NT5CP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of acrosome reaction (GO:0060046)6.29406045
2histone H3-K9 demethylation (GO:0033169)6.03559796
3positive regulation of meiosis (GO:0045836)4.87528028
4regulation of cholesterol esterification (GO:0010872)4.81973437
5protein prenylation (GO:0018342)4.76416162
6prenylation (GO:0097354)4.76416162
7positive regulation of meiotic cell cycle (GO:0051446)4.62393713
8respiratory chain complex IV assembly (GO:0008535)4.55404246
9genitalia morphogenesis (GO:0035112)4.36077809
10serotonin metabolic process (GO:0042428)4.34041980
11cellular ketone body metabolic process (GO:0046950)4.13459974
12response to pheromone (GO:0019236)4.08668141
13water-soluble vitamin biosynthetic process (GO:0042364)4.02691225
14high-density lipoprotein particle remodeling (GO:0034375)4.01094028
15oocyte development (GO:0048599)3.93617732
16phospholipid efflux (GO:0033700)3.78588669
17xenobiotic catabolic process (GO:0042178)3.71413374
18indolalkylamine metabolic process (GO:0006586)3.68368899
19retinal cone cell development (GO:0046549)3.67529972
20ketone body metabolic process (GO:1902224)3.61363103
21indole-containing compound metabolic process (GO:0042430)3.60304063
22female gonad development (GO:0008585)3.60204659
23cellular response to ethanol (GO:0071361)3.58446895
24regulation of cytokine secretion involved in immune response (GO:0002739)3.56061178
25multicellular organism reproduction (GO:0032504)3.54210285
26cytochrome complex assembly (GO:0017004)3.48565112
27branched-chain amino acid catabolic process (GO:0009083)3.47586939
28plasma lipoprotein particle assembly (GO:0034377)3.45708739
29primary amino compound metabolic process (GO:1901160)3.42239166
30reverse cholesterol transport (GO:0043691)3.40451729
31cullin deneddylation (GO:0010388)3.36460980
32dolichol-linked oligosaccharide biosynthetic process (GO:0006488)3.30702560
33protein K6-linked ubiquitination (GO:0085020)3.28518930
34regulation of DNA endoreduplication (GO:0032875)3.27134845
35cholesterol biosynthetic process (GO:0006695)3.25686741
36phospholipid homeostasis (GO:0055091)3.25489982
37piRNA metabolic process (GO:0034587)3.22783078
38synapsis (GO:0007129)3.20708462
39regulation of meiosis I (GO:0060631)3.17792199
40negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804)3.15899187
41sterol biosynthetic process (GO:0016126)3.14859547
42protein-cofactor linkage (GO:0018065)3.14145115
43positive regulation of heterotypic cell-cell adhesion (GO:0034116)3.03788857
44cholesterol efflux (GO:0033344)3.01420745
45toxin transport (GO:1901998)3.00491261
46nucleobase catabolic process (GO:0046113)3.00411166
47plasma lipoprotein particle clearance (GO:0034381)2.99862541
48protein deneddylation (GO:0000338)2.99330973
49protein complex biogenesis (GO:0070271)2.97805154
50indolalkylamine catabolic process (GO:0046218)2.93218281
51tryptophan catabolic process (GO:0006569)2.93218281
52indole-containing compound catabolic process (GO:0042436)2.93218281
53peristalsis (GO:0030432)2.92905617
54proteasome assembly (GO:0043248)2.91496382
55epithelial cilium movement (GO:0003351)2.90920029
56DNA ligation (GO:0006266)2.90298986
57mitochondrial respiratory chain complex assembly (GO:0033108)2.90179939
58very-low-density lipoprotein particle assembly (GO:0034379)2.89208522
59aromatic amino acid family catabolic process (GO:0009074)2.88904281
60male meiosis I (GO:0007141)2.85573628
61tyrosine metabolic process (GO:0006570)2.85141183
62L-phenylalanine catabolic process (GO:0006559)2.84051031
63erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.84051031
64isoprenoid biosynthetic process (GO:0008299)2.82324895
65NADH dehydrogenase complex assembly (GO:0010257)2.80390737
66mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.80390737
67mitochondrial respiratory chain complex I assembly (GO:0032981)2.80390737
68negative regulation of Ras GTPase activity (GO:0034261)2.78924840
69mannosylation (GO:0097502)2.78825277
70regulation of heterotypic cell-cell adhesion (GO:0034114)2.77926163
71pyrimidine nucleobase catabolic process (GO:0006208)2.74472956
72epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.73154713
73protein-lipid complex assembly (GO:0065005)2.72700480
74tryptophan metabolic process (GO:0006568)2.72697629
75meiosis I (GO:0007127)2.72572813
76single fertilization (GO:0007338)2.71068574
77plasma lipoprotein particle remodeling (GO:0034369)2.70748039
78protein-lipid complex remodeling (GO:0034368)2.70748039
79macromolecular complex remodeling (GO:0034367)2.70748039
80intraciliary transport (GO:0042073)2.70411388
81DNA methylation involved in gamete generation (GO:0043046)2.70156646
82negative regulation of lipase activity (GO:0060192)2.67722385
83regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.64078417
84branched-chain amino acid metabolic process (GO:0009081)2.62105845
85regulation of helicase activity (GO:0051095)2.61110474
86establishment of protein localization to mitochondrial membrane (GO:0090151)2.58893295
87aldehyde catabolic process (GO:0046185)2.58747459
88negative regulation of hormone biosynthetic process (GO:0032353)2.58134758
89cellular response to gonadotropin stimulus (GO:0071371)2.57780582
90regulation of meiosis (GO:0040020)2.54321617
91lactate metabolic process (GO:0006089)2.52464906
92norepinephrine metabolic process (GO:0042415)2.51918345
93regulation of calcium ion-dependent exocytosis (GO:0017158)2.51612275
94negative regulation of DNA-dependent DNA replication (GO:2000104)2.51409762
95histone H3-K36 demethylation (GO:0070544)2.51403881
96kinetochore assembly (GO:0051382)2.50583953
97cilium movement (GO:0003341)2.50264450
98endocrine pancreas development (GO:0031018)2.49911945
99parental behavior (GO:0060746)2.49570479
100histone lysine demethylation (GO:0070076)2.49420064

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse5.02349331
2HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.99146096
3SALL1_21062744_ChIP-ChIP_HESCs_Human3.66574879
4GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse3.48857613
5GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.36520443
6VDR_22108803_ChIP-Seq_LS180_Human3.18517028
7KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.97072681
8FLI1_27457419_Chip-Seq_LIVER_Mouse2.53401846
9ZFP57_27257070_Chip-Seq_ESCs_Mouse2.49566517
10FUS_26573619_Chip-Seq_HEK293_Human2.49344936
11POU3F2_20337985_ChIP-ChIP_501MEL_Human2.46290378
12IGF1R_20145208_ChIP-Seq_DFB_Human2.43579744
13GABP_17652178_ChIP-ChIP_JURKAT_Human2.41261423
14ZNF274_21170338_ChIP-Seq_K562_Hela2.31350569
15BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.26319525
16TAF15_26573619_Chip-Seq_HEK293_Human2.23682811
17RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.16947463
18EST1_17652178_ChIP-ChIP_JURKAT_Human2.11581273
19P300_19829295_ChIP-Seq_ESCs_Human2.04486233
20EWS_26573619_Chip-Seq_HEK293_Human1.99415122
21BCAT_22108803_ChIP-Seq_LS180_Human1.99181654
22HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.98844142
23CTBP2_25329375_ChIP-Seq_LNCAP_Human1.94140741
24PCGF2_27294783_Chip-Seq_ESCs_Mouse1.80601212
25GBX2_23144817_ChIP-Seq_PC3_Human1.80048769
26EZH2_22144423_ChIP-Seq_EOC_Human1.74016375
27CREB1_15753290_ChIP-ChIP_HEK293T_Human1.72480324
28E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.70529297
29CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.69014361
30PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.64193850
31UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.61260424
32SMAD4_21799915_ChIP-Seq_A2780_Human1.60953635
33EGR1_23403033_ChIP-Seq_LIVER_Mouse1.57986633
34CTBP1_25329375_ChIP-Seq_LNCAP_Human1.56892606
35ELK1_19687146_ChIP-ChIP_HELA_Human1.55929373
36AR_25329375_ChIP-Seq_VCAP_Human1.55418662
37TCF4_22108803_ChIP-Seq_LS180_Human1.52583454
38ER_23166858_ChIP-Seq_MCF-7_Human1.51657725
39STAT3_23295773_ChIP-Seq_U87_Human1.50529233
40TOP2B_26459242_ChIP-Seq_MCF-7_Human1.47955840
41CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.46523004
42TCF4_23295773_ChIP-Seq_U87_Human1.42496927
43VDR_23849224_ChIP-Seq_CD4+_Human1.38998220
44NR3C1_21868756_ChIP-Seq_MCF10A_Human1.37436395
45SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.35486851
46CBP_20019798_ChIP-Seq_JUKART_Human1.35450854
47IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.35450854
48AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.34657616
49RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.34094681
50EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.32446338
51NANOG_19829295_ChIP-Seq_ESCs_Human1.27447732
52SOX2_19829295_ChIP-Seq_ESCs_Human1.27447732
53PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.27391368
54HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.26607590
55EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.26389714
56PRDM14_20953172_ChIP-Seq_ESCs_Human1.26328524
57SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.25007799
58SMAD3_21741376_ChIP-Seq_EPCs_Human1.23961585
59SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.23071387
60SRF_21415370_ChIP-Seq_HL-1_Mouse1.22976641
61PIAS1_25552417_ChIP-Seq_VCAP_Human1.22515638
62NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.20326236
63FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.19542884
64FLI1_21867929_ChIP-Seq_TH2_Mouse1.18987238
65SMAD3_21741376_ChIP-Seq_HESCs_Human1.16641799
66TP53_22573176_ChIP-Seq_HFKS_Human1.16018740
67JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.15905394
68NCOR_22424771_ChIP-Seq_293T_Human1.14425208
69STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.13039915
70AUTS2_25519132_ChIP-Seq_293T-REX_Human1.12687091
71CBX2_27304074_Chip-Seq_ESCs_Mouse1.12007871
72PADI4_21655091_ChIP-ChIP_MCF-7_Human1.11206938
73HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.10956214
74NOTCH1_21737748_ChIP-Seq_TLL_Human1.10883412
75KLF5_20875108_ChIP-Seq_MESCs_Mouse1.10511731
76ETS1_20019798_ChIP-Seq_JURKAT_Human1.10155576
77CDX2_22108803_ChIP-Seq_LS180_Human1.08367100
78FOXP3_21729870_ChIP-Seq_TREG_Human1.08323098
79CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.07766514
80SMAD4_21741376_ChIP-Seq_EPCs_Human1.07300112
81HTT_18923047_ChIP-ChIP_STHdh_Human1.05503286
82AR_20517297_ChIP-Seq_VCAP_Human1.04155634
83TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.03498081
84TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.03080831
85SALL4_22934838_ChIP-ChIP_CD34+_Human1.02611293
86GATA3_26560356_Chip-Seq_TH1_Human1.01814784
87OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.01622066
88RUNX2_22187159_ChIP-Seq_PCA_Human1.00921143
89SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.98267171
90FOXA1_25329375_ChIP-Seq_VCAP_Human0.97760009
91FOXA1_27270436_Chip-Seq_PROSTATE_Human0.97760009
92PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.96946411
93EZH2_27294783_Chip-Seq_NPCs_Mouse0.95354197
94PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.94223907
95FOXA1_21572438_ChIP-Seq_LNCaP_Human0.93552668
96RXR_22108803_ChIP-Seq_LS180_Human0.93051069
97TP63_19390658_ChIP-ChIP_HaCaT_Human0.92470837
98MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.92179336
99FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.91283516
100TAL1_26923725_Chip-Seq_HPCs_Mouse0.91109841

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009840_abnormal_foam_cell5.04835964
2MP0000372_irregular_coat_pigmentation4.89737450
3MP0003195_calcinosis3.76695865
4MP0008877_abnormal_DNA_methylation3.22507469
5MP0009780_abnormal_chondrocyte_physiolo3.05955296
6MP0001986_abnormal_taste_sensitivity2.92657497
7MP0005367_renal/urinary_system_phenotyp2.79472079
8MP0000516_abnormal_urinary_system2.79472079
9MP0008058_abnormal_DNA_repair2.79307784
10MP0000427_abnormal_hair_cycle2.56730350
11MP0003191_abnormal_cellular_cholesterol2.41963185
12MP0006292_abnormal_olfactory_placode2.39141611
13MP0005646_abnormal_pituitary_gland2.28950636
14MP0005360_urolithiasis2.16514634
15MP0002736_abnormal_nociception_after2.12574793
16MP0005220_abnormal_exocrine_pancreas2.08626587
17MP0010352_gastrointestinal_tract_polyps2.04515789
18MP0002160_abnormal_reproductive_system1.91378757
19MP0001502_abnormal_circadian_rhythm1.88072117
20MP0001968_abnormal_touch/_nociception1.79357042
21MP0005187_abnormal_penis_morphology1.74828208
22MP0006276_abnormal_autonomic_nervous1.73608702
23MP0003011_delayed_dark_adaptation1.70905664
24MP0003787_abnormal_imprinting1.64287493
25MP0004147_increased_porphyrin_level1.64149732
26MP0005084_abnormal_gallbladder_morpholo1.62337650
27MP0001501_abnormal_sleep_pattern1.56271220
28MP0003283_abnormal_digestive_organ1.53677252
29MP0001764_abnormal_homeostasis1.50329573
30MP0002102_abnormal_ear_morphology1.49391206
31MP0000647_abnormal_sebaceous_gland1.43441901
32MP0001929_abnormal_gametogenesis1.42211460
33MP0008872_abnormal_physiological_respon1.42193433
34MP0010094_abnormal_chromosome_stability1.41672192
35MP0005410_abnormal_fertilization1.40198797
36MP0002163_abnormal_gland_morphology1.37943441
37MP0000462_abnormal_digestive_system1.34198370
38MP0006072_abnormal_retinal_apoptosis1.32207293
39MP0003119_abnormal_digestive_system1.28997733
40MP0003718_maternal_effect1.27696013
41MP0003868_abnormal_feces_composition1.26634558
42MP0003656_abnormal_erythrocyte_physiolo1.24094157
43MP0001944_abnormal_pancreas_morphology1.23674920
44MP0009046_muscle_twitch1.20942666
45MP0005551_abnormal_eye_electrophysiolog1.19003660
46MP0001664_abnormal_digestion1.18755385
47MP0005174_abnormal_tail_pigmentation1.13883288
48MP0006054_spinal_hemorrhage1.12985338
49MP0002210_abnormal_sex_determination1.12885061
50MP0005389_reproductive_system_phenotype1.12819132
51MP0003806_abnormal_nucleotide_metabolis1.09325615
52MP0002876_abnormal_thyroid_physiology1.08040238
53MP0003136_yellow_coat_color1.07444962
54MP0002332_abnormal_exercise_endurance1.07021481
55MP0002277_abnormal_respiratory_mucosa1.06296975
56MP0009745_abnormal_behavioral_response1.05928702
57MP0010329_abnormal_lipoprotein_level1.05892861
58MP0005636_abnormal_mineral_homeostasis1.02292697
59MP0002693_abnormal_pancreas_physiology0.99797225
60MP0001243_abnormal_dermal_layer0.99097045
61MP0001299_abnormal_eye_distance/0.98065079
62MP0005075_abnormal_melanosome_morpholog0.97641087
63MP0003121_genomic_imprinting0.96060325
64MP0001119_abnormal_female_reproductive0.95279384
65MP0002272_abnormal_nervous_system0.94592740
66MP0002928_abnormal_bile_duct0.94379077
67MP0003786_premature_aging0.93890760
68MP0002837_dystrophic_cardiac_calcinosis0.93139102
69MP0000653_abnormal_sex_gland0.91087652
70MP0003698_abnormal_male_reproductive0.89540176
71MP0005647_abnormal_sex_gland0.89060232
72MP0003646_muscle_fatigue0.88762547
73MP0004381_abnormal_hair_follicle0.84690781
74MP0005376_homeostasis/metabolism_phenot0.82886248
75MP0005266_abnormal_metabolism0.82619811
76MP0002095_abnormal_skin_pigmentation0.82187578
77MP0002090_abnormal_vision0.81917491
78MP0004233_abnormal_muscle_weight0.81440400
79MP0003950_abnormal_plasma_membrane0.76495719
80MP0000631_abnormal_neuroendocrine_gland0.76305558
81MP0006036_abnormal_mitochondrial_physio0.76298122
82MP0003942_abnormal_urinary_system0.76167529
83MP0001666_abnormal_nutrient_absorption0.75278658
84MP0002557_abnormal_social/conspecific_i0.74419022
85MP0005164_abnormal_response_to0.73233981
86MP0000015_abnormal_ear_pigmentation0.71593127
87MP0002909_abnormal_adrenal_gland0.71478930
88MP0002734_abnormal_mechanical_nocicepti0.70547232
89MP0005253_abnormal_eye_physiology0.70316453
90MP0001145_abnormal_male_reproductive0.69826753
91MP0004510_myositis0.68768848
92MP0008007_abnormal_cellular_replicative0.66081624
93MP0003252_abnormal_bile_duct0.65309499
94MP0003699_abnormal_female_reproductive0.63499363
95MP0008004_abnormal_stomach_pH0.61516886
96MP0003943_abnormal_hepatobiliary_system0.61349131
97MP0004885_abnormal_endolymph0.61095896
98MP0009697_abnormal_copulation0.59775110
99MP0008875_abnormal_xenobiotic_pharmacok0.58963756
100MP0005670_abnormal_white_adipose0.58666793

Predicted human phenotypes

RankGene SetZ-score
1Spontaneous abortion (HP:0005268)6.41362079
2Steatorrhea (HP:0002570)4.31391331
3Chronic hepatic failure (HP:0100626)3.86145975
4Long clavicles (HP:0000890)3.85567045
5Neoplasm of the adrenal cortex (HP:0100641)3.76349598
6Neoplasm of the adrenal gland (HP:0100631)3.68973050
7Microglossia (HP:0000171)3.55215975
8Fat malabsorption (HP:0002630)3.43591863
9Hyperventilation (HP:0002883)3.29106101
10Pancreatic fibrosis (HP:0100732)3.19233988
11Upper limb muscle weakness (HP:0003484)3.14185480
12Aplasia/Hypoplasia of the tongue (HP:0010295)3.13099688
13Exocrine pancreatic insufficiency (HP:0001738)3.08632745
14Hypothermia (HP:0002045)2.97658970
15Pancreatic cysts (HP:0001737)2.93694159
16Hypobetalipoproteinemia (HP:0003563)2.93426445
17Aplasia/Hypoplasia of the tibia (HP:0005772)2.86680051
18Median cleft lip (HP:0000161)2.78209901
19Short tibia (HP:0005736)2.71122162
20Hypolipoproteinemia (HP:0010981)2.66915824
21Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.65897257
22Tetany (HP:0001281)2.56989618
23Tetraparesis (HP:0002273)2.55285789
24Hepatoblastoma (HP:0002884)2.54773914
25Abnormality of endocrine pancreas physiology (HP:0012093)2.54757417
26Abnormality of the pancreatic islet cells (HP:0006476)2.54757417
27Gaze-evoked nystagmus (HP:0000640)2.54661436
28True hermaphroditism (HP:0010459)2.53846984
29Ketoacidosis (HP:0001993)2.52780054
30Abnormality of the pubic bones (HP:0003172)2.45535276
31Posterior subcapsular cataract (HP:0007787)2.43099681
32Broad-based gait (HP:0002136)2.42285106
33Progressive macrocephaly (HP:0004481)2.42054455
34Increased CSF lactate (HP:0002490)2.38705612
35Hypomagnesemia (HP:0002917)2.36456955
36Acute necrotizing encephalopathy (HP:0006965)2.30121696
37Optic neuritis (HP:0100653)2.29103272
38Retrobulbar optic neuritis (HP:0100654)2.29103272
39Intrahepatic cholestasis (HP:0001406)2.26400780
40Hyperglycemia (HP:0003074)2.24317500
41Adrenal hypoplasia (HP:0000835)2.23417601
42Bifid tongue (HP:0010297)2.23307075
43Ketosis (HP:0001946)2.23187694
44Colon cancer (HP:0003003)2.21876652
45Bile duct proliferation (HP:0001408)2.17104194
46Abnormal biliary tract physiology (HP:0012439)2.17104194
47Acute encephalopathy (HP:0006846)2.15257664
48Hypoalphalipoproteinemia (HP:0003233)2.14842160
49Bell-shaped thorax (HP:0001591)2.12718927
50Abnormality of midbrain morphology (HP:0002418)2.11764172
51Molar tooth sign on MRI (HP:0002419)2.11764172
52Medial flaring of the eyebrow (HP:0010747)2.10792040
53Abnormality of the alveolar ridges (HP:0006477)2.08023695
54Metaphyseal dysplasia (HP:0100255)2.07567885
55Hyperinsulinemic hypoglycemia (HP:0000825)2.05104764
56Abnormality of dental color (HP:0011073)2.02779436
57Volvulus (HP:0002580)2.02635265
58Amelogenesis imperfecta (HP:0000705)2.02016169
59Increased serum lactate (HP:0002151)2.01411878
603-Methylglutaconic aciduria (HP:0003535)1.99819107
61Delayed CNS myelination (HP:0002188)1.94008843
62Hypoplastic nipples (HP:0002557)1.92237314
63Cystic liver disease (HP:0006706)1.91794024
64Astrocytoma (HP:0009592)1.91457895
65Abnormality of the astrocytes (HP:0100707)1.91457895
66Broad alveolar ridges (HP:0000187)1.90522879
67Abnormality of the level of lipoprotein cholesterol (HP:0010979)1.90437863
68Hepatocellular necrosis (HP:0001404)1.88810946
69Abnormal albumin level (HP:0012116)1.88717710
70Hypoalbuminemia (HP:0003073)1.88717710
71Short 1st metacarpal (HP:0010034)1.87535152
72Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.87535152
73Stomach cancer (HP:0012126)1.87516214
74Mitochondrial inheritance (HP:0001427)1.85810160
75Hypoplastic ischia (HP:0003175)1.85624825
76Pancreatic islet-cell hyperplasia (HP:0004510)1.85121804
77Abnormality of urine glucose concentration (HP:0011016)1.85047598
78Glycosuria (HP:0003076)1.85047598
79Wrist flexion contracture (HP:0001239)1.83489550
80Facial cleft (HP:0002006)1.82612963
81Attenuation of retinal blood vessels (HP:0007843)1.82554591
82Abnormality of the labia minora (HP:0012880)1.81573705
83Concave nail (HP:0001598)1.79845690
84Prominent supraorbital ridges (HP:0000336)1.79431983
85Abnormal mitochondria in muscle tissue (HP:0008316)1.78074320
86Large for gestational age (HP:0001520)1.77125018
87Popliteal pterygium (HP:0009756)1.75827826
88Bony spicule pigmentary retinopathy (HP:0007737)1.75009759
89Abnormality of alanine metabolism (HP:0010916)1.74819210
90Hyperalaninemia (HP:0003348)1.74819210
91Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.74819210
92Abnormality of the ischium (HP:0003174)1.74352216
93Occipital encephalocele (HP:0002085)1.73986734
94Abnormality of aspartate family amino acid metabolism (HP:0010899)1.73122375
95Hypoglycemic seizures (HP:0002173)1.72673953
96Abnormal delivery (HP:0001787)1.71033693
97Hepatic necrosis (HP:0002605)1.70997503
98Abnormality of methionine metabolism (HP:0010901)1.70971822
99Tubulointerstitial fibrosis (HP:0005576)1.70644231
100Cerebral edema (HP:0002181)1.70165657

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK5.69930438
2MAP2K63.55063939
3PDK23.18655450
4MAP4K23.13433536
5ACVR1B3.10893540
6BMPR1B2.56351848
7STK162.55725374
8STK392.42254617
9NUAK12.20915755
10FGFR21.95601431
11PNCK1.94578768
12MST41.92189288
13BRSK21.92012164
14NLK1.86643227
15EPHA31.57663187
16MAP3K41.57083151
17MAP3K121.56353692
18FER1.48494744
19TRIM281.47829744
20MAP3K21.43356470
21TNIK1.40311295
22RPS6KB21.37141249
23CAMKK21.35199947
24CSNK1G11.31068510
25WNK41.23379009
26MAP2K41.21025220
27EIF2AK31.19974836
28ZAK1.16986649
29VRK21.12272439
30PBK1.08193221
31ERBB31.07518227
32MAP2K31.05131965
33BUB11.04436215
34MYLK0.99885649
35CASK0.97573720
36MAPK130.93110849
37DYRK20.90735269
38PLK30.88658125
39CDK190.87197348
40PLK20.86994280
41WNK30.86915865
42PINK10.85791376
43OXSR10.85363588
44TGFBR10.84885730
45MAP3K60.84837050
46TRPM70.83630082
47PAK30.81870474
48BCKDK0.81130401
49MAP2K70.78393803
50GRK10.78021209
51PLK40.76440317
52CSNK1G30.75141852
53PRKCE0.74448401
54MAP3K50.71955531
55MINK10.69232435
56CSNK1G20.67984348
57NTRK30.66962760
58VRK10.64620984
59RPS6KB10.64060009
60TIE10.63750476
61CSNK1A1L0.62836308
62PRKCG0.62625608
63MAPKAPK50.62312965
64STK38L0.60213918
65ADRBK20.56892914
66DAPK20.56074149
67ADRBK10.55292045
68PRKCQ0.53614241
69TESK20.52663254
70MELK0.50857953
71MAPKAPK30.50537649
72WEE10.48796390
73PTK2B0.47280761
74ICK0.47182963
75PRKD30.46407783
76PKN10.45817980
77DDR20.44886222
78LIMK10.44484111
79TAOK30.41593759
80PRKACB0.41575081
81BMPR20.41396319
82TEC0.40775896
83MAPK110.39842201
84PHKG10.39338920
85PHKG20.39338920
86FGFR30.39305424
87ROCK10.39150911
88SCYL20.38749483
89EIF2AK10.35225460
90PASK0.35165701
91PRKAA10.34953516
92INSRR0.34738685
93PRKCZ0.34067459
94WNK10.33737118
95CSNK1D0.33591727
96PRKCI0.32408050
97CHEK10.31898327
98YES10.31808145
99PLK10.31616996
100CSNK1A10.31206854

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000724.51485719
2Terpenoid backbone biosynthesis_Homo sapiens_hsa009003.61033373
3Vitamin B6 metabolism_Homo sapiens_hsa007503.38907532
4Butanoate metabolism_Homo sapiens_hsa006503.19881270
5Maturity onset diabetes of the young_Homo sapiens_hsa049502.84246044
6Non-homologous end-joining_Homo sapiens_hsa034502.36171275
7Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.32725120
8Propanoate metabolism_Homo sapiens_hsa006402.30756697
9Protein export_Homo sapiens_hsa030602.23409109
10Sulfur metabolism_Homo sapiens_hsa009202.13882669
11Steroid biosynthesis_Homo sapiens_hsa001002.11206634
12RNA polymerase_Homo sapiens_hsa030202.02395125
13Primary bile acid biosynthesis_Homo sapiens_hsa001201.99827384
14Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.89883782
15Tryptophan metabolism_Homo sapiens_hsa003801.89369233
16Fatty acid metabolism_Homo sapiens_hsa012121.86846594
17Fatty acid elongation_Homo sapiens_hsa000621.83885516
18Fatty acid biosynthesis_Homo sapiens_hsa000611.82506077
19Basal transcription factors_Homo sapiens_hsa030221.79347557
20Selenocompound metabolism_Homo sapiens_hsa004501.72328202
21Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.68565442
22Proteasome_Homo sapiens_hsa030501.62113321
23Circadian rhythm_Homo sapiens_hsa047101.59249444
24Folate biosynthesis_Homo sapiens_hsa007901.59033236
25Fat digestion and absorption_Homo sapiens_hsa049751.55510983
26Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.47270909
27Homologous recombination_Homo sapiens_hsa034401.42017036
28Oxidative phosphorylation_Homo sapiens_hsa001901.32784949
29Fanconi anemia pathway_Homo sapiens_hsa034601.26450551
30Pentose and glucuronate interconversions_Homo sapiens_hsa000401.24709088
31Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.19194194
32One carbon pool by folate_Homo sapiens_hsa006701.12998103
33Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.12482082
34Dorso-ventral axis formation_Homo sapiens_hsa043201.11791237
35Regulation of autophagy_Homo sapiens_hsa041401.11699814
36Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.09914796
37Phototransduction_Homo sapiens_hsa047441.09100412
38Parkinsons disease_Homo sapiens_hsa050121.07944562
39Vitamin digestion and absorption_Homo sapiens_hsa049771.07474116
40Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.05591967
41Peroxisome_Homo sapiens_hsa041461.03754166
42Base excision repair_Homo sapiens_hsa034101.03718791
43Steroid hormone biosynthesis_Homo sapiens_hsa001401.02629569
44Fatty acid degradation_Homo sapiens_hsa000710.96349230
45Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.96130715
46Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.96099484
47Retinol metabolism_Homo sapiens_hsa008300.93499187
48Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.90780892
49N-Glycan biosynthesis_Homo sapiens_hsa005100.90344804
50Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.89900927
51Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.88204732
52Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.87227599
53Chemical carcinogenesis_Homo sapiens_hsa052040.86597469
54Insulin secretion_Homo sapiens_hsa049110.85569853
55Purine metabolism_Homo sapiens_hsa002300.84866120
56PPAR signaling pathway_Homo sapiens_hsa033200.84713087
57Metabolic pathways_Homo sapiens_hsa011000.77223583
58Huntingtons disease_Homo sapiens_hsa050160.76475256
59Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.73523493
60Pyruvate metabolism_Homo sapiens_hsa006200.73221863
61Pyrimidine metabolism_Homo sapiens_hsa002400.72944803
62Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.70768670
63Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.69750104
64Cysteine and methionine metabolism_Homo sapiens_hsa002700.69351764
65RNA degradation_Homo sapiens_hsa030180.67037147
66Linoleic acid metabolism_Homo sapiens_hsa005910.66222366
67Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.66104066
68Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.65820716
692-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.63367979
70beta-Alanine metabolism_Homo sapiens_hsa004100.62227807
71Glutathione metabolism_Homo sapiens_hsa004800.59803777
72Glycerolipid metabolism_Homo sapiens_hsa005610.58670061
73Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.57336101
74Circadian entrainment_Homo sapiens_hsa047130.56575309
75RNA transport_Homo sapiens_hsa030130.55745926
76Collecting duct acid secretion_Homo sapiens_hsa049660.52821824
77alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.51601945
78Complement and coagulation cascades_Homo sapiens_hsa046100.49947626
79GABAergic synapse_Homo sapiens_hsa047270.45106136
80Starch and sucrose metabolism_Homo sapiens_hsa005000.44768351
81Olfactory transduction_Homo sapiens_hsa047400.43452086
82Fructose and mannose metabolism_Homo sapiens_hsa000510.43447184
83Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.42065791
84Dopaminergic synapse_Homo sapiens_hsa047280.40152105
85Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.38891764
86Carbon metabolism_Homo sapiens_hsa012000.38258821
87Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.36563796
88Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.35790469
89Mineral absorption_Homo sapiens_hsa049780.34351911
90Alzheimers disease_Homo sapiens_hsa050100.34319270
91Tyrosine metabolism_Homo sapiens_hsa003500.31546277
92Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.29122619
93Mismatch repair_Homo sapiens_hsa034300.27759518
94ABC transporters_Homo sapiens_hsa020100.27631016
95Serotonergic synapse_Homo sapiens_hsa047260.24900250
96Bile secretion_Homo sapiens_hsa049760.23476947
97Oocyte meiosis_Homo sapiens_hsa041140.22524915
98Ether lipid metabolism_Homo sapiens_hsa005650.22484017
99Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.22022066
100Sphingolipid metabolism_Homo sapiens_hsa006000.19878045

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »