NRIP3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle exocytosis (GO:0016079)6.17500025
2vocalization behavior (GO:0071625)6.07927984
3regulation of short-term neuronal synaptic plasticity (GO:0048172)5.96161114
4glutamate secretion (GO:0014047)5.44002494
5neuron cell-cell adhesion (GO:0007158)5.40218852
6locomotory exploration behavior (GO:0035641)5.10291388
7regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.99340994
8positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.98119623
9neuronal action potential propagation (GO:0019227)4.97213687
10regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.96811414
11neurotransmitter secretion (GO:0007269)4.95936445
12regulation of glutamate receptor signaling pathway (GO:1900449)4.94976066
13positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.89243830
14regulation of synaptic vesicle exocytosis (GO:2000300)4.77644159
15synaptic vesicle maturation (GO:0016188)4.73756948
16protein localization to synapse (GO:0035418)4.63631252
17gamma-aminobutyric acid transport (GO:0015812)4.60183364
18negative regulation of synaptic transmission, GABAergic (GO:0032229)4.35443166
19ionotropic glutamate receptor signaling pathway (GO:0035235)4.34160693
20exploration behavior (GO:0035640)4.29540895
21regulation of synaptic vesicle transport (GO:1902803)4.27468621
22positive regulation of heat generation (GO:0031652)4.25988349
23neuron-neuron synaptic transmission (GO:0007270)4.24505831
24regulation of long-term neuronal synaptic plasticity (GO:0048169)4.11699525
25neurotransmitter transport (GO:0006836)4.08178408
26gamma-aminobutyric acid signaling pathway (GO:0007214)4.06119398
27regulation of vitamin D biosynthetic process (GO:0060556)4.02639032
28positive regulation of synapse maturation (GO:0090129)4.02395339
29regulation of neuronal synaptic plasticity (GO:0048168)3.98432149
30synaptic transmission, glutamatergic (GO:0035249)3.98325088
31glutamate receptor signaling pathway (GO:0007215)3.97151790
32proline transport (GO:0015824)3.93899293
33cellular response to ATP (GO:0071318)3.90097556
34eosinophil chemotaxis (GO:0048245)3.81597091
35regulation of neurotransmitter levels (GO:0001505)3.81146880
36synaptic vesicle docking involved in exocytosis (GO:0016081)3.80615220
37long-term memory (GO:0007616)3.79837267
38neurotransmitter-gated ion channel clustering (GO:0072578)3.76704203
39kynurenine metabolic process (GO:0070189)3.73531452
40positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.70626902
41oligosaccharide catabolic process (GO:0009313)3.68707501
42regulation of heat generation (GO:0031650)3.63977349
43regulation of synapse structural plasticity (GO:0051823)3.62861591
44neuron recognition (GO:0008038)3.61849301
45long-term synaptic potentiation (GO:0060291)3.58730479
46regulation of excitatory postsynaptic membrane potential (GO:0060079)3.58212119
47regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.57454795
48membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.56763045
49regulation of fever generation (GO:0031620)3.53812276
50energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.53603524
51ATP hydrolysis coupled proton transport (GO:0015991)3.53603524
52synaptic vesicle endocytosis (GO:0048488)3.48367032
53detection of calcium ion (GO:0005513)3.45729875
54cerebellar Purkinje cell differentiation (GO:0021702)3.45429471
55layer formation in cerebral cortex (GO:0021819)3.45275256
56regulation of synaptic transmission, glutamatergic (GO:0051966)3.45194788
57positive regulation of neurotransmitter secretion (GO:0001956)3.45117952
58positive regulation of membrane potential (GO:0045838)3.44957693
59regulation of postsynaptic membrane potential (GO:0060078)3.42186941
60transmission of nerve impulse (GO:0019226)3.41155401
61indole-containing compound catabolic process (GO:0042436)3.36894879
62indolalkylamine catabolic process (GO:0046218)3.36894879
63tryptophan catabolic process (GO:0006569)3.36894879
64negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.36755328
65regulation of synaptic plasticity (GO:0048167)3.36622017
66positive regulation of prostaglandin secretion (GO:0032308)3.36203545
67eosinophil migration (GO:0072677)3.35612579
68response to histamine (GO:0034776)3.35427624
69startle response (GO:0001964)3.34859282
70transferrin transport (GO:0033572)3.31793527
71regulation of prostaglandin secretion (GO:0032306)3.30920388
72regulation of vesicle fusion (GO:0031338)3.30404454
73regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.30362620
74negative regulation of dendrite morphogenesis (GO:0050774)3.29943998
75presynaptic membrane assembly (GO:0097105)3.28589858
76regulation of neurotransmitter secretion (GO:0046928)3.25566132
77regulation of synapse maturation (GO:0090128)3.23980347
78behavioral response to cocaine (GO:0048148)3.22964758
79regulation of synaptic transmission, GABAergic (GO:0032228)3.22407009
80synaptic transmission, dopaminergic (GO:0001963)3.22136741
81mating behavior (GO:0007617)3.20529240
82positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.19809945
