NSMCE1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)5.64076790
2viral transcription (GO:0019083)5.39357765
3DNA deamination (GO:0045006)5.32519103
4translational termination (GO:0006415)5.21990209
5ribosomal small subunit biogenesis (GO:0042274)5.17668965
6protein complex biogenesis (GO:0070271)4.79155491
7SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.72338543
8telomere maintenance via semi-conservative replication (GO:0032201)4.67525000
9cotranslational protein targeting to membrane (GO:0006613)4.65147803
10maturation of SSU-rRNA (GO:0030490)4.65035274
11translational elongation (GO:0006414)4.61288498
12protein targeting to ER (GO:0045047)4.59826450
13DNA strand elongation involved in DNA replication (GO:0006271)4.55429048
14respiratory electron transport chain (GO:0022904)4.49494317
15mitochondrial respiratory chain complex assembly (GO:0033108)4.44716392
16mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.44599370
17electron transport chain (GO:0022900)4.43191855
18proteasome assembly (GO:0043248)4.38407344
19protein localization to endoplasmic reticulum (GO:0070972)4.37659796
20establishment of protein localization to endoplasmic reticulum (GO:0072599)4.35456894
21mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.34427260
22mitochondrial respiratory chain complex I assembly (GO:0032981)4.34427260
23NADH dehydrogenase complex assembly (GO:0010257)4.34427260
24DNA strand elongation (GO:0022616)4.34123793
25translational initiation (GO:0006413)4.30139046
26telomere maintenance via recombination (GO:0000722)4.27836715
27negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.23469220
28chaperone-mediated protein transport (GO:0072321)4.20959801
29ribosomal large subunit biogenesis (GO:0042273)4.19564253
30cellular protein complex disassembly (GO:0043624)4.12440517
31nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.11864542
32viral life cycle (GO:0019058)4.11627733
33regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.98076457
34positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.94587746
35formation of translation preinitiation complex (GO:0001731)3.92939624
36anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.92518471
37negative regulation of ligase activity (GO:0051352)3.91520604
38negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.91520604
39mitotic recombination (GO:0006312)3.89353512
40pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.77000618
41DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.76246829
42respiratory chain complex IV assembly (GO:0008535)3.74947306
43translation (GO:0006412)3.73704646
44protein neddylation (GO:0045116)3.72928006
45DNA replication initiation (GO:0006270)3.70682322
46nucleotide-excision repair, DNA gap filling (GO:0006297)3.70265830
47signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.70181982
48intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.70181982
49signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.68431109
50signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.68431109
51signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.68431109
52deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.66317470
53ribonucleoprotein complex biogenesis (GO:0022613)3.66134373
54cytochrome complex assembly (GO:0017004)3.63259408
55antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.63000205
56establishment of protein localization to mitochondrial membrane (GO:0090151)3.62860159
57base-excision repair, AP site formation (GO:0006285)3.61482466
58protein complex disassembly (GO:0043241)3.61129865
59regulation of cellular amino acid metabolic process (GO:0006521)3.60422356
60signal transduction involved in DNA integrity checkpoint (GO:0072401)3.59918446
61signal transduction involved in DNA damage checkpoint (GO:0072422)3.59918446
62signal transduction involved in cell cycle checkpoint (GO:0072395)3.56335391
63DNA replication checkpoint (GO:0000076)3.55667035
64telomere maintenance via telomere lengthening (GO:0010833)3.50845558
65CENP-A containing nucleosome assembly (GO:0034080)3.50434909
66tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.44203150
67RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.44203150
68transcription elongation from RNA polymerase III promoter (GO:0006385)3.41985960
69termination of RNA polymerase III transcription (GO:0006386)3.41985960
70macromolecular complex disassembly (GO:0032984)3.41688379
71antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.40761819
72positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.39248112
73rRNA processing (GO:0006364)3.37940667
74mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.36574870
75chromatin remodeling at centromere (GO:0031055)3.34843708
76deoxyribonucleotide catabolic process (GO:0009264)3.30637523
77exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.29313276
78transcription-coupled nucleotide-excision repair (GO:0006283)3.29035442
79regulation of mitochondrial translation (GO:0070129)3.28663239
80nuclear-transcribed mRNA catabolic process (GO:0000956)3.26579394
81positive regulation of ligase activity (GO:0051351)3.26333929
82rRNA metabolic process (GO:0016072)3.26306526
83spliceosomal snRNP assembly (GO:0000387)3.26239234
84nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.24881086
85deoxyribose phosphate catabolic process (GO:0046386)3.24019374
86ATP synthesis coupled proton transport (GO:0015986)3.21395584
87energy coupled proton transport, down electrochemical gradient (GO:0015985)3.21395584
88cullin deneddylation (GO:0010388)3.18595765
89purine deoxyribonucleotide catabolic process (GO:0009155)3.15579531
90oxidative phosphorylation (GO:0006119)3.15256910
91protein deneddylation (GO:0000338)3.13335420
92pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.11756175
93protein-cofactor linkage (GO:0018065)3.11616005
94DNA replication-independent nucleosome assembly (GO:0006336)3.11163893
95DNA replication-independent nucleosome organization (GO:0034724)3.11163893
96ATP biosynthetic process (GO:0006754)3.10252017
97viral mRNA export from host cell nucleus (GO:0046784)3.09808467
98regulation of ubiquitin-protein transferase activity (GO:0051438)3.09474037
99mRNA catabolic process (GO:0006402)3.09472940
1007-methylguanosine mRNA capping (GO:0006370)3.08641294
101preassembly of GPI anchor in ER membrane (GO:0016254)3.08390988
102GTP biosynthetic process (GO:0006183)3.08060727
103hydrogen ion transmembrane transport (GO:1902600)3.05747543
104purine nucleoside triphosphate biosynthetic process (GO:0009145)3.04670591
105purine nucleobase biosynthetic process (GO:0009113)3.03914268
106regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.03706615
107cell cycle G1/S phase transition (GO:0044843)3.03625119
108G1/S transition of mitotic cell cycle (GO:0000082)3.03625119
109cellular component biogenesis (GO:0044085)3.03507922
110purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.02498243
1117-methylguanosine RNA capping (GO:0009452)3.02326076
112RNA capping (GO:0036260)3.02326076
113guanosine-containing compound biosynthetic process (GO:1901070)3.02213897
114pyrimidine nucleotide catabolic process (GO:0006244)3.00681385
115regulation of ligase activity (GO:0051340)2.99913602
116nucleobase biosynthetic process (GO:0046112)2.98776932
117DNA damage response, signal transduction by p53 class mediator (GO:0030330)2.98654021
118histone exchange (GO:0043486)2.98624116
119positive regulation of cell cycle arrest (GO:0071158)2.97362681
120protein targeting to membrane (GO:0006612)2.97296335
121RNA catabolic process (GO:0006401)2.96525163
122attachment of spindle microtubules to kinetochore (GO:0008608)2.95922748
123mannosylation (GO:0097502)2.94079132
124ribosome biogenesis (GO:0042254)2.93065484
125mitotic metaphase plate congression (GO:0007080)2.92779737
126protein localization to kinetochore (GO:0034501)2.90956716
1272-deoxyribonucleotide metabolic process (GO:0009394)2.90246549
128deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.90232894
129rRNA modification (GO:0000154)2.88688603
130L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.86909608
131UTP biosynthetic process (GO:0006228)2.85858390
132GPI anchor biosynthetic process (GO:0006506)2.85131629
133DNA replication-dependent nucleosome assembly (GO:0006335)2.84795453
134DNA replication-dependent nucleosome organization (GO:0034723)2.84795453
135proton transport (GO:0015992)2.84371432
136protein targeting to mitochondrion (GO:0006626)2.83728529
137hydrogen transport (GO:0006818)2.82543722
138adenosine metabolic process (GO:0046085)2.81462496
139deoxyribose phosphate metabolic process (GO:0019692)2.81203139
140mast cell activation (GO:0045576)2.80958886
141spliceosomal complex assembly (GO:0000245)2.80951742
142cytidine deamination (GO:0009972)2.79482387
143cytidine metabolic process (GO:0046087)2.79482387
144cytidine catabolic process (GO:0006216)2.79482387
145aldehyde catabolic process (GO:0046185)2.78513535
146regulation of memory T cell differentiation (GO:0043380)2.77799416
147purine deoxyribonucleotide metabolic process (GO:0009151)2.72769978
148response to interferon-beta (GO:0035456)2.72545790

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.00565733
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.05518128
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.80700940
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.78931981
5GABP_17652178_ChIP-ChIP_JURKAT_Human3.76642392
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.67333786
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.50850459
8SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.31024857
9ETS1_20019798_ChIP-Seq_JURKAT_Human3.28619586
10NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.07460617
11CREB1_15753290_ChIP-ChIP_HEK293T_Human3.04406836
12E2F4_17652178_ChIP-ChIP_JURKAT_Human2.98967879
13MYC_18358816_ChIP-ChIP_MESCs_Mouse2.95020016
14MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.91148226
15ELF1_17652178_ChIP-ChIP_JURKAT_Human2.86252109
16FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.76891459
17HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.76375533
18MYC_19079543_ChIP-ChIP_MESCs_Mouse2.70310941
19MYC_19030024_ChIP-ChIP_MESCs_Mouse2.68090332
20CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.61328714
21FOXM1_23109430_ChIP-Seq_U2OS_Human2.61321501
22VDR_23849224_ChIP-Seq_CD4+_Human2.60176462
23IRF8_22096565_ChIP-ChIP_GC-B_Human2.59372272
24CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.52677549
25XRN2_22483619_ChIP-Seq_HELA_Human2.42510636
26* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.37373589
27DCP1A_22483619_ChIP-Seq_HELA_Human2.23169326
28FOXP3_21729870_ChIP-Seq_TREG_Human2.21074216
29E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.16974917
30* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.15465716
31SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.14350648
32NELFA_20434984_ChIP-Seq_ESCs_Mouse2.11184557
33* GABP_19822575_ChIP-Seq_HepG2_Human2.02044652
34* SRF_21415370_ChIP-Seq_HL-1_Mouse1.97785493
35TTF2_22483619_ChIP-Seq_HELA_Human1.96427415
36CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.90544759
37FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.85839431
38THAP11_20581084_ChIP-Seq_MESCs_Mouse1.83872386
39ELK1_19687146_ChIP-ChIP_HELA_Human1.80441638
40* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.80104313
41* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.78004845
42YY1_21170310_ChIP-Seq_MESCs_Mouse1.77907768
43HOXB4_20404135_ChIP-ChIP_EML_Mouse1.77787107
44MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.70971111
45PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.67806794
46PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.67296122
47ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.63823382
48AR_21909140_ChIP-Seq_LNCAP_Human1.60344752
49POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.59066209
50SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.56035463
51CIITA_25753668_ChIP-Seq_RAJI_Human1.55038630
52MYCN_18555785_ChIP-Seq_MESCs_Mouse1.54301777
53ERG_20887958_ChIP-Seq_HPC-7_Mouse1.52531875
54CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.42883802
55MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.42878771
56NANOG_18555785_ChIP-Seq_MESCs_Mouse1.40661110
57E2F1_21310950_ChIP-Seq_MCF-7_Human1.40454796
58IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.37673935
59ZFX_18555785_ChIP-Seq_MESCs_Mouse1.35920055
60IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.35730892
61SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.34518877
62KDM5A_27292631_Chip-Seq_BREAST_Human1.28184776
63EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.27833547
64TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.27437575
65YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.26993926
66CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.26924206
67NOTCH1_21737748_ChIP-Seq_TLL_Human1.23058530
68* ELK1_22589737_ChIP-Seq_MCF10A_Human1.22081699
69SPI1_23547873_ChIP-Seq_NB4_Human1.20195660
70HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.18552258
71BP1_19119308_ChIP-ChIP_Hs578T_Human1.18366103
72ZNF274_21170338_ChIP-Seq_K562_Hela1.18025727
73IRF1_19129219_ChIP-ChIP_H3396_Human1.14640260
74HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.14414437
75PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.13886979
76ELF1_20517297_ChIP-Seq_JURKAT_Human1.13747279
77ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.12243778
78POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.12173641
79CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.11864969
80ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.08205129
81MYC_18940864_ChIP-ChIP_HL60_Human1.07777314
82PADI4_21655091_ChIP-ChIP_MCF-7_Human1.06915245
83EGR1_23403033_ChIP-Seq_LIVER_Mouse1.06128960
84BCL6_27268052_Chip-Seq_Bcells_Human1.06005650
85FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.05914195
86E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.04724359
87BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.02640761
88RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.02246852
89PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.01864457
90CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.00252448
91GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.00066724
92EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.99039492
93TP53_22573176_ChIP-Seq_HFKS_Human0.98567890
94CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.98498894
95HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.96795524
96KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.96722190
97* MYB_26560356_Chip-Seq_TH2_Human0.96626307
98* LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.96412245
99GATA3_26560356_Chip-Seq_TH2_Human0.95807630
100AR_20517297_ChIP-Seq_VCAP_Human0.94831448
101MYC_22102868_ChIP-Seq_BL_Human0.93801529
102DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.93060328
103YY1_22570637_ChIP-Seq_MALME-3M_Human0.92475672
104CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.92246243
105KLF4_18555785_ChIP-Seq_MESCs_Mouse0.90678203
106* STAT4_19710469_ChIP-ChIP_TH1__Mouse0.90504881
107NANOG_20526341_ChIP-Seq_ESCs_Human0.89763063
108STAT3_1855785_ChIP-Seq_MESCs_Mouse0.89460323
109* STAT1_20625510_ChIP-Seq_HELA_Human0.89376967
110CTCF_18555785_ChIP-Seq_MESCs_Mouse0.88805711
111ERG_20517297_ChIP-Seq_VCAP_Human0.88364801
112VDR_21846776_ChIP-Seq_THP-1_Human0.88282309
113P300_27268052_Chip-Seq_Bcells_Human0.87881114
114TFEB_21752829_ChIP-Seq_HELA_Human0.86356891
115* RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.85967605
116* PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.84281529
117* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.84052755
118DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.82509041
119* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.80454108
120KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.80268077
121E2F1_20622854_ChIP-Seq_HELA_Human0.80074040
122TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.76351262
123SOX2_18555785_ChIP-Seq_MESCs_Mouse0.76108066
124SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.75109965
125* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.72443536
126GATA1_22383799_ChIP-Seq_G1ME_Mouse0.71865924
127IRF8_21731497_ChIP-ChIP_J774_Mouse0.71003067
128CTCF_26484167_Chip-Seq_Bcells_Mouse0.70769741
129* TBX5_21415370_ChIP-Seq_HL-1_Mouse0.66833436
130CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.66398337

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.27761993
2MP0010094_abnormal_chromosome_stability3.84704294
3MP0004957_abnormal_blastocyst_morpholog3.82065444
4MP0003111_abnormal_nucleus_morphology3.50492773
5MP0003077_abnormal_cell_cycle3.38031844
6MP0008057_abnormal_DNA_replication3.23990069
7MP0008058_abnormal_DNA_repair3.11585372
8MP0009379_abnormal_foot_pigmentation2.70239267
9MP0008007_abnormal_cellular_replicative2.67477812
10MP0008932_abnormal_embryonic_tissue2.39085642
11MP0001835_abnormal_antigen_presentation2.33754977
12MP0002396_abnormal_hematopoietic_system2.30414785
13MP0003763_abnormal_thymus_physiology2.16388963
14MP0008875_abnormal_xenobiotic_pharmacok2.11282330
15MP0003011_delayed_dark_adaptation2.08900790
16MP0005410_abnormal_fertilization2.07417793
17MP0003786_premature_aging2.05803516
18MP0009333_abnormal_splenocyte_physiolog2.03787471
19MP0003195_calcinosis1.97378530
20MP0000685_abnormal_immune_system1.97186915
21MP0003718_maternal_effect1.94483563
22MP0000490_abnormal_crypts_of1.83226721
23MP0002837_dystrophic_cardiac_calcinosis1.80396749
24MP0005377_hearing/vestibular/ear_phenot1.79958212
25MP0003878_abnormal_ear_physiology1.79958212
26MP0008877_abnormal_DNA_methylation1.79517861
27MP0009764_decreased_sensitivity_to1.73859597
28MP0005671_abnormal_response_to1.70379997
29MP0008995_early_reproductive_senescence1.70079941
30MP0006072_abnormal_retinal_apoptosis1.67665621
31MP0002132_abnormal_respiratory_system1.60408897
32MP0002876_abnormal_thyroid_physiology1.60403624
33MP0002398_abnormal_bone_marrow1.55635876
34MP0003186_abnormal_redox_activity1.54157407
35MP0001929_abnormal_gametogenesis1.54060530
36MP0001853_heart_inflammation1.50061861
37MP0002210_abnormal_sex_determination1.49954468
38MP0001730_embryonic_growth_arrest1.48595017
39MP0003315_abnormal_perineum_morphology1.47218965
40MP0000350_abnormal_cell_proliferation1.41806604
41MP0009785_altered_susceptibility_to1.39294983
42MP0002722_abnormal_immune_system1.38296472
43MP0003724_increased_susceptibility_to1.38134262
44MP0001800_abnormal_humoral_immune1.37316908
45MP0002148_abnormal_hypersensitivity_rea1.36728271
46MP0005084_abnormal_gallbladder_morpholo1.36701880
47MP0000703_abnormal_thymus_morphology1.36174066
48MP0003806_abnormal_nucleotide_metabolis1.35746267
49MP0006036_abnormal_mitochondrial_physio1.32979193
50MP0000313_abnormal_cell_death1.32969400
51MP0003436_decreased_susceptibility_to1.32678932
52MP0000689_abnormal_spleen_morphology1.32454534
53MP0002429_abnormal_blood_cell1.31282631
54MP0002019_abnormal_tumor_incidence1.30862327
55MP0002420_abnormal_adaptive_immunity1.29916570
56MP0000716_abnormal_immune_system1.28948771
57MP0001545_abnormal_hematopoietic_system1.28455167
58MP0005397_hematopoietic_system_phenotyp1.28455167
59MP0001873_stomach_inflammation1.28450701
60MP0001819_abnormal_immune_cell1.28215338
61MP0001968_abnormal_touch/_nociception1.27335597
62MP0001145_abnormal_male_reproductive1.24699410
63MP0002452_abnormal_antigen_presenting1.24414565
64MP0001905_abnormal_dopamine_level1.24115650
65MP0005379_endocrine/exocrine_gland_phen1.23258139
66MP0004808_abnormal_hematopoietic_stem1.21627551
67MP0002736_abnormal_nociception_after1.21128500
68MP0002160_abnormal_reproductive_system1.20504643
69MP0001986_abnormal_taste_sensitivity1.20224356
70MP0002405_respiratory_system_inflammati1.19302253
71MP0005551_abnormal_eye_electrophysiolog1.19301767
72MP0002163_abnormal_gland_morphology1.17898001
73MP0002723_abnormal_immune_serum1.17688608
74MP0005025_abnormal_response_to1.16404228
75MP0008872_abnormal_physiological_respon1.16084939
76MP0003567_abnormal_fetal_cardiomyocyte1.14418075
77MP0005075_abnormal_melanosome_morpholog1.13046744
78MP0005000_abnormal_immune_tolerance1.09211852
79MP0008469_abnormal_protein_level1.08337210
80MP0000653_abnormal_sex_gland1.07476890
81MP0004147_increased_porphyrin_level1.05117691
82MP0003698_abnormal_male_reproductive1.03448905
83MP0002080_prenatal_lethality1.02407671
84MP0002095_abnormal_skin_pigmentation1.02065277
85MP0001697_abnormal_embryo_size1.01908350
86MP0001529_abnormal_vocalization1.01495371
87MP0002638_abnormal_pupillary_reflex0.98689191
88MP0005253_abnormal_eye_physiology0.97889044
89MP0005636_abnormal_mineral_homeostasis0.97836046
90MP0006054_spinal_hemorrhage0.97737037
91MP0001919_abnormal_reproductive_system0.97319617
92MP0005389_reproductive_system_phenotype0.96132455
93MP0009765_abnormal_xenobiotic_induced0.96113201
94MP0001501_abnormal_sleep_pattern0.95837399
95MP0005319_abnormal_enzyme/_coenzyme0.94604062
96MP0005332_abnormal_amino_acid0.94225915
97MP0003252_abnormal_bile_duct0.92918026
98MP0000358_abnormal_cell_content/0.91223885
99MP0000015_abnormal_ear_pigmentation0.88722199
100MP0001764_abnormal_homeostasis0.87853645
101MP0003638_abnormal_response/metabolism_0.86595988
102MP0002234_abnormal_pharynx_morphology0.85000502
103MP0004043_abnormal_pH_regulation0.84814404
104MP0005360_urolithiasis0.84752755
105MP0005387_immune_system_phenotype0.84677687
106MP0001790_abnormal_immune_system0.84677687
107MP0005408_hypopigmentation0.83940078
108MP0008789_abnormal_olfactory_epithelium0.83602645
109MP0008260_abnormal_autophagy0.83453210
110MP0001533_abnormal_skeleton_physiology0.83222188
111MP0003136_yellow_coat_color0.83023840
112MP0004142_abnormal_muscle_tone0.82837474
113MP0009697_abnormal_copulation0.82075752
114MP0001672_abnormal_embryogenesis/_devel0.81448826
115MP0005380_embryogenesis_phenotype0.81448826
116MP0003866_abnormal_defecation0.80763916
117MP0000372_irregular_coat_pigmentation0.80729334
118MP0002938_white_spotting0.79620783
119MP0000858_altered_metastatic_potential0.79313776
120MP0002102_abnormal_ear_morphology0.78649429
121MP0005646_abnormal_pituitary_gland0.78187514
122MP0006292_abnormal_olfactory_placode0.77763518
123MP0009763_increased_sensitivity_to0.77079608
124MP0005645_abnormal_hypothalamus_physiol0.77058064
125MP0005464_abnormal_platelet_physiology0.76908645
126MP0006035_abnormal_mitochondrial_morpho0.76598757
127MP0002277_abnormal_respiratory_mucosa0.75695807
128MP0004145_abnormal_muscle_electrophysio0.75524377
129MP0003984_embryonic_growth_retardation0.74722523
130MP0001119_abnormal_female_reproductive0.74472577
131MP0010155_abnormal_intestine_physiology0.73646821
132MP0003221_abnormal_cardiomyocyte_apopto0.71413445
133MP0002088_abnormal_embryonic_growth/wei0.70988165
134MP0002085_abnormal_embryonic_tissue0.70666902
135MP0002419_abnormal_innate_immunity0.69895161
136MP0003656_abnormal_erythrocyte_physiolo0.68522662
137MP0005174_abnormal_tail_pigmentation0.68166125
138MP0001727_abnormal_embryo_implantation0.66212687
139MP0001845_abnormal_inflammatory_respons0.66099223
140MP0002161_abnormal_fertility/fecundity0.65697650
141MP0003646_muscle_fatigue0.63882039
142MP0001348_abnormal_lacrimal_gland0.62371081

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)5.59663868
2Abnormal number of erythroid precursors (HP:0012131)5.32170399
3Reticulocytopenia (HP:0001896)4.93538187
4Macrocytic anemia (HP:0001972)3.74417510
5Hepatocellular necrosis (HP:0001404)3.51392143
6Pallor (HP:0000980)3.48221776
7Acute necrotizing encephalopathy (HP:0006965)3.47919413
8Aplastic anemia (HP:0001915)3.45205443
9Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.44848914
10Decreased activity of mitochondrial respiratory chain (HP:0008972)3.44848914
11Mitochondrial inheritance (HP:0001427)3.41443719
12Birth length less than 3rd percentile (HP:0003561)3.38575845
13Cerebral edema (HP:0002181)3.32086091
14Hepatic necrosis (HP:0002605)3.27812947
15Abnormal mitochondria in muscle tissue (HP:0008316)3.19822688
16Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.09976585
17Severe combined immunodeficiency (HP:0004430)3.09115704
18Increased CSF lactate (HP:0002490)3.04128161
19Increased hepatocellular lipid droplets (HP:0006565)3.00623414
203-Methylglutaconic aciduria (HP:0003535)2.98463743
21Abnormality of the anterior horn cell (HP:0006802)2.97771708
22Degeneration of anterior horn cells (HP:0002398)2.97771708
23Oral leukoplakia (HP:0002745)2.89208617
24Breast hypoplasia (HP:0003187)2.88560065
25Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.79271082
2611 pairs of ribs (HP:0000878)2.78264629
27Rough bone trabeculation (HP:0100670)2.75890560
28Lipid accumulation in hepatocytes (HP:0006561)2.70014411
29Type I transferrin isoform profile (HP:0003642)2.69397671
30Exertional dyspnea (HP:0002875)2.68203271
31Increased serum lactate (HP:0002151)2.67531861
32Aplasia/Hypoplasia of the sacrum (HP:0008517)2.66638708
33IgM deficiency (HP:0002850)2.59806638
34Progressive macrocephaly (HP:0004481)2.58701625
35Cerebral hypomyelination (HP:0006808)2.58019005
36Carpal bone hypoplasia (HP:0001498)2.57389788
37Acute encephalopathy (HP:0006846)2.57111763
38Optic disc pallor (HP:0000543)2.56318561
39Multiple enchondromatosis (HP:0005701)2.50526027
40Hypoplasia of the capital femoral epiphysis (HP:0003090)2.49793836
41Combined immunodeficiency (HP:0005387)2.48207887
42Microretrognathia (HP:0000308)2.42598542
43Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.42351160
44Congenital stationary night blindness (HP:0007642)2.41835946
45Dicarboxylic aciduria (HP:0003215)2.40596189
46Abnormality of dicarboxylic acid metabolism (HP:0010995)2.40596189
47Thrombocytosis (HP:0001894)2.36934756
48Abnormality of the heme biosynthetic pathway (HP:0010472)2.34924200
49Pancreatic cysts (HP:0001737)2.33771323
50Elevated erythrocyte sedimentation rate (HP:0003565)2.33360850
51Poor head control (HP:0002421)2.32881223
52Renal cortical cysts (HP:0000803)2.32611755
53Abnormality of T cells (HP:0002843)2.31247566
54Generalized aminoaciduria (HP:0002909)2.30504622
55Pancreatic fibrosis (HP:0100732)2.30462780
56Type 2 muscle fiber atrophy (HP:0003554)2.28945265
57Patellar aplasia (HP:0006443)2.27623012
58Muscle fiber atrophy (HP:0100295)2.26868507
59Methylmalonic aciduria (HP:0012120)2.25360083
60Lethargy (HP:0001254)2.23474393
61Recurrent bronchitis (HP:0002837)2.23301904
62Abnormality of the preputium (HP:0100587)2.22525165
63Abnormality of T cell physiology (HP:0011840)2.20901223
64Pancytopenia (HP:0001876)2.20854309
65Exercise intolerance (HP:0003546)2.20740220
66Aplasia/Hypoplasia of the patella (HP:0006498)2.20293765
67Molar tooth sign on MRI (HP:0002419)2.19726535
68Abnormality of midbrain morphology (HP:0002418)2.19726535
69Agammaglobulinemia (HP:0004432)2.17070036
70Methylmalonic acidemia (HP:0002912)2.15995603
71Abnormality of the ileum (HP:0001549)2.14527533
72Meckel diverticulum (HP:0002245)2.13272151
73Abnormal rod and cone electroretinograms (HP:0008323)2.13158524
74Increased serum pyruvate (HP:0003542)2.13118830
75Abnormality of glycolysis (HP:0004366)2.13118830
76Increased intramyocellular lipid droplets (HP:0012240)2.12589634
77Renal Fanconi syndrome (HP:0001994)2.12426394
78Respiratory difficulties (HP:0002880)2.12084777
79Abnormal trabecular bone morphology (HP:0100671)2.11864255
80Trismus (HP:0000211)2.11722680
81Progressive microcephaly (HP:0000253)2.10852756
82Respiratory failure (HP:0002878)2.08533900
83Petechiae (HP:0000967)2.07829738
84Lactic acidosis (HP:0003128)2.06066018
85Abnormal lung lobation (HP:0002101)2.05179285
86Nephronophthisis (HP:0000090)2.04132463
87Abnormal spermatogenesis (HP:0008669)2.03859221
88Leukodystrophy (HP:0002415)2.03693641
89Cleft eyelid (HP:0000625)2.03101192
90True hermaphroditism (HP:0010459)2.02773742
91Abnormal respiratory epithelium morphology (HP:0012253)2.02676735
92Abnormal respiratory motile cilium morphology (HP:0005938)2.02676735
93Congenital, generalized hypertrichosis (HP:0004540)2.01689782
94Colon cancer (HP:0003003)2.01391947
95Secondary amenorrhea (HP:0000869)1.99352442
96Absent thumb (HP:0009777)1.98988224
97Delayed CNS myelination (HP:0002188)1.98659912
98Selective tooth agenesis (HP:0001592)1.98113392
99Tongue fasciculations (HP:0001308)1.97748709
100Abnormality of renal resorption (HP:0011038)1.97250301
101Chronic otitis media (HP:0000389)1.97248579
102Myositis (HP:0100614)1.96305564
103Bone marrow hypocellularity (HP:0005528)1.95645548
104Abolished electroretinogram (ERG) (HP:0000550)1.95510746
105CNS demyelination (HP:0007305)1.94527552
106Depressed nasal ridge (HP:0000457)1.93334995
107Emotional lability (HP:0000712)1.93018285
108Bronchitis (HP:0012387)1.92323276
109Nasal polyposis (HP:0100582)1.92198864
110T lymphocytopenia (HP:0005403)1.91328603
111Sparse eyelashes (HP:0000653)1.91289167
112Abnormality of urine glucose concentration (HP:0011016)1.91269743
113Glycosuria (HP:0003076)1.91269743
114Brittle hair (HP:0002299)1.90957834
115Neutropenia (HP:0001875)1.90916381
116Decreased electroretinogram (ERG) amplitude (HP:0000654)1.89951422
117Thyroiditis (HP:0100646)1.89569834
118Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.89542713
119Abnormal protein N-linked glycosylation (HP:0012347)1.89542713
120Abnormal protein glycosylation (HP:0012346)1.89542713
121Abnormal glycosylation (HP:0012345)1.89542713
122Absent epiphyses (HP:0010577)1.88311168
123Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.88311168
124Chronic mucocutaneous candidiasis (HP:0002728)1.88271541
125Recurrent cutaneous fungal infections (HP:0011370)1.88271541
126IgG deficiency (HP:0004315)1.87922508
127Hyperglycinemia (HP:0002154)1.87783469
128Triphalangeal thumb (HP:0001199)1.87519971
129Premature graying of hair (HP:0002216)1.87204185
130Myelodysplasia (HP:0002863)1.85246979
131Panhypogammaglobulinemia (HP:0003139)1.84992159
132Duodenal stenosis (HP:0100867)1.84096213
133Small intestinal stenosis (HP:0012848)1.84096213
134Increased muscle lipid content (HP:0009058)1.83964110
135Chromsome breakage (HP:0040012)1.83482165
136Reduced antithrombin III activity (HP:0001976)1.82904240
137Rhinitis (HP:0012384)1.81996299
138Anhidrosis (HP:0000970)1.80901616
139B lymphocytopenia (HP:0010976)1.79003502
140Abnormality of eosinophils (HP:0001879)1.77888738
141Encephalitis (HP:0002383)1.76749808
142Absent rod-and cone-mediated responses on ERG (HP:0007688)1.76702707
143Cerebral palsy (HP:0100021)1.76255016
144Abnormality of T cell number (HP:0011839)1.74268000
145Abnormal delayed hypersensitivity skin test (HP:0002963)1.73175817
146Abnormality of the renal cortex (HP:0011035)1.69978653
147Nausea (HP:0002018)1.69414441
148Abnormality of fatty-acid metabolism (HP:0004359)1.69086701
149Dynein arm defect of respiratory motile cilia (HP:0012255)1.67338844

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB15.28103904
2VRK25.22643130
3WEE14.19037808
4NME23.65183206
5STK163.52028915
6MAP4K22.88613137
7NUAK12.66220674
8EIF2AK12.61544765
9ACVR1B2.53726849
10VRK12.35780213
11SRPK12.34985549
12EIF2AK32.22338246
13BRSK22.21773293
14PIM22.12316041
15CDC72.03835374
16TESK21.91944759
17MUSK1.88943847
18CCNB11.84015833
19ADRBK21.83644353
20DYRK31.82798465
21PLK41.79851116
22KDR1.79516177
23TAOK31.72773995
24GRK61.64693854
25TLK11.63880315
26NEK21.57938441
27TESK11.56778489
28TSSK61.53850312
29MAP4K11.44839257
30PASK1.44649209
31PLK11.40949750
32AURKB1.31172670
33GRK11.29259309
34BRSK11.26134781
35MST41.22175536
36TTK1.21029850
37TEC1.20060753
38NLK1.18658528
39MKNK11.18562653
40IRAK41.18433831
41TGFBR11.15294433
42RPS6KA41.14906948
43RPS6KB21.13923713
44NME11.13462564
45AURKA1.11215924
46DYRK21.07089191
47BRAF1.04679351
48ZAP701.03600463
49MAPKAPK30.98352613
50CDK70.97242375
51BTK0.96374772
52BLK0.96186365
53PDK30.94871590
54PDK40.94871590
55ZAK0.93927194
56PLK30.91615900
57ARAF0.91333732
58CHEK20.90784260
59ATR0.89839988
60BMPR1B0.87655382
61CSNK1G30.86444852
62MAP3K140.85344991
63DAPK10.82179064
64PRKCQ0.81118159
65EPHA20.77176221
66LRRK20.76919031
67CDK80.76347991
68STK100.75849383
69PIM10.75717071
70EIF2AK20.75550893
71LIMK10.73653890
72RPS6KA50.73607338
73NEK10.73169233
74PAK10.72094757
75ILK0.71943216
76MYLK0.71615813
77KIT0.70531352
78CSNK2A10.70254108
79MATK0.68993932
80CLK10.68736148
81FES0.67656172
82PBK0.67440774
83STK40.65454694
84TBK10.64867773
85PAK40.64693737
86MAP3K80.63757749
87IKBKB0.63516497
88CSNK1G20.61164051
89PRKCI0.60593449
90CSNK2A20.59477212
91TXK0.59128228
92GRK70.58974623
93PINK10.58880283
94SYK0.56734904
95IRAK30.56149392
96PHKG10.55339140
97PHKG20.55339140
98DAPK30.55036199
99TNK20.54311111
100MARK30.52396549
101CSF1R0.51975301
102TYK20.51957239
103MAP3K110.51534756
104BCKDK0.51502125
105CHEK10.51258034
106SCYL20.50843947
107LCK0.50836652
108MKNK20.49748485
109ERN10.49300345
110WNK30.49038483
111MAPKAPK50.48370132
112BMPR20.47698239
113LYN0.45474419
114CSNK1G10.44524983
115IKBKE0.44353021
116CDK40.43964692
117ADRBK10.43748687
118CSNK1A1L0.43675059
119PDK20.42954813
120MAP3K120.42066623
121GRK50.40983415
122DYRK1B0.40707583
123JAK30.40176549
124MAP2K30.39468444
125OXSR10.39421915
126WNK40.37284404
127MAPK130.36793762
128IGF1R0.36511671
129ABL20.36232367
130MAPK150.35987652
131YES10.35915973
132MELK0.35261000
133FLT30.35175986
134TAF10.35150349
135CDK190.33306952
136MAP2K20.32354764
137ITK0.31898004

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.89477709
2Proteasome_Homo sapiens_hsa030504.64621464
3DNA replication_Homo sapiens_hsa030304.55862984
4Mismatch repair_Homo sapiens_hsa034303.73258352
5RNA polymerase_Homo sapiens_hsa030203.34462497
6Homologous recombination_Homo sapiens_hsa034403.02927542
7Base excision repair_Homo sapiens_hsa034102.85624500
8Spliceosome_Homo sapiens_hsa030402.85435548
9Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.67778732
10Nucleotide excision repair_Homo sapiens_hsa034202.64471283
11Pyrimidine metabolism_Homo sapiens_hsa002402.58785099
12RNA transport_Homo sapiens_hsa030132.26359929
13Parkinsons disease_Homo sapiens_hsa050122.10388819
14Oxidative phosphorylation_Homo sapiens_hsa001902.09251132
15Protein export_Homo sapiens_hsa030602.07067530
16Cell cycle_Homo sapiens_hsa041101.97248213
17Basal transcription factors_Homo sapiens_hsa030221.85184378
18Fanconi anemia pathway_Homo sapiens_hsa034601.79761506
19Huntingtons disease_Homo sapiens_hsa050161.78030213
20Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.75247281
21Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.65880180
22Non-homologous end-joining_Homo sapiens_hsa034501.64511901
23RNA degradation_Homo sapiens_hsa030181.62052112
24Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.57274049
25Purine metabolism_Homo sapiens_hsa002301.49235585
26Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.47756061
27Primary immunodeficiency_Homo sapiens_hsa053401.41937140
28Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.37588500
29Propanoate metabolism_Homo sapiens_hsa006401.30119022
30One carbon pool by folate_Homo sapiens_hsa006701.28199455
31Type I diabetes mellitus_Homo sapiens_hsa049401.22878888
32Alzheimers disease_Homo sapiens_hsa050101.21968097
33p53 signaling pathway_Homo sapiens_hsa041151.20591015
34Peroxisome_Homo sapiens_hsa041461.18895661
35Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.17419698
36Pentose phosphate pathway_Homo sapiens_hsa000301.17051811
37Sulfur metabolism_Homo sapiens_hsa009201.16254835
38Epstein-Barr virus infection_Homo sapiens_hsa051691.12552771
39Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.06120809
40Antigen processing and presentation_Homo sapiens_hsa046121.03794715
41Tryptophan metabolism_Homo sapiens_hsa003801.03785697
42Vitamin B6 metabolism_Homo sapiens_hsa007501.02984999
43Rheumatoid arthritis_Homo sapiens_hsa053230.96659072
44Butanoate metabolism_Homo sapiens_hsa006500.91106858
45mRNA surveillance pathway_Homo sapiens_hsa030150.90988181
46Systemic lupus erythematosus_Homo sapiens_hsa053220.88618764
47Folate biosynthesis_Homo sapiens_hsa007900.88148347
48Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.85088620
49Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.81980568
50Glutathione metabolism_Homo sapiens_hsa004800.81099965
51Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.77523138
52Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.77188809
53Chemical carcinogenesis_Homo sapiens_hsa052040.76999980
54Herpes simplex infection_Homo sapiens_hsa051680.72470259
55Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.71907904
56Intestinal immune network for IgA production_Homo sapiens_hsa046720.71209075
57Phototransduction_Homo sapiens_hsa047440.71174458
58Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.69165148
59Caffeine metabolism_Homo sapiens_hsa002320.68138324
60Primary bile acid biosynthesis_Homo sapiens_hsa001200.68093665
61Tyrosine metabolism_Homo sapiens_hsa003500.67541154
62Arachidonic acid metabolism_Homo sapiens_hsa005900.66357374
63Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.65996607
64Sulfur relay system_Homo sapiens_hsa041220.65454049
65Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.65102617
66Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.65062555
67Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.62644527
68Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.59989328
69Collecting duct acid secretion_Homo sapiens_hsa049660.59890434
70N-Glycan biosynthesis_Homo sapiens_hsa005100.59027938
71Allograft rejection_Homo sapiens_hsa053300.57881251
72Phenylalanine metabolism_Homo sapiens_hsa003600.54738105
73Viral carcinogenesis_Homo sapiens_hsa052030.54465022
74Asthma_Homo sapiens_hsa053100.54383753
75Regulation of autophagy_Homo sapiens_hsa041400.54112283
76Fatty acid degradation_Homo sapiens_hsa000710.53979128
77Metabolic pathways_Homo sapiens_hsa011000.51165796
78Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.50985755
79Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.50068416
80Legionellosis_Homo sapiens_hsa051340.49751863
81Nitrogen metabolism_Homo sapiens_hsa009100.49650257
82Shigellosis_Homo sapiens_hsa051310.49270710
83Drug metabolism - other enzymes_Homo sapiens_hsa009830.49037783
84Linoleic acid metabolism_Homo sapiens_hsa005910.48949781
852-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.48239339
86Cysteine and methionine metabolism_Homo sapiens_hsa002700.47771053
87Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.46711457
88Measles_Homo sapiens_hsa051620.45035264
89HTLV-I infection_Homo sapiens_hsa051660.44468012
90Pentose and glucuronate interconversions_Homo sapiens_hsa000400.44209559
91NF-kappa B signaling pathway_Homo sapiens_hsa040640.43591381
92Oocyte meiosis_Homo sapiens_hsa041140.43584032
93Cardiac muscle contraction_Homo sapiens_hsa042600.38805744
94Retinol metabolism_Homo sapiens_hsa008300.38725949
95SNARE interactions in vesicular transport_Homo sapiens_hsa041300.37922431
96Carbon metabolism_Homo sapiens_hsa012000.37131368
97Hematopoietic cell lineage_Homo sapiens_hsa046400.36990188
98Fatty acid metabolism_Homo sapiens_hsa012120.36264923
99Biosynthesis of amino acids_Homo sapiens_hsa012300.36238122
100Autoimmune thyroid disease_Homo sapiens_hsa053200.35952125
101Cyanoamino acid metabolism_Homo sapiens_hsa004600.34947334
102Apoptosis_Homo sapiens_hsa042100.34835553
103Steroid hormone biosynthesis_Homo sapiens_hsa001400.34762586
104Staphylococcus aureus infection_Homo sapiens_hsa051500.34499383
105RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.33956992
106beta-Alanine metabolism_Homo sapiens_hsa004100.30728289
107alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.30117878
108Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.28822139
109Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.27757679
110Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.27669348
111Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.25086956
112NOD-like receptor signaling pathway_Homo sapiens_hsa046210.24883751
113Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.23859612
114Viral myocarditis_Homo sapiens_hsa054160.23746967
115Fructose and mannose metabolism_Homo sapiens_hsa000510.23637151
116Alcoholism_Homo sapiens_hsa050340.23407345
117Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.23263234
118Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.22730270
119Thyroid cancer_Homo sapiens_hsa052160.22496757
120Other glycan degradation_Homo sapiens_hsa005110.20358197
121Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.20116206
122Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.19588943
123Renin-angiotensin system_Homo sapiens_hsa046140.18384003
124Transcriptional misregulation in cancer_Homo sapiens_hsa052020.18381619
125Ether lipid metabolism_Homo sapiens_hsa005650.17949252
126Graft-versus-host disease_Homo sapiens_hsa053320.17128922
127Leishmaniasis_Homo sapiens_hsa051400.16881272
128Hepatitis B_Homo sapiens_hsa051610.16377927
129Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.15745771
130Fatty acid elongation_Homo sapiens_hsa000620.13661882
131Galactose metabolism_Homo sapiens_hsa000520.13133742
132Selenocompound metabolism_Homo sapiens_hsa004500.12961851
133Pyruvate metabolism_Homo sapiens_hsa006200.12657118
134Influenza A_Homo sapiens_hsa051640.11099139

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »