal_muscle_electrophysio | 3.96458650 |
| 3 | MP0002938_white_spotting | 3.45008354 |
| 4 | MP0000747_muscle_weakness | 3.31891779 |
| 5 | MP0005083_abnormal_biliary_tract | 3.28988823 |
| 6 | MP0004270_analgesia | 3.23661885 |
| 7 | MP0004036_abnormal_muscle_relaxation | 2.97149040 |
| 8 | MP0000749_muscle_degeneration | 2.61244479 |
| 9 | MP0008877_abnormal_DNA_methylation | 2.55348547 |
| 10 | MP0005379_endocrine/exocrine_gland_phen | 2.37218137 |
| 11 | MP0002163_abnormal_gland_morphology | 2.35687927 |
| 12 | MP0002108_abnormal_muscle_morphology | 2.35632260 |
| 13 | MP0002269_muscular_atrophy | 2.26473335 |
| 14 | MP0000759_abnormal_skeletal_muscle | 2.18261165 |
| 15 | MP0002106_abnormal_muscle_physiology | 2.07483476 |
| 16 | MP0000566_synostosis | 2.05131161 |
| 17 | MP0005620_abnormal_muscle_contractility | 2.01298919 |
| 18 | MP0003787_abnormal_imprinting | 1.96889052 |
| 19 | MP0000049_abnormal_middle_ear | 1.96376184 |
| 20 | MP0002095_abnormal_skin_pigmentation | 1.92973730 |
| 21 | MP0003121_genomic_imprinting | 1.84179164 |
| 22 | MP0005174_abnormal_tail_pigmentation | 1.77702729 |
| 23 | MP0005369_muscle_phenotype | 1.73757731 |
| 24 | MP0009780_abnormal_chondrocyte_physiolo | 1.69321024 |
| 25 | MP0008789_abnormal_olfactory_epithelium | 1.67911108 |
| 26 | MP0006072_abnormal_retinal_apoptosis | 1.66098430 |
| 27 | MP0004885_abnormal_endolymph | 1.65169240 |
| 28 | MP0000750_abnormal_muscle_regeneration | 1.61948145 |
| 29 | MP0003786_premature_aging | 1.60922133 |
| 30 | MP0001984_abnormal_olfaction | 1.59018168 |
| 31 | MP0002089_abnormal_postnatal_growth/wei | 1.58308230 |
| 32 | MP0002837_dystrophic_cardiac_calcinosis | 1.56449986 |
| 33 | MP0003122_maternal_imprinting | 1.55792293 |
| 34 | MP0002102_abnormal_ear_morphology | 1.55219429 |
| 35 | MP0005646_abnormal_pituitary_gland | 1.54298616 |
| 36 | MP0006292_abnormal_olfactory_placode | 1.53979618 |
| 37 | MP0004087_abnormal_muscle_fiber | 1.52352872 |
| 38 | MP0003123_paternal_imprinting | 1.52224292 |
| 39 | MP0002638_abnormal_pupillary_reflex | 1.44376813 |
| 40 | MP0005248_abnormal_Harderian_gland | 1.37748437 |
| 41 | MP0000516_abnormal_urinary_system | 1.34248573 |
| 42 | MP0005367_renal/urinary_system_phenotyp | 1.34248573 |
| 43 | MP0002736_abnormal_nociception_after | 1.33314968 |
| 44 | MP0003755_abnormal_palate_morphology | 1.24582359 |
| 45 | MP0001270_distended_abdomen | 1.24472890 |
| 46 | MP0003938_abnormal_ear_development | 1.22536466 |
| 47 | MP0003937_abnormal_limbs/digits/tail_de | 1.22151915 |
| 48 | MP0004484_altered_response_of | 1.16878260 |
| 49 | MP0005645_abnormal_hypothalamus_physiol | 1.15650991 |
| 50 | MP0010307_abnormal_tumor_latency | 1.13438645 |
| 51 | MP0002254_reproductive_system_inflammat | 1.13353966 |
| 52 | MP0001968_abnormal_touch/_nociception | 1.13305256 |
| 53 | MP0008995_early_reproductive_senescence | 1.10903938 |
| 54 | MP0000427_abnormal_hair_cycle | 1.08553972 |
| 55 | MP0005253_abnormal_eye_physiology | 1.08447750 |
| 56 | MP0001963_abnormal_hearing_physiology | 1.07890573 |
| 57 | MP0000751_myopathy | 1.06567415 |
| 58 | MP0002896_abnormal_bone_mineralization | 1.05623130 |
| 59 | MP0005551_abnormal_eye_electrophysiolog | 1.02536092 |
| 60 | MP0002277_abnormal_respiratory_mucosa | 1.00409040 |
| 61 | MP0001346_abnormal_lacrimal_gland | 0.99382797 |
| 62 | MP0000733_abnormal_muscle_development | 0.98015239 |
| 63 | MP0000013_abnormal_adipose_tissue | 0.96902283 |
| 64 | MP0003959_abnormal_lean_body | 0.96628533 |
| 65 | MP0004215_abnormal_myocardial_fiber | 0.96124433 |
| 66 | MP0004142_abnormal_muscle_tone | 0.90618158 |
| 67 | MP0003646_muscle_fatigue | 0.87182336 |
| 68 | MP0001502_abnormal_circadian_rhythm | 0.85461739 |
| 69 | MP0003195_calcinosis | 0.85318308 |
| 70 | MP0004084_abnormal_cardiac_muscle | 0.84453818 |
| 71 | MP0002751_abnormal_autonomic_nervous | 0.83942138 |
| 72 | MP0004043_abnormal_pH_regulation | 0.82949245 |
| 73 | MP0000465_gastrointestinal_hemorrhage | 0.82078897 |
| 74 | MP0005499_abnormal_olfactory_system | 0.81556866 |
| 75 | MP0005394_taste/olfaction_phenotype | 0.81556866 |
| 76 | MP0000631_abnormal_neuroendocrine_gland | 0.80847407 |
| 77 | MP0009745_abnormal_behavioral_response | 0.79632201 |
| 78 | MP0003950_abnormal_plasma_membrane | 0.78956527 |
| 79 | MP0002734_abnormal_mechanical_nocicepti | 0.78133257 |
| 80 | MP0003880_abnormal_central_pattern | 0.77386504 |
| 81 | MP0002282_abnormal_trachea_morphology | 0.72553808 |
| 82 | MP0001486_abnormal_startle_reflex | 0.71218249 |
| 83 | MP0003045_fibrosis | 0.71131409 |
| 84 | MP0005171_absent_coat_pigmentation | 0.71042105 |
| 85 | MP0002557_abnormal_social/conspecific_i | 0.70813687 |
| 86 | MP0006276_abnormal_autonomic_nervous | 0.69973464 |
| 87 | MP0002928_abnormal_bile_duct | 0.69906225 |
| 88 | MP0005647_abnormal_sex_gland | 0.69352066 |
| 89 | MP0009046_muscle_twitch | 0.68692294 |
| 90 | MP0000639_abnormal_adrenal_gland | 0.68127913 |
| 91 | MP0002075_abnormal_coat/hair_pigmentati | 0.64646593 |
| 92 | MP0002233_abnormal_nose_morphology | 0.64645634 |
| 93 | MP0001501_abnormal_sleep_pattern | 0.63837369 |
| 94 | MP0000604_amyloidosis | 0.63669245 |
| 95 | MP0001661_extended_life_span | 0.63594147 |
| 96 | MP0004197_abnormal_fetal_growth/weight/ | 0.62227649 |
| 97 | MP0002115_abnormal_skeleton_extremities | 0.60745430 |
| 98 | MP0000026_abnormal_inner_ear | 0.60224240 |
| 99 | MP0002184_abnormal_innervation | 0.59542552 |
| 100 | MP0002876_abnormal_thyroid_physiology | 0.58531143 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Palpebral edema (HP:0100540) | 7.53441846 |
| 2 | Nemaline bodies (HP:0003798) | 5.65452725 |
| 3 | Distal arthrogryposis (HP:0005684) | 5.30358648 |
| 4 | Mask-like facies (HP:0000298) | 4.67972991 |
| 5 | Round ear (HP:0100830) | 4.61624224 |
| 6 | Muscle fiber inclusion bodies (HP:0100299) | 4.45703026 |
| 7 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 4.42594863 |
| 8 | Exercise-induced myalgia (HP:0003738) | 4.37757741 |
| 9 | Absent phalangeal crease (HP:0006109) | 4.26649022 |
| 10 | Calcaneovalgus deformity (HP:0001848) | 3.77047325 |
| 11 | Ulnar deviation of the wrist (HP:0003049) | 3.71798361 |
| 12 | Facial edema (HP:0000282) | 3.70767461 |
| 13 | Abnormal finger flexion creases (HP:0006143) | 3.69397264 |
| 14 | Periorbital edema (HP:0100539) | 3.69180694 |
| 15 | 3-Methylglutaconic aciduria (HP:0003535) | 3.46564461 |
| 16 | Hyperkalemia (HP:0002153) | 3.32318910 |
| 17 | Deformed tarsal bones (HP:0008119) | 3.27674485 |
| 18 | Neoplasm of the heart (HP:0100544) | 3.07437347 |
| 19 | Fibular aplasia (HP:0002990) | 2.98993810 |
| 20 | Difficulty running (HP:0009046) | 2.85373875 |
| 21 | Neoplasm of the adrenal cortex (HP:0100641) | 2.77589681 |
| 22 | Exercise-induced muscle cramps (HP:0003710) | 2.76230540 |
| 23 | Type 1 muscle fiber predominance (HP:0003803) | 2.64352669 |
| 24 | Renal dysplasia (HP:0000110) | 2.61429025 |
| 25 | Hepatoblastoma (HP:0002884) | 2.49566307 |
