NPM3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is related to the nuclear chaperone phosphoproteins, nucleoplasmin and nucleophosmin. This protein is strongly expressed in diverse cell types where it localizes primarily to the nucleus. Based on its similarity to nucleoplasmin and nucleophosmin, this protein likely functions as a molecular chaperone in the cell nucleus. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1viral transcription (GO:0019083)6.31713411
2translational termination (GO:0006415)6.14144927
3ribosomal small subunit assembly (GO:0000028)5.94178147
4ribosomal small subunit biogenesis (GO:0042274)5.74127131
5translational elongation (GO:0006414)5.43797391
6maturation of SSU-rRNA (GO:0030490)5.35803461
7nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)5.11921034
8SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.07956990
9translational initiation (GO:0006413)4.98934022
10protein targeting to ER (GO:0045047)4.97248007
11cotranslational protein targeting to membrane (GO:0006613)4.95642887
12ribosomal large subunit biogenesis (GO:0042273)4.80905381
13cellular protein complex disassembly (GO:0043624)4.78711629
14establishment of protein localization to endoplasmic reticulum (GO:0072599)4.74050189
15viral life cycle (GO:0019058)4.73217525
16protein localization to endoplasmic reticulum (GO:0070972)4.62559797
17DNA unwinding involved in DNA replication (GO:0006268)4.54020079
18folic acid-containing compound biosynthetic process (GO:0009396)4.50196600
19protein complex disassembly (GO:0043241)4.36143641
20formation of translation preinitiation complex (GO:0001731)4.31414670
21ribonucleoprotein complex biogenesis (GO:0022613)4.20259096
22DNA strand elongation involved in DNA replication (GO:0006271)4.15313578
23protein localization to kinetochore (GO:0034501)4.14478323
24macromolecular complex disassembly (GO:0032984)4.04851816
25DNA replication initiation (GO:0006270)3.98273517
26proline biosynthetic process (GO:0006561)3.96979870
27DNA strand elongation (GO:0022616)3.92306800
28nuclear-transcribed mRNA catabolic process (GO:0000956)3.88439352
29telomere maintenance via semi-conservative replication (GO:0032201)3.83884812
30DNA replication-dependent nucleosome organization (GO:0034723)3.81305601
31DNA replication-dependent nucleosome assembly (GO:0006335)3.81305601
32nuclear pore organization (GO:0006999)3.77804550
33nuclear pore complex assembly (GO:0051292)3.73415538
34mitotic nuclear envelope disassembly (GO:0007077)3.71676425
35IMP biosynthetic process (GO:0006188)3.71373117
36mRNA catabolic process (GO:0006402)3.69096356
37histone arginine methylation (GO:0034969)3.68356515
38protein localization to chromosome, centromeric region (GO:0071459)3.67852535
39protein complex localization (GO:0031503)3.64411301
40RNA catabolic process (GO:0006401)3.60744469
41nucleobase biosynthetic process (GO:0046112)3.60199501
42nucleobase-containing small molecule interconversion (GO:0015949)3.57632680
43* rRNA processing (GO:0006364)3.52254964
44L-serine metabolic process (GO:0006563)3.51287597
45translation (GO:0006412)3.50676781
46ribosome biogenesis (GO:0042254)3.47589376
47membrane disassembly (GO:0030397)3.42500306
48nuclear envelope disassembly (GO:0051081)3.42500306
49* rRNA metabolic process (GO:0016072)3.41149976
50IMP metabolic process (GO:0046040)3.39921072
51peptidyl-arginine N-methylation (GO:0035246)3.33088769
52peptidyl-arginine methylation (GO:0018216)3.33088769
53telomere maintenance via recombination (GO:0000722)3.32894074
54negative regulation of RNA splicing (GO:0033119)3.32651923
55viral mRNA export from host cell nucleus (GO:0046784)3.32073383
56mitotic sister chromatid segregation (GO:0000070)3.27737908
57DNA deamination (GO:0045006)3.27568652
58ribosome assembly (GO:0042255)3.26670965
59establishment of viral latency (GO:0019043)3.26170071
60protein targeting to membrane (GO:0006612)3.25453329
61regulation of mammary gland epithelial cell proliferation (GO:0033599)3.23707425
62heterochromatin organization (GO:0070828)3.23124642
63protein maturation by protein folding (GO:0022417)3.23029940
64negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.22650032
65cellular protein complex localization (GO:0034629)3.18977330
66mitotic recombination (GO:0006312)3.18782221
67regulation of translational fidelity (GO:0006450)3.17688463
68DNA duplex unwinding (GO:0032508)3.11230991
69spliceosomal snRNP assembly (GO:0000387)3.10263612
70regulation of mitochondrial translation (GO:0070129)3.09811132
71pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.08965254
72DNA geometric change (GO:0032392)3.07574621
73establishment of integrated proviral latency (GO:0075713)3.04251816
74sister chromatid segregation (GO:0000819)3.03274787
75telomere maintenance via telomere lengthening (GO:0010833)3.02409218
76tRNA aminoacylation for protein translation (GO:0006418)3.02094689
77* rRNA transcription (GO:0009303)3.01292845
78ncRNA 3-end processing (GO:0043628)3.01214666
79transcription from mitochondrial promoter (GO:0006390)2.99586707
80pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.99141073
81purine nucleobase biosynthetic process (GO:0009113)2.99031490
82nucleotide-excision repair, DNA gap filling (GO:0006297)2.98713629
83DNA replication checkpoint (GO:0000076)2.98373948
84regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.97408451
85chromatin remodeling at centromere (GO:0031055)2.96968253
86mitochondrial fusion (GO:0008053)2.95432097
87termination of RNA polymerase II transcription (GO:0006369)2.95327209
88regulation of protein heterodimerization activity (GO:0043497)2.93682828
89regulation of histone H3-K9 methylation (GO:0051570)2.92445491
90amino acid activation (GO:0043038)2.92355575
91tRNA aminoacylation (GO:0043039)2.92355575
92base-excision repair (GO:0006284)2.91865388
93pore complex assembly (GO:0046931)2.91865211
94UTP biosynthetic process (GO:0006228)2.90889767
95mitotic chromosome condensation (GO:0007076)2.90857988
96pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.90457214
97guanosine-containing compound biosynthetic process (GO:1901070)2.90246033
98negative regulation of mRNA processing (GO:0050686)2.89710352
99regulation of translational elongation (GO:0006448)2.87593955
100deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.87475754
101mitotic metaphase plate congression (GO:0007080)2.86551331
102CENP-A containing nucleosome assembly (GO:0034080)2.86183487
103regulation of gene silencing by RNA (GO:0060966)2.85864512
104regulation of posttranscriptional gene silencing (GO:0060147)2.85864512
105regulation of gene silencing by miRNA (GO:0060964)2.85864512
106cellular component biogenesis (GO:0044085)2.84618280
107regulation of translational termination (GO:0006449)2.84339618
108pseudouridine synthesis (GO:0001522)2.83733785
109RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.83663912
110mRNA splicing, via spliceosome (GO:0000398)2.83663912
111regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.83479593
112RNA splicing, via transesterification reactions (GO:0000375)2.83477837
113chromatin assembly (GO:0031497)2.81909982
114DNA replication-independent nucleosome assembly (GO:0006336)2.80365710
115DNA replication-independent nucleosome organization (GO:0034724)2.80365710
116negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.80178804
117spliceosomal complex assembly (GO:0000245)2.78962692
118transcription-coupled nucleotide-excision repair (GO:0006283)2.78860929
119chromatin assembly or disassembly (GO:0006333)2.78282082
120peptidyl-arginine omega-N-methylation (GO:0035247)2.70122758
121kinetochore organization (GO:0051383)2.70015271
122pteridine-containing compound biosynthetic process (GO:0042559)2.69695616
123tetrahydrofolate metabolic process (GO:0046653)2.69276171
124negative regulation of mRNA metabolic process (GO:1903312)2.69198351
125positive regulation of chromosome segregation (GO:0051984)2.66791281
126nuclear envelope organization (GO:0006998)2.65811280
127spliceosomal tri-snRNP complex assembly (GO:0000244)2.62331772
128DNA conformation change (GO:0071103)2.62179762
1293-UTR-mediated mRNA stabilization (GO:0070935)2.59451804

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.81296590
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.34668686
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.90145664
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.87434208
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.32195464
6MYC_19079543_ChIP-ChIP_MESCs_Mouse3.21677802
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.86867937
8MYC_19030024_ChIP-ChIP_MESCs_Mouse2.72829328
9* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.66940730
10EST1_17652178_ChIP-ChIP_JURKAT_Human2.53845214
11ETS1_20019798_ChIP-Seq_JURKAT_Human2.42730152
12XRN2_22483619_ChIP-Seq_HELA_Human2.39340381
13MYC_22102868_ChIP-Seq_BL_Human2.29097939
14MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.27184264
15GABP_17652178_ChIP-ChIP_JURKAT_Human2.26721263
16CREB1_15753290_ChIP-ChIP_HEK293T_Human2.25695474
17KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.21254240
18NELFA_20434984_ChIP-Seq_ESCs_Mouse2.14305123
19EGR1_19374776_ChIP-ChIP_THP-1_Human2.12788404
20JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.11005834
21SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.10809749
22TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.07322480
23HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.06439831
24CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.02321728
25VDR_23849224_ChIP-Seq_CD4+_Human1.97275009
26ELF1_17652178_ChIP-ChIP_JURKAT_Human1.81407366
27DCP1A_22483619_ChIP-Seq_HELA_Human1.79328624
28FOXP3_21729870_ChIP-Seq_TREG_Human1.79013255
29E2F1_21310950_ChIP-Seq_MCF-7_Human1.77694686
30TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.77420658
31TTF2_22483619_ChIP-Seq_HELA_Human1.76922231
32MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.76371581
33AR_21909140_ChIP-Seq_LNCAP_Human1.76181850
34* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.75170253
