

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | proteasome assembly (GO:0043248) | 5.20361602 |
| 2 | DNA deamination (GO:0045006) | 4.65574962 |
| 3 | ribosome assembly (GO:0042255) | 4.23588760 |
| 4 | rRNA modification (GO:0000154) | 4.20393900 |
| 5 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.06771749 |
| 6 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.99631395 |
| 7 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.95923914 |
| 8 | chaperone-mediated protein transport (GO:0072321) | 3.93794204 |
| 9 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.89973668 |
| 10 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.85730742 |
| 11 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.85048433 |
| 12 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.82312736 |
| 13 | termination of RNA polymerase III transcription (GO:0006386) | 3.82312736 |
| 14 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.77427555 |
| 15 | ATP synthesis coupled proton transport (GO:0015986) | 3.77427555 |
| 16 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.65111601 |
| 17 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.64463770 |
| 18 | rRNA methylation (GO:0031167) | 3.64020756 |
| 19 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.62694610 |
| 20 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.62694610 |
| 21 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.62694610 |
| 22 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.55786732 |
| 23 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.55786732 |
| 24 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.53589918 |
| 25 | ribosomal small subunit assembly (GO:0000028) | 3.50809673 |
| 26 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.49274927 |
| 27 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.44884837 |
| 28 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.44884837 |
| 29 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.44550556 |
| 30 | negative regulation of ligase activity (GO:0051352) | 3.44550556 |
| 31 | DNA double-strand break processing (GO:0000729) | 3.41813904 |
| 32 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.40394772 |
| 33 | protein complex biogenesis (GO:0070271) | 3.35069482 |
| 34 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.33854805 |
| 35 | NADH dehydrogenase complex assembly (GO:0010257) | 3.33854805 |
| 36 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.33854805 |
| 37 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.33378889 |
| 38 | pseudouridine synthesis (GO:0001522) | 3.31687216 |
| 39 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.26581932 |
| 40 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.26111398 |
| 41 | ribosomal large subunit biogenesis (GO:0042273) | 3.25111889 |
| 42 | protein neddylation (GO:0045116) | 3.25084788 |
| 43 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.24265495 |
| 44 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.24265495 |
| 45 | isotype switching (GO:0045190) | 3.24265495 |
| 46 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.22919663 |
| 47 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.19658526 |
| 48 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.19318078 |
| 49 | cullin deneddylation (GO:0010388) | 3.18820312 |
| 50 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.16584410 |
| 51 | respiratory chain complex IV assembly (GO:0008535) | 3.15035700 |
| 52 | chromatin remodeling at centromere (GO:0031055) | 3.12049969 |
| 53 | CENP-A containing nucleosome assembly (GO:0034080) | 3.07368070 |
| 54 | positive regulation of ligase activity (GO:0051351) | 3.06997903 |
| 55 | positive regulation of interleukin-17 production (GO:0032740) | 3.06076948 |
| 56 | protein deneddylation (GO:0000338) | 3.01307187 |
| 57 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.00595493 |
| 58 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.98403689 |
| 59 | IMP biosynthetic process (GO:0006188) | 2.97955850 |
| 60 | protein-cofactor linkage (GO:0018065) | 2.97910168 |
| 61 | regulation of chronic inflammatory response (GO:0002676) | 2.96486356 |
| 62 | cytidine metabolic process (GO:0046087) | 2.93916655 |
| 63 | cytidine catabolic process (GO:0006216) | 2.93916655 |
| 64 | cytidine deamination (GO:0009972) | 2.93916655 |
