NPY2R

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)7.32313373
2ionotropic glutamate receptor signaling pathway (GO:0035235)6.36293408
3vocalization behavior (GO:0071625)5.91818534
4tongue development (GO:0043586)5.50106702
5glutamate receptor signaling pathway (GO:0007215)5.32817579
6glutamate secretion (GO:0014047)5.23701735
7synaptic vesicle maturation (GO:0016188)5.18325973
8positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.15126759
9synaptic transmission, glutamatergic (GO:0035249)5.04221578
10regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)5.04136857
11regulation of glutamate receptor signaling pathway (GO:1900449)4.96978790
12regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.91354942
13regulation of neuronal synaptic plasticity (GO:0048168)4.87102528
14neurotransmitter-gated ion channel clustering (GO:0072578)4.81422987
15regulation of long-term neuronal synaptic plasticity (GO:0048169)4.65196531
16neuron-neuron synaptic transmission (GO:0007270)4.64714896
17locomotory exploration behavior (GO:0035641)4.63325964
18proline transport (GO:0015824)4.57855185
19neuron cell-cell adhesion (GO:0007158)4.57305928
20protein localization to synapse (GO:0035418)4.50994070
21exploration behavior (GO:0035640)4.49364059
22neuron recognition (GO:0008038)4.42917759
23positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.40389340
24synaptic vesicle exocytosis (GO:0016079)4.27552422
25gamma-aminobutyric acid signaling pathway (GO:0007214)4.22150542
26pyrimidine nucleobase catabolic process (GO:0006208)4.17662159
27neurotransmitter secretion (GO:0007269)4.13074052
28long-term memory (GO:0007616)4.12249302
29* behavioral defense response (GO:0002209)4.10585874
30* behavioral fear response (GO:0001662)4.10585874
31neuronal action potential propagation (GO:0019227)4.10321870
32ovulation cycle (GO:0042698)4.09109168
33estrogen biosynthetic process (GO:0006703)4.01629285
34positive regulation of synapse maturation (GO:0090129)4.01274841
35response to histamine (GO:0034776)3.98496156
36long-term synaptic potentiation (GO:0060291)3.85112891
37regulation of synaptic plasticity (GO:0048167)3.84095216
38* regulation of excitatory postsynaptic membrane potential (GO:0060079)3.80537265
39negative regulation of synaptic transmission, GABAergic (GO:0032229)3.76226710
40membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.73428078
41regulation of synaptic vesicle exocytosis (GO:2000300)3.72461069
42neuronal stem cell maintenance (GO:0097150)3.70476260
43cellular potassium ion homeostasis (GO:0030007)3.70475840
44regulation of male gonad development (GO:2000018)3.69235424
45amyloid precursor protein catabolic process (GO:0042987)3.68604797
46neuromuscular process controlling posture (GO:0050884)3.67716430
47* fear response (GO:0042596)3.66435401
48regulation of synapse structural plasticity (GO:0051823)3.65748020
49regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.65005614
50retinal ganglion cell axon guidance (GO:0031290)3.63530715
51cerebral cortex radially oriented cell migration (GO:0021799)3.62825435
52serotonin receptor signaling pathway (GO:0007210)3.59822171
53transmission of nerve impulse (GO:0019226)3.58840201
54embryonic digestive tract development (GO:0048566)3.57734065
55regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.57594782
56* regulation of postsynaptic membrane potential (GO:0060078)3.56782701
57regulation of synaptic vesicle transport (GO:1902803)3.55257262
58* regulation of synaptic transmission, glutamatergic (GO:0051966)3.49718787
59cerebral cortex cell migration (GO:0021795)3.49269359
60gonadal mesoderm development (GO:0007506)3.49037823
61neurotransmitter transport (GO:0006836)3.48069589
62suckling behavior (GO:0001967)3.45535745
63cell communication by electrical coupling (GO:0010644)3.45397488
64regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.44700857
65membrane depolarization during action potential (GO:0086010)3.41912524
66startle response (GO:0001964)3.41735679
67cerebellar Purkinje cell differentiation (GO:0021702)3.41152679
68positive regulation of membrane potential (GO:0045838)3.40829426
69* negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.39210326
70cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.38150827
71dendrite morphogenesis (GO:0048813)3.37873008
72chemosensory behavior (GO:0007635)3.37736949
73DNA strand renaturation (GO:0000733)3.37457589
74positive regulation of catenin import into nucleus (GO:0035413)3.37397889
75synaptic vesicle docking involved in exocytosis (GO:0016081)3.37251200
76pyrimidine-containing compound transmembrane transport (GO:0072531)3.36559208
77nonmotile primary cilium assembly (GO:0035058)3.35234544
78drinking behavior (GO:0042756)3.34322930
79cell proliferation in forebrain (GO:0021846)3.34200832
80G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.34068243
81positive regulation of synaptic transmission, GABAergic (GO:0032230)3.31874776
82G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.31336297
83axonal fasciculation (GO:0007413)3.31275857
84presynaptic membrane assembly (GO:0097105)3.31136448
85alpha-linolenic acid metabolic process (GO:0036109)3.30593511
86auditory behavior (GO:0031223)3.29180899
87sequestering of actin monomers (GO:0042989)3.28116954
88regulation of synaptic transmission, GABAergic (GO:0032228)3.27687731
89vitamin transmembrane transport (GO:0035461)3.27224429
90positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.25746876
91nucleobase catabolic process (GO:0046113)3.25180808
92calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)3.24794111
93regulation of inositol phosphate biosynthetic process (GO:0010919)3.23356374
94* membrane depolarization (GO:0051899)3.22831061
95regulation of neurotransmitter levels (GO:0001505)3.22250124
96neuronal ion channel clustering (GO:0045161)3.21745564
97synaptic transmission (GO:0007268)3.21378027
98innervation (GO:0060384)3.21092417
99membrane hyperpolarization (GO:0060081)3.20705454
100cellular sodium ion homeostasis (GO:0006883)3.19368404
101positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.19321303
102cerebellar granule cell differentiation (GO:0021707)3.19136662
103regulation of dendritic spine morphogenesis (GO:0061001)3.18515927
104regulation of synapse maturation (GO:0090128)3.18491289
105axon extension involved in axon guidance (GO:0048846)3.17526745
106neuron projection extension involved in neuron projection guidance (GO:1902284)3.17526745
107dendritic spine morphogenesis (GO:0060997)3.15547030
108postsynaptic membrane organization (GO:0001941)3.10829375
109serotonin metabolic process (GO:0042428)3.10197603
110sodium ion export (GO:0071436)3.09636956
111learning (GO:0007612)3.08103772
112positive regulation of dendritic spine morphogenesis (GO:0061003)3.08006259
113digestive tract morphogenesis (GO:0048546)3.07847764
114gamma-aminobutyric acid transport (GO:0015812)3.06948672
115mechanosensory behavior (GO:0007638)3.05922292
116somite development (GO:0061053)3.05877336
117* regulation of synaptic transmission (GO:0050804)3.05080163
118folic acid transport (GO:0015884)3.02838106
119mating behavior (GO:0007617)3.02083903
120synaptic vesicle endocytosis (GO:0048488)3.01567572
121regulation of chemokine-mediated signaling pathway (GO:0070099)3.00292485
122positive regulation of action potential (GO:0045760)3.00260376
123positive regulation of synaptic transmission (GO:0050806)2.97641287
124protein K6-linked ubiquitination (GO:0085020)2.95395415
125negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.95084622
126positive regulation of dendritic spine development (GO:0060999)2.94995065
127presynaptic membrane organization (GO:0097090)2.94468246
128activation of protein kinase A activity (GO:0034199)2.91931495
129clathrin coat assembly (GO:0048268)2.91210347
130regulation of glutamate secretion (GO:0014048)2.90048403
131positive regulation of male gonad development (GO:2000020)2.89523995
132response to pheromone (GO:0019236)2.89004549
133radial glial cell differentiation (GO:0060019)2.88193435
134C4-dicarboxylate transport (GO:0015740)2.88088349
135regulation of vesicle fusion (GO:0031338)2.87677025
136striatum development (GO:0021756)2.86871434
137calcium ion-dependent exocytosis (GO:0017156)2.86487349
138regulation of respiratory system process (GO:0044065)2.86255899
139detection of calcium ion (GO:0005513)2.85915786
140limb development (GO:0060173)2.80800294
141appendage development (GO:0048736)2.80800294
142* regulation of dopamine secretion (GO:0014059)2.77574598
143regulation of cAMP-dependent protein kinase activity (GO:2000479)2.75781802
144limb bud formation (GO:0060174)2.73693248
145regulation of axon guidance (GO:1902667)2.72697715
146negative chemotaxis (GO:0050919)2.69928332
147glucocorticoid biosynthetic process (GO:0006704)2.69189216
148positive regulation of neuroblast proliferation (GO:0002052)2.68764929
149substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.65269750
150substrate-independent telencephalic tangential migration (GO:0021826)2.65269750
151axon ensheathment in central nervous system (GO:0032291)2.63683843
152central nervous system myelination (GO:0022010)2.63683843
153paraxial mesoderm development (GO:0048339)2.61825909
154neurotransmitter uptake (GO:0001504)2.59518370
155axon extension (GO:0048675)2.59387385
156negative regulation of smoothened signaling pathway (GO:0045879)2.57024504
157positive regulation of synapse assembly (GO:0051965)2.56026368
158hippocampus development (GO:0021766)2.54240410
159regulation of non-canonical Wnt signaling pathway (GO:2000050)2.52467699
160regulation of action potential (GO:0098900)2.50777455
161potassium ion import (GO:0010107)2.48787981
162negative regulation of oligodendrocyte differentiation (GO:0048715)2.48187246
163retinal cone cell development (GO:0046549)2.45369089
164platelet dense granule organization (GO:0060155)2.45110737
165regulation of axon extension involved in axon guidance (GO:0048841)2.44094029
166amyloid precursor protein metabolic process (GO:0042982)2.41302377
167homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156)2.40578889
168regulation of oxidative stress-induced neuron death (GO:1903203)2.39817095
169ephrin receptor signaling pathway (GO:0048013)2.39186988
170response to leptin (GO:0044321)2.38712392
171protein import into peroxisome matrix (GO:0016558)2.37401492
172negative regulation of glial cell differentiation (GO:0045686)2.36478700

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.76304221
2GBX2_23144817_ChIP-Seq_PC3_Human3.85449992
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.17010857
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.02967800
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.93174263
6* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.69464468
7* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.62949998
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.62458229
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.62458229
10BP1_19119308_ChIP-ChIP_Hs578T_Human2.62097448
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.56727185
12* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.50604376
13TAF15_26573619_Chip-Seq_HEK293_Human2.49985231
14ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.46422769
15* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.45333213
16SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.43237579
17REST_21632747_ChIP-Seq_MESCs_Mouse2.41383956
18EED_16625203_ChIP-ChIP_MESCs_Mouse2.41374281
19EZH2_27304074_Chip-Seq_ESCs_Mouse2.38983922
20GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.27905923
21CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.26960829
22RARB_27405468_Chip-Seq_BRAIN_Mouse2.26771421
23SALL1_21062744_ChIP-ChIP_HESCs_Human2.20397279
24* EZH2_27294783_Chip-Seq_ESCs_Mouse2.17772556
25CTBP2_25329375_ChIP-Seq_LNCAP_Human2.16328196
26CTBP1_25329375_ChIP-Seq_LNCAP_Human2.12081403
27SUZ12_27294783_Chip-Seq_ESCs_Mouse2.10200253
28E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.03395606
29RNF2_27304074_Chip-Seq_ESCs_Mouse2.02778840
30* REST_18959480_ChIP-ChIP_MESCs_Mouse2.01213003
31DROSHA_22980978_ChIP-Seq_HELA_Human1.93115549
32IKZF1_21737484_ChIP-ChIP_HCT116_Human1.91260425
33SMAD4_21799915_ChIP-Seq_A2780_Human1.90621411
34ZNF274_21170338_ChIP-Seq_K562_Hela1.81897787
35* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.80759242
36P300_19829295_ChIP-Seq_ESCs_Human1.68384583
37SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.68296286
38PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.65518105
39TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.62302031
40BMI1_23680149_ChIP-Seq_NPCS_Mouse1.58476043
41POU5F1_16153702_ChIP-ChIP_HESCs_Human1.58093322
42NR3C1_23031785_ChIP-Seq_PC12_Mouse1.52230124
43SMAD_19615063_ChIP-ChIP_OVARY_Human1.50362511
44MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.50026262
45PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.49731292
46CBX2_27304074_Chip-Seq_ESCs_Mouse1.47199129
47FUS_26573619_Chip-Seq_HEK293_Human1.47071121
48* AR_25329375_ChIP-Seq_VCAP_Human1.44256069
49PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.42676431
50ERG_21242973_ChIP-ChIP_JURKAT_Human1.42302695
51SMAD3_21741376_ChIP-Seq_EPCs_Human1.41598546
52RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.41074812
53TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.40066983
54TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.39021470
55TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.38974478
56* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.38831404
57SOX2_21211035_ChIP-Seq_LN229_Gbm1.38622171
58MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.37760788
59POU3F2_20337985_ChIP-ChIP_501MEL_Human1.35860113
60GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.34759053
61TOP2B_26459242_ChIP-Seq_MCF-7_Human1.32217154
62* PIAS1_25552417_ChIP-Seq_VCAP_Human1.30850175
63RNF2_27304074_Chip-Seq_NSC_Mouse1.29820028
64VDR_22108803_ChIP-Seq_LS180_Human1.29049463
65SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.28109997
66NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.27085541
67RING1B_27294783_Chip-Seq_ESCs_Mouse1.26944335
68KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.24987747
69ER_23166858_ChIP-Seq_MCF-7_Human1.21745116
70JUN_21703547_ChIP-Seq_K562_Human1.21741849
71FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.20174204
72STAT3_23295773_ChIP-Seq_U87_Human1.19978668
73* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.19618741
74STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.16772360
75RBPJ_22232070_ChIP-Seq_NCS_Mouse1.15978118
76IGF1R_20145208_ChIP-Seq_DFB_Human1.15961745
77SOX9_26525672_Chip-Seq_HEART_Mouse1.14576251
78EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.13763422
79CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13095909
80PRDM14_20953172_ChIP-Seq_ESCs_Human1.12388483
81CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.11743724
82AR_21572438_ChIP-Seq_LNCaP_Human1.11668173
83* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.08860870
84AR_19668381_ChIP-Seq_PC3_Human1.08592373
85TCF4_23295773_ChIP-Seq_U87_Human1.07886783
86TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07034855
87POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.07034855
88LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06801891
89UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.04886654
90* SOX2_16153702_ChIP-ChIP_HESCs_Human1.04441797
91ARNT_22903824_ChIP-Seq_MCF-7_Human1.04005287
92P53_22127205_ChIP-Seq_FIBROBLAST_Human1.03876320
93ZNF217_24962896_ChIP-Seq_MCF-7_Human1.01586588
94KDM2B_26808549_Chip-Seq_REH_Human1.01325133
95IRF1_19129219_ChIP-ChIP_H3396_Human1.00906077
96TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.00822660
97RUNX2_22187159_ChIP-Seq_PCA_Human1.00573020
98YAP1_20516196_ChIP-Seq_MESCs_Mouse1.00114544
99AHR_22903824_ChIP-Seq_MCF-7_Human0.99944420
100RING1B_27294783_Chip-Seq_NPCs_Mouse0.99706950
101TP53_18474530_ChIP-ChIP_U2OS_Human0.99684580
102EP300_21415370_ChIP-Seq_HL-1_Mouse0.99165933
103RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.98366233
104NR3C1_21868756_ChIP-Seq_MCF10A_Human0.96176160
105CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.95182498
106WT1_25993318_ChIP-Seq_PODOCYTE_Human0.94271050
107KLF5_20875108_ChIP-Seq_MESCs_Mouse0.94157007
108CDX2_19796622_ChIP-Seq_MESCs_Mouse0.94092272
109EWS_26573619_Chip-Seq_HEK293_Human0.93892871
110TP53_22573176_ChIP-Seq_HFKS_Human0.92041802
111SMAD3_21741376_ChIP-Seq_ESCs_Human0.91910200
112TBX3_20139965_ChIP-Seq_MESCs_Mouse0.90917623
113RXR_22108803_ChIP-Seq_LS180_Human0.90002591
114* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.89767029
115MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.89377598
116MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.88141283
