NT5DC2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)5.69337143
2DNA strand elongation involved in DNA replication (GO:0006271)4.69599968
3planar cell polarity pathway involved in neural tube closure (GO:0090179)4.44742916
4DNA strand elongation (GO:0022616)4.44442155
5DNA replication initiation (GO:0006270)4.26872828
6protein localization to kinetochore (GO:0034501)4.26394079
7telomere maintenance via semi-conservative replication (GO:0032201)4.13810584
8regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)4.05831847
9negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.94328240
10DNA replication-dependent nucleosome assembly (GO:0006335)3.92048976
11DNA replication-dependent nucleosome organization (GO:0034723)3.92048976
12paraxial mesoderm development (GO:0048339)3.91882394
13viral transcription (GO:0019083)3.87041091
14folic acid-containing compound biosynthetic process (GO:0009396)3.86564936
15convergent extension (GO:0060026)3.85610501
16ribosomal small subunit assembly (GO:0000028)3.79431625
17translational termination (GO:0006415)3.76992370
18mitotic nuclear envelope disassembly (GO:0007077)3.74948983
19formation of translation preinitiation complex (GO:0001731)3.74393935
20negative regulation of RNA splicing (GO:0033119)3.65886525
21protein localization to chromosome, centromeric region (GO:0071459)3.62326791
22peptidyl-arginine omega-N-methylation (GO:0035247)3.62035017
23telomere maintenance via recombination (GO:0000722)3.59689703
24mitotic recombination (GO:0006312)3.54924567
25IMP biosynthetic process (GO:0006188)3.53862140
26translational elongation (GO:0006414)3.48502347
27nuclear pore organization (GO:0006999)3.48433267
28nuclear envelope disassembly (GO:0051081)3.47478424
29membrane disassembly (GO:0030397)3.47478424
30heterochromatin organization (GO:0070828)3.46942713
31maturation of SSU-rRNA (GO:0030490)3.46689529
32regulation of gene silencing by RNA (GO:0060966)3.45512791
33regulation of posttranscriptional gene silencing (GO:0060147)3.45512791
34regulation of gene silencing by miRNA (GO:0060964)3.45512791
35mitotic metaphase plate congression (GO:0007080)3.42751930
36mitotic sister chromatid segregation (GO:0000070)3.41358462
37negative regulation of mRNA processing (GO:0050686)3.40805972
38pre-miRNA processing (GO:0031054)3.39616027
39DNA replication checkpoint (GO:0000076)3.38821388
40sister chromatid segregation (GO:0000819)3.37675220
41nucleobase biosynthetic process (GO:0046112)3.36889019
42L-serine metabolic process (GO:0006563)3.33969507
43translational initiation (GO:0006413)3.33430425
44nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.32718155
45establishment of integrated proviral latency (GO:0075713)3.32113244
46regulation of mammary gland epithelial cell proliferation (GO:0033599)3.31845384
47nucleotide-excision repair, DNA gap filling (GO:0006297)3.28557163
48DNA duplex unwinding (GO:0032508)3.27619405
49mitotic chromosome condensation (GO:0007076)3.27515010
50SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.27374932
51DNA geometric change (GO:0032392)3.26212645
52telomere maintenance via telomere lengthening (GO:0010833)3.25501269
53cochlea morphogenesis (GO:0090103)3.24492307
54regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.24121361
55protein retention in ER lumen (GO:0006621)3.20691972
56protein complex localization (GO:0031503)3.20293899
57protein targeting to ER (GO:0045047)3.17575585
58cotranslational protein targeting to membrane (GO:0006613)3.16928206
59regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.16885505
60outer ear morphogenesis (GO:0042473)3.15999004
61kinetochore organization (GO:0051383)3.12291954
62proline biosynthetic process (GO:0006561)3.11854109
63chromatin remodeling at centromere (GO:0031055)3.11729751
64nuclear pore complex assembly (GO:0051292)3.11575064
65histone arginine methylation (GO:0034969)3.11399420
66Wnt signaling pathway, planar cell polarity pathway (GO:0060071)3.10513913
67maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.10390808
68dosage compensation (GO:0007549)3.09500656
69spliceosomal snRNP assembly (GO:0000387)3.09176112
70CENP-A containing nucleosome assembly (GO:0034080)3.07932209
71metaphase plate congression (GO:0051310)3.07912614
72translesion synthesis (GO:0019985)3.07627968
73RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)3.06575757
74mRNA splicing, via spliceosome (GO:0000398)3.06575757
75IMP metabolic process (GO:0046040)3.05402921
76peptidyl-arginine methylation (GO:0018216)3.05215231
77peptidyl-arginine N-methylation (GO:0035246)3.05215231
78RNA splicing, via transesterification reactions (GO:0000375)3.04558142
79DNA replication-independent nucleosome assembly (GO:0006336)3.04451549
80DNA replication-independent nucleosome organization (GO:0034724)3.04451549
81regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.03373750
82negative regulation of mRNA metabolic process (GO:1903312)3.00817594
83establishment of protein localization to endoplasmic reticulum (GO:0072599)3.00701837
84cellular protein complex disassembly (GO:0043624)2.98573728
85regulation of translational fidelity (GO:0006450)2.97318578
86spliceosomal complex assembly (GO:0000245)2.95612613