| 65 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.92200551 |
| 66 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.92200551 |
| 67 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.88265353 |
| 68 | histone mRNA metabolic process (GO:0008334) | 2.87929445 |
| 69 | maturation of 5.8S rRNA (GO:0000460) | 2.87787084 |
| 70 | rRNA processing (GO:0006364) | 2.82007618 |
| 71 | positive regulation of cell cycle arrest (GO:0071158) | 2.81855571 |
| 72 | spliceosomal snRNP assembly (GO:0000387) | 2.80585475 |
| 73 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.79914674 |
| 74 | respiratory electron transport chain (GO:0022904) | 2.79419433 |
| 75 | electron transport chain (GO:0022900) | 2.78983492 |
| 76 | regulation of cellular amine metabolic process (GO:0033238) | 2.78883340 |
| 77 | DNA damage response, detection of DNA damage (GO:0042769) | 2.77636048 |
| 78 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.76752641 |
| 79 | rRNA metabolic process (GO:0016072) | 2.74483325 |
| 80 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.74360585 |
| 81 | purine nucleobase biosynthetic process (GO:0009113) | 2.71768930 |
| 82 | translation (GO:0006412) | 2.71495027 |
| 83 | ribosome biogenesis (GO:0042254) | 2.70232126 |
| 84 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.69382345 |
| 85 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.69382345 |
| 86 | platelet dense granule organization (GO:0060155) | 2.68870760 |
| 87 | regulation of immunoglobulin secretion (GO:0051023) | 2.68595957 |
| 88 | tRNA processing (GO:0008033) | 2.67629054 |
| 89 | nucleobase biosynthetic process (GO:0046112) | 2.67277143 |
| 90 | GTP biosynthetic process (GO:0006183) | 2.66972335 |
| 91 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.66938186 |
| 92 | cytochrome complex assembly (GO:0017004) | 2.66820190 |
| 93 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 2.66763002 |
| 94 | tRNA metabolic process (GO:0006399) | 2.65160082 |
| 95 | protein targeting to mitochondrion (GO:0006626) | 2.64173875 |
| 96 | formation of translation preinitiation complex (GO:0001731) | 2.64147166 |
| 97 | IMP metabolic process (GO:0046040) | 2.63827640 |
| 98 | organelle disassembly (GO:1903008) | 2.61565596 |
| 99 | cellular component biogenesis (GO:0044085) | 2.60082648 |
| 100 | mitochondrial RNA metabolic process (GO:0000959) | 2.58169207 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.02430776 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.44541552 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.79888241 |
| 4 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.13521428 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.07442198 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.06991965 |
| 7 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.95779514 |
| 8 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.92756522 |
| 9 | VDR_22108803_ChIP-Seq_LS180_Human | 2.85763424 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.79790324 |
| 11 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.77990173 |
| 12 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.68161605 |
| 13 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.62295692 |
| 14 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.59203136 |
| 15 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.58172415 |
| 16 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.58033248 |
| 17 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.51907241 |
| 18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.50250947 |
| 19 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.46673497 |
| 20 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.45061777 |
| 21 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.26224577 |
| 22 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.13865331 |
| 23 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.96281379 |
| 24 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.94465373 |
| 25 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.87240759 |
| 26 | EWS_26573619_Chip-Seq_HEK293_Human | 1.84892581 |
| 27 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.83548897 |
| 28 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.81238685 |
| 29 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.80500192 |
| 30 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.74768453 |
| 31 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.74258971 |
| 32 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.69613793 |
| 33 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.69398027 |
| 34 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.68301476 |
| 35 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.65245071 |
| 36 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.59912322 |
| 37 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.59366565 |
| 38 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.55694035 |
| 39 | FUS_26573619_Chip-Seq_HEK293_Human | 1.48858747 |
| 40 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.48782552 |
| 41 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.45214846 |
| 42 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.42439492 |
| 43 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.41373812 |
| 44 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.39473928 |
| 45 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.39378494 |
| 46 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.38964753 |
| 47 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.38017043 |
| 48 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.37997543 |
| 49 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.34197419 |
| 50 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.32499300 |
| 51 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.31142800 |
| 52 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.29408276 |
| 53 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.28514108 |
| 54 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.28514108 |
| 55 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.27109805 |
| 56 | P300_19829295_ChIP-Seq_ESCs_Human | 1.22411612 |
| 57 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.20832682 |
| 58 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.20832682 |
| 59 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.20770801 |
| 60 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.17483513 |
| 61 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.17426020 |
| 62 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.17102639 |
| 63 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.15775627 |
| 64 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.15106064 |
| 65 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.13866259 |
| 66 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.13077096 |
| 67 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.11883194 |
| 68 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.11204529 |
| 69 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.08416228 |
| 70 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.07409148 |
| 71 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.07035131 |
| 72 | AR_20517297_ChIP-Seq_VCAP_Human | 1.06114608 |
| 73 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.05941137 |
| 74 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.05813436 |
| 75 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.05757695 |
| 76 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.04791517 |
| 77 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.04260658 |
| 78 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.03956331 |
| 79 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.03892178 |
| 80 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.03476586 |
| 81 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.03179076 |
| 82 | GATA3_26560356_Chip-Seq_TH2_Human | 1.02560579 |
| 83 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.01136089 |
| 84 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.99071086 |
| 85 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.98825973 |
| 86 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.98668405 |
| 87 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 0.98378344 |
| 88 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.98317253 |
| 89 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.97960706 |
| 90 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.97623602 |
| 91 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.97299310 |
| 92 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.97067961 |
| 93 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.94228354 |
| 94 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.93791341 |
| 95 | NCOR_22424771_ChIP-Seq_293T_Human | 0.93510401 |
| 96 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.92445153 |
| 97 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.92445153 |
| 98 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.91603839 |
| 99 | MYB_26560356_Chip-Seq_TH2_Human | 0.90130086 |
| 100 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.88896234 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001835_abnormal_antigen_presentation | 3.69861171 |
| 2 | MP0002102_abnormal_ear_morphology | 2.80489132 |
| 3 | MP0005671_abnormal_response_to | 2.65857026 |
| 4 | MP0008058_abnormal_DNA_repair | 2.53368328 |
| 5 | MP0010094_abnormal_chromosome_stability | 2.42272473 |
| 6 | MP0006292_abnormal_olfactory_placode | 2.37972145 |
| 7 | MP0003786_premature_aging | 2.37327398 |
| 8 | MP0006072_abnormal_retinal_apoptosis | 2.33741384 |
| 9 | MP0000372_irregular_coat_pigmentation | 2.25521625 |
| 10 | MP0003718_maternal_effect | 2.20991522 |
| 11 | MP0008877_abnormal_DNA_methylation | 2.16112725 |
| 12 | MP0001873_stomach_inflammation | 2.15891205 |
| 13 | MP0003693_abnormal_embryo_hatching | 2.07791727 |
| 14 | MP0005084_abnormal_gallbladder_morpholo | 2.03634196 |
| 15 | MP0008872_abnormal_physiological_respon | 1.98586059 |
| 16 | MP0004957_abnormal_blastocyst_morpholog | 1.95627598 |
| 17 | MP0006036_abnormal_mitochondrial_physio | 1.94837445 |
| 18 | MP0003806_abnormal_nucleotide_metabolis | 1.91256681 |
| 19 | MP0008875_abnormal_xenobiotic_pharmacok | 1.90220260 |
| 20 | MP0008007_abnormal_cellular_replicative | 1.85172394 |
| 21 | MP0002837_dystrophic_cardiac_calcinosis | 1.77529590 |
| 22 | MP0003567_abnormal_fetal_cardiomyocyte | 1.72766591 |
| 23 | MP0009333_abnormal_splenocyte_physiolog | 1.69632098 |
| 24 | MP0004147_increased_porphyrin_level | 1.69552713 |
| 25 | MP0002148_abnormal_hypersensitivity_rea | 1.66080928 |
| 26 | MP0005075_abnormal_melanosome_morpholog | 1.64499381 |
| 27 | MP0003195_calcinosis | 1.60365321 |
| 28 | MP0002736_abnormal_nociception_after | 1.54594255 |
| 29 | MP0001764_abnormal_homeostasis | 1.51286281 |
| 30 | MP0009785_altered_susceptibility_to | 1.50171670 |
| 31 | MP0009697_abnormal_copulation | 1.49226141 |
| 32 | MP0003186_abnormal_redox_activity | 1.46348589 |
| 33 | MP0008057_abnormal_DNA_replication | 1.45743927 |
| 34 | MP0001529_abnormal_vocalization | 1.45448389 |
| 35 | MP0002006_tumorigenesis | 1.45151722 |
| 36 | MP0002163_abnormal_gland_morphology | 1.42774960 |
| 37 | MP0001968_abnormal_touch/_nociception | 1.42114812 |
| 38 | MP0005551_abnormal_eye_electrophysiolog | 1.40081073 |
| 39 | MP0008995_early_reproductive_senescence | 1.38184391 |
| 40 | MP0001293_anophthalmia | 1.37946074 |
| 41 | MP0004145_abnormal_muscle_electrophysio | 1.35653125 |
| 42 | MP0003077_abnormal_cell_cycle | 1.35123116 |
| 43 | MP0002166_altered_tumor_susceptibility | 1.34934838 |
| 44 | MP0000685_abnormal_immune_system | 1.34428007 |
| 45 | MP0003763_abnormal_thymus_physiology | 1.31393373 |
| 46 | MP0001800_abnormal_humoral_immune | 1.31158393 |
| 47 | MP0005645_abnormal_hypothalamus_physiol | 1.29682713 |
| 48 | MP0005389_reproductive_system_phenotype | 1.29404691 |
| 49 | MP0003646_muscle_fatigue | 1.27244197 |
| 50 | MP0005253_abnormal_eye_physiology | 1.26628412 |
| 51 | MP0001188_hyperpigmentation | 1.25623786 |
| 52 | MP0006035_abnormal_mitochondrial_morpho | 1.24407475 |
| 53 | MP0005387_immune_system_phenotype | 1.18172171 |
| 54 | MP0001790_abnormal_immune_system | 1.18172171 |
| 55 | MP0005000_abnormal_immune_tolerance | 1.16130112 |
| 56 | MP0004142_abnormal_muscle_tone | 1.15628873 |
| 57 | MP0005379_endocrine/exocrine_gland_phen | 1.15372084 |
| 58 | MP0002160_abnormal_reproductive_system | 1.14800456 |
| 59 | MP0003111_abnormal_nucleus_morphology | 1.13122453 |
| 60 | MP0003011_delayed_dark_adaptation | 1.09939831 |
| 61 | MP0000465_gastrointestinal_hemorrhage | 1.08876556 |
| 62 | MP0009379_abnormal_foot_pigmentation | 1.08620462 |
| 63 | MP0005408_hypopigmentation | 1.04748153 |
| 64 | MP0002876_abnormal_thyroid_physiology | 1.02580259 |
| 65 | MP0002723_abnormal_immune_serum | 0.94660533 |
| 66 | MP0001986_abnormal_taste_sensitivity | 0.93656078 |
| 67 | MP0001905_abnormal_dopamine_level | 0.91420921 |
| 68 | MP0001929_abnormal_gametogenesis | 0.89441455 |
| 69 | MP0001919_abnormal_reproductive_system | 0.89199308 |
| 70 | MP0002210_abnormal_sex_determination | 0.89131046 |
| 71 | MP0008789_abnormal_olfactory_epithelium | 0.88814616 |
| 72 | MP0000383_abnormal_hair_follicle | 0.88688180 |
| 73 | MP0006082_CNS_inflammation | 0.88068841 |
| 74 | MP0002398_abnormal_bone_marrow | 0.87110768 |
| 75 | MP0000689_abnormal_spleen_morphology | 0.86539848 |
| 76 | MP0002452_abnormal_antigen_presenting | 0.86423342 |
| 77 | MP0001819_abnormal_immune_cell | 0.86277190 |
| 78 | MP0006276_abnormal_autonomic_nervous | 0.85864394 |
| 79 | MP0001119_abnormal_female_reproductive | 0.85456022 |
| 80 | MP0002277_abnormal_respiratory_mucosa | 0.85371211 |
| 81 | MP0005646_abnormal_pituitary_gland | 0.85249833 |
| 82 | MP0002420_abnormal_adaptive_immunity | 0.85088366 |
| 83 | MP0000427_abnormal_hair_cycle | 0.83216966 |
| 84 | MP0005085_abnormal_gallbladder_physiolo | 0.82875117 |
| 85 | MP0004215_abnormal_myocardial_fiber | 0.82223719 |
| 86 | MP0009764_decreased_sensitivity_to | 0.81851720 |
| 87 | MP0001501_abnormal_sleep_pattern | 0.81661544 |
| 88 | MP0005410_abnormal_fertilization | 0.81140082 |
| 89 | MP0001853_heart_inflammation | 0.80840073 |
| 90 | MP0002019_abnormal_tumor_incidence | 0.80811552 |
| 91 | MP0002938_white_spotting | 0.80276662 |
| 92 | MP0004782_abnormal_surfactant_physiolog | 0.79802376 |
| 93 | MP0002095_abnormal_skin_pigmentation | 0.79717233 |
| 94 | MP0008932_abnormal_embryonic_tissue | 0.79664378 |
| 95 | MP0000653_abnormal_sex_gland | 0.79583003 |
| 96 | MP0001145_abnormal_male_reproductive | 0.76389768 |
| 97 | MP0002693_abnormal_pancreas_physiology | 0.73600176 |
| 98 | MP0005636_abnormal_mineral_homeostasis | 0.71655388 |
| 99 | MP0000716_abnormal_immune_system | 0.71482694 |
| 100 | MP0002405_respiratory_system_inflammati | 0.71230107 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.21142697 |
| 2 | Mitochondrial inheritance (HP:0001427) | 3.94085131 |
| 3 | Increased CSF lactate (HP:0002490) | 3.91005285 |
| 4 | Increased hepatocellular lipid droplets (HP:0006565) | 3.75188379 |
| 5 | Hepatocellular necrosis (HP:0001404) | 3.71530079 |
| 6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.66022107 |
| 7 | Acute encephalopathy (HP:0006846) | 3.61569222 |
| 8 | Progressive macrocephaly (HP:0004481) | 3.54459597 |
| 9 | Lipid accumulation in hepatocytes (HP:0006561) | 3.33522878 |
| 10 | Hepatic necrosis (HP:0002605) | 3.33454137 |
| 11 | Aplastic anemia (HP:0001915) | 3.22149242 |
| 12 | Abolished electroretinogram (ERG) (HP:0000550) | 3.18599211 |
| 13 | Cerebral edema (HP:0002181) | 2.97911547 |
| 14 | Methylmalonic acidemia (HP:0002912) | 2.96697239 |
| 15 | Degeneration of anterior horn cells (HP:0002398) | 2.95901817 |
| 16 | Abnormality of the anterior horn cell (HP:0006802) | 2.95901817 |
| 17 | Increased serum lactate (HP:0002151) | 2.93198321 |
| 18 | Stomatitis (HP:0010280) | 2.87874328 |
| 19 | IgG deficiency (HP:0004315) | 2.78639561 |
| 20 | 3-Methylglutaconic aciduria (HP:0003535) | 2.78338676 |
| 21 | Pancreatic cysts (HP:0001737) | 2.77395058 |
| 22 | Reduced antithrombin III activity (HP:0001976) | 2.67190049 |
| 23 | Renal Fanconi syndrome (HP:0001994) | 2.64839885 |
| 24 | Congenital stationary night blindness (HP:0007642) | 2.60435366 |
| 25 | Increased intramyocellular lipid droplets (HP:0012240) | 2.57419636 |
| 26 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.54271988 |
| 27 | Exertional dyspnea (HP:0002875) | 2.48674320 |
| 28 | Abnormality of the prostate (HP:0008775) | 2.48133333 |
| 29 | Lactic acidosis (HP:0003128) | 2.47927661 |
| 30 | Optic disc pallor (HP:0000543) | 2.46467876 |
| 31 | Methylmalonic aciduria (HP:0012120) | 2.44806984 |
| 32 | Type I transferrin isoform profile (HP:0003642) | 2.44597196 |
| 33 | Colon cancer (HP:0003003) | 2.41067535 |
| 34 | Hypoproteinemia (HP:0003075) | 2.38966602 |
| 35 | True hermaphroditism (HP:0010459) | 2.37868745 |
| 36 | Abnormality of midbrain morphology (HP:0002418) | 2.37258462 |
| 37 | Molar tooth sign on MRI (HP:0002419) | 2.37258462 |
| 38 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.36635375 |
| 39 | Abnormality of B cell number (HP:0010975) | 2.34367588 |
| 40 | B lymphocytopenia (HP:0010976) | 2.30072303 |
| 41 | Congenital, generalized hypertrichosis (HP:0004540) | 2.27744180 |
| 42 | Abnormality of the labia minora (HP:0012880) | 2.22979452 |
| 43 | Lethargy (HP:0001254) | 2.22977066 |
| 44 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.22591201 |
| 45 | Hyperglycinemia (HP:0002154) | 2.22228095 |
| 46 | Severe combined immunodeficiency (HP:0004430) | 2.20830664 |
| 47 | Type 2 muscle fiber atrophy (HP:0003554) | 2.19812227 |
| 48 | Leukodystrophy (HP:0002415) | 2.17485811 |
| 49 | Decreased central vision (HP:0007663) | 2.17075301 |
| 50 | Abnormal protein glycosylation (HP:0012346) | 2.16182602 |
| 51 | Abnormal glycosylation (HP:0012345) | 2.16182602 |
| 52 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.16182602 |
| 53 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.16182602 |
| 54 | Nephronophthisis (HP:0000090) | 2.15644506 |
| 55 | Respiratory failure (HP:0002878) | 2.12753414 |
| 56 | Cerebellar dysplasia (HP:0007033) | 2.12257053 |
| 57 | Abnormality of macular pigmentation (HP:0008002) | 2.12025784 |
| 58 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.11488293 |
| 59 | Abnormality of serum amino acid levels (HP:0003112) | 2.08192438 |
| 60 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.06365193 |
| 61 | Pancreatic fibrosis (HP:0100732) | 2.06255344 |
| 62 | Pancytopenia (HP:0001876) | 2.04239719 |
| 63 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.03285818 |
| 64 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.02960147 |
| 65 | Abnormality of glycine metabolism (HP:0010895) | 2.02960147 |
| 66 | Type II lissencephaly (HP:0007260) | 2.01856302 |
| 67 | Multiple enchondromatosis (HP:0005701) | 2.01699952 |
| 68 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.00344146 |
| 69 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.99856985 |
| 70 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.99856985 |
| 71 | Increased muscle lipid content (HP:0009058) | 1.98162658 |
| 72 | Central scotoma (HP:0000603) | 1.98068055 |
| 73 | Exercise intolerance (HP:0003546) | 1.95043816 |
| 74 | Glycosuria (HP:0003076) | 1.93999102 |
| 75 | Abnormality of urine glucose concentration (HP:0011016) | 1.93999102 |
| 76 | Constricted visual fields (HP:0001133) | 1.93297065 |
| 77 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.93270027 |
| 78 | Abnormality of alanine metabolism (HP:0010916) | 1.93270027 |
| 79 | Hyperalaninemia (HP:0003348) | 1.93270027 |
| 80 | Panhypogammaglobulinemia (HP:0003139) | 1.93053183 |
| 81 | Dyschromatopsia (HP:0007641) | 1.91407539 |
| 82 | Thyroiditis (HP:0100646) | 1.90539812 |
| 83 | CNS demyelination (HP:0007305) | 1.89277463 |
| 84 | Abnormality of the pons (HP:0007361) | 1.89084542 |
| 85 | Respiratory difficulties (HP:0002880) | 1.88739261 |
| 86 | Abnormality of methionine metabolism (HP:0010901) | 1.88366247 |
| 87 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.86890889 |
| 88 | Renal cortical cysts (HP:0000803) | 1.86528841 |
| 89 | Hyperglycinuria (HP:0003108) | 1.85975387 |
| 90 | Cerebral palsy (HP:0100021) | 1.85774271 |
| 91 | Hypothermia (HP:0002045) | 1.85739146 |
| 92 | Abnormality of T cells (HP:0002843) | 1.81736492 |
| 93 | Attenuation of retinal blood vessels (HP:0007843) | 1.81068683 |
| 94 | IgM deficiency (HP:0002850) | 1.79958060 |
| 95 | Abnormality of vitamin B metabolism (HP:0004340) | 1.78658964 |
| 96 | Medial flaring of the eyebrow (HP:0010747) | 1.78466724 |
| 97 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.78425070 |
| 98 | Meckel diverticulum (HP:0002245) | 1.77769336 |
| 99 | Muscle fiber atrophy (HP:0100295) | 1.76860948 |
| 100 | Oral leukoplakia (HP:0002745) | 1.74835510 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EIF2AK3 | 3.82360109 |
| 2 | ZAK | 3.55835928 |
| 3 | MST4 | 3.47155617 |
| 4 | VRK2 | 3.22681356 |
| 5 | NUAK1 | 3.01048502 |
| 6 | TSSK6 | 2.66788285 |
| 7 | PBK | 2.50898152 |
| 8 | TXK | 2.40102244 |
| 9 | VRK1 | 2.30444073 |
| 10 | EIF2AK1 | 2.29772789 |
| 11 | BUB1 | 2.23411673 |
| 12 | TAOK3 | 1.93849278 |
| 13 | ADRBK2 | 1.91658219 |
| 14 | CDK19 | 1.88211667 |
| 15 | PLK3 | 1.85362443 |
| 16 | BCKDK | 1.81910103 |
| 17 | GRK1 | 1.81100925 |
| 18 | STK16 | 1.79856872 |
| 19 | MAP4K2 | 1.64580467 |
| 20 | MKNK1 | 1.55598228 |
| 21 | TLK1 | 1.53780178 |
| 22 | WNK3 | 1.49536838 |
| 23 | MAP3K12 | 1.44019257 |
| 24 | NME1 | 1.43167657 |
| 25 | TRIM28 | 1.41915339 |
| 26 | SRPK1 | 1.40832859 |
| 27 | NEK1 | 1.39153033 |
| 28 | OXSR1 | 1.30504981 |
| 29 | MKNK2 | 1.30402850 |
| 30 | PLK4 | 1.28484701 |
| 31 | KDR | 1.25787674 |
| 32 | BRSK2 | 1.24187095 |
| 33 | CSNK1G1 | 1.20202872 |
| 34 | TAF1 | 1.20121514 |
| 35 | EIF2AK2 | 1.16511175 |
| 36 | CDC7 | 1.15662771 |
| 37 | FRK | 1.12786361 |
| 38 | ITK | 1.10352450 |
| 39 | WNK4 | 1.08037838 |
| 40 | DAPK1 | 1.03056038 |
| 41 | BMPR1B | 1.00330215 |
| 42 | PASK | 0.98151685 |
| 43 | TEC | 0.97744722 |
| 44 | BMPR2 | 0.97357063 |
| 45 | CSNK1G3 | 0.92193295 |
| 46 | WEE1 | 0.91824388 |
| 47 | NLK | 0.90404660 |
| 48 | TNIK | 0.88074745 |
| 49 | INSRR | 0.86426431 |
| 50 | PLK1 | 0.83146235 |
| 51 | TESK2 | 0.81841404 |
| 52 | ATR | 0.78061567 |
| 53 | SCYL2 | 0.77326771 |
| 54 | IKBKB | 0.77066371 |
| 55 | BCR | 0.76685354 |
| 56 | CSNK1A1L | 0.74730946 |
| 57 | PLK2 | 0.74288979 |
| 58 | STK39 | 0.74261997 |
| 59 | RPS6KA5 | 0.71686891 |
| 60 | CSNK1G2 | 0.71244874 |
| 61 | TIE1 | 0.70102912 |
| 62 | PINK1 | 0.69924066 |
| 63 | CDK3 | 0.69835855 |
| 64 | TTK | 0.69620040 |
| 65 | PIK3CG | 0.66938966 |
| 66 | MAP2K6 | 0.65976655 |
| 67 | ALK | 0.62519962 |
| 68 | PRKCQ | 0.57379950 |
| 69 | RPS6KA4 | 0.57288190 |
| 70 | DYRK2 | 0.56024404 |
| 71 | AURKB | 0.55164530 |
| 72 | KIT | 0.53038940 |
| 73 | MAP4K1 | 0.51569780 |
| 74 | CSNK2A1 | 0.49586102 |
| 75 | PRKCE | 0.47962869 |
| 76 | ERBB3 | 0.46832928 |
| 77 | ACVR1B | 0.46705014 |
| 78 | CSNK2A2 | 0.46192533 |
| 79 | MYLK | 0.45934624 |
| 80 | IKBKE | 0.45234098 |
| 81 | SYK | 0.44947589 |
| 82 | NME2 | 0.41856573 |
| 83 | CDK6 | 0.40161518 |
| 84 | CAMKK2 | 0.38016673 |
| 85 | LCK | 0.37606057 |
| 86 | ATM | 0.37074416 |
| 87 | MAP3K5 | 0.34630115 |
| 88 | GRK5 | 0.34363536 |
| 89 | ADRBK1 | 0.33926327 |
| 90 | DAPK3 | 0.32751839 |
| 91 | MAP3K4 | 0.32237464 |
| 92 | DAPK2 | 0.30892651 |
| 93 | LYN | 0.30875650 |
| 94 | JAK3 | 0.30851147 |
| 95 | CDK4 | 0.30590953 |
| 96 | CSNK1A1 | 0.30235979 |
| 97 | AURKA | 0.29874178 |
| 98 | MAPKAPK3 | 0.29809015 |
| 99 | FES | 0.28629183 |
| 100 | CSF1R | 0.27081633 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.57781747 |
| 2 | Protein export_Homo sapiens_hsa03060 | 3.06890095 |
| 3 | Asthma_Homo sapiens_hsa05310 | 3.03845820 |
| 4 | Allograft rejection_Homo sapiens_hsa05330 | 2.80933235 |
| 5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.66108071 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.61833561 |
| 7 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.61339439 |
| 8 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.54984925 |
| 9 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.32848032 |
| 10 | Ribosome_Homo sapiens_hsa03010 | 2.28322201 |
| 11 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.26107402 |
| 12 | Mismatch repair_Homo sapiens_hsa03430 | 2.20910151 |
| 13 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.18742511 |
| 14 | Parkinsons disease_Homo sapiens_hsa05012 | 2.16428768 |
| 15 | RNA degradation_Homo sapiens_hsa03018 | 1.96886687 |
| 16 | Homologous recombination_Homo sapiens_hsa03440 | 1.92646815 |
| 17 | DNA replication_Homo sapiens_hsa03030 | 1.89403396 |
| 18 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.85231731 |
| 19 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.82877762 |
| 20 | RNA transport_Homo sapiens_hsa03013 | 1.70612582 |
| 21 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.65856277 |
| 22 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.62915653 |
| 23 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.61259449 |
| 24 | Basal transcription factors_Homo sapiens_hsa03022 | 1.59545130 |
| 25 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.56060064 |
| 26 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.53125395 |
| 27 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.51583164 |
| 28 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.51442764 |
| 29 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.48955731 |
| 30 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.47898351 |
| 31 | Huntingtons disease_Homo sapiens_hsa05016 | 1.38305523 |
| 32 | Spliceosome_Homo sapiens_hsa03040 | 1.37853962 |
| 33 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.37361485 |
| 34 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.33662190 |
| 35 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.25056894 |
| 36 | Alzheimers disease_Homo sapiens_hsa05010 | 1.24894518 |
| 37 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.18999105 |
| 38 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.18938916 |
| 39 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.16555051 |
| 40 | Phototransduction_Homo sapiens_hsa04744 | 1.13723280 |
| 41 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.13483102 |
| 42 | Purine metabolism_Homo sapiens_hsa00230 | 1.11499857 |
| 43 | Base excision repair_Homo sapiens_hsa03410 | 1.11227728 |
| 44 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.03715330 |
| 45 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.02132714 |
| 46 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.97162637 |
| 47 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.92439421 |
| 48 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.90500392 |
| 49 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.85301128 |
| 50 | Peroxisome_Homo sapiens_hsa04146 | 0.82217971 |
| 51 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.81589220 |
| 52 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.79485957 |
| 53 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.79077632 |
| 54 | Viral myocarditis_Homo sapiens_hsa05416 | 0.73823886 |
| 55 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.72868954 |
| 56 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.72080946 |
| 57 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.71707251 |
| 58 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.70588159 |
| 59 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.69916740 |
| 60 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.66116118 |
| 61 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.64662568 |
| 62 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.64510357 |
| 63 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.62266341 |
| 64 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.60907371 |
| 65 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.59861982 |
| 66 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.58751720 |
| 67 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.58157404 |
| 68 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.54076090 |
| 69 | Metabolic pathways_Homo sapiens_hsa01100 | 0.53181023 |
| 70 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.52429354 |
| 71 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.51916073 |
| 72 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.51170242 |
| 73 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.50665156 |
| 74 | Retinol metabolism_Homo sapiens_hsa00830 | 0.50110746 |
| 75 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.48243746 |
| 76 | Olfactory transduction_Homo sapiens_hsa04740 | 0.46911800 |
| 77 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.45939537 |
| 78 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.42926965 |
| 79 | Cell cycle_Homo sapiens_hsa04110 | 0.41991769 |
| 80 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.41808329 |
| 81 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.41661827 |
| 82 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.41245280 |
| 83 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.40070934 |
| 84 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.38614787 |
| 85 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.36925204 |
| 86 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.35482927 |
| 87 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.34897506 |
| 88 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.34655678 |
| 89 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.34353874 |
| 90 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.33069659 |
| 91 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.30432880 |
| 92 | Measles_Homo sapiens_hsa05162 | 0.30124138 |
| 93 | Carbon metabolism_Homo sapiens_hsa01200 | 0.29825662 |
| 94 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.28351747 |
| 95 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.27897016 |
| 96 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.26687774 |
| 97 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.23272150 |
| 98 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.22937247 |
| 99 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.21484946 |
| 100 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.21314402 |

