

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | proteasome assembly (GO:0043248) | 5.57357452 |
| 2 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.32777461 |
| 3 | DNA deamination (GO:0045006) | 4.86413749 |
| 4 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.70388436 |
| 5 | ATP synthesis coupled proton transport (GO:0015986) | 4.49756532 |
| 6 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.49756532 |
| 7 | protein K6-linked ubiquitination (GO:0085020) | 4.29514960 |
| 8 | chaperone-mediated protein transport (GO:0072321) | 4.18028207 |
| 9 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.07103407 |
| 10 | protein neddylation (GO:0045116) | 3.99856253 |
| 11 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.98893636 |
| 12 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.97533385 |
| 13 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.83773498 |
| 14 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.81137095 |
| 15 | rRNA modification (GO:0000154) | 3.78394091 |
| 16 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.77418277 |
| 17 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.76009766 |
| 18 | protein complex biogenesis (GO:0070271) | 3.73966490 |
| 19 | CENP-A containing nucleosome assembly (GO:0034080) | 3.72958892 |
| 20 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.72951775 |
| 21 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.72181235 |
| 22 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.72181235 |
| 23 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.72181235 |
| 24 | ribosome assembly (GO:0042255) | 3.70960671 |
| 25 | pseudouridine synthesis (GO:0001522) | 3.69927501 |
| 26 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.68697234 |
| 27 | chromatin remodeling at centromere (GO:0031055) | 3.67957806 |
| 28 | negative regulation of ligase activity (GO:0051352) | 3.67718482 |
| 29 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.67718482 |
| 30 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.65565747 |
| 31 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.65565747 |
| 32 | NADH dehydrogenase complex assembly (GO:0010257) | 3.65565747 |
| 33 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.63884760 |
| 34 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.63884760 |
| 35 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.62636285 |
| 36 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.62163991 |
| 37 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.56424242 |
| 38 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.53381088 |
| 39 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.53381088 |
| 40 | respiratory chain complex IV assembly (GO:0008535) | 3.48519195 |
| 41 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.48021306 |
| 42 | DNA double-strand break processing (GO:0000729) | 3.47968375 |
| 43 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.39339800 |
| 44 | cullin deneddylation (GO:0010388) | 3.39297283 |
| 45 | DNA replication checkpoint (GO:0000076) | 3.38934395 |
| 46 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.37772973 |
| 47 | isotype switching (GO:0045190) | 3.37772973 |
| 48 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.37772973 |
| 49 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.37713684 |
| 50 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.37713684 |
| 51 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.35427488 |
| 52 | positive regulation of ligase activity (GO:0051351) | 3.23805510 |
| 53 | protein deneddylation (GO:0000338) | 3.23751174 |
| 54 | histone exchange (GO:0043486) | 3.21234463 |
| 55 | termination of RNA polymerase III transcription (GO:0006386) | 3.19906489 |
| 56 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.19906489 |
| 57 | respiratory electron transport chain (GO:0022904) | 3.19251842 |
| 58 | rRNA methylation (GO:0031167) | 3.18827447 |
| 59 | electron transport chain (GO:0022900) | 3.16638870 |
| 60 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.11522961 |
| 61 | maturation of 5.8S rRNA (GO:0000460) | 3.10562073 |
| 62 | cytochrome complex assembly (GO:0017004) | 3.10085518 |
| 63 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.06389217 |
| 64 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.06286140 |
| 65 | protein-cofactor linkage (GO:0018065) | 2.97564204 |
| 66 | synapsis (GO:0007129) | 2.95277573 |
| 67 | positive regulation of protein homodimerization activity (GO:0090073) | 2.92541226 |
| 68 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.91625968 |
| 69 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.91625968 |
| 70 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.91518532 |
| 71 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.89948361 |
| 72 | rRNA processing (GO:0006364) | 2.88923787 |
| 73 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.88816452 |
| 74 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.87506681 |
| 75 | kinetochore assembly (GO:0051382) | 2.85555620 |
| 76 | rRNA metabolic process (GO:0016072) | 2.84197549 |
| 77 | purine nucleobase biosynthetic process (GO:0009113) | 2.81926271 |
| 78 | replication fork processing (GO:0031297) | 2.81163801 |
| 79 | regulation of ligase activity (GO:0051340) | 2.81110425 |
| 80 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.80767728 |
| 81 | regulation of immunoglobulin secretion (GO:0051023) | 2.79385701 |
| 82 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.79236306 |
| 83 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.79236306 |
| 84 | IMP biosynthetic process (GO:0006188) | 2.77858223 |
| 85 | tRNA processing (GO:0008033) | 2.75235780 |
| 86 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.74285626 |
| 87 | positive regulation of cell cycle arrest (GO:0071158) | 2.72203711 |
| 88 | ribosomal large subunit biogenesis (GO:0042273) | 2.71918978 |
| 89 | aldehyde catabolic process (GO:0046185) | 2.71853349 |
| 90 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.71714775 |
| 91 | somatic diversification of immunoglobulins (GO:0016445) | 2.71209083 |
| 92 | tRNA metabolic process (GO:0006399) | 2.70927420 |
| 93 | regulation of cellular amine metabolic process (GO:0033238) | 2.70622790 |
| 94 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.69040203 |
| 95 | ATP biosynthetic process (GO:0006754) | 2.68845194 |
| 96 | double-strand break repair via homologous recombination (GO:0000724) | 2.67529480 |
| 97 | histone mRNA metabolic process (GO:0008334) | 2.67488194 |
| 98 | recombinational repair (GO:0000725) | 2.67171862 |
| 99 | nucleobase biosynthetic process (GO:0046112) | 2.66824799 |
| 100 | cytidine catabolic process (GO:0006216) | 2.66269217 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.82889510 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.27058766 |
| 3 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.05483259 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.82832779 |
| 5 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.22625816 |
| 6 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.05603486 |
| 7 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.97017934 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.82991742 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.76939518 |
| 10 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.67043254 |
| 11 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.65006879 |
| 12 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.61270170 |
| 13 | VDR_22108803_ChIP-Seq_LS180_Human | 2.54745126 |
| 14 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.52808970 |
| 15 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.49131036 |
| 16 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.44181737 |
| 17 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.32133654 |
| 18 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.31387200 |
| 19 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.16856697 |
| 20 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.13521579 |
| 21 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.08630278 |
| 22 | EWS_26573619_Chip-Seq_HEK293_Human | 2.01091639 |
| 23 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.95679313 |
| 24 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.93343802 |
| 25 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.90367603 |
| 26 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.89545901 |
| 27 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.85795369 |
| 28 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.74690191 |
| 29 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.72160406 |
| 30 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.70863361 |
| 31 | FUS_26573619_Chip-Seq_HEK293_Human | 1.67225301 |
| 32 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.65176195 |
| 33 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.63468592 |
| 34 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.61052911 |
| 35 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.55413098 |
| 36 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.55000130 |
| 37 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.52736473 |
| 38 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.50331650 |
| 39 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.49881562 |
| 40 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.48178958 |
| 41 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.45978554 |
| 42 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.42616784 |
| 43 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.42198016 |
| 44 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.39791985 |
| 45 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.38297370 |
| 46 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.33100628 |
| 47 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.31927876 |
| 48 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.31202111 |
| 49 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.29169866 |
| 50 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.28787211 |
| 51 | P300_19829295_ChIP-Seq_ESCs_Human | 1.25196946 |
| 52 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.24386661 |
| 53 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.24386661 |
| 54 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.20963797 |
| 55 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.20530403 |
| 56 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.20520838 |
| 57 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.20167099 |
| 58 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.20167099 |
| 59 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.20014189 |
| 60 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.20010318 |
| 61 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.16781383 |
| 62 | GATA3_26560356_Chip-Seq_TH2_Human | 1.16732319 |
| 63 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.15216522 |
| 64 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.14722896 |
| 65 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.13728962 |
| 66 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.13513317 |
| 67 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.12815281 |
| 68 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.11374764 |
| 69 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.10913169 |
| 70 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.09429019 |
| 71 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.09273808 |
| 72 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.07669115 |
| 73 | AR_20517297_ChIP-Seq_VCAP_Human | 1.07140105 |
| 74 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.04594149 |
| 75 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.02535036 |
| 76 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.00774988 |
| 77 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.00318745 |
| 78 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.00318745 |
| 79 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.99645348 |
| 80 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.98543885 |
| 81 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.97709760 |
| 82 | NCOR_22424771_ChIP-Seq_293T_Human | 0.96709400 |
| 83 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.95325872 |
| 84 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.94163678 |
| 85 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.93143249 |
| 86 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.92201344 |
| 87 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.92024685 |
| 88 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.91591787 |
| 89 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.91406880 |
| 90 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.90910645 |
| 91 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.90459931 |
| 92 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.89782839 |
| 93 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.89065359 |
| 94 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.89048163 |
| 95 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 0.88554462 |
| 96 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.88270979 |
| 97 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.87081458 |
| 98 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.86614311 |
| 99 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.86089926 |
| 100 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.85774529 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008877_abnormal_DNA_methylation | 3.87783658 |
| 2 | MP0003806_abnormal_nucleotide_metabolis | 3.32004033 |
| 3 | MP0003693_abnormal_embryo_hatching | 3.16871725 |
| 4 | MP0010094_abnormal_chromosome_stability | 3.11613322 |
| 5 | MP0001835_abnormal_antigen_presentation | 3.09082235 |
| 6 | MP0008058_abnormal_DNA_repair | 2.99561007 |
| 7 | MP0004147_increased_porphyrin_level | 2.72140259 |
| 8 | MP0003195_calcinosis | 2.69670468 |
| 9 | MP0004957_abnormal_blastocyst_morpholog | 2.55683665 |
| 10 | MP0004145_abnormal_muscle_electrophysio | 2.50055484 |
| 11 | MP0006072_abnormal_retinal_apoptosis | 2.42179260 |
| 12 | MP0003718_maternal_effect | 2.39073775 |
| 13 | MP0006036_abnormal_mitochondrial_physio | 2.34067979 |
| 14 | MP0002138_abnormal_hepatobiliary_system | 2.32176179 |
| 15 | MP0008872_abnormal_physiological_respon | 2.31821756 |
| 16 | MP0002102_abnormal_ear_morphology | 2.29424599 |
| 17 | MP0003786_premature_aging | 2.26755325 |
| 18 | MP0008057_abnormal_DNA_replication | 2.14192507 |
| 19 | MP0006035_abnormal_mitochondrial_morpho | 2.06685281 |
| 20 | MP0006292_abnormal_olfactory_placode | 2.06682893 |
| 21 | MP0005671_abnormal_response_to | 2.03271599 |
| 22 | MP0005084_abnormal_gallbladder_morpholo | 2.00951898 |
| 23 | MP0005646_abnormal_pituitary_gland | 1.92617400 |
| 24 | MP0009697_abnormal_copulation | 1.86267367 |
| 25 | MP0005645_abnormal_hypothalamus_physiol | 1.79101659 |
| 26 | MP0000372_irregular_coat_pigmentation | 1.72119992 |
| 27 | MP0003111_abnormal_nucleus_morphology | 1.66849353 |
| 28 | MP0004215_abnormal_myocardial_fiber | 1.62585651 |
| 29 | MP0003646_muscle_fatigue | 1.59947920 |
| 30 | MP0001968_abnormal_touch/_nociception | 1.59888348 |
| 31 | MP0008875_abnormal_xenobiotic_pharmacok | 1.57180484 |
| 32 | MP0001873_stomach_inflammation | 1.56245781 |
| 33 | MP0003077_abnormal_cell_cycle | 1.48656814 |
| 34 | MP0002736_abnormal_nociception_after | 1.46113985 |
| 35 | MP0005551_abnormal_eye_electrophysiolog | 1.45469911 |
| 36 | MP0008007_abnormal_cellular_replicative | 1.44793340 |
| 37 | MP0003186_abnormal_redox_activity | 1.41740979 |
| 38 | MP0002006_tumorigenesis | 1.37926716 |
| 39 | MP0005253_abnormal_eye_physiology | 1.36181574 |
| 40 | MP0002837_dystrophic_cardiac_calcinosis | 1.34343286 |
| 41 | MP0008775_abnormal_heart_ventricle | 1.24492077 |
| 42 | MP0008995_early_reproductive_senescence | 1.24353741 |
| 43 | MP0001986_abnormal_taste_sensitivity | 1.22671753 |
| 44 | MP0002166_altered_tumor_susceptibility | 1.21981575 |
| 45 | MP0009785_altered_susceptibility_to | 1.20261309 |
| 46 | MP0002148_abnormal_hypersensitivity_rea | 1.19876841 |
| 47 | MP0001764_abnormal_homeostasis | 1.16747439 |
| 48 | MP0000685_abnormal_immune_system | 1.16730676 |
| 49 | MP0002160_abnormal_reproductive_system | 1.16117983 |
| 50 | MP0001800_abnormal_humoral_immune | 1.14490799 |
| 51 | MP0009333_abnormal_splenocyte_physiolog | 1.14136348 |
| 52 | MP0005075_abnormal_melanosome_morpholog | 1.12115775 |
| 53 | MP0004782_abnormal_surfactant_physiolog | 1.09886173 |
| 54 | MP0005389_reproductive_system_phenotype | 1.09374723 |
| 55 | MP0001293_anophthalmia | 1.05880935 |
| 56 | MP0002938_white_spotting | 1.02266127 |
| 57 | MP0001853_heart_inflammation | 1.02178556 |
| 58 | MP0003950_abnormal_plasma_membrane | 0.99311421 |
| 59 | MP0002277_abnormal_respiratory_mucosa | 0.98764765 |
| 60 | MP0005377_hearing/vestibular/ear_phenot | 0.97652760 |
| 61 | MP0003878_abnormal_ear_physiology | 0.97652760 |
| 62 | MP0001929_abnormal_gametogenesis | 0.96969014 |
| 63 | MP0002751_abnormal_autonomic_nervous | 0.92630056 |
| 64 | MP0002210_abnormal_sex_determination | 0.92007216 |
| 65 | MP0002272_abnormal_nervous_system | 0.91701317 |
| 66 | MP0009764_decreased_sensitivity_to | 0.90326405 |
| 67 | MP0001119_abnormal_female_reproductive | 0.87044077 |
| 68 | MP0002876_abnormal_thyroid_physiology | 0.86036385 |
| 69 | MP0001485_abnormal_pinna_reflex | 0.85967306 |
| 70 | MP0006054_spinal_hemorrhage | 0.84325719 |
| 71 | MP0005000_abnormal_immune_tolerance | 0.84220261 |
| 72 | MP0005410_abnormal_fertilization | 0.83705472 |
| 73 | MP0000653_abnormal_sex_gland | 0.82329430 |
| 74 | MP0004885_abnormal_endolymph | 0.80470350 |
| 75 | MP0000358_abnormal_cell_content/ | 0.80025683 |
| 76 | MP0001905_abnormal_dopamine_level | 0.79643811 |
| 77 | MP0002234_abnormal_pharynx_morphology | 0.79056471 |
| 78 | MP0001919_abnormal_reproductive_system | 0.76390250 |
| 79 | MP0002452_abnormal_antigen_presenting | 0.76374035 |
| 80 | MP0004142_abnormal_muscle_tone | 0.75715936 |
| 81 | MP0005636_abnormal_mineral_homeostasis | 0.75582977 |
| 82 | MP0002019_abnormal_tumor_incidence | 0.75436119 |
| 83 | MP0005395_other_phenotype | 0.72885982 |
| 84 | MP0001790_abnormal_immune_system | 0.72751705 |
| 85 | MP0005387_immune_system_phenotype | 0.72751705 |
| 86 | MP0000689_abnormal_spleen_morphology | 0.72630221 |
| 87 | MP0002693_abnormal_pancreas_physiology | 0.72569225 |
| 88 | MP0008932_abnormal_embryonic_tissue | 0.72037511 |
| 89 | MP0005085_abnormal_gallbladder_physiolo | 0.70000256 |
| 90 | MP0002723_abnormal_immune_serum | 0.69936473 |
| 91 | MP0005266_abnormal_metabolism | 0.69843232 |
| 92 | MP0001145_abnormal_male_reproductive | 0.68570966 |
| 93 | MP0005332_abnormal_amino_acid | 0.67194823 |
| 94 | MP0009046_muscle_twitch | 0.66990467 |
| 95 | MP0001819_abnormal_immune_cell | 0.66967472 |
| 96 | MP0002420_abnormal_adaptive_immunity | 0.66962068 |
| 97 | MP0010307_abnormal_tumor_latency | 0.66082091 |
| 98 | MP0002398_abnormal_bone_marrow | 0.66028361 |
| 99 | MP0001984_abnormal_olfaction | 0.65119108 |
| 100 | MP0010386_abnormal_urinary_bladder | 0.64654575 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Increased CSF lactate (HP:0002490) | 4.00651846 |
| 2 | Increased hepatocellular lipid droplets (HP:0006565) | 3.96009557 |
| 3 | Mitochondrial inheritance (HP:0001427) | 3.93444710 |
| 4 | Lipid accumulation in hepatocytes (HP:0006561) | 3.92308665 |
| 5 | Acute necrotizing encephalopathy (HP:0006965) | 3.76722265 |
| 6 | Hepatocellular necrosis (HP:0001404) | 3.67359218 |
| 7 | Acute encephalopathy (HP:0006846) | 3.53438055 |
| 8 | Hepatic necrosis (HP:0002605) | 3.37712101 |
| 9 | 3-Methylglutaconic aciduria (HP:0003535) | 3.32255083 |
| 10 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.20589664 |
| 11 | Progressive macrocephaly (HP:0004481) | 3.15795045 |
| 12 | IgG deficiency (HP:0004315) | 3.10172253 |
| 13 | Increased serum lactate (HP:0002151) | 3.08455402 |
| 14 | Stomatitis (HP:0010280) | 3.03925653 |
| 15 | Pancreatic cysts (HP:0001737) | 2.90684599 |
| 16 | Cerebral edema (HP:0002181) | 2.87447896 |
| 17 | Exertional dyspnea (HP:0002875) | 2.86234410 |
| 18 | Abnormality of methionine metabolism (HP:0010901) | 2.85845549 |
| 19 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.80273267 |
| 20 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.75456688 |
| 21 | Renal Fanconi syndrome (HP:0001994) | 2.75371160 |
| 22 | Abnormality of the labia minora (HP:0012880) | 2.71447014 |
| 23 | Supernumerary spleens (HP:0009799) | 2.64374635 |
| 24 | Abnormality of B cell number (HP:0010975) | 2.56397308 |
| 25 | Methylmalonic acidemia (HP:0002912) | 2.55257670 |
| 26 | Lactic acidosis (HP:0003128) | 2.54402603 |
| 27 | Prostate neoplasm (HP:0100787) | 2.54044425 |
| 28 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.52262427 |
| 29 | Abnormality of alanine metabolism (HP:0010916) | 2.52262427 |
| 30 | Hyperalaninemia (HP:0003348) | 2.52262427 |
| 31 | Colon cancer (HP:0003003) | 2.52027546 |
| 32 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.48096650 |
| 33 | Increased intramyocellular lipid droplets (HP:0012240) | 2.43922078 |
| 34 | Abolished electroretinogram (ERG) (HP:0000550) | 2.41644637 |
| 35 | Meckel diverticulum (HP:0002245) | 2.41092251 |
| 36 | Abnormality of the ileum (HP:0001549) | 2.40890170 |
| 37 | B lymphocytopenia (HP:0010976) | 2.40261086 |
| 38 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.40022172 |
| 39 | Aplastic anemia (HP:0001915) | 2.34967420 |
| 40 | Congenital, generalized hypertrichosis (HP:0004540) | 2.34656945 |
| 41 | Pancreatic fibrosis (HP:0100732) | 2.34299391 |
| 42 | Increased serum pyruvate (HP:0003542) | 2.32144517 |
| 43 | Abnormality of the prostate (HP:0008775) | 2.31853735 |
| 44 | Abnormality of chromosome stability (HP:0003220) | 2.26904113 |
| 45 | Congenital stationary night blindness (HP:0007642) | 2.25231360 |
| 46 | Respiratory failure (HP:0002878) | 2.24112686 |
| 47 | Nephronophthisis (HP:0000090) | 2.22919789 |
| 48 | Optic disc pallor (HP:0000543) | 2.21443771 |
| 49 | Lethargy (HP:0001254) | 2.20684863 |
| 50 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.20056575 |
| 51 | Respiratory difficulties (HP:0002880) | 2.19941570 |
| 52 | Methylmalonic aciduria (HP:0012120) | 2.18772118 |
| 53 | Hyperglycinuria (HP:0003108) | 2.18098118 |
| 54 | Clubbing of toes (HP:0100760) | 2.16301035 |
| 55 | True hermaphroditism (HP:0010459) | 2.15951431 |
| 56 | Abnormality of the pons (HP:0007361) | 2.13998075 |
| 57 | Increased muscle lipid content (HP:0009058) | 2.12676456 |
| 58 | Facial diplegia (HP:0001349) | 2.11152068 |
| 59 | Microvesicular hepatic steatosis (HP:0001414) | 2.08487191 |
| 60 | Abnormality of serum amino acid levels (HP:0003112) | 2.08391161 |
| 61 | Abnormality of the renal cortex (HP:0011035) | 2.08027456 |
| 62 | Molar tooth sign on MRI (HP:0002419) | 2.06961395 |
| 63 | Abnormality of midbrain morphology (HP:0002418) | 2.06961395 |
| 64 | Exercise intolerance (HP:0003546) | 2.06586445 |
| 65 | Severe combined immunodeficiency (HP:0004430) | 2.06539156 |
| 66 | Chromsome breakage (HP:0040012) | 2.06130959 |
| 67 | Chronic sinusitis (HP:0011109) | 2.05811002 |
| 68 | Pendular nystagmus (HP:0012043) | 2.05746850 |
| 69 | Abnormality of urine glucose concentration (HP:0011016) | 2.05651417 |
| 70 | Glycosuria (HP:0003076) | 2.05651417 |
| 71 | Abnormality of the preputium (HP:0100587) | 2.04992073 |
| 72 | CNS demyelination (HP:0007305) | 2.04793555 |
| 73 | Hypoproteinemia (HP:0003075) | 2.03563091 |
| 74 | Pancytopenia (HP:0001876) | 2.00578743 |
| 75 | Renal cortical cysts (HP:0000803) | 1.98932314 |
| 76 | Adrenal hypoplasia (HP:0000835) | 1.98376664 |
| 77 | Increased IgM level (HP:0003496) | 1.97892196 |
| 78 | Duplicated collecting system (HP:0000081) | 1.96162339 |
| 79 | Large for gestational age (HP:0001520) | 1.95487530 |
| 80 | Type I transferrin isoform profile (HP:0003642) | 1.93790695 |
| 81 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.93122748 |
| 82 | Hypothermia (HP:0002045) | 1.92907270 |
| 83 | Abnormality of the renal collecting system (HP:0004742) | 1.92100570 |
| 84 | Abnormality of glycolysis (HP:0004366) | 1.90578334 |
| 85 | Small intestinal stenosis (HP:0012848) | 1.89879290 |
| 86 | Duodenal stenosis (HP:0100867) | 1.89879290 |
| 87 | Panhypogammaglobulinemia (HP:0003139) | 1.84908257 |
| 88 | Constricted visual fields (HP:0001133) | 1.84711163 |
| 89 | Leukodystrophy (HP:0002415) | 1.82742366 |
| 90 | Abnormality of the renal medulla (HP:0100957) | 1.80668084 |
| 91 | Azoospermia (HP:0000027) | 1.80660487 |
| 92 | Abnormal spermatogenesis (HP:0008669) | 1.78181419 |
| 93 | Parakeratosis (HP:0001036) | 1.77978287 |
| 94 | Decreased central vision (HP:0007663) | 1.77359448 |
| 95 | Hyperglycinemia (HP:0002154) | 1.77168296 |
| 96 | Hypoplasia of the pons (HP:0012110) | 1.77087057 |
| 97 | Attenuation of retinal blood vessels (HP:0007843) | 1.76985135 |
| 98 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.76757999 |
| 99 | Abnormality of glycine metabolism (HP:0010895) | 1.76757999 |
| 100 | Sloping forehead (HP:0000340) | 1.76597876 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EIF2AK3 | 3.51424397 |
| 2 | BUB1 | 3.16062992 |
| 3 | VRK2 | 2.98922276 |
| 4 | ZAK | 2.98066254 |
| 5 | TSSK6 | 2.89545217 |
| 6 | BMPR1B | 2.74591919 |
| 7 | MST4 | 2.65580250 |
| 8 | MKNK2 | 2.52601845 |
| 9 | NUAK1 | 2.37997988 |
| 10 | TLK1 | 2.35546078 |
| 11 | EIF2AK1 | 2.31292184 |
| 12 | MKNK1 | 2.26257931 |
| 13 | PBK | 2.22516035 |
| 14 | TAOK3 | 2.17245784 |
| 15 | PLK3 | 2.14336986 |
| 16 | NEK1 | 2.00829281 |
| 17 | GRK1 | 2.00019105 |
| 18 | TRIM28 | 1.96881854 |
| 19 | SRPK1 | 1.85416678 |
| 20 | ADRBK2 | 1.80782441 |
| 21 | VRK1 | 1.77813631 |
| 22 | TXK | 1.72398636 |
| 23 | WNK3 | 1.72055744 |
| 24 | MAP3K12 | 1.66559692 |
| 25 | TNIK | 1.54989385 |
| 26 | EIF2AK2 | 1.54730062 |
| 27 | FRK | 1.53141196 |
| 28 | ERBB3 | 1.41076758 |
| 29 | TTK | 1.37710459 |
| 30 | TAF1 | 1.29393433 |
| 31 | TEC | 1.24531872 |
| 32 | BCKDK | 1.22017535 |
| 33 | CDC7 | 1.21369413 |
| 34 | TGFBR1 | 1.20585828 |
| 35 | PLK4 | 1.17511291 |
| 36 | PASK | 1.15271032 |
| 37 | STK16 | 1.14778458 |
| 38 | OXSR1 | 1.14342529 |
| 39 | STK39 | 1.14157406 |
| 40 | NME1 | 1.10101010 |
| 41 | ACVR1B | 1.06927413 |
| 42 | BMPR2 | 1.05321003 |
| 43 | MAP4K2 | 1.03201629 |
| 44 | PLK1 | 1.01582399 |
| 45 | WEE1 | 1.01350011 |
| 46 | ALK | 0.94335709 |
| 47 | CDK8 | 0.92715885 |
| 48 | WNK4 | 0.89045953 |
| 49 | PLK2 | 0.87652421 |
| 50 | MAPKAPK5 | 0.87610082 |
| 51 | SCYL2 | 0.87342509 |
| 52 | DAPK1 | 0.84533169 |
| 53 | MAP3K4 | 0.79631787 |
| 54 | AURKB | 0.78631458 |
| 55 | ATR | 0.77667135 |
| 56 | CCNB1 | 0.74676653 |
| 57 | STK38L | 0.71453000 |
| 58 | NEK2 | 0.69719712 |
| 59 | TIE1 | 0.67463031 |
| 60 | PHKG1 | 0.65505473 |
| 61 | PHKG2 | 0.65505473 |
| 62 | IKBKB | 0.64847487 |
| 63 | ITK | 0.64141042 |
| 64 | BRSK2 | 0.61791064 |
| 65 | PDK2 | 0.60904017 |
| 66 | FLT3 | 0.58489684 |
| 67 | CHEK2 | 0.57896012 |
| 68 | MAP3K14 | 0.56582866 |
| 69 | AKT3 | 0.56320232 |
| 70 | CSNK1G1 | 0.55899693 |
| 71 | RPS6KA5 | 0.53230284 |
| 72 | NLK | 0.52814175 |
| 73 | CSNK1G3 | 0.51197066 |
| 74 | INSRR | 0.51075829 |
| 75 | MAP2K6 | 0.50628759 |
| 76 | KIT | 0.48546675 |
| 77 | ATM | 0.48541375 |
| 78 | CSNK1A1L | 0.46955399 |
| 79 | KDR | 0.46159823 |
| 80 | IRAK1 | 0.43796575 |
| 81 | CSNK2A1 | 0.42444061 |
| 82 | PIK3CA | 0.41763201 |
| 83 | MYLK | 0.41331236 |
| 84 | CSNK2A2 | 0.40828205 |
| 85 | PRKCE | 0.39022582 |
| 86 | CSNK1G2 | 0.38574198 |
| 87 | PINK1 | 0.36169843 |
| 88 | PRKCQ | 0.36164932 |
| 89 | RPS6KA4 | 0.34291105 |
| 90 | SYK | 0.33768771 |
| 91 | IGF1R | 0.33215694 |
| 92 | MAPK13 | 0.31193904 |
| 93 | DYRK2 | 0.30871182 |
| 94 | DYRK3 | 0.30570451 |
| 95 | BCR | 0.30204841 |
| 96 | CDK7 | 0.30162741 |
| 97 | PRKCG | 0.28466190 |
| 98 | CHEK1 | 0.26260895 |
| 99 | MAPKAPK3 | 0.25918170 |
| 100 | CSNK1E | 0.25435090 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.94304437 |
| 2 | Protein export_Homo sapiens_hsa03060 | 3.00330052 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.86839760 |
| 4 | RNA polymerase_Homo sapiens_hsa03020 | 2.66584125 |
| 5 | Asthma_Homo sapiens_hsa05310 | 2.64722905 |
| 6 | Parkinsons disease_Homo sapiens_hsa05012 | 2.59008977 |
| 7 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.56449850 |
| 8 | Homologous recombination_Homo sapiens_hsa03440 | 2.50448049 |
| 9 | Mismatch repair_Homo sapiens_hsa03430 | 2.33350936 |
| 10 | DNA replication_Homo sapiens_hsa03030 | 2.26070237 |
| 11 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.05729696 |
| 12 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.04075016 |
| 13 | Allograft rejection_Homo sapiens_hsa05330 | 2.03899739 |
| 14 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.95533128 |
| 15 | RNA degradation_Homo sapiens_hsa03018 | 1.93045776 |
| 16 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.91098611 |
| 17 | Ribosome_Homo sapiens_hsa03010 | 1.85421430 |
| 18 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.82760008 |
| 19 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.81426044 |
| 20 | Basal transcription factors_Homo sapiens_hsa03022 | 1.75883301 |
| 21 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.71283458 |
| 22 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.70152929 |
| 23 | RNA transport_Homo sapiens_hsa03013 | 1.68279119 |
| 24 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.67100284 |
| 25 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.63168876 |
| 26 | Huntingtons disease_Homo sapiens_hsa05016 | 1.60562400 |
| 27 | Base excision repair_Homo sapiens_hsa03410 | 1.53603624 |
| 28 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.52748662 |
| 29 | Spliceosome_Homo sapiens_hsa03040 | 1.50132649 |
| 30 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.41643932 |
| 31 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.41179642 |
| 32 | Alzheimers disease_Homo sapiens_hsa05010 | 1.39568921 |
| 33 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.36427222 |
| 34 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.27395685 |
| 35 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.26737954 |
| 36 | Purine metabolism_Homo sapiens_hsa00230 | 1.25913387 |
| 37 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.25290425 |
| 38 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.24503595 |
| 39 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.22043825 |
| 40 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.22002293 |
| 41 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.21146493 |
| 42 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.12580868 |
| 43 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.02215490 |
| 44 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.01615626 |
| 45 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.00627837 |
| 46 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.92415030 |
| 47 | Peroxisome_Homo sapiens_hsa04146 | 0.88412084 |
| 48 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.87266482 |
| 49 | Phototransduction_Homo sapiens_hsa04744 | 0.84567598 |
| 50 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.83692324 |
| 51 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.82797119 |
| 52 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.82250443 |
| 53 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.81279419 |
| 54 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.79338882 |
| 55 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.73332340 |
| 56 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.72066561 |
| 57 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.71035749 |
| 58 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.69751358 |
| 59 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.69732920 |
| 60 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.69732540 |
| 61 | Cell cycle_Homo sapiens_hsa04110 | 0.67692370 |
| 62 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.64331486 |
| 63 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.63909296 |
| 64 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.63469090 |
| 65 | Metabolic pathways_Homo sapiens_hsa01100 | 0.62987235 |
| 66 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.62600431 |
| 67 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.60863483 |
| 68 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.58746963 |
| 69 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.58550688 |
| 70 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.54221300 |
| 71 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.53818799 |
| 72 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.52062987 |
| 73 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.49018748 |
| 74 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.46652834 |
| 75 | Olfactory transduction_Homo sapiens_hsa04740 | 0.45730405 |
| 76 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.44605227 |
| 77 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.44296039 |
| 78 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.43974138 |
| 79 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.43600655 |
| 80 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.42457066 |
| 81 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.41355688 |
| 82 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.41035254 |
| 83 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.41010263 |
| 84 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.40242557 |
| 85 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.38728355 |
| 86 | Carbon metabolism_Homo sapiens_hsa01200 | 0.38199673 |
| 87 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.37781377 |
| 88 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.37023211 |
| 89 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.36585480 |
| 90 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.35389192 |
| 91 | Retinol metabolism_Homo sapiens_hsa00830 | 0.34227999 |
| 92 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.32931623 |
| 93 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.32456583 |
| 94 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.30756531 |
| 95 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.30041001 |
| 96 | Viral myocarditis_Homo sapiens_hsa05416 | 0.29749079 |
| 97 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.29620184 |
| 98 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.27833664 |
| 99 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.27150068 |
| 100 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.26505210 |

