

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | homocysteine metabolic process (GO:0050667) | 7.24977405 |
| 2 | regulation of plasminogen activation (GO:0010755) | 6.72086827 |
| 3 | cysteine metabolic process (GO:0006534) | 6.69560133 |
| 4 | folic acid-containing compound biosynthetic process (GO:0009396) | 6.52858361 |
| 5 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 6.30287741 |
| 6 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 6.30287741 |
| 7 | segment specification (GO:0007379) | 6.14205543 |
| 8 | sulfur amino acid catabolic process (GO:0000098) | 5.91416867 |
| 9 | purine nucleotide salvage (GO:0032261) | 5.85186270 |
| 10 | adenosine metabolic process (GO:0046085) | 5.76539171 |
| 11 | epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198) | 5.72205867 |
| 12 | inner ear receptor cell development (GO:0060119) | 5.25684588 |
| 13 | acrosome assembly (GO:0001675) | 5.24954146 |
| 14 | white fat cell differentiation (GO:0050872) | 4.89363770 |
| 15 | inner mitochondrial membrane organization (GO:0007007) | 4.78408378 |
| 16 | cochlea development (GO:0090102) | 4.71638446 |
| 17 | innervation (GO:0060384) | 4.59428445 |
| 18 | cartilage morphogenesis (GO:0060536) | 4.55418183 |
| 19 | viral transcription (GO:0019083) | 4.46092015 |
| 20 | galactose catabolic process (GO:0019388) | 4.42251974 |
| 21 | negative regulation of DNA biosynthetic process (GO:2000279) | 4.39238147 |
| 22 | translational termination (GO:0006415) | 4.27874354 |
| 23 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.22530711 |
| 24 | NADH dehydrogenase complex assembly (GO:0010257) | 4.22530711 |
| 25 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.22530711 |
| 26 | pteridine-containing compound biosynthetic process (GO:0042559) | 4.15348861 |
| 27 | behavioral response to nicotine (GO:0035095) | 4.09519623 |
| 28 | galactose metabolic process (GO:0006012) | 4.06741432 |
| 29 | cell migration involved in heart development (GO:0060973) | 3.95333615 |
| 30 | alternative mRNA splicing, via spliceosome (GO:0000380) | 3.90961926 |
| 31 | CENP-A containing nucleosome assembly (GO:0034080) | 3.89991354 |
| 32 | negative regulation of catenin import into nucleus (GO:0035414) | 3.84664419 |
| 33 | serine family amino acid catabolic process (GO:0009071) | 3.82225873 |
| 34 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.79269518 |
| 35 | negative regulation of keratinocyte proliferation (GO:0010839) | 3.74445330 |
| 36 | microtubule nucleation (GO:0007020) | 3.73274389 |
| 37 | ribosomal small subunit assembly (GO:0000028) | 3.69400190 |
| 38 | regulation of gonadotropin secretion (GO:0032276) | 3.66892694 |
| 39 | cilium or flagellum-dependent cell motility (GO:0001539) | 3.64627977 |
| 40 | chromatin remodeling at centromere (GO:0031055) | 3.60785310 |
| 41 | otic vesicle formation (GO:0030916) | 3.59368793 |
| 42 | negative regulation of Ras GTPase activity (GO:0034261) | 3.58834591 |
| 43 | IMP biosynthetic process (GO:0006188) | 3.57729431 |
| 44 | histone H4-K12 acetylation (GO:0043983) | 3.53436187 |
| 45 | negative regulation of interleukin-1 beta production (GO:0032691) | 3.49588420 |
| 46 | mitochondrial RNA metabolic process (GO:0000959) | 3.42729391 |
| 47 | epithelial cilium movement (GO:0003351) | 3.40890898 |
| 48 | positive regulation of endothelial cell differentiation (GO:0045603) | 3.38673944 |
| 49 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.35115208 |
| 50 | adult feeding behavior (GO:0008343) | 3.35115172 |
| 51 | protein-chromophore linkage (GO:0018298) | 3.34609447 |
| 52 | cotranslational protein targeting to membrane (GO:0006613) | 3.34049831 |
| 53 | translational elongation (GO:0006414) | 3.33349010 |
| 54 | L-serine metabolic process (GO:0006563) | 3.30131359 |
| 55 | IMP metabolic process (GO:0046040) | 3.28465513 |
| 56 | cellular protein complex disassembly (GO:0043624) | 3.27722232 |
| 57 | rRNA methylation (GO:0031167) | 3.26290973 |
| 58 | protein targeting to ER (GO:0045047) | 3.23254442 |
| 59 | nephron tubule morphogenesis (GO:0072078) | 3.22237112 |
| 60 | nephron epithelium morphogenesis (GO:0072088) | 3.22237112 |
| 61 | protein complex biogenesis (GO:0070271) | 3.20798313 |
| 62 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.20478460 |
| 63 | regulation of branching involved in salivary gland morphogenesis (GO:0060693) | 3.16980989 |
| 64 | regulation of vitamin D biosynthetic process (GO:0060556) | 3.14692812 |
| 65 | tetrahydrofolate metabolic process (GO:0046653) | 3.14610748 |
| 66 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.10834247 |
| 67 | protein-cofactor linkage (GO:0018065) | 3.10277816 |
| 68 | sulfur amino acid biosynthetic process (GO:0000097) | 3.06178324 |
| 69 | spermatid nucleus differentiation (GO:0007289) | 3.06003911 |
| 70 | rRNA modification (GO:0000154) | 3.05554392 |
| 71 | tRNA modification (GO:0006400) | 3.05264588 |
| 72 | mRNA splice site selection (GO:0006376) | 3.04645919 |
| 73 | viral life cycle (GO:0019058) | 3.03656418 |
| 74 | DNA replication-independent nucleosome organization (GO:0034724) | 3.01521021 |
| 75 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.01521021 |
| 76 | folic acid-containing compound metabolic process (GO:0006760) | 2.99125558 |
| 77 | cellular protein complex localization (GO:0034629) | 2.98540362 |
| 78 | behavioral defense response (GO:0002209) | 2.97335696 |
| 79 | behavioral fear response (GO:0001662) | 2.97335696 |
| 80 | interkinetic nuclear migration (GO:0022027) | 2.94911746 |
| 81 | desmosome organization (GO:0002934) | 2.93583403 |
| 82 | chaperone-mediated protein transport (GO:0072321) | 2.92645679 |
| 83 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.92308970 |
| 84 | negative regulation of oligodendrocyte differentiation (GO:0048715) | 2.92222746 |
| 85 | serine family amino acid biosynthetic process (GO:0009070) | 2.92158182 |
| 86 | purine-containing compound salvage (GO:0043101) | 2.91678216 |
| 87 | histone exchange (GO:0043486) | 2.90020783 |
| 88 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.89304592 |
| 89 | regulation of sequestering of triglyceride (GO:0010889) | 2.89246095 |
| 90 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.89112695 |
| 91 | ATP synthesis coupled proton transport (GO:0015986) | 2.89112695 |
| 92 | protein localization to endoplasmic reticulum (GO:0070972) | 2.88325807 |
| 93 | negative regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043518) | 2.87872546 |
| 94 | negative regulation of telomerase activity (GO:0051974) | 2.86207173 |
| 95 | dopaminergic neuron differentiation (GO:0071542) | 2.85692073 |
| 96 | maturation of SSU-rRNA (GO:0030490) | 2.85070893 |
| 97 | GMP metabolic process (GO:0046037) | 2.84913394 |
| 98 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.84621165 |
| 99 | phosphatidylglycerol biosynthetic process (GO:0006655) | 2.82177974 |
| 100 | pattern specification involved in kidney development (GO:0061004) | 11.2691664 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 8.74604093 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.16844678 |
| 3 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.47119222 |
| 4 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.64685502 |
| 5 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.61744507 |
| 6 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.57885747 |
| 7 | FUS_26573619_Chip-Seq_HEK293_Human | 2.45769418 |
| 8 | VDR_22108803_ChIP-Seq_LS180_Human | 2.34657545 |
| 9 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 2.22988770 |
| 10 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.19860224 |
| 11 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.14033071 |
| 12 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.10227186 |
| 13 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.03242224 |
| 14 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.00267022 |
| 15 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.96282059 |
| 16 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.96282059 |
| 17 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.96282059 |
| 18 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.91299184 |
| 19 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.89755449 |
| 20 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.87153863 |
| 21 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.79457290 |
| 22 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.77992664 |
| 23 | EWS_26573619_Chip-Seq_HEK293_Human | 1.77390201 |
| 24 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.71107988 |
| 25 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.68887585 |
| 26 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.66996220 |
| 27 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.65794381 |
| 28 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.61904432 |
| 29 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.59546367 |
| 30 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.57961013 |
| 31 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.57961013 |
| 32 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.54748322 |
| 33 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.53112997 |
| 34 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.48303301 |
| 35 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.44636793 |
| 36 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.42003133 |
| 37 | P300_19829295_ChIP-Seq_ESCs_Human | 1.40527659 |
| 38 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.39353828 |
| 39 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.39170870 |
| 40 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.37450262 |
| 41 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.36844001 |
| 42 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.35514519 |
| 43 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.34302668 |
| 44 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.33663151 |
| 45 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.30120233 |
| 46 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.29480672 |
| 47 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.28804648 |
| 48 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.27968602 |
| 49 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.27647051 |
| 50 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.25312764 |
| 51 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.24685629 |
| 52 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.24104409 |
| 53 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.22217339 |
| 54 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.15390022 |
| 55 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.14253270 |
| 56 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 1.14190933 |
| 57 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.13799055 |
| 58 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.13602679 |
| 59 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.12887190 |
| 60 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.11624256 |
| 61 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.09536430 |
| 62 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.08690931 |
| 63 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.07927837 |
| 64 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.07414265 |
| 65 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.07273401 |
| 66 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.06594958 |
| 67 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.06498993 |
| 68 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.01404377 |
| 69 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.01385884 |
| 70 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.01046515 |
| 71 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.00659964 |
| 72 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.00309892 |
| 73 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.00114392 |
| 74 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.99430384 |
| 75 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.98958331 |
| 76 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.98444088 |
| 77 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.98199746 |
| 78 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.98129829 |
| 79 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.98082834 |
| 80 | NCOR_22424771_ChIP-Seq_293T_Human | 0.97088725 |
| 81 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.96860858 |
| 82 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.96204145 |
| 83 | SOX2_22085726_ChIP-Seq_NPCs_Mouse | 0.95993355 |
| 84 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.95668899 |
| 85 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.95049160 |
| 86 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 0.94042815 |
| 87 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.91378361 |
| 88 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.90858129 |
| 89 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 0.90724027 |
| 90 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.90433369 |
| 91 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.90284909 |
| 92 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.90284909 |
| 93 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.89221181 |
| 94 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 0.89115161 |
| 95 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.88647282 |
| 96 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.87775129 |
| 97 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.86879855 |
| 98 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.86506429 |
| 99 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.86347450 |
| 100 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.81997677 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000566_synostosis | 6.32300410 |
| 2 | MP0000569_abnormal_digit_pigmentation | 6.26341219 |
| 3 | MP0002938_white_spotting | 4.64750836 |
| 4 | MP0003136_yellow_coat_color | 3.81315611 |
| 5 | MP0008995_early_reproductive_senescence | 3.08136432 |
| 6 | MP0005646_abnormal_pituitary_gland | 3.06611175 |
| 7 | MP0005174_abnormal_tail_pigmentation | 2.46508425 |
| 8 | MP0003880_abnormal_central_pattern | 2.46445062 |
| 9 | MP0000516_abnormal_urinary_system | 2.43617261 |
| 10 | MP0005367_renal/urinary_system_phenotyp | 2.43617261 |
| 11 | MP0003705_abnormal_hypodermis_morpholog | 2.31225157 |
| 12 | MP0005360_urolithiasis | 2.29814681 |
| 13 | MP0009379_abnormal_foot_pigmentation | 2.24208359 |
| 14 | MP0003183_abnormal_peptide_metabolism | 2.21984477 |
| 15 | MP0004133_heterotaxia | 2.20999865 |
| 16 | MP0002095_abnormal_skin_pigmentation | 2.06883453 |
| 17 | MP0005670_abnormal_white_adipose | 2.05218137 |
| 18 | MP0000631_abnormal_neuroendocrine_gland | 2.01222787 |
| 19 | MP0004885_abnormal_endolymph | 1.99302935 |
| 20 | MP0003787_abnormal_imprinting | 1.98489566 |
| 21 | MP0002736_abnormal_nociception_after | 1.88140552 |
| 22 | MP0006292_abnormal_olfactory_placode | 1.83788865 |
| 23 | MP0003315_abnormal_perineum_morphology | 1.77529425 |
| 24 | MP0000778_abnormal_nervous_system | 1.56166481 |
| 25 | MP0000013_abnormal_adipose_tissue | 1.47251178 |
| 26 | MP0003806_abnormal_nucleotide_metabolis | 1.46571924 |
| 27 | MP0000371_diluted_coat_color | 1.41819833 |
| 28 | MP0000026_abnormal_inner_ear | 1.41664142 |
| 29 | MP0005551_abnormal_eye_electrophysiolog | 1.36948630 |
| 30 | MP0001984_abnormal_olfaction | 1.36815431 |
| 31 | MP0001968_abnormal_touch/_nociception | 1.36452437 |
| 32 | MP0001293_anophthalmia | 1.35442878 |
| 33 | MP0002277_abnormal_respiratory_mucosa | 1.33391375 |
| 34 | MP0001502_abnormal_circadian_rhythm | 1.32041908 |
| 35 | MP0002653_abnormal_ependyma_morphology | 1.29935873 |
| 36 | MP0001764_abnormal_homeostasis | 1.27402771 |
| 37 | MP0001661_extended_life_span | 1.26037561 |
| 38 | MP0003942_abnormal_urinary_system | 1.22651444 |
| 39 | MP0000534_abnormal_ureter_morphology | 1.21575666 |
| 40 | MP0002876_abnormal_thyroid_physiology | 1.19732164 |
| 41 | MP0010030_abnormal_orbit_morphology | 1.16182039 |
| 42 | MP0000372_irregular_coat_pigmentation | 1.15927868 |
| 43 | MP0002396_abnormal_hematopoietic_system | 1.15343243 |
| 44 | MP0002928_abnormal_bile_duct | 1.14928496 |
| 45 | MP0005171_absent_coat_pigmentation | 1.14503262 |
| 46 | MP0006072_abnormal_retinal_apoptosis | 1.13548615 |
| 47 | MP0001529_abnormal_vocalization | 1.11896693 |
| 48 | MP0001286_abnormal_eye_development | 1.07792832 |
| 49 | MP0002697_abnormal_eye_size | 1.06827872 |
| 50 | MP0002735_abnormal_chemical_nociception | 1.05831981 |
| 51 | MP0000647_abnormal_sebaceous_gland | 1.02298509 |
| 52 | MP0001485_abnormal_pinna_reflex | 1.01794218 |
| 53 | MP0003941_abnormal_skin_development | 1.00590980 |
| 54 | MP0003938_abnormal_ear_development | 1.00371748 |
| 55 | MP0003186_abnormal_redox_activity | 0.97131246 |
| 56 | MP0002282_abnormal_trachea_morphology | 0.97111971 |
| 57 | MP0001919_abnormal_reproductive_system | 0.96931253 |
| 58 | MP0006276_abnormal_autonomic_nervous | 0.96572350 |
| 59 | MP0003567_abnormal_fetal_cardiomyocyte | 0.94238779 |
| 60 | MP0002075_abnormal_coat/hair_pigmentati | 0.94228265 |
| 61 | MP0005377_hearing/vestibular/ear_phenot | 0.91181454 |
| 62 | MP0003878_abnormal_ear_physiology | 0.91181454 |
| 63 | MP0002837_dystrophic_cardiac_calcinosis | 0.90239559 |
| 64 | MP0005084_abnormal_gallbladder_morpholo | 0.89796133 |
| 65 | MP0002234_abnormal_pharynx_morphology | 0.88261380 |
| 66 | MP0003959_abnormal_lean_body | 0.85350948 |
| 67 | MP0002638_abnormal_pupillary_reflex | 0.84180148 |
| 68 | MP0005253_abnormal_eye_physiology | 0.83425499 |
| 69 | MP0005187_abnormal_penis_morphology | 0.83374788 |
| 70 | MP0005332_abnormal_amino_acid | 0.81866945 |
| 71 | MP0002069_abnormal_eating/drinking_beha | 0.75721862 |
| 72 | MP0001963_abnormal_hearing_physiology | 0.74300405 |
| 73 | MP0004142_abnormal_muscle_tone | 0.72335836 |
| 74 | MP0005195_abnormal_posterior_eye | 0.71876686 |
| 75 | MP0001486_abnormal_startle_reflex | 0.70950295 |
| 76 | MP0003121_genomic_imprinting | 0.70597711 |
| 77 | MP0009745_abnormal_behavioral_response | 0.69428678 |
| 78 | MP0002295_abnormal_pulmonary_circulatio | 0.69105751 |
| 79 | MP0002734_abnormal_mechanical_nocicepti | 0.68039663 |
| 80 | MP0003937_abnormal_limbs/digits/tail_de | 0.68031218 |
| 81 | MP0001324_abnormal_eye_pigmentation | 0.67096332 |
| 82 | MP0001186_pigmentation_phenotype | 0.66320955 |
| 83 | MP0009053_abnormal_anal_canal | 0.65804944 |
| 84 | MP0004742_abnormal_vestibular_system | 0.64366999 |
| 85 | MP0009250_abnormal_appendicular_skeleto | 0.64072562 |
| 86 | MP0005248_abnormal_Harderian_gland | 0.63826254 |
| 87 | MP0002971_abnormal_brown_adipose | 0.62902064 |
| 88 | MP0008872_abnormal_physiological_respon | 0.62300497 |
| 89 | MP0003890_abnormal_embryonic-extraembry | 0.60816469 |
| 90 | MP0002752_abnormal_somatic_nervous | 0.60684043 |
| 91 | MP0003936_abnormal_reproductive_system | 0.60460975 |
| 92 | MP0000955_abnormal_spinal_cord | 0.60395004 |
| 93 | MP0002184_abnormal_innervation | 0.59876551 |
| 94 | MP0004147_increased_porphyrin_level | 0.57788809 |
| 95 | MP0009046_muscle_twitch | 0.57466863 |
| 96 | MP0002210_abnormal_sex_determination | 0.57278416 |
| 97 | MP0005410_abnormal_fertilization | 0.57199038 |
| 98 | MP0003698_abnormal_male_reproductive | 0.56781152 |
| 99 | MP0002160_abnormal_reproductive_system | 0.56589779 |
| 100 | MP0001944_abnormal_pancreas_morphology | 0.56145111 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of alanine metabolism (HP:0010916) | 6.54820678 |
| 2 | Hyperalaninemia (HP:0003348) | 6.54820678 |
| 3 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 6.54820678 |
| 4 | Constricted visual fields (HP:0001133) | 5.03844458 |
| 5 | Congenital sensorineural hearing impairment (HP:0008527) | 4.23751959 |
| 6 | Chronic hepatic failure (HP:0100626) | 4.16694136 |
| 7 | Reticulocytopenia (HP:0001896) | 3.92979135 |
| 8 | Maternal diabetes (HP:0009800) | 3.87608216 |
| 9 | Spontaneous hematomas (HP:0007420) | 3.87537666 |
| 10 | Abnormality of the fetal cardiovascular system (HP:0010948) | 3.46428517 |
| 11 | Abnormal umbilical cord blood vessels (HP:0011403) | 3.46428517 |
| 12 | Single umbilical artery (HP:0001195) | 3.46428517 |
| 13 | Septo-optic dysplasia (HP:0100842) | 3.40450305 |
| 14 | Cortical visual impairment (HP:0100704) | 3.39424474 |
| 15 | Esophageal varix (HP:0002040) | 3.18285733 |
| 16 | Hypoplasia of the pons (HP:0012110) | 3.13286764 |
| 17 | Abnormality of the pons (HP:0007361) | 2.98927592 |
| 18 | Abnormality of serum amino acid levels (HP:0003112) | 2.96466545 |
| 19 | Patchy hypopigmentation of hair (HP:0011365) | 2.95479091 |
| 20 | White forelock (HP:0002211) | 2.87459700 |
| 21 | Partial duplication of thumb phalanx (HP:0009944) | 2.85900279 |
| 22 | Duplicated collecting system (HP:0000081) | 2.79954180 |
| 23 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.79561114 |
| 24 | Absent septum pellucidum (HP:0001331) | 2.75846864 |
| 25 | True hermaphroditism (HP:0010459) | 2.74984072 |
| 26 | Birth length less than 3rd percentile (HP:0003561) | 2.69221102 |
| 27 | Pancreatic cysts (HP:0001737) | 2.68404468 |
| 28 | Pancreatic fibrosis (HP:0100732) | 2.67014877 |
| 29 | Chronic otitis media (HP:0000389) | 2.65815256 |
| 30 | Duplication of thumb phalanx (HP:0009942) | 2.63801659 |
| 31 | Abnormality of the renal collecting system (HP:0004742) | 2.58323144 |
| 32 | Poor speech (HP:0002465) | 2.52464455 |
| 33 | Abnormality of homocysteine metabolism (HP:0010919) | 2.51260706 |
| 34 | Homocystinuria (HP:0002156) | 2.51260706 |
| 35 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.50541257 |
| 36 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.50541257 |
| 37 | Midline defect of the nose (HP:0004122) | 2.49108384 |
| 38 | Stenosis of the external auditory canal (HP:0000402) | 2.46525248 |
| 39 | Partial duplication of the phalanx of hand (HP:0009999) | 2.44478379 |
| 40 | Macrocytic anemia (HP:0001972) | 2.39030518 |
| 41 | Action tremor (HP:0002345) | 2.38156687 |
| 42 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.37185081 |
| 43 | Hyperglycinemia (HP:0002154) | 2.32858059 |
| 44 | Hypoplastic left heart (HP:0004383) | 2.30178641 |
| 45 | Abnormal number of erythroid precursors (HP:0012131) | 2.28233531 |
| 46 | Pendular nystagmus (HP:0012043) | 2.28228033 |
| 47 | Small epiphyses (HP:0010585) | 2.26320946 |
| 48 | Abnormality of the septum pellucidum (HP:0007375) | 2.25342545 |
| 49 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.20300138 |
| 50 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.19471612 |
| 51 | Chromsome breakage (HP:0040012) | 2.18997045 |
| 52 | Split foot (HP:0001839) | 2.17449323 |
| 53 | Oligomenorrhea (HP:0000876) | 2.17141966 |
| 54 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 2.15625264 |
| 55 | Bile duct proliferation (HP:0001408) | 2.14401904 |
| 56 | Abnormal biliary tract physiology (HP:0012439) | 2.14401904 |
| 57 | Molar tooth sign on MRI (HP:0002419) | 2.13060854 |
| 58 | Abnormality of midbrain morphology (HP:0002418) | 2.13060854 |
| 59 | Conjunctival telangiectasia (HP:0000524) | 2.11378415 |
| 60 | Anencephaly (HP:0002323) | 2.06579789 |
| 61 | Cystic liver disease (HP:0006706) | 2.03929979 |
| 62 | Gastrointestinal atresia (HP:0002589) | 2.01607777 |
| 63 | Nephronophthisis (HP:0000090) | 2.00662890 |
| 64 | Pallor (HP:0000980) | 2.00193890 |
| 65 | Oligodactyly (hands) (HP:0001180) | 1.98831674 |
| 66 | Chronic sinusitis (HP:0011109) | 1.98511692 |
| 67 | 3-Methylglutaconic aciduria (HP:0003535) | 1.97243172 |
| 68 | Shawl scrotum (HP:0000049) | 1.97234607 |
| 69 | Ectopic anus (HP:0004397) | 1.96217665 |
| 70 | Anophthalmia (HP:0000528) | 1.95875678 |
| 71 | Anorexia (HP:0002039) | 1.95512937 |
| 72 | Visceral angiomatosis (HP:0100761) | 1.95306606 |
| 73 | Ectopic kidney (HP:0000086) | 1.93489907 |
| 74 | Abnormality of the umbilical cord (HP:0010881) | 1.92199762 |
| 75 | Attenuation of retinal blood vessels (HP:0007843) | 1.91810213 |
| 76 | Arteriovenous malformation (HP:0100026) | 1.90577176 |
| 77 | Triphalangeal thumb (HP:0001199) | 1.90526708 |
| 78 | Intestinal atresia (HP:0011100) | 1.89263032 |
| 79 | Absent thumb (HP:0009777) | 1.88941067 |
| 80 | Delayed CNS myelination (HP:0002188) | 1.87422885 |
| 81 | Microcytic anemia (HP:0001935) | 1.86670741 |
| 82 | Meckel diverticulum (HP:0002245) | 1.84245586 |
| 83 | Generalized aminoaciduria (HP:0002909) | 1.82556561 |
| 84 | Hypoplastic heart (HP:0001961) | 1.82277445 |
| 85 | Abnormality of the labia minora (HP:0012880) | 1.82008431 |
| 86 | Esophageal atresia (HP:0002032) | 1.80142790 |
| 87 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.78009226 |
| 88 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.76642921 |
| 89 | Optic nerve coloboma (HP:0000588) | 1.76076935 |
| 90 | Chorioretinal coloboma (HP:0000567) | 1.75953710 |
| 91 | Broad distal phalanx of finger (HP:0009836) | 1.73734925 |
| 92 | Portal hypertension (HP:0001409) | 1.73455393 |
| 93 | Epileptic encephalopathy (HP:0200134) | 1.73049802 |
| 94 | Abnormality of the carotid arteries (HP:0005344) | 1.72608379 |
| 95 | Heterochromia iridis (HP:0001100) | 1.71192235 |
| 96 | Chorioretinal atrophy (HP:0000533) | 1.70279095 |
| 97 | Supernumerary spleens (HP:0009799) | 1.69471041 |
| 98 | Occipital encephalocele (HP:0002085) | 1.66951581 |
| 99 | Hemivertebrae (HP:0002937) | 1.66947387 |
| 100 | Hemangiomatosis (HP:0007461) | 1.66767565 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EPHB2 | 3.76110818 |
| 2 | NTRK2 | 3.57634005 |
| 3 | PIM2 | 3.49270752 |
| 4 | BMPR1B | 3.13890750 |
| 5 | PNCK | 2.72330937 |
| 6 | MAP3K3 | 2.64024658 |
| 7 | VRK2 | 2.55510941 |
| 8 | CDK9 | 2.49318168 |
| 9 | MAP2K3 | 2.48890905 |
| 10 | TNIK | 2.36369336 |
| 11 | DYRK1B | 2.20298067 |
| 12 | ACVR1B | 2.15606644 |
| 13 | TAF1 | 2.08846586 |
| 14 | TGFBR1 | 2.01676251 |
| 15 | PASK | 1.81796103 |
| 16 | NTRK3 | 1.71440411 |
| 17 | SGK223 | 1.70279208 |
| 18 | SGK494 | 1.70279208 |
| 19 | TSSK6 | 1.67057805 |
| 20 | MARK1 | 1.63147365 |
| 21 | DYRK2 | 1.59472779 |
| 22 | NLK | 1.58302669 |
| 23 | FGR | 1.56526245 |
| 24 | ZAK | 1.54884487 |
| 25 | JAK3 | 1.48529723 |
| 26 | PRKD3 | 1.40242966 |
| 27 | BCKDK | 1.38968090 |
| 28 | CCNB1 | 1.38679721 |
| 29 | CDK8 | 1.32930533 |
| 30 | CDC7 | 1.32304347 |
| 31 | RPS6KB2 | 1.28150873 |
| 32 | NUAK1 | 1.22953833 |
| 33 | VRK1 | 1.16562342 |
| 34 | CDK19 | 1.13999234 |
| 35 | WNK4 | 1.00974064 |
| 36 | SGK2 | 0.98972624 |
| 37 | TLK1 | 0.97249159 |
| 38 | ERBB2 | 0.95312901 |
| 39 | MUSK | 0.93121290 |
| 40 | WEE1 | 0.92950940 |
| 41 | DAPK3 | 0.92146089 |
| 42 | BUB1 | 0.91303698 |
| 43 | DYRK3 | 0.89648755 |
| 44 | CAMK2D | 0.89466333 |
| 45 | CDK6 | 0.88644509 |
| 46 | CASK | 0.88147969 |
| 47 | MAP3K5 | 0.87608538 |
| 48 | STK16 | 0.83925216 |
| 49 | MAPK15 | 0.81307368 |
| 50 | MAP3K11 | 0.81306086 |
| 51 | MAP2K7 | 0.80883989 |
| 52 | ADRBK1 | 0.78948704 |
| 53 | CAMK2B | 0.78014024 |
| 54 | SIK2 | 0.77686526 |
| 55 | PLK2 | 0.74883041 |
| 56 | MAP3K4 | 0.72299012 |
| 57 | PDK2 | 0.68934204 |
| 58 | EIF2AK3 | 0.68820752 |
| 59 | EPHA4 | 0.68332851 |
| 60 | FLT3 | 0.68027966 |
| 61 | PBK | 0.67346852 |
| 62 | PLK3 | 0.66477884 |
| 63 | WNK3 | 0.66227146 |
| 64 | FGFR2 | 0.64573937 |
| 65 | TYRO3 | 0.60586846 |
| 66 | PIM1 | 0.59927674 |
| 67 | CSNK1A1 | 0.56893340 |
| 68 | CHEK2 | 0.56084574 |
| 69 | STK11 | 0.53057950 |
| 70 | RPS6KB1 | 0.52599371 |
| 71 | CAMK1 | 0.52013193 |
| 72 | CAMK2G | 0.51856295 |
| 73 | PTK6 | 0.50576086 |
| 74 | PKN1 | 0.50376039 |
| 75 | MAP4K1 | 0.48796199 |
| 76 | JAK2 | 0.48542091 |
| 77 | PIK3CA | 0.45515249 |
| 78 | TTK | 0.45314304 |
| 79 | PHKG2 | 0.42148776 |
| 80 | PHKG1 | 0.42148776 |
| 81 | NEK6 | 0.41947270 |
| 82 | ABL2 | 0.41285551 |
| 83 | CDK5 | 0.40955007 |
| 84 | UHMK1 | 0.40569701 |
| 85 | PKN2 | 0.38414663 |
| 86 | EIF2AK2 | 0.36466077 |
| 87 | SGK1 | 0.36374480 |
| 88 | BRSK2 | 0.35655247 |
| 89 | CSNK1G1 | 0.35125001 |
| 90 | AKT3 | 0.34516186 |
| 91 | AURKA | 0.33019295 |
| 92 | PRKCE | 0.32761462 |
| 93 | TRIM28 | 0.32761223 |
| 94 | MTOR | 0.32191094 |
| 95 | DYRK1A | 0.32065650 |
| 96 | CAMK2A | 0.31969690 |
| 97 | SGK3 | 0.31578105 |
| 98 | FGFR1 | 0.30871338 |
| 99 | ADRBK2 | 0.30242482 |
| 100 | CSNK2A1 | 0.30059730 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | One carbon pool by folate_Homo sapiens_hsa00670 | 3.94072569 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 3.85307213 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.62405244 |
| 4 | Arginine biosynthesis_Homo sapiens_hsa00220 | 3.15775901 |
| 5 | Sulfur relay system_Homo sapiens_hsa04122 | 3.06736754 |
| 6 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 2.96854545 |
| 7 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.53198229 |
| 8 | Parkinsons disease_Homo sapiens_hsa05012 | 2.53047324 |
| 9 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.40503678 |
| 10 | Nicotine addiction_Homo sapiens_hsa05033 | 2.39773683 |
| 11 | Huntingtons disease_Homo sapiens_hsa05016 | 1.91835460 |
| 12 | Alzheimers disease_Homo sapiens_hsa05010 | 1.89980713 |
| 13 | Proteasome_Homo sapiens_hsa03050 | 1.89078200 |
| 14 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.88261897 |
| 15 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.88240244 |
| 16 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.87333495 |
| 17 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.81969398 |
| 18 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.77044960 |
| 19 | GABAergic synapse_Homo sapiens_hsa04727 | 1.74046297 |
| 20 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.72652841 |
| 21 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.72092884 |
| 22 | Morphine addiction_Homo sapiens_hsa05032 | 1.69097960 |
| 23 | Basal transcription factors_Homo sapiens_hsa03022 | 1.68943577 |
| 24 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.67512762 |
| 25 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.63928401 |
| 26 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.53273480 |
| 27 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.42360634 |
| 28 | Galactose metabolism_Homo sapiens_hsa00052 | 1.41700093 |
| 29 | Homologous recombination_Homo sapiens_hsa03440 | 1.41121116 |
| 30 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.36594456 |
| 31 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.35225235 |
| 32 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.32422203 |
| 33 | RNA degradation_Homo sapiens_hsa03018 | 1.25937445 |
| 34 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.18485530 |
| 35 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.16434162 |
| 36 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.15912939 |
| 37 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.14267922 |
| 38 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.14072991 |
| 39 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.09879009 |
| 40 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.08124962 |
| 41 | Taste transduction_Homo sapiens_hsa04742 | 1.03877673 |
| 42 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.02031597 |
| 43 | Olfactory transduction_Homo sapiens_hsa04740 | 1.01167558 |
| 44 | Mismatch repair_Homo sapiens_hsa03430 | 0.97669504 |
| 45 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.96315442 |
| 46 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.93120756 |
| 47 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.88460830 |
| 48 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.85286599 |
| 49 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.84667086 |
| 50 | Retinol metabolism_Homo sapiens_hsa00830 | 0.84298398 |
| 51 | Spliceosome_Homo sapiens_hsa03040 | 0.82811607 |
| 52 | Phototransduction_Homo sapiens_hsa04744 | 0.81074726 |
| 53 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.78238412 |
| 54 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.77067248 |
| 55 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.75279997 |
| 56 | Protein export_Homo sapiens_hsa03060 | 0.74803491 |
| 57 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.74214484 |
| 58 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.73716061 |
| 59 | Circadian entrainment_Homo sapiens_hsa04713 | 0.70999277 |
| 60 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.67792195 |
| 61 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.66259974 |
| 62 | Metabolic pathways_Homo sapiens_hsa01100 | 0.66146814 |
| 63 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.62382937 |
| 64 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.60383750 |
| 65 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.57142512 |
| 66 | RNA polymerase_Homo sapiens_hsa03020 | 0.56257384 |
| 67 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.54118520 |
| 68 | Peroxisome_Homo sapiens_hsa04146 | 0.53280897 |
| 69 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.52022678 |
| 70 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.51809349 |
| 71 | Purine metabolism_Homo sapiens_hsa00230 | 0.51361682 |
| 72 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.50796562 |
| 73 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.48011287 |
| 74 | Mineral absorption_Homo sapiens_hsa04978 | 0.47204427 |
| 75 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.46958312 |
| 76 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.45579659 |
| 77 | RNA transport_Homo sapiens_hsa03013 | 0.44094268 |
| 78 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.43912822 |
| 79 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.43263717 |
| 80 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.42039720 |
| 81 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.41957327 |
| 82 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.41735272 |
| 83 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.39888256 |
| 84 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.39626793 |
| 85 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.36573583 |
| 86 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.35169473 |
| 87 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.33855247 |
| 88 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.31848429 |
| 89 | Cell cycle_Homo sapiens_hsa04110 | 0.29292864 |
| 90 | DNA replication_Homo sapiens_hsa03030 | 0.29028705 |
| 91 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.28632106 |
| 92 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.27078900 |
| 93 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.26108326 |
| 94 | Alcoholism_Homo sapiens_hsa05034 | 0.25665389 |
| 95 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.25067519 |
| 96 | Asthma_Homo sapiens_hsa05310 | 0.24126214 |
| 97 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.21724605 |
| 98 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.19964371 |
| 99 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.19665476 |
| 100 | Axon guidance_Homo sapiens_hsa04360 | 0.16229489 |