| 26 | Nephronophthisis (HP:0000090) | 2.48743613 |
| 27 | Oligodactyly (hands) (HP:0001180) | 2.47456061 |
| 28 | Pancreatic fibrosis (HP:0100732) | 2.45703912 |
| 29 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.40749494 |
| 30 | Congenital stationary night blindness (HP:0007642) | 2.38519316 |
| 31 | Metaphyseal dysplasia (HP:0100255) | 2.38363603 |
| 32 | Muscle hypertrophy of the lower extremities (HP:0008968) | 2.37817741 |
| 33 | Decreased circulating renin level (HP:0003351) | 2.37750276 |
| 34 | Volvulus (HP:0002580) | 2.37415570 |
| 35 | Delayed CNS myelination (HP:0002188) | 2.33489305 |
| 36 | Pancreatic cysts (HP:0001737) | 2.31190551 |
| 37 | True hermaphroditism (HP:0010459) | 2.28169102 |
| 38 | Adrenal hypoplasia (HP:0000835) | 2.27891409 |
| 39 | Nonprogressive disorder (HP:0003680) | 2.24809570 |
| 40 | Menstrual irregularities (HP:0000858) | 2.22993674 |
| 41 | Pendular nystagmus (HP:0012043) | 2.22572147 |
| 42 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.17494967 |
| 43 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.15884457 |
| 44 | Intestinal atresia (HP:0011100) | 2.13946284 |
| 45 | Absent speech (HP:0001344) | 2.08268690 |
| 46 | Type II lissencephaly (HP:0007260) | 2.07662284 |
| 47 | Poor speech (HP:0002465) | 2.06743563 |
| 48 | Keratoconus (HP:0000563) | 2.05774898 |
| 49 | Increased corneal curvature (HP:0100692) | 2.05774898 |
| 50 | Myotonia (HP:0002486) | 2.04097812 |
| 51 | Recurrent corneal erosions (HP:0000495) | 2.01749804 |
| 52 | Chronic hepatic failure (HP:0100626) | 2.00738041 |
| 53 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 2.00093210 |
| 54 | Metatarsus adductus (HP:0001840) | 1.99374163 |
| 55 | Aqueductal stenosis (HP:0002410) | 1.98129309 |
| 56 | 2-3 toe syndactyly (HP:0004691) | 1.97813251 |
| 57 | Attenuation of retinal blood vessels (HP:0007843) | 1.97636916 |
| 58 | Oligodactyly (HP:0012165) | 1.96812309 |
| 59 | Parakeratosis (HP:0001036) | 1.90807925 |
| 60 | Abnormality of potassium homeostasis (HP:0011042) | 1.89698910 |
| 61 | Abnormality of the renal medulla (HP:0100957) | 1.89495569 |
| 62 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 1.89249569 |
| 63 | Hypoplasia of the fovea (HP:0007750) | 1.89249569 |
| 64 | Hypoplastic ischia (HP:0003175) | 1.88447140 |
| 65 | Abolished electroretinogram (ERG) (HP:0000550) | 1.88439735 |
| 66 | Diastasis recti (HP:0001540) | 1.87871247 |
| 67 | Cerebellar dysplasia (HP:0007033) | 1.86860572 |
| 68 | Breast carcinoma (HP:0003002) | 1.85500695 |
| 69 | Action tremor (HP:0002345) | 1.85448552 |
| 70 | Gonadotropin excess (HP:0000837) | 1.82604028 |
| 71 | Cortical dysplasia (HP:0002539) | 1.82458513 |
| 72 | Alopecia of scalp (HP:0002293) | 1.81830221 |
| 73 | Myopathic facies (HP:0002058) | 1.80906383 |
| 74 | Gout (HP:0001997) | 1.80068745 |
| 75 | Drooling (HP:0002307) | 1.79607674 |
| 76 | Polydipsia (HP:0001959) | 1.79054380 |
| 77 | Abnormal drinking behavior (HP:0030082) | 1.79054380 |
| 78 | Chorioretinal atrophy (HP:0000533) | 1.78759808 |
| 79 | Hypoplastic iliac wings (HP:0002866) | 1.75398352 |
| 80 | Abnormality of the renal cortex (HP:0011035) | 1.74487499 |
| 81 | Depressed nasal tip (HP:0000437) | 1.73986935 |
| 82 | Pachygyria (HP:0001302) | 1.73854602 |
| 83 | Abnormality of the labia minora (HP:0012880) | 1.72530594 |
| 84 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.72193867 |
| 85 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.69505166 |
| 86 | Increased purine levels (HP:0004368) | 1.69318572 |
| 87 | Hyperuricemia (HP:0002149) | 1.69318572 |
| 88 | Myoglobinuria (HP:0002913) | 1.69226787 |
| 89 | Abnormality of the calf musculature (HP:0001430) | 1.69045280 |
| 90 | Macroorchidism (HP:0000053) | 1.67667367 |
| 91 | Abnormality of the ischium (HP:0003174) | 1.66793312 |
| 92 | Short phalanx of the thumb (HP:0009660) | 1.66763620 |
| 93 | Down-sloping shoulders (HP:0200021) | 1.66394219 |
| 94 | Steppage gait (HP:0003376) | 1.66073395 |
| 95 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 1.63257480 |
| 96 | Growth hormone deficiency (HP:0000824) | 1.63224447 |
| 97 | Widely spaced teeth (HP:0000687) | 1.63090440 |
| 98 | Blue irides (HP:0000635) | 1.61517354 |
| 99 | Neoplasm of the adrenal gland (HP:0100631) | 1.60831069 |
| 100 | Excessive salivation (HP:0003781) | 1.60465516 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FRK | 4.43389899 |
| 2 | BRD4 | 3.94966616 |
| 3 | PHKG2 | 3.59379585 |
| 4 | PHKG1 | 3.59379585 |
| 5 | NEK1 | 3.57981536 |
| 6 | TIE1 | 2.90487122 |
| 7 | OBSCN | 2.83541652 |
| 8 | WNK4 | 2.64403944 |
| 9 | MAP3K4 | 2.58969222 |
| 10 | MAPK13 | 2.55181091 |
| 11 | NUAK1 | 2.32132026 |
| 12 | WNK3 | 2.18788268 |
| 13 | FGFR2 | 2.08999335 |
| 14 | PRKD3 | 1.97745675 |
| 15 | EIF2AK3 | 1.97465047 |
| 16 | CDK19 | 1.97213918 |
| 17 | MST4 | 1.83227003 |
| 18 | CCNB1 | 1.78287708 |
| 19 | CASK | 1.64413834 |
| 20 | DAPK2 | 1.63424602 |
| 21 | PLK2 | 1.62129943 |
| 22 | IRAK1 | 1.53358891 |
| 23 | CDC7 | 1.47560850 |
| 24 | MAP4K2 | 1.42596168 |
| 25 | IRAK4 | 1.36763736 |
| 26 | LIMK1 | 1.28745247 |
| 27 | ADRBK2 | 1.28322468 |
| 28 | PINK1 | 1.28090866 |
| 29 | WNK1 | 1.27776316 |
| 30 | PLK3 | 1.24082305 |
| 31 | RPS6KA4 | 1.13991867 |
| 32 | GRK5 | 1.12288164 |
| 33 | SRPK1 | 1.11641707 |
| 34 | GRK1 | 1.10728358 |
| 35 | SCYL2 | 1.10703951 |
| 36 | CAMKK2 | 1.08825017 |
| 37 | VRK2 | 1.07667649 |
| 38 | MAP2K7 | 1.05377330 |
| 39 | ZAK | 1.00436761 |
| 40 | TAF1 | 1.00412462 |
| 41 | ERBB3 | 0.95765398 |
| 42 | EIF2AK1 | 0.95589902 |
| 43 | EIF2AK2 | 0.92357590 |
| 44 | PRKCE | 0.92299259 |
| 45 | CHEK2 | 0.85152762 |
| 46 | TEC | 0.84417105 |
| 47 | CAMK2G | 0.83432099 |
| 48 | CSNK1A1L | 0.77266505 |
| 49 | DYRK2 | 0.71093127 |
| 50 | TYRO3 | 0.69616155 |
| 51 | BUB1 | 0.68775671 |
| 52 | DAPK1 | 0.64301558 |
| 53 | PIK3CA | 0.64126564 |
| 54 | CSNK1G1 | 0.63934393 |
| 55 | PLK1 | 0.63788054 |
| 56 | MARK1 | 0.63039965 |
| 57 | BCKDK | 0.59985288 |
| 58 | PLK4 | 0.59834391 |
| 59 | CSNK1G3 | 0.58336558 |
| 60 | TXK | 0.57906843 |
| 61 | CSNK1G2 | 0.57244583 |
| 62 | ATR | 0.57066381 |
| 63 | PRKD2 | 0.56696721 |
| 64 | VRK1 | 0.55858685 |
| 65 | RPS6KA5 | 0.53517503 |
| 66 | ATM | 0.51751681 |
| 67 | STK39 | 0.50824409 |
| 68 | TRPM7 | 0.50739669 |
| 69 | PKN1 | 0.50433548 |
| 70 | TAOK1 | 0.49741810 |
| 71 | MINK1 | 0.48319591 |
| 72 | MARK3 | 0.47580587 |
| 73 | PIK3CG | 0.47365219 |
| 74 | MAPK7 | 0.46545606 |
| 75 | CAMK1D | 0.45672750 |
| 76 | PRKG1 | 0.44162955 |
| 77 | DYRK1B | 0.43687341 |
| 78 | PRKACA | 0.43047307 |
| 79 | FGFR3 | 0.41728599 |
| 80 | CAMK4 | 0.40751692 |
| 81 | AURKA | 0.36175942 |
| 82 | DYRK1A | 0.35551195 |
| 83 | BCR | 0.34644743 |
| 84 | PRKACB | 0.32189216 |
| 85 | DMPK | 0.31592202 |
| 86 | CAMK2D | 0.31502967 |
| 87 | NTRK2 | 0.31399658 |
| 88 | CAMK2A | 0.29979326 |
| 89 | SGK1 | 0.29006892 |
| 90 | AURKB | 0.28086960 |
| 91 | BMPR1B | 0.27268185 |
| 92 | CAMK1 | 0.26569959 |
| 93 | ICK | 0.25799264 |
| 94 | EGFR | 0.25135572 |
| 95 | ROCK1 | 0.24268121 |
| 96 | CDK4 | 0.23565136 |
| 97 | INSRR | 0.22309854 |
| 98 | PTK2B | 0.21933317 |
| 99 | PRKCG | 0.21379260 |
| 100 | TRIM28 | 0.20810969 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 5.02046414 |
| 2 | Tight junction_Homo sapiens_hsa04530 | 3.16143323 |
| 3 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.84406423 |
| 4 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.54531209 |
| 5 | Phototransduction_Homo sapiens_hsa04744 | 2.31871447 |
| 6 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 2.23862453 |
| 7 | Circadian rhythm_Homo sapiens_hsa04710 | 2.16618960 |
| 8 | Regulation of autophagy_Homo sapiens_hsa04140 | 2.02519858 |
| 9 | Peroxisome_Homo sapiens_hsa04146 | 1.92025534 |
| 10 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.90748253 |
| 11 | Circadian entrainment_Homo sapiens_hsa04713 | 1.86870690 |
| 12 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.78230753 |
| 13 | Insulin secretion_Homo sapiens_hsa04911 | 1.77800712 |
| 14 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.77703888 |
| 15 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.76520619 |
| 16 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.72416332 |
| 17 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.67475637 |
| 18 | Morphine addiction_Homo sapiens_hsa05032 | 1.66347158 |
| 19 | Protein export_Homo sapiens_hsa03060 | 1.61327713 |
| 20 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.61263441 |
| 21 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.56331497 |
| 22 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.56194578 |
| 23 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.53230620 |
| 24 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.42830004 |
| 25 | Homologous recombination_Homo sapiens_hsa03440 | 1.42759119 |
| 26 | Basal transcription factors_Homo sapiens_hsa03022 | 1.41680763 |
| 27 | GABAergic synapse_Homo sapiens_hsa04727 | 1.41409702 |
| 28 | Renin secretion_Homo sapiens_hsa04924 | 1.37063968 |
| 29 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.32537586 |
| 30 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.28316406 |
| 31 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.26778525 |
| 32 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.25912477 |
| 33 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.23962011 |
| 34 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.22144016 |
| 35 | Nicotine addiction_Homo sapiens_hsa05033 | 1.21396172 |
| 36 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.20575770 |
| 37 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.20377895 |
| 38 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.18773200 |
| 39 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.13363568 |
| 40 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.12310730 |
| 41 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.12069423 |
| 42 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.10636043 |
| 43 | Olfactory transduction_Homo sapiens_hsa04740 | 1.09150313 |
| 44 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.08294951 |
| 45 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.06011839 |
| 46 | RNA degradation_Homo sapiens_hsa03018 | 0.99818120 |
| 47 | RNA polymerase_Homo sapiens_hsa03020 | 0.98915136 |
| 48 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.98591289 |
| 49 | Proteasome_Homo sapiens_hsa03050 | 0.98283468 |
