NRBP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein localization to endosome (GO:0036010)4.36073419
2positive regulation of Cdc42 GTPase activity (GO:0043089)3.87209170
3endothelial tube morphogenesis (GO:0061154)3.81708409
4morphogenesis of an endothelium (GO:0003159)3.81708409
5Golgi transport vesicle coating (GO:0048200)3.81060409
6COPI coating of Golgi vesicle (GO:0048205)3.81060409
7antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.71786963
8antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.71786963
9negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.58928783
10regulation of interferon-gamma-mediated signaling pathway (GO:0060334)3.53259031
11regulation of response to interferon-gamma (GO:0060330)3.50747926
12antigen processing and presentation of endogenous antigen (GO:0019883)3.49599845
13peptidyl-proline hydroxylation (GO:0019511)3.45865423
14fusion of sperm to egg plasma membrane (GO:0007342)3.38401614
15stress fiber assembly (GO:0043149)3.26018933
16skin morphogenesis (GO:0043589)3.25083115
17muscle organ morphogenesis (GO:0048644)3.21429600
18glucose 6-phosphate metabolic process (GO:0051156)3.20499678
19COPII vesicle coating (GO:0048208)3.17559861
20sexual reproduction (GO:0019953)3.15904033
21regulation of type I interferon-mediated signaling pathway (GO:0060338)3.15112825
22hyaluronan catabolic process (GO:0030214)3.12284447
23purine nucleobase biosynthetic process (GO:0009113)3.12034025
24NIK/NF-kappaB signaling (GO:0038061)3.11790176
25NADPH regeneration (GO:0006740)3.10950661
26pentose-phosphate shunt (GO:0006098)3.08217095
27membrane protein ectodomain proteolysis (GO:0006509)3.05833150
28positive regulation of extracellular matrix organization (GO:1903055)3.03474605
29chaperone mediated protein folding requiring cofactor (GO:0051085)3.02794410
30membrane protein intracellular domain proteolysis (GO:0031293)3.01967934
31vesicle coating (GO:0006901)2.97853291
32antigen processing and presentation via MHC class Ib (GO:0002475)2.97200662
33nucleobase biosynthetic process (GO:0046112)2.95765356
34protein hydroxylation (GO:0018126)2.95232422
35cell adhesion mediated by integrin (GO:0033627)2.94806057
364-hydroxyproline metabolic process (GO:0019471)2.93972763
37basement membrane organization (GO:0071711)2.90711616
38Arp2/3 complex-mediated actin nucleation (GO:0034314)2.89062029
39regulation of G0 to G1 transition (GO:0070316)2.85705780
40purine-containing compound salvage (GO:0043101)2.82091251
41positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.82037044
42chromosome condensation (GO:0030261)2.81882907
43glycosphingolipid catabolic process (GO:0046479)2.79879226
44epithelial cell-cell adhesion (GO:0090136)2.78352557
45apoptotic cell clearance (GO:0043277)2.77051980
46regulation of translational termination (GO:0006449)2.76388888
47endoplasmic reticulum unfolded protein response (GO:0030968)2.75566504
48cellular copper ion homeostasis (GO:0006878)2.75442827
49antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.71607236
50regulation of cholesterol homeostasis (GO:2000188)2.69644279
51positive regulation of lamellipodium assembly (GO:0010592)2.66635707
52necroptotic process (GO:0070266)2.65672604
53proline biosynthetic process (GO:0006561)2.65499639
54NADH metabolic process (GO:0006734)2.65380880
55formation of translation preinitiation complex (GO:0001731)2.64712514
56negative regulation of protein localization to plasma membrane (GO:1903077)2.64313632
57positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.63558963
58positive regulation of gamma-delta T cell activation (GO:0046645)2.63376781
59adherens junction assembly (GO:0034333)2.63179326
60protein-lipid complex assembly (GO:0065005)2.63141722
61phospholipid scrambling (GO:0017121)2.62544958
62negative regulation of nitric-oxide synthase activity (GO:0051001)2.62446243
63mitotic nuclear envelope disassembly (GO:0007077)2.62065293
64natural killer cell differentiation (GO:0001779)2.61830550
65IMP biosynthetic process (GO:0006188)2.61710795
66regulation of RIG-I signaling pathway (GO:0039535)2.61201074
67endosome to melanosome transport (GO:0035646)2.60686138
68endosome to pigment granule transport (GO:0043485)2.60686138
69embryonic process involved in female pregnancy (GO:0060136)2.60515600
70modulation by symbiont of host cellular process (GO:0044068)2.59563191
71regulation of T-helper 2 cell differentiation (GO:0045628)2.59008677
72regulation of nuclease activity (GO:0032069)2.57767946
73cellular response to unfolded protein (GO:0034620)2.57460131
74barbed-end actin filament capping (GO:0051016)2.57381092
75low-density lipoprotein particle clearance (GO:0034383)2.57208633
76endoplasmic reticulum calcium ion homeostasis (GO:0032469)2.56647988
77positive regulation of lamellipodium organization (GO:1902745)2.56484735
78plasma lipoprotein particle assembly (GO:0034377)2.56009329
79regulation of spindle organization (GO:0090224)2.55438408
80glycolipid catabolic process (GO:0019377)2.54395431
81ER-nucleus signaling pathway (GO:0006984)2.54092463
82purine nucleotide salvage (GO:0032261)2.53185826
83regulation of early endosome to late endosome transport (GO:2000641)2.52193605
84cell-substrate adherens junction assembly (GO:0007045)2.51942704
85focal adhesion assembly (GO:0048041)2.51942704
86peptidyl-arginine omega-N-methylation (GO:0035247)2.51837315
87protein localization to kinetochore (GO:0034501)2.50532138
88nuclear envelope disassembly (GO:0051081)2.50152815
89membrane disassembly (GO:0030397)2.50152815
90regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)2.48576852
91planar cell polarity pathway involved in neural tube closure (GO:0090179)2.48298426
92maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.48148660
93regulation of gamma-delta T cell differentiation (GO:0045586)2.48055680
94glucose catabolic process (GO:0006007)2.47717880
95plasma membrane fusion (GO:0045026)2.46887706
96protein maturation by protein folding (GO:0022417)2.45911210
97positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241)2.45374242
98cellular response to topologically incorrect protein (GO:0035967)2.45291350
99amyloid precursor protein catabolic process (GO:0042987)2.44785319
100negative regulation of cell size (GO:0045792)2.44257219
101very-low-density lipoprotein particle assembly (GO:0034379)2.43561181
102cell-substrate junction assembly (GO:0007044)2.42926510
103glycolytic process (GO:0006096)2.42466402
104regulation of proton transport (GO:0010155)2.42371060
105mRNA cleavage (GO:0006379)2.41650889
106positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.41539339
107positive regulation of protein deacetylation (GO:0090312)2.41451618
108DNA packaging (GO:0006323)2.40000205
109regulation of defense response to virus by virus (GO:0050690)2.39451059
110protein retention in ER lumen (GO:0006621)2.39304687
111positive regulation of natural killer cell differentiation (GO:0032825)2.37439426
112GDP-mannose metabolic process (GO:0019673)2.37325010
113vagina development (GO:0060068)2.36987405
114regulation of tight junction assembly (GO:2000810)2.36868769
115IMP metabolic process (GO:0046040)2.36511771
116regulation of mammary gland epithelial cell proliferation (GO:0033599)2.36409746
117glomerular visceral epithelial cell development (GO:0072015)2.35859876
118positive regulation of protein import into nucleus, translocation (GO:0033160)2.34244833
119mitotic G1 DNA damage checkpoint (GO:0031571)2.34085502
120glucocorticoid receptor signaling pathway (GO:0042921)2.33978801
121regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)2.33686908
122regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.33597564
123regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.33512891
124regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.33017512
125oligosaccharide catabolic process (GO:0009313)2.32939542
126regulation of mitotic spindle organization (GO:0060236)2.32698921
127regulation of interleukin-12 biosynthetic process (GO:0045075)2.32399109
128membrane protein proteolysis (GO:0033619)2.32297769
129regulation of extracellular matrix disassembly (GO:0010715)2.32208892
130negative regulation of T-helper cell differentiation (GO:0045623)2.31943149
131negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.31943149
132tricarboxylic acid cycle (GO:0006099)2.31895154
133nuclear pore organization (GO:0006999)2.31610990
134negative regulation of innate immune response (GO:0045824)2.31199952
135regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.30162603
136substrate-dependent cell migration (GO:0006929)2.28871247
137intracellular estrogen receptor signaling pathway (GO:0030520)2.28255549
138polyamine biosynthetic process (GO:0006596)2.28108902
139mitotic chromosome condensation (GO:0007076)2.27988193
140regulation of necroptotic process (GO:0060544)2.27367901
141galactose catabolic process (GO:0019388)2.27354901
142negative regulation of retinoic acid receptor signaling pathway (GO:0048387)2.25966578
143cellular response to virus (GO:0098586)2.25934083
144oxaloacetate metabolic process (GO:0006107)2.25861284
145peptide catabolic process (GO:0043171)2.25720485
146positive regulation of histone deacetylation (GO:0031065)2.25659655
147positive thymic T cell selection (GO:0045059)2.25300627
148regulation of cytokine secretion involved in immune response (GO:0002739)2.24315659
149activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.24144120
150positive regulation of endothelial cell apoptotic process (GO:2000353)2.23708965
151response to interferon-alpha (GO:0035455)2.22877661
152decidualization (GO:0046697)2.22420866
153positive regulation of nuclease activity (GO:0032075)2.21568848
154response to laminar fluid shear stress (GO:0034616)2.21055689
155regulation of heterotypic cell-cell adhesion (GO:0034114)2.20971424
156ribosome biogenesis (GO:0042254)2.20730409
157regulation of metalloenzyme activity (GO:0048552)2.20450871
158nuclear envelope organization (GO:0006998)2.20196525
159semaphorin-plexin signaling pathway (GO:0071526)2.20083030
160serine transport (GO:0032329)2.18878864
161regulation of B cell receptor signaling pathway (GO:0050855)2.18714849
162fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.18242599
163sperm capacitation (GO:0048240)2.18140761
164cytoskeletal anchoring at plasma membrane (GO:0007016)2.17722982
165positive regulation of heterotypic cell-cell adhesion (GO:0034116)2.17597750
166positive regulation of isotype switching (GO:0045830)2.17406724
167negative regulation of nitric oxide biosynthetic process (GO:0045019)2.17051572
168immunoglobulin mediated immune response (GO:0016064)2.16578497
169purine nucleobase metabolic process (GO:0006144)2.16378270
170nucleotide-sugar biosynthetic process (GO:0009226)2.16314855
171pinocytosis (GO:0006907)2.15553963
172vascular endothelial growth factor signaling pathway (GO:0038084)2.15000392
173regulation of gamma-delta T cell activation (GO:0046643)2.14522211
174cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.14274356
175positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.13579237
176retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.11767222
177JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.10543575
178regulation of translation in response to stress (GO:0043555)2.10191931
179pre-miRNA processing (GO:0031054)2.08938799
180blood vessel maturation (GO:0001955)2.07886233
181regulation of cholesterol storage (GO:0010885)2.07751531
182positive regulation of interferon-alpha production (GO:0032727)2.07221831
183fibroblast migration (GO:0010761)2.07016167
184cardiac myofibril assembly (GO:0055003)2.06663844
185negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.05986106
186maternal placenta development (GO:0001893)2.05844263
187cytokine production involved in immune response (GO:0002367)2.04907965

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human3.58768697
2EGR1_19374776_ChIP-ChIP_THP-1_Human3.39789556
3NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.94866046
4TP63_17297297_ChIP-ChIP_HaCaT_Human2.94494480
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.79638926
6MYC_22102868_ChIP-Seq_BL_Human2.54165754
7FOXM1_23109430_ChIP-Seq_U2OS_Human2.53390286
8LXR_22292898_ChIP-Seq_THP-1_Human2.30611517
9* THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.06739868
10TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.97815540
11IRF8_22096565_ChIP-ChIP_GC-B_Human1.97079903
12ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.94033060
13ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.93115482
14PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.92666744
15CLOCK_20551151_ChIP-Seq_293T_Human1.87607561
16RARG_19884340_ChIP-ChIP_MEFs_Mouse1.87539756
17VDR_21846776_ChIP-Seq_THP-1_Human1.86446304
18MYC_18555785_ChIP-Seq_MESCs_Mouse1.84055515
19ESR2_21235772_ChIP-Seq_MCF-7_Human1.76850091
20ELK3_25401928_ChIP-Seq_HUVEC_Human1.76689843
21IRF8_21731497_ChIP-ChIP_J774_Mouse1.76203730
22STAT6_21828071_ChIP-Seq_BEAS2B_Human1.68658770
23STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.68355734
24TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.68176528
25* MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.67868511
26SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.66136477
27NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.65680816
28SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.64113653
29NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.63248099
30CIITA_25753668_ChIP-Seq_RAJI_Human1.63172865
31MYB_21317192_ChIP-Seq_ERMYB_Mouse1.57017347
32MAF_26560356_Chip-Seq_TH1_Human1.55810969
33ZFP281_18757296_ChIP-ChIP_E14_Mouse1.54663234
34KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.53636340
35* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.52097396
36* TCF7_22412390_ChIP-Seq_EML_Mouse1.50384339
37TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.49151597
38ZNF263_19887448_ChIP-Seq_K562_Human1.47955700
39STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.46306783
40PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.45826392
41* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.44706539
42STAT3_1855785_ChIP-Seq_MESCs_Mouse1.42537081
43GABP_19822575_ChIP-Seq_HepG2_Human1.41713689
44IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.40801241
45FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.40260533
46XRN2_22483619_ChIP-Seq_HELA_Human1.38284308
47CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.36908778
48RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.36452696
49IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.35861361
50P300_27058665_Chip-Seq_ZR-75-30cells_Human1.35666914
51KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.34948570
52PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.34742462
53* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.34655353
54TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.33628080
55UTX_26944678_Chip-Seq_JUKART_Human1.33539495
56NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.33409012
57UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.32821696
58RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.31956670
59* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.31138447
60TP53_22127205_ChIP-Seq_IMR90_Human1.30792036
61MYC_18358816_ChIP-ChIP_MESCs_Mouse1.30491571
62SPI1_23547873_ChIP-Seq_NB4_Human1.30352287
63FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.29552053
64TFEB_21752829_ChIP-Seq_HELA_Human1.29178156
65JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.28632238
66TET1_21451524_ChIP-Seq_MESCs_Mouse1.27190492
67CTCF_27219007_Chip-Seq_ERYTHROID_Human1.26060115
68E2F4_17652178_ChIP-ChIP_JURKAT_Human1.25843675
69CREB1_15753290_ChIP-ChIP_HEK293T_Human1.25770235
70KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.24212267
71MYB_26560356_Chip-Seq_TH2_Human1.23530571
72* ATF3_27146783_Chip-Seq_COLON_Human1.23063274
73KDM2B_26808549_Chip-Seq_DND41_Human1.22927244
74NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.22178809
75HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.21645500
76NOTCH1_21737748_ChIP-Seq_TLL_Human1.21477332
77KLF4_18555785_ChIP-Seq_MESCs_Mouse1.20920010
78* NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.20818131
79TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.20554003
80PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.20090345
81UBF1/2_26484160_Chip-Seq_HMECs_Human1.19897499
82MYC_19030024_ChIP-ChIP_MESCs_Mouse1.19648358
83KDM2B_26808549_Chip-Seq_SUP-B15_Human1.19458473
84P68_20966046_ChIP-Seq_HELA_Human1.19307303
85ELF1_17652178_ChIP-ChIP_JURKAT_Human1.18981299
86ELF1_20517297_ChIP-Seq_JURKAT_Human1.18908092
87E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.18892315
88CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.18122674
89RUNX1_22412390_ChIP-Seq_EML_Mouse1.17828182
90KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.17171577
91KDM2B_26808549_Chip-Seq_K562_Human1.17132648
92BRD4_27068464_Chip-Seq_AML-cells_Mouse1.17086383
93RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.16915752
94ETS1_20019798_ChIP-Seq_JURKAT_Human1.16716828
95KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.16378544
96SMC4_20622854_ChIP-Seq_HELA_Human1.16200428
97GABP_17652178_ChIP-ChIP_JURKAT_Human1.16191668
98HIF1A_21447827_ChIP-Seq_MCF-7_Human1.15728371
99ESR1_21235772_ChIP-Seq_MCF-7_Human1.15652679
100MYC_19079543_ChIP-ChIP_MESCs_Mouse1.14942031
101TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.14694143
102CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.14276189
103POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.12607781
104* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.12403828
105* MYB_26560356_Chip-Seq_TH1_Human1.12314837
106E2F1_18555785_ChIP-Seq_MESCs_Mouse1.11931478
107AR_21909140_ChIP-Seq_LNCAP_Human1.11475081
108TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.10485662
109PPARA_22158963_ChIP-Seq_LIVER_Mouse1.10046746
110TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.09834431
111WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.09595916
112VDR_24763502_ChIP-Seq_THP-1_Human1.08994062
113ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.08855648
114RXR_22158963_ChIP-Seq_LIVER_Mouse1.08600541
115SA1_27219007_Chip-Seq_ERYTHROID_Human1.07755372
116BCOR_27268052_Chip-Seq_Bcells_Human1.06699668
117MAF_26560356_Chip-Seq_TH2_Human1.06157046
118ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.05924880
119NFIB_24661679_ChIP-Seq_LUNG_Mouse1.05876921
120SPI1_23127762_ChIP-Seq_K562_Human1.05799371
121SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.05793117
122* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.05582130
123NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.05284614
124* VDR_23849224_ChIP-Seq_CD4+_Human1.05039073
125DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.04916126
126GATA1_22025678_ChIP-Seq_K562_Human1.04809304
127MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.04763046
128DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.04484947
129HOXB4_20404135_ChIP-ChIP_EML_Mouse1.04248182
130SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.03965626
131SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.03965626
132GATA1_22383799_ChIP-Seq_G1ME_Mouse1.02646910
133KDM5A_27292631_Chip-Seq_BREAST_Human1.02548925
134P63_26484246_Chip-Seq_KERATINOCYTES_Human1.02197606
135SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.02057559
136IRF8_27001747_Chip-Seq_BMDM_Mouse1.01772467
137RACK7_27058665_Chip-Seq_MCF-7_Human1.01738279
138FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.01695443
139STAT4_19710469_ChIP-ChIP_TH1__Mouse1.01621234
140MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.01594073
141E2F1_21310950_ChIP-Seq_MCF-7_Human1.00836352
142RUNX1_27514584_Chip-Seq_MCF-7_Human0.98718148
143NCOR1_26117541_ChIP-Seq_K562_Human0.98430470
144PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.97980354
145BCL6_27268052_Chip-Seq_Bcells_Human0.97269952
146SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.96098327
147CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.95402563
148SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.95340071
149MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.94033750

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005451_abnormal_body_composition3.77758444
2MP0008260_abnormal_autophagy2.87017435
3MP0003705_abnormal_hypodermis_morpholog2.84291750
4MP0005257_abnormal_intraocular_pressure2.80721347
5MP0005410_abnormal_fertilization2.37678523
6MP0004233_abnormal_muscle_weight2.36483152
7MP0008438_abnormal_cutaneous_collagen2.31623698
8MP0003693_abnormal_embryo_hatching2.26488953
9MP0006054_spinal_hemorrhage2.23841773
10MP0002396_abnormal_hematopoietic_system2.16609262
11MP0004272_abnormal_basement_membrane2.13731859
12MP0010352_gastrointestinal_tract_polyps1.99930812
13MP0003950_abnormal_plasma_membrane1.99771338
14MP0001849_ear_inflammation1.99735896
15MP0004084_abnormal_cardiac_muscle1.97378675
16MP0003566_abnormal_cell_adhesion1.94077801
17MP0003279_aneurysm1.91028473
18MP0003172_abnormal_lysosome_physiology1.90494918
19MP0001835_abnormal_antigen_presentation1.89108370
20MP0004808_abnormal_hematopoietic_stem1.86562592
21MP0001545_abnormal_hematopoietic_system1.80199722
22MP0005397_hematopoietic_system_phenotyp1.80199722
23MP0009840_abnormal_foam_cell1.78133176
24MP0004264_abnormal_extraembryonic_tissu1.75398399
25MP0004510_myositis1.74778961
26MP0009278_abnormal_bone_marrow1.73560762
27MP0003329_amyloid_beta_deposits1.70644506
28MP0000685_abnormal_immune_system1.67648831
29MP0003221_abnormal_cardiomyocyte_apopto1.65843615
30MP0008007_abnormal_cellular_replicative1.58732075
31MP0004957_abnormal_blastocyst_morpholog1.58045993
32MP0003077_abnormal_cell_cycle1.56854759
33MP0001853_heart_inflammation1.56201320
34MP0005023_abnormal_wound_healing1.56183472
35MP0003453_abnormal_keratinocyte_physiol1.55283341
36MP0010368_abnormal_lymphatic_system1.51823210
37MP0000604_amyloidosis1.50024209
38MP0001348_abnormal_lacrimal_gland1.44263821
39MP0004858_abnormal_nervous_system1.43558934
40MP0001873_stomach_inflammation1.41640189
41MP0010307_abnormal_tumor_latency1.40224818
42MP0010030_abnormal_orbit_morphology1.38553222
43MP0003111_abnormal_nucleus_morphology1.36759892
44MP0002877_abnormal_melanocyte_morpholog1.36579183
45MP0003123_paternal_imprinting1.36491971
46MP0000003_abnormal_adipose_tissue1.35274180
47MP0002254_reproductive_system_inflammat1.33682714
48MP0003436_decreased_susceptibility_to1.33654889
49MP0005503_abnormal_tendon_morphology1.33122551
50MP0000343_altered_response_to1.33070213
51MP0002796_impaired_skin_barrier1.29415207
52MP0005275_abnormal_skin_tensile1.29155970
53MP0005076_abnormal_cell_differentiation1.27203065
54MP0003941_abnormal_skin_development1.27172008
55MP0009785_altered_susceptibility_to1.26929225
56MP0003763_abnormal_thymus_physiology1.22866350
57MP0010630_abnormal_cardiac_muscle1.21953283
58MP0002398_abnormal_bone_marrow1.20867268
59MP0004947_skin_inflammation1.19943489
60MP0003646_muscle_fatigue1.19741634
61MP0003300_gastrointestinal_ulcer1.18242490
62MP0000767_abnormal_smooth_muscle1.18041727
63MP0001800_abnormal_humoral_immune1.16831707
64MP0002332_abnormal_exercise_endurance1.15798454
65MP0002452_abnormal_antigen_presenting1.14689198
66MP0001730_embryonic_growth_arrest1.13272543
67MP0009384_cardiac_valve_regurgitation1.13112992
68MP0003191_abnormal_cellular_cholesterol1.12083567
69MP0001533_abnormal_skeleton_physiology1.11699814
70MP0000858_altered_metastatic_potential1.11519928
71MP0000733_abnormal_muscle_development1.11419046
72MP0002060_abnormal_skin_morphology1.11102804
73MP0009333_abnormal_splenocyte_physiolog1.11047127
74MP0003303_peritoneal_inflammation1.10771601
75MP0002998_abnormal_bone_remodeling1.10768171
76MP0001915_intracranial_hemorrhage1.08895955
77MP0005464_abnormal_platelet_physiology1.08468550
78MP0008004_abnormal_stomach_pH1.07598080
79MP0004087_abnormal_muscle_fiber1.06416199
80MP0000689_abnormal_spleen_morphology1.05107448
81MP0003828_pulmonary_edema1.04680417
82MP0010155_abnormal_intestine_physiology1.04633559
83MP0002722_abnormal_immune_system1.04285827
84MP0001819_abnormal_immune_cell1.04028473
85MP0002405_respiratory_system_inflammati1.03880389
86MP0003984_embryonic_growth_retardation1.03878834
87MP0006138_congestive_heart_failure1.03768763
88MP0002269_muscular_atrophy1.03366114
89MP0002420_abnormal_adaptive_immunity1.03264334
90MP0002088_abnormal_embryonic_growth/wei1.02747814
91MP0003448_altered_tumor_morphology1.02194318
92MP0005501_abnormal_skin_physiology1.01888880
93MP0005387_immune_system_phenotype1.01849909
94MP0001790_abnormal_immune_system1.01849909
95MP0000750_abnormal_muscle_regeneration1.01390600
96MP0005385_cardiovascular_system_phenoty1.01176102
97MP0001544_abnormal_cardiovascular_syste1.01176102
98MP0000350_abnormal_cell_proliferation0.99681198
99MP0005058_abnormal_lysosome_morphology0.99283614
100MP0002419_abnormal_innate_immunity0.98936861
101MP0005671_abnormal_response_to0.97833056
102MP0002138_abnormal_hepatobiliary_system0.97532373
103MP0002723_abnormal_immune_serum0.97476148
104MP0005330_cardiomyopathy0.97100383
105MP0002429_abnormal_blood_cell0.96126349
106MP0002896_abnormal_bone_mineralization0.95455607
107MP0005025_abnormal_response_to0.94597866
108MP0000716_abnormal_immune_system0.94273834
109MP0005310_abnormal_salivary_gland0.93700971
110MP0005000_abnormal_immune_tolerance0.92926485
111MP0002086_abnormal_extraembryonic_tissu0.92827943
112MP0001243_abnormal_dermal_layer0.92632170
113MP0003091_abnormal_cell_migration0.92338753
114MP0001958_emphysema0.92108849
115MP0003075_altered_response_to0.92034821
116MP0005380_embryogenesis_phenotype0.92015602
117MP0001672_abnormal_embryogenesis/_devel0.92015602
118MP0005375_adipose_tissue_phenotype0.91778788
119MP0000490_abnormal_crypts_of0.91061068
120MP0010094_abnormal_chromosome_stability0.90347829
121MP0001845_abnormal_inflammatory_respons0.90226580
122MP0000703_abnormal_thymus_morphology0.90018884
123MP0005623_abnormal_meninges_morphology0.89656943
124MP0002019_abnormal_tumor_incidence0.88526021
125MP0000747_muscle_weakness0.88325079
126MP0001697_abnormal_embryo_size0.88054797
127MP0002080_prenatal_lethality0.88025353
128MP0000751_myopathy0.87622457
129MP0001879_abnormal_lymphatic_vessel0.87256848
130MP0006082_CNS_inflammation0.87036887
131MP0002166_altered_tumor_susceptibility0.86214589
132MP0001216_abnormal_epidermal_layer0.86201281
133MP0004036_abnormal_muscle_relaxation0.85362639
134MP0005621_abnormal_cell_physiology0.84230048
135MP0000759_abnormal_skeletal_muscle0.82845183
136MP0002089_abnormal_postnatal_growth/wei0.82303278
137MP0001542_abnormal_bone_strength0.82111324
138MP0005165_increased_susceptibility_to0.82083322
139MP0005670_abnormal_white_adipose0.79786652
140MP0005390_skeleton_phenotype0.79382771
141MP0005409_darkened_coat_color0.78995549
142MP0000467_abnormal_esophagus_morphology0.77502763
143MP0005377_hearing/vestibular/ear_phenot0.77246256
144MP0003878_abnormal_ear_physiology0.77246256
145MP0005164_abnormal_response_to0.76851488
146MP0002139_abnormal_hepatobiliary_system0.74547314
147MP0000678_abnormal_parathyroid_gland0.72315670
148MP0002148_abnormal_hypersensitivity_rea0.72303629
149MP0003795_abnormal_bone_structure0.69251000
150MP0001614_abnormal_blood_vessel0.68990005
151MP0000534_abnormal_ureter_morphology0.66850112
152MP0003656_abnormal_erythrocyte_physiolo0.65908802
153MP0000249_abnormal_blood_vessel0.65802446
154MP0000749_muscle_degeneration0.65452274

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)4.15266472
2Abnormality of the nasal mucosa (HP:0000433)3.91358525
3Nasal polyposis (HP:0100582)3.65123159
4Cerebral aneurysm (HP:0004944)3.35781317
5Ankle contracture (HP:0006466)3.27671372
6Aortic aneurysm (HP:0004942)3.24562121
7Vertebral compression fractures (HP:0002953)3.21391738
8Abnormality of liposaccharide metabolism (HP:0010968)3.07942367
9Abnormality of glycosphingolipid metabolism (HP:0004343)3.07942367
10Abnormality of glycolipid metabolism (HP:0010969)3.07942367
11Distal lower limb muscle weakness (HP:0009053)3.05065615
12Deep venous thrombosis (HP:0002625)2.76334190
13Distal lower limb amyotrophy (HP:0008944)2.71680558
14Increased connective tissue (HP:0009025)2.69853622
15Atrioventricular block (HP:0001678)2.66064613
16Myocardial infarction (HP:0001658)2.65228141
17Progressive muscle weakness (HP:0003323)2.64606189
18Autoimmune thrombocytopenia (HP:0001973)2.64390805
19Dysostosis multiplex (HP:0000943)2.61525102
20Premature rupture of membranes (HP:0001788)2.59728493
21Cholecystitis (HP:0001082)2.58388670
22Abnormal gallbladder physiology (HP:0012438)2.58388670
23Ragged-red muscle fibers (HP:0003200)2.54796968
24Vacuolated lymphocytes (HP:0001922)2.54267406
25Aortic dissection (HP:0002647)2.53544737
26Striae distensae (HP:0001065)2.52930758
27Selective tooth agenesis (HP:0001592)2.50294889
28Spinal rigidity (HP:0003306)2.50209450
29Thin bony cortex (HP:0002753)2.48673598
30Osteolytic defects of the phalanges of the hand (HP:0009771)2.46221694
31Osteolytic defects of the hand bones (HP:0009699)2.46221694
32Asymmetry of the thorax (HP:0001555)2.45646347
33Mesangial abnormality (HP:0001966)2.42115571
34Biconcave vertebral bodies (HP:0004586)2.38877996
35Loss of speech (HP:0002371)2.37421366
36Degeneration of anterior horn cells (HP:0002398)2.35654478
37Abnormality of the anterior horn cell (HP:0006802)2.35654478
38Hematochezia (HP:0002573)2.35418158
39Asymmetric septal hypertrophy (HP:0001670)2.34115497
40Atrophic scars (HP:0001075)2.33197410
41Polycythemia (HP:0001901)2.29982264
42Urinary glycosaminoglycan excretion (HP:0003541)2.28836305
43Mucopolysacchariduria (HP:0008155)2.28836305
44Difficulty climbing stairs (HP:0003551)2.26371996
45Pustule (HP:0200039)2.25862029
46Dilatation of the ascending aorta (HP:0005111)2.24072312
47Abnormality of mucopolysaccharide metabolism (HP:0011020)2.23423147
48Abnormality of polysaccharide metabolism (HP:0011012)2.23423147
49Abnormality of glycosaminoglycan metabolism (HP:0004371)2.23423147
50Aneurysm (HP:0002617)2.22743032
51Cervical subluxation (HP:0003308)2.19600629
52Myoglobinuria (HP:0002913)2.15674314
53Abnormality of the acetabulum (HP:0003170)2.12327334
54Nonimmune hydrops fetalis (HP:0001790)2.11854028
55Fatigue (HP:0012378)2.11697144
56J-shaped sella turcica (HP:0002680)2.11133716
57Type 1 muscle fiber predominance (HP:0003803)2.09621617
58Recurrent abscess formation (HP:0002722)2.08208892
59Abnormality of macrophages (HP:0004311)2.08111091
60Arterial tortuosity (HP:0005116)2.07324093
61Achilles tendon contracture (HP:0001771)2.07219658
62Natal tooth (HP:0000695)2.05704168
63Nuclear cataract (HP:0100018)2.04833774
64Flat acetabular roof (HP:0003180)2.03886746
65Back pain (HP:0003418)2.03320436
66Facial diplegia (HP:0001349)2.02927511
67Vascular tortuosity (HP:0004948)2.02841769
68Esophageal varix (HP:0002040)2.02755910
69Hyperacusis (HP:0010780)2.02291037
70Long palpebral fissure (HP:0000637)2.00920884
71Abnormal ossification of hand bones (HP:0005921)2.00276658
72Bicuspid aortic valve (HP:0001647)1.99856505
73Abnormality of carpal bone ossification (HP:0006257)1.98580510
74Multiple enchondromatosis (HP:0005701)1.98410229
75Hand muscle atrophy (HP:0009130)1.96941134
76Subacute progressive viral hepatitis (HP:0006572)1.96677235
77Abnormality of the Achilles tendon (HP:0005109)1.96367433
78Abnormality of the calcaneus (HP:0008364)1.95867348
79Muscle fibrillation (HP:0010546)1.95080685
80Muscle fiber splitting (HP:0003555)1.94580822
81Wormian bones (HP:0002645)1.94088962
82Bundle branch block (HP:0011710)1.93923205
83Recurrent bacterial skin infections (HP:0005406)1.92253897
84Blue sclerae (HP:0000592)1.91558793
85Amyloidosis (HP:0011034)1.91553274
86Eczematoid dermatitis (HP:0000976)1.90995249
87Ventricular tachycardia (HP:0004756)1.88894419
88Frequent falls (HP:0002359)1.88663664
89Axonal loss (HP:0003447)1.88321568
90Lower limb amyotrophy (HP:0007210)1.87865458
91Shallow orbits (HP:0000586)1.87168878
92Thrombocytosis (HP:0001894)1.86760709
93Hemorrhage of the eye (HP:0011885)1.84388242
94Reduced subcutaneous adipose tissue (HP:0003758)1.83443529
95Wrist flexion contracture (HP:0001239)1.83442667
96Hypoalphalipoproteinemia (HP:0003233)1.83204468
97Limb-girdle muscle atrophy (HP:0003797)1.83095135
98Centrally nucleated skeletal muscle fibers (HP:0003687)1.82593711
99Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.82267237
100High pitched voice (HP:0001620)1.81239843
101Bladder diverticulum (HP:0000015)1.80680145
102Cerebral inclusion bodies (HP:0100314)1.80380042
103Prolonged neonatal jaundice (HP:0006579)1.79875335
104Lipoatrophy (HP:0100578)1.79658156
105Cellulitis (HP:0100658)1.79439176
106Abnormal atrioventricular conduction (HP:0005150)1.79286564
107Mitral valve prolapse (HP:0001634)1.78877722
108Enlarged penis (HP:0000040)1.78509855
109Spondylolisthesis (HP:0003302)1.77400836
110Peritonitis (HP:0002586)1.77202031
111Heart block (HP:0012722)1.75611189
112Spontaneous hematomas (HP:0007420)1.75381911
113Broad metatarsal (HP:0001783)1.74529014
114Long toe (HP:0010511)1.74039002
115Exercise-induced muscle cramps (HP:0003710)1.73584479
116Short nail (HP:0001799)1.72206618
117Rhabdomyolysis (HP:0003201)1.71608170
118Ulnar deviation of the wrist (HP:0003049)1.71585944
119Abnormality of the fingertips (HP:0001211)1.71347023
120Abnormality of the umbilical cord (HP:0010881)1.71028062
121Apathy (HP:0000741)1.70432246
122Abnormality of dentin (HP:0010299)1.70344180
123Pelvic girdle muscle weakness (HP:0003749)1.69855022
124Slender long bone (HP:0003100)1.69683305
125Increased density of long bones (HP:0006392)1.69498588
126Neurofibrillary tangles (HP:0002185)1.69164529
127Soft skin (HP:0000977)1.68658636
128Advanced eruption of teeth (HP:0006288)1.67450171
129Systemic lupus erythematosus (HP:0002725)1.66939034
130Periodontitis (HP:0000704)1.65760374
131Calcaneovalgus deformity (HP:0001848)1.65420086
132Broad face (HP:0000283)1.65311471
133Genu recurvatum (HP:0002816)1.65242446
134Mitral stenosis (HP:0001718)1.65188479
135Syringomyelia (HP:0003396)1.65165602
136Abnormality of the distal phalanges of the toes (HP:0010182)1.64891934
137Neoplasm of head and neck (HP:0012288)1.64799652
138Esophageal neoplasm (HP:0100751)1.64799652
139Deformed sella turcica (HP:0002681)1.64194044
140Camptodactyly of toe (HP:0001836)1.64006650
141Hypercholesterolemia (HP:0003124)1.63244176
142Interstitial pulmonary disease (HP:0006530)1.62569830
143Termporal pattern (HP:0011008)1.62478920
144Insidious onset (HP:0003587)1.62478920
145Spinal muscular atrophy (HP:0007269)1.62396517
146Progressive sensorineural hearing impairment (HP:0000408)1.62355644
147Short 4th metacarpal (HP:0010044)1.62346522
148Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.62346522
149Diminished motivation (HP:0000745)1.62241345
150Right ventricular cardiomyopathy (HP:0011663)1.62057171
151IgM deficiency (HP:0002850)1.61795174
152Abnormal delivery (HP:0001787)1.61008219
153Flattened epiphyses (HP:0003071)1.60928463
154Tongue fasciculations (HP:0001308)1.60364163
155Myositis (HP:0100614)1.60246572
156Mildly elevated creatine phosphokinase (HP:0008180)1.59652306
157Insomnia (HP:0100785)1.58713001
158Distal upper limb amyotrophy (HP:0007149)1.58320828
159Upper limb amyotrophy (HP:0009129)1.58320828
160Abnormality of the motor neurons (HP:0002450)1.58267030
161Abnormal neuron morphology (HP:0012757)1.58267030
162Increased cerebral lipofuscin (HP:0011813)1.58203399
163Lymphangioma (HP:0100764)1.57660804
164Ulnar bowing (HP:0003031)1.57375011
165Spinal cord lesions (HP:0100561)1.56203714
166Trismus (HP:0000211)1.55065830
167Bone pain (HP:0002653)1.54928596
168Hyperparathyroidism (HP:0000843)1.54410811
169Cholelithiasis (HP:0001081)1.53332658
170Ovoid vertebral bodies (HP:0003300)1.53283211

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB33.76799665
2DDR22.90986992
3IRAK32.78868367
4ERN12.78066586
5PKN22.59438402
6TTN2.37380292
7RIPK12.18431169
8RPS6KA42.16567724
9MAP4K12.13511942
10SMG12.01320876
11STK101.94286690
12KDR1.92519607
13MAP2K31.91237406
14NEK11.91005254
15ICK1.89602515
16EIF2AK11.89462225
17TGFBR21.89428897
18PRPF4B1.85656517
19BUB11.84569050
20PAK41.73043385
21MAP3K101.68154421
22TBK11.64531261
23EPHA21.63683595
24TYK21.63200720
25ACVR1B1.61167860
26NEK21.58512294
27FLT31.57063728
28STK31.54057515
29NEK91.53062025
30MYLK1.52905094
31PTK61.47819838
32FGFR41.47795139
33ZAP701.46229456
34LRRK21.40841827
35EEF2K1.36959390
36JAK31.36199280
37NTRK11.35973711
38LIMK11.28882761
39STK241.28054124
40TGFBR11.27431974
41DMPK1.23785654
42MOS1.21144974
43LATS21.19498730
44CHUK1.19412697
45MAP3K111.15775405
46PLK41.14991120
47ARAF1.13866592
48JAK11.12473606
49TAOK11.11827136
50EPHB11.08772391
51PDGFRA1.07340678
52STK381.06774144
53PIM21.05343942
54DYRK1B1.02603113
55KIT1.01968019
56CDK41.01001775
57MAP3K141.00578381
58PDPK10.94591237
59TSSK60.94465883
60FGFR30.94171437
61BMX0.93802829
62BRSK20.92893034
63TESK10.92478331
64SIK10.92417727
65LMTK20.90060265
66BLK0.88040184
67RPS6KA20.87999693
68CDK70.87037840
69ALK0.86439924
70BTK0.85499167
71CDC42BPA0.85273300
72KSR20.84132054
73CSF1R0.82243173
74MAP3K80.81259078
75MAP3K120.80812893
76PIM10.79722508
77TIE10.77917551
78TESK20.77228289
79MAP3K30.77122394
80ERBB40.76453955
81PDK30.74870265
82PDK40.74870265
83MST1R0.73689631
84ITK0.72815724
85MAP3K10.70864105
86MAP3K50.70562457
87SCYL20.70307181
88TYRO30.69784991
89SIK30.67596967
90IKBKE0.67371779
91MET0.66793315
92FGR0.66692389
93PRKG20.66242509
94NEK60.65107217
95PTK20.64528334
96PAK20.63602445
97RET0.63144441
98TEC0.62656530
99MARK30.62526922
100MTOR0.62302413
101ILK0.61893248
102BCKDK0.59691003
103CDC70.59339700
104CDK90.59086007
105MAPK110.59078544
106CDK60.58113106
107CDK120.57583100
108MAPKAPK30.57388532
109TAOK20.56700760
110WEE10.56484263
111MUSK0.55146091
112PRKD20.54625203
113ROCK20.53884445
114PBK0.53734261
115BRD40.53683154
116MAP2K20.53394248
117CCNB10.53187074
118GRK60.52918162
119GRK70.52439137
120IKBKB0.49061289
121PDK10.48903396
122PLK10.48681615
123SGK30.48299303
124DYRK30.47459431
125AURKB0.46865227
126FGFR10.45944800
127BRSK10.45255565
128TXK0.44722418
129RAF10.44283575
130ATR0.43307554
131PDGFRB0.42941996
132LATS10.42598823
133DAPK30.41720923
134NME20.40822040
135DAPK10.40821896
136STK40.40802488
137EPHA30.40714471
138CSK0.40674382
139ABL20.40648264
140JAK20.40529891
141MAPKAPK20.40083777
142MAP2K60.39845557
143MATK0.39661124
144ROCK10.39223458
145PAK10.38265603
146RPS6KL10.35267033
147RPS6KC10.35267033

Predicted pathways (KEGG)

RankGene SetZ-score
1Butirosin and neomycin biosynthesis_Homo sapiens_hsa005243.22298041
2Other glycan degradation_Homo sapiens_hsa005113.13574400
3Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.60532481
4Glycosaminoglycan degradation_Homo sapiens_hsa005312.50897363
52-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.15478941
6DNA replication_Homo sapiens_hsa030301.86520884
7Leishmaniasis_Homo sapiens_hsa051401.84466987
8Cell cycle_Homo sapiens_hsa041101.81400746
9Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.63532079
10Antigen processing and presentation_Homo sapiens_hsa046121.59418771
11RNA transport_Homo sapiens_hsa030131.56504256
12Base excision repair_Homo sapiens_hsa034101.55444822
13Legionellosis_Homo sapiens_hsa051341.52348378
14Measles_Homo sapiens_hsa051621.50407180
15Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.48382470
16Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.44665212
17Vibrio cholerae infection_Homo sapiens_hsa051101.44176202
18Viral myocarditis_Homo sapiens_hsa054161.40308432
19Toxoplasmosis_Homo sapiens_hsa051451.37163143
20Herpes simplex infection_Homo sapiens_hsa051681.35764088
21Chronic myeloid leukemia_Homo sapiens_hsa052201.34530098
22Epstein-Barr virus infection_Homo sapiens_hsa051691.33255835
23Shigellosis_Homo sapiens_hsa051311.23873084
24p53 signaling pathway_Homo sapiens_hsa041151.23824714
25Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.23778637
26Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.23717926
27Small cell lung cancer_Homo sapiens_hsa052221.22930085
28Apoptosis_Homo sapiens_hsa042101.21874205
29Osteoclast differentiation_Homo sapiens_hsa043801.21594711
30Intestinal immune network for IgA production_Homo sapiens_hsa046721.19437727
31Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.18716437
32Influenza A_Homo sapiens_hsa051641.18328893
33Acute myeloid leukemia_Homo sapiens_hsa052211.14788985
34Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.12471540
35B cell receptor signaling pathway_Homo sapiens_hsa046621.11530706
36Leukocyte transendothelial migration_Homo sapiens_hsa046701.08616266
37Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.07761684
38HTLV-I infection_Homo sapiens_hsa051661.07486807
39Mismatch repair_Homo sapiens_hsa034301.06735508
40Toll-like receptor signaling pathway_Homo sapiens_hsa046201.06005454
41Pancreatic cancer_Homo sapiens_hsa052121.05327572
42TNF signaling pathway_Homo sapiens_hsa046681.05124695
43Proteasome_Homo sapiens_hsa030501.04938349
44Insulin signaling pathway_Homo sapiens_hsa049101.04704189
45Biosynthesis of amino acids_Homo sapiens_hsa012301.04699478
46Carbon metabolism_Homo sapiens_hsa012001.04270065
47Jak-STAT signaling pathway_Homo sapiens_hsa046301.04120254
48Insulin resistance_Homo sapiens_hsa049311.01343266
49RNA polymerase_Homo sapiens_hsa030201.01075308
50Spliceosome_Homo sapiens_hsa030401.00445106
51Viral carcinogenesis_Homo sapiens_hsa052031.00247488
52RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.99599830
53AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.99462671
54Notch signaling pathway_Homo sapiens_hsa043300.98944713
55NF-kappa B signaling pathway_Homo sapiens_hsa040640.97307834
56Hepatitis B_Homo sapiens_hsa051610.95320180
57N-Glycan biosynthesis_Homo sapiens_hsa005100.94186330
58Pentose phosphate pathway_Homo sapiens_hsa000300.91842534
59Focal adhesion_Homo sapiens_hsa045100.91279265
60Staphylococcus aureus infection_Homo sapiens_hsa051500.91139829
61Galactose metabolism_Homo sapiens_hsa000520.90941431
62Neurotrophin signaling pathway_Homo sapiens_hsa047220.90917953
63Proteoglycans in cancer_Homo sapiens_hsa052050.90630474
64Prolactin signaling pathway_Homo sapiens_hsa049170.90271375
65Prion diseases_Homo sapiens_hsa050200.90023957
66Primary immunodeficiency_Homo sapiens_hsa053400.88983008
67Central carbon metabolism in cancer_Homo sapiens_hsa052300.88316833
68Caffeine metabolism_Homo sapiens_hsa002320.87938587
69Adherens junction_Homo sapiens_hsa045200.87540100
70mTOR signaling pathway_Homo sapiens_hsa041500.87530416
71HIF-1 signaling pathway_Homo sapiens_hsa040660.86735559
72Colorectal cancer_Homo sapiens_hsa052100.85876496
73Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.83926865
74Regulation of actin cytoskeleton_Homo sapiens_hsa048100.82903472
75Malaria_Homo sapiens_hsa051440.82481391
76Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.81668543
77Thyroid cancer_Homo sapiens_hsa052160.81125078
78Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.79781701
79Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.79629656
80ECM-receptor interaction_Homo sapiens_hsa045120.79552100
81Complement and coagulation cascades_Homo sapiens_hsa046100.78960803
82Phagosome_Homo sapiens_hsa041450.78729665
83Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.78638058
84Endometrial cancer_Homo sapiens_hsa052130.77708766
85Sphingolipid metabolism_Homo sapiens_hsa006000.76930500
86Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.76000699
87Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.75910447
88Steroid biosynthesis_Homo sapiens_hsa001000.75788205
89Lysosome_Homo sapiens_hsa041420.74895384
90Pyrimidine metabolism_Homo sapiens_hsa002400.74826044
91Selenocompound metabolism_Homo sapiens_hsa004500.74587766
92Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.73065722
93Prostate cancer_Homo sapiens_hsa052150.72452887
94Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.70099179
95Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.69798189
96Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.68955859
97Platelet activation_Homo sapiens_hsa046110.68186112
98T cell receptor signaling pathway_Homo sapiens_hsa046600.68100592
99Fatty acid biosynthesis_Homo sapiens_hsa000610.67994041
100FoxO signaling pathway_Homo sapiens_hsa040680.67436883
101Tuberculosis_Homo sapiens_hsa051520.66948520
102Thyroid hormone signaling pathway_Homo sapiens_hsa049190.66865816
103Non-small cell lung cancer_Homo sapiens_hsa052230.66020731
104Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.65752771
105Adipocytokine signaling pathway_Homo sapiens_hsa049200.65385262
106Sphingolipid signaling pathway_Homo sapiens_hsa040710.63890053
107MicroRNAs in cancer_Homo sapiens_hsa052060.62686050
108VEGF signaling pathway_Homo sapiens_hsa043700.61297330
109Salmonella infection_Homo sapiens_hsa051320.59790626
110Fatty acid degradation_Homo sapiens_hsa000710.59424976
111Renal cell carcinoma_Homo sapiens_hsa052110.59419604
112mRNA surveillance pathway_Homo sapiens_hsa030150.59386754
113Fructose and mannose metabolism_Homo sapiens_hsa000510.59344745
114PPAR signaling pathway_Homo sapiens_hsa033200.59321177
115Allograft rejection_Homo sapiens_hsa053300.59249693
116Pertussis_Homo sapiens_hsa051330.58388380
117ErbB signaling pathway_Homo sapiens_hsa040120.57708327
118Glioma_Homo sapiens_hsa052140.56797701
119Endocytosis_Homo sapiens_hsa041440.56674473
120AMPK signaling pathway_Homo sapiens_hsa041520.56112054
121Hepatitis C_Homo sapiens_hsa051600.55980603
122Amoebiasis_Homo sapiens_hsa051460.55650312
123Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.54880798
124Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.54242392
125Bladder cancer_Homo sapiens_hsa052190.53939907
126Estrogen signaling pathway_Homo sapiens_hsa049150.49214377
127Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.47683418
128Longevity regulating pathway - mammal_Homo sapiens_hsa042110.47071344
129Chemokine signaling pathway_Homo sapiens_hsa040620.46388873
130Inositol phosphate metabolism_Homo sapiens_hsa005620.45262445
131Tight junction_Homo sapiens_hsa045300.44809705
132Cyanoamino acid metabolism_Homo sapiens_hsa004600.43826810

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