

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | proteasome assembly (GO:0043248) | 5.64045728 |
| 2 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.83473657 |
| 3 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.82370457 |
| 4 | DNA deamination (GO:0045006) | 4.72499190 |
| 5 | rRNA modification (GO:0000154) | 4.70777942 |
| 6 | ATP synthesis coupled proton transport (GO:0015986) | 4.56911576 |
| 7 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.56911576 |
| 8 | chaperone-mediated protein transport (GO:0072321) | 4.28262557 |
| 9 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.21840016 |
| 10 | protein neddylation (GO:0045116) | 4.15102105 |
| 11 | rRNA methylation (GO:0031167) | 4.13052034 |
| 12 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 4.06100912 |
| 13 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 4.05659700 |
| 14 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.96276304 |
| 15 | ribosome assembly (GO:0042255) | 3.86964163 |
| 16 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.83215642 |
| 17 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.83215642 |
| 18 | NADH dehydrogenase complex assembly (GO:0010257) | 3.83215642 |
| 19 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.82599221 |
| 20 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.82157735 |
| 21 | chromatin remodeling at centromere (GO:0031055) | 3.80423899 |
| 22 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.79102404 |
| 23 | CENP-A containing nucleosome assembly (GO:0034080) | 3.75799709 |
| 24 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.75595782 |
| 25 | negative regulation of ligase activity (GO:0051352) | 3.75595782 |
| 26 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.75438931 |
| 27 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.75438931 |
| 28 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.72719649 |
| 29 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.71669625 |
| 30 | protein complex biogenesis (GO:0070271) | 3.69825101 |
| 31 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.69034963 |
| 32 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.69034963 |
| 33 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.69034963 |
| 34 | pseudouridine synthesis (GO:0001522) | 3.67340030 |
| 35 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.66061803 |
| 36 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.65583825 |
| 37 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.65583825 |
| 38 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.58620551 |
| 39 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.58308062 |
| 40 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.58308062 |
| 41 | isotype switching (GO:0045190) | 3.58308062 |
| 42 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.55053433 |
| 43 | regulation of chronic inflammatory response (GO:0002676) | 3.53050820 |
| 44 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.51978968 |
| 45 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.51978968 |
| 46 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.50124450 |
| 47 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.46757050 |
| 48 | IMP biosynthetic process (GO:0006188) | 3.46622087 |
| 49 | ribosomal large subunit biogenesis (GO:0042273) | 3.40569720 |
| 50 | DNA double-strand break processing (GO:0000729) | 3.35451222 |
| 51 | rRNA processing (GO:0006364) | 3.33546740 |
| 52 | termination of RNA polymerase III transcription (GO:0006386) | 3.27608652 |
| 53 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.27608652 |
| 54 | spliceosomal snRNP assembly (GO:0000387) | 3.26646957 |
| 55 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.25978910 |
| 56 | rRNA metabolic process (GO:0016072) | 3.23587176 |
| 57 | viral mRNA export from host cell nucleus (GO:0046784) | 3.20123607 |
| 58 | protein-cofactor linkage (GO:0018065) | 3.19053364 |
| 59 | maturation of 5.8S rRNA (GO:0000460) | 3.18152756 |
| 60 | respiratory electron transport chain (GO:0022904) | 3.17982772 |
| 61 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.17809016 |
| 62 | histone exchange (GO:0043486) | 3.17052200 |
| 63 | electron transport chain (GO:0022900) | 3.16219692 |
| 64 | positive regulation of ligase activity (GO:0051351) | 3.14873789 |
| 65 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.14641375 |