35E2F1_18555785_ChIP-Seq_MESCs_Mouse1.72738423
36MYCN_18555785_ChIP-Seq_MESCs_Mouse1.69831462
37POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.68955838
38FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.67789760
39VDR_21846776_ChIP-Seq_THP-1_Human1.63963501
40NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.58870132
41GABP_19822575_ChIP-Seq_HepG2_Human1.57753108
42NANOG_18555785_ChIP-Seq_MESCs_Mouse1.51859688
43TP63_17297297_ChIP-ChIP_HaCaT_Human1.51308201
44TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.49650867
45ZFX_18555785_ChIP-Seq_MESCs_Mouse1.49645544
46SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.47899663
47CIITA_25753668_ChIP-Seq_RAJI_Human1.45599167
48KDM5A_27292631_Chip-Seq_BREAST_Human1.43742700
49STAT3_1855785_ChIP-Seq_MESCs_Mouse1.42843449
50THAP11_20581084_ChIP-Seq_MESCs_Mouse1.42083880
51* ELK1_19687146_ChIP-ChIP_HELA_Human1.41714573
52ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.36168419
53ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.36120675
54ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.35951776
55KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.31516301
56HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.29687437
57SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.26774200
58POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.26343428
59DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.25772434
60HOXB4_20404135_ChIP-ChIP_EML_Mouse1.25347219
61* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.25135339
62PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.24934447
63PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.24622612
64SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.24385398
65* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.23701309
66YY1_21170310_ChIP-Seq_MESCs_Mouse1.23454108
67ERG_20887958_ChIP-Seq_HPC-7_Mouse1.21145822
68PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.19286699
69YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.18123799
70FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.16024379
71CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.13709394
72* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.13152392
73TET1_21451524_ChIP-Seq_MESCs_Mouse1.12561442
74ELK3_25401928_ChIP-Seq_HUVEC_Human1.12477624
75* SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.09794249
76KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.08173152
77TFEB_21752829_ChIP-Seq_HELA_Human1.08067755
78POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.07901131
79KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.06600310
80CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.06529014
81SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.06457039
82SRY_22984422_ChIP-ChIP_TESTIS_Rat1.03408773
83UTX_26944678_Chip-Seq_JUKART_Human1.03380363
84SOX2_18555785_ChIP-Seq_MESCs_Mouse1.02968085
85RACK7_27058665_Chip-Seq_MCF-7_Human1.02855034
86NOTCH1_21737748_ChIP-Seq_TLL_Human1.02441223
87LXR_22292898_ChIP-Seq_THP-1_Human1.01907955
88E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.01401337
89SPI1_23547873_ChIP-Seq_NB4_Human1.01039295
90ATF3_27146783_Chip-Seq_COLON_Human1.00372519
91ESR1_15608294_ChIP-ChIP_MCF-7_Human1.00223462
92TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.99981958
93CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.99664956
94* MAF_26560356_Chip-Seq_TH1_Human0.98704001
95NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.96822553
96CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.96648934
97HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.96090249
98NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.95619952
99FOXP1_21924763_ChIP-Seq_HESCs_Human0.95040097
100TBX5_21415370_ChIP-Seq_HL-1_Mouse0.94474052
101CTCF_18555785_ChIP-Seq_MESCs_Mouse0.94063275
102PADI4_21655091_ChIP-ChIP_MCF-7_Human0.92943495
103KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.92766129
104* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.92741151
105SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.91864780
106MAF_26560356_Chip-Seq_TH2_Human0.91649669
107OCT4_18692474_ChIP-Seq_MEFs_Mouse0.90264841
108ZNF263_19887448_ChIP-Seq_K562_Human0.89939881
109BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.89735383
110TP63_19390658_ChIP-ChIP_HaCaT_Human0.89107771
111* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.88169125
112MYB_26560356_Chip-Seq_TH2_Human0.87855089
113TCF3_18692474_ChIP-Seq_MEFs_Mouse0.87410705
114E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.87402448
115MYB_26560356_Chip-Seq_TH1_Human0.86146447
116CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.85309833
117* MYC_18940864_ChIP-ChIP_HL60_Human0.84782008
118NANOG_21062744_ChIP-ChIP_HESCs_Human0.82702778
119MYB_21317192_ChIP-Seq_ERMYB_Mouse0.82610728
120CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.82590141
121TCF7_22412390_ChIP-Seq_EML_Mouse0.82564302
122SRF_21415370_ChIP-Seq_HL-1_Mouse0.81766107