| 50 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.95932631 |
| 51 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.95203876 |
| 52 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.93873641 |
| 53 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.90048505 |
| 54 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.89769598 |
| 55 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.89288737 |
| 56 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.89147907 |
| 57 | Spliceosome_Homo sapiens_hsa03040 | 0.88269989 |
| 58 | Parkinsons disease_Homo sapiens_hsa05012 | 0.87642873 |
| 59 | Salivary secretion_Homo sapiens_hsa04970 | 0.86666278 |
| 60 | Purine metabolism_Homo sapiens_hsa00230 | 0.85516440 |
| 61 | Taste transduction_Homo sapiens_hsa04742 | 0.84911975 |
| 62 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.81985535 |
| 63 | Alzheimers disease_Homo sapiens_hsa05010 | 0.79633908 |
| 64 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.77129016 |
| 65 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.74717574 |
| 66 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.71730167 |
| 67 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.70883411 |
| 68 | Long-term depression_Homo sapiens_hsa04730 | 0.69854723 |
| 69 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.65790832 |
| 70 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.65627403 |
| 71 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.62455478 |
| 72 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.59081508 |
| 73 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.58798987 |
| 74 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.54833708 |
| 75 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.51302306 |
| 76 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.50312774 |
| 77 | RNA transport_Homo sapiens_hsa03013 | 0.47874435 |
| 78 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.47782953 |
| 79 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.46999515 |
| 80 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.46926334 |
| 81 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.46536733 |
| 82 | Alcoholism_Homo sapiens_hsa05034 | 0.43738877 |
| 83 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.42365336 |
| 84 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.42136476 |
| 85 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.41465698 |
| 86 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.41086817 |
| 87 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.39028538 |
| 88 | Asthma_Homo sapiens_hsa05310 | 0.38496126 |
| 89 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.37685268 |
| 90 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.37502827 |
| 91 | Huntingtons disease_Homo sapiens_hsa05016 | 0.37329048 |
| 92 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.33694819 |
| 93 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.33399255 |
| 94 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.33140608 |
| 95 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.32115846 |
| 96 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.30097316 |
| 97 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.28776474 |
| 98 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.27775455 |
| 99 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.27556260 |
| 100 | Retinol metabolism_Homo sapiens_hsa00830 | 0.27396576 |

