NRSN2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)6.00874008
2synaptic vesicle maturation (GO:0016188)5.79598310
3synaptic vesicle exocytosis (GO:0016079)5.69605729
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.28898022
5vocalization behavior (GO:0071625)5.28021429
6neuromuscular process controlling posture (GO:0050884)5.11972944
7regulation of synaptic vesicle exocytosis (GO:2000300)5.06364999
8regulation of glutamate receptor signaling pathway (GO:1900449)5.01424669
9positive regulation of synaptic transmission, dopaminergic (GO:0032226)5.01397732
10neurotransmitter secretion (GO:0007269)4.95099036
11locomotory exploration behavior (GO:0035641)4.95047968
12glutamate secretion (GO:0014047)4.93664718
13regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.86790733
14regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.75566428
15positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.73782342
16neuron cell-cell adhesion (GO:0007158)4.59733561
17regulation of synaptic vesicle transport (GO:1902803)4.54254372
18neuronal action potential propagation (GO:0019227)4.31370419
19ionotropic glutamate receptor signaling pathway (GO:0035235)4.28312696
20sodium ion export (GO:0071436)4.27100319
21positive regulation of synaptic transmission, GABAergic (GO:0032230)4.26625338
22protein localization to synapse (GO:0035418)4.19062284
23neurotransmitter transport (GO:0006836)4.15630513
24gamma-aminobutyric acid transport (GO:0015812)4.12954492
25synaptic vesicle docking involved in exocytosis (GO:0016081)4.09283688
26exploration behavior (GO:0035640)4.06817652
27neuron-neuron synaptic transmission (GO:0007270)3.98418487
28regulation of long-term neuronal synaptic plasticity (GO:0048169)3.95376218
29regulation of neuronal synaptic plasticity (GO:0048168)3.95259042
30regulation of neurotransmitter levels (GO:0001505)3.95002959
31regulation of glutamate secretion (GO:0014048)3.91929522
32activation of protein kinase A activity (GO:0034199)3.90727219
33regulation of synapse structural plasticity (GO:0051823)3.84897863
34synaptic transmission, glutamatergic (GO:0035249)3.81741094
35proline transport (GO:0015824)3.81648561
36negative regulation of synaptic transmission, GABAergic (GO:0032229)3.76649108
37regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.72711027
38membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.72579056
39cerebellar Purkinje cell differentiation (GO:0021702)3.72472985
40glutamate receptor signaling pathway (GO:0007215)3.71619086
41positive regulation of synapse maturation (GO:0090129)3.70523827
42regulation of synaptic transmission, dopaminergic (GO:0032225)3.69776392
43gamma-aminobutyric acid signaling pathway (GO:0007214)3.58708651
44long-term memory (GO:0007616)3.55623448
45regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)3.50953638
46regulation of dopamine uptake involved in synaptic transmission (GO:0051584)3.50953638
47positive regulation of neurotransmitter transport (GO:0051590)3.49802493
48response to histamine (GO:0034776)3.49773984
49neurotransmitter-gated ion channel clustering (GO:0072578)3.49044979
50negative regulation of amino acid transport (GO:0051956)3.47565599
51striatum development (GO:0021756)3.47396330
52serotonin metabolic process (GO:0042428)3.45875909
53positive regulation of membrane potential (GO:0045838)3.45440666
54transmission of nerve impulse (GO:0019226)3.44559960
55regulation of vesicle fusion (GO:0031338)3.39309000
56layer formation in cerebral cortex (GO:0021819)3.36853284
57regulation of synaptic transmission, GABAergic (GO:0032228)3.35277051
58neuron recognition (GO:0008038)3.34339497
59behavioral response to cocaine (GO:0048148)3.33599663
60synaptic vesicle endocytosis (GO:0048488)3.33057933
61long-term synaptic potentiation (GO:0060291)3.31133336
62regulation of excitatory postsynaptic membrane potential (GO:0060079)3.30901690
63positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.30548889
64prepulse inhibition (GO:0060134)3.29558278
65amino acid import (GO:0043090)3.29334713
66synaptic transmission, dopaminergic (GO:0001963)3.27933506
67negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.26340254
68cellular sodium ion homeostasis (GO:0006883)3.25170383
69regulation of neurotransmitter transport (GO:0051588)3.25041946
70startle response (GO:0001964)3.24565160
71cerebellar granule cell differentiation (GO:0021707)3.23799190
72regulation of neurotransmitter uptake (GO:0051580)3.23616144
73regulation of postsynaptic membrane potential (GO:0060078)3.22999623
74positive regulation of neurotransmitter secretion (GO:0001956)3.22296462
75cellular potassium ion homeostasis (GO:0030007)3.20472349
76potassium ion homeostasis (GO:0055075)3.18939820
77regulation of neurotransmitter secretion (GO:0046928)3.18905158
78cell communication by electrical coupling (GO:0010644)3.18474206
79regulation of dendritic spine morphogenesis (GO:0061001)3.18312489
80energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.17924539
81ATP hydrolysis coupled proton transport (GO:0015991)3.17924539
82dendritic spine organization (GO:0097061)3.17572178
83adult walking behavior (GO:0007628)3.16790360
84membrane hyperpolarization (GO:0060081)3.16490746
85regulation of synaptic plasticity (GO:0048167)3.15841370
86neurotransmitter catabolic process (GO:0042135)3.15794663
87neuronal ion channel clustering (GO:0045161)3.13763948
88intraspecies interaction between organisms (GO:0051703)3.13450961
89social behavior (GO:0035176)3.13450961
90mating behavior (GO:0007617)3.13407533
91regulation of synaptic transmission, glutamatergic (GO:0051966)3.12738292
92positive regulation of dendritic spine development (GO:0060999)3.12677018
93regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.12438273
94dendritic spine morphogenesis (GO:0060997)3.12027808
95cerebellar Purkinje cell layer development (GO:0021680)3.10442821
96positive regulation of synaptic transmission (GO:0050806)3.10210594
97postsynaptic membrane organization (GO:0001941)3.10045139
98synaptic transmission (GO:0007268)3.09257216
99positive regulation of amine transport (GO:0051954)3.09122523
100transferrin transport (GO:0033572)3.07871912
101dopamine receptor signaling pathway (GO:0007212)3.07216891
102regulation of protein kinase A signaling (GO:0010738)3.06709960
103response to auditory stimulus (GO:0010996)3.06319395
104regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.05550889
105positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.04465420
106membrane depolarization during action potential (GO:0086010)3.04392300
107cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.02919633
108neurotransmitter uptake (GO:0001504)3.02755612
109regulation of female receptivity (GO:0045924)3.02508982
110female mating behavior (GO:0060180)3.02448874
111L-amino acid import (GO:0043092)2.99859582
112regulation of dopamine metabolic process (GO:0042053)2.99732666
113positive regulation of dendritic spine morphogenesis (GO:0061003)2.94910339
114negative regulation of dendrite morphogenesis (GO:0050774)2.94213245
115regulation of voltage-gated calcium channel activity (GO:1901385)2.94093797
116response to gravity (GO:0009629)2.89712701
117axonal fasciculation (GO:0007413)2.87060362
118regulation of dendritic spine development (GO:0060998)2.85919647
119detection of calcium ion (GO:0005513)2.84587546
120neuromuscular process controlling balance (GO:0050885)2.84537860
121cytoskeletal anchoring at plasma membrane (GO:0007016)2.81722973
122regulation of synapse maturation (GO:0090128)2.79849377
123presynaptic membrane assembly (GO:0097105)2.76146661
124acidic amino acid transport (GO:0015800)2.75942060
125chemosensory behavior (GO:0007635)2.75708595
126auditory behavior (GO:0031223)2.74261290
127cell migration in hindbrain (GO:0021535)2.70795035
128presynaptic membrane organization (GO:0097090)2.68794411
129establishment of synaptic vesicle localization (GO:0097480)2.58519142
130synaptic vesicle transport (GO:0048489)2.58519142
131dicarboxylic acid transport (GO:0006835)2.57780154
132protein retention in ER lumen (GO:0006621)2.57734150
133positive regulation of dendrite development (GO:1900006)2.55844724
134G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.53035694
135regulation of synaptic transmission (GO:0050804)2.52548133
136L-glutamate transport (GO:0015813)2.47946724
137potassium ion import (GO:0010107)2.47600773
138signal release (GO:0023061)2.47251652
139regulation of dendrite morphogenesis (GO:0048814)2.45995242
140cell communication involved in cardiac conduction (GO:0086065)2.43223249
141vesicle docking involved in exocytosis (GO:0006904)2.41079356
142regulation of ARF protein signal transduction (GO:0032012)2.40462577
143positive regulation of synapse assembly (GO:0051965)2.40364032
144maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.39099246
145neuromuscular synaptic transmission (GO:0007274)2.38598300

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.99697839
2GBX2_23144817_ChIP-Seq_PC3_Human3.91353254
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.25293242
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.15482722
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.98737243
6REST_21632747_ChIP-Seq_MESCs_Mouse2.93891994
7PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.81495889
8CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.80183635
9THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.78040260
10SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.66159857
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.61776494
12EZH2_18974828_ChIP-Seq_MESCs_Mouse2.61716453
13RNF2_18974828_ChIP-Seq_MESCs_Mouse2.61716453
14* RARB_27405468_Chip-Seq_BRAIN_Mouse2.58440617
15SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.57695550
16SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.57178430
17SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.55398499
18REST_18959480_ChIP-ChIP_MESCs_Mouse2.51521497
19EZH2_27304074_Chip-Seq_ESCs_Mouse2.51118433
20NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.50342950
21MTF2_20144788_ChIP-Seq_MESCs_Mouse2.50209955
22DROSHA_22980978_ChIP-Seq_HELA_Human2.34970576
23GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.34507948
24TRIM28_21343339_ChIP-Seq_HEK293_Human2.30154734
25IKZF1_21737484_ChIP-ChIP_HCT116_Human2.28406661
26TAF15_26573619_Chip-Seq_HEK293_Human2.27846096
27EED_16625203_ChIP-ChIP_MESCs_Mouse2.25571422
28SUZ12_27294783_Chip-Seq_ESCs_Mouse2.22952343
29EZH2_27294783_Chip-Seq_ESCs_Mouse2.13652517
30MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.06106795
31TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.03408984
32RNF2_27304074_Chip-Seq_ESCs_Mouse2.03165067
33CTBP2_25329375_ChIP-Seq_LNCAP_Human2.02604631
34AR_21572438_ChIP-Seq_LNCaP_Human1.96168008
35WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.83988855
36ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.80539568
37CTBP1_25329375_ChIP-Seq_LNCAP_Human1.76140391
38SMAD4_21799915_ChIP-Seq_A2780_Human1.76040575
39TET1_21490601_ChIP-Seq_MESCs_Mouse1.73807831
40ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.69985947
41ERG_21242973_ChIP-ChIP_JURKAT_Human1.64366513
42ZNF274_21170338_ChIP-Seq_K562_Hela1.63615178
43* ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.59656001
44EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.55072148
45ZFP57_27257070_Chip-Seq_ESCs_Mouse1.52711121
46BMI1_23680149_ChIP-Seq_NPCS_Mouse1.52194251
47P300_19829295_ChIP-Seq_ESCs_Human1.51789049
48GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.49568184
49KDM2B_26808549_Chip-Seq_K562_Human1.48140314
50SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.45926458
51SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.41600896
52PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.37203876
53RARG_19884340_ChIP-ChIP_MEFs_Mouse1.36614983
54NR3C1_23031785_ChIP-Seq_PC12_Mouse1.36316324
55DNAJC2_21179169_ChIP-ChIP_NT2_Human1.35797477
56TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.34814691
57* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.33756050
58OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.33321143
59SOX2_21211035_ChIP-Seq_LN229_Gbm1.32652691
60AR_25329375_ChIP-Seq_VCAP_Human1.32095630
61SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.31445378
62IGF1R_20145208_ChIP-Seq_DFB_Human1.29024920
63LXR_22292898_ChIP-Seq_THP-1_Human1.28766806
64RNF2_27304074_Chip-Seq_NSC_Mouse1.27837472
65CBX2_27304074_Chip-Seq_ESCs_Mouse1.27441377
66TOP2B_26459242_ChIP-Seq_MCF-7_Human1.25744607
67TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.25156871
68TP53_20018659_ChIP-ChIP_R1E_Mouse1.23729479
69PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.23720470
70SMAD3_21741376_ChIP-Seq_EPCs_Human1.23357267
71RING1B_27294783_Chip-Seq_ESCs_Mouse1.21646626
72CTCF_27219007_Chip-Seq_Bcells_Human1.19676119
73CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19553287
74STAT3_23295773_ChIP-Seq_U87_Human1.19128298
75ZFP281_27345836_Chip-Seq_ESCs_Mouse1.18344341
76SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.18199058
77OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.16398877
78RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.14823700
79TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.13997495
80CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.13176079
81PIAS1_25552417_ChIP-Seq_VCAP_Human1.11974638
82AR_19668381_ChIP-Seq_PC3_Human1.11407078
83POU3F2_20337985_ChIP-ChIP_501MEL_Human1.07401142
84SRY_22984422_ChIP-ChIP_TESTIS_Rat1.06354798
85PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.06150345
86MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.05311493
87SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.04751962
88ER_23166858_ChIP-Seq_MCF-7_Human1.03900488
89TCF4_23295773_ChIP-Seq_U87_Human1.03293354
90CDX2_19796622_ChIP-Seq_MESCs_Mouse1.02904674
91RUNX2_22187159_ChIP-Seq_PCA_Human1.02182083
92SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.00898591
93TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.00630257
94UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.00450292
95SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.00238980
96ZFP281_18757296_ChIP-ChIP_E14_Mouse1.00091388
97RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.99876335
98SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.99484404
99JUN_21703547_ChIP-Seq_K562_Human0.99394153
100ESR2_21235772_ChIP-Seq_MCF-7_Human0.99083020
101POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.98559499
102SMAD_19615063_ChIP-ChIP_OVARY_Human0.97768095
103CLOCK_20551151_ChIP-Seq_293T_Human0.96172872
104SMAD3_21741376_ChIP-Seq_ESCs_Human0.94834406
105WT1_25993318_ChIP-Seq_PODOCYTE_Human0.94696153
106UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.94391202
107DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.93454847
108DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.92963019
109ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.92684834
110ARNT_22903824_ChIP-Seq_MCF-7_Human0.91142534
111FUS_26573619_Chip-Seq_HEK293_Human0.91027525
112YAP1_20516196_ChIP-Seq_MESCs_Mouse0.91026173
113VDR_22108803_ChIP-Seq_LS180_Human0.90984613
114NR3C1_21868756_ChIP-Seq_MCF10A_Human0.90857178
115* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.90345925
116SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.90188158
117P53_22127205_ChIP-Seq_FIBROBLAST_Human0.89668973
118AHR_22903824_ChIP-Seq_MCF-7_Human0.89540089
119PRDM14_20953172_ChIP-Seq_ESCs_Human0.89213787
120TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88170931
121CBP_20019798_ChIP-Seq_JUKART_Human0.87720233
122IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.87720233
123TP53_23651856_ChIP-Seq_MEFs_Mouse0.87020459
124AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.86721593
125SMAD4_21741376_ChIP-Seq_HESCs_Human0.86451816
126TET1_21451524_ChIP-Seq_MESCs_Mouse0.84356193
127CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.83821187
128SMC4_20622854_ChIP-Seq_HELA_Human0.83700984
129RING1B_27294783_Chip-Seq_NPCs_Mouse0.83692167
130EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.83444904
131CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.82481889
132GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.82417817
133GATA1_26923725_Chip-Seq_HPCs_Mouse0.81804560
134ZNF263_19887448_ChIP-Seq_K562_Human0.81039495
135CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.80420509
136* CREB1_26743006_Chip-Seq_LNCaP_Human0.80376367
137MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.78723632
138* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.78420476
139WT1_19549856_ChIP-ChIP_CCG9911_Human0.78170494
140ZNF217_24962896_ChIP-Seq_MCF-7_Human0.77594924
141POU3F1_26484290_ChIP-Seq_ESCss_Mouse0.77299712
142SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.77090970
143CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.77086388
144ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.77072940
145EP300_21415370_ChIP-Seq_HL-1_Mouse0.76532870
146ISL1_27105846_Chip-Seq_CPCs_Mouse0.75288837
147SOX3_22085726_ChIP-Seq_NPCs_Mouse0.74626033
148NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.73233830
149P300_27058665_Chip-Seq_ZR-75-30cells_Human0.72767118

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.27052628
2MP0003880_abnormal_central_pattern4.60308231
3MP0003122_maternal_imprinting3.94625091
4MP0003635_abnormal_synaptic_transmissio3.90756810
5MP0009046_muscle_twitch3.58531508
6MP0009745_abnormal_behavioral_response3.43182140
7MP0002064_seizures3.27915965
8MP0002822_catalepsy3.14450115
9MP0002063_abnormal_learning/memory/cond3.04455946
10MP0001968_abnormal_touch/_nociception2.99663332
11MP0001501_abnormal_sleep_pattern2.95417231
12MP0006276_abnormal_autonomic_nervous2.94749480
13MP0002572_abnormal_emotion/affect_behav2.92370086
14MP0005645_abnormal_hypothalamus_physiol2.89601824
15MP0004270_analgesia2.78708470
16MP0002272_abnormal_nervous_system2.74258030
17MP0005423_abnormal_somatic_nervous2.68784134
18MP0003787_abnormal_imprinting2.63453846
19MP0001486_abnormal_startle_reflex2.28677602
20MP0005646_abnormal_pituitary_gland2.27842515
21MP0002734_abnormal_mechanical_nocicepti2.26177534
22MP0002736_abnormal_nociception_after2.18804800
23MP0001529_abnormal_vocalization2.14280251
24MP0001440_abnormal_grooming_behavior2.13802271
25MP0002733_abnormal_thermal_nociception2.05370694
26MP0003123_paternal_imprinting1.94390981
27MP0005623_abnormal_meninges_morphology1.93919228
28MP0005386_behavior/neurological_phenoty1.92184974
29MP0004924_abnormal_behavior1.92184974
30MP0001970_abnormal_pain_threshold1.90253367
31MP0002067_abnormal_sensory_capabilities1.88613136
32MP0002557_abnormal_social/conspecific_i1.85425425
33MP0001905_abnormal_dopamine_level1.80972023
34MP0002909_abnormal_adrenal_gland1.76324302
35MP0002735_abnormal_chemical_nociception1.74781741
36MP0008438_abnormal_cutaneous_collagen1.73837961
37MP0004142_abnormal_muscle_tone1.73762545
38MP0003121_genomic_imprinting1.66003805
39MP0001984_abnormal_olfaction1.62460422
40MP0002184_abnormal_innervation1.54601105
41MP0004811_abnormal_neuron_physiology1.52079372
42MP0008569_lethality_at_weaning1.51182701
43MP0000751_myopathy1.48384011
44MP0001299_abnormal_eye_distance/1.44319634
45MP0001502_abnormal_circadian_rhythm1.38346365
46MP0003329_amyloid_beta_deposits1.38203597
47MP0002066_abnormal_motor_capabilities/c1.36944960
48MP0009780_abnormal_chondrocyte_physiolo1.32262264
49MP0003879_abnormal_hair_cell1.27590191
50MP0002882_abnormal_neuron_morphology1.23698265
51MP0000778_abnormal_nervous_system1.23081538
52MP0008877_abnormal_DNA_methylation1.21398268
53MP0000955_abnormal_spinal_cord1.19892507
54MP0004858_abnormal_nervous_system1.18500381
55MP0000013_abnormal_adipose_tissue1.17683474
56MP0008872_abnormal_physiological_respon1.16260312
57MP0003633_abnormal_nervous_system1.10030346
58MP0001188_hyperpigmentation1.05477853
59MP0005535_abnormal_body_temperature1.04119247
60MP0002837_dystrophic_cardiac_calcinosis1.03868562
61MP0005257_abnormal_intraocular_pressure1.01250871
62MP0002069_abnormal_eating/drinking_beha0.96961849
63MP0004885_abnormal_endolymph0.96085509
64MP0004272_abnormal_basement_membrane0.95389281
65MP0003646_muscle_fatigue0.94212250
66MP0003631_nervous_system_phenotype0.93350111
67MP0002152_abnormal_brain_morphology0.92228594
68MP0008874_decreased_physiological_sensi0.91296418
69MP0002229_neurodegeneration0.90744681
70MP0000631_abnormal_neuroendocrine_gland0.87677349
71MP0002295_abnormal_pulmonary_circulatio0.87347697
72MP0001346_abnormal_lacrimal_gland0.87046060
73MP0010386_abnormal_urinary_bladder0.86979366
74MP0000534_abnormal_ureter_morphology0.86704423
75MP0002638_abnormal_pupillary_reflex0.85633828
76MP0005551_abnormal_eye_electrophysiolog0.85502978
77MP0001958_emphysema0.85054753
78MP0004085_abnormal_heartbeat0.84154985
79MP0002876_abnormal_thyroid_physiology0.82369262
80MP0004145_abnormal_muscle_electrophysio0.81223785
81MP0003705_abnormal_hypodermis_morpholog0.79742692
82MP0005167_abnormal_blood-brain_barrier0.79672934
83MP0003690_abnormal_glial_cell0.79260291
84MP0004233_abnormal_muscle_weight0.79027504
85MP0003385_abnormal_body_wall0.77953233
86MP0001177_atelectasis0.77736152
87MP0003942_abnormal_urinary_system0.77684934
88MP0002249_abnormal_larynx_morphology0.77430071
89MP0005499_abnormal_olfactory_system0.76901733
90MP0005394_taste/olfaction_phenotype0.76901733
91MP0001348_abnormal_lacrimal_gland0.76563561
92MP0010030_abnormal_orbit_morphology0.74253407
93MP0003861_abnormal_nervous_system0.73221027
94MP0005503_abnormal_tendon_morphology0.73082068
95MP0008961_abnormal_basal_metabolism0.72836910
96MP0000566_synostosis0.71131405
97MP0005171_absent_coat_pigmentation0.71078880
98MP0002090_abnormal_vision0.71023212
99MP0001664_abnormal_digestion0.68097079
100MP0003634_abnormal_glial_cell0.66265408
101MP0002089_abnormal_postnatal_growth/wei0.65542762
102MP0000003_abnormal_adipose_tissue0.65418188
103MP0001963_abnormal_hearing_physiology0.64212739
104MP0003283_abnormal_digestive_organ0.62850273
105MP0003938_abnormal_ear_development0.62081466
106MP0003632_abnormal_nervous_system0.61781730
107MP0002752_abnormal_somatic_nervous0.61195852
108MP0004215_abnormal_myocardial_fiber0.60636672
109MP0000579_abnormal_nail_morphology0.60152613
110MP0001943_abnormal_respiration0.59769205
111MP0001270_distended_abdomen0.59589325
112MP0003172_abnormal_lysosome_physiology0.59072677
113MP0005448_abnormal_energy_balance0.58712716
114MP0003075_altered_response_to0.58693685
115MP0000569_abnormal_digit_pigmentation0.58161891
116MP0003137_abnormal_impulse_conducting0.57399692
117MP0004742_abnormal_vestibular_system0.56330998
118MP0000462_abnormal_digestive_system0.56007300
119MP0003279_aneurysm0.55581262
120MP0000639_abnormal_adrenal_gland0.55554007
121MP0010769_abnormal_survival0.54574173
122MP0000604_amyloidosis0.54439402
123MP0004043_abnormal_pH_regulation0.53718894
124MP0003956_abnormal_body_size0.50401605
125MP0004484_altered_response_of0.50391351
126MP0000920_abnormal_myelination0.50046317
127MP0006072_abnormal_retinal_apoptosis0.49075701
128MP0002332_abnormal_exercise_endurance0.48972415
129MP0000747_muscle_weakness0.48955858

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.76847507
2Myokymia (HP:0002411)6.55768770
3Focal seizures (HP:0007359)5.63553555
4Visual hallucinations (HP:0002367)5.05006750
5Atonic seizures (HP:0010819)4.93199691
6Epileptic encephalopathy (HP:0200134)4.42044336
7Absence seizures (HP:0002121)4.40848080
8Febrile seizures (HP:0002373)4.36243365
9Progressive cerebellar ataxia (HP:0002073)4.25171680
10Generalized tonic-clonic seizures (HP:0002069)4.01714927
11Dialeptic seizures (HP:0011146)3.94738824
12Polyphagia (HP:0002591)3.82546979
13Failure to thrive in infancy (HP:0001531)3.81209177
14Abnormal eating behavior (HP:0100738)3.72765287
15Pheochromocytoma (HP:0002666)3.61455006
16Anxiety (HP:0000739)3.40633666
17Abnormal hair whorl (HP:0010721)3.40124001
18Impaired vibration sensation in the lower limbs (HP:0002166)3.32072516
19Limb dystonia (HP:0002451)3.28622782
20Neuroendocrine neoplasm (HP:0100634)3.24643910
21Depression (HP:0000716)3.22645260
22Action tremor (HP:0002345)3.19877636
23Supranuclear gaze palsy (HP:0000605)3.05264275
24Oligomenorrhea (HP:0000876)3.04431592
25Ankle clonus (HP:0011448)3.03476240
26Truncal ataxia (HP:0002078)3.02412046
27Hyperventilation (HP:0002883)3.00906660
28Premature rupture of membranes (HP:0001788)2.97913582
29Dysdiadochokinesis (HP:0002075)2.96813960
30Broad-based gait (HP:0002136)2.95424897
31Neurofibrillary tangles (HP:0002185)2.94234703
32Postural instability (HP:0002172)2.94054738
33Menstrual irregularities (HP:0000858)2.86350603
34Progressive inability to walk (HP:0002505)2.85435712
35Dysmetria (HP:0001310)2.85369216
36Abnormality of the labia minora (HP:0012880)2.83748272
37Urinary bladder sphincter dysfunction (HP:0002839)2.82658660
38Hand muscle atrophy (HP:0009130)2.80996049
39Poor suck (HP:0002033)2.80685153
40Gaze-evoked nystagmus (HP:0000640)2.80128676
41Agitation (HP:0000713)2.75180990
42Poor eye contact (HP:0000817)2.71637516
43Upper limb amyotrophy (HP:0009129)2.68953165
44Distal upper limb amyotrophy (HP:0007149)2.68953165
45Insomnia (HP:0100785)2.66572376
46Hypoventilation (HP:0002791)2.64699337
47Impaired social interactions (HP:0000735)2.63164441
48Abnormal social behavior (HP:0012433)2.63164441
49Genetic anticipation (HP:0003743)2.58865264
50Protrusio acetabuli (HP:0003179)2.55235596
51Papilledema (HP:0001085)2.55220144
52Mutism (HP:0002300)2.54517917
53Cerebral hypomyelination (HP:0006808)2.53553707
54Abnormality of dentin (HP:0010299)2.51282155
55Bradykinesia (HP:0002067)2.50637274
56Torticollis (HP:0000473)2.49917994
57Cerebral inclusion bodies (HP:0100314)2.46176238
58Psychosis (HP:0000709)2.46100722
59Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.42153460
60Scanning speech (HP:0002168)2.42061467
61Amblyopia (HP:0000646)2.40096615
62Status epilepticus (HP:0002133)2.39011250
63Akinesia (HP:0002304)2.38963061
64Sleep apnea (HP:0010535)2.38235292
65Urinary urgency (HP:0000012)2.37349188
66Spastic gait (HP:0002064)2.37218985
67Focal dystonia (HP:0004373)2.35188051
68Specific learning disability (HP:0001328)2.34587144
69Nuclear cataract (HP:0100018)2.32968953
70Increased circulating renin level (HP:0000848)2.32868737
71Hyperthyroidism (HP:0000836)2.32635180
72Obstructive sleep apnea (HP:0002870)2.32435500
73Gait imbalance (HP:0002141)2.30889413
74Epileptiform EEG discharges (HP:0011182)2.30316088
75Narrow nasal bridge (HP:0000446)2.30174627
76Delusions (HP:0000746)2.28137654
77Hemiplegia (HP:0002301)2.26718772
78Ventricular fibrillation (HP:0001663)2.24930587
79Drooling (HP:0002307)2.23029095
80Excessive salivation (HP:0003781)2.23029095
81Impaired pain sensation (HP:0007328)2.22161878
82Abnormality of pain sensation (HP:0010832)2.22161878
83EEG with generalized epileptiform discharges (HP:0011198)2.21717291
84Intention tremor (HP:0002080)2.20908556
85Impaired smooth pursuit (HP:0007772)2.19554855
86Hypercortisolism (HP:0001578)2.19135011
87Shallow orbits (HP:0000586)2.18663969
88Tetraplegia (HP:0002445)2.18164484
89Esotropia (HP:0000565)2.17875189
90Craniofacial dystonia (HP:0012179)2.15827340
91Hypsarrhythmia (HP:0002521)2.14825502
92Diplopia (HP:0000651)2.14246568
93Abnormality of binocular vision (HP:0011514)2.14246568
94Abnormality of the lower motor neuron (HP:0002366)2.11984311
95Turricephaly (HP:0000262)2.11577845
96Generalized myoclonic seizures (HP:0002123)2.11294002
97Impaired vibratory sensation (HP:0002495)2.11011221
98Neoplasm of the peripheral nervous system (HP:0100007)2.10957579
99Cholecystitis (HP:0001082)2.10806866
100Abnormal gallbladder physiology (HP:0012438)2.10806866
101Abnormality of the corticospinal tract (HP:0002492)2.10686597
102Dysmetric saccades (HP:0000641)2.10393549
103Generalized hypotonia (HP:0001290)2.10137370
104Hemiparesis (HP:0001269)2.09331326
105Fetal akinesia sequence (HP:0001989)2.08903212
106Congenital primary aphakia (HP:0007707)2.07850149
107Abnormal EKG (HP:0003115)2.05254212
108Resting tremor (HP:0002322)2.04329387
109Lower limb muscle weakness (HP:0007340)2.03649025
110Abnormal mitochondria in muscle tissue (HP:0008316)1.98663824
111Hyperacusis (HP:0010780)1.96148516
112Growth hormone excess (HP:0000845)1.95511618
113Neuronal loss in central nervous system (HP:0002529)1.95048186
114Acute necrotizing encephalopathy (HP:0006965)1.93107634
115Annular pancreas (HP:0001734)1.92932573
116Abnormality of ocular smooth pursuit (HP:0000617)1.92490521
117Inability to walk (HP:0002540)1.92238004
118Medial flaring of the eyebrow (HP:0010747)1.91733077
119Nephrogenic diabetes insipidus (HP:0009806)1.88705703
120Rigidity (HP:0002063)1.88257129
121Clonus (HP:0002169)1.87892279
122Blue irides (HP:0000635)1.87475563
123Hypothermia (HP:0002045)1.85829356
124Apathy (HP:0000741)1.84311875
125Abnormality of saccadic eye movements (HP:0000570)1.83877168
126Hammertoe (HP:0001765)1.83383187
127Termporal pattern (HP:0011008)1.83025897
128Heterochromia iridis (HP:0001100)1.82394356
129Bowel diverticulosis (HP:0005222)1.80998539
130Mild short stature (HP:0003502)1.80245376
131Aplasia involving bones of the extremities (HP:0009825)1.79166459
132Aplasia involving bones of the upper limbs (HP:0009823)1.79166459
133Aplasia of the phalanges of the hand (HP:0009802)1.79166459
134Alacrima (HP:0000522)1.78252421
135Bladder diverticulum (HP:0000015)1.77544604
136Lower limb amyotrophy (HP:0007210)1.75879467
137Cerebral aneurysm (HP:0004944)1.71443512
138Peripheral hypomyelination (HP:0007182)1.71315295
139Congenital malformation of the right heart (HP:0011723)1.68528947
140Double outlet right ventricle (HP:0001719)1.68528947
141Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.67581426
142Diminished movement (HP:0002374)1.67010905
143Hypokinesia (HP:0002375)1.67003183
144Overriding aorta (HP:0002623)1.66535087
145Bronchomalacia (HP:0002780)1.60727178
146Diminished motivation (HP:0000745)1.60675893
147Renal duplication (HP:0000075)1.60320329
148Hydroureter (HP:0000072)1.60093014
149Spastic tetraparesis (HP:0001285)1.57303527

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK35.21750645
2MAP3K124.18083834
3MAP3K43.63837478
4MAP3K93.63671742
5EPHA43.05097187
6MAP2K72.95338436
7MINK12.52026618
8MAP2K42.39839795
9TESK12.36774021
10LIMK12.30890684
11NTRK22.26027753
12CASK2.16817356
13ARAF2.08926188
14MARK11.98910338
15CDK191.97829556
16PAK61.89398748
17KSR21.68133281
18DAPK21.66565426
19PLK21.59260906
20GRK51.58322335
21PNCK1.56797890
22CDK51.46181021
23DAPK11.45995375
24UHMK11.40706625
25FES1.36838729
26NTRK11.36611379
27GRK71.35420976
28BRSK11.34424416
29KSR11.31607263
30PRKCG1.29862392
31CAMKK11.27439874
32TNIK1.26723572
33TNK21.23235011
34CAMK2A1.22891686
35WNK31.20667428
36ICK1.19833257
37MAPK131.19044719
38PRKD31.19031158
39STK381.18032352
40RIPK41.17502887
41MAP3K131.16978187
42OXSR11.16667071
43PTK21.16221752
44PDGFRA1.08634330
45RIPK11.07833565
46CDK180.98616793
47AKT30.98149219
48NEK10.94729084
49CDK140.94228930
50CDK150.93906899
51PAK30.91923094
52SGK2230.91734840
53SGK4940.91734840
54CAMKK20.91179016
55PRKCH0.89333818
56CAMK10.86702842
57TAOK10.86383090
58ROCK20.85861484
59TRIB30.85723234
60CAMK2B0.85357884
61CSNK1A1L0.83749952
62CDK11A0.80850933
63FGFR20.79794748
64CAMK2G0.79483277
65SGK20.78684460
66LATS20.78183153
67SIK30.77929056
68PRPF4B0.76920870
69MAP2K60.76330827
70SIK20.76074288
71CSNK1G20.75327972
72NME10.73289043
73TSSK60.73165878
74MAP3K20.72252778
75MAP3K10.70949763
76TYRO30.70167936
77PHKG10.68601048
78PHKG20.68601048
79STK110.67957757
80BRAF0.67421009
81DDR20.66154339
82SGK10.65453611
83LMTK20.64256871
84NEK60.63842215
85SGK30.63686346
86PINK10.63558432
87MAPKAPK50.63071897
88CSNK1G10.62010693
89ALK0.61583990
90CAMK2D0.61132249
91RAF10.60520672
92ADRBK20.59433812
93ADRBK10.55519118
94PDK10.54522993
95PDPK10.54440499
96FER0.53400307
97RET0.52931011
98ROCK10.52114218
99PAK20.50401722
100BCR0.49926883
101PRKCE0.49088073
102PDK40.48020434
103PDK30.48020434
104PKN10.47548315
105RPS6KA30.47466943
106EPHA20.46583935
107CAMK1G0.43617105
108PKN20.43244304
109DYRK1A0.42591292
110WNK10.42503181
111MARK20.42129037
112CCNB10.42045009
113CSNK1G30.41058384
114BMPR20.40887819
115PRKD20.39957427
116MAPK100.38808915
117CDC42BPA0.38498909
118DAPK30.38348554
119RPS6KA20.38291447
120PTK2B0.38147570
121MET0.38103345
122PRKCZ0.37751205
123PRKACA0.37252147
124PAK40.37169632
125MYLK0.36233052
126ERBB40.34953873
127PDK20.34909749
128DYRK20.33025125
129SIK10.31661133
130MAP4K20.31621854
131CSNK1A10.30886230
132AKT20.30754760
133PRKCI0.30191539
134CSNK1D0.29440427
135PRKG20.29242530

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.08852458
2Synaptic vesicle cycle_Homo sapiens_hsa047214.00656404
3GABAergic synapse_Homo sapiens_hsa047273.12623186
4Collecting duct acid secretion_Homo sapiens_hsa049662.73632568
5Olfactory transduction_Homo sapiens_hsa047402.68202700
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.66417423
7Morphine addiction_Homo sapiens_hsa050322.62858216
8Circadian entrainment_Homo sapiens_hsa047132.53278028
9Amphetamine addiction_Homo sapiens_hsa050312.49232392
10Glutamatergic synapse_Homo sapiens_hsa047242.28312246
11Dopaminergic synapse_Homo sapiens_hsa047282.21897119
12Long-term potentiation_Homo sapiens_hsa047202.19981332
13Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.16136626
14Cocaine addiction_Homo sapiens_hsa050302.12834142
15Salivary secretion_Homo sapiens_hsa049702.00903001
16Serotonergic synapse_Homo sapiens_hsa047261.95729623
17Insulin secretion_Homo sapiens_hsa049111.93482123
18Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.92498023
19Taste transduction_Homo sapiens_hsa047421.90144353
20Vibrio cholerae infection_Homo sapiens_hsa051101.87468899
21Gastric acid secretion_Homo sapiens_hsa049711.67402065
22Cholinergic synapse_Homo sapiens_hsa047251.67091589
23Long-term depression_Homo sapiens_hsa047301.61001021
24Renin secretion_Homo sapiens_hsa049241.58880231
25Oxidative phosphorylation_Homo sapiens_hsa001901.57593257
26Aldosterone synthesis and secretion_Homo sapiens_hsa049251.53838349
27Calcium signaling pathway_Homo sapiens_hsa040201.42663530
28Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.41099881
29Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.39443454
30Oxytocin signaling pathway_Homo sapiens_hsa049211.34188191
31Parkinsons disease_Homo sapiens_hsa050121.32353676
32Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.29722668
33Cardiac muscle contraction_Homo sapiens_hsa042601.27181764
34Gap junction_Homo sapiens_hsa045401.26028461
35Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.25070640
36Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.20317772
37GnRH signaling pathway_Homo sapiens_hsa049121.19234148
38Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.16018667
39Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.10831359
40cAMP signaling pathway_Homo sapiens_hsa040241.08932279
41Type I diabetes mellitus_Homo sapiens_hsa049401.08498873
42Alzheimers disease_Homo sapiens_hsa050101.01425892
43Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.00112154
44Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.96127552
45Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.95275023
46Estrogen signaling pathway_Homo sapiens_hsa049150.95153581
47Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.94638570
48Type II diabetes mellitus_Homo sapiens_hsa049300.93242343
49Melanogenesis_Homo sapiens_hsa049160.86644022
50Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.82301478
51Arginine and proline metabolism_Homo sapiens_hsa003300.80970060
52Phosphatidylinositol signaling system_Homo sapiens_hsa040700.78451546
53Hippo signaling pathway_Homo sapiens_hsa043900.78398068
54Fatty acid elongation_Homo sapiens_hsa000620.78066057
55Vascular smooth muscle contraction_Homo sapiens_hsa042700.77923709
56Huntingtons disease_Homo sapiens_hsa050160.77030710
57Biosynthesis of amino acids_Homo sapiens_hsa012300.76210740
58Phototransduction_Homo sapiens_hsa047440.75602782
59Thyroid hormone synthesis_Homo sapiens_hsa049180.74101262
60cGMP-PKG signaling pathway_Homo sapiens_hsa040220.73456434
61ErbB signaling pathway_Homo sapiens_hsa040120.72924001
62Oocyte meiosis_Homo sapiens_hsa041140.70400476
63Axon guidance_Homo sapiens_hsa043600.68775781
64Rheumatoid arthritis_Homo sapiens_hsa053230.67724389
65Dilated cardiomyopathy_Homo sapiens_hsa054140.66212659
66Wnt signaling pathway_Homo sapiens_hsa043100.64755308
67Alcoholism_Homo sapiens_hsa050340.63195661
68Glioma_Homo sapiens_hsa052140.60249356
69Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.60205552
70MAPK signaling pathway_Homo sapiens_hsa040100.59044026
71Butanoate metabolism_Homo sapiens_hsa006500.58501291
72Pancreatic secretion_Homo sapiens_hsa049720.58228399
73Carbon metabolism_Homo sapiens_hsa012000.57052284
74Circadian rhythm_Homo sapiens_hsa047100.57012207
75Glycosaminoglycan degradation_Homo sapiens_hsa005310.56788682
76N-Glycan biosynthesis_Homo sapiens_hsa005100.56230501
77Dorso-ventral axis formation_Homo sapiens_hsa043200.55875194
78ECM-receptor interaction_Homo sapiens_hsa045120.55542838
79Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.54024152
80Tight junction_Homo sapiens_hsa045300.53759904
81Prion diseases_Homo sapiens_hsa050200.53169036
82Glucagon signaling pathway_Homo sapiens_hsa049220.51708218
83Phospholipase D signaling pathway_Homo sapiens_hsa040720.51687433
84Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.51644923
85Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.50540748
86Central carbon metabolism in cancer_Homo sapiens_hsa052300.47927019
87Bile secretion_Homo sapiens_hsa049760.47804764
88Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.47220339
89Fatty acid metabolism_Homo sapiens_hsa012120.46642560
90AMPK signaling pathway_Homo sapiens_hsa041520.46425373
91Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.46404723
92Hedgehog signaling pathway_Homo sapiens_hsa043400.45563837
93Folate biosynthesis_Homo sapiens_hsa007900.44447855
94Focal adhesion_Homo sapiens_hsa045100.44329738
95Arginine biosynthesis_Homo sapiens_hsa002200.43717256
96Nitrogen metabolism_Homo sapiens_hsa009100.43183697
97Phagosome_Homo sapiens_hsa041450.42315274
98Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.42011036
99Ras signaling pathway_Homo sapiens_hsa040140.41796819
100Steroid biosynthesis_Homo sapiens_hsa001000.40692449
101Ovarian steroidogenesis_Homo sapiens_hsa049130.40443947
102Choline metabolism in cancer_Homo sapiens_hsa052310.39873199
1032-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.38827695
104Protein digestion and absorption_Homo sapiens_hsa049740.38544316
105Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.38528631
106Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.37016492
107SNARE interactions in vesicular transport_Homo sapiens_hsa041300.34365768
108Pyruvate metabolism_Homo sapiens_hsa006200.34228454
109Neurotrophin signaling pathway_Homo sapiens_hsa047220.33662154
110Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.31687603
111Insulin signaling pathway_Homo sapiens_hsa049100.30062095
112Inositol phosphate metabolism_Homo sapiens_hsa005620.27751148
113Endocytosis_Homo sapiens_hsa041440.27060271
114Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.26603932
115Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.26149715
116Phenylalanine metabolism_Homo sapiens_hsa003600.26065158
117Rap1 signaling pathway_Homo sapiens_hsa040150.23854624
118Thyroid hormone signaling pathway_Homo sapiens_hsa049190.22621757
119Glycerophospholipid metabolism_Homo sapiens_hsa005640.22469337
120Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.22051863
121Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.21110705
122Carbohydrate digestion and absorption_Homo sapiens_hsa049730.20739505
123Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.20599894
124Vitamin B6 metabolism_Homo sapiens_hsa007500.19017050
125Sphingolipid signaling pathway_Homo sapiens_hsa040710.16996605

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