87notochord development (GO:0030903)2.94754088
88ribosomal large subunit biogenesis (GO:0042273)2.94700286
89nucleosome disassembly (GO:0006337)2.94331512
90protein-DNA complex disassembly (GO:0032986)2.94331512
91viral life cycle (GO:0019058)2.94297834
92negative regulation of chromosome segregation (GO:0051985)2.94219359
93protein complex disassembly (GO:0043241)2.94050283
94regulation of establishment of planar polarity (GO:0090175)2.92664958
95chromatin assembly or disassembly (GO:0006333)2.92330386
96termination of RNA polymerase II transcription (GO:0006369)2.92269054
97ribosomal small subunit biogenesis (GO:0042274)2.90535559
98protein localization to endoplasmic reticulum (GO:0070972)2.89675558
99negative regulation of mitotic sister chromatid separation (GO:2000816)2.89118680
100negative regulation of mitotic sister chromatid segregation (GO:0033048)2.89118680
101negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.89118680
102negative regulation of sister chromatid segregation (GO:0033046)2.89118680
103spindle assembly checkpoint (GO:0071173)2.87481629
104regulation of sister chromatid cohesion (GO:0007063)2.87470716
105mitotic spindle assembly checkpoint (GO:0007094)2.86870593
106establishment of chromosome localization (GO:0051303)2.83361659
107regulation of chromosome segregation (GO:0051983)2.82533286
108purine nucleobase biosynthetic process (GO:0009113)2.81857642
109spliceosomal tri-snRNP complex assembly (GO:0000244)2.81452440
110chromatin assembly (GO:0031497)2.79353688
111spindle checkpoint (GO:0031577)2.79341560
1123-UTR-mediated mRNA stabilization (GO:0070935)2.78891143
113negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.78783691
114ATP-dependent chromatin remodeling (GO:0043044)2.78701514
115COPI coating of Golgi vesicle (GO:0048205)2.77444501
116Golgi transport vesicle coating (GO:0048200)2.77444501
117regulation of spindle organization (GO:0090224)2.76823702
118mitotic spindle checkpoint (GO:0071174)2.76295503
119cellular protein complex localization (GO:0034629)2.74389422
120G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.65824000
121non-canonical Wnt signaling pathway (GO:0035567)2.62960368
122regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.58076937
123establishment of apical/basal cell polarity (GO:0035089)2.56708774
124protein maturation by protein folding (GO:0022417)2.51701446
125mitotic sister chromatid cohesion (GO:0007064)2.49659877
126basement membrane organization (GO:0071711)2.49424589
127chromosome condensation (GO:0030261)2.46335655
128regulation of NFAT protein import into nucleus (GO:0051532)2.46194520
129mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)2.44291150
130adherens junction assembly (GO:0034333)2.41041917
131positive regulation of SMAD protein import into nucleus (GO:0060391)2.40925482
132chondrocyte proliferation (GO:0035988)2.35616791
133negative regulation of chondrocyte differentiation (GO:0032331)2.35063624
134neuron projection extension involved in neuron projection guidance (GO:1902284)2.32562501
135axon extension involved in axon guidance (GO:0048846)2.32562501
136establishment of viral latency (GO:0019043)2.32139321
137negative regulation of DNA repair (GO:0045738)2.29589898
138positive regulation of DNA-dependent DNA replication (GO:2000105)2.28960254
139positive regulation of chromosome segregation (GO:0051984)2.28848435
140ventricular cardiac muscle cell development (GO:0055015)2.28290481
141regulation of heart morphogenesis (GO:2000826)2.27710236
142DNA synthesis involved in DNA repair (GO:0000731)2.27380108
143positive regulation of G2/M transition of mitotic cell cycle (GO:0010971)2.26009685
144positive regulation of cell cycle G2/M phase transition (GO:1902751)2.26009685
145hippo signaling (GO:0035329)2.24755711
146dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.23764433
147DNA topological change (GO:0006265)2.23714806
148neural tube development (GO:0021915)2.23307486
149RNA stabilization (GO:0043489)2.22493492
150mRNA stabilization (GO:0048255)2.22493492
151regulation of mitotic spindle organization (GO:0060236)2.20813376
152proline metabolic process (GO:0006560)2.20288974
153regulation of early endosome to late endosome transport (GO:2000641)2.19633442
154serine family amino acid biosynthetic process (GO:0009070)2.17747619
155nucleobase-containing small molecule interconversion (GO:0015949)2.17665780
156gap junction assembly (GO:0016264)2.16602475
157atrial septum morphogenesis (GO:0060413)2.16058628
158regulation of stem cell maintenance (GO:2000036)2.16049177
159bone trabecula formation (GO:0060346)2.15956852
160maternal placenta development (GO:0001893)2.15935812

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.04080477
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.82350989
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.29081220
4* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.97883463
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.75503866
6FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.31130356
7MYC_19079543_ChIP-ChIP_MESCs_Mouse3.06824396
8* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.77805557
9MYC_18358816_ChIP-ChIP_MESCs_Mouse2.62643078
10XRN2_22483619_ChIP-Seq_HELA_Human2.48110676