| 66 | protein targeting to mitochondrion (GO:0006626) | 3.13793395 |
| 67 | IMP metabolic process (GO:0046040) | 3.13643114 |
| 68 | respiratory chain complex IV assembly (GO:0008535) | 3.12878883 |
| 69 | cullin deneddylation (GO:0010388) | 3.12332533 |
| 70 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.09345782 |
| 71 | maturation of SSU-rRNA (GO:0030490) | 3.07938438 |
| 72 | pteridine-containing compound biosynthetic process (GO:0042559) | 3.01693858 |
| 73 | GTP biosynthetic process (GO:0006183) | 3.01021672 |
| 74 | ribosome biogenesis (GO:0042254) | 3.00895530 |
| 75 | termination of RNA polymerase I transcription (GO:0006363) | 3.00519490 |
| 76 | purine nucleobase biosynthetic process (GO:0009113) | 3.00296150 |
| 77 | inner mitochondrial membrane organization (GO:0007007) | 2.99852679 |
| 78 | tRNA processing (GO:0008033) | 2.99564771 |
| 79 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.97905948 |
| 80 | protein localization to mitochondrion (GO:0070585) | 2.95470305 |
| 81 | translation (GO:0006412) | 2.94668355 |
| 82 | cellular component biogenesis (GO:0044085) | 2.90712467 |
| 83 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.89959162 |
| 84 | ribosomal small subunit assembly (GO:0000028) | 2.89770169 |
| 85 | nucleobase biosynthetic process (GO:0046112) | 2.89492302 |
| 86 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.89145325 |
| 87 | regulation of immunoglobulin secretion (GO:0051023) | 2.88989289 |
| 88 | DNA replication checkpoint (GO:0000076) | 2.88705744 |
| 89 | establishment of protein localization to mitochondrion (GO:0072655) | 2.88433036 |
| 90 | tRNA metabolic process (GO:0006399) | 2.88124846 |
| 91 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.85193382 |
| 92 | intracellular protein transmembrane import (GO:0044743) | 2.84856137 |
| 93 | histone mRNA metabolic process (GO:0008334) | 2.84333785 |
| 94 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.84082387 |
| 95 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.84031935 |
| 96 | formation of translation preinitiation complex (GO:0001731) | 2.83971070 |
| 97 | regulation of cellular amine metabolic process (GO:0033238) | 2.83938140 |
| 98 | mitochondrial RNA metabolic process (GO:0000959) | 2.83366093 |
| 99 | ncRNA metabolic process (GO:0034660) | 2.83242022 |
| 100 | protein deneddylation (GO:0000338) | 2.80109972 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.30915002 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.97869801 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.66714431 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.36719607 |
| 5 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.33186096 |
| 6 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.26319044 |
| 7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.17803949 |
| 8 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.09510117 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.96905693 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.95240481 |
| 11 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.80072408 |
| 12 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.67317229 |
| 13 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.65237696 |
| 14 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.63171094 |
| 15 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.62404607 |
| 16 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.62124060 |
| 17 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.62116315 |
| 18 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.53934487 |
| 19 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.40585249 |
| 20 | VDR_22108803_ChIP-Seq_LS180_Human | 2.28099565 |
| 21 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.15253870 |
| 22 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.05553814 |
| 23 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.02026367 |
| 24 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.01050633 |
| 25 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.98354853 |
| 26 | EWS_26573619_Chip-Seq_HEK293_Human | 1.91438623 |
| 27 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.89860013 |
| 28 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.88808111 |
| 29 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.87381638 |