123ELK1_22589737_ChIP-Seq_MCF10A_Human0.81170109

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.38786999
2MP0004957_abnormal_blastocyst_morpholog4.04763231
3MP0003111_abnormal_nucleus_morphology3.73615596
4MP0010094_abnormal_chromosome_stability3.67946565
5MP0008057_abnormal_DNA_replication3.45312081
6MP0003077_abnormal_cell_cycle3.42373855
7MP0010352_gastrointestinal_tract_polyps2.61970331
8MP0008007_abnormal_cellular_replicative2.34231356
9MP0008058_abnormal_DNA_repair2.33075196
10MP0002396_abnormal_hematopoietic_system2.30084700
11MP0001730_embryonic_growth_arrest2.28341749
12MP0010234_abnormal_vibrissa_follicle2.22952543
13MP0000350_abnormal_cell_proliferation2.16071240
14MP0008932_abnormal_embryonic_tissue2.13798592
15MP0010307_abnormal_tumor_latency2.05719771
16MP0001661_extended_life_span1.99695099
17MP0005451_abnormal_body_composition1.97980758
18MP0004233_abnormal_muscle_weight1.86887747
19MP0000490_abnormal_crypts_of1.83696121
20MP0009333_abnormal_splenocyte_physiolog1.79431514
21MP0003705_abnormal_hypodermis_morpholog1.75778779
22MP0003763_abnormal_thymus_physiology1.75466393
23MP0003786_premature_aging1.72193881
24MP0003123_paternal_imprinting1.67924906
25MP0004808_abnormal_hematopoietic_stem1.67059620
26MP0005076_abnormal_cell_differentiation1.64697161
27MP0000678_abnormal_parathyroid_gland1.63215702
28MP0005380_embryogenesis_phenotype1.62089598
29MP0001672_abnormal_embryogenesis/_devel1.62089598
30MP0002796_impaired_skin_barrier1.62057429
31MP0001697_abnormal_embryo_size1.61901880
32MP0004197_abnormal_fetal_growth/weight/1.59193236
33MP0002080_prenatal_lethality1.55334928
34MP0002019_abnormal_tumor_incidence1.52901130
35MP0003315_abnormal_perineum_morphology1.49895211
36MP0000703_abnormal_thymus_morphology1.49486511
37MP0003984_embryonic_growth_retardation1.47480924
38MP0002085_abnormal_embryonic_tissue1.46350931
39MP0002088_abnormal_embryonic_growth/wei1.45308886
40MP0002398_abnormal_bone_marrow1.42888311
41MP0002084_abnormal_developmental_patter1.42770461
42MP0000313_abnormal_cell_death1.42654772
43MP0002086_abnormal_extraembryonic_tissu1.42433835
44MP0003806_abnormal_nucleotide_metabolis1.38147201
45MP0006035_abnormal_mitochondrial_morpho1.37758944
46MP0002722_abnormal_immune_system1.34846363
47MP0003941_abnormal_skin_development1.32528554
48MP0002163_abnormal_gland_morphology1.31869373
49MP0005397_hematopoietic_system_phenotyp1.31434861
50MP0001545_abnormal_hematopoietic_system1.31434861
51MP0002254_reproductive_system_inflammat1.31211752
52MP0006292_abnormal_olfactory_placode1.29481282
53MP0000689_abnormal_spleen_morphology1.26216278
54MP0002697_abnormal_eye_size1.25370193
55MP0000858_altered_metastatic_potential1.24126731
56MP0003567_abnormal_fetal_cardiomyocyte1.24054735
57MP0009379_abnormal_foot_pigmentation1.21700357
58MP0009278_abnormal_bone_marrow1.19597638
59MP0010030_abnormal_orbit_morphology1.18807742
60MP0008877_abnormal_DNA_methylation1.16063745
61MP0000685_abnormal_immune_system1.15359629
62MP0005023_abnormal_wound_healing1.10738952
63MP0002429_abnormal_blood_cell1.08299211
64MP0001800_abnormal_humoral_immune1.05236850
65MP0002405_respiratory_system_inflammati1.05202414
66MP0009697_abnormal_copulation1.04964551
67MP0003566_abnormal_cell_adhesion1.04165342
68MP0000762_abnormal_tongue_morphology1.03870044
69MP0000716_abnormal_immune_system1.01547497
70MP0002089_abnormal_postnatal_growth/wei0.98519605
71MP0001346_abnormal_lacrimal_gland0.97309375
72MP0006054_spinal_hemorrhage0.97254764
73MP0002210_abnormal_sex_determination0.97186621
74MP0005257_abnormal_intraocular_pressure0.96027386
75MP0003436_decreased_susceptibility_to0.94819261
76MP0009053_abnormal_anal_canal0.94464544
77MP0001915_intracranial_hemorrhage0.93532522
78MP0003453_abnormal_keratinocyte_physiol0.93114704
79MP0001293_anophthalmia0.92264802
80MP0000358_abnormal_cell_content/0.91486949
81MP0003937_abnormal_limbs/digits/tail_de0.91144837
82MP0001145_abnormal_male_reproductive0.90724849
83MP0002234_abnormal_pharynx_morphology0.89548164
84MP0005501_abnormal_skin_physiology0.89477285
85MP0002420_abnormal_adaptive_immunity0.89146865
86MP0003718_maternal_effect0.88937049
87MP0001853_heart_inflammation0.87859942
88MP0005666_abnormal_adipose_tissue0.87836663
89MP0003303_peritoneal_inflammation0.87597030
90MP0001819_abnormal_immune_cell0.86790631
91MP0000049_abnormal_middle_ear0.86544188
92MP0000537_abnormal_urethra_morphology0.86037020
93MP0001929_abnormal_gametogenesis0.85855960
94MP0002166_altered_tumor_susceptibility0.85221725
95MP0001849_ear_inflammation0.84634653
96MP0002111_abnormal_tail_morphology0.84205445
97MP0002452_abnormal_antigen_presenting0.84039995
98MP0003448_altered_tumor_morphology0.82270530
99MP0001727_abnormal_embryo_implantation0.81841168
100MP0003890_abnormal_embryonic-extraembry0.81513385
101MP0002723_abnormal_immune_serum0.80078521
102MP0003385_abnormal_body_wall0.79976175
103MP0006036_abnormal_mitochondrial_physio0.79922378
104MP0008260_abnormal_autophagy0.79827769
105MP0002877_abnormal_melanocyte_morpholog0.78988170
106MP0000733_abnormal_muscle_development0.78834485
107MP0000477_abnormal_intestine_morphology0.78078292
108MP0000750_abnormal_muscle_regeneration0.77490818
109MP0002249_abnormal_larynx_morphology0.76174396
110MP0000465_gastrointestinal_hemorrhage0.75947928
111MP0002132_abnormal_respiratory_system0.75939505
112MP0009672_abnormal_birth_weight0.74946174
113MP0001348_abnormal_lacrimal_gland0.74444918
114MP0001216_abnormal_epidermal_layer0.73992329
115MP0001835_abnormal_antigen_presentation0.73762972
116MP0002092_abnormal_eye_morphology0.73652487
117MP0002060_abnormal_skin_morphology0.73507858
118MP0010155_abnormal_intestine_physiology0.72197863
119MP0002006_tumorigenesis0.71278649
120MP0005671_abnormal_response_to0.71031617
121MP0003942_abnormal_urinary_system0.70883042
122MP0003300_gastrointestinal_ulcer0.70504845
123MP0001881_abnormal_mammary_gland0.70504659
124MP0000653_abnormal_sex_gland0.70374461
125MP0005384_cellular_phenotype0.69266543
126MP0000428_abnormal_craniofacial_morphol0.69248763
127MP0001873_stomach_inflammation0.69048057
128MP0002160_abnormal_reproductive_system0.68492901
129MP0003186_abnormal_redox_activity0.67943255
130MP0004185_abnormal_adipocyte_glucose0.67935116
131MP0005621_abnormal_cell_physiology0.67508294
132MP0003221_abnormal_cardiomyocyte_apopto0.67461643
133MP0005000_abnormal_immune_tolerance0.66844957
134MP0004858_abnormal_nervous_system0.66381056
135MP0001286_abnormal_eye_development0.66142514
136MP0005025_abnormal_response_to0.65462449
137MP0000003_abnormal_adipose_tissue0.65454420
138MP0005058_abnormal_lysosome_morphology0.63452626
139MP0005623_abnormal_meninges_morphology0.62596141

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)6.59711760
2Reticulocytopenia (HP:0001896)6.16922555
3Abnormal number of erythroid precursors (HP:0012131)5.75444976
4Macrocytic anemia (HP:0001972)4.25886221
5Pallor (HP:0000980)4.14292969
6Microvesicular hepatic steatosis (HP:0001414)3.69565463
7Selective tooth agenesis (HP:0001592)3.64515978
8Thrombocytosis (HP:0001894)3.24803655
9Ependymoma (HP:0002888)3.08078295
10Basal cell carcinoma (HP:0002671)3.06863581
11Multiple enchondromatosis (HP:0005701)3.06277713
12Colon cancer (HP:0003003)2.92578042
13Absent thumb (HP:0009777)2.92440210
14Birth length less than 3rd percentile (HP:0003561)2.89929908
15Progressive external ophthalmoplegia (HP:0000590)2.82883741
16Trismus (HP:0000211)2.76519136
17Oral leukoplakia (HP:0002745)2.76300316
18Hyperacusis (HP:0010780)2.72491607
1911 pairs of ribs (HP:0000878)2.71582944
20Insomnia (HP:0100785)2.71302353
21Abnormality of reticulocytes (HP:0004312)2.70376074
22Breast hypoplasia (HP:0003187)2.68595875
23Squamous cell carcinoma (HP:0002860)2.63628032
24Aplastic anemia (HP:0001915)2.62746358
25Ragged-red muscle fibers (HP:0003200)2.60127918
26Medulloblastoma (HP:0002885)2.54042080
27Chromsome breakage (HP:0040012)2.49191270
28Missing ribs (HP:0000921)2.49154867
29Agnosia (HP:0010524)2.42903407
30Spastic diplegia (HP:0001264)2.42826179
31Myelodysplasia (HP:0002863)2.41207246
32Degeneration of anterior horn cells (HP:0002398)2.35050005
33Abnormality of the anterior horn cell (HP:0006802)2.35050005
34Abnormal number of incisors (HP:0011064)2.34262067
35Nasal polyposis (HP:0100582)2.31752157
36Rhabdomyosarcoma (HP:0002859)2.30136828
37Asplenia (HP:0001746)2.25144085
38Chromosomal breakage induced by crosslinking agents (HP:0003221)2.25126588
39IgM deficiency (HP:0002850)2.24210049
40Broad distal phalanx of finger (HP:0009836)2.22610661
41Neoplasm of the pancreas (HP:0002894)2.22346662
42Carpal bone hypoplasia (HP:0001498)2.20699970
43Deviation of the thumb (HP:0009603)2.19275427
44Cutaneous melanoma (HP:0012056)2.18489490
45Patellar aplasia (HP:0006443)2.18385863
46Proximal placement of thumb (HP:0009623)2.18009712
47Achilles tendon contracture (HP:0001771)2.17863813
48Abnormality of chromosome stability (HP:0003220)2.17822683
49Rough bone trabeculation (HP:0100670)2.15204195
50Cholecystitis (HP:0001082)2.12400139
51Abnormal gallbladder physiology (HP:0012438)2.12400139
52Meckel diverticulum (HP:0002245)2.12210375
53Testicular atrophy (HP:0000029)2.10491648
54Atresia of the external auditory canal (HP:0000413)2.09293411
55Premature skin wrinkling (HP:0100678)2.05268284
56Facial cleft (HP:0002006)2.05014651
57Abnormality of the ileum (HP:0001549)2.04635369
58Aplasia/Hypoplasia of the spleen (HP:0010451)2.04147370
59Abnormality of the umbilical cord (HP:0010881)2.04139334
60Amaurosis fugax (HP:0100576)2.03884903
61Poikiloderma (HP:0001029)2.02864499
62Aplasia/Hypoplasia of the patella (HP:0006498)2.01488342
63Premature graying of hair (HP:0002216)2.00862893
64Increased density of long bones (HP:0006392)2.00622031
65Abnormal trabecular bone morphology (HP:0100671)2.00548523
66Hypergonadotropic hypogonadism (HP:0000815)2.00043713
67Overriding aorta (HP:0002623)1.99944401
68Absent radius (HP:0003974)1.98860519
69High anterior hairline (HP:0009890)1.96720058
70Abnormality of the preputium (HP:0100587)1.96671019
71Long palpebral fissure (HP:0000637)1.96084066
72T lymphocytopenia (HP:0005403)1.95452328
73Microglossia (HP:0000171)1.95353162
74Abnormality of glycolysis (HP:0004366)1.94725551
75Abnormal hemoglobin (HP:0011902)1.94618432
76Premature ovarian failure (HP:0008209)1.94100435
77Nephroblastoma (Wilms tumor) (HP:0002667)1.93633099
78Entropion (HP:0000621)1.92512027
79Microretrognathia (HP:0000308)1.92103850
80Sparse lateral eyebrow (HP:0005338)1.91273208
81Prominent nose (HP:0000448)1.91111524
82Abnormality of T cells (HP:0002843)1.90630144
83Truncus arteriosus (HP:0001660)1.90425050
84Elfin facies (HP:0004428)1.89300483
85Astrocytoma (HP:0009592)1.88753077
86Abnormality of the astrocytes (HP:0100707)1.88753077
87Progressive muscle weakness (HP:0003323)1.88531965
88Increased hepatocellular lipid droplets (HP:0006565)1.88163385
89Glossoptosis (HP:0000162)1.88143745
90High pitched voice (HP:0001620)1.88099143
91Increased nuchal translucency (HP:0010880)1.87445426
92Abnormality of the calcaneus (HP:0008364)1.87045577
93Lymphoma (HP:0002665)1.87021575
94Aplasia/hypoplasia of the humerus (HP:0006507)1.86589175
95Cellular immunodeficiency (HP:0005374)1.85795243
96Duplicated collecting system (HP:0000081)1.85011104
97Tracheoesophageal fistula (HP:0002575)1.84966563
98Bone marrow hypocellularity (HP:0005528)1.84459643
99Aplasia/Hypoplasia of the sacrum (HP:0008517)1.84111320
100Angiofibromas (HP:0010615)1.83816688
101Adenoma sebaceum (HP:0009720)1.83816688
102Neoplasm of striated muscle (HP:0009728)1.83704028
103Renal duplication (HP:0000075)1.81872860
104Redundant skin (HP:0001582)1.81642534
105Abnormality of the Achilles tendon (HP:0005109)1.81057203
106Impulsivity (HP:0100710)1.80335598
107Duplication of thumb phalanx (HP:0009942)1.79183841
108Abnormality of T cell number (HP:0011839)1.78735839
109Absent forearm bone (HP:0003953)1.78716608
110Aplasia involving forearm bones (HP:0009822)1.78716608
111Preauricular skin tag (HP:0000384)1.78054600
112Aplasia/Hypoplasia of the uvula (HP:0010293)1.77790070
113Abnormality of the nasal mucosa (HP:0000433)1.77745496
114Unilateral renal agenesis (HP:0000122)1.77522078
115Respiratory difficulties (HP:0002880)1.76430147
116Pancytopenia (HP:0001876)1.76191407
117Skin tags (HP:0010609)1.76058792
118Depressed nasal ridge (HP:0000457)1.73920619
119Embryonal renal neoplasm (HP:0011794)1.73401221
120Abnormalities of placenta or umbilical cord (HP:0001194)1.72791505
121Abnormal ventriculo-arterial connection (HP:0011563)1.72432505
122Transposition of the great arteries (HP:0001669)1.72432505
123Abnormal connection of the cardiac segments (HP:0011545)1.72432505
124Septate vagina (HP:0001153)1.70132550
125Hypochromic anemia (HP:0001931)1.69922632
126Increased serum lactate (HP:0002151)1.69372801
127Abnormality of pyrimidine metabolism (HP:0004353)1.69156450
128Abnormality of T cell physiology (HP:0011840)1.69149281
129Lipid accumulation in hepatocytes (HP:0006561)1.69028852
130Increased intramyocellular lipid droplets (HP:0012240)1.68845867
131Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.68525502
132Gout (HP:0001997)1.68491501
133Horseshoe kidney (HP:0000085)1.67995116
134Combined immunodeficiency (HP:0005387)1.67817046
135Cafe-au-lait spot (HP:0000957)1.67556657
136Secondary amenorrhea (HP:0000869)1.67398792
137Pseudobulbar signs (HP:0002200)1.66977896
138Type I transferrin isoform profile (HP:0003642)1.66666049
139Recurrent bronchitis (HP:0002837)1.66311631
140Duodenal stenosis (HP:0100867)1.65598776
141Small intestinal stenosis (HP:0012848)1.65598776
142Abnormal lung lobation (HP:0002101)1.65418082
143Abnormality of the distal phalanges of the toes (HP:0010182)1.65189391
144Sloping forehead (HP:0000340)1.63765750
145Facial hemangioma (HP:0000329)1.63214962
146Cerebral hypomyelination (HP:0006808)1.63153115
147Upper motor neuron abnormality (HP:0002127)1.61710888
148Deep palmar crease (HP:0006191)1.60839009
149Sparse eyelashes (HP:0000653)1.59925843
150Abnormality of cochlea (HP:0000375)1.59530207
151Cleft eyelid (HP:0000625)1.59526654
152Capillary hemangiomas (HP:0005306)1.59196404
153Decreased activity of mitochondrial respiratory chain (HP:0008972)1.58330953
154Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.58330953
155Sensory axonal neuropathy (HP:0003390)1.58173401
156Ureteral duplication (HP:0000073)1.58055709
157Abnormality of subcutaneous fat tissue (HP:0001001)1.58012139
158Neoplasm of the adrenal cortex (HP:0100641)1.57464096
159Leiomyosarcoma (HP:0100243)1.56941642
160Uterine leiomyosarcoma (HP:0002891)1.56941642
161Abnormality of DNA repair (HP:0003254)1.55862556
162Exercise intolerance (HP:0003546)1.55166025
163Orthostatic hypotension (HP:0001278)1.53303613
164Dysphonia (HP:0001618)1.53276630
165Abnormal mitochondria in muscle tissue (HP:0008316)1.53062610

Predicted kinase interactions (KEA)

RankGene SetZ-score
1SMG13.94293398
2EEF2K3.75433961
3VRK23.59938754
4CDC73.46371938
5BUB13.28377086
6NME23.18801936
7WEE12.95867517
8NEK22.54398701
9RPS6KB22.43632723
10IRAK32.41221261
11PKN22.39911349