117* NANOG_18555785_Chip-Seq_ESCs_Mouse0.86025634
118* DNAJC2_21179169_ChIP-ChIP_NT2_Human0.85495384
119BCAT_22108803_ChIP-Seq_LS180_Human0.85247913
120FLI1_21867929_ChIP-Seq_TH2_Mouse0.84780419
121* TCF4_22108803_ChIP-Seq_LS180_Human0.84382189
122TAL1_26923725_Chip-Seq_HPCs_Mouse0.83366764

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity7.42978047
2MP0003880_abnormal_central_pattern5.09356781
3MP0003635_abnormal_synaptic_transmissio4.14396192
4MP0002735_abnormal_chemical_nociception3.73942786
5* MP0009745_abnormal_behavioral_response3.60642402
6MP0001968_abnormal_touch/_nociception3.54408868
7* MP0002063_abnormal_learning/memory/cond3.42468009
8MP0009379_abnormal_foot_pigmentation3.28541917
9* MP0002064_seizures3.25964997
10MP0002736_abnormal_nociception_after3.10816440
11* MP0002572_abnormal_emotion/affect_behav2.97350772
12MP0004270_analgesia2.95898414
13MP0005248_abnormal_Harderian_gland2.92270554
14MP0002653_abnormal_ependyma_morphology2.90104978
15MP0010030_abnormal_orbit_morphology2.87132810
16MP0002272_abnormal_nervous_system2.84061814
17MP0002822_catalepsy2.71287201
18MP0009053_abnormal_anal_canal2.60846621
19MP0009046_muscle_twitch2.47435188
20MP0001440_abnormal_grooming_behavior2.37408949
21MP0008877_abnormal_DNA_methylation2.20037609
22* MP0001501_abnormal_sleep_pattern2.11252503
23MP0000566_synostosis2.09843019
24MP0001486_abnormal_startle_reflex2.07262593
25MP0003011_delayed_dark_adaptation2.07179346
26MP0002734_abnormal_mechanical_nocicepti2.05897728
27MP0006276_abnormal_autonomic_nervous2.00566125
28MP0003329_amyloid_beta_deposits1.95937083
29MP0005394_taste/olfaction_phenotype1.95903592
30MP0005499_abnormal_olfactory_system1.95903592
31* MP0002067_abnormal_sensory_capabilities1.93872810
32MP0004858_abnormal_nervous_system1.90074553
33MP0002233_abnormal_nose_morphology1.89785938
34MP0002184_abnormal_innervation1.88274595
35MP0005423_abnormal_somatic_nervous1.87334454
36MP0001970_abnormal_pain_threshold1.86174048
37MP0002733_abnormal_thermal_nociception1.85650407
38MP0008789_abnormal_olfactory_epithelium1.81385484
39MP0000579_abnormal_nail_morphology1.80626925
40MP0001293_anophthalmia1.75327167
41MP0005646_abnormal_pituitary_gland1.67998835
42MP0009780_abnormal_chondrocyte_physiolo1.66972842
43MP0002557_abnormal_social/conspecific_i1.66735837
44MP0000383_abnormal_hair_follicle1.66673892
45MP0008004_abnormal_stomach_pH1.66397549
46MP0002638_abnormal_pupillary_reflex1.64508572
47MP0000955_abnormal_spinal_cord1.62652771
48MP0004811_abnormal_neuron_physiology1.61798773
49MP0003122_maternal_imprinting1.58898831
50MP0003787_abnormal_imprinting1.55005383
51MP0000778_abnormal_nervous_system1.51394724
52MP0003879_abnormal_hair_cell1.46936470
53MP0009384_cardiac_valve_regurgitation1.44419192
54MP0004885_abnormal_endolymph1.41194824
55MP0004924_abnormal_behavior1.37711877
56MP0005386_behavior/neurological_phenoty1.37711877
57MP0000049_abnormal_middle_ear1.36796803
58MP0001905_abnormal_dopamine_level1.36545208
59MP0008569_lethality_at_weaning1.36179738
60MP0004142_abnormal_muscle_tone1.36080960
61MP0002697_abnormal_eye_size1.34950384
62* MP0002882_abnormal_neuron_morphology1.33814702
63* MP0002066_abnormal_motor_capabilities/c1.31191561
64MP0008775_abnormal_heart_ventricle1.30231703
65MP0000751_myopathy1.28502780
66MP0002932_abnormal_joint_morphology1.27366947
67MP0002909_abnormal_adrenal_gland1.26337267
68MP0002234_abnormal_pharynx_morphology1.25535741
69MP0005253_abnormal_eye_physiology1.23484804
70MP0010368_abnormal_lymphatic_system1.23236391
71MP0003136_yellow_coat_color1.22035434
72MP0001286_abnormal_eye_development1.21332307
73MP0003123_paternal_imprinting1.20852263
74MP0001188_hyperpigmentation1.20028541
75MP0003755_abnormal_palate_morphology1.18377201
76MP0005187_abnormal_penis_morphology1.18295557
77MP0003937_abnormal_limbs/digits/tail_de1.17573286
78MP0002876_abnormal_thyroid_physiology1.16793693
79MP0000013_abnormal_adipose_tissue1.15995983
80MP0001984_abnormal_olfaction1.15921324
81MP0000631_abnormal_neuroendocrine_gland1.15505965
82MP0005645_abnormal_hypothalamus_physiol1.11469069
83MP0002938_white_spotting1.11110797
84MP0006072_abnormal_retinal_apoptosis1.08321744
85MP0003633_abnormal_nervous_system1.06291361
86* MP0003861_abnormal_nervous_system1.04983576
87MP0000604_amyloidosis1.03188118
88MP0002249_abnormal_larynx_morphology1.03048000
89MP0010678_abnormal_skin_adnexa1.02899188
90MP0005391_vision/eye_phenotype1.01641933
91MP0003385_abnormal_body_wall1.01545838
92MP0003119_abnormal_digestive_system1.01421666
93MP0005670_abnormal_white_adipose1.01184868
94MP0001502_abnormal_circadian_rhythm0.98388394
95MP0008872_abnormal_physiological_respon0.97749735
96MP0002282_abnormal_trachea_morphology0.96292911
97MP0003631_nervous_system_phenotype0.95514877
98MP0000537_abnormal_urethra_morphology0.95038454
99MP0008874_decreased_physiological_sensi0.93473503
100MP0003634_abnormal_glial_cell0.92798283
101* MP0002069_abnormal_eating/drinking_beha0.92608343
102MP0003075_altered_response_to0.91682917
103MP0005197_abnormal_uvea_morphology0.90903808
104MP0000462_abnormal_digestive_system0.90416577
105MP0005195_abnormal_posterior_eye0.88864591
106MP0001529_abnormal_vocalization0.88111232
107MP0002837_dystrophic_cardiac_calcinosis0.87944372
108MP0009250_abnormal_appendicular_skeleto0.87804067
109* MP0002152_abnormal_brain_morphology0.87616923
110MP0001986_abnormal_taste_sensitivity0.87356219
111MP0000647_abnormal_sebaceous_gland0.86820202
112MP0001963_abnormal_hearing_physiology0.86043214
113MP0000427_abnormal_hair_cycle0.84846893
114MP0000534_abnormal_ureter_morphology0.84649835
115* MP0004085_abnormal_heartbeat0.84418015
116MP0001340_abnormal_eyelid_morphology0.84122431
117MP0005623_abnormal_meninges_morphology0.82979061
118MP0005171_absent_coat_pigmentation0.82903641
119MP0005367_renal/urinary_system_phenotyp0.82061007
120MP0000516_abnormal_urinary_system0.82061007
121MP0000747_muscle_weakness0.80107292
122MP0004484_altered_response_of0.78481183
123MP0002229_neurodegeneration0.78021461
124MP0002092_abnormal_eye_morphology0.75580474
125MP0003632_abnormal_nervous_system0.75453942
126MP0002109_abnormal_limb_morphology0.75009703
127MP0003690_abnormal_glial_cell0.74601334
128MP0004215_abnormal_myocardial_fiber0.73788873
129MP0003938_abnormal_ear_development0.73720753
130MP0003567_abnormal_fetal_cardiomyocyte0.73150647
131MP0004510_myositis0.72721126
132MP0002116_abnormal_craniofacial_bone0.72063399
133* MP0002752_abnormal_somatic_nervous0.71624106
134MP0004742_abnormal_vestibular_system0.68150063
135MP0000749_muscle_degeneration0.67874684
136MP0005535_abnormal_body_temperature0.63990444
137MP0005551_abnormal_eye_electrophysiolog0.62678358
138MP0001664_abnormal_digestion0.62248791
139MP0001177_atelectasis0.61181242
140MP0001299_abnormal_eye_distance/0.59045330
141MP0002751_abnormal_autonomic_nervous0.56823239
142MP0001485_abnormal_pinna_reflex0.55790239
143MP0005595_abnormal_vascular_smooth0.55581717
144MP0005409_darkened_coat_color0.55383868
145MP0010386_abnormal_urinary_bladder0.53042218
146MP0003121_genomic_imprinting0.52552817
147MP0000026_abnormal_inner_ear0.51506898
148MP0004145_abnormal_muscle_electrophysio0.51489271
149MP0000920_abnormal_myelination0.51416890
150MP0006292_abnormal_olfactory_placode0.50515903
151MP0001943_abnormal_respiration0.50144946
152MP0001765_abnormal_ion_homeostasis0.49150159
153MP0003137_abnormal_impulse_conducting0.48251285

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)8.11867188
2Myokymia (HP:0002411)6.12324838
3Atonic seizures (HP:0010819)5.56721389
4Focal seizures (HP:0007359)5.52887168
5Febrile seizures (HP:0002373)5.01688543
6Epileptic encephalopathy (HP:0200134)5.01042344
7Retinal dysplasia (HP:0007973)4.71298985
8Visual hallucinations (HP:0002367)4.67117891
9Absence seizures (HP:0002121)4.61375371
10Dialeptic seizures (HP:0011146)4.45097950
11Generalized tonic-clonic seizures (HP:0002069)4.08907856
12Hyperventilation (HP:0002883)3.90769490
13Abnormality of the phalanges of the 2nd finger (HP:0009541)3.86736816
14Anomalous pulmonary venous return (HP:0010772)3.86628966
15Vitreoretinal degeneration (HP:0000655)3.84757270
16Hypoventilation (HP:0002791)3.56502043
17Progressive cerebellar ataxia (HP:0002073)3.51725612
18Type II lissencephaly (HP:0007260)3.46007820
19Split foot (HP:0001839)3.38519831
20Abnormal social behavior (HP:0012433)3.37134136
21Impaired social interactions (HP:0000735)3.37134136
22Hypoplastic pelvis (HP:0008839)3.36364111
23Calf muscle hypertrophy (HP:0008981)3.32004167
24Poor eye contact (HP:0000817)3.29289415
25Shoulder girdle muscle weakness (HP:0003547)3.28548950
26Amblyopia (HP:0000646)3.28210282
27Abnormality of the pulmonary veins (HP:0011718)3.24187517
28Action tremor (HP:0002345)3.05936309
29Abnormal eating behavior (HP:0100738)3.05868334
30Nephrogenic diabetes insipidus (HP:0009806)3.02153931
31Excessive salivation (HP:0003781)3.01181185
32Drooling (HP:0002307)3.01181185
33Abnormality of the aortic arch (HP:0012303)3.00212103
34Gaze-evoked nystagmus (HP:0000640)2.98973125
35Muscle hypertrophy of the lower extremities (HP:0008968)2.98931629
36Gait imbalance (HP:0002141)2.98442637
37Achilles tendon contracture (HP:0001771)2.96631283
38Broad-based gait (HP:0002136)2.95522602
39Congenital primary aphakia (HP:0007707)2.83965941
40Rib fusion (HP:0000902)2.82974453
41Partial agenesis of the corpus callosum (HP:0001338)2.79654266
42Impaired vibration sensation in the lower limbs (HP:0002166)2.78962788
43Medial flaring of the eyebrow (HP:0010747)2.78939977
44Progressive inability to walk (HP:0002505)2.75332705
45Oligodactyly (HP:0012165)2.71695176
46Abnormality of the Achilles tendon (HP:0005109)2.70246486
47Anophthalmia (HP:0000528)2.70175281
48Pancreatic fibrosis (HP:0100732)2.68347563
49Dysmetria (HP:0001310)2.65442019
50Abnormality of the musculature of the pelvis (HP:0001469)2.61718817
51Abnormality of the hip-girdle musculature (HP:0001445)2.61718817
52Dysdiadochokinesis (HP:0002075)2.56894637
53Large earlobe (HP:0009748)2.55846289
54Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)2.55194102
55Pelvic girdle muscle weakness (HP:0003749)2.55002978
56Limb-girdle muscle atrophy (HP:0003797)2.54543597
57Truncal ataxia (HP:0002078)2.53645733
58Abnormal ciliary motility (HP:0012262)2.53391592
59Epileptiform EEG discharges (HP:0011182)2.51989236
60Anxiety (HP:0000739)2.50065480
61Abnormal lung lobation (HP:0002101)2.49936389
62Postural instability (HP:0002172)2.49491315
63True hermaphroditism (HP:0010459)2.48757409
64Abnormality of the phalanges of the 5th finger (HP:0004213)2.48384120
65Arthropathy (HP:0003040)2.47098371
66Abnormality of the diencephalon (HP:0010662)2.46760862
67Vaginal atresia (HP:0000148)2.45326045
68Renal dysplasia (HP:0000110)2.44864978
69Vertebral clefting (HP:0008428)2.44035841
70Fetal akinesia sequence (HP:0001989)2.42962968
71Supranuclear gaze palsy (HP:0000605)2.42411580
72Delayed gross motor development (HP:0002194)2.42215077
73Cerebral inclusion bodies (HP:0100314)2.41796223
74Mutism (HP:0002300)2.40971031
75Depression (HP:0000716)2.40185834
76Hemiparesis (HP:0001269)2.36702378
77Abnormality of the proximal phalanges of the hand (HP:0009834)2.34006071
78Abnormality of the lower motor neuron (HP:0002366)2.33686319
79Cupped ear (HP:0000378)2.31235955
80Postaxial hand polydactyly (HP:0001162)2.30370010
81Abnormality of the 2nd finger (HP:0004100)2.30319709
82Oligodactyly (hands) (HP:0001180)2.30108934
83Genital tract atresia (HP:0001827)2.28451071
84Renal hypoplasia (HP:0000089)2.28079979
85EEG with generalized epileptiform discharges (HP:0011198)2.27827043
86Absent speech (HP:0001344)2.26693865
87Polyphagia (HP:0002591)2.24144110
88Increased circulating renin level (HP:0000848)2.23948763
89Broad distal phalanx of finger (HP:0009836)2.21166984
90Torticollis (HP:0000473)2.20818180
91Abnormality of the calf musculature (HP:0001430)2.20160729
92Septo-optic dysplasia (HP:0100842)2.17016878
93Postaxial foot polydactyly (HP:0001830)2.15535600
94Stenosis of the external auditory canal (HP:0000402)2.13244639
95Facial hemangioma (HP:0000329)2.12805534
96Hypsarrhythmia (HP:0002521)2.11361689
97Dynein arm defect of respiratory motile cilia (HP:0012255)2.10208297
98Absent/shortened dynein arms (HP:0200106)2.10208297
99Hemiplegia (HP:0002301)2.10184918
100Anterior segment dysgenesis (HP:0007700)2.10066687
101Neurofibrillary tangles (HP:0002185)2.10059388
102Sensorimotor neuropathy (HP:0007141)2.10056645
103Intestinal atresia (HP:0011100)2.09708286
104Pendular nystagmus (HP:0012043)2.08530980
105Urinary bladder sphincter dysfunction (HP:0002839)2.06869602
106Decreased testicular size (HP:0008734)2.05720454
107Broad foot (HP:0001769)2.04766451
108Difficulty climbing stairs (HP:0003551)2.04492233
109Supernumerary spleens (HP:0009799)2.04327234
110Abnormal respiratory motile cilium physiology (HP:0012261)2.04178537
111Optic nerve hypoplasia (HP:0000609)2.04040127
112Decreased circulating renin level (HP:0003351)2.03290813
113Esotropia (HP:0000565)2.03077096
114Cerebellar dysplasia (HP:0007033)2.02617328
115Focal dystonia (HP:0004373)2.02545752
116Hip dysplasia (HP:0001385)2.01458926
117Cutaneous finger syndactyly (HP:0010554)2.00869914
118Frequent falls (HP:0002359)1.99419827
119Insidious onset (HP:0003587)1.99133338
120Termporal pattern (HP:0011008)1.99133338
121Abnormality of salivation (HP:0100755)1.98958289
122Inability to walk (HP:0002540)1.98070853
123Fibular hypoplasia (HP:0003038)1.97321243
124Scanning speech (HP:0002168)1.96903915
125Ankle clonus (HP:0011448)1.95836475
126Increased variability in muscle fiber diameter (HP:0003557)1.95455609
127Limb dystonia (HP:0002451)1.95159701
128Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.94610293
129Blue irides (HP:0000635)1.94375103
130Intention tremor (HP:0002080)1.94148781
131Hypoplasia of the brainstem (HP:0002365)1.93971830
132Aplasia/Hypoplasia of the brainstem (HP:0007362)1.93971830
133Hyperactive renin-angiotensin system (HP:0000841)1.93525228
134Nonprogressive disorder (HP:0003680)1.92851874
135Aplasia/Hypoplasia of the tongue (HP:0010295)1.92430892
136Agitation (HP:0000713)1.92029744
137Diplopia (HP:0000651)1.91113988
138Abnormality of binocular vision (HP:0011514)1.91113988
139Poor coordination (HP:0002370)1.90976275
140Spastic gait (HP:0002064)1.89926095
141Sclerocornea (HP:0000647)1.89013915
142Status epilepticus (HP:0002133)1.87411242
143Widely spaced teeth (HP:0000687)1.87392946
144Abnormality of the corticospinal tract (HP:0002492)1.86918852
145Lissencephaly (HP:0001339)1.86583203
146Annular pancreas (HP:0001734)1.86074719
147Abnormal EKG (HP:0003115)1.85940343
148Hyperthyroidism (HP:0000836)1.85678366
149Hypoplasia of the pons (HP:0012110)1.85016798
150Poor suck (HP:0002033)1.84978536
151Severe muscular hypotonia (HP:0006829)1.84944983
152Ventricular fibrillation (HP:0001663)1.84032809
153Hypoplasia of the ulna (HP:0003022)1.83930064
154Urinary urgency (HP:0000012)1.83493007
155Bradykinesia (HP:0002067)1.83319784
156Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.83000011
157Absent epiphyses (HP:0010577)1.83000011
158Micropenis (HP:0000054)1.82673431
159Pancreatic cysts (HP:0001737)1.82588511
160Incomplete penetrance (HP:0003829)1.82396844
161Aplasia/Hypoplasia of the fibula (HP:0006492)1.82166286
162Hyperglycinemia (HP:0002154)1.81037869
163Flat capital femoral epiphysis (HP:0003370)1.80015187
164Stereotypic behavior (HP:0000733)1.79142406
165Abnormality of the intervertebral disk (HP:0005108)1.78268695
166Delusions (HP:0000746)1.78170571
167Short foot (HP:0001773)1.78093825
168Short 5th finger (HP:0009237)1.76250131
169Bicornuate uterus (HP:0000813)1.75677883
170Occipital encephalocele (HP:0002085)1.75595566
171Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.75586874
172Short 4th metacarpal (HP:0010044)1.74884012
173Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.74884012
174Abnormal biliary tract physiology (HP:0012439)1.74641808
175Bile duct proliferation (HP:0001408)1.74641808
176Abnormality of midbrain morphology (HP:0002418)1.73302941
177Molar tooth sign on MRI (HP:0002419)1.73302941
178Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.72195447
179Amyotrophic lateral sclerosis (HP:0007354)1.72042221
180Narrow nasal bridge (HP:0000446)1.72035457
181Aplasia/Hypoplasia of the lens (HP:0008063)1.71849403
182Cutaneous syndactyly (HP:0012725)1.70437203
183Specific learning disability (HP:0001328)1.69780313
184Failure to thrive in infancy (HP:0001531)1.68234851
185Tracheomalacia (HP:0002779)1.67825982

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK35.75794799
2EPHA44.60449331
3PIK3CA4.19933637
4CASK3.84987174
5ERBB43.61035669
6MAP3K93.03219635
7MINK12.55110447
8BCKDK2.35465832
9NTRK22.29907781
10EPHB22.26104572
11MAP3K42.26096596
12DYRK22.21785011
13KSR22.17092606
14PLK22.12959572
15ARAF2.03047156
16RIPK42.02992799
17MAP2K72.02288570
18MAP3K122.00786049
19PRPF4B1.90505287
20PKN11.88418316
21STK38L1.87357314
22TESK21.83700069
23MAP3K131.75634971
24MARK11.72304986
25NUAK11.68936917
26PRKD31.63261734
27GRK51.61870915
28TNIK1.54351403
29PAK61.53595410
30PTK2B1.52948121
31KSR11.52675322
32PRKCG1.50001440
33STK161.45443860
34MUSK1.43274187
35MAPK131.42889677
36CSNK1G31.38747675
37CDK51.38333991
38DAPK21.37317332
39CAMK2A1.36437536
40MAP2K41.35938212
41DAPK11.35672654
42NTRK11.34928715
43MKNK11.34172663
44PLK31.30458194
45PRKCH1.27936202
46CAMKK11.24867397
47CAMK2B1.24216298
48CSNK1G11.23132656
49FES1.20548217
50SRPK11.20398166
51ERBB21.17068476
52CSNK1A1L1.15827243
53WNK31.14765654
54EPHA31.11817306
55TTK1.10415084
56CAMK11.08623117
57CAMKK21.05290316
58STK381.04434941
59PRKCE1.01997012
60SIK30.98527332
61FER0.96954889
62FRK0.96593209
63RAF10.95029438
64MKNK20.94944617
65AKT30.92275050
66SGK4940.91739499
67SGK2230.91739499
68MAP2K10.91594164
69RPS6KA50.88631361
70LMTK20.86716729
71MAP3K20.86357279
72CAMK40.85352453
73PINK10.83987901
74NME10.82996032
75MET0.82849805
76SIK20.81895248
77SGK20.80264056
78PAK30.79589815
79ZAK0.78460736
80PNCK0.78115020
81SGK10.77736044
82UHMK10.76162558
83TYRO30.76076665
84VRK10.75969074
85PBK0.75573636
86CCNB10.71039751
87STK110.70949414
88ATR0.69717755
89CSNK1A10.69638360
90BRAF0.69012344
91CAMK2D0.68859173
92LATS10.66472565
93CDK180.66064254
94ALK0.65722326
95CDK140.65376477
96MARK20.65189011
97DYRK1A0.64687933
98LATS20.64022591
99CSNK1D0.63170805
100CAMK2G0.61250196
101CDK150.60055338
102MAP3K10.59460620
103FGR0.59211432
104LIMK10.57238015
105PHKG20.56944670
106PHKG10.56944670
107JAK10.56129546
108YES10.55957789
109ROCK20.55742224
110CSNK1G20.55629902
111SGK30.55343714
112MAP3K70.54886729
113NEK10.54826553
114OXSR10.53873042
115PRKCA0.53542566
116NEK60.52740097
117RPS6KA30.52595707
118INSRR0.52417490
119MAPKAPK50.52046382
120PDK10.51901962
121TNK20.51801208
122PLK10.51438876
123PRKCB0.51292743
124CDK11A0.49716763
125BMPR20.49396819
126MOS0.48966360
127TRIM280.46883557
128ADRBK10.46863153
129BCR0.46732904
130FYN0.45415688
131AKT20.43693925
132DMPK0.43525846
133PDPK10.43337790
134CDK30.43278088
135PRKG10.42980179
136VRK20.42877305
137SRC0.42616698
138PRKACA0.42004281
139MAPK150.41844925
140MATK0.41197856
141PRKCZ0.40356790
142WEE10.38694425
143ERBB30.38539907
144ADRBK20.36329271
145CLK10.36300884
146CDK190.36146786
147STK30.36020276
148PRKACB0.35432922
149PRKACG0.34329238
150PLK40.34281497
151GRK60.33564097
152ATM0.33376178
153TIE10.32696105
154MAPK110.31792715

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.79203500
2Synaptic vesicle cycle_Homo sapiens_hsa047213.11207980
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047233.01298369
4GABAergic synapse_Homo sapiens_hsa047272.96549965
5Glutamatergic synapse_Homo sapiens_hsa047242.88561831
6Long-term potentiation_Homo sapiens_hsa047202.88444250
7Circadian entrainment_Homo sapiens_hsa047132.85492283
8Hedgehog signaling pathway_Homo sapiens_hsa043402.59389541
9Morphine addiction_Homo sapiens_hsa050322.54627508
10Steroid biosynthesis_Homo sapiens_hsa001002.45459842
11Olfactory transduction_Homo sapiens_hsa047402.41551100
12Amphetamine addiction_Homo sapiens_hsa050312.40102249
13Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.31329254
14Collecting duct acid secretion_Homo sapiens_hsa049662.22325927
15Salivary secretion_Homo sapiens_hsa049702.12842184
16Taste transduction_Homo sapiens_hsa047422.06645868
17Dopaminergic synapse_Homo sapiens_hsa047282.00791726
18Basal cell carcinoma_Homo sapiens_hsa052172.00508098
19Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.93848392
20Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.88478908
21Insulin secretion_Homo sapiens_hsa049111.87109575
22Long-term depression_Homo sapiens_hsa047301.85167326
23Serotonergic synapse_Homo sapiens_hsa047261.84819420
24Calcium signaling pathway_Homo sapiens_hsa040201.83492868
25Nitrogen metabolism_Homo sapiens_hsa009101.81412789
26Vibrio cholerae infection_Homo sapiens_hsa051101.80449144
27Cholinergic synapse_Homo sapiens_hsa047251.74486255
28Gastric acid secretion_Homo sapiens_hsa049711.65507199
29* Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.62281113
30Aldosterone synthesis and secretion_Homo sapiens_hsa049251.60264244
31Cocaine addiction_Homo sapiens_hsa050301.58676138
32Hippo signaling pathway_Homo sapiens_hsa043901.46141000
33Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.45768979
34Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.44847693
35Propanoate metabolism_Homo sapiens_hsa006401.43650116
36Oxytocin signaling pathway_Homo sapiens_hsa049211.43411316
37Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.41039975
38Renin secretion_Homo sapiens_hsa049241.39162102
39Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.39069205
40Selenocompound metabolism_Homo sapiens_hsa004501.36311638
41Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.29512017
42Primary bile acid biosynthesis_Homo sapiens_hsa001201.28688908
43cAMP signaling pathway_Homo sapiens_hsa040241.25600820
44GnRH signaling pathway_Homo sapiens_hsa049121.22671707
45Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.22563009
46Axon guidance_Homo sapiens_hsa043601.18433405
47Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.14410119
48Pyruvate metabolism_Homo sapiens_hsa006201.12595329
49Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.07134733
50Fatty acid elongation_Homo sapiens_hsa000621.05997987
51Cardiac muscle contraction_Homo sapiens_hsa042601.05912871
52Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.05585156
53Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.04592045
54RNA degradation_Homo sapiens_hsa030181.04404705
55Gap junction_Homo sapiens_hsa045401.01768790
56Ether lipid metabolism_Homo sapiens_hsa005651.00883741
57Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.99437556
58Fatty acid metabolism_Homo sapiens_hsa012120.97553034
59Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.97498475
60Vitamin digestion and absorption_Homo sapiens_hsa049770.96757683
61cGMP-PKG signaling pathway_Homo sapiens_hsa040220.94999811
62Fatty acid biosynthesis_Homo sapiens_hsa000610.94045874
63Estrogen signaling pathway_Homo sapiens_hsa049150.91062411
64Melanogenesis_Homo sapiens_hsa049160.90964655
65Vascular smooth muscle contraction_Homo sapiens_hsa042700.89507712
66Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.87248814
67Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.87009646
68Phosphatidylinositol signaling system_Homo sapiens_hsa040700.85614367
69RNA polymerase_Homo sapiens_hsa030200.85554238
70Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.84042248
71Notch signaling pathway_Homo sapiens_hsa043300.83844400
72Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.83540017
73Type II diabetes mellitus_Homo sapiens_hsa049300.82368547
74ErbB signaling pathway_Homo sapiens_hsa040120.81932062
75Glioma_Homo sapiens_hsa052140.80867288
76ABC transporters_Homo sapiens_hsa020100.79660399
77Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.79344198
78Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.78371836
79Pancreatic secretion_Homo sapiens_hsa049720.77684539
80Arginine biosynthesis_Homo sapiens_hsa002200.77510620
81Fanconi anemia pathway_Homo sapiens_hsa034600.76944479
82Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.76516331
83Peroxisome_Homo sapiens_hsa041460.76222633
84Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.73797933
85Tight junction_Homo sapiens_hsa045300.71985593
86Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.70719359
87Dilated cardiomyopathy_Homo sapiens_hsa054140.69260349
88TGF-beta signaling pathway_Homo sapiens_hsa043500.68834060
89Thyroid hormone synthesis_Homo sapiens_hsa049180.67962931
90Oocyte meiosis_Homo sapiens_hsa041140.67876496
91Phospholipase D signaling pathway_Homo sapiens_hsa040720.67381152
92Sulfur relay system_Homo sapiens_hsa041220.67196062
93Oxidative phosphorylation_Homo sapiens_hsa001900.64556994
94Base excision repair_Homo sapiens_hsa034100.64035193
95Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.60579975
96Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.60418509
97Choline metabolism in cancer_Homo sapiens_hsa052310.60380576
98Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.60362191
99Protein export_Homo sapiens_hsa030600.60244680
100Histidine metabolism_Homo sapiens_hsa003400.60153927
101Tryptophan metabolism_Homo sapiens_hsa003800.59323194
102Steroid hormone biosynthesis_Homo sapiens_hsa001400.59163041
103Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.58786248
104Dorso-ventral axis formation_Homo sapiens_hsa043200.58243169
105Rheumatoid arthritis_Homo sapiens_hsa053230.57589550
106Homologous recombination_Homo sapiens_hsa034400.55302828
107Phototransduction_Homo sapiens_hsa047440.54571349
108Alzheimers disease_Homo sapiens_hsa050100.54537704
109Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.54400353
110MAPK signaling pathway_Homo sapiens_hsa040100.54369852
111Type I diabetes mellitus_Homo sapiens_hsa049400.49266188
112Ras signaling pathway_Homo sapiens_hsa040140.47954655
113Bile secretion_Homo sapiens_hsa049760.47577373
114Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.43886640
115Phagosome_Homo sapiens_hsa041450.43496106
116Arginine and proline metabolism_Homo sapiens_hsa003300.42941219
117Rap1 signaling pathway_Homo sapiens_hsa040150.42468408
118Glucagon signaling pathway_Homo sapiens_hsa049220.42211147
119Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.42040035
120Folate biosynthesis_Homo sapiens_hsa007900.41936703
121Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.40965241
122Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.39886976
123Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.39420247
124mRNA surveillance pathway_Homo sapiens_hsa030150.38708055
125Prion diseases_Homo sapiens_hsa050200.38587830
126Fatty acid degradation_Homo sapiens_hsa000710.37252419
127Neurotrophin signaling pathway_Homo sapiens_hsa047220.36624923
128Mineral absorption_Homo sapiens_hsa049780.34512115
129African trypanosomiasis_Homo sapiens_hsa051430.34416320
130Carbohydrate digestion and absorption_Homo sapiens_hsa049730.33304385
131Ovarian steroidogenesis_Homo sapiens_hsa049130.31902387
132Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.31298991
133Glycerolipid metabolism_Homo sapiens_hsa005610.27850378
134Alcoholism_Homo sapiens_hsa050340.26537263
135Wnt signaling pathway_Homo sapiens_hsa043100.24831994
136Inositol phosphate metabolism_Homo sapiens_hsa005620.23590663
137Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.22019015
138Glycerophospholipid metabolism_Homo sapiens_hsa005640.21673055
139Butanoate metabolism_Homo sapiens_hsa006500.21586161
140VEGF signaling pathway_Homo sapiens_hsa043700.20528620
141Thyroid hormone signaling pathway_Homo sapiens_hsa049190.19259452
142Huntingtons disease_Homo sapiens_hsa050160.18737570
143Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.17500513
144Sphingolipid metabolism_Homo sapiens_hsa006000.16493013
145Sphingolipid signaling pathway_Homo sapiens_hsa040710.16005946
146Parkinsons disease_Homo sapiens_hsa050120.15053984
147Central carbon metabolism in cancer_Homo sapiens_hsa052300.14975408

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