| 30 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.80071538 |
| 31 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.79015320 |
| 32 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.76898282 |
| 33 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.74284287 |
| 34 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.67502625 |
| 35 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.64748872 |
| 36 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.63290549 |
| 37 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.59097431 |
| 38 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.58139710 |
| 39 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.56369953 |
| 40 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.56181027 |
| 41 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.54726400 |
| 42 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.54257564 |
| 43 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.53024953 |
| 44 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.49869728 |
| 45 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.47167785 |
| 46 | FUS_26573619_Chip-Seq_HEK293_Human | 1.46927941 |
| 47 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.45852641 |
| 48 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.43295716 |
| 49 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.35607965 |
| 50 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.35606269 |
| 51 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.34794629 |
| 52 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.30800607 |
| 53 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.27864347 |
| 54 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.25690919 |
| 55 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.24117413 |
| 56 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.24060862 |
| 57 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.24004674 |
| 58 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.21406133 |
| 59 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.21225671 |
| 60 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.20666560 |
| 61 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.20383338 |
| 62 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.17612560 |
| 63 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.16816502 |
| 64 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.15694704 |
| 65 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.11353237 |
| 66 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.08921557 |
| 67 | P300_19829295_ChIP-Seq_ESCs_Human | 1.07760434 |
| 68 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.05924795 |
| 69 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.03073072 |
| 70 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.03073072 |
| 71 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.02613127 |
| 72 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.00425258 |
| 73 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.00343893 |
| 74 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.99923792 |
| 75 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.99923792 |
| 76 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.99095048 |
| 77 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.97715980 |
| 78 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.96224753 |
| 79 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.95258959 |
| 80 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.95128784 |
| 81 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.94574372 |
| 82 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 0.94158946 |
| 83 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.93156571 |
| 84 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.92086242 |
| 85 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.91984966 |
| 86 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.88530715 |
| 87 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.87360336 |
| 88 | AR_21909140_ChIP-Seq_LNCAP_Human | 0.87237552 |
| 89 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.84486603 |
| 90 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.82778836 |
| 91 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.82455656 |
| 92 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.82296619 |
| 93 | AR_20517297_ChIP-Seq_VCAP_Human | 0.81181165 |
| 94 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.80832566 |
| 95 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.80643972 |
| 96 | GATA3_26560356_Chip-Seq_TH2_Human | 0.80566646 |
| 97 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.79023341 |
| 98 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.76571354 |
| 99 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.76451856 |
| 100 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.76147991 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0010094_abnormal_chromosome_stability | 3.12113113 |
| 2 | MP0002102_abnormal_ear_morphology | 3.07824212 |
| 3 | MP0008058_abnormal_DNA_repair | 3.03344598 |
| 4 | MP0004957_abnormal_blastocyst_morpholog | 2.93030835 |
| 5 | MP0003693_abnormal_embryo_hatching | 2.87208279 |
| 6 | MP0006292_abnormal_olfactory_placode | 2.63585923 |
| 7 | MP0005084_abnormal_gallbladder_morpholo | 2.56557852 |
| 8 | MP0001835_abnormal_antigen_presentation | 2.56153945 |
| 9 | MP0008877_abnormal_DNA_methylation | 2.53821030 |
| 10 | MP0008057_abnormal_DNA_replication | 2.51058799 |
| 11 | MP0003718_maternal_effect | 2.49872655 |
| 12 | MP0008872_abnormal_physiological_respon | 2.42929905 |
| 13 | MP0003806_abnormal_nucleotide_metabolis | 2.39582367 |
| 14 | MP0004147_increased_porphyrin_level | 2.34172898 |
| 15 | MP0008875_abnormal_xenobiotic_pharmacok | 2.08455206 |
| 16 | MP0003786_premature_aging | 2.07881295 |
| 17 | MP0006072_abnormal_retinal_apoptosis | 2.02570267 |
| 18 | MP0005671_abnormal_response_to | 1.94823770 |
| 19 | MP0003077_abnormal_cell_cycle | 1.86375871 |
| 20 | MP0002736_abnormal_nociception_after | 1.85712130 |
| 21 | MP0003111_abnormal_nucleus_morphology | 1.74979968 |
| 22 | MP0006036_abnormal_mitochondrial_physio | 1.74094972 |
| 23 | MP0001873_stomach_inflammation | 1.73020408 |
| 24 | MP0002938_white_spotting | 1.72611682 |
| 25 | MP0006035_abnormal_mitochondrial_morpho | 1.64395414 |
| 26 | MP0001293_anophthalmia | 1.62986369 |
| 27 | MP0003567_abnormal_fetal_cardiomyocyte | 1.61545942 |
| 28 | MP0008995_early_reproductive_senescence | 1.57696387 |
| 29 | MP0003186_abnormal_redox_activity | 1.57523332 |
| 30 | MP0009333_abnormal_splenocyte_physiolog | 1.53882930 |
| 31 | MP0002138_abnormal_hepatobiliary_system | 1.53832398 |
| 32 | MP0000372_irregular_coat_pigmentation | 1.50269096 |
| 33 | MP0000685_abnormal_immune_system | 1.49749009 |
| 34 | MP0001968_abnormal_touch/_nociception | 1.45931835 |
| 35 | MP0009697_abnormal_copulation | 1.45667978 |
| 36 | MP0002006_tumorigenesis | 1.45610039 |
| 37 | MP0009379_abnormal_foot_pigmentation | 1.41422144 |
| 38 | MP0003195_calcinosis | 1.38127648 |
| 39 | MP0002277_abnormal_respiratory_mucosa | 1.37509631 |
| 40 | MP0005646_abnormal_pituitary_gland | 1.35930073 |
| 41 | MP0005551_abnormal_eye_electrophysiolog | 1.32471354 |
| 42 | MP0001764_abnormal_homeostasis | 1.28327779 |
| 43 | MP0003890_abnormal_embryonic-extraembry | 1.27469045 |
| 44 | MP0002160_abnormal_reproductive_system | 1.19016529 |
| 45 | MP0004145_abnormal_muscle_electrophysio | 1.16930791 |
| 46 | MP0003787_abnormal_imprinting | 1.14613098 |
| 47 | MP0002148_abnormal_hypersensitivity_rea | 1.13779814 |
| 48 | MP0008932_abnormal_embryonic_tissue | 1.11243696 |
| 49 | MP0008007_abnormal_cellular_replicative | 1.10546536 |
| 50 | MP0001501_abnormal_sleep_pattern | 1.09680584 |
| 51 | MP0000647_abnormal_sebaceous_gland | 1.07852199 |
| 52 | MP0001790_abnormal_immune_system | 1.07523037 |
| 53 | MP0005387_immune_system_phenotype | 1.07523037 |
| 54 | MP0002234_abnormal_pharynx_morphology | 1.07448647 |
| 55 | MP0005253_abnormal_eye_physiology | 1.07403210 |
| 56 | MP0001529_abnormal_vocalization | 1.03652423 |
| 57 | MP0004782_abnormal_surfactant_physiolog | 1.03620850 |
| 58 | MP0004885_abnormal_endolymph | 1.01997462 |
| 59 | MP0010386_abnormal_urinary_bladder | 1.01683399 |
| 60 | MP0002166_altered_tumor_susceptibility | 1.01516723 |
| 61 | MP0003646_muscle_fatigue | 1.01369331 |
| 62 | MP0002837_dystrophic_cardiac_calcinosis | 0.99748412 |
| 63 | MP0005389_reproductive_system_phenotype | 0.99674349 |
| 64 | MP0009785_altered_susceptibility_to | 0.99108341 |
| 65 | MP0004133_heterotaxia | 0.98957084 |
| 66 | MP0005636_abnormal_mineral_homeostasis | 0.98789049 |
| 67 | MP0001485_abnormal_pinna_reflex | 0.97547472 |