11EGR1_19374776_ChIP-ChIP_THP-1_Human2.47522420
12NELFA_20434984_ChIP-Seq_ESCs_Mouse2.36736175
13EST1_17652178_ChIP-ChIP_JURKAT_Human2.34782025
14KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.33846936
15HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.28188515
16AR_21909140_ChIP-Seq_LNCAP_Human2.25175177
17ETS1_20019798_ChIP-Seq_JURKAT_Human2.16699311
18CREB1_15753290_ChIP-ChIP_HEK293T_Human2.13068821
19E2F1_21310950_ChIP-Seq_MCF-7_Human2.10887794
20MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.07949736
21MYC_22102868_ChIP-Seq_BL_Human2.05180583
22* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.95230540
23GABP_17652178_ChIP-ChIP_JURKAT_Human1.94394210
24CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.90188075
25TTF2_22483619_ChIP-Seq_HELA_Human1.88847333
26E2F1_18555785_ChIP-Seq_MESCs_Mouse1.87192878
27JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.85823165
28CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.83445333
29TP63_19390658_ChIP-ChIP_HaCaT_Human1.82477699
30MYCN_18555785_ChIP-Seq_MESCs_Mouse1.80864525
31KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.76410566
32ZFX_18555785_ChIP-Seq_MESCs_Mouse1.73984434
33CIITA_25753668_ChIP-Seq_RAJI_Human1.70139406
34DCP1A_22483619_ChIP-Seq_HELA_Human1.68663675
35RBPJ_22232070_ChIP-Seq_NCS_Mouse1.65555248
36TP63_17297297_ChIP-ChIP_HaCaT_Human1.64413646
37RARG_19884340_ChIP-ChIP_MEFs_Mouse1.64100854
38NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.64024459
39THAP11_20581084_ChIP-Seq_MESCs_Mouse1.62336307
40POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.61010577
41WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.60272973
42* GABP_19822575_ChIP-Seq_HepG2_Human1.59913140
43VDR_23849224_ChIP-Seq_CD4+_Human1.56767074
44ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.56085971
45ELF1_17652178_ChIP-ChIP_JURKAT_Human1.55203823
46HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.54814926
47ZNF263_19887448_ChIP-Seq_K562_Human1.54703108
48PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.53960315
49CLOCK_20551151_ChIP-Seq_293T_Human1.53802124
50SOX2_18555785_ChIP-Seq_MESCs_Mouse1.52883646
51TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.52568068
52NANOG_18555785_ChIP-Seq_MESCs_Mouse1.52479675
53PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.52444755
54FOXP3_21729870_ChIP-Seq_TREG_Human1.52133332
55ESR1_15608294_ChIP-ChIP_MCF-7_Human1.51941550
56KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.51811920
57TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.48858827
58YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.47377304
59ERG_21242973_ChIP-ChIP_JURKAT_Human1.46930841
60VDR_21846776_ChIP-Seq_THP-1_Human1.44553554
61ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.43132679
62SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.42934795
63* LXR_22292898_ChIP-Seq_THP-1_Human1.41823514
64EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.41111983
65TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.40743623
66* RACK7_27058665_Chip-Seq_MCF-7_Human1.39464520
67SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.38666117
68KDM5A_27292631_Chip-Seq_BREAST_Human1.36910869
69POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.36654239
70TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.33902050
71* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.29397626
72DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.27648279
73POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.27327453
74P300_27058665_Chip-Seq_ZR-75-30cells_Human1.25037112
75RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.24616926
76KDM2B_26808549_Chip-Seq_K562_Human1.23491357
77UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.22637250
78ELK1_19687146_ChIP-ChIP_HELA_Human1.21669934
79KLF4_18555785_ChIP-Seq_MESCs_Mouse1.20445529
80SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.20191062
81* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.19463997
82TFEB_21752829_ChIP-Seq_HELA_Human1.18081627
83NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.16832638
84PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.16662622
85E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.16643699
86KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.15937101
87FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.15919995
88PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.15768397
89NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.15305457
90KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.15145664
91CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.14790335
92SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.14780010
93CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.13396536
94HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.13347303
95TET1_21451524_ChIP-Seq_MESCs_Mouse1.13291284
96TCF3_18692474_ChIP-Seq_MEFs_Mouse1.13107145
97NANOG_21062744_ChIP-ChIP_HESCs_Human1.12547898
98TRIM28_19339689_ChIP-ChIP_MESCs_Mouse1.10515080
99STAT3_1855785_ChIP-Seq_MESCs_Mouse1.10235301
100KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.10021208
101YY1_21170310_ChIP-Seq_MESCs_Mouse1.08786013
102ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.08166127
103HOXB4_20404135_ChIP-ChIP_EML_Mouse1.07978484
104TRIM28_21343339_ChIP-Seq_HEK293_Human1.05553669
105SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.05000373
106FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.03442213
107ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.02672990
108TP53_20018659_ChIP-ChIP_R1E_Mouse1.01750443
109SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.01061769
110* SOX2_18692474_ChIP-Seq_MEFs_Mouse1.00766758
111THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.00485123
112PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.98675176
113ERG_20887958_ChIP-Seq_HPC-7_Mouse0.97990083
114SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.97865261
115TP53_22127205_ChIP-Seq_IMR90_Human0.97655873
116ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.97293586
117CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.96391401
118NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.95856355
119KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.95330194
120KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.95330194
121KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.95330194
122ZFP281_18757296_ChIP-ChIP_E14_Mouse0.94026295
123HIF1A_21447827_ChIP-Seq_MCF-7_Human0.93518900
124NANOG_16153702_ChIP-ChIP_HESCs_Human0.93181764
125HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.91573525
126CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.91340335
127* TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.90550245
128CHD1_26751641_Chip-Seq_LNCaP_Human0.90351952
129PADI4_21655091_ChIP-ChIP_MCF-7_Human0.90200334
130OCT4_18692474_ChIP-Seq_MEFs_Mouse0.90089895
131MYC_18940864_ChIP-ChIP_HL60_Human0.89401588
132ELK3_25401928_ChIP-Seq_HUVEC_Human0.89365482
133BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.87979001
134HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.87870318
135SOX2_16153702_ChIP-ChIP_HESCs_Human0.87765274

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003123_paternal_imprinting3.73855149
2MP0003693_abnormal_embryo_hatching3.45346841
3MP0010030_abnormal_orbit_morphology3.33697036
4MP0010094_abnormal_chromosome_stability3.29197142
5MP0004957_abnormal_blastocyst_morpholog3.26246372
6MP0003111_abnormal_nucleus_morphology3.24864259
7MP0003077_abnormal_cell_cycle3.05611894
8MP0008057_abnormal_DNA_replication2.47391698
9MP0008007_abnormal_cellular_replicative2.39651910
10MP0003121_genomic_imprinting2.39590003
11MP0000537_abnormal_urethra_morphology2.28942848
12MP0009053_abnormal_anal_canal2.24611965
13MP0003122_maternal_imprinting2.23647005
14MP0008932_abnormal_embryonic_tissue2.19702161
15MP0001730_embryonic_growth_arrest2.12159470
16MP0003705_abnormal_hypodermis_morpholog2.01134496
17MP0000566_synostosis1.99003272
18MP0003567_abnormal_fetal_cardiomyocyte1.97297946
19MP0004858_abnormal_nervous_system1.97110436
20MP0008058_abnormal_DNA_repair1.93984572
21MP0000350_abnormal_cell_proliferation1.92254434
22MP0004197_abnormal_fetal_growth/weight/1.87734500
23MP0010352_gastrointestinal_tract_polyps1.84025475
24MP0005076_abnormal_cell_differentiation1.81485581
25MP0003119_abnormal_digestive_system1.77647173
26MP0002085_abnormal_embryonic_tissue1.76658143
27MP0001697_abnormal_embryo_size1.75309455
28MP0001672_abnormal_embryogenesis/_devel1.74872183
29MP0005380_embryogenesis_phenotype1.74872183
30MP0003283_abnormal_digestive_organ1.72708663
31MP0002084_abnormal_developmental_patter1.72429695
32MP0001293_anophthalmia1.61862281
33MP0003984_embryonic_growth_retardation1.61844568
34MP0002088_abnormal_embryonic_growth/wei1.60315504
35MP0001346_abnormal_lacrimal_gland1.56710470
36MP0003890_abnormal_embryonic-extraembry1.52576948
37MP0002080_prenatal_lethality1.52044015
38MP0000049_abnormal_middle_ear1.51734026
39MP0002697_abnormal_eye_size1.48059182
40MP0010307_abnormal_tumor_latency1.47964098
41MP0009672_abnormal_birth_weight1.47550898
42MP0006054_spinal_hemorrhage1.44962981
43MP0003385_abnormal_body_wall1.44058356
44MP0002938_white_spotting1.43535510
45MP0002086_abnormal_extraembryonic_tissu1.42990822
46MP0008877_abnormal_DNA_methylation1.42242204
47MP0003942_abnormal_urinary_system1.42039313
48MP0003315_abnormal_perineum_morphology1.40678863
49MP0004133_heterotaxia1.38062148
50MP0000428_abnormal_craniofacial_morphol1.38041009
51MP0003941_abnormal_skin_development1.36090722
52MP0001299_abnormal_eye_distance/1.36004585
53MP0003937_abnormal_limbs/digits/tail_de1.34118676
54MP0010368_abnormal_lymphatic_system1.33180339
55MP0002089_abnormal_postnatal_growth/wei1.32791369
56MP0000762_abnormal_tongue_morphology1.29087640
57MP0002653_abnormal_ependyma_morphology1.27939904
58MP0003115_abnormal_respiratory_system1.27595680
59MP0002111_abnormal_tail_morphology1.25039346
60MP0009379_abnormal_foot_pigmentation1.23140926
61MP0002932_abnormal_joint_morphology1.20317140
62MP0000678_abnormal_parathyroid_gland1.18708600
63MP0002282_abnormal_trachea_morphology1.16471334
64MP0002249_abnormal_larynx_morphology1.15681974
65MP0004185_abnormal_adipocyte_glucose1.15478045
66MP0003935_abnormal_craniofacial_develop1.14671235
67MP0008789_abnormal_olfactory_epithelium1.11623512
68MP0002092_abnormal_eye_morphology1.09990631
69MP0009703_decreased_birth_body1.09451259
70MP0001286_abnormal_eye_development1.09404107
71MP0004808_abnormal_hematopoietic_stem1.06637319
72MP0000313_abnormal_cell_death1.04917757
73MP0004233_abnormal_muscle_weight1.04202045
74MP0000490_abnormal_crypts_of1.02921233
75MP0000733_abnormal_muscle_development1.01920053
76MP0009278_abnormal_bone_marrow1.01696286
77MP0005409_darkened_coat_color0.99529155
78MP0008438_abnormal_cutaneous_collagen0.99456431
79MP0004272_abnormal_basement_membrane0.99447391
80MP0009384_cardiac_valve_regurgitation0.99432502
81MP0005197_abnormal_uvea_morphology0.98951255
82MP0001915_intracranial_hemorrhage0.98029190
83MP0003279_aneurysm0.95426636
84MP0002396_abnormal_hematopoietic_system0.95377692
85MP0003755_abnormal_palate_morphology0.94947978
86MP0003786_premature_aging0.92353844
87MP0000432_abnormal_head_morphology0.92018497
88MP0002116_abnormal_craniofacial_bone0.91888915
89MP0000003_abnormal_adipose_tissue0.91808199
90MP0002751_abnormal_autonomic_nervous0.91543114
91MP0002925_abnormal_cardiovascular_devel0.90977294
92MP0009250_abnormal_appendicular_skeleto0.90198393
93MP0002060_abnormal_skin_morphology0.89933144
94MP0000534_abnormal_ureter_morphology0.88682637
95MP0001849_ear_inflammation0.88096879
96MP0000767_abnormal_smooth_muscle0.87055386
97MP0003861_abnormal_nervous_system0.86618269
98MP0003566_abnormal_cell_adhesion0.85551177
99MP0006292_abnormal_olfactory_placode0.85132412
100MP0005623_abnormal_meninges_morphology0.84170293
101MP0002234_abnormal_pharynx_morphology0.83673107
102MP0003938_abnormal_ear_development0.83146632
103MP0002114_abnormal_axial_skeleton0.83047207
104MP0000579_abnormal_nail_morphology0.81436256
105MP0005187_abnormal_penis_morphology0.80699001
106MP0002019_abnormal_tumor_incidence0.80553634
107MP0001340_abnormal_eyelid_morphology0.79795105
108MP0003221_abnormal_cardiomyocyte_apopto0.79236733
109MP0002233_abnormal_nose_morphology0.78861295
110MP0000266_abnormal_heart_morphology0.78362592
111MP0005257_abnormal_intraocular_pressure0.76662755
112MP0000462_abnormal_digestive_system0.75960734
113MP0005503_abnormal_tendon_morphology0.75565723
114MP0002163_abnormal_gland_morphology0.75009902
115MP0002254_reproductive_system_inflammat0.74493668
116MP0000778_abnormal_nervous_system0.73963087
117MP0010630_abnormal_cardiac_muscle0.73392645
118MP0005023_abnormal_wound_healing0.70475251
119MP0002109_abnormal_limb_morphology0.70020628
120MP0005508_abnormal_skeleton_morphology0.66996970
121MP0002127_abnormal_cardiovascular_syste0.66432325
122MP0002877_abnormal_melanocyte_morpholog0.64389550
123MP0002081_perinatal_lethality0.64378696

Predicted human phenotypes

RankGene SetZ-score
1Premature rupture of membranes (HP:0001788)4.45701187
2Reticulocytopenia (HP:0001896)3.72794651
3Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.67739039
4Short 4th metacarpal (HP:0010044)3.67739039
5Renal duplication (HP:0000075)3.61072615
6Colon cancer (HP:0003003)3.52750187
7Selective tooth agenesis (HP:0001592)3.47191564
8Abnormality of cells of the erythroid lineage (HP:0012130)3.09442285
9Medulloblastoma (HP:0002885)3.07644925
10Abnormal number of incisors (HP:0011064)2.95579613
11Abnormal number of erythroid precursors (HP:0012131)2.90582428
12Ulnar bowing (HP:0003031)2.89596474
13Ependymoma (HP:0002888)2.88450934
14Abnormality of dentin (HP:0010299)2.86745793
15Increased nuchal translucency (HP:0010880)2.85893681
16Abnormality of the 4th metacarpal (HP:0010012)2.80768626
17Broad distal phalanx of finger (HP:0009836)2.64438929
18Genu recurvatum (HP:0002816)2.58186058
19Missing ribs (HP:0000921)2.57669434
20Atresia of the external auditory canal (HP:0000413)2.56288244
21Patellar aplasia (HP:0006443)2.53658565
22Hyperacusis (HP:0010780)2.47723639
23Disproportionate tall stature (HP:0001519)2.46648971
24Partial duplication of the phalanx of hand (HP:0009999)2.46382529
25Aplasia/Hypoplasia of the patella (HP:0006498)2.44873588
26Birth length less than 3rd percentile (HP:0003561)2.43504725
27Deviation of the thumb (HP:0009603)2.42583187
28Ankle contracture (HP:0006466)2.41707501
29Abnormal lung lobation (HP:0002101)2.41119823
30Degeneration of anterior horn cells (HP:0002398)2.40522659
31Abnormality of the anterior horn cell (HP:0006802)2.40522659
32Proximal placement of thumb (HP:0009623)2.38711028
33Coronal craniosynostosis (HP:0004440)2.38241293
34Short 5th finger (HP:0009237)2.33987518
35Partial duplication of thumb phalanx (HP:0009944)2.31734739
36Slender long bone (HP:0003100)2.28889552
37Neonatal short-limb short stature (HP:0008921)2.25872655
38Abnormality of the phalanges of the hallux (HP:0010057)2.24511664
39Biconcave vertebral bodies (HP:0004586)2.23580012
40Turricephaly (HP:0000262)2.23436854
41Broad metatarsal (HP:0001783)2.23221125
42Rhabdomyosarcoma (HP:0002859)2.22911818
43Protrusio acetabuli (HP:0003179)2.19501435
44Intestinal polyp (HP:0005266)2.19188023
45Aplasia/Hypoplasia of the sternum (HP:0006714)2.18183699
4611 pairs of ribs (HP:0000878)2.18023760
47Renovascular hypertension (HP:0100817)2.16044034
48Spinal rigidity (HP:0003306)2.11859788
49Fragile skin (HP:0001030)2.11307364
50Duplication of thumb phalanx (HP:0009942)2.10854252
51Intestinal polyposis (HP:0200008)2.10720048
52Neoplasm of the pancreas (HP:0002894)2.09999994
53Shallow orbits (HP:0000586)2.09438033
54Aplasia/Hypoplasia of the 5th finger (HP:0006262)2.09394748
55Broad thumb (HP:0011304)2.09193151
56Soft skin (HP:0000977)2.08979648
57Agnosia (HP:0010524)2.08876777
58Short middle phalanx of the 5th finger (HP:0004220)2.06597111
59Arnold-Chiari malformation (HP:0002308)2.05744161
60Neoplasm of striated muscle (HP:0009728)2.05330113
61Oral leukoplakia (HP:0002745)2.04539807
62Deviation of the hallux (HP:0010051)2.02547219
63Trismus (HP:0000211)2.01420669
64Breast hypoplasia (HP:0003187)2.00814040
65Meckel diverticulum (HP:0002245)2.00488964
66High pitched voice (HP:0001620)1.99986093
67High anterior hairline (HP:0009890)1.99119450
68Abnormality of the calcaneus (HP:0008364)1.98428529
69Overriding aorta (HP:0002623)1.97334710
70Astrocytoma (HP:0009592)1.93219732
71Abnormality of the astrocytes (HP:0100707)1.93219732
72Diastasis recti (HP:0001540)1.93018390
73Nephroblastoma (Wilms tumor) (HP:0002667)1.92777501
74Angiofibromas (HP:0010615)1.92080050
75Adenoma sebaceum (HP:0009720)1.92080050
76Aplasia/Hypoplasia of the sacrum (HP:0008517)1.92019027
77Blue sclerae (HP:0000592)1.91912332
78Abnormality of the ileum (HP:0001549)1.91486464
79Supernumerary spleens (HP:0009799)1.90895737
80Abnormality of the distal phalanx of the thumb (HP:0009617)1.90725443
81Tracheoesophageal fistula (HP:0002575)1.90237619
82Broad long bones (HP:0005622)1.90039057
83Thin ribs (HP:0000883)1.89995633
84Broad phalanges of the hand (HP:0009768)1.89951801
85Elfin facies (HP:0004428)1.89566859
86Absent thumb (HP:0009777)1.88823020
87Pallor (HP:0000980)1.88650159
88Hallux valgus (HP:0001822)1.88511771
89Embryonal renal neoplasm (HP:0011794)1.88423841
90Achilles tendon contracture (HP:0001771)1.88409431
91Macrocytic anemia (HP:0001972)1.87153048
92Ectopic kidney (HP:0000086)1.86405815
93Long palpebral fissure (HP:0000637)1.85847761
94Ovarian neoplasm (HP:0100615)1.85838924
95Abnormality of the fetal cardiovascular system (HP:0010948)1.85603498
96Abnormal umbilical cord blood vessels (HP:0011403)1.85603498
97Single umbilical artery (HP:0001195)1.85603498
98Chromsome breakage (HP:0040012)1.85580170
99Absent radius (HP:0003974)1.85071361
100Preauricular skin tag (HP:0000384)1.84275886
101Rib fusion (HP:0000902)1.83744232
102Broad palm (HP:0001169)1.83655833
103Skin tags (HP:0010609)1.83574133
104Skull defect (HP:0001362)1.82975928
105Chromosomal breakage induced by crosslinking agents (HP:0003221)1.82248582
106Bladder diverticulum (HP:0000015)1.81878091
107Mitral valve prolapse (HP:0001634)1.81863867
108Bowel diverticulosis (HP:0005222)1.81388139
109Abnormality of abdominal situs (HP:0011620)1.81036853
110Abdominal situs inversus (HP:0003363)1.81036853
111Abnormality of the aortic arch (HP:0012303)1.80230858
112Broad phalanx (HP:0006009)1.79139553
113Abnormality of the umbilical cord (HP:0010881)1.77691485
114Overlapping toe (HP:0001845)1.77138649
115Multiple enchondromatosis (HP:0005701)1.76944751
116Absent epiphyses (HP:0010577)1.75623445
117Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.75623445
118Vaginal fistula (HP:0004320)1.75601124
119Glioma (HP:0009733)1.75457103
120Malignant gastrointestinal tract tumors (HP:0006749)1.74366519
121Gastrointestinal carcinoma (HP:0002672)1.74366519
122Insomnia (HP:0100785)1.74282676
123Vertebral compression fractures (HP:0002953)1.74268864
124Asymmetry of the thorax (HP:0001555)1.73566917
125Choanal stenosis (HP:0000452)1.72901353
126Hyperextensible skin (HP:0000974)1.72594432
127Cortical dysplasia (HP:0002539)1.72029786
128Rectal prolapse (HP:0002035)1.70766145
129Duodenal stenosis (HP:0100867)1.70567000
130Small intestinal stenosis (HP:0012848)1.70567000
131Abnormality of reticulocytes (HP:0004312)1.70545224
132Aplasia involving forearm bones (HP:0009822)1.70527025
133Absent forearm bone (HP:0003953)1.70527025
134Congenital glaucoma (HP:0001087)1.70015314
135Broad finger (HP:0001500)1.69912985
136Facial cleft (HP:0002006)1.69905024
137Premature skin wrinkling (HP:0100678)1.69621570
138Rectal fistula (HP:0100590)1.67947420
139Rectovaginal fistula (HP:0000143)1.67947420
140Nonimmune hydrops fetalis (HP:0001790)1.67827062
141Trigonocephaly (HP:0000243)1.66515806
142Optic nerve coloboma (HP:0000588)1.66365845
143Basal cell carcinoma (HP:0002671)1.66275016
144Hypoplasia of the capital femoral epiphysis (HP:0003090)1.65894181
145Supernumerary ribs (HP:0005815)1.65632271
146Abnormality of the duodenum (HP:0002246)1.65409913
147Joint laxity (HP:0001388)1.65264213
148Midface retrusion (HP:0011800)1.65147590
149Megalocornea (HP:0000485)1.64749170
150Aplastic anemia (HP:0001915)1.64172838
151Patellar dislocation (HP:0002999)1.64076991
152Broad toe (HP:0001837)1.63541441
153Flat cornea (HP:0007720)1.63498849
154Abnormality of the Achilles tendon (HP:0005109)1.63317367
155Atrophic scars (HP:0001075)1.61909306
156Wormian bones (HP:0002645)1.61027988
157Transposition of the great arteries (HP:0001669)1.60843238
158Abnormal connection of the cardiac segments (HP:0011545)1.60843238
159Abnormal ventriculo-arterial connection (HP:0011563)1.60843238
160Vertebral arch anomaly (HP:0008438)1.59307035
161Hypoventilation (HP:0002791)1.57496932
162Bowing of the arm (HP:0006488)1.57409267
163Bowed forearm bones (HP:0003956)1.57409267
164Cerebral aneurysm (HP:0004944)1.56598297
165Mitral regurgitation (HP:0001653)1.55679969
166Protruding ear (HP:0000411)1.55145619
167Delayed cranial suture closure (HP:0000270)1.54873127
168Intestinal fistula (HP:0100819)1.54830624
169Breech presentation (HP:0001623)1.54723870
170Spastic diplegia (HP:0001264)1.54681173
171Elbow flexion contracture (HP:0002987)1.54554842
172Natal tooth (HP:0000695)1.52484871

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.28510257
2BUB13.51432462
3WEE13.18866442
4MAP3K103.18355843
5SMG12.96805533
6PKN22.78719055
7PASK2.66981271
8NEK22.56405559
9CDK122.21543298
10VRK22.16674265
11EEF2K2.14692760
12PNCK2.14139759
13TRIB32.02959557
14MKNK12.01608082
15TTK1.99859282
16SRPK11.91114112
17NEK11.83827363
18CDK71.79168042
19SCYL21.76002830
20RPS6KA41.71977573
21PAK41.70887600
22TSSK61.69647396
23BRSK21.64175072
24PLK11.62760024
25ATR1.62453133
26TLK11.62412694
27PTK21.62304919
28TGFBR11.62099018
29IRAK31.57401860
30NTRK11.56116890
31DYRK31.56022454
32RPS6KB21.55482257
33CAMK1G1.51878916
34AURKB1.50736115
35MET1.50665234
36CDK41.50143040
37TESK21.44067577
38TAF11.43966834
39PRKD31.42953350
40MKNK21.41886149
41MAP3K81.41778576
42TYRO31.40438426
43BRSK11.31772416
44EIF2AK11.29645679
45ACVR1B1.27575807
46CHEK21.25094162
47SIK11.24460025
48TESK11.23227182
49PLK31.21232369
50NME21.20219229
51AURKA1.18187717
52CDK61.15914996
53CHEK11.15085415
54EPHB21.15084624
55ILK1.11150445
56FLT31.10305748
57VRK11.10189755
58DDR21.08930365
59STK41.07300523
60LRRK21.07097200
61CAMK1D1.03956857
62PTK61.03666206
63MAP3K91.01091744
64PLK41.00826725
65BRAF1.00548487
66BRD40.99499302
67FGFR40.98337011
68STK100.97001299
69EPHA20.96655696
70PBK0.96393671
71LATS20.95020613
72LATS10.92273104
73ARAF0.91135798
74MTOR0.89771057
75MAP2K30.88196382
76CDK20.87514035
77TTN0.87309045
78ATM0.85851901
79PDGFRA0.82449426
80FGFR10.81793751
81CDK80.81615645
82CDK11A0.81554609
83KDR0.81158518
84ALK0.76209615
85CDK190.75179793
86AKT20.74628976
87EIF2AK30.73103934
88LIMK10.72778022
89CDK150.72296521
90MELK0.72288211
91PAK20.71977398
92PAK10.71443413
93UHMK10.68512519
94FGFR20.68488116
95CDK180.66908419
96CDK10.65609726
97ICK0.63759426
98DMPK0.62146122
99ERBB30.62062102
100ERBB40.61343099
101KSR20.60993106
102IRAK20.60325777
103CDK90.59961421
104MAP3K110.58613379
105CSNK2A20.58018889
106STK30.57812311
107CSNK2A10.57271462
108MOS0.57104700
109CDK140.55755194
110PRPF4B0.54750695
111TAOK20.54611921
112CCNB10.53662571
113DYRK1B0.51427657
114STK38L0.49434130
115ERBB20.49299901
116KSR10.48868769
117CSNK1G30.48451662
118STK160.46473264
119PRKDC0.45957340
120MAP3K30.43104769
121AKT10.42397886
122RPS6KC10.41278976
123RPS6KL10.41278976
124CLK10.41215782
125RPS6KA20.41077061
126MAP2K20.41031266
127CSNK1E0.40454356
128CSNK1A1L0.40220199
129PIM10.40152047
130PDGFRB0.39717457
131BMX0.38413984
132RPS6KA10.37904378
133ZAK0.34648271
134RIPK10.34240344
135PRKCI0.34013656
136RPS6KA50.33834869
137MAPKAPK20.33824461
138DYRK20.32710105
139MAPK140.32338178

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.21076799
2Mismatch repair_Homo sapiens_hsa034304.26758577
3Spliceosome_Homo sapiens_hsa030403.63694893
4Ribosome_Homo sapiens_hsa030103.31457296
5Base excision repair_Homo sapiens_hsa034103.01659291
6RNA transport_Homo sapiens_hsa030132.99751152
7Cell cycle_Homo sapiens_hsa041102.97815185
8One carbon pool by folate_Homo sapiens_hsa006702.75253365
9Nucleotide excision repair_Homo sapiens_hsa034202.63937950
10Homologous recombination_Homo sapiens_hsa034402.58756259
11Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.57078681
12Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.31076401
13mRNA surveillance pathway_Homo sapiens_hsa030152.12697492
14Proteasome_Homo sapiens_hsa030502.11763622
15RNA polymerase_Homo sapiens_hsa030202.10262694
16Pyrimidine metabolism_Homo sapiens_hsa002401.96659811
17Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.90833669
18RNA degradation_Homo sapiens_hsa030181.73072345
19Fanconi anemia pathway_Homo sapiens_hsa034601.72985840
20Basal cell carcinoma_Homo sapiens_hsa052171.59803666
21Vitamin B6 metabolism_Homo sapiens_hsa007501.56485600
22Systemic lupus erythematosus_Homo sapiens_hsa053221.54936223
23Non-homologous end-joining_Homo sapiens_hsa034501.42578030
24p53 signaling pathway_Homo sapiens_hsa041151.41434123
25Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.26295198
26Hippo signaling pathway_Homo sapiens_hsa043901.22061377
27Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.21976515
28Hedgehog signaling pathway_Homo sapiens_hsa043401.20446225
29Basal transcription factors_Homo sapiens_hsa030221.14543047
30Viral carcinogenesis_Homo sapiens_hsa052031.12085330
31HTLV-I infection_Homo sapiens_hsa051661.07781008
32MicroRNAs in cancer_Homo sapiens_hsa052061.07197382
33Prion diseases_Homo sapiens_hsa050201.05907268
34Oocyte meiosis_Homo sapiens_hsa041141.05142829
35Thyroid cancer_Homo sapiens_hsa052161.01860672
36Notch signaling pathway_Homo sapiens_hsa043301.00558745
37Epstein-Barr virus infection_Homo sapiens_hsa051690.98737772
38Bladder cancer_Homo sapiens_hsa052190.97739690
39Biosynthesis of amino acids_Homo sapiens_hsa012300.97063009
40Small cell lung cancer_Homo sapiens_hsa052220.93913218
41Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.93681120
42Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.92771006
43Chronic myeloid leukemia_Homo sapiens_hsa052200.88269347
44Axon guidance_Homo sapiens_hsa043600.88061262
45Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.87914039
46Glioma_Homo sapiens_hsa052140.87283393
47Steroid biosynthesis_Homo sapiens_hsa001000.87214259
48TGF-beta signaling pathway_Homo sapiens_hsa043500.86707029
49Pyruvate metabolism_Homo sapiens_hsa006200.85597666
50Purine metabolism_Homo sapiens_hsa002300.84186258
51Central carbon metabolism in cancer_Homo sapiens_hsa052300.83286686
52Alcoholism_Homo sapiens_hsa050340.82641024
53Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.82564958
54Selenocompound metabolism_Homo sapiens_hsa004500.82443681
55N-Glycan biosynthesis_Homo sapiens_hsa005100.82237354
56Adherens junction_Homo sapiens_hsa045200.79830137
57Vibrio cholerae infection_Homo sapiens_hsa051100.79725013
58Colorectal cancer_Homo sapiens_hsa052100.79015372
59Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.77472763
60Folate biosynthesis_Homo sapiens_hsa007900.77046892
61Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.76649184
62Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.75018701
63Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.72738927
64Transcriptional misregulation in cancer_Homo sapiens_hsa052020.72721972
65Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.71572504
66Fructose and mannose metabolism_Homo sapiens_hsa000510.70029735
67Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.69776969
68Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.68775153
69Herpes simplex infection_Homo sapiens_hsa051680.68520599
70ErbB signaling pathway_Homo sapiens_hsa040120.67928668
71Protein export_Homo sapiens_hsa030600.64693412
72Antigen processing and presentation_Homo sapiens_hsa046120.64613470
73VEGF signaling pathway_Homo sapiens_hsa043700.63296860
74Wnt signaling pathway_Homo sapiens_hsa043100.62759682
75Arginine and proline metabolism_Homo sapiens_hsa003300.62413356
76Proteoglycans in cancer_Homo sapiens_hsa052050.61717059
77Longevity regulating pathway - mammal_Homo sapiens_hsa042110.61669230
78Lysine degradation_Homo sapiens_hsa003100.61605220
79Legionellosis_Homo sapiens_hsa051340.61448867
80Carbon metabolism_Homo sapiens_hsa012000.61209267
81Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.59718622
822-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.58336363
83Pathways in cancer_Homo sapiens_hsa052000.57958858
84Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.57779202
85Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.57744518
86Regulation of actin cytoskeleton_Homo sapiens_hsa048100.57580874
87Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.56314846
88Renal cell carcinoma_Homo sapiens_hsa052110.55055247
89Insulin signaling pathway_Homo sapiens_hsa049100.54487931
90Galactose metabolism_Homo sapiens_hsa000520.53498142
91Gap junction_Homo sapiens_hsa045400.53493381
92Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.53375198
93Viral myocarditis_Homo sapiens_hsa054160.53364555
94Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.52224143
95Sulfur relay system_Homo sapiens_hsa041220.50930288
96Cysteine and methionine metabolism_Homo sapiens_hsa002700.50381894
97Melanoma_Homo sapiens_hsa052180.48121257
98Prostate cancer_Homo sapiens_hsa052150.48024502
99Non-small cell lung cancer_Homo sapiens_hsa052230.47143015
100Endometrial cancer_Homo sapiens_hsa052130.46449247
101Apoptosis_Homo sapiens_hsa042100.46429826
102Pentose phosphate pathway_Homo sapiens_hsa000300.46159372
103HIF-1 signaling pathway_Homo sapiens_hsa040660.46037144
104Tight junction_Homo sapiens_hsa045300.45887504
105Cyanoamino acid metabolism_Homo sapiens_hsa004600.41737639
106Huntingtons disease_Homo sapiens_hsa050160.41039397
107Focal adhesion_Homo sapiens_hsa045100.40345795
108mTOR signaling pathway_Homo sapiens_hsa041500.40313573
109Drug metabolism - other enzymes_Homo sapiens_hsa009830.38900054
110Hepatitis B_Homo sapiens_hsa051610.37602052
111Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.37512632
112Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.35735386
113Glutathione metabolism_Homo sapiens_hsa004800.35007308
114PI3K-Akt signaling pathway_Homo sapiens_hsa041510.34762080
115Maturity onset diabetes of the young_Homo sapiens_hsa049500.34121588
116ECM-receptor interaction_Homo sapiens_hsa045120.33352460
117Neurotrophin signaling pathway_Homo sapiens_hsa047220.30937809
118Thyroid hormone signaling pathway_Homo sapiens_hsa049190.29089703
119Pancreatic cancer_Homo sapiens_hsa052120.26747658
120Shigellosis_Homo sapiens_hsa051310.25532403
121Parkinsons disease_Homo sapiens_hsa050120.24979035
122Melanogenesis_Homo sapiens_hsa049160.22432203
123AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.21226044
124Acute myeloid leukemia_Homo sapiens_hsa052210.20070190
125Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.19851675
126Leukocyte transendothelial migration_Homo sapiens_hsa046700.19469953
127AMPK signaling pathway_Homo sapiens_hsa041520.13892013

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