NRIP2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuron cell-cell adhesion (GO:0007158)5.83138791
2dopamine transport (GO:0015872)5.30722682
3dopamine biosynthetic process (GO:0042416)4.85797492
4vocalization behavior (GO:0071625)4.79805152
5synaptic vesicle exocytosis (GO:0016079)4.62672710
6synaptic vesicle docking involved in exocytosis (GO:0016081)4.59841901
7negative regulation of neurotransmitter transport (GO:0051589)4.39093484
8regulation of dopamine metabolic process (GO:0042053)4.21258755
9regulation of catecholamine metabolic process (GO:0042069)4.21258755
10neurotransmitter catabolic process (GO:0042135)4.14524244
11regulation of short-term neuronal synaptic plasticity (GO:0048172)4.03679437
12catecholamine transport (GO:0051937)4.01602456
13ionotropic glutamate receptor signaling pathway (GO:0035235)3.80320050
14presynaptic membrane organization (GO:0097090)3.78968900
15membrane depolarization during action potential (GO:0086010)3.78520287
16neuronal action potential propagation (GO:0019227)3.78019575
17presynaptic membrane assembly (GO:0097105)3.77778069
18response to cocaine (GO:0042220)3.76336003
19long-chain fatty acid biosynthetic process (GO:0042759)3.76121746
20regulation of synaptic vesicle exocytosis (GO:2000300)3.73549471
21glutamate secretion (GO:0014047)3.71236586
22neuron-neuron synaptic transmission (GO:0007270)3.71216748
23protein localization to synapse (GO:0035418)3.71167391
24positive regulation of synapse maturation (GO:0090129)3.70522403
25gamma-aminobutyric acid signaling pathway (GO:0007214)3.68882953
26negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.65206666
27regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.65039834
28L-amino acid import (GO:0043092)3.63754401
29phenol-containing compound catabolic process (GO:0019336)3.62077577
30positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.62028217
31neurotransmitter secretion (GO:0007269)3.60678946
32regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.57562960
33neuron recognition (GO:0008038)3.57551839
34regulation of synapse maturation (GO:0090128)3.57158115
35regulation of dopamine secretion (GO:0014059)3.55941355
36neurotransmitter biosynthetic process (GO:0042136)3.52302920
37central nervous system myelination (GO:0022010)3.50521780
38axon ensheathment in central nervous system (GO:0032291)3.50521780
39mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.49828597
40neurotransmitter transport (GO:0006836)3.48533521
41synaptic transmission, glutamatergic (GO:0035249)3.47869863
42negative regulation of cytosolic calcium ion concentration (GO:0051481)3.47627743
43proline transport (GO:0015824)3.47395921
44glutamate receptor signaling pathway (GO:0007215)3.43462013
45regulation of vesicle fusion (GO:0031338)3.40938426
46positive regulation of synapse assembly (GO:0051965)3.37505148
47serotonin receptor signaling pathway (GO:0007210)3.37057601
48locomotory exploration behavior (GO:0035641)3.34902630
49regulation of excitatory postsynaptic membrane potential (GO:0060079)3.32532354
50regulation of neurotransmitter levels (GO:0001505)3.32427192
51synaptic transmission, dopaminergic (GO:0001963)3.31665788
52negative regulation of cAMP-mediated signaling (GO:0043951)3.27372614
53behavioral response to cocaine (GO:0048148)3.27008241
54regulation of synaptic vesicle transport (GO:1902803)3.26801228
55transferrin transport (GO:0033572)3.24822749
56negative regulation of synaptic transmission, GABAergic (GO:0032229)3.24784724
57dendritic spine morphogenesis (GO:0060997)3.23808836
58regulation of glutamate receptor signaling pathway (GO:1900449)3.21847807
59positive regulation of neurotransmitter transport (GO:0051590)3.21064452
60detection of calcium ion (GO:0005513)3.17480412
61neurotransmitter uptake (GO:0001504)3.15551865
62postsynaptic membrane organization (GO:0001941)3.14310008
63ATP hydrolysis coupled proton transport (GO:0015991)3.13989299
64energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.13989299
65ferric iron transport (GO:0015682)3.13245623
66trivalent inorganic cation transport (GO:0072512)3.13245623
67mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.12961010
68transmission of nerve impulse (GO:0019226)3.12171617
69membrane depolarization (GO:0051899)3.09782662
70neurotransmitter-gated ion channel clustering (GO:0072578)3.09626141
71microtubule nucleation (GO:0007020)3.08520543
72mating behavior (GO:0007617)3.08046056
73adult walking behavior (GO:0007628)3.07567125
74regulation of postsynaptic membrane potential (GO:0060078)3.07457581
75auditory behavior (GO:0031223)3.07250917
76positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.06794593
77response to insecticide (GO:0017085)3.04478819
78neuronal ion channel clustering (GO:0045161)3.03996587
79neuromuscular process controlling posture (GO:0050884)3.01865785
80startle response (GO:0001964)3.01214611
81positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.01057513
82cellular potassium ion homeostasis (GO:0030007)3.00961875
83detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.99642924
84gamma-aminobutyric acid transport (GO:0015812)2.98735693