12PBK2.32641949
13MAP3K102.27674047
14ZAK2.14394360
15CDK122.14056421
16MAP4K12.06404772
17TAF11.97704163
18ARAF1.97617580
19PASK1.92508541
20EIF2AK11.88503958
21LRRK21.85765388
22SRPK11.85701030
23STK101.80815162
24TESK21.78664529
25TLK11.77079218
26TTK1.69486472
27CDK71.67007080
28BRAF1.59792022
29TRIB31.58419822
30TSSK61.57492327
31RPS6KA41.56568795
32CDK41.49668162
33MAP3K81.49295169
34SCYL21.40269310
35AURKB1.39425743
36PLK11.34186373
37EIF2AK31.31924871
38ATR1.30355268
39PAK41.30299223
40FLT31.30054428
41EPHA21.29517060
42MKNK11.28932977
43GRK61.26465738
44TGFBR11.25847620
45PIM11.23415815
46ALK1.23393705
47PRPF4B1.22602857
48VRK11.21518641
49DYRK31.19135496
50CHEK11.15654166
51NEK11.13630512
52TESK11.12203785
53BRSK21.12015191
54STK41.08793874
55PIM21.05827975
56CHEK21.01622626
57ACVR1B1.01511535
58TAOK20.97306943
59AURKA0.95853727
60ILK0.93886017
61MAP3K90.91383925
62NME10.91345436
63PAK20.88110581
64MKNK20.85738226
65LATS20.85569909
66ZAP700.84526395
67CDK60.84277613
68MST1R0.82530004
69MAP2K30.80329116
70DAPK10.79565466
71MST40.79517415
72CDK20.76411018
73CSNK2A20.76003968
74ATM0.74430558
75CLK10.74254621
76ICK0.73918596
77DAPK30.73683762
78BTK0.73305604
79BCKDK0.72202565
80MAP3K110.72063097
81BMX0.72058282
82MAPKAPK30.71675555
83PAK10.70432204
84PRKCI0.70074350
85PLK40.68735111
86TTN0.68229841
87MTOR0.64820587
88CDK190.64791480
89JAK30.64066923
90RPS6KA50.62290264
91ABL20.62121379
92PLK30.61192091
93SIK10.61138485
94IRAK20.59924914
95CSF1R0.59476402
96STK30.58725419
97KDR0.58704288
98CSNK2A10.56248078
99ERBB40.55687331
100BRSK10.53883433
101TYK20.53688682
102CDK90.53242960
103MAP3K30.52348641
104PDK40.51220747
105PDK30.51220747
106EIF2AK20.51059859
107PRKD30.50999773
108ERN10.50603722
109AKT20.48970790
110IKBKB0.48717061
111CSNK1G30.48621782
112RAF10.47960609
113CDK10.46415965
114BRD40.45159708
115CSK0.43177335
116PTK60.42115875
117CDK11A0.41832230
118MET0.39866553
119STK160.39508626
120LCK0.39364120
121MAP3K130.38593039
122BLK0.38580226
123RPS6KA10.38472649
124MELK0.37945468
125MAPKAPK20.37600449
126ITK0.37298360
127RPS6KA60.36967336
128MAPKAPK50.36932901
129RPS6KL10.36773065
130RPS6KC10.36773065
131MAPK110.36605280
132CSNK1E0.36355052
133CAMK1D0.36281611
134CDK150.34912890
135CSNK1A1L0.34755691
136CDK80.34500582

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.14213410
2DNA replication_Homo sapiens_hsa030304.47970734
3Mismatch repair_Homo sapiens_hsa034303.70151189
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.44918949
5Spliceosome_Homo sapiens_hsa030403.32225814
6One carbon pool by folate_Homo sapiens_hsa006703.05611808
7RNA transport_Homo sapiens_hsa030132.92327956
8RNA polymerase_Homo sapiens_hsa030202.65111783
9Base excision repair_Homo sapiens_hsa034102.62618315
10Nucleotide excision repair_Homo sapiens_hsa034202.53336339
11Proteasome_Homo sapiens_hsa030502.50774678
12Homologous recombination_Homo sapiens_hsa034402.41405737
13Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.28137301
14Cell cycle_Homo sapiens_hsa041102.18947271
15Pyrimidine metabolism_Homo sapiens_hsa002402.12731258
16Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.82605008
17Systemic lupus erythematosus_Homo sapiens_hsa053221.77243746
18Fanconi anemia pathway_Homo sapiens_hsa034601.75536779
19Non-homologous end-joining_Homo sapiens_hsa034501.72694273
20mRNA surveillance pathway_Homo sapiens_hsa030151.71352418
21RNA degradation_Homo sapiens_hsa030181.70551558
22p53 signaling pathway_Homo sapiens_hsa041151.47746937
23Basal transcription factors_Homo sapiens_hsa030221.34496479
24Cyanoamino acid metabolism_Homo sapiens_hsa004601.32092337
25Antigen processing and presentation_Homo sapiens_hsa046121.30267138
26Viral carcinogenesis_Homo sapiens_hsa052031.22175252
27Primary immunodeficiency_Homo sapiens_hsa053401.11985021
28Epstein-Barr virus infection_Homo sapiens_hsa051691.10653598
29Sulfur relay system_Homo sapiens_hsa041221.09600022
30Fructose and mannose metabolism_Homo sapiens_hsa000511.08369409
31Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.06348990
32Biosynthesis of amino acids_Homo sapiens_hsa012301.04532879
33Pentose phosphate pathway_Homo sapiens_hsa000301.02213755
34Pyruvate metabolism_Homo sapiens_hsa006201.01922826
35Herpes simplex infection_Homo sapiens_hsa051681.01348850
36Galactose metabolism_Homo sapiens_hsa000520.99437973
37Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.98240543
38Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.96226940
39Purine metabolism_Homo sapiens_hsa002300.90468058
40Selenocompound metabolism_Homo sapiens_hsa004500.90007314
41HTLV-I infection_Homo sapiens_hsa051660.85491575
42Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.82852726
43Small cell lung cancer_Homo sapiens_hsa052220.82477194
44Cysteine and methionine metabolism_Homo sapiens_hsa002700.79958393
45Parkinsons disease_Homo sapiens_hsa050120.77430279
46Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.73486675
47Legionellosis_Homo sapiens_hsa051340.72390119
48Transcriptional misregulation in cancer_Homo sapiens_hsa052020.70490156
49Drug metabolism - other enzymes_Homo sapiens_hsa009830.69292290
50MicroRNAs in cancer_Homo sapiens_hsa052060.68830360
51Oxidative phosphorylation_Homo sapiens_hsa001900.65764526
52Apoptosis_Homo sapiens_hsa042100.65681475
53Thyroid cancer_Homo sapiens_hsa052160.65539296
54Chronic myeloid leukemia_Homo sapiens_hsa052200.64886513
55Measles_Homo sapiens_hsa051620.64063438
56Acute myeloid leukemia_Homo sapiens_hsa052210.63729121
57Arginine and proline metabolism_Homo sapiens_hsa003300.62994147
58Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.61921127
59NF-kappa B signaling pathway_Homo sapiens_hsa040640.60507625
60Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.59361659
61Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.58623791
62Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.58459206
63Fatty acid elongation_Homo sapiens_hsa000620.56815274
64Alcoholism_Homo sapiens_hsa050340.56541926
65Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.54784936
66Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.54739246
67Carbon metabolism_Homo sapiens_hsa012000.53767611
68Bladder cancer_Homo sapiens_hsa052190.53019306
69Glutathione metabolism_Homo sapiens_hsa004800.51413499
70Hepatitis B_Homo sapiens_hsa051610.50228488
71Notch signaling pathway_Homo sapiens_hsa043300.50192906
72T cell receptor signaling pathway_Homo sapiens_hsa046600.50096511
73Folate biosynthesis_Homo sapiens_hsa007900.49824317
74Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.49774084
75Central carbon metabolism in cancer_Homo sapiens_hsa052300.48827651
76Protein export_Homo sapiens_hsa030600.46315644
77Viral myocarditis_Homo sapiens_hsa054160.46037252
78Shigellosis_Homo sapiens_hsa051310.45401439
79Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.43978911
80Oocyte meiosis_Homo sapiens_hsa041140.43729456
81B cell receptor signaling pathway_Homo sapiens_hsa046620.43065613
82Colorectal cancer_Homo sapiens_hsa052100.42845370
83Alzheimers disease_Homo sapiens_hsa050100.42286362
84Metabolic pathways_Homo sapiens_hsa011000.41456727
85Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.41187840
86Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.40597947
87Arginine biosynthesis_Homo sapiens_hsa002200.40088487
88Sulfur metabolism_Homo sapiens_hsa009200.39071869
89Steroid biosynthesis_Homo sapiens_hsa001000.39022881
90Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.38423265
91Endometrial cancer_Homo sapiens_hsa052130.38005396
92Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.36510791
93N-Glycan biosynthesis_Homo sapiens_hsa005100.36448463
94Hematopoietic cell lineage_Homo sapiens_hsa046400.36108722
95HIF-1 signaling pathway_Homo sapiens_hsa040660.35743751
96Basal cell carcinoma_Homo sapiens_hsa052170.34886643
97Huntingtons disease_Homo sapiens_hsa050160.34177806
98Wnt signaling pathway_Homo sapiens_hsa043100.32615974
99Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.32509679
100Intestinal immune network for IgA production_Homo sapiens_hsa046720.31250724
101TGF-beta signaling pathway_Homo sapiens_hsa043500.30992297
102Leishmaniasis_Homo sapiens_hsa051400.30758634
103Non-small cell lung cancer_Homo sapiens_hsa052230.29415700
104Melanoma_Homo sapiens_hsa052180.28946541
105Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.28628299
106Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.28363218
1072-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.27189110
108Lysine degradation_Homo sapiens_hsa003100.26612649
109Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.26308001
110Prion diseases_Homo sapiens_hsa050200.26272392
111Pathways in cancer_Homo sapiens_hsa052000.25895512
112Vitamin B6 metabolism_Homo sapiens_hsa007500.25887101
113VEGF signaling pathway_Homo sapiens_hsa043700.25765356
114Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.25281840
115Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.25128561
116Leukocyte transendothelial migration_Homo sapiens_hsa046700.24941406
117Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.24610169
118mTOR signaling pathway_Homo sapiens_hsa041500.24499729
119NOD-like receptor signaling pathway_Homo sapiens_hsa046210.24158105
120Prostate cancer_Homo sapiens_hsa052150.24082445
121Insulin signaling pathway_Homo sapiens_hsa049100.23690492
122Influenza A_Homo sapiens_hsa051640.23152692
123Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.23142144
124Jak-STAT signaling pathway_Homo sapiens_hsa046300.23063136
125Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.22536816
126Toxoplasmosis_Homo sapiens_hsa051450.22270808
127Adherens junction_Homo sapiens_hsa045200.22123557
128Hippo signaling pathway_Homo sapiens_hsa043900.21898475
129Pancreatic cancer_Homo sapiens_hsa052120.19574131
130Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.18934739
131RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.18837427
132Graft-versus-host disease_Homo sapiens_hsa053320.18714181

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »