NSMCE4A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)5.04577818
2DNA deamination (GO:0045006)5.03428005
3DNA strand elongation involved in DNA replication (GO:0006271)4.84460002
4DNA replication initiation (GO:0006270)4.67708942
5DNA strand elongation (GO:0022616)4.59476762
6telomere maintenance via semi-conservative replication (GO:0032201)4.55502497
7DNA unwinding involved in DNA replication (GO:0006268)4.55267235
8maturation of SSU-rRNA (GO:0030490)4.53248078
9pyrimidine deoxyribonucleotide catabolic process (GO:0009223)4.48884068
10viral transcription (GO:0019083)4.46996205
11translational termination (GO:0006415)4.43956623
12pyrimidine deoxyribonucleotide metabolic process (GO:0009219)4.35373937
13DNA replication checkpoint (GO:0000076)4.27579756
14regulation of DNA methylation (GO:0044030)4.24194335
15protein localization to kinetochore (GO:0034501)4.20334413
16telomere maintenance via recombination (GO:0000722)4.07145726
17formation of translation preinitiation complex (GO:0001731)4.04587475
18translational elongation (GO:0006414)4.03627893
19folic acid-containing compound biosynthetic process (GO:0009396)4.03472967
20nucleobase biosynthetic process (GO:0046112)4.02166581
21ribosomal large subunit biogenesis (GO:0042273)3.93659422
22pyrimidine nucleotide catabolic process (GO:0006244)3.92260602
23mitotic metaphase plate congression (GO:0007080)3.91782117
24chromatin remodeling at centromere (GO:0031055)3.90967009
25mitotic recombination (GO:0006312)3.90852470
26purine nucleobase biosynthetic process (GO:0009113)3.86377804
27CENP-A containing nucleosome assembly (GO:0034080)3.86097533
28translational initiation (GO:0006413)3.84760483
29regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.82095756
30protein localization to chromosome, centromeric region (GO:0071459)3.81578556
31ribosomal small subunit biogenesis (GO:0042274)3.78905638
32nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.75176213
33positive regulation of histone H3-K4 methylation (GO:0051571)3.69241252
34mitotic nuclear envelope disassembly (GO:0007077)3.68043759
35SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.65866679
36DNA replication-independent nucleosome organization (GO:0034724)3.64285903
37DNA replication-independent nucleosome assembly (GO:0006336)3.64285903
38DNA replication-dependent nucleosome assembly (GO:0006335)3.63315417
39DNA replication-dependent nucleosome organization (GO:0034723)3.63315417
40ribosome assembly (GO:0042255)3.61306991
41mitotic chromosome condensation (GO:0007076)3.59286074
42kinetochore organization (GO:0051383)3.59253415
43telomere maintenance via telomere lengthening (GO:0010833)3.58100774
44ribonucleoprotein complex biogenesis (GO:0022613)3.57281198
45protein targeting to ER (GO:0045047)3.53883242
46cotranslational protein targeting to membrane (GO:0006613)3.53802467
47base-excision repair (GO:0006284)3.52671765
48nuclear pore organization (GO:0006999)3.51031745
49folic acid metabolic process (GO:0046655)3.50923574
50regulation of histone H3-K9 methylation (GO:0051570)3.46082978
51ribosome biogenesis (GO:0042254)3.43300277
52metaphase plate congression (GO:0051310)3.42598036
53nucleotide-excision repair, DNA gap filling (GO:0006297)3.40539674
54cellular protein complex disassembly (GO:0043624)3.40340162
55nuclear envelope disassembly (GO:0051081)3.37862621
56membrane disassembly (GO:0030397)3.37862621
57establishment of protein localization to endoplasmic reticulum (GO:0072599)3.36712488
58viral life cycle (GO:0019058)3.36416162
59regulation of mitochondrial translation (GO:0070129)3.35324806
60protein localization to endoplasmic reticulum (GO:0070972)3.33388500
61IMP biosynthetic process (GO:0006188)3.31834396
62rRNA processing (GO:0006364)3.28491861
63kinetochore assembly (GO:0051382)3.27491916
642-deoxyribonucleotide biosynthetic process (GO:0009265)3.21896335
65deoxyribose phosphate biosynthetic process (GO:0046385)3.21896335
66nuclear pore complex assembly (GO:0051292)3.20897935
67centriole replication (GO:0007099)3.19546823
68rRNA metabolic process (GO:0016072)3.18965632
69deoxyribonucleotide biosynthetic process (GO:0009263)3.18466871
70histone exchange (GO:0043486)3.18271371
71mitotic sister chromatid segregation (GO:0000070)3.16652939
72anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.16417952
73meiotic cell cycle (GO:0051321)3.15585806
74exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.14838602
75attachment of spindle microtubules to kinetochore (GO:0008608)3.14133521
76chromatin assembly or disassembly (GO:0006333)3.12793643
77nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.11734717
78postreplication repair (GO:0006301)3.10864911
79protein K6-linked ubiquitination (GO:0085020)3.10756116
80base-excision repair, AP site formation (GO:0006285)3.09914071
81protein complex disassembly (GO:0043241)3.09848361
82pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.09198471
83regulation of spindle organization (GO:0090224)3.08673926
84deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.07840149
85negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.07682134
86nuclear-transcribed mRNA catabolic process (GO:0000956)3.07247201
87negative regulation of RNA splicing (GO:0033119)3.04554923
88mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.04240372
89spliceosomal snRNP assembly (GO:0000387)3.03511162
90DNA duplex unwinding (GO:0032508)3.03038080
91DNA ligation (GO:0006266)3.02550683
92regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.02501736
93translesion synthesis (GO:0019985)3.02178103
94DNA geometric change (GO:0032392)3.01617633
95establishment of chromosome localization (GO:0051303)3.01269243
96regulation of nuclear cell cycle DNA replication (GO:0033262)3.00835150
97viral mRNA export from host cell nucleus (GO:0046784)3.00496840
98deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.99060580
99deoxyribonucleotide catabolic process (GO:0009264)2.97486055
100IMP metabolic process (GO:0046040)2.97162434
101pseudouridine synthesis (GO:0001522)2.96915613
102chromatin assembly (GO:0031497)2.96670262
103mitochondrial respiratory chain complex I assembly (GO:0032981)2.95868055
104NADH dehydrogenase complex assembly (GO:0010257)2.95868055
105mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.95868055
106proteasome assembly (GO:0043248)2.94757076
107RNA catabolic process (GO:0006401)2.93985343
108sister chromatid segregation (GO:0000819)2.93948244
109negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.93834187
110mRNA catabolic process (GO:0006402)2.93234862
111pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.92193931
112pteridine-containing compound biosynthetic process (GO:0042559)2.91595720
113macromolecular complex disassembly (GO:0032984)2.91388406
114regulation of double-strand break repair via homologous recombination (GO:0010569)2.89969966
115translation (GO:0006412)2.87014001
116regulation of helicase activity (GO:0051095)2.85502556
117RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.85354275
118tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.85354275
119maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.84082131
120energy coupled proton transport, down electrochemical gradient (GO:0015985)2.83544208
121ATP synthesis coupled proton transport (GO:0015986)2.83544208
122rRNA modification (GO:0000154)2.83159991
123transcription-coupled nucleotide-excision repair (GO:0006283)2.81138862
124positive regulation of chromosome segregation (GO:0051984)2.80867772
125telomere maintenance (GO:0000723)2.80084718
126meiotic chromosome segregation (GO:0045132)2.80009849
127deoxyribose phosphate catabolic process (GO:0046386)2.79461031
128regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.79265008
129regulation of chromosome segregation (GO:0051983)2.78936012
130telomere organization (GO:0032200)2.78902159
131protein localization to chromosome (GO:0034502)2.78497101
132somatic diversification of immune receptors via somatic mutation (GO:0002566)2.77860889
133somatic hypermutation of immunoglobulin genes (GO:0016446)2.77860889
134negative regulation of chromosome segregation (GO:0051985)2.76470280
135mismatch repair (GO:0006298)2.74842641
136spindle checkpoint (GO:0031577)2.73953540
137negative regulation of mitotic sister chromatid segregation (GO:0033048)2.73831360
138negative regulation of sister chromatid segregation (GO:0033046)2.73831360

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.55765167
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.09393821
3FOXM1_23109430_ChIP-Seq_U2OS_Human4.04395970
4* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.80510546
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.55520131
6FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.07853476
7MYC_19079543_ChIP-ChIP_MESCs_Mouse2.84899853
8HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.67635771
9MYC_19030024_ChIP-ChIP_MESCs_Mouse2.66445033
10MYC_18358816_ChIP-ChIP_MESCs_Mouse2.64592799
11KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.56938912
12ETS1_20019798_ChIP-Seq_JURKAT_Human2.47612935
13EST1_17652178_ChIP-ChIP_JURKAT_Human2.45111913
14GABP_17652178_ChIP-ChIP_JURKAT_Human2.43146240
15JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.41612147
16CREB1_15753290_ChIP-ChIP_HEK293T_Human2.32729136
17EZH2_22144423_ChIP-Seq_EOC_Human2.24571348
18NELFA_20434984_ChIP-Seq_ESCs_Mouse2.22407151
19XRN2_22483619_ChIP-Seq_HELA_Human2.22120695
20AR_21909140_ChIP-Seq_LNCAP_Human2.14925075
21VDR_23849224_ChIP-Seq_CD4+_Human2.13565957
22E2F1_21310950_ChIP-Seq_MCF-7_Human2.05127626
23MYC_22102868_ChIP-Seq_BL_Human2.04374149
24HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.94755843
25EGR1_19374776_ChIP-ChIP_THP-1_Human1.94615269
26CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.91058443
27E2F1_18555785_ChIP-Seq_MESCs_Mouse1.88302311
28SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.87312623
29DCP1A_22483619_ChIP-Seq_HELA_Human1.86296630
30FOXP3_21729870_ChIP-Seq_TREG_Human1.86122905
31ELF1_17652178_ChIP-ChIP_JURKAT_Human1.82036328
32TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.77241457
33MYCN_18555785_ChIP-Seq_MESCs_Mouse1.77198504
34* GABP_19822575_ChIP-Seq_HepG2_Human1.76413029
35E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.76316798
36IRF1_19129219_ChIP-ChIP_H3396_Human1.74760266
37MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.74759648
38MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.71886882
39TTF2_22483619_ChIP-Seq_HELA_Human1.65843098
40* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.63529411
41POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.62562675
42ZFX_18555785_ChIP-Seq_MESCs_Mouse1.62432205
43CIITA_25753668_ChIP-Seq_RAJI_Human1.62019164
44SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.59647986
45NANOG_18555785_ChIP-Seq_MESCs_Mouse1.58121096
46NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.53997404
47BP1_19119308_ChIP-ChIP_Hs578T_Human1.48358554
48KDM5A_27292631_Chip-Seq_BREAST_Human1.47521324
49FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.47481866
50HOXB4_20404135_ChIP-ChIP_EML_Mouse1.45896357
51HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.43409011
52THAP11_20581084_ChIP-Seq_MESCs_Mouse1.43115394
53KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.41977691
54STAT3_1855785_ChIP-Seq_MESCs_Mouse1.41511536
55SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.40651041
56ERG_20887958_ChIP-Seq_HPC-7_Mouse1.38014980
57ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.35886548
58ELK1_19687146_ChIP-ChIP_HELA_Human1.33496291
59VDR_21846776_ChIP-Seq_THP-1_Human1.32809775
60FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.31131655
61ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.29648680
62ESR1_15608294_ChIP-ChIP_MCF-7_Human1.29493744
63YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.27326370
64KLF4_18555785_ChIP-Seq_MESCs_Mouse1.26033367
65FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.24647118
66* YY1_21170310_ChIP-Seq_MESCs_Mouse1.20802412
67SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.20098534
68SRF_21415370_ChIP-Seq_HL-1_Mouse1.16680685
69MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.16186898
70* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.14744600
71CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.13887659
72DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.13695440
73SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.13497738
74POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.12145201
75CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.11136061
76TFEB_21752829_ChIP-Seq_HELA_Human1.09457092
77ZNF263_19887448_ChIP-Seq_K562_Human1.08148535
78POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.05552060
79TP63_19390658_ChIP-ChIP_HaCaT_Human1.03880150
80TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.03302616
81NOTCH1_21737748_ChIP-Seq_TLL_Human1.02971437
82GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.00571560
83SPI1_23547873_ChIP-Seq_NB4_Human1.00468940
84KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.98781776
85KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.98781776
86KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.98781776
87BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.98052895
88KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.97867914
89PADI4_21655091_ChIP-ChIP_MCF-7_Human0.96267367
90SOX2_18555785_ChIP-Seq_MESCs_Mouse0.96221829
91* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.95442571
92CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.94160737
93GATA1_26923725_Chip-Seq_HPCs_Mouse0.93739921
94KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.91326773
95MYC_18940864_ChIP-ChIP_HL60_Human0.89115131
96RBPJ_22232070_ChIP-Seq_NCS_Mouse0.87415345
97GATA1_22383799_ChIP-Seq_G1ME_Mouse0.85397886
98CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.85383235
99CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.85262126
100CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.84142160
101EWS_26573619_Chip-Seq_HEK293_Human0.83936351
102SCL_19346495_ChIP-Seq_HPC-7_Human0.83633270
103NANOG_21062744_ChIP-ChIP_HESCs_Human0.80882708
104PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.80516292
105MYB_21317192_ChIP-Seq_ERMYB_Mouse0.80468218
106CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.79629126
107MAF_26560356_Chip-Seq_TH1_Human0.79480176
108CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.79168646
109SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.78820234
110CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.78787220
111ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.78068210
112CTCF_18555785_ChIP-Seq_MESCs_Mouse0.77220105
113HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.76995825
114ZNF274_21170338_ChIP-Seq_K562_Hela0.75925247
115CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.75745091
116HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.75264017
117PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.69323206
118HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.67600729
119TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.66801762
120ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.65834541

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.31581188
2MP0006292_abnormal_olfactory_placode4.74511064
3MP0003111_abnormal_nucleus_morphology4.36797957
4MP0004957_abnormal_blastocyst_morpholog4.34969355
5MP0010094_abnormal_chromosome_stability4.28367881
6MP0003077_abnormal_cell_cycle3.79766785
7MP0008057_abnormal_DNA_replication3.45384350
8MP0008789_abnormal_olfactory_epithelium3.30719122
9MP0008058_abnormal_DNA_repair2.84540772
10MP0002396_abnormal_hematopoietic_system2.77005956
11MP0005499_abnormal_olfactory_system2.65110303
12MP0005394_taste/olfaction_phenotype2.65110303
13MP0008007_abnormal_cellular_replicative2.54978460
14MP0003123_paternal_imprinting2.23745818
15MP0000490_abnormal_crypts_of2.21826318
16MP0001730_embryonic_growth_arrest2.12554620
17MP0008932_abnormal_embryonic_tissue2.09930745
18MP0000350_abnormal_cell_proliferation2.03353338
19MP0010352_gastrointestinal_tract_polyps1.97172001
20MP0000566_synostosis1.96655244
21MP0003806_abnormal_nucleotide_metabolis1.95468002
22MP0010307_abnormal_tumor_latency1.84225140
23MP0006054_spinal_hemorrhage1.72550344
24MP0002234_abnormal_pharynx_morphology1.72531082
25MP0005397_hematopoietic_system_phenotyp1.61740113
26MP0001545_abnormal_hematopoietic_system1.61740113
27MP0004808_abnormal_hematopoietic_stem1.60226436
28MP0003567_abnormal_fetal_cardiomyocyte1.60137642
29MP0001672_abnormal_embryogenesis/_devel1.59395736
30MP0005380_embryogenesis_phenotype1.59395736
31MP0009333_abnormal_splenocyte_physiolog1.57299270
32MP0001697_abnormal_embryo_size1.56361241
33MP0002019_abnormal_tumor_incidence1.54956443
34MP0001529_abnormal_vocalization1.54906519
35MP0003786_premature_aging1.54663734
36MP0002080_prenatal_lethality1.53144673
37MP0003890_abnormal_embryonic-extraembry1.52755923
38MP0005395_other_phenotype1.49097443
39MP0002163_abnormal_gland_morphology1.48618408
40MP0003763_abnormal_thymus_physiology1.48325912
41MP0003984_embryonic_growth_retardation1.43567122
42MP0002086_abnormal_extraembryonic_tissu1.40344133
43MP0000313_abnormal_cell_death1.40260786
44MP0002088_abnormal_embryonic_growth/wei1.39984089
45MP0009697_abnormal_copulation1.39141414
46MP0002398_abnormal_bone_marrow1.38991420
47MP0000049_abnormal_middle_ear1.36440157
48MP0003718_maternal_effect1.31164246
49MP0002085_abnormal_embryonic_tissue1.29344537
50MP0002722_abnormal_immune_system1.25165817
51MP0003186_abnormal_redox_activity1.23952501
52MP0000703_abnormal_thymus_morphology1.22640014
53MP0000689_abnormal_spleen_morphology1.21211425
54MP0003656_abnormal_erythrocyte_physiolo1.19343034
55MP0006035_abnormal_mitochondrial_morpho1.18374182
56MP0003699_abnormal_female_reproductive1.17790490
57MP0002084_abnormal_developmental_patter1.17237333
58MP0005360_urolithiasis1.16760989
59MP0004197_abnormal_fetal_growth/weight/1.16711335
60MP0008995_early_reproductive_senescence1.13890825
61MP0002132_abnormal_respiratory_system1.12830471
62MP0004142_abnormal_muscle_tone1.12607552
63MP0000631_abnormal_neuroendocrine_gland1.10954037
64MP0002429_abnormal_blood_cell1.10274915
65MP0008877_abnormal_DNA_methylation1.09378845
66MP0005076_abnormal_cell_differentiation1.07279080
67MP0000685_abnormal_immune_system1.02757917
68MP0006036_abnormal_mitochondrial_physio1.00726099
69MP0004147_increased_porphyrin_level1.00455497
70MP0002233_abnormal_nose_morphology0.98935309
71MP0000716_abnormal_immune_system0.98026476
72MP0001835_abnormal_antigen_presentation0.95106557
73MP0002210_abnormal_sex_determination0.94916253
74MP0002166_altered_tumor_susceptibility0.93980456
75MP0002139_abnormal_hepatobiliary_system0.92317039
76MP0001145_abnormal_male_reproductive0.89447061
77MP0002161_abnormal_fertility/fecundity0.89241240
78MP0001800_abnormal_humoral_immune0.88535070
79MP0002938_white_spotting0.87501049
80MP0009278_abnormal_bone_marrow0.86868933
81MP0000477_abnormal_intestine_morphology0.86474406
82MP0001764_abnormal_homeostasis0.85619850
83MP0003221_abnormal_cardiomyocyte_apopto0.85561165
84MP0001293_anophthalmia0.85229560
85MP0003698_abnormal_male_reproductive0.85106053
86MP0004264_abnormal_extraembryonic_tissu0.83807047
87MP0000465_gastrointestinal_hemorrhage0.83293382
88MP0005645_abnormal_hypothalamus_physiol0.83259602
89MP0000358_abnormal_cell_content/0.80544801
90MP0000858_altered_metastatic_potential0.78739488
91MP0001853_heart_inflammation0.78650371
92MP0000653_abnormal_sex_gland0.76933714
93MP0002006_tumorigenesis0.76248177
94MP0002420_abnormal_adaptive_immunity0.75774114
95MP0001929_abnormal_gametogenesis0.75671638
96MP0001819_abnormal_immune_cell0.74104983
97MP0000537_abnormal_urethra_morphology0.73153573
98MP0002452_abnormal_antigen_presenting0.73091736
99MP0010155_abnormal_intestine_physiology0.72178095
100MP0003121_genomic_imprinting0.71685658
101MP0005671_abnormal_response_to0.71535002
102MP0009840_abnormal_foam_cell0.71315578
103MP0009672_abnormal_birth_weight0.71162779
104MP0001119_abnormal_female_reproductive0.70746070
105MP0003315_abnormal_perineum_morphology0.70631610
106MP0002653_abnormal_ependyma_morphology0.70557459
107MP0005377_hearing/vestibular/ear_phenot0.70314933
108MP0003878_abnormal_ear_physiology0.70314933
109MP0002138_abnormal_hepatobiliary_system0.70066170
110MP0000598_abnormal_liver_morphology0.68949699
111MP0006072_abnormal_retinal_apoptosis0.68886822
112MP0009379_abnormal_foot_pigmentation0.68201657
113MP0002095_abnormal_skin_pigmentation0.67336005
114MP0001873_stomach_inflammation0.67284373
115MP0002405_respiratory_system_inflammati0.66674456
116MP0005075_abnormal_melanosome_morpholog0.66537864
117MP0004133_heterotaxia0.66207272
118MP0001986_abnormal_taste_sensitivity0.66181271
119MP0002723_abnormal_immune_serum0.65509134
120MP0001286_abnormal_eye_development0.65473442
121MP0005647_abnormal_sex_gland0.64912725
122MP0005174_abnormal_tail_pigmentation0.64901440
123MP0001919_abnormal_reproductive_system0.64893244
124MP0001849_ear_inflammation0.64539989
125MP0009053_abnormal_anal_canal0.63145229
126MP0005384_cellular_phenotype0.63078842
127MP0001915_intracranial_hemorrhage0.60246221
128MP0005621_abnormal_cell_physiology0.59288655
129MP0005410_abnormal_fertilization0.59020368
130MP0003122_maternal_imprinting0.58466998
131MP0005266_abnormal_metabolism0.57948735
132MP0005379_endocrine/exocrine_gland_phen0.57694746
133MP0002877_abnormal_melanocyte_morpholog0.57639645
134MP0003787_abnormal_imprinting0.57619752
135MP0002092_abnormal_eye_morphology0.57540181
136MP0005389_reproductive_system_phenotype0.57502073
137MP0003705_abnormal_hypodermis_morpholog0.56530069
138MP0002160_abnormal_reproductive_system0.56335524
139MP0001346_abnormal_lacrimal_gland0.55675412
140MP0003119_abnormal_digestive_system0.55050470
141MP0000372_irregular_coat_pigmentation0.54924319
142MP0010030_abnormal_orbit_morphology0.54137766

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)5.59530137
2Abnormal number of erythroid precursors (HP:0012131)5.42781382
3Birth length less than 3rd percentile (HP:0003561)5.16318353
4Reticulocytopenia (HP:0001896)5.00423868
5Breast hypoplasia (HP:0003187)3.75576471
6Oral leukoplakia (HP:0002745)3.61422386
7Colon cancer (HP:0003003)3.51388997
8Macrocytic anemia (HP:0001972)3.47778881
9Aplastic anemia (HP:0001915)3.43765906
10Pallor (HP:0000980)3.36527531
11Abnormality of the heme biosynthetic pathway (HP:0010472)3.36057802
12Chromsome breakage (HP:0040012)3.16536159
13Hepatic necrosis (HP:0002605)3.13403791
14Median cleft lip (HP:0000161)3.10025769
15Microretrognathia (HP:0000308)3.07871416
16Multiple enchondromatosis (HP:0005701)3.07776305
17Thrombocytosis (HP:0001894)3.04266986
18Abnormality of chromosome stability (HP:0003220)3.03486839
19Hepatocellular necrosis (HP:0001404)3.02631818
20Selective tooth agenesis (HP:0001592)3.02233456
21Chromosomal breakage induced by crosslinking agents (HP:0003221)2.97861966
22Patellar aplasia (HP:0006443)2.97778960
23Microvesicular hepatic steatosis (HP:0001414)2.92039057
24Aplasia/Hypoplasia of the patella (HP:0006498)2.84800772
25B lymphocytopenia (HP:0010976)2.79904190
26Abnormal mitochondria in muscle tissue (HP:0008316)2.79812346
27Acute necrotizing encephalopathy (HP:0006965)2.78939966
28Myelodysplasia (HP:0002863)2.77779351
29Ependymoma (HP:0002888)2.76748684
30Rhabdomyosarcoma (HP:0002859)2.75259795
31Meckel diverticulum (HP:0002245)2.74809083
32Medulloblastoma (HP:0002885)2.74235831
33Abnormality of the preputium (HP:0100587)2.70700450
34Mitochondrial inheritance (HP:0001427)2.68473799
35Acute encephalopathy (HP:0006846)2.64948888
36Abnormality of reticulocytes (HP:0004312)2.63477105
37Combined immunodeficiency (HP:0005387)2.62640883
38Absent thumb (HP:0009777)2.62417771
39IgM deficiency (HP:0002850)2.60641071
40Abnormality of the ileum (HP:0001549)2.58981342
41Rough bone trabeculation (HP:0100670)2.58824963
42Generalized aminoaciduria (HP:0002909)2.57889356
43Abnormality of B cell number (HP:0010975)2.57159285
44Impulsivity (HP:0100710)2.56590845
45Increased CSF lactate (HP:0002490)2.55341382
46Carpal bone hypoplasia (HP:0001498)2.53168893
47Panhypogammaglobulinemia (HP:0003139)2.50893357
48Degeneration of anterior horn cells (HP:0002398)2.47678843
49Abnormality of the anterior horn cell (HP:0006802)2.47678843
503-Methylglutaconic aciduria (HP:0003535)2.46020614
51Severe combined immunodeficiency (HP:0004430)2.45794717
52Basal cell carcinoma (HP:0002671)2.43958710
53Progressive muscle weakness (HP:0003323)2.42436315
54Agnosia (HP:0010524)2.42119361
55Neoplasm of the pancreas (HP:0002894)2.41068255
56Aplasia/Hypoplasia of the uvula (HP:0010293)2.38255123
57Increased serum lactate (HP:0002151)2.36619526
58Septo-optic dysplasia (HP:0100842)2.34918689
59Increased intramyocellular lipid droplets (HP:0012240)2.30784431
6011 pairs of ribs (HP:0000878)2.30424609
61Bone marrow hypocellularity (HP:0005528)2.30035431
62Duodenal stenosis (HP:0100867)2.29610838
63Small intestinal stenosis (HP:0012848)2.29610838
64Abnormality of the labia minora (HP:0012880)2.19652381
65Prominent nose (HP:0000448)2.19132215
66Renal cortical cysts (HP:0000803)2.18837504
67Lymphoma (HP:0002665)2.18285588
68Premature ovarian failure (HP:0008209)2.14207446
69Short thumb (HP:0009778)2.11955502
70Pancytopenia (HP:0001876)2.10890162
71Short tibia (HP:0005736)2.10778116
72Secondary amenorrhea (HP:0000869)2.09379637
73Increased muscle lipid content (HP:0009058)2.08246416
74Atresia of the external auditory canal (HP:0000413)2.07360934
75Poikiloderma (HP:0001029)2.07341894
76Increased hepatocellular lipid droplets (HP:0006565)2.06459059
77Lactic acidosis (HP:0003128)2.05991429
78Capillary hemangiomas (HP:0005306)2.03247409
79Aplasia/Hypoplasia of the sacrum (HP:0008517)2.01720341
80Progressive macrocephaly (HP:0004481)2.01360600
81Squamous cell carcinoma (HP:0002860)2.00621698
82Cellular immunodeficiency (HP:0005374)1.99911546
83Sloping forehead (HP:0000340)1.98918430
84Premature graying of hair (HP:0002216)1.98793190
85Abnormality of abdominal situs (HP:0011620)1.98691551
86Abdominal situs inversus (HP:0003363)1.98691551
87Amaurosis fugax (HP:0100576)1.98494549
88Cerebral hypomyelination (HP:0006808)1.97956295
89Entropion (HP:0000621)1.97084524
90Lipid accumulation in hepatocytes (HP:0006561)1.96852835
91Abnormality of pyrimidine metabolism (HP:0004353)1.95754193
92Cerebral edema (HP:0002181)1.95372921
93Slender long bone (HP:0003100)1.94034160
94Tracheoesophageal fistula (HP:0002575)1.93370336
95High pitched voice (HP:0001620)1.92091415
96IgG deficiency (HP:0004315)1.91902060
97Dicarboxylic aciduria (HP:0003215)1.91030001
98Abnormality of dicarboxylic acid metabolism (HP:0010995)1.91030001
99Spastic diplegia (HP:0001264)1.90960985
100Abnormality of the fovea (HP:0000493)1.90593270
101Abnormality of the duodenum (HP:0002246)1.90374173
102Horseshoe kidney (HP:0000085)1.90213419
103Trismus (HP:0000211)1.89913579
104Aplasia/Hypoplasia of the tibia (HP:0005772)1.89619096
105Nephroblastoma (Wilms tumor) (HP:0002667)1.89378689
106Megaloblastic anemia (HP:0001889)1.85513825
107Cafe-au-lait spot (HP:0000957)1.85421836
108Neoplasm of striated muscle (HP:0009728)1.84764868
109Absent radius (HP:0003974)1.83675412
110Petechiae (HP:0000967)1.83207839
111Triphalangeal thumb (HP:0001199)1.83046767
112Abnormality of DNA repair (HP:0003254)1.82731892
113Hyperglycinemia (HP:0002154)1.82677309
114Facial hemangioma (HP:0000329)1.82336222
115Molar tooth sign on MRI (HP:0002419)1.81464854
116Abnormality of midbrain morphology (HP:0002418)1.81464854
117Muscle fiber atrophy (HP:0100295)1.81370663
118Facial cleft (HP:0002006)1.81313314
119Abnormal trabecular bone morphology (HP:0100671)1.81309222
120Abnormal spermatogenesis (HP:0008669)1.80442080
121Hypoplasia of the fovea (HP:0007750)1.80360416
122Aplasia/Hypoplasia of the fovea (HP:0008060)1.80360416
123Preaxial hand polydactyly (HP:0001177)1.80255035
124Abnormal number of incisors (HP:0011064)1.80234932
125Neoplasm of the colon (HP:0100273)1.79623553
126Renal Fanconi syndrome (HP:0001994)1.79070634
127Progressive microcephaly (HP:0000253)1.79006788
128Type 2 muscle fiber atrophy (HP:0003554)1.78659303
129Proximal placement of thumb (HP:0009623)1.78551754
130Missing ribs (HP:0000921)1.78474651
131Oligodactyly (HP:0012165)1.78259455
132Abnormality of the carotid arteries (HP:0005344)1.78244858
133Absent septum pellucidum (HP:0001331)1.77517445
134Decreased activity of mitochondrial respiratory chain (HP:0008972)1.76815636
135Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.76815636
136Increased nuchal translucency (HP:0010880)1.75508059
137Absent rod-and cone-mediated responses on ERG (HP:0007688)1.73001591
138Abnormality of T cell physiology (HP:0011840)1.72456665
139Recurrent bronchitis (HP:0002837)1.72132017
140Overlapping toe (HP:0001845)1.71607090
141Embryonal renal neoplasm (HP:0011794)1.71592910
142Supernumerary spleens (HP:0009799)1.70961458
143Clubbing of toes (HP:0100760)1.70055862
144Abnormality of lateral ventricle (HP:0030047)1.69188213
145Reduced antithrombin III activity (HP:0001976)1.68660561
146Absent forearm bone (HP:0003953)1.68510070
147Aplasia involving forearm bones (HP:0009822)1.68510070
148Poikilocytosis (HP:0004447)1.67984042
149Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.66703578
150Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.66458351
151Abnormal lung lobation (HP:0002101)1.64911939
152Abnormality of T cells (HP:0002843)1.64696232
153Cleft eyelid (HP:0000625)1.64685218

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WEE14.19488251
2BUB13.74222699
3CDC73.69276858
4NEK23.44074538
5VRK23.15726738
6NME22.99621219
7ACVR1B2.78749413
8MAP3K132.66783019
9MAP4K22.61210983
10ARAF2.41847027
11EIF2AK12.29275183
12DYRK32.26911877
13EEF2K2.12646022
14TTK2.12320825
15BRSK22.11974175
16SRPK12.08056233
17TLK11.99384385
18NEK11.94239205
19RPS6KB21.89201308
20SCYL21.87423857
21FLT31.83428428
22PLK11.78515580
23NUAK11.77235668
24AURKB1.72197148
25PKN21.70455547
26RPS6KA41.68914179
27VRK11.68051729
28TAOK31.66470760
29CDK41.65387324
30EIF2AK31.64456520
31CDK71.57674182
32MAP3K101.49059039
33MAP4K11.47182307
34TSSK61.47098696
35PLK41.46762381
36PASK1.46507480
37ATR1.46168549
38MAP3K81.43693312
39TESK21.42897330
40MAP3K91.42567160
41STK101.38141419
42STK161.37868594
43MKNK11.36235584
44TRIB31.34724464
45TIE11.34139501
46MKNK21.33816727
47CHEK21.33567244
48TGFBR11.27161753
49BRSK11.20422265
50STK41.12794680
51LRRK21.12524422
52MAP2K31.11893844
53AURKA1.08833228
54NME11.08738159
55PIM11.07457654
56PBK1.07310383
57CDK121.03307205
58CHEK11.03010300
59STK241.01483632
60CSNK1G31.00774458
61CCNB10.97633369
62MST40.96574215
63WNK40.94847291
64PAK40.94625632
65BCKDK0.94112544
66PLK30.94053043
67MAP2K70.91219982
68GRK60.87724692
69DYRK20.85252189
70ZAK0.81894984
71KDR0.81574884
72ZAP700.80510692
73CSNK1G10.79000940
74CSNK1A1L0.78998529
75JAK30.78497214
76CDK80.78419818
77CDK20.75111091
78CDK60.74696007
79ATM0.73308548
80EPHA20.69705421
81MAPKAPK30.69026843
82ILK0.67393570
83TEC0.67308297
84CSNK2A20.64564019
85MELK0.64221227
86TAF10.63899380
87BTK0.63712610
88TYK20.63517154
89MAPK110.61990100
90STK30.60233040
91CSNK1G20.58977122
92ALK0.58825620
93CSNK2A10.58201882
94MAP2K20.54340191
95BMPR1B0.53935625
96TRIM280.51191407
97MAP3K110.49813182
98AKT20.49590602
99NEK60.49558622
100KIT0.48999789
101PAK10.48521465
102MAP3K40.47231976
103MOS0.46114956
104CDK10.45002878
105BLK0.42209071
106PIM20.40471625
107STK390.39984553
108RPS6KA50.39727347
109TXK0.39700811
110RAF10.39267863
111CSF1R0.36740578
112PRKCI0.35984377
113CDK190.33337778
114MAP3K30.33264016
115NLK0.32849268
116EIF2AK20.32749097
117CDK90.32740736
118PIK3CA0.32580669
119MAPKAPK50.32441932
120CDK11A0.31357018
121MARK30.29048280
122MTOR0.27504887
123DYRK1B0.27134468
124CSNK1E0.26278666
125STK38L0.25084166
126CLK10.24768449
127ABL20.24486685
128MATK0.24273481
129TNK20.24137073
130IKBKE0.23000001
131BRAF0.22723985
132CDK150.22363937
133SYK0.21553902
134MAP3K50.21366103
135IKBKB0.21020365
136PRKDC0.20589059
137RPS6KA10.20116645

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.15682859
2Mismatch repair_Homo sapiens_hsa034304.25110326
3Ribosome_Homo sapiens_hsa030103.80873302
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.21442799
5Spliceosome_Homo sapiens_hsa030403.09808263
6Base excision repair_Homo sapiens_hsa034102.99845810
7Homologous recombination_Homo sapiens_hsa034402.92366585
8RNA transport_Homo sapiens_hsa030132.86278683
9RNA polymerase_Homo sapiens_hsa030202.84148758
10Nucleotide excision repair_Homo sapiens_hsa034202.76472941
11Cell cycle_Homo sapiens_hsa041102.66727059
12One carbon pool by folate_Homo sapiens_hsa006702.58517018
13Proteasome_Homo sapiens_hsa030502.54188198
14Pyrimidine metabolism_Homo sapiens_hsa002402.47353562
15Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.07591301
16Fanconi anemia pathway_Homo sapiens_hsa034602.02429031
17Oxidative phosphorylation_Homo sapiens_hsa001902.00559011
18Parkinsons disease_Homo sapiens_hsa050121.92128334
19RNA degradation_Homo sapiens_hsa030181.76919278
20Fatty acid elongation_Homo sapiens_hsa000621.67627091
21Non-homologous end-joining_Homo sapiens_hsa034501.64407912
22Basal transcription factors_Homo sapiens_hsa030221.58871670
23p53 signaling pathway_Homo sapiens_hsa041151.56354677
24mRNA surveillance pathway_Homo sapiens_hsa030151.49472070
25Systemic lupus erythematosus_Homo sapiens_hsa053221.46914521
26Folate biosynthesis_Homo sapiens_hsa007901.41570332
27Pentose phosphate pathway_Homo sapiens_hsa000301.24967194
28Selenocompound metabolism_Homo sapiens_hsa004501.23370256
29Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.22622998
30Purine metabolism_Homo sapiens_hsa002301.21714037
31Sulfur relay system_Homo sapiens_hsa041221.14531938
32Cysteine and methionine metabolism_Homo sapiens_hsa002701.13593195
33Drug metabolism - other enzymes_Homo sapiens_hsa009831.11719986
34Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.08898940
35Herpes simplex infection_Homo sapiens_hsa051681.05266621
36Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.04965165
37Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.03984044
38Antigen processing and presentation_Homo sapiens_hsa046121.03487428
39Vitamin B6 metabolism_Homo sapiens_hsa007501.02270761
40Biosynthesis of amino acids_Homo sapiens_hsa012301.01644547
41Epstein-Barr virus infection_Homo sapiens_hsa051690.96426599
42Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.91823571
43Alzheimers disease_Homo sapiens_hsa050100.91276504
44Viral carcinogenesis_Homo sapiens_hsa052030.89559218
45Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.88356237
46Cyanoamino acid metabolism_Homo sapiens_hsa004600.88160476
47Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.82924446
48Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.80607430
49Primary immunodeficiency_Homo sapiens_hsa053400.80174172
50Propanoate metabolism_Homo sapiens_hsa006400.79661497
51Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.78448817
52Asthma_Homo sapiens_hsa053100.76047917
53Carbon metabolism_Homo sapiens_hsa012000.74570813
54Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.73367007
55Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.72202364
562-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.71391490
57Thyroid cancer_Homo sapiens_hsa052160.70284271
58Oocyte meiosis_Homo sapiens_hsa041140.68379203
59HTLV-I infection_Homo sapiens_hsa051660.66926373
60Peroxisome_Homo sapiens_hsa041460.66208277
61Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.64331059
62Allograft rejection_Homo sapiens_hsa053300.63121591
63Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.61323313
64Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.61156586
65Small cell lung cancer_Homo sapiens_hsa052220.60219394
66Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.60124159
67Glutathione metabolism_Homo sapiens_hsa004800.58165753
68Legionellosis_Homo sapiens_hsa051340.57050477
69Transcriptional misregulation in cancer_Homo sapiens_hsa052020.55173591
70Cardiac muscle contraction_Homo sapiens_hsa042600.52295574
71Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.52129318
72Autoimmune thyroid disease_Homo sapiens_hsa053200.48761857
73Phototransduction_Homo sapiens_hsa047440.45487256
74Apoptosis_Homo sapiens_hsa042100.43993707
75N-Glycan biosynthesis_Homo sapiens_hsa005100.43855819
76Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.42447617
77Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.40063252
78Olfactory transduction_Homo sapiens_hsa047400.39632805
79NF-kappa B signaling pathway_Homo sapiens_hsa040640.39102606
80Alcoholism_Homo sapiens_hsa050340.38193384
81Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.37994007
82Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.37990765
83MicroRNAs in cancer_Homo sapiens_hsa052060.37733312
84Measles_Homo sapiens_hsa051620.37637333
85Fructose and mannose metabolism_Homo sapiens_hsa000510.36900022
86Hepatitis B_Homo sapiens_hsa051610.35381796
87Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.34269113
88Intestinal immune network for IgA production_Homo sapiens_hsa046720.34269058
89Chronic myeloid leukemia_Homo sapiens_hsa052200.34227232
90Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.32241613
91B cell receptor signaling pathway_Homo sapiens_hsa046620.30000333
92Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.29153401
93Bladder cancer_Homo sapiens_hsa052190.28727928
94Graft-versus-host disease_Homo sapiens_hsa053320.28683371
95Butanoate metabolism_Homo sapiens_hsa006500.28234173
96Protein export_Homo sapiens_hsa030600.27973388
97Colorectal cancer_Homo sapiens_hsa052100.27631630
98Galactose metabolism_Homo sapiens_hsa000520.27472772
99Regulation of autophagy_Homo sapiens_hsa041400.27395733
100Acute myeloid leukemia_Homo sapiens_hsa052210.27266400
101Metabolic pathways_Homo sapiens_hsa011000.25734581
102RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.25651305
103Fatty acid metabolism_Homo sapiens_hsa012120.25238736
104Phenylalanine metabolism_Homo sapiens_hsa003600.24131519
105Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.23445644
106Arginine and proline metabolism_Homo sapiens_hsa003300.23193909
107Pentose and glucuronate interconversions_Homo sapiens_hsa000400.22998963
108Arachidonic acid metabolism_Homo sapiens_hsa005900.22696379
109Non-small cell lung cancer_Homo sapiens_hsa052230.22438788
110NOD-like receptor signaling pathway_Homo sapiens_hsa046210.22318532
111Lysine degradation_Homo sapiens_hsa003100.21939744
112Fat digestion and absorption_Homo sapiens_hsa049750.21891697
113Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.21344961
114mTOR signaling pathway_Homo sapiens_hsa041500.20565151
115Influenza A_Homo sapiens_hsa051640.20224417
116Tyrosine metabolism_Homo sapiens_hsa003500.20024072
117Huntingtons disease_Homo sapiens_hsa050160.19512415
118Shigellosis_Homo sapiens_hsa051310.19072814
119Caffeine metabolism_Homo sapiens_hsa002320.18846807
120Hematopoietic cell lineage_Homo sapiens_hsa046400.18763236
121Linoleic acid metabolism_Homo sapiens_hsa005910.18561321
122Type I diabetes mellitus_Homo sapiens_hsa049400.17887624
123Central carbon metabolism in cancer_Homo sapiens_hsa052300.16550827
124TGF-beta signaling pathway_Homo sapiens_hsa043500.14971590
125Notch signaling pathway_Homo sapiens_hsa043300.14275312
126SNARE interactions in vesicular transport_Homo sapiens_hsa041300.13963500
127Renin-angiotensin system_Homo sapiens_hsa046140.13261898
128Fatty acid degradation_Homo sapiens_hsa000710.11912885
129FoxO signaling pathway_Homo sapiens_hsa040680.10668285
130Leishmaniasis_Homo sapiens_hsa051400.09415181
131Pyruvate metabolism_Homo sapiens_hsa006200.08862641
132Vitamin digestion and absorption_Homo sapiens_hsa049770.08419682
133Basal cell carcinoma_Homo sapiens_hsa052170.08148450
134Chemical carcinogenesis_Homo sapiens_hsa052040.08021708
135alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.07354227

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