85regulation of dopamine uptake involved in synaptic transmission (GO:0051584)2.98337203
86regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)2.98337203
87cyclic nucleotide catabolic process (GO:0009214)2.96685417
88synaptic vesicle maturation (GO:0016188)2.95408902
89axonal fasciculation (GO:0007413)2.95304932
90catecholamine biosynthetic process (GO:0042423)2.95008515
91catechol-containing compound biosynthetic process (GO:0009713)2.95008515
92potassium ion import (GO:0010107)2.94917859
93sodium ion export (GO:0071436)2.94454110
94cAMP catabolic process (GO:0006198)2.94436730
95dopamine metabolic process (GO:0042417)2.93719727
96regulation of neurotransmitter transport (GO:0051588)2.93452901
97response to histamine (GO:0034776)2.93277833
98energy coupled proton transport, down electrochemical gradient (GO:0015985)2.92814423
99ATP synthesis coupled proton transport (GO:0015986)2.92814423
100synapse assembly (GO:0007416)2.91158171
101synaptic vesicle endocytosis (GO:0048488)2.91005493
102C4-dicarboxylate transport (GO:0015740)2.90891923
103mechanosensory behavior (GO:0007638)2.90866582
104regulation of synaptic transmission, glutamatergic (GO:0051966)2.89867914
105opioid receptor signaling pathway (GO:0038003)2.88729620
106regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.88476449
107acidic amino acid transport (GO:0015800)2.88229682
108long-term synaptic potentiation (GO:0060291)2.87477572
109regulation of neurotransmitter secretion (GO:0046928)2.85385719
110response to amphetamine (GO:0001975)2.85375281
111L-fucose catabolic process (GO:0042355)2.85257319
112fucose catabolic process (GO:0019317)2.85257319
113L-fucose metabolic process (GO:0042354)2.85257319
114positive regulation of CREB transcription factor activity (GO:0032793)2.84572775
115prepulse inhibition (GO:0060134)2.84335950
116negative regulation of neurotransmitter secretion (GO:0046929)2.82729292
117positive regulation of membrane potential (GO:0045838)2.82522391
118membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.80774363
119regulation of long-term neuronal synaptic plasticity (GO:0048169)2.80527142
120positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-2.80505872
121calcium-mediated signaling using intracellular calcium source (GO:0035584)2.80421624
122G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.78678809
123neurotransmitter metabolic process (GO:0042133)2.78503449
124regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.78373922
125synaptic transmission (GO:0007268)2.77693782
126regulation of synapse assembly (GO:0051963)2.77402640
127regulation of voltage-gated calcium channel activity (GO:1901385)2.76941812
128cerebellar Purkinje cell differentiation (GO:0021702)2.76163373
129positive regulation of synaptic transmission, GABAergic (GO:0032230)2.76147289
130behavioral response to ethanol (GO:0048149)2.75558580
131respiratory electron transport chain (GO:0022904)2.75535206
132regulation of neuronal synaptic plasticity (GO:0048168)2.73932436
133adult behavior (GO:0030534)2.73630309
134L-glutamate transport (GO:0015813)2.64852478
135positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.64164826
136cerebellar granule cell differentiation (GO:0021707)2.63681502
137potassium ion transmembrane transport (GO:0071805)2.63518349
138cellular potassium ion transport (GO:0071804)2.63518349
139neuromuscular synaptic transmission (GO:0007274)2.62045050
140neuronal action potential (GO:0019228)2.59742787
141cell differentiation in hindbrain (GO:0021533)2.59530891
142long-term memory (GO:0007616)2.58127258
143atrial cardiac muscle cell action potential (GO:0086014)2.54683169
144auditory receptor cell stereocilium organization (GO:0060088)2.54423562
145cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.54311617
146regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.53238951
147protein K11-linked deubiquitination (GO:0035871)2.52527741
148potassium ion transport (GO:0006813)2.51057275
149detection of light stimulus involved in visual perception (GO:0050908)2.49245292
150detection of light stimulus involved in sensory perception (GO:0050962)2.49245292
151inositol phosphate catabolic process (GO:0071545)2.45253653
152intraspecies interaction between organisms (GO:0051703)2.43861564
153social behavior (GO:0035176)2.43861564
154regulation of calcium ion-dependent exocytosis (GO:0017158)2.41897645

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.35738747
2GBX2_23144817_ChIP-Seq_PC3_Human4.21574970
3TAF15_26573619_Chip-Seq_HEK293_Human3.21509175
4GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse3.02036049
5SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.98478736
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.91070802
7GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.84339370
8JARID2_20064375_ChIP-Seq_MESCs_Mouse2.63230481
9SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.53422266
10SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.49365076
11SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.40873500
12EED_16625203_ChIP-ChIP_MESCs_Mouse2.39524129
13EZH2_27304074_Chip-Seq_ESCs_Mouse2.30408814
14JARID2_20075857_ChIP-Seq_MESCs_Mouse2.29788085
15ZFP57_27257070_Chip-Seq_ESCs_Mouse2.28809379
16RNF2_18974828_ChIP-Seq_MESCs_Mouse2.21605628
17EZH2_18974828_ChIP-Seq_MESCs_Mouse2.21605628
18BMI1_23680149_ChIP-Seq_NPCS_Mouse2.21408387
19NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.16029645
20MTF2_20144788_ChIP-Seq_MESCs_Mouse2.15348436
21IGF1R_20145208_ChIP-Seq_DFB_Human2.11938076
22SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.11202489
23RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.09897713
24CTBP2_25329375_ChIP-Seq_LNCAP_Human2.09588892
25REST_21632747_ChIP-Seq_MESCs_Mouse2.03386489
26CTBP1_25329375_ChIP-Seq_LNCAP_Human2.02444345
27CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.98549296
28POU3F2_20337985_ChIP-ChIP_501MEL_Human1.93797593
29ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.92153845
30TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.91836517
31EZH2_27294783_Chip-Seq_ESCs_Mouse1.91331962
32P300_19829295_ChIP-Seq_ESCs_Human1.90836245
33PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.86708743
34SUZ12_27294783_Chip-Seq_ESCs_Mouse1.86082508
35IKZF1_21737484_ChIP-ChIP_HCT116_Human1.80529288
36SMAD4_21799915_ChIP-Seq_A2780_Human1.76879185
37RNF2_27304074_Chip-Seq_ESCs_Mouse1.76666107
38DROSHA_22980978_ChIP-Seq_HELA_Human1.71048917
39FUS_26573619_Chip-Seq_HEK293_Human1.71030470
40PIAS1_25552417_ChIP-Seq_VCAP_Human1.67829555
41ER_23166858_ChIP-Seq_MCF-7_Human1.66893978
42PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.66503385
43REST_18959480_ChIP-ChIP_MESCs_Mouse1.62320422
44AR_21572438_ChIP-Seq_LNCaP_Human1.61523308
45TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.60657694
46POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.60657694
47CBX2_27304074_Chip-Seq_ESCs_Mouse1.59582827
48RNF2_27304074_Chip-Seq_NSC_Mouse1.56723521
49SMAD3_21741376_ChIP-Seq_EPCs_Human1.53235754
50SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.52495640
51SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.51769790
52TOP2B_26459242_ChIP-Seq_MCF-7_Human1.49850953
53OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.48344073
54RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.46426125
55VDR_22108803_ChIP-Seq_LS180_Human1.45774308
56STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.42313018
57IRF8_22096565_ChIP-ChIP_GC-B_Human1.41135754
58UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.40992636
59NR3C1_23031785_ChIP-Seq_PC12_Mouse1.39503455
60FLI1_27457419_Chip-Seq_LIVER_Mouse1.38012227
61CDX2_19796622_ChIP-Seq_MESCs_Mouse1.35111627
62PCGF2_27294783_Chip-Seq_ESCs_Mouse1.34824638
63SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.33055113
64EWS_26573619_Chip-Seq_HEK293_Human1.31031735
65NANOG_18555785_Chip-Seq_ESCs_Mouse1.31003135
66TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.29523197
67AR_25329375_ChIP-Seq_VCAP_Human1.26373894
68EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.23478043
69PRDM14_20953172_ChIP-Seq_ESCs_Human1.23317613
70SMAD_19615063_ChIP-ChIP_OVARY_Human1.23002544
71ZNF274_21170338_ChIP-Seq_K562_Hela1.22842097
72FLI1_21867929_ChIP-Seq_TH2_Mouse1.21998236
73STAT3_23295773_ChIP-Seq_U87_Human1.21422658
74TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.20569616
75RUNX2_22187159_ChIP-Seq_PCA_Human1.19694204
76PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.19413681
77TCF4_23295773_ChIP-Seq_U87_Human1.18577110
78CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18390712
79SOX2_21211035_ChIP-Seq_LN229_Gbm1.17220796
80JUN_21703547_ChIP-Seq_K562_Human1.17163460
81CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.15122875
82MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.14539266
83AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.12861583
84SUZ12_27294783_Chip-Seq_NPCs_Mouse1.12623829
85RARB_27405468_Chip-Seq_BRAIN_Mouse1.12293616
86E2F1_18555785_Chip-Seq_ESCs_Mouse1.11867719
87TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.11705605
88TP53_22573176_ChIP-Seq_HFKS_Human1.11358701
89P53_22387025_ChIP-Seq_ESCs_Mouse1.07982222
90TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07774638
91AR_19668381_ChIP-Seq_PC3_Human1.07422683
92CMYC_18555785_Chip-Seq_ESCs_Mouse1.07409871
93CBP_20019798_ChIP-Seq_JUKART_Human1.07327046
94IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.07327046
95RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.06137940
96SMAD4_21741376_ChIP-Seq_EPCs_Human1.05926735
97BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.05814211
98NR3C1_21868756_ChIP-Seq_MCF10A_Human1.05091525
99TCF4_22108803_ChIP-Seq_LS180_Human1.04849225
100EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.04675276
101TP53_18474530_ChIP-ChIP_U2OS_Human1.02907398
102KLF5_20875108_ChIP-Seq_MESCs_Mouse1.02904904
103SUZ12_18555785_Chip-Seq_ESCs_Mouse1.02844957
104ETV2_25802403_ChIP-Seq_MESCs_Mouse1.02740044
105MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.02564404
106STAT3_18555785_Chip-Seq_ESCs_Mouse1.02278481
107TAL1_26923725_Chip-Seq_HPCs_Mouse0.99166908
108EZH2_27294783_Chip-Seq_NPCs_Mouse0.98625609
109KDM2B_26808549_Chip-Seq_REH_Human0.98403600
110RUNX_20019798_ChIP-Seq_JUKART_Human0.98249344
111SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.97939052
112RING1B_27294783_Chip-Seq_ESCs_Mouse0.97646182
113P300_18555785_Chip-Seq_ESCs_Mouse0.97467811
114PCGF2_27294783_Chip-Seq_NPCs_Mouse0.97461191
115RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.96497168
116MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.96341449
117TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.96117602
118NFE2_27457419_Chip-Seq_LIVER_Mouse0.96089383
119RUNX1_27457419_Chip-Seq_LIVER_Mouse0.95021424
120NANOG_19829295_ChIP-Seq_ESCs_Human0.94988559
121SOX2_19829295_ChIP-Seq_ESCs_Human0.94988559
122VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.94753185
123SOX2_18555785_Chip-Seq_ESCs_Mouse0.94676492
124POU5F1_16153702_ChIP-ChIP_HESCs_Human0.94426006
125MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.94302906
126FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.93367762
127* GATA3_21878914_ChIP-Seq_MCF-7_Human0.93357925
128ARNT_22903824_ChIP-Seq_MCF-7_Human0.93339295
129CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.91806589
130CRX_20693478_ChIP-Seq_RETINA_Mouse0.91649481
131BCAT_22108803_ChIP-Seq_LS180_Human0.90980511
132P53_22127205_ChIP-Seq_FIBROBLAST_Human0.90786337

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern5.84745041
2MP0006276_abnormal_autonomic_nervous3.81122734
3MP0004859_abnormal_synaptic_plasticity3.46660600
4MP0001529_abnormal_vocalization3.30418495
5MP0003635_abnormal_synaptic_transmissio3.18932242
6MP0001905_abnormal_dopamine_level3.12517924
7MP0002822_catalepsy3.07832098
8MP0009745_abnormal_behavioral_response3.03200948
9MP0009046_muscle_twitch3.03030198
10MP0002064_seizures2.94101768
11MP0001188_hyperpigmentation2.88424952
12MP0001968_abnormal_touch/_nociception2.65826516
13MP0004885_abnormal_endolymph2.63757502
14MP0004270_analgesia2.63522915
15MP0005423_abnormal_somatic_nervous2.54189329
16MP0002572_abnormal_emotion/affect_behav2.48472129
17MP0002272_abnormal_nervous_system2.48411352
18MP0001501_abnormal_sleep_pattern2.47562528
19MP0005409_darkened_coat_color2.41511391
20MP0002063_abnormal_learning/memory/cond2.37936498
21MP0001486_abnormal_startle_reflex2.34301590
22MP0000569_abnormal_digit_pigmentation2.33638352
23MP0002734_abnormal_mechanical_nocicepti2.29869304
24MP0002736_abnormal_nociception_after2.26225271
25MP0002735_abnormal_chemical_nociception2.21038362
26MP0003122_maternal_imprinting2.02409640
27MP0002067_abnormal_sensory_capabilities1.93996477
28MP0002733_abnormal_thermal_nociception1.93154238
29MP0001970_abnormal_pain_threshold1.86281202
30MP0001440_abnormal_grooming_behavior1.85153106
31MP0004924_abnormal_behavior1.84153404
32MP0005386_behavior/neurological_phenoty1.84153404
33MP0004142_abnormal_muscle_tone1.81077598
34MP0001485_abnormal_pinna_reflex1.77693700
35MP0005646_abnormal_pituitary_gland1.72348494
36MP0003787_abnormal_imprinting1.68444059
37MP0010386_abnormal_urinary_bladder1.65035619
38MP0005171_absent_coat_pigmentation1.63475008
39MP0002184_abnormal_innervation1.58538686
40MP0005645_abnormal_hypothalamus_physiol1.55807403
41MP0002557_abnormal_social/conspecific_i1.53681010
42MP0000778_abnormal_nervous_system1.46862214
43MP0002638_abnormal_pupillary_reflex1.44103779
44MP0005551_abnormal_eye_electrophysiolog1.43414249
45MP0008569_lethality_at_weaning1.41929855
46MP0001984_abnormal_olfaction1.40421004
47MP0008872_abnormal_physiological_respon1.25267705
48MP0005377_hearing/vestibular/ear_phenot1.24126319
49MP0003878_abnormal_ear_physiology1.24126319
50MP0002066_abnormal_motor_capabilities/c1.22683617
51MP0000955_abnormal_spinal_cord1.20513319
52MP0003690_abnormal_glial_cell1.19126383
53MP0002882_abnormal_neuron_morphology1.15627568
54MP0003646_muscle_fatigue1.13305976
55MP0008995_early_reproductive_senescence1.12336013
56MP0001986_abnormal_taste_sensitivity1.10823823
57MP0004742_abnormal_vestibular_system1.08131246
58MP0004043_abnormal_pH_regulation1.07182417
59MP0002876_abnormal_thyroid_physiology1.05297712
60MP0001502_abnormal_circadian_rhythm1.05211184
61MP0005167_abnormal_blood-brain_barrier1.04511077
62MP0002837_dystrophic_cardiac_calcinosis1.04419087
63MP0004811_abnormal_neuron_physiology1.03365434
64MP0000631_abnormal_neuroendocrine_gland1.02803394
65MP0000751_myopathy1.02779558
66MP0009379_abnormal_foot_pigmentation1.02587267
67MP0000013_abnormal_adipose_tissue1.00281654
68MP0006292_abnormal_olfactory_placode0.99711826
69MP0001664_abnormal_digestion0.97493850
70MP0003879_abnormal_hair_cell0.97486868
71MP0006072_abnormal_retinal_apoptosis0.95233353
72MP0003045_fibrosis0.94313811
73MP0003631_nervous_system_phenotype0.93725251
74MP0005075_abnormal_melanosome_morpholog0.93566847
75MP0000920_abnormal_myelination0.93459314
76MP0005535_abnormal_body_temperature0.92747045
77MP0003172_abnormal_lysosome_physiology0.91927930
78MP0002229_neurodegeneration0.91166546
79MP0002332_abnormal_exercise_endurance0.88566600
80MP0006035_abnormal_mitochondrial_morpho0.88478652
81MP0005394_taste/olfaction_phenotype0.88476409
82MP0005499_abnormal_olfactory_system0.88476409
83MP0003632_abnormal_nervous_system0.88124538
84MP0004085_abnormal_heartbeat0.88017177
85MP0001963_abnormal_hearing_physiology0.85855954
86MP0002752_abnormal_somatic_nervous0.85710340
87MP0004147_increased_porphyrin_level0.84572268
88MP0003633_abnormal_nervous_system0.83512604
89MP0004858_abnormal_nervous_system0.82420171
90MP0004215_abnormal_myocardial_fiber0.82311046
91MP0005379_endocrine/exocrine_gland_phen0.81527342
92MP0002152_abnormal_brain_morphology0.81506084
93MP0003121_genomic_imprinting0.81389940
94MP0002138_abnormal_hepatobiliary_system0.81007794
95MP0000538_abnormal_urinary_bladder0.78780051
96MP0004883_abnormal_blood_vessel0.78531244
97MP0002069_abnormal_eating/drinking_beha0.78292102
98MP0005174_abnormal_tail_pigmentation0.76934929
99MP0004145_abnormal_muscle_electrophysio0.76200763
100MP0002751_abnormal_autonomic_nervous0.76165866
101MP0004272_abnormal_basement_membrane0.75380438
102MP0002090_abnormal_vision0.75208795
103MP0003698_abnormal_male_reproductive0.75127344
104MP0002095_abnormal_skin_pigmentation0.73414797
105MP0001835_abnormal_antigen_presentation0.73083395
106MP0005410_abnormal_fertilization0.71688938
107MP0003634_abnormal_glial_cell0.70735048
108MP0009764_decreased_sensitivity_to0.70529964
109MP0005253_abnormal_eye_physiology0.69252640
110MP0002653_abnormal_ependyma_morphology0.68425982
111MP0008877_abnormal_DNA_methylation0.67825431
112MP0005671_abnormal_response_to0.67737121
113MP0005623_abnormal_meninges_morphology0.66227723
114MP0009780_abnormal_chondrocyte_physiolo0.65809000
115MP0002909_abnormal_adrenal_gland0.65005556
116MP0003137_abnormal_impulse_conducting0.64634370
117MP0002102_abnormal_ear_morphology0.64485235
118MP0000015_abnormal_ear_pigmentation0.64429888
119MP0006036_abnormal_mitochondrial_physio0.64418649
120MP0001765_abnormal_ion_homeostasis0.63515486
121MP0003329_amyloid_beta_deposits0.63035447
122MP0004130_abnormal_muscle_cell0.61607065
123MP0004381_abnormal_hair_follicle0.61084336
124MP0008874_decreased_physiological_sensi0.60801517
125MP0001943_abnormal_respiration0.60235603
126MP0001177_atelectasis0.60131776
127MP0005670_abnormal_white_adipose0.59274711
128MP0001800_abnormal_humoral_immune0.58750239
129MP0000026_abnormal_inner_ear0.58558339
130MP0004036_abnormal_muscle_relaxation0.57931558
131MP0000427_abnormal_hair_cycle0.57300411
132MP0008789_abnormal_olfactory_epithelium0.56442457

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.38070949
2Limb dystonia (HP:0002451)5.68641919
3Febrile seizures (HP:0002373)4.54077169
4Atonic seizures (HP:0010819)4.46456665
5Focal seizures (HP:0007359)4.40115809
6Hypothermia (HP:0002045)4.22304358
7Epileptic encephalopathy (HP:0200134)4.16643660
8Progressive cerebellar ataxia (HP:0002073)3.79031561
9Acute necrotizing encephalopathy (HP:0006965)3.76441267
10Myokymia (HP:0002411)3.76371642
11Visual hallucinations (HP:0002367)3.70332916
12Pheochromocytoma (HP:0002666)3.64432823
13Genetic anticipation (HP:0003743)3.43634087
14Abnormal hair whorl (HP:0010721)3.35795379
15Neuroendocrine neoplasm (HP:0100634)3.30086565
16Absence seizures (HP:0002121)3.29059863
17Abnormal mitochondria in muscle tissue (HP:0008316)3.28758132
18Dialeptic seizures (HP:0011146)3.26286970
19Generalized tonic-clonic seizures (HP:0002069)3.25642978
20Mitochondrial inheritance (HP:0001427)3.20268354
21Progressive macrocephaly (HP:0004481)3.18887222
22Cerebral hypomyelination (HP:0006808)3.13063906
23Congenital stationary night blindness (HP:0007642)3.08670822
24Hemiplegia (HP:0002301)3.00806028
25Papilledema (HP:0001085)2.92720892
26Failure to thrive in infancy (HP:0001531)2.91896526
27Broad-based gait (HP:0002136)2.86287364
28Genital tract atresia (HP:0001827)2.84265781
29Postural instability (HP:0002172)2.81450154
30Polyphagia (HP:0002591)2.81314110
31Vaginal atresia (HP:0000148)2.80715672
32Attenuation of retinal blood vessels (HP:0007843)2.77244506
33Hypoplastic nipples (HP:0002557)2.75613049
34Chronic hepatic failure (HP:0100626)2.73607672
35Abnormal pupillary function (HP:0007686)2.70934796
36Acute encephalopathy (HP:0006846)2.66715920
37Stomach cancer (HP:0012126)2.65626364
38Absent speech (HP:0001344)2.63267563
39Impaired smooth pursuit (HP:0007772)2.60163941
40Medial flaring of the eyebrow (HP:0010747)2.59399821
41Gait imbalance (HP:0002141)2.58575422
42Prolonged QT interval (HP:0001657)2.53450723
43Anxiety (HP:0000739)2.52794861
44Increased CSF lactate (HP:0002490)2.51249507
45Asymmetry of the thorax (HP:0001555)2.49094479
46Abnormality of the renal cortex (HP:0011035)2.46188436
47Hypoventilation (HP:0002791)2.40235006
48Optic disc pallor (HP:0000543)2.40074196
49Congenital primary aphakia (HP:0007707)2.39996444
50Inability to walk (HP:0002540)2.39188414
51Increased corneal curvature (HP:0100692)2.37514559
52Keratoconus (HP:0000563)2.37514559
53Metabolic alkalosis (HP:0200114)2.37418402
54Abnormality of the renal medulla (HP:0100957)2.37407329
55Status epilepticus (HP:0002133)2.35776418
56Dysmetria (HP:0001310)2.35068660
57Esotropia (HP:0000565)2.33829631
58Hypokalemic alkalosis (HP:0001949)2.33547469
59Gaze-evoked nystagmus (HP:0000640)2.30802608
60Supranuclear gaze palsy (HP:0000605)2.30364385
61Stomatitis (HP:0010280)2.30192967
62Hemiparesis (HP:0001269)2.27855886
63Absent/shortened dynein arms (HP:0200106)2.26857493
64Dynein arm defect of respiratory motile cilia (HP:0012255)2.26857493
65Abnormal EKG (HP:0003115)2.25523709
66Decreased central vision (HP:0007663)2.24571662
67Nephrogenic diabetes insipidus (HP:0009806)2.23624768
68Cerebral hemorrhage (HP:0001342)2.23279509
69Nephronophthisis (HP:0000090)2.22752115
70Truncal ataxia (HP:0002078)2.22412015
71Abnormality of ocular smooth pursuit (HP:0000617)2.21580558
72Abnormality of the fingertips (HP:0001211)2.21419352
73Hyperventilation (HP:0002883)2.19911292
74Spastic gait (HP:0002064)2.18642805
75Hepatocellular necrosis (HP:0001404)2.18334657
76Palpebral edema (HP:0100540)2.16499460
77Clumsiness (HP:0002312)2.15240056
78Increased hepatocellular lipid droplets (HP:0006565)2.14950095
79Poor eye contact (HP:0000817)2.14911823
80Fetal akinesia sequence (HP:0001989)2.14890389
81Protruding tongue (HP:0010808)2.13604435
82Abnormal eating behavior (HP:0100738)2.13526995
83Renal Fanconi syndrome (HP:0001994)2.12798715
84Urinary bladder sphincter dysfunction (HP:0002839)2.12388506
85Annular pancreas (HP:0001734)2.11958318
86Retinal dysplasia (HP:0007973)2.11057826
87Pancreatic cysts (HP:0001737)2.09831416
88Dyskinesia (HP:0100660)2.07642182
89Polyuria (HP:0000103)2.06820518
90Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.06729384
91Degeneration of the lateral corticospinal tracts (HP:0002314)2.06729384
92Abnormal ciliary motility (HP:0012262)2.05288362
93Neurofibrillary tangles (HP:0002185)2.04905068
94Widely spaced teeth (HP:0000687)2.01025246
95Type II lissencephaly (HP:0007260)2.00682751
96Progressive inability to walk (HP:0002505)1.99955666
97Polydipsia (HP:0001959)1.99824329
98Abnormal drinking behavior (HP:0030082)1.99824329
99Stereotypic behavior (HP:0000733)1.99442940
100Hypsarrhythmia (HP:0002521)1.98220479
101Dysdiadochokinesis (HP:0002075)1.95402883
102Diplopia (HP:0000651)1.94083796
103Abnormality of binocular vision (HP:0011514)1.94083796
104Leukodystrophy (HP:0002415)1.93093099
105Drooling (HP:0002307)1.91625002
106Agammaglobulinemia (HP:0004432)1.91607333
107Thyroid-stimulating hormone excess (HP:0002925)1.90775656
108Delusions (HP:0000746)1.90436446
109True hermaphroditism (HP:0010459)1.90111186
110Epileptiform EEG discharges (HP:0011182)1.89860139
111Poor suck (HP:0002033)1.89295676
112Abnormality of the corticospinal tract (HP:0002492)1.89052167
113Aplasia/Hypoplasia of the lens (HP:0008063)1.88904357
114Action tremor (HP:0002345)1.88753026
115Abnormal respiratory motile cilium morphology (HP:0005938)1.88672459
116Abnormal respiratory epithelium morphology (HP:0012253)1.88672459
1173-Methylglutaconic aciduria (HP:0003535)1.87889189
118Impaired vibratory sensation (HP:0002495)1.87792377
119Amblyopia (HP:0000646)1.87508284
120CNS hypomyelination (HP:0003429)1.85820220
121Intestinal atresia (HP:0011100)1.85761964
122Narrow nasal bridge (HP:0000446)1.84323155
123Poor coordination (HP:0002370)1.83878710
124Mutism (HP:0002300)1.83616042
125Lissencephaly (HP:0001339)1.83141610
126Scanning speech (HP:0002168)1.82929157
127Abnormality of the labia minora (HP:0012880)1.82887717
128Volvulus (HP:0002580)1.82399555
129Ankle clonus (HP:0011448)1.82363942
130Excessive salivation (HP:0003781)1.81337998
131Progressive microcephaly (HP:0000253)1.81029952
132Akinesia (HP:0002304)1.79983058
133Bradykinesia (HP:0002067)1.79769462
134Hyperaldosteronism (HP:0000859)1.79541634
135Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.78954286
136Diminished movement (HP:0002374)1.78819400
137Abnormality of midbrain morphology (HP:0002418)1.77863151
138Molar tooth sign on MRI (HP:0002419)1.77863151
139Potter facies (HP:0002009)1.77771555
140Facial shape deformation (HP:0011334)1.77771555
141Delayed gross motor development (HP:0002194)1.77768903
142Sleep apnea (HP:0010535)1.77745488
143Abolished electroretinogram (ERG) (HP:0000550)1.77494485
144EEG with generalized epileptiform discharges (HP:0011198)1.77494258
145Cerebral inclusion bodies (HP:0100314)1.77035190
146Obstructive sleep apnea (HP:0002870)1.74572486
147Abnormality of macular pigmentation (HP:0008002)1.74130547
148Short chin (HP:0000331)1.73754312
149Pancreatic fibrosis (HP:0100732)1.73610124
150Muscle hypertrophy of the lower extremities (HP:0008968)1.72931169
151Increased circulating renin level (HP:0000848)1.72060552
152Cystic liver disease (HP:0006706)1.71810199
153Autoamputation (HP:0001218)1.70773494
154Myoclonus (HP:0001336)1.70374966
155Unsteady gait (HP:0002317)1.69595684
156Depression (HP:0000716)1.68513073
157Bradycardia (HP:0001662)1.68017670
158Blue irides (HP:0000635)1.67995143
159Abnormal rod and cone electroretinograms (HP:0008323)1.66849307
160Gastroesophageal reflux (HP:0002020)1.66524459
161Abnormality of calcium-phosphate metabolism (HP:0100530)1.63504869
162Abnormal urine output (HP:0012590)1.62859812

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK3.45391742
2FRK3.36452762
3DAPK23.33010554
4MAP3K123.07172867
5NTRK32.95775186
6PNCK2.89845867
7MAP2K72.81769113
8EPHA42.78373395
9TNIK2.56819028
10MARK12.34137860
11MAP3K42.28374928
12CDK192.26280893
13AKT32.12236068
14PLK21.95172139
15MAPKAPK51.93347971
16GRK51.91471995
17MYLK1.90649361
18OXSR11.89307776
19TAOK31.87884882
20MAP2K41.86572624
21STK391.85900369
22NTRK21.77802154
23RIPK41.76021106
24MAPK131.67479449
25ARAF1.63978062
26FGFR21.63705890
27STK161.61854898
28MAP4K21.59731996
29CAMKK21.59369835
30GRK71.59013448
31TRIM281.58233583
32BMPR21.54180377
33CAMKK11.53597273
34MINK11.49962908
35NTRK11.46640652
36NME11.42051826
37TSSK61.40489073
38CSNK1G31.29529348
39ADRBK21.26902302
40CAMK2B1.26853518
41CAMK2A1.24916654
42NUAK11.23783740
43CAMK41.21207300
44TXK1.21023243
45ZAK1.15188434
46FES1.11533345
47BCR1.06603412
48PRPF4B1.06393293
49CSNK1G21.05968753
50PRKCE1.05916325
51PRKCG1.05810335
52MAP3K91.05774107
53PRKD31.04785895
54TYRO31.01246102
55WNK30.99433742
56CDK50.98568535
57UHMK10.98260045
58IKBKE0.97396203
59TNK20.95170005
60SGK30.95037632
61SGK4940.94389413
62SGK2230.94389413
63STK110.92999610
64WNK40.92632491
65RIPK10.92490549
66PRKCH0.92098404
67SYK0.89935113
68CAMK2D0.88833031
69MAP2K60.88658232
70CSNK1G10.87322050
71ADRBK10.84811380
72WNK10.84178166
73YES10.82147503
74KIT0.81901765
75EPHA30.81148272
76MAP3K70.80995707
77MST40.78783824
78BMPR1B0.78071356
79NEK60.78023609
80CSNK1A1L0.76906033
81CAMK2G0.75166500
82PKN10.73397837
83MAP4K10.73310159
84ERBB40.73234011
85FGR0.70842156
86SGK20.70730904
87ITK0.69523365
88PTK2B0.67820438
89MARK20.63954023
90PAK60.63026383
91PINK10.62468675
92CDK180.61089964
93GRK10.61088670
94ERBB20.59095497
95FGFR30.58158900
96ACVR1B0.58076022
97CAMK10.57113318
98CDK150.56515470
99SIK30.55596831
100CDC42BPA0.55478905
101PDK10.54785408
102CDK11A0.54198366
103MAP3K130.53248995
104PAK30.52977373
105BRAF0.52639560
106SIK20.51855375
107DYRK1A0.51805625
108CDK140.50480013
109PRKACA0.50093387
110PHKG20.50024457
111PHKG10.50024457
112DAPK10.49655895
113PIK3CA0.48906171
114ROCK20.48129259
115CSNK1D0.45574093
116CAMK1G0.44770723
117PIK3CG0.44518870
118MKNK20.44274821
119RPS6KA30.43923746
120IKBKB0.43443895
121CDK30.43193842
122RET0.42865483
123SGK10.42710675
124MAPK70.41903973
125MKNK10.41470815
126BTK0.41258340
127KSR10.39531678
128ABL20.38175027
129MAPK120.38131591
130PRKG10.37620791
131IRAK10.36113361
132MUSK0.34717805
133INSRR0.34636662
134PRKCA0.33460448
135STK380.33205915
136PLK30.33168520
137CDK80.30583174
138IRAK30.30017795
139BRD40.29340977

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.22638027
2Oxidative phosphorylation_Homo sapiens_hsa001903.45558950
3Synaptic vesicle cycle_Homo sapiens_hsa047213.44585033
4Collecting duct acid secretion_Homo sapiens_hsa049662.86120550
5Parkinsons disease_Homo sapiens_hsa050122.79048336
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.76292943
7GABAergic synapse_Homo sapiens_hsa047272.64736217
8Serotonergic synapse_Homo sapiens_hsa047262.54526075
9Amphetamine addiction_Homo sapiens_hsa050312.44216151
10Cocaine addiction_Homo sapiens_hsa050302.40582019
11Morphine addiction_Homo sapiens_hsa050322.36466171
12Taste transduction_Homo sapiens_hsa047422.26676637
13Circadian entrainment_Homo sapiens_hsa047132.25609836
14Alzheimers disease_Homo sapiens_hsa050102.23015484
15Glutamatergic synapse_Homo sapiens_hsa047242.16377600
16Dopaminergic synapse_Homo sapiens_hsa047282.11108950
17Vibrio cholerae infection_Homo sapiens_hsa051102.05639145
18Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.98234453
19Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.91835114
20Nitrogen metabolism_Homo sapiens_hsa009101.88646635
21Circadian rhythm_Homo sapiens_hsa047101.85564316
22Long-term depression_Homo sapiens_hsa047301.78437591
23Olfactory transduction_Homo sapiens_hsa047401.78424756
24Huntingtons disease_Homo sapiens_hsa050161.77303701
25Long-term potentiation_Homo sapiens_hsa047201.76577453
26Cholinergic synapse_Homo sapiens_hsa047251.66601951
27Salivary secretion_Homo sapiens_hsa049701.66090052
28Calcium signaling pathway_Homo sapiens_hsa040201.61199693
29Cardiac muscle contraction_Homo sapiens_hsa042601.60270146
30Phototransduction_Homo sapiens_hsa047441.58855385
31Renin secretion_Homo sapiens_hsa049241.48346539
32Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.47527643
33Insulin secretion_Homo sapiens_hsa049111.44380457
34Rheumatoid arthritis_Homo sapiens_hsa053231.39009281
35Linoleic acid metabolism_Homo sapiens_hsa005911.37395688
36Fatty acid elongation_Homo sapiens_hsa000621.27942110
37Intestinal immune network for IgA production_Homo sapiens_hsa046721.26508953
38ABC transporters_Homo sapiens_hsa020101.23626300
39alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.22762101
40Asthma_Homo sapiens_hsa053101.22306749
41Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.22186983
42Primary immunodeficiency_Homo sapiens_hsa053401.17956557
43Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.10261841
44Gap junction_Homo sapiens_hsa045401.09105974
45Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.08547078
46Carbohydrate digestion and absorption_Homo sapiens_hsa049731.08051552
47Gastric acid secretion_Homo sapiens_hsa049711.06117680
48Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.05673840
49Aldosterone synthesis and secretion_Homo sapiens_hsa049251.05218205
50Regulation of autophagy_Homo sapiens_hsa041401.04895426
51Vascular smooth muscle contraction_Homo sapiens_hsa042701.03828642
52Oxytocin signaling pathway_Homo sapiens_hsa049211.02316511
53Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.97487748
54cAMP signaling pathway_Homo sapiens_hsa040240.94143364
55Axon guidance_Homo sapiens_hsa043600.93095412
56Phenylalanine metabolism_Homo sapiens_hsa003600.87789736
57Allograft rejection_Homo sapiens_hsa053300.86593092
58Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.82040873
59Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.81475919
60SNARE interactions in vesicular transport_Homo sapiens_hsa041300.79478617
61GnRH signaling pathway_Homo sapiens_hsa049120.78191779
62African trypanosomiasis_Homo sapiens_hsa051430.76324658
63Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.75618936
64Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.74776178
65Graft-versus-host disease_Homo sapiens_hsa053320.72209381
66Ether lipid metabolism_Homo sapiens_hsa005650.69570040
67Protein export_Homo sapiens_hsa030600.69179225
68Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.67441612
69Cyanoamino acid metabolism_Homo sapiens_hsa004600.66591995
70Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.66437471
71Melanogenesis_Homo sapiens_hsa049160.65071819
72Phosphatidylinositol signaling system_Homo sapiens_hsa040700.64489050
73Tyrosine metabolism_Homo sapiens_hsa003500.61710063
74Alcoholism_Homo sapiens_hsa050340.61099589
75Dilated cardiomyopathy_Homo sapiens_hsa054140.60936410
76Phagosome_Homo sapiens_hsa041450.60111351
77Pancreatic secretion_Homo sapiens_hsa049720.59391434
78cGMP-PKG signaling pathway_Homo sapiens_hsa040220.57874115
79Dorso-ventral axis formation_Homo sapiens_hsa043200.55255047
80Estrogen signaling pathway_Homo sapiens_hsa049150.55102168
81Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.54808879
82Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.54012827
83Longevity regulating pathway - mammal_Homo sapiens_hsa042110.51821160
84One carbon pool by folate_Homo sapiens_hsa006700.50553924
85T cell receptor signaling pathway_Homo sapiens_hsa046600.50282522
86ErbB signaling pathway_Homo sapiens_hsa040120.49539331
87Type I diabetes mellitus_Homo sapiens_hsa049400.49177550
88Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.46789571
89Thyroid hormone synthesis_Homo sapiens_hsa049180.46694699
90Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.46646038
91MAPK signaling pathway_Homo sapiens_hsa040100.46598188
92Ras signaling pathway_Homo sapiens_hsa040140.46458676
93Bile secretion_Homo sapiens_hsa049760.46313819
94Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.45367324
95Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.43686396
96mTOR signaling pathway_Homo sapiens_hsa041500.43167392
97Glucagon signaling pathway_Homo sapiens_hsa049220.41482480
98Type II diabetes mellitus_Homo sapiens_hsa049300.40042723
99Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.39768949
100Choline metabolism in cancer_Homo sapiens_hsa052310.39410949
101Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.38931603
102Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.38412396
103Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.37687727
104Ovarian steroidogenesis_Homo sapiens_hsa049130.37525552
105Phospholipase D signaling pathway_Homo sapiens_hsa040720.36180856
106Mineral absorption_Homo sapiens_hsa049780.36163288
107Glycerophospholipid metabolism_Homo sapiens_hsa005640.35738258
108Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.34289695
109Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.33654162
110Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.33568885
111Sphingolipid metabolism_Homo sapiens_hsa006000.33383398
112B cell receptor signaling pathway_Homo sapiens_hsa046620.33346136
113beta-Alanine metabolism_Homo sapiens_hsa004100.32234688
114Homologous recombination_Homo sapiens_hsa034400.32162608
115Caffeine metabolism_Homo sapiens_hsa002320.30760405
116Tryptophan metabolism_Homo sapiens_hsa003800.30579842
117VEGF signaling pathway_Homo sapiens_hsa043700.27082637
118Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.24907867
119Rap1 signaling pathway_Homo sapiens_hsa040150.24298980
120Glioma_Homo sapiens_hsa052140.23055572
121Wnt signaling pathway_Homo sapiens_hsa043100.22996303
122Inositol phosphate metabolism_Homo sapiens_hsa005620.22861977
123Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.20419973
124Histidine metabolism_Homo sapiens_hsa003400.18295176
125Steroid biosynthesis_Homo sapiens_hsa001000.17046003
126Oocyte meiosis_Homo sapiens_hsa041140.15054963
127RNA polymerase_Homo sapiens_hsa030200.15034481
128Vitamin B6 metabolism_Homo sapiens_hsa007500.14854847
129Autoimmune thyroid disease_Homo sapiens_hsa053200.14728614
130Metabolic pathways_Homo sapiens_hsa011000.13662849
131Butanoate metabolism_Homo sapiens_hsa006500.13298769
132Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.12570585

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