| 68 | MP0005075_abnormal_melanosome_morpholog | 0.95327830 |
| 69 | MP0001984_abnormal_olfaction | 0.95123652 |
| 70 | MP0002210_abnormal_sex_determination | 0.95098277 |
| 71 | MP0001800_abnormal_humoral_immune | 0.94062701 |
| 72 | MP0005085_abnormal_gallbladder_physiolo | 0.93682532 |
| 73 | MP0005645_abnormal_hypothalamus_physiol | 0.93309812 |
| 74 | MP0002163_abnormal_gland_morphology | 0.92457729 |
| 75 | MP0008789_abnormal_olfactory_epithelium | 0.86543262 |
| 76 | MP0009764_decreased_sensitivity_to | 0.85475062 |
| 77 | MP0001929_abnormal_gametogenesis | 0.85000008 |
| 78 | MP0001119_abnormal_female_reproductive | 0.82748417 |
| 79 | MP0001853_heart_inflammation | 0.81584252 |
| 80 | MP0001881_abnormal_mammary_gland | 0.80458360 |
| 81 | MP0005395_other_phenotype | 0.80241334 |
| 82 | MP0001919_abnormal_reproductive_system | 0.79784252 |
| 83 | MP0000653_abnormal_sex_gland | 0.78157863 |
| 84 | MP0005332_abnormal_amino_acid | 0.74386107 |
| 85 | MP0000689_abnormal_spleen_morphology | 0.74031270 |
| 86 | MP0003011_delayed_dark_adaptation | 0.73783639 |
| 87 | MP0003119_abnormal_digestive_system | 0.73388515 |
| 88 | MP0001986_abnormal_taste_sensitivity | 0.73221996 |
| 89 | MP0006276_abnormal_autonomic_nervous | 0.72315526 |
| 90 | MP0005408_hypopigmentation | 0.71262955 |
| 91 | MP0005379_endocrine/exocrine_gland_phen | 0.70851642 |
| 92 | MP0005377_hearing/vestibular/ear_phenot | 0.70379773 |
| 93 | MP0003878_abnormal_ear_physiology | 0.70379773 |
| 94 | MP0001145_abnormal_male_reproductive | 0.69861861 |
| 95 | MP0001188_hyperpigmentation | 0.69490133 |
| 96 | MP0002019_abnormal_tumor_incidence | 0.69453979 |
| 97 | MP0005410_abnormal_fertilization | 0.69361733 |
| 98 | MP0008873_increased_physiological_sensi | 0.69161564 |
| 99 | MP0004142_abnormal_muscle_tone | 0.68584052 |
| 100 | MP0003936_abnormal_reproductive_system | 0.68529490 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.72408024 |
| 2 | Acute encephalopathy (HP:0006846) | 4.25263726 |
| 3 | Increased CSF lactate (HP:0002490) | 4.16418344 |
| 4 | Mitochondrial inheritance (HP:0001427) | 4.11674710 |
| 5 | Increased hepatocellular lipid droplets (HP:0006565) | 4.11619035 |
| 6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.06661884 |
| 7 | Progressive macrocephaly (HP:0004481) | 3.91052505 |
| 8 | Lipid accumulation in hepatocytes (HP:0006561) | 3.83233408 |
| 9 | Colon cancer (HP:0003003) | 3.34269502 |
| 10 | Stomatitis (HP:0010280) | 3.25824897 |
| 11 | Hepatocellular necrosis (HP:0001404) | 3.17050705 |
| 12 | Cerebral edema (HP:0002181) | 3.10974932 |
| 13 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.08117175 |
| 14 | Increased serum lactate (HP:0002151) | 3.06941263 |
| 15 | Abnormality of the labia minora (HP:0012880) | 2.98812249 |
| 16 | Methylmalonic acidemia (HP:0002912) | 2.94337555 |
| 17 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.89508083 |
| 18 | Renal Fanconi syndrome (HP:0001994) | 2.89422641 |
| 19 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.88926307 |
| 20 | Abnormality of alanine metabolism (HP:0010916) | 2.88926307 |
| 21 | Hyperalaninemia (HP:0003348) | 2.88926307 |
| 22 | Hepatic necrosis (HP:0002605) | 2.83734867 |
| 23 | Exertional dyspnea (HP:0002875) | 2.79885708 |
| 24 | Increased serum pyruvate (HP:0003542) | 2.79100843 |
| 25 | Abnormality of methionine metabolism (HP:0010901) | 2.74569516 |
| 26 | Abnormality of the pons (HP:0007361) | 2.70992429 |
| 27 | Abnormality of serum amino acid levels (HP:0003112) | 2.70351749 |
| 28 | Pancreatic cysts (HP:0001737) | 2.62360272 |
| 29 | Optic disc pallor (HP:0000543) | 2.60746181 |
| 30 | Aplastic anemia (HP:0001915) | 2.60662214 |
| 31 | Congenital, generalized hypertrichosis (HP:0004540) | 2.58119068 |
| 32 | IgG deficiency (HP:0004315) | 2.56106303 |
| 33 | Supernumerary spleens (HP:0009799) | 2.52055780 |
| 34 | Lactic acidosis (HP:0003128) | 2.50649678 |
| 35 | Constricted visual fields (HP:0001133) | 2.50499135 |
| 36 | Hyperglycinemia (HP:0002154) | 2.50194078 |
| 37 | Abnormal number of erythroid precursors (HP:0012131) | 2.43633374 |
| 38 | Multiple enchondromatosis (HP:0005701) | 2.41191473 |
| 39 | Increased intramyocellular lipid droplets (HP:0012240) | 2.40464975 |
| 40 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.38581022 |
| 41 | Exercise intolerance (HP:0003546) | 2.38288569 |
| 42 | Abnormality of glycolysis (HP:0004366) | 2.36821923 |
| 43 | Lethargy (HP:0001254) | 2.36299603 |
| 44 | Volvulus (HP:0002580) | 2.34567316 |
| 45 | Methylmalonic aciduria (HP:0012120) | 2.33357557 |
| 46 | Leukodystrophy (HP:0002415) | 2.32842172 |
| 47 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.32752873 |
| 48 | Pendular nystagmus (HP:0012043) | 2.32619549 |
| 49 | Abnormality of the ileum (HP:0001549) | 2.30127555 |
| 50 | 3-Methylglutaconic aciduria (HP:0003535) | 2.27098688 |
| 51 | Meckel diverticulum (HP:0002245) | 2.23562320 |
| 52 | Hypoplasia of the pons (HP:0012110) | 2.22834089 |
| 53 | Respiratory failure (HP:0002878) | 2.21640121 |
| 54 | Respiratory difficulties (HP:0002880) | 2.16446093 |
| 55 | Cerebral hypomyelination (HP:0006808) | 2.16239366 |
| 56 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.15472809 |
| 57 | True hermaphroditism (HP:0010459) | 2.15277655 |
| 58 | Duplicated collecting system (HP:0000081) | 2.14807868 |
| 59 | Pancreatic fibrosis (HP:0100732) | 2.13898611 |
| 60 | Macrocytic anemia (HP:0001972) | 2.08653204 |
| 61 | Pancytopenia (HP:0001876) | 2.07174840 |
| 62 | Premature ovarian failure (HP:0008209) | 2.04751228 |
| 63 | Abnormality of midbrain morphology (HP:0002418) | 2.02083053 |
| 64 | Molar tooth sign on MRI (HP:0002419) | 2.02083053 |
| 65 | Large for gestational age (HP:0001520) | 2.01725808 |
| 66 | Abolished electroretinogram (ERG) (HP:0000550) | 2.01591651 |
| 67 | Carpal bone hypoplasia (HP:0001498) | 1.99103872 |
| 68 | Reticulocytopenia (HP:0001896) | 1.98886772 |
| 69 | Oral leukoplakia (HP:0002745) | 1.98306363 |
| 70 | Glycosuria (HP:0003076) | 1.98040788 |
| 71 | Abnormality of urine glucose concentration (HP:0011016) | 1.98040788 |
| 72 | Attenuation of retinal blood vessels (HP:0007843) | 1.97341983 |
| 73 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.96853063 |
| 74 | Abnormality of glycine metabolism (HP:0010895) | 1.96853063 |
| 75 | Type 2 muscle fiber atrophy (HP:0003554) | 1.96788330 |
| 76 | Abnormality of the renal collecting system (HP:0004742) | 1.96729047 |
| 77 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.96160647 |
| 78 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.96160647 |
| 79 | Increased muscle lipid content (HP:0009058) | 1.94319374 |
| 80 | Nephronophthisis (HP:0000090) | 1.94229676 |
| 81 | Sensory axonal neuropathy (HP:0003390) | 1.89514851 |
| 82 | CNS demyelination (HP:0007305) | 1.89076792 |
| 83 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.89070002 |
| 84 | Abnormal lung lobation (HP:0002101) | 1.88620256 |
| 85 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 1.87315180 |
| 86 | Megaloblastic anemia (HP:0001889) | 1.84809781 |
| 87 | Hyperglycinuria (HP:0003108) | 1.84431739 |
| 88 | Abnormality of vitamin B metabolism (HP:0004340) | 1.83944876 |
| 89 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.82913797 |
| 90 | Increased IgM level (HP:0003496) | 1.82399178 |
| 91 | Hyperphosphaturia (HP:0003109) | 1.80434420 |
| 92 | Bile duct proliferation (HP:0001408) | 1.78533781 |
| 93 | Abnormal biliary tract physiology (HP:0012439) | 1.78533781 |
| 94 | Abnormality of renal resorption (HP:0011038) | 1.77180074 |
| 95 | Abnormality of the preputium (HP:0100587) | 1.76521347 |
| 96 | Homocystinuria (HP:0002156) | 1.76200825 |
| 97 | Abnormality of homocysteine metabolism (HP:0010919) | 1.76200825 |
| 98 | Type I transferrin isoform profile (HP:0003642) | 1.73540445 |
| 99 | Amniotic constriction ring (HP:0009775) | 1.73276727 |
| 100 | Abnormality of placental membranes (HP:0011409) | 1.73276727 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TSSK6 | 4.10496966 |
| 2 | VRK2 | 3.87898881 |
| 3 | EIF2AK3 | 3.78974748 |
| 4 | BUB1 | 3.51929156 |
| 5 | MST4 | 3.25031399 |
| 6 | NEK1 | 2.89210689 |
| 7 | EIF2AK1 | 2.71747416 |
| 8 | NUAK1 | 2.71027672 |
| 9 | ZAK | 2.55557558 |
| 10 | PLK3 | 2.41671101 |
| 11 | SRPK1 | 2.33873905 |
| 12 | PBK | 2.28471257 |
| 13 | VRK1 | 2.13455233 |
| 14 | MKNK1 | 2.02268251 |
| 15 | NME1 | 1.98841745 |
| 16 | MKNK2 | 1.87068687 |
| 17 | ADRBK2 | 1.85825319 |
| 18 | TRIM28 | 1.80709093 |
| 19 | STK16 | 1.80187745 |
| 20 | TLK1 | 1.79300725 |
| 21 | TAF1 | 1.72891253 |
| 22 | CDC7 | 1.71403413 |
| 23 | TXK | 1.54503349 |
| 24 | EIF2AK2 | 1.49194238 |
| 25 | GRK1 | 1.43921306 |
| 26 | MAP3K12 | 1.41086516 |
| 27 | WNK3 | 1.37563296 |
| 28 | PLK4 | 1.36997520 |
| 29 | TTK | 1.36196532 |
| 30 | MAP4K2 | 1.32718559 |
| 31 | TNIK | 1.32119364 |
| 32 | PASK | 1.31368930 |
| 33 | WNK4 | 1.30792093 |
| 34 | OXSR1 | 1.25590833 |
| 35 | ALK | 1.16250813 |
| 36 | STK39 | 1.11763263 |
| 37 | FRK | 1.07204011 |
| 38 | TAOK3 | 1.05722713 |
| 39 | CDK19 | 1.02418041 |
| 40 | PLK1 | 1.02353817 |
| 41 | BMPR1B | 0.99772551 |
| 42 | DAPK1 | 0.99692423 |
| 43 | ERBB3 | 0.96653840 |
| 44 | DYRK2 | 0.93935451 |
| 45 | TIE1 | 0.83989242 |
| 46 | PLK2 | 0.82664466 |
| 47 | ATR | 0.76311414 |
| 48 | AURKB | 0.75056611 |
| 49 | TEC | 0.73222448 |
| 50 | PDK2 | 0.69714175 |
| 51 | ACVR1B | 0.69347068 |
| 52 | BRSK2 | 0.64455724 |
| 53 | CSNK1G1 | 0.63525263 |
| 54 | PAK4 | 0.61979472 |
| 55 | BCR | 0.61898567 |
| 56 | MYLK | 0.60704283 |
| 57 | SCYL2 | 0.59976129 |
| 58 | STK38L | 0.59704997 |
| 59 | CSNK1G3 | 0.59080834 |
| 60 | FGFR1 | 0.57858838 |
| 61 | INSRR | 0.55219231 |
| 62 | CSNK2A2 | 0.54829952 |
| 63 | IKBKB | 0.53316064 |
| 64 | NME2 | 0.52055774 |
| 65 | CSNK2A1 | 0.50639361 |
| 66 | BCKDK | 0.49933420 |
| 67 | TGFBR1 | 0.49772945 |
| 68 | CSNK1G2 | 0.48081917 |
| 69 | BMPR2 | 0.46722393 |
| 70 | WEE1 | 0.46614937 |
| 71 | FLT3 | 0.45270870 |
| 72 | ADRBK1 | 0.43852447 |
| 73 | CHEK2 | 0.43804224 |
| 74 | PRKCE | 0.43520223 |
| 75 | STK3 | 0.43371168 |
| 76 | RPS6KA5 | 0.42182041 |
| 77 | CSNK1A1L | 0.41154569 |
| 78 | CSNK1E | 0.40259231 |
| 79 | RPS6KA4 | 0.39080982 |
| 80 | STK4 | 0.38139956 |
| 81 | KDR | 0.37753587 |
| 82 | NEK2 | 0.37703398 |
| 83 | DAPK3 | 0.36405510 |
| 84 | ILK | 0.35013970 |
| 85 | ATM | 0.34193363 |
| 86 | PRKCG | 0.32190387 |
| 87 | BRSK1 | 0.32114236 |
| 88 | DAPK2 | 0.30942796 |
| 89 | CLK1 | 0.30860181 |
| 90 | CSNK1A1 | 0.30652586 |
| 91 | JAK3 | 0.30361232 |
| 92 | MAPKAPK5 | 0.29098375 |
| 93 | MAP3K4 | 0.28163627 |
| 94 | PHKG1 | 0.27702721 |
| 95 | PHKG2 | 0.27702721 |
| 96 | CDK7 | 0.27630595 |
| 97 | PIK3CG | 0.27094698 |
| 98 | CHEK1 | 0.27024751 |
| 99 | PRKCQ | 0.25904901 |
| 100 | BRD4 | 0.25238971 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 5.09667713 |
| 2 | Protein export_Homo sapiens_hsa03060 | 3.26646165 |
| 3 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.04512684 |
| 4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.02096549 |
| 5 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.84473454 |
| 6 | Ribosome_Homo sapiens_hsa03010 | 2.74709492 |
| 7 | Parkinsons disease_Homo sapiens_hsa05012 | 2.55897565 |
| 8 | RNA polymerase_Homo sapiens_hsa03020 | 2.51291591 |
| 9 | Mismatch repair_Homo sapiens_hsa03430 | 2.47999681 |
| 10 | Asthma_Homo sapiens_hsa05310 | 2.44028781 |
| 11 | DNA replication_Homo sapiens_hsa03030 | 2.26178959 |
| 12 | Homologous recombination_Homo sapiens_hsa03440 | 2.20778732 |
| 13 | RNA transport_Homo sapiens_hsa03013 | 2.04330053 |
| 14 | Basal transcription factors_Homo sapiens_hsa03022 | 1.93527109 |
| 15 | RNA degradation_Homo sapiens_hsa03018 | 1.90206710 |
| 16 | Spliceosome_Homo sapiens_hsa03040 | 1.88288337 |
| 17 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.81622034 |
| 18 | Allograft rejection_Homo sapiens_hsa05330 | 1.78150890 |
| 19 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.74187852 |
| 20 | Base excision repair_Homo sapiens_hsa03410 | 1.72262189 |
| 21 | Huntingtons disease_Homo sapiens_hsa05016 | 1.71298322 |
| 22 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.70255902 |
| 23 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.59324066 |
| 24 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.58722986 |
| 25 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.54469550 |
| 26 | Alzheimers disease_Homo sapiens_hsa05010 | 1.52126587 |
| 27 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.51483409 |
| 28 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.49114711 |
| 29 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.37043938 |
| 30 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.31796468 |
| 31 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.29904293 |
| 32 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.28422224 |
| 33 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.25608362 |
| 34 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.23626016 |
| 35 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.22926277 |
| 36 | Purine metabolism_Homo sapiens_hsa00230 | 1.13369379 |
| 37 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.10415582 |
| 38 | Phototransduction_Homo sapiens_hsa04744 | 1.04472617 |
| 39 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.03950352 |
| 40 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.03474666 |
| 41 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.01548292 |
| 42 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.00693449 |
| 43 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.99928070 |
| 44 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.97128402 |
| 45 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.94138646 |
| 46 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.93970790 |
| 47 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.91013103 |
| 48 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.88509486 |
| 49 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.82546994 |
| 50 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.77862894 |
| 51 | Cell cycle_Homo sapiens_hsa04110 | 0.74767389 |
| 52 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.73664421 |
| 53 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.73615376 |
| 54 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.73109595 |
| 55 | Peroxisome_Homo sapiens_hsa04146 | 0.72925611 |
| 56 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.67411983 |
| 57 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.66790616 |
| 58 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.66390057 |
| 59 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.66030930 |
| 60 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.65366771 |
| 61 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.64756437 |
| 62 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.64702890 |
| 63 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.63769104 |
| 64 | Metabolic pathways_Homo sapiens_hsa01100 | 0.61756206 |
| 65 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.61042222 |
| 66 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.59615526 |
| 67 | Retinol metabolism_Homo sapiens_hsa00830 | 0.55260751 |
| 68 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.54327852 |
| 69 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.53338821 |
| 70 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.52983373 |
| 71 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.50982400 |
| 72 | Sulfur relay system_Homo sapiens_hsa04122 | 0.48790598 |
| 73 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.48388915 |
| 74 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.48105720 |
| 75 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.47426312 |
| 76 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.46467442 |
| 77 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.46365702 |
| 78 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.46122021 |
| 79 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.45662545 |
| 80 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.45575910 |
| 81 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.45397002 |
| 82 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.44953633 |
| 83 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.43286009 |
| 84 | Carbon metabolism_Homo sapiens_hsa01200 | 0.42308974 |
| 85 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.41792267 |
| 86 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.41375075 |
| 87 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.40974876 |
| 88 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.39974691 |
| 89 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.36156590 |
| 90 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.35886536 |
| 91 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.34195268 |
| 92 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.33864333 |
| 93 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.33799972 |
| 94 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.31638852 |
| 95 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.29389804 |
| 96 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.29054253 |
| 97 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.28751349 |
| 98 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.27300186 |
| 99 | Legionellosis_Homo sapiens_hsa05134 | 0.26583332 |
| 100 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.26074922 |