83negative regulation of amino acid transport (GO:0051956)3.18824945
84synaptic transmission (GO:0007268)3.17820163
85cellular potassium ion homeostasis (GO:0030007)3.16585750
86neuromuscular process controlling posture (GO:0050884)3.16412667
87response to cocaine (GO:0042220)3.14841234
88synapse assembly (GO:0007416)3.14730535
89establishment of synaptic vesicle localization (GO:0097480)3.13604116
90synaptic vesicle transport (GO:0048489)3.13604116
91intraspecies interaction between organisms (GO:0051703)3.12859235
92social behavior (GO:0035176)3.12859235
93postsynaptic membrane organization (GO:0001941)3.12288639
94succinate metabolic process (GO:0006105)3.11792557
95membrane depolarization (GO:0051899)3.10775046
96striatum development (GO:0021756)3.10448681
97axonal fasciculation (GO:0007413)3.09882662
98ferric iron transport (GO:0015682)3.09184701
99trivalent inorganic cation transport (GO:0072512)3.09184701
100activation of protein kinase A activity (GO:0034199)3.08545183
101regulation of neurotransmitter transport (GO:0051588)3.06333457
102learning (GO:0007612)3.06037009
103membrane depolarization during action potential (GO:0086010)3.05615881
104negative regulation of mast cell activation (GO:0033004)3.05557281
105presynaptic membrane organization (GO:0097090)3.04469755
106positive regulation of neurotransmitter transport (GO:0051590)3.04201691
107positive regulation of synapse assembly (GO:0051965)3.02873325
108G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.00160226
109dendritic spine morphogenesis (GO:0060997)2.99350679
110regulation of mononuclear cell migration (GO:0071675)2.99334922
111membrane hyperpolarization (GO:0060081)2.97539335
112regulation of synaptic transmission (GO:0050804)2.97297835
113phagosome maturation (GO:0090382)2.94491055
114positive regulation of synaptic transmission (GO:0050806)2.92514585
115positive regulation of synaptic transmission, GABAergic (GO:0032230)2.92139898
116regulation of glutamate secretion (GO:0014048)2.90854039
117neurotransmitter biosynthetic process (GO:0042136)2.86360927
118establishment of vesicle localization (GO:0051650)2.85025213
119negative regulation of dendrite development (GO:2000171)2.84486524
120innervation (GO:0060384)2.84427234
121cellular biogenic amine catabolic process (GO:0042402)2.82896481
122amine catabolic process (GO:0009310)2.82896481
123positive regulation of chemokine biosynthetic process (GO:0045080)2.81981952
124alanine transport (GO:0032328)2.79074621
125adult walking behavior (GO:0007628)2.75997326
126response to amphetamine (GO:0001975)2.73239066
127serotonin metabolic process (GO:0042428)2.72353870
128mitotic cell cycle arrest (GO:0071850)2.70780765
129positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.70099242
130negative regulation of interleukin-1 beta production (GO:0032691)2.68641552
131behavioral response to nicotine (GO:0035095)2.68073136
132L-amino acid import (GO:0043092)2.66451330
133monocyte chemotaxis (GO:0002548)2.65052394
134urinary tract smooth muscle contraction (GO:0014848)2.63952942
135protein localization to cilium (GO:0061512)2.63013171
136tryptophan metabolic process (GO:0006568)2.61458810
137acidic amino acid transport (GO:0015800)2.59030554
138indole-containing compound metabolic process (GO:0042430)2.57908142
139regulation of vitamin metabolic process (GO:0030656)2.56051536
140negative regulation of interleukin-12 production (GO:0032695)2.53601206
141glycosphingolipid catabolic process (GO:0046479)2.51336457
142ganglioside metabolic process (GO:0001573)2.51006232
143response to acidic pH (GO:0010447)2.47823696
144response to ATP (GO:0033198)2.47352640
145glycerophospholipid catabolic process (GO:0046475)2.45687053
146L-glutamate transport (GO:0015813)2.45590099
147C4-dicarboxylate transport (GO:0015740)2.45052913
148calcium ion-dependent exocytosis (GO:0017156)2.44045648

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.50811337
2GBX2_23144817_ChIP-Seq_PC3_Human4.12069400
3* SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.22011889
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.10070318
5JARID2_20064375_ChIP-Seq_MESCs_Mouse3.06233398
6REST_21632747_ChIP-Seq_MESCs_Mouse2.71357341
7* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.64924767
8TAF15_26573619_Chip-Seq_HEK293_Human2.62620773
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.57630540
10RNF2_18974828_ChIP-Seq_MESCs_Mouse2.57630540
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.55686308
12SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.53359633
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.49386164
14* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.42654665
15* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.41193990
16EZH2_27304074_Chip-Seq_ESCs_Mouse2.41055994
17* REST_18959480_ChIP-ChIP_MESCs_Mouse2.22901640
18EED_16625203_ChIP-ChIP_MESCs_Mouse2.22364202
19CTBP2_25329375_ChIP-Seq_LNCAP_Human2.21317549
20RARB_27405468_Chip-Seq_BRAIN_Mouse2.13703856
21CTBP1_25329375_ChIP-Seq_LNCAP_Human2.10967195
22SUZ12_27294783_Chip-Seq_ESCs_Mouse2.10566579
23DROSHA_22980978_ChIP-Seq_HELA_Human2.10411152
24ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.09713755
25IKZF1_21737484_ChIP-ChIP_HCT116_Human2.09458235
26NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.06625784
27EZH2_27294783_Chip-Seq_ESCs_Mouse2.03155145
28RNF2_27304074_Chip-Seq_ESCs_Mouse2.02455057
29GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.00657575
30TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.94654777
31SMAD4_21799915_ChIP-Seq_A2780_Human1.94629452
32BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.94284389
33CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.93624217
34ZFP57_27257070_Chip-Seq_ESCs_Mouse1.93286637
35CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.92254011
36AR_21572438_ChIP-Seq_LNCaP_Human1.79240288
37P300_19829295_ChIP-Seq_ESCs_Human1.75537758
38SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.66539574
39PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.62676762
40FLI1_27457419_Chip-Seq_LIVER_Mouse1.61318684
41* BMI1_23680149_ChIP-Seq_NPCS_Mouse1.56766954
42GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.54193342
43TOP2B_26459242_ChIP-Seq_MCF-7_Human1.52765297
44IGF1R_20145208_ChIP-Seq_DFB_Human1.51703046
45PCGF2_27294783_Chip-Seq_ESCs_Mouse1.51070641
46MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.49506858
47Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.49458313
48POU3F2_20337985_ChIP-ChIP_501MEL_Human1.47918781
49ZNF274_21170338_ChIP-Seq_K562_Hela1.46832487
50NR3C1_23031785_ChIP-Seq_PC12_Mouse1.45324650
51SMAD3_21741376_ChIP-Seq_EPCs_Human1.44873140
52IRF8_21731497_ChIP-ChIP_J774_Mouse1.44317390
53FUS_26573619_Chip-Seq_HEK293_Human1.44008355
54SOX2_21211035_ChIP-Seq_LN229_Gbm1.43919468
55* AR_25329375_ChIP-Seq_VCAP_Human1.43758719
56PIAS1_25552417_ChIP-Seq_VCAP_Human1.43615556
57SMAD_19615063_ChIP-ChIP_OVARY_Human1.42681239
58CBX2_27304074_Chip-Seq_ESCs_Mouse1.42116433
59* ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.42020493
60* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.42004354
61SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.41921430
62ERG_21242973_ChIP-ChIP_JURKAT_Human1.38773819
63SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.36738303
64PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.36079980
65PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.34980141
66STAT3_23295773_ChIP-Seq_U87_Human1.28535086
67EWS_26573619_Chip-Seq_HEK293_Human1.28415218
68* NANOG_19829295_ChIP-Seq_ESCs_Human1.27431810
69* SOX2_19829295_ChIP-Seq_ESCs_Human1.27431810
70UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.26897553
71MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.26532476
72RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.25563055
73RNF2_27304074_Chip-Seq_NSC_Mouse1.24476417
74TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.21848633
75FLI1_21867929_ChIP-Seq_TH2_Mouse1.21553945
76AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.20703229
77SMAD4_21741376_ChIP-Seq_EPCs_Human1.20570859
78MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.19442774
79VDR_22108803_ChIP-Seq_LS180_Human1.19014933
80E2F1_18555785_Chip-Seq_ESCs_Mouse1.17902585
81EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.16766393
82* TCF4_23295773_ChIP-Seq_U87_Human1.16731562
83SUZ12_18555785_Chip-Seq_ESCs_Mouse1.16578505
84ER_23166858_ChIP-Seq_MCF-7_Human1.15123336
85JUN_21703547_ChIP-Seq_K562_Human1.13977912
86TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.13914161
87VDR_24787735_ChIP-Seq_THP-1_Human1.13858141
88IRF8_27001747_Chip-Seq_BMDM_Mouse1.13477647
89RING1B_27294783_Chip-Seq_ESCs_Mouse1.13472594
90RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.13358889
91P53_22387025_ChIP-Seq_ESCs_Mouse1.12770374
92AR_19668381_ChIP-Seq_PC3_Human1.12440469
93BCAT_22108803_ChIP-Seq_LS180_Human1.11940123
94SUZ12_27294783_Chip-Seq_NPCs_Mouse1.11241935
95CDX2_19796622_ChIP-Seq_MESCs_Mouse1.10832818
96CMYC_18555785_Chip-Seq_ESCs_Mouse1.10173564
97RUNX2_22187159_ChIP-Seq_PCA_Human1.09500466
98LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.09394205
99PRDM14_20953172_ChIP-Seq_ESCs_Human1.09305367
100TP53_22573176_ChIP-Seq_HFKS_Human1.08410659
101CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08309192
102STAT3_18555785_Chip-Seq_ESCs_Mouse1.07947537
103NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.06839532
104NRF2_20460467_ChIP-Seq_MEFs_Mouse1.06839532
105EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.06485901
106EZH2_27294783_Chip-Seq_NPCs_Mouse1.05674826
107ARNT_22903824_ChIP-Seq_MCF-7_Human1.03524664
108YAP1_20516196_ChIP-Seq_MESCs_Mouse1.03190823
109MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.03156753
110P53_22127205_ChIP-Seq_FIBROBLAST_Human1.00924543
111AHR_22903824_ChIP-Seq_MCF-7_Human0.99520482
112NANOG_18555785_Chip-Seq_ESCs_Mouse0.98309804
113ZNF217_24962896_ChIP-Seq_MCF-7_Human0.97747544
114NR3C1_21868756_ChIP-Seq_MCF10A_Human0.97108690
115TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.94672837
116TP53_18474530_ChIP-ChIP_U2OS_Human0.93801943
117MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.92517920
118SMAD3_21741376_ChIP-Seq_ESCs_Human0.92461438
119TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91902756
120POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.90604523
121TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.90604523
122KDM2B_26808549_Chip-Seq_REH_Human0.90400031
123CBP_20019798_ChIP-Seq_JUKART_Human0.90329852
124IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.90329852
125DNAJC2_21179169_ChIP-ChIP_NT2_Human0.89927124
126CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.87000319
127TP53_16413492_ChIP-PET_HCT116_Human0.86466428
128WT1_25993318_ChIP-Seq_PODOCYTE_Human0.86141610
129RING1B_27294783_Chip-Seq_NPCs_Mouse0.85035444

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.67804260
2MP0003880_abnormal_central_pattern4.99026077
3MP0003635_abnormal_synaptic_transmissio4.06462257
4MP0002822_catalepsy3.69273761
5MP0009046_muscle_twitch3.62253027
6MP0000569_abnormal_digit_pigmentation3.59078552
7MP0009745_abnormal_behavioral_response3.57563990
8MP0002064_seizures3.43356279
9MP0002063_abnormal_learning/memory/cond3.16671973
10MP0004270_analgesia3.12091969
11MP0001968_abnormal_touch/_nociception3.05985261
12MP0002735_abnormal_chemical_nociception2.95300477
13MP0002572_abnormal_emotion/affect_behav2.84251382
14MP0002272_abnormal_nervous_system2.72703416
15MP0002734_abnormal_mechanical_nocicepti2.68688305
16MP0009840_abnormal_foam_cell2.61270688
17MP0001501_abnormal_sleep_pattern2.56442709
18MP0002736_abnormal_nociception_after2.54143015
19MP0001486_abnormal_startle_reflex2.40283291
20MP0006276_abnormal_autonomic_nervous2.36537981
21MP0005167_abnormal_blood-brain_barrier2.35663236
22MP0001440_abnormal_grooming_behavior2.26859122
23MP0005423_abnormal_somatic_nervous2.23665579
24MP0002733_abnormal_thermal_nociception2.20901268
25MP0002067_abnormal_sensory_capabilities2.12731599
26MP0001970_abnormal_pain_threshold2.08737439
27MP0003195_calcinosis2.03852112
28MP0003172_abnormal_lysosome_physiology2.00088835
29MP0004510_myositis1.94411541
30MP0003303_peritoneal_inflammation1.92939774
31MP0000343_altered_response_to1.92665253
32MP0002184_abnormal_innervation1.87888627
33MP0004924_abnormal_behavior1.83005693
34MP0005386_behavior/neurological_phenoty1.83005693
35MP0008569_lethality_at_weaning1.81750129
36MP0002837_dystrophic_cardiac_calcinosis1.79833257
37MP0002148_abnormal_hypersensitivity_rea1.77805394
38MP0006082_CNS_inflammation1.76276074
39MP0002557_abnormal_social/conspecific_i1.76205810
40MP0001905_abnormal_dopamine_level1.76117831
41MP0001984_abnormal_olfaction1.74499245
42MP0002139_abnormal_hepatobiliary_system1.73865247
43MP0005646_abnormal_pituitary_gland1.72221416
44MP0001529_abnormal_vocalization1.71313896
45MP0003329_amyloid_beta_deposits1.70551846
46MP0009780_abnormal_chondrocyte_physiolo1.62831622
47MP0004858_abnormal_nervous_system1.62414523
48MP0009764_decreased_sensitivity_to1.62099740
49MP0004811_abnormal_neuron_physiology1.60518397
50MP0003122_maternal_imprinting1.59561880
51MP0000920_abnormal_myelination1.57616184
52MP0002909_abnormal_adrenal_gland1.56866816
53MP0004142_abnormal_muscle_tone1.56502756
54MP0000778_abnormal_nervous_system1.55140837
55MP0003787_abnormal_imprinting1.54760107
56MP0003950_abnormal_plasma_membrane1.53317218
57MP0001188_hyperpigmentation1.52870210
58MP0003075_altered_response_to1.45382485
59MP0000955_abnormal_spinal_cord1.42637325
60MP0003879_abnormal_hair_cell1.41299278
61MP0002066_abnormal_motor_capabilities/c1.40377524
62MP0003690_abnormal_glial_cell1.38296101
63MP0005174_abnormal_tail_pigmentation1.36749371
64MP0000015_abnormal_ear_pigmentation1.35842514
65MP0002882_abnormal_neuron_morphology1.30915867
66MP0006072_abnormal_retinal_apoptosis1.29866564
67MP0005410_abnormal_fertilization1.27622300
68MP0005058_abnormal_lysosome_morphology1.27417115
69MP0010386_abnormal_urinary_bladder1.26714512
70MP0003136_yellow_coat_color1.22704146
71MP0001502_abnormal_circadian_rhythm1.16697624
72MP0005645_abnormal_hypothalamus_physiol1.15529174
73MP0002876_abnormal_thyroid_physiology1.15437217
74MP0005253_abnormal_eye_physiology1.15266989
75MP0004885_abnormal_endolymph1.12650193
76MP0008872_abnormal_physiological_respon1.10783077
77MP0003633_abnormal_nervous_system1.10114949
78MP0001986_abnormal_taste_sensitivity1.07626441
79MP0000013_abnormal_adipose_tissue1.07493553
80MP0005310_abnormal_salivary_gland1.05845770
81MP0000371_diluted_coat_color1.03924622
82MP0003631_nervous_system_phenotype1.03011725
83MP0000751_myopathy0.99395229
84MP0002102_abnormal_ear_morphology0.98047971
85MP0002152_abnormal_brain_morphology0.97862719
86MP0002229_neurodegeneration0.94938239
87MP0009785_altered_susceptibility_to0.92274092
88MP0004742_abnormal_vestibular_system0.92011908
89MP0001963_abnormal_hearing_physiology0.89747684
90MP0005535_abnormal_body_temperature0.89514774
91MP0004147_increased_porphyrin_level0.88870855
92MP0002069_abnormal_eating/drinking_beha0.88246167
93MP0008874_decreased_physiological_sensi0.87414270
94MP0004215_abnormal_myocardial_fiber0.87197721
95MP0002638_abnormal_pupillary_reflex0.86579084
96MP0004484_altered_response_of0.85483124
97MP0004085_abnormal_heartbeat0.84862076
98MP0001177_atelectasis0.83828179
99MP0003632_abnormal_nervous_system0.83635258
100MP0002254_reproductive_system_inflammat0.83246650
101MP0005551_abnormal_eye_electrophysiolog0.80619200
102MP0008875_abnormal_xenobiotic_pharmacok0.79420769
103MP0001664_abnormal_digestion0.78165139
104MP0002419_abnormal_innate_immunity0.77110862
105MP0005394_taste/olfaction_phenotype0.77001375
106MP0005499_abnormal_olfactory_system0.77001375
107MP0001324_abnormal_eye_pigmentation0.76831335
108MP0005595_abnormal_vascular_smooth0.76366050
109MP0002095_abnormal_skin_pigmentation0.76300783
110MP0002998_abnormal_bone_remodeling0.76179328
111MP0005166_decreased_susceptibility_to0.75239882
112MP0000604_amyloidosis0.74357178
113MP0003448_altered_tumor_morphology0.73754822
114MP0003646_muscle_fatigue0.73217940
115MP0002752_abnormal_somatic_nervous0.73060801
116MP0002938_white_spotting0.72931532
117MP0002090_abnormal_vision0.70486764
118MP0009278_abnormal_bone_marrow0.68015852
119MP0004145_abnormal_muscle_electrophysio0.67781890
120MP0003634_abnormal_glial_cell0.67207321
121MP0003724_increased_susceptibility_to0.66892045
122MP0000631_abnormal_neuroendocrine_gland0.63683550
123MP0005171_absent_coat_pigmentation0.63588708
124MP0003123_paternal_imprinting0.60138578
125MP0008877_abnormal_DNA_methylation0.59138309
126MP0001943_abnormal_respiration0.58238362
127MP0004233_abnormal_muscle_weight0.54857015
128MP0002332_abnormal_exercise_endurance0.52772130
129MP0005379_endocrine/exocrine_gland_phen0.51635281
130MP0005623_abnormal_meninges_morphology0.51395124
131MP0003121_genomic_imprinting0.51338062
132MP0002082_postnatal_lethality0.50040432
133MP0010770_preweaning_lethality0.50040432
134MP0003183_abnormal_peptide_metabolism0.49557558
135MP0003137_abnormal_impulse_conducting0.48993914
136MP0000026_abnormal_inner_ear0.48908510
137MP0010769_abnormal_survival0.48727074
138MP0003956_abnormal_body_size0.48711195
139MP0004043_abnormal_pH_regulation0.48602200
140MP0006035_abnormal_mitochondrial_morpho0.48514340

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)8.85744400
2Abnormality of liposaccharide metabolism (HP:0010968)5.97637130
3Abnormality of glycosphingolipid metabolism (HP:0004343)5.97637130
4Abnormality of glycolipid metabolism (HP:0010969)5.97637130
5Focal seizures (HP:0007359)5.83186291
6Myokymia (HP:0002411)5.83045765
7Atonic seizures (HP:0010819)5.75064681
8Visual hallucinations (HP:0002367)5.38958844
9Febrile seizures (HP:0002373)5.28228336
10Epileptic encephalopathy (HP:0200134)4.97171409
11Hyperventilation (HP:0002883)4.60467712
12Absence seizures (HP:0002121)4.57524489
13Progressive cerebellar ataxia (HP:0002073)4.54161977
14Dialeptic seizures (HP:0011146)4.22947490
15Generalized tonic-clonic seizures (HP:0002069)4.06402995
16Progressive inability to walk (HP:0002505)3.72877947
17Vacuolated lymphocytes (HP:0001922)3.62889061
18Increased cerebral lipofuscin (HP:0011813)3.52370139
19Limb dystonia (HP:0002451)3.49505641
20Pheochromocytoma (HP:0002666)3.36981353
21Broad-based gait (HP:0002136)3.31386408
22Disinhibition (HP:0000734)3.27315338
23Gaze-evoked nystagmus (HP:0000640)3.26196381
24Neuroendocrine neoplasm (HP:0100634)3.12854505
25Truncal ataxia (HP:0002078)3.11633981
26Inappropriate behavior (HP:0000719)3.08001711
27Action tremor (HP:0002345)3.05008038
28Amblyopia (HP:0000646)2.94039969
29Dysdiadochokinesis (HP:0002075)2.93761118
30Supranuclear gaze palsy (HP:0000605)2.92825323
31Increased neuronal autofluorescent lipopigment (HP:0002074)2.92066613
32Abnormal eating behavior (HP:0100738)2.88283300
33Abnormal social behavior (HP:0012433)2.86984625
34Impaired social interactions (HP:0000735)2.86984625
35Impaired vibration sensation in the lower limbs (HP:0002166)2.86758732
36Loss of speech (HP:0002371)2.86122554
37Apathy (HP:0000741)2.84934272
38Inability to walk (HP:0002540)2.83706996
39Poor eye contact (HP:0000817)2.83243118
40Diplopia (HP:0000651)2.76519328
41Abnormality of binocular vision (HP:0011514)2.76519328
42Anxiety (HP:0000739)2.76428954
43Depression (HP:0000716)2.74181403
44Diminished motivation (HP:0000745)2.66658129
45Epileptiform EEG discharges (HP:0011182)2.65644524
46Dysmetria (HP:0001310)2.65508592
47Polyphagia (HP:0002591)2.63718158
48Acute necrotizing encephalopathy (HP:0006965)2.63651187
49EEG with generalized epileptiform discharges (HP:0011198)2.55405326
50Absent speech (HP:0001344)2.55300953
51Abnormality of midbrain morphology (HP:0002418)2.55181357
52Molar tooth sign on MRI (HP:0002419)2.55181357
53Excessive salivation (HP:0003781)2.54290217
54Drooling (HP:0002307)2.54290217
55Stomatitis (HP:0010280)2.53073820
56Abnormal mitochondria in muscle tissue (HP:0008316)2.52104431
57Ankle clonus (HP:0011448)2.51973378
58Failure to thrive in infancy (HP:0001531)2.51203178
59Progressive macrocephaly (HP:0004481)2.51114419
60Fetal akinesia sequence (HP:0001989)2.48074692
61Dysostosis multiplex (HP:0000943)2.47915176
62Abnormal hair whorl (HP:0010721)2.46383278
63Spastic tetraparesis (HP:0001285)2.46061706
64Cerebral inclusion bodies (HP:0100314)2.46060018
65Hypsarrhythmia (HP:0002521)2.43445271
66Scanning speech (HP:0002168)2.40162571
67Gait imbalance (HP:0002141)2.40011526
68Agnosia (HP:0010524)2.39597957
69Urinary bladder sphincter dysfunction (HP:0002839)2.37872555
70Bradykinesia (HP:0002067)2.36096964
71Mutism (HP:0002300)2.34153411
72Insidious onset (HP:0003587)2.34062959
73Termporal pattern (HP:0011008)2.34062959
74Postural instability (HP:0002172)2.33181052
75Generalized myoclonic seizures (HP:0002123)2.32611661
76Neuronal loss in central nervous system (HP:0002529)2.27410191
77Status epilepticus (HP:0002133)2.27020872
78Genetic anticipation (HP:0003743)2.20001237
79Global brain atrophy (HP:0002283)2.19735247
80Hemiparesis (HP:0001269)2.15658520
81Neoplasm of the peripheral nervous system (HP:0100007)2.15023163
82Gait ataxia (HP:0002066)2.12684041
83Blue irides (HP:0000635)2.12033225
84Urinary urgency (HP:0000012)2.11131857
85Papilledema (HP:0001085)2.10688423
86Impaired smooth pursuit (HP:0007772)2.10666602
87Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.10259638
88Congenital stationary night blindness (HP:0007642)2.10142932
89Poor suck (HP:0002033)2.10141218
90Congenital primary aphakia (HP:0007707)2.09693152
91Spastic gait (HP:0002064)2.07963173
92Poor head control (HP:0002421)2.07680251
93Hyperthyroidism (HP:0000836)2.07653923
94Pancreatic fibrosis (HP:0100732)2.06363135
953-Methylglutaconic aciduria (HP:0003535)2.06354583
96Agitation (HP:0000713)2.05143895
97Abnormal drinking behavior (HP:0030082)2.03880853
98Polydipsia (HP:0001959)2.03880853
99Mitochondrial inheritance (HP:0001427)2.02980872
100Protruding tongue (HP:0010808)2.02769954
101Retinal atrophy (HP:0001105)2.02571703
102Pancreatic cysts (HP:0001737)2.01751216
103Hemiplegia (HP:0002301)2.01031699
104Medial flaring of the eyebrow (HP:0010747)2.00494606
105Neurofibrillary tangles (HP:0002185)2.00068799
106Specific learning disability (HP:0001328)1.99228938
107Cerebral hypomyelination (HP:0006808)1.98354078
108Resting tremor (HP:0002322)1.97829895
109Type II lissencephaly (HP:0007260)1.96494420
110Esotropia (HP:0000565)1.96056050
111Abnormality of ocular smooth pursuit (HP:0000617)1.96009924
112Upper limb muscle weakness (HP:0003484)1.95056904
113Hypothermia (HP:0002045)1.94498075
114Horizontal nystagmus (HP:0000666)1.94030745
115Delusions (HP:0000746)1.93275614
116Abnormality of the lower motor neuron (HP:0002366)1.92190635
117Acute encephalopathy (HP:0006846)1.91825485
118Impaired vibratory sensation (HP:0002495)1.91349401
119CNS hypomyelination (HP:0003429)1.91134001
120Spastic tetraplegia (HP:0002510)1.91119396
121Abnormality of the corticospinal tract (HP:0002492)1.90896298
122Psychosis (HP:0000709)1.90713864
123Focal dystonia (HP:0004373)1.89754099
124Nephrogenic diabetes insipidus (HP:0009806)1.89608579
125Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.89465132
126Delayed gross motor development (HP:0002194)1.88778744
127Hypoventilation (HP:0002791)1.88744474
128Decreased central vision (HP:0007663)1.88672834
129Tetraparesis (HP:0002273)1.88115900
130Dysmetric saccades (HP:0000641)1.87900455
131Autoimmune thrombocytopenia (HP:0001973)1.87653863
132Metaphyseal irregularity (HP:0003025)1.87637904
133Genital tract atresia (HP:0001827)1.87611669
134Vaginal atresia (HP:0000148)1.81238005
135Concave nail (HP:0001598)1.81060082
136Akinesia (HP:0002304)1.80911121
137Postural tremor (HP:0002174)1.80484956
138Intention tremor (HP:0002080)1.78616581
139Abnormality of polysaccharide metabolism (HP:0011012)1.78499748
140Abnormality of glycosaminoglycan metabolism (HP:0004371)1.78499748
141Abnormality of mucopolysaccharide metabolism (HP:0011020)1.78499748
142Nephronophthisis (HP:0000090)1.78319612
143Stereotypic behavior (HP:0000733)1.77393964
144Tubulointerstitial fibrosis (HP:0005576)1.73766691
145Abnormality of the periventricular white matter (HP:0002518)1.73417833
146Dementia (HP:0000726)1.72519658
147Craniofacial dystonia (HP:0012179)1.72204357
148Abnormality of macrophages (HP:0004311)1.71820976
149Torticollis (HP:0000473)1.69117559
150Optic disc pallor (HP:0000543)1.68865682
151Renal Fanconi syndrome (HP:0001994)1.67291817
152Albinism (HP:0001022)1.65008621

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.57760636
2IRAK33.82004049
3MAP3K123.79553359
4MAP3K43.62888644
5MAP3K93.40357438
6MAP2K73.32669514
7CASK3.02213692
8EPHA42.86438614
9MINK12.79513296
10MAP2K42.50274449
11MARK12.32153887
12ACVR1B2.29309689
13PNCK2.24855301
14GRK52.11565389
15NTRK21.91322456
16PLK21.88279408
17NTRK11.85917401
18ARAF1.70141804
19STK241.67844887
20RIPK41.66803976
21DAPK21.63398367
22KSR21.56434016
23PAK61.51110552
24TNIK1.49241649
25MKNK21.46858522
26DAPK11.43885171
27FES1.40225030
28CDK51.40163714
29FRK1.36409258
30DDR21.32787552
31ABL21.32747353
32CDK191.29631775
33PRKCG1.26670372
34NME11.25951366
35BMPR1B1.23079618
36KSR11.21048220
37MOS1.17682702
38MAPK131.14016866
39CAMK2A1.13857826
40CAMKK11.11516252
41LATS21.08530912
42PRKD31.07961013
43PRPF4B1.07919098
44MAP4K21.01460858
45CAMKK20.98389656
46SIK20.97830676
47STK380.97555966
48AKT30.95423794
49PTK2B0.94695541
50CSNK1G20.94484109
51WNK40.93831335
52LMTK20.92884087
53PDK30.92248028
54PDK40.92248028
55LIMK10.91408619
56MAP3K130.90336345
57TSSK60.90040469
58CAMK2B0.89957084
59TAOK20.89198352
60ZAK0.89055566
61MAP3K110.88045172
62UHMK10.87253886
63PLK30.85664946
64ERBB40.84942765
65OXSR10.84600866
66FER0.84118352
67PRKCE0.83976965
68MATK0.83380797
69MAP3K20.83218829
70STK38L0.82291604
71PHKG20.81706333
72PHKG10.81706333
73PKN10.81363306
74CDK140.81324874
75SGK4940.80435760
76SGK2230.80435760
77CDK180.80157211
78MKNK10.76228038
79FGR0.76145213
80CDK150.75790770
81SGK20.74689887
82GRK10.73619555
83DYRK1A0.73271335
84MAP3K60.71780305
85RET0.70911436
86BMPR20.70296314
87CAMK10.69803689
88CAMK2D0.67419746
89IKBKB0.66211925
90TNK20.66148786
91SCYL20.64470700
92CDK11A0.64416780
93CAMK1D0.63233782
94PRKCH0.61419414
95GRK70.60732094
96IRAK20.59922698
97RAF10.59461134
98STK110.59384400
99CAMK2G0.59212346
100INSRR0.59160815
101TGFBR20.58172905
102PAK30.57637728
103TYRO30.56880378
104SIK30.56013987
105SGK10.55525696
106MAP3K10.54050419
107PINK10.53665307
108MAPKAPK50.53455020
109MAP3K140.52742835
110MAP2K10.52493961
111GRK60.52005342
112BRAF0.51999265
113MUSK0.51808692
114CSNK1G30.51246241
115NME20.48013335
116PRKG20.47736934
117CAMK1G0.46880422
118PDK10.46758747
119SGK30.46582947
120CSNK1G10.45409953
121WNK30.45094975
122ROCK20.44934804
123ALK0.44844414
124TAOK30.44586368
125PRKCZ0.44389339
126TRIM280.44285419
127TGFBR10.44021628
128WNK10.43377563
129PDK20.43236387
130CSNK1A1L0.43179001
131ADRBK10.42253693
132TLK10.42190548
133ADRBK20.41697987
134CCNB10.40190129
135MAP2K60.39045057
136PDPK10.38931383
137RPS6KA30.37916905
138PRKACA0.37660214
139CAMK40.37261335
140GSK3A0.37122815
141CSNK1A10.35182208
142DYRK30.34306039
143TAF10.33865016
144STK390.33847938
145DYRK20.33071965

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047214.09729469
2Nicotine addiction_Homo sapiens_hsa050334.04683766
3Collecting duct acid secretion_Homo sapiens_hsa049662.89983168
4GABAergic synapse_Homo sapiens_hsa047272.89307200
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.83789218
6Lysosome_Homo sapiens_hsa041422.62998032
7Long-term potentiation_Homo sapiens_hsa047202.43251548
8Circadian entrainment_Homo sapiens_hsa047132.41311753
9Olfactory transduction_Homo sapiens_hsa047402.40710658
10Morphine addiction_Homo sapiens_hsa050322.39533949
11Amphetamine addiction_Homo sapiens_hsa050312.30782070
12Glutamatergic synapse_Homo sapiens_hsa047242.28428339
13Dopaminergic synapse_Homo sapiens_hsa047282.12919945
14Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.10007273
15Taste transduction_Homo sapiens_hsa047422.06879737
16Oxidative phosphorylation_Homo sapiens_hsa001902.02765164
17Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.02374378
18Salivary secretion_Homo sapiens_hsa049701.91510956
19Serotonergic synapse_Homo sapiens_hsa047261.84816354
20Long-term depression_Homo sapiens_hsa047301.82807085
21Insulin secretion_Homo sapiens_hsa049111.79350033
22Glycosaminoglycan degradation_Homo sapiens_hsa005311.75907319
23Vibrio cholerae infection_Homo sapiens_hsa051101.75820037
24Cholinergic synapse_Homo sapiens_hsa047251.71519228
25Gastric acid secretion_Homo sapiens_hsa049711.63941306
26Mineral absorption_Homo sapiens_hsa049781.58798830
27Cocaine addiction_Homo sapiens_hsa050301.57725782
28NOD-like receptor signaling pathway_Homo sapiens_hsa046211.53255603
29Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.50680836
30Renin secretion_Homo sapiens_hsa049241.49951353
31Calcium signaling pathway_Homo sapiens_hsa040201.48053297
32Parkinsons disease_Homo sapiens_hsa050121.47798043
33Aldosterone synthesis and secretion_Homo sapiens_hsa049251.46563582
34Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.40709666
35Cardiac muscle contraction_Homo sapiens_hsa042601.39347557
36Alzheimers disease_Homo sapiens_hsa050101.39316280
37Oxytocin signaling pathway_Homo sapiens_hsa049211.35885414
38Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.27486973
39Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.26471576
40Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.26033589
41GnRH signaling pathway_Homo sapiens_hsa049121.23375725
42Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.17900471
43Type I diabetes mellitus_Homo sapiens_hsa049401.15885491
44Gap junction_Homo sapiens_hsa045401.15781247
45Toll-like receptor signaling pathway_Homo sapiens_hsa046201.15261119
46Legionellosis_Homo sapiens_hsa051341.10778393
47Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.10606425
48Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.09659795
49Protein export_Homo sapiens_hsa030601.07875502
50Tuberculosis_Homo sapiens_hsa051521.05544336
51Other glycan degradation_Homo sapiens_hsa005111.04872932
52TNF signaling pathway_Homo sapiens_hsa046681.04855207
53Estrogen signaling pathway_Homo sapiens_hsa049151.01971809
54cAMP signaling pathway_Homo sapiens_hsa040240.98673428
55Salmonella infection_Homo sapiens_hsa051320.96458698
56Huntingtons disease_Homo sapiens_hsa050160.96405661
57Phosphatidylinositol signaling system_Homo sapiens_hsa040700.95775623
58Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.95390265
59Sphingolipid metabolism_Homo sapiens_hsa006000.95225195
60Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.95206744
61Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.95036447
62Malaria_Homo sapiens_hsa051440.93432456
63Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.93126263
64Pertussis_Homo sapiens_hsa051330.91986288
65Ether lipid metabolism_Homo sapiens_hsa005650.88029026
66Basal transcription factors_Homo sapiens_hsa030220.87691134
67Type II diabetes mellitus_Homo sapiens_hsa049300.87417667
68Nitrogen metabolism_Homo sapiens_hsa009100.86023919
69Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.84628964
70Osteoclast differentiation_Homo sapiens_hsa043800.84578490
71Melanogenesis_Homo sapiens_hsa049160.83249701
72Glioma_Homo sapiens_hsa052140.82652956
73ErbB signaling pathway_Homo sapiens_hsa040120.81553381
74Phototransduction_Homo sapiens_hsa047440.80141315
75Butanoate metabolism_Homo sapiens_hsa006500.79050088
76Vascular smooth muscle contraction_Homo sapiens_hsa042700.78374413
77cGMP-PKG signaling pathway_Homo sapiens_hsa040220.78251441
78Rheumatoid arthritis_Homo sapiens_hsa053230.78107527
79Sulfur metabolism_Homo sapiens_hsa009200.76609929
80Tryptophan metabolism_Homo sapiens_hsa003800.76493313
81Selenocompound metabolism_Homo sapiens_hsa004500.76063016
82Axon guidance_Homo sapiens_hsa043600.75219207
83Oocyte meiosis_Homo sapiens_hsa041140.70260204
84Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.67580732
85Thyroid hormone synthesis_Homo sapiens_hsa049180.64897800
86Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.64206504
87NF-kappa B signaling pathway_Homo sapiens_hsa040640.64098575
88Regulation of autophagy_Homo sapiens_hsa041400.64002989
89Pancreatic secretion_Homo sapiens_hsa049720.63581805
90Dorso-ventral axis formation_Homo sapiens_hsa043200.63070248
91Vitamin B6 metabolism_Homo sapiens_hsa007500.61941507
92Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.61624307
93Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.61436696
94Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.60369062
95Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.57513981
96Asthma_Homo sapiens_hsa053100.55099449
97Glucagon signaling pathway_Homo sapiens_hsa049220.54123405
98Phospholipase D signaling pathway_Homo sapiens_hsa040720.53303058
99Primary bile acid biosynthesis_Homo sapiens_hsa001200.52117552
100Alcoholism_Homo sapiens_hsa050340.52058654
101Dilated cardiomyopathy_Homo sapiens_hsa054140.51803183
102MAPK signaling pathway_Homo sapiens_hsa040100.51642371
103Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.50584745
104Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.49204658
105Phagosome_Homo sapiens_hsa041450.49021914
106RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.48286513
107Chemokine signaling pathway_Homo sapiens_hsa040620.47775791
108Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.46860901
109Choline metabolism in cancer_Homo sapiens_hsa052310.46227958
110Proteasome_Homo sapiens_hsa030500.45244017
111Inositol phosphate metabolism_Homo sapiens_hsa005620.45202182
112Ras signaling pathway_Homo sapiens_hsa040140.43122033
113Pyruvate metabolism_Homo sapiens_hsa006200.41829272
114Prion diseases_Homo sapiens_hsa050200.40061075
115Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.39743199
116Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.38343133
117Rap1 signaling pathway_Homo sapiens_hsa040150.37442164
118Steroid biosynthesis_Homo sapiens_hsa001000.37198755
119Leishmaniasis_Homo sapiens_hsa051400.37066264
120Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.33704529
121African trypanosomiasis_Homo sapiens_hsa051430.33084434
122Neurotrophin signaling pathway_Homo sapiens_hsa047220.31444873
123Sphingolipid signaling pathway_Homo sapiens_hsa040710.30538756
124Endocytosis_Homo sapiens_hsa041440.27930274
125Bile secretion_Homo sapiens_hsa049760.27693930
126Carbohydrate digestion and absorption_Homo sapiens_hsa049730.26168427
127Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.26160058
128Ovarian steroidogenesis_Homo sapiens_hsa049130.26074271
129Insulin signaling pathway_Homo sapiens_hsa049100.24990406
130Circadian rhythm_Homo sapiens_hsa047100.24555934
131Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.23860999
132Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.23543431
133VEGF signaling pathway_Homo sapiens_hsa043700.22922620
134Melanoma_Homo sapiens_hsa052180.22507439
135SNARE interactions in vesicular transport_Homo sapiens_hsa041300.21793363
136Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.21389550
137Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.20443630
138Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.20405343
139Thyroid hormone signaling pathway_Homo sapiens_hsa049190.19751310
140Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.19660500

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