NTNG2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1modulation by organism of defense response of other organism involved in symbiotic interaction (GO:05.47496530
2positive regulation by organism of defense response of other organism involved in symbiotic interact5.47496530
3modulation by symbiont of host immune response (GO:0052553)5.47496530
4positive regulation by symbiont of host defense response (GO:0052509)5.47496530
5modulation by symbiont of host defense response (GO:0052031)5.47496530
6modulation by organism of immune response of other organism involved in symbiotic interaction (GO:005.47496530
7antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.30643278
8detection of other organism (GO:0098543)4.98829287
9positive regulation of gamma-delta T cell activation (GO:0046645)4.95936823
10leukocyte migration involved in inflammatory response (GO:0002523)4.93340084
11retinal cone cell development (GO:0046549)4.76899893
12detection of bacterium (GO:0016045)4.75144070
13antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.71964662
14synaptic vesicle maturation (GO:0016188)4.58684149
15macrophage activation involved in immune response (GO:0002281)4.58683017
16neutrophil activation involved in immune response (GO:0002283)4.58531097
17antigen processing and presentation of endogenous antigen (GO:0019883)4.46880344
18regulation of rhodopsin mediated signaling pathway (GO:0022400)4.31909354
19microglial cell activation (GO:0001774)4.31349058
20rhodopsin mediated signaling pathway (GO:0016056)4.24133758
21detection of external biotic stimulus (GO:0098581)4.23385697
22negative regulation of lymphocyte mediated immunity (GO:0002707)4.21292053
23regulation of B cell receptor signaling pathway (GO:0050855)4.21279752
24regulation of short-term neuronal synaptic plasticity (GO:0048172)4.20771464
25antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.20033169
26detection of molecule of bacterial origin (GO:0032490)4.15415613
27locomotory exploration behavior (GO:0035641)4.09436234
28neutrophil activation (GO:0042119)4.05714845
29neutrophil mediated immunity (GO:0002446)4.02803352
30negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.98515519
31response to host immune response (GO:0052572)3.98161813
32response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.98161813
33positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.97696193
34response to interleukin-15 (GO:0070672)3.96889911
35positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.95958760
36respiratory burst (GO:0045730)3.95220486
37response to muramyl dipeptide (GO:0032495)3.85453288
38positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.79997973
39layer formation in cerebral cortex (GO:0021819)3.79838233
40negative regulation of cell killing (GO:0031342)3.75349189
41negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.75349189
42positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.73943533
43glomerular visceral epithelial cell development (GO:0072015)3.73775094
44negative regulation of leukocyte mediated immunity (GO:0002704)3.71483510
45detection of biotic stimulus (GO:0009595)3.70038132
46macrophage activation (GO:0042116)3.67102370
47cellular response to interleukin-15 (GO:0071350)3.66523624
48synaptic vesicle docking involved in exocytosis (GO:0016081)3.65539085
49positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.64517509
50sodium ion export (GO:0071436)3.63573866
51regulation of interferon-beta biosynthetic process (GO:0045357)3.61149058
52response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.58318893
53response to host (GO:0075136)3.58318893
54response to host defenses (GO:0052200)3.58318893
55granulocyte activation (GO:0036230)3.57559757
56myeloid leukocyte mediated immunity (GO:0002444)3.51265364
57regulation of gamma-delta T cell activation (GO:0046643)3.50108424
58glomerular epithelial cell development (GO:0072310)3.48582663
59negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.48333142
60synaptic vesicle exocytosis (GO:0016079)3.47988975
61negative regulation of T cell mediated immunity (GO:0002710)3.47359698
62detection of light stimulus involved in sensory perception (GO:0050962)3.47298909
63detection of light stimulus involved in visual perception (GO:0050908)3.47298909
64myeloid cell activation involved in immune response (GO:0002275)3.45922263
65regulation of mast cell degranulation (GO:0043304)3.45213213
66protein localization to synapse (GO:0035418)3.44375368
67regulation of myeloid leukocyte mediated immunity (GO:0002886)3.44299687
68positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.42160244
69negative regulation of erythrocyte differentiation (GO:0045647)3.39150302
70cellular response to type I interferon (GO:0071357)3.38818048
71type I interferon signaling pathway (GO:0060337)3.38818048
72response to type I interferon (GO:0034340)3.36960756
73regulation of synaptic vesicle exocytosis (GO:2000300)3.32852368
74glutamate secretion (GO:0014047)3.31298906
75cellular potassium ion homeostasis (GO:0030007)3.29107831
76activated T cell proliferation (GO:0050798)3.23512530
77photoreceptor cell development (GO:0042461)3.20349215
78defense response to protozoan (GO:0042832)3.19911322
79regulation of leukocyte degranulation (GO:0043300)3.19898539
80positive regulation of guanylate cyclase activity (GO:0031284)3.19675633
81regulation of mast cell activation involved in immune response (GO:0033006)3.19443804
82positive regulation of mast cell activation (GO:0033005)3.19186628
83regulation of ARF protein signal transduction (GO:0032012)3.18494923
84leukocyte aggregation (GO:0070486)3.16830116
85regulation of tumor necrosis factor biosynthetic process (GO:0042534)3.14849512
86leukocyte degranulation (GO:0043299)3.13544245
87photoreceptor cell maintenance (GO:0045494)3.12247712
88B cell receptor signaling pathway (GO:0050853)3.11025311
89eye photoreceptor cell development (GO:0042462)3.09179255
90vocalization behavior (GO:0071625)3.09015862
91regulation of mast cell activation (GO:0033003)3.07142288
92production of molecular mediator involved in inflammatory response (GO:0002532)3.01805141
93regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.01523962
94regulation of T-helper 2 cell differentiation (GO:0045628)2.99785469
95germinal center formation (GO:0002467)2.99107719
96regulation of gamma-delta T cell differentiation (GO:0045586)2.98409101
97immunoglobulin mediated immune response (GO:0016064)2.97460274
98adaptation of signaling pathway (GO:0023058)2.94414435
99exploration behavior (GO:0035640)2.93777258
100negative regulation of phagocytosis (GO:0050765)2.93278185
101negative regulation of interleukin-6 production (GO:0032715)2.90124504
102positive regulation of mast cell degranulation (GO:0043306)2.89913432
103positive regulation of mast cell activation involved in immune response (GO:0033008)2.89913432
104regulation of clathrin-mediated endocytosis (GO:2000369)2.88932281
105regulation of glutamate receptor signaling pathway (GO:1900449)2.87667751
106phototransduction (GO:0007602)2.87475930
107regulation of synaptic vesicle transport (GO:1902803)2.87057777
108regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.86590876
109oxygen transport (GO:0015671)2.84771678
110positive regulation of toll-like receptor signaling pathway (GO:0034123)2.84347083
111regulation of NFAT protein import into nucleus (GO:0051532)2.83265018
112response to pheromone (GO:0019236)2.82843039
113response to protozoan (GO:0001562)2.82778192
114defense response to fungus (GO:0050832)2.81863983
115detection of light stimulus (GO:0009583)2.78313978
116regulation of macrophage cytokine production (GO:0010935)2.76316613
117response to interferon-alpha (GO:0035455)2.76089648
118negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.75942299
119negative regulation of T-helper cell differentiation (GO:0045623)2.75942299
120negative regulation of type 2 immune response (GO:0002829)2.74612022
121regulation of guanylate cyclase activity (GO:0031282)2.74354283
122negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.74263079
123negative regulation of B cell mediated immunity (GO:0002713)2.73636065
124negative regulation of immunoglobulin mediated immune response (GO:0002890)2.73636065
125retinal rod cell development (GO:0046548)2.73605136
126disruption of cells of other organism involved in symbiotic interaction (GO:0051818)2.72714735
127killing of cells in other organism involved in symbiotic interaction (GO:0051883)2.72714735
128response to fungus (GO:0009620)2.72370475
129G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.71614141
130regulation of interleukin-6 biosynthetic process (GO:0045408)2.71491456
131regulation of B cell differentiation (GO:0045577)2.71017325
132positive regulation of Rap GTPase activity (GO:0032854)2.70837454
133regulation of synapse structural plasticity (GO:0051823)2.70438592
134protein-chromophore linkage (GO:0018298)2.67421058
135positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.66849082
136regulation of tolerance induction (GO:0002643)2.66004784
137detection of visible light (GO:0009584)2.65417531
138dendritic spine morphogenesis (GO:0060997)2.64596350
139establishment of nucleus localization (GO:0040023)2.62304406
140positive regulation of synapse maturation (GO:0090129)2.61325290
141phototransduction, visible light (GO:0007603)2.60763053
142regulation of dendritic cell antigen processing and presentation (GO:0002604)2.55512590
143neurotransmitter-gated ion channel clustering (GO:0072578)2.54397971
144proline transport (GO:0015824)2.52707145
145cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.48877374
146cellular extravasation (GO:0045123)2.45338568
147synaptic vesicle endocytosis (GO:0048488)2.43789868
148positive regulation of CREB transcription factor activity (GO:0032793)2.38970207
149cell communication by electrical coupling (GO:0010644)2.38708743
150negative regulation of interleukin-12 production (GO:0032695)2.38487393
151neurotransmitter secretion (GO:0007269)2.37384838
152dendrite morphogenesis (GO:0048813)2.35133365
153response to auditory stimulus (GO:0010996)2.34905843
154pyrimidine nucleobase catabolic process (GO:0006208)2.33579784
155nucleobase catabolic process (GO:0046113)2.32987836
156positive regulation of axon extension (GO:0045773)2.32204167
157positive regulation of membrane potential (GO:0045838)2.31643893
158innervation (GO:0060384)2.31554854
159nerve growth factor signaling pathway (GO:0038180)2.29870924
160regulation of voltage-gated calcium channel activity (GO:1901385)2.29577927
161neutrophil chemotaxis (GO:0030593)2.28224929
162regulation of neuronal synaptic plasticity (GO:0048168)2.27429615
163visual perception (GO:0007601)2.26847605
164regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.26020814
165glomerular basement membrane development (GO:0032836)2.24802028
166sensory perception of light stimulus (GO:0050953)2.24040235
167epithelial cell differentiation involved in kidney development (GO:0035850)2.23816482
168regulation of axon guidance (GO:1902667)2.23693666
169clathrin coat assembly (GO:0048268)2.23691329
170neuron recognition (GO:0008038)2.22269049
171response to peptidoglycan (GO:0032494)2.22209348
172neutrophil migration (GO:1990266)2.22085508
173axonal fasciculation (GO:0007413)2.21837032
174regulation of ARF GTPase activity (GO:0032312)2.21771887
175activation of protein kinase A activity (GO:0034199)2.21498460
176axon extension (GO:0048675)2.18449117
177establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.14115748
178mitochondrion transport along microtubule (GO:0047497)2.14115748
179cytoskeletal anchoring at plasma membrane (GO:0007016)2.13645780
180granulocyte migration (GO:0097530)2.13225489
181regulation of regulated secretory pathway (GO:1903305)2.12952740
182potassium ion import (GO:0010107)2.12567670
183long-term memory (GO:0007616)2.11452865
184ionotropic glutamate receptor signaling pathway (GO:0035235)2.11440021
185positive regulation of neurotransmitter transport (GO:0051590)2.10407698
186neuromuscular process controlling balance (GO:0050885)2.10276063
187synaptic transmission, glutamatergic (GO:0035249)2.09773430
188positive regulation of histone deacetylation (GO:0031065)2.09510941
189regulation of neurotransmitter secretion (GO:0046928)2.09420351
190regulation of long-term neuronal synaptic plasticity (GO:0048169)2.07532603

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human4.32319564
2EZH2_22144423_ChIP-Seq_EOC_Human2.87540812
3STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.52410563
4DROSHA_22980978_ChIP-Seq_HELA_Human2.38981138
5SCL_19346495_ChIP-Seq_HPC-7_Human2.33108332
6RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.30258949
7FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.22947910
8VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.19198455
9BP1_19119308_ChIP-ChIP_Hs578T_Human2.18623890
10EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.13340623
11MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.10350303
12* KDM2B_26808549_Chip-Seq_SUP-B15_Human2.07523745
13SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.00098382
14IKZF1_21737484_ChIP-ChIP_HCT116_Human1.96790062
15MYB_21317192_ChIP-Seq_ERMYB_Mouse1.96194165
16* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.93289620
17* SPI1_23547873_ChIP-Seq_NB4_Human1.90803299
18* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.90580757
19SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.87740092
20SUZ12_27294783_Chip-Seq_ESCs_Mouse1.86473829
21* KDM2B_26808549_Chip-Seq_K562_Human1.85934897
22RNF2_18974828_ChIP-Seq_MESCs_Mouse1.85901193
23EZH2_18974828_ChIP-Seq_MESCs_Mouse1.85901193
24NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.85275866
25* JARID2_20064375_ChIP-Seq_MESCs_Mouse1.84151712
26* RUNX1_22412390_ChIP-Seq_EML_Mouse1.81759035
27UTX_26944678_Chip-Seq_JUKART_Human1.77235249
28* EZH2_27294783_Chip-Seq_ESCs_Mouse1.75492001
29IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.73613044
30SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.73598021
31THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.73513828
32* JARID2_20075857_ChIP-Seq_MESCs_Mouse1.72977380
33KDM2B_26808549_Chip-Seq_DND41_Human1.72035714
34RNF2_27304074_Chip-Seq_ESCs_Mouse1.69936976
35SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.69007540
36* RARB_27405468_Chip-Seq_BRAIN_Mouse1.67514276
37LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.63122286
38GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.60977724
39MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.60744597
40REST_21632747_ChIP-Seq_MESCs_Mouse1.60142447
41MYB_26560356_Chip-Seq_TH2_Human1.58242219
42LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.58169674
43RUNX_20019798_ChIP-Seq_JUKART_Human1.53609858
44GBX2_23144817_ChIP-Seq_PC3_Human1.53566120
45SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.49857404
46MAF_26560356_Chip-Seq_TH2_Human1.48394117
47KDM2B_26808549_Chip-Seq_JURKAT_Human1.46917386
48TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.46810408
49* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.46035437
50EZH2_27304074_Chip-Seq_ESCs_Mouse1.42028420
51LXR_22292898_ChIP-Seq_THP-1_Human1.41436866
52SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.39822727
53SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.38239790
54REST_18959480_ChIP-ChIP_MESCs_Mouse1.37910118
55TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.35922741
56WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.35144041
57GATA3_27048872_Chip-Seq_THYMUS_Human1.34465281
58WT1_25993318_ChIP-Seq_PODOCYTE_Human1.32979508
59GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.32686380
60STAT6_21828071_ChIP-Seq_BEAS2B_Human1.32179967
61SPI1_23127762_ChIP-Seq_K562_Human1.31254950
62* TCF7_22412390_ChIP-Seq_EML_Mouse1.30728601
63STAT4_19710469_ChIP-ChIP_TH1__Mouse1.30548148
64* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.29222132
65MYB_26560356_Chip-Seq_TH1_Human1.29021834
66KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.27169153
67VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.27036493
68ZFP281_18757296_ChIP-ChIP_E14_Mouse1.26552333
69CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.26355701
70KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.26261076
71SMAD_19615063_ChIP-ChIP_OVARY_Human1.25305114
72DNAJC2_21179169_ChIP-ChIP_NT2_Human1.24804290
73NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.22770615
74CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.20829519
75AR_21572438_ChIP-Seq_LNCaP_Human1.19317038
76EGR1_19374776_ChIP-ChIP_THP-1_Human1.16980602
77VDR_24787735_ChIP-Seq_THP-1_Human1.16844916
78EED_16625203_ChIP-ChIP_MESCs_Mouse1.15882279
79ERG_21242973_ChIP-ChIP_JURKAT_Human1.12995827
80PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.12489057
81SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.12388202
82* MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.11801184
83* BCL6_27268052_Chip-Seq_Bcells_Human1.11418339
84STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.11237822
85MYC_22102868_ChIP-Seq_BL_Human1.09990302
86IRF8_27001747_Chip-Seq_BMDM_Mouse1.09970447
87DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.08936856
88P53_22127205_ChIP-Seq_FIBROBLAST_Human1.08304162
89SMAD3_21741376_ChIP-Seq_HESCs_Human1.08206037
90PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.07260946
91ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.06193831
92PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.06161809
93* OCT4_19829295_ChIP-Seq_ESCs_Human1.05098691
94ZNF217_24962896_ChIP-Seq_MCF-7_Human1.04795014
95CDX2_19796622_ChIP-Seq_MESCs_Mouse1.04604538
96ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.04551831
97RING1B_27294783_Chip-Seq_ESCs_Mouse1.04459007
98NR3C1_23031785_ChIP-Seq_PC12_Mouse1.04247522
99AHR_22903824_ChIP-Seq_MCF-7_Human1.04163692
100CTCF_27219007_Chip-Seq_ERYTHROID_Human1.04016377
101GATA1_19941827_ChIP-Seq_MEL_Mouse1.03538868
102CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.03188769
103IRF8_21731497_ChIP-ChIP_J774_Mouse1.02962780
104PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.02957112
105* BCOR_27268052_Chip-Seq_Bcells_Human1.02518840
106ZFP281_27345836_Chip-Seq_ESCs_Mouse1.02014237
107CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.00456431
108RING1B_27294783_Chip-Seq_NPCs_Mouse1.00010432
109SA1_27219007_Chip-Seq_ERYTHROID_Human0.99796515
110PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.99124846
111VDR_21846776_ChIP-Seq_THP-1_Human0.98085015
112* SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.97902363
113EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.97880454
114EGR1_19032775_ChIP-ChIP_M12_Human0.97435039
115PU.1_20513432_ChIP-Seq_Bcells_Mouse0.97256313
116TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.96993502
117SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.96465099
118BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.95798326
119Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.95603828
120P68_20966046_ChIP-Seq_HELA_Human0.95553945
121* AR_19668381_ChIP-Seq_PC3_Human0.95358598
122SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.94666483
123ARNT_22903824_ChIP-Seq_MCF-7_Human0.94253964
124E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.93903431
125IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.92724916
126GATA1_22025678_ChIP-Seq_K562_Human0.92589880
127STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.92573952
128* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.92003474
129FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.91651700
130ELK3_25401928_ChIP-Seq_HUVEC_Human0.91350841
131GATA2_22383799_ChIP-Seq_G1ME_Mouse0.91276046
132GATA3_26560356_Chip-Seq_TH2_Human0.91267770
133CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.91150530
134GATA1_22383799_ChIP-Seq_G1ME_Mouse0.90043511
135* GATA2_21666600_ChIP-Seq_HMVEC_Human0.89853014
136SMAD4_21741376_ChIP-Seq_HESCs_Human0.88693353
137ESR2_21235772_ChIP-Seq_MCF-7_Human0.87465807
138* SMC4_20622854_ChIP-Seq_HELA_Human0.87284372
139PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.87188889
140NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.87007145
141SOX2_21211035_ChIP-Seq_LN229_Gbm0.86554453
142GATA2_19941826_ChIP-Seq_K562_Human0.86523129
143NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.86378423
144GATA1_19941826_ChIP-Seq_K562_Human0.86290172
145MAF_26560356_Chip-Seq_TH1_Human0.85989076
146VDR_24763502_ChIP-Seq_THP-1_Human0.85237340

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.00224647
2MP0005551_abnormal_eye_electrophysiolog4.25654079
3MP0003303_peritoneal_inflammation3.65221325
4MP0003011_delayed_dark_adaptation3.42731928
5MP0005253_abnormal_eye_physiology2.91759553
6MP0006072_abnormal_retinal_apoptosis2.89838843
7MP0003635_abnormal_synaptic_transmissio2.54223274
8MP0004510_myositis2.46171920
9MP0005423_abnormal_somatic_nervous2.39731017
10MP0004270_analgesia2.25843266
11MP0006082_CNS_inflammation2.17230696
12MP0004858_abnormal_nervous_system2.15412220
13MP0000569_abnormal_digit_pigmentation2.12653498
14MP0002063_abnormal_learning/memory/cond2.08517305
15MP0002090_abnormal_vision1.96766615
16MP0002735_abnormal_chemical_nociception1.94480498
17MP0008260_abnormal_autophagy1.92043777
18MP0003436_decreased_susceptibility_to1.91742537
19MP0003690_abnormal_glial_cell1.91178666
20MP0008961_abnormal_basal_metabolism1.85343726
21MP0005195_abnormal_posterior_eye1.84367620
22MP0002396_abnormal_hematopoietic_system1.83963734
23MP0009278_abnormal_bone_marrow1.79511220
24MP0003191_abnormal_cellular_cholesterol1.79060020
25MP0009780_abnormal_chondrocyte_physiolo1.75115698
26MP0002132_abnormal_respiratory_system1.70664640
27MP0003183_abnormal_peptide_metabolism1.67072419
28MP0003075_altered_response_to1.65643023
29MP0002398_abnormal_bone_marrow1.65356798
30MP0005076_abnormal_cell_differentiation1.63487889
31MP0000716_abnormal_immune_system1.62578070
32MP0003172_abnormal_lysosome_physiology1.62457705
33MP0001348_abnormal_lacrimal_gland1.60744979
34MP0002277_abnormal_respiratory_mucosa1.59849814
35MP0002064_seizures1.59795513
36MP0003763_abnormal_thymus_physiology1.59736225
37MP0001968_abnormal_touch/_nociception1.59087088
38MP0009745_abnormal_behavioral_response1.57457796
39MP0003866_abnormal_defecation1.54112097
40MP0003828_pulmonary_edema1.51607364
41MP0003879_abnormal_hair_cell1.51096015
42MP0001986_abnormal_taste_sensitivity1.49684901
43MP0009764_decreased_sensitivity_to1.43350933
44MP0001790_abnormal_immune_system1.43246007
45MP0005387_immune_system_phenotype1.43246007
46MP0002734_abnormal_mechanical_nocicepti1.42375709
47* MP0001486_abnormal_startle_reflex1.41002958
48MP0001502_abnormal_circadian_rhythm1.39641754
49MP0002229_neurodegeneration1.39528726
50MP0009046_muscle_twitch1.38348663
51MP0004885_abnormal_endolymph1.37278526
52MP0000465_gastrointestinal_hemorrhage1.36343407
53MP0003329_amyloid_beta_deposits1.35259430
54MP0009785_altered_susceptibility_to1.35126353
55MP0002419_abnormal_innate_immunity1.34405930
56MP0003787_abnormal_imprinting1.32297922
57MP0004811_abnormal_neuron_physiology1.30910280
58MP0002572_abnormal_emotion/affect_behav1.30585631
59MP0001501_abnormal_sleep_pattern1.30055171
60MP0002882_abnormal_neuron_morphology1.29988655
61MP0000778_abnormal_nervous_system1.29810776
62MP0008569_lethality_at_weaning1.28381059
63MP0001324_abnormal_eye_pigmentation1.27744931
64MP0003880_abnormal_central_pattern1.26247114
65MP0005397_hematopoietic_system_phenotyp1.26097626
66MP0001545_abnormal_hematopoietic_system1.26097626
67MP0005000_abnormal_immune_tolerance1.24240048
68MP0010155_abnormal_intestine_physiology1.23943966
69MP0000685_abnormal_immune_system1.22412852
70MP0004947_skin_inflammation1.21486901
71MP0002736_abnormal_nociception_after1.21275023
72MP0002429_abnormal_blood_cell1.20534025
73MP0002722_abnormal_immune_system1.20133865
74MP0005391_vision/eye_phenotype1.18894822
75MP0001851_eye_inflammation1.17647283
76MP0000689_abnormal_spleen_morphology1.17491700
77MP0005310_abnormal_salivary_gland1.17227213
78MP0003300_gastrointestinal_ulcer1.15603305
79MP0001440_abnormal_grooming_behavior1.14406843
80MP0001533_abnormal_skeleton_physiology1.13342922
81MP0000703_abnormal_thymus_morphology1.13300180
82MP0002653_abnormal_ependyma_morphology1.12890745
83MP0001970_abnormal_pain_threshold1.12346453
84MP0004381_abnormal_hair_follicle1.11058290
85MP0002733_abnormal_thermal_nociception1.11023319
86MP0008469_abnormal_protein_level1.09178423
87MP0002909_abnormal_adrenal_gland1.07833375
88MP0004883_abnormal_blood_vessel1.07739641
89MP0001835_abnormal_antigen_presentation1.06800237
90MP0004130_abnormal_muscle_cell1.06705616
91MP0001800_abnormal_humoral_immune1.05505950
92MP0005025_abnormal_response_to1.05488702
93MP0003045_fibrosis1.04796418
94MP0002184_abnormal_innervation1.02095571
95MP0002452_abnormal_antigen_presenting1.01082543
96MP0002752_abnormal_somatic_nervous1.00572467
97MP0002928_abnormal_bile_duct1.00168887
98MP0000604_amyloidosis0.97359418
99MP0003634_abnormal_glial_cell0.96706990
100MP0005623_abnormal_meninges_morphology0.96506172
101MP0001819_abnormal_immune_cell0.96181199
102MP0002420_abnormal_adaptive_immunity0.95850542
103MP0002723_abnormal_immune_serum0.95773263
104MP0005671_abnormal_response_to0.95770960
105MP0002067_abnormal_sensory_capabilities0.95294494
106MP0000920_abnormal_myelination0.92371977
107MP0000015_abnormal_ear_pigmentation0.91270806
108MP0002148_abnormal_hypersensitivity_rea0.90762892
109MP0005390_skeleton_phenotype0.88658848
110MP0004233_abnormal_muscle_weight0.88596017
111MP0000955_abnormal_spinal_cord0.86363437
112MP0002272_abnormal_nervous_system0.85077967
113MP0005464_abnormal_platelet_physiology0.84673166
114MP0005166_decreased_susceptibility_to0.83061735
115MP0003091_abnormal_cell_migration0.82553128
116MP0004742_abnormal_vestibular_system0.81918906
117MP0005075_abnormal_melanosome_morpholog0.81545586
118MP0003633_abnormal_nervous_system0.80605281
119MP0005377_hearing/vestibular/ear_phenot0.79602918
120MP0003878_abnormal_ear_physiology0.79602918
121MP0002089_abnormal_postnatal_growth/wei0.78498676
122MP0005164_abnormal_response_to0.77367376
123MP0002405_respiratory_system_inflammati0.73720110
124MP0010352_gastrointestinal_tract_polyps0.73508203
125MP0009765_abnormal_xenobiotic_induced0.72016226
126MP0005167_abnormal_blood-brain_barrier0.72013231
127MP0001845_abnormal_inflammatory_respons0.71748255
128MP0004924_abnormal_behavior0.71098274
129MP0005386_behavior/neurological_phenoty0.71098274
130MP0005535_abnormal_body_temperature0.70537430
131MP0002066_abnormal_motor_capabilities/c0.70452903
132MP0001485_abnormal_pinna_reflex0.69662662
133MP0005083_abnormal_biliary_tract0.69385105
134MP0002998_abnormal_bone_remodeling0.67632210
135MP0002133_abnormal_respiratory_system0.67363538
136MP0002557_abnormal_social/conspecific_i0.65237836
137MP0002638_abnormal_pupillary_reflex0.64288143
138MP0005187_abnormal_penis_morphology0.63951815
139MP0008874_decreased_physiological_sensi0.63406858
140MP0003724_increased_susceptibility_to0.63269912

Predicted human phenotypes

RankGene SetZ-score
1Congenital stationary night blindness (HP:0007642)7.17569124
2Bony spicule pigmentary retinopathy (HP:0007737)5.79151738
3Central scotoma (HP:0000603)5.70885563
4Hypochromic microcytic anemia (HP:0004840)5.66063994
5Dyschromatopsia (HP:0007641)5.42508506
6Abnormality of macular pigmentation (HP:0008002)4.74612719
7Absent rod-and cone-mediated responses on ERG (HP:0007688)4.70512576
8Pigmentary retinal degeneration (HP:0001146)4.62626013
9Abnormal rod and cone electroretinograms (HP:0008323)4.55766184
10Scotoma (HP:0000575)4.44288195
11Gastrointestinal infarctions (HP:0005244)3.98590955
12Hypochromic anemia (HP:0001931)3.97432258
13Recurrent skin infections (HP:0001581)3.94693681
14Chronic mucocutaneous candidiasis (HP:0002728)3.91910081
15Recurrent cutaneous fungal infections (HP:0011370)3.91910081
16Meningitis (HP:0001287)3.86257944
17Abnormal delayed hypersensitivity skin test (HP:0002963)3.61857388
18Keratoconjunctivitis sicca (HP:0001097)3.59599967
19Pendular nystagmus (HP:0012043)3.55612672
20Episodic fever (HP:0001954)3.46007722
21Chorioretinal atrophy (HP:0000533)3.43544181
22Increased IgE level (HP:0003212)3.38145332
23Encephalitis (HP:0002383)3.34657943
24Keratoconjunctivitis (HP:0001096)3.34014091
25Eczematoid dermatitis (HP:0000976)3.32085757
26Prolonged bleeding time (HP:0003010)3.29584939
27Abolished electroretinogram (ERG) (HP:0000550)3.22349655
28Spontaneous hematomas (HP:0007420)3.18521637
29Peritonitis (HP:0002586)3.15752760
30Posterior subcapsular cataract (HP:0007787)3.14897561
31Photophobia (HP:0000613)3.14461222
32Hemoptysis (HP:0002105)3.14322322
33Supranuclear gaze palsy (HP:0000605)3.13694928
34Urticaria (HP:0001025)3.12526422
35Attenuation of retinal blood vessels (HP:0007843)3.07378106
36Decreased central vision (HP:0007663)3.06319904
37Recurrent abscess formation (HP:0002722)3.05899822
38Choroideremia (HP:0001139)3.03150229
39Chest pain (HP:0100749)3.00030819
40Myokymia (HP:0002411)2.97613327
41Abnormality of the heme biosynthetic pathway (HP:0010472)2.97166891
42Macular degeneration (HP:0000608)2.91705587
43Interstitial pulmonary disease (HP:0006530)2.87108131
44Type II diabetes mellitus (HP:0005978)2.82948530
45Visual hallucinations (HP:0002367)2.75754609
46Microcytic anemia (HP:0001935)2.75687119
47Mutism (HP:0002300)2.64569308
48Recurrent bacterial skin infections (HP:0005406)2.62731648
49Recurrent gram-negative bacterial infections (HP:0005420)2.61449700
50Severe visual impairment (HP:0001141)2.60028022
51Constricted visual fields (HP:0001133)2.59599662
52Leukocytosis (HP:0001974)2.59370100
53Epileptic encephalopathy (HP:0200134)2.55854475
54Amyloidosis (HP:0011034)2.55255022
55Retrobulbar optic neuritis (HP:0100654)2.54861610
56Optic neuritis (HP:0100653)2.54861610
57Pulmonary embolism (HP:0002204)2.54842704
58Increased corneal curvature (HP:0100692)2.45097039
59Keratoconus (HP:0000563)2.45097039
60Cone-rod dystrophy (HP:0000548)2.43704086
61Anorexia (HP:0002039)2.41937761
62Focal seizures (HP:0007359)2.38557529
63Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.38368331
64Mediastinal lymphadenopathy (HP:0100721)2.37430362
65Epistaxis (HP:0000421)2.36462772
66Gingival bleeding (HP:0000225)2.35856068
67Progressive visual loss (HP:0000529)2.33986277
68Orchitis (HP:0100796)2.33695000
69Papilledema (HP:0001085)2.32881251
70Sepsis (HP:0100806)2.32688776
71Abnormality of the endocardium (HP:0004306)2.32161679
72Focal motor seizures (HP:0011153)2.30613864
73Stomatitis (HP:0010280)2.30106879
74Slow saccadic eye movements (HP:0000514)2.25577616
75Panhypogammaglobulinemia (HP:0003139)2.25108769
76Myositis (HP:0100614)2.24888095
77Autoimmune thrombocytopenia (HP:0001973)2.24772002
78Abnormality of the pleura (HP:0002103)2.22008192
79Vertigo (HP:0002321)2.21950854
80Vitreoretinal degeneration (HP:0000655)2.21647479
81Osteomyelitis (HP:0002754)2.17663162
82Cheilitis (HP:0100825)2.17519044
83Febrile seizures (HP:0002373)2.13137054
84Genetic anticipation (HP:0003743)2.12982205
85Abnormality of the peritoneum (HP:0002585)2.12159739
86Granulocytopenia (HP:0001913)2.12025704
87Subcapsular cataract (HP:0000523)2.10286042
88Petechiae (HP:0000967)2.07555547
89Inflammation of the large intestine (HP:0002037)2.07058979
90Abnormality of macrophages (HP:0004311)2.06253585
91Difficulty running (HP:0009046)2.05896935
92Toxemia of pregnancy (HP:0100603)2.04787368
93Recurrent viral infections (HP:0004429)2.04408486
94Aqueductal stenosis (HP:0002410)2.04110710
95Urinary bladder sphincter dysfunction (HP:0002839)2.03051901
96Abnormal hemoglobin (HP:0011902)2.02467502
97Ankle clonus (HP:0011448)2.00961041
98Progressive cerebellar ataxia (HP:0002073)2.00821636
99Acne (HP:0001061)1.99581866
100Gastrointestinal inflammation (HP:0004386)1.98781038
101Elevated erythrocyte sedimentation rate (HP:0003565)1.98241004
102Abnormality of the pericardium (HP:0001697)1.97031494
103Gangrene (HP:0100758)1.94539926
104Gingivitis (HP:0000230)1.93800729
105Action tremor (HP:0002345)1.91584117
106Polycythemia (HP:0001901)1.91299044
107Diplopia (HP:0000651)1.91216120
108Abnormality of binocular vision (HP:0011514)1.91216120
109Chronic otitis media (HP:0000389)1.90399272
110Obstructive lung disease (HP:0006536)1.89946126
111Chronic obstructive pulmonary disease (HP:0006510)1.89946126
112Hyperacusis (HP:0010780)1.89656539
113Inappropriate behavior (HP:0000719)1.87411243
114Hypergammaglobulinemia (HP:0010702)1.86911045
115Neuronal loss in central nervous system (HP:0002529)1.84539469
116Macroorchidism (HP:0000053)1.84506219
117Increased IgM level (HP:0003496)1.84427219
118Recurrent fungal infections (HP:0002841)1.84105967
119Apathy (HP:0000741)1.83355134
120Cellulitis (HP:0100658)1.82443611
121T lymphocytopenia (HP:0005403)1.82068401
122Truncal ataxia (HP:0002078)1.81945813
123Poor eye contact (HP:0000817)1.81431993
124Metaphyseal cupping (HP:0003021)1.80836527
125Glomerulopathy (HP:0100820)1.80677171
126Impaired social interactions (HP:0000735)1.80138912
127Abnormal social behavior (HP:0012433)1.80138912
128Abnormality of T cell number (HP:0011839)1.79538566
129Anomalous pulmonary venous return (HP:0010772)1.79309169
130Abnormality of T cells (HP:0002843)1.78899750
131Rapidly progressive (HP:0003678)1.78863444
132Obstructive sleep apnea (HP:0002870)1.77434822
133Depression (HP:0000716)1.76858895
134Hemiplegia (HP:0002301)1.76805152
135Absence seizures (HP:0002121)1.76119555
136Annular pancreas (HP:0001734)1.75811601
137Skin rash (HP:0000988)1.75606133
138Pustule (HP:0200039)1.75588933
139Nasal polyposis (HP:0100582)1.74703136
140Postural instability (HP:0002172)1.73606139
141Skin ulcer (HP:0200042)1.72967773
142Eosinophilia (HP:0001880)1.71957486
143Neurofibrillary tangles (HP:0002185)1.71742709
144Mesangial abnormality (HP:0001966)1.71369178
145Retinitis pigmentosa (HP:0000510)1.70876891
146Hematochezia (HP:0002573)1.70471126
147Hypermelanotic macule (HP:0001034)1.68834895
148Nephritis (HP:0000123)1.68434651
149Generalized tonic-clonic seizures (HP:0002069)1.67155001
150Arterial thrombosis (HP:0004420)1.65292614
151Retinal atrophy (HP:0001105)1.65086406
152Diminished motivation (HP:0000745)1.65018502
153Dysdiadochokinesis (HP:0002075)1.64706334
154Abnormality of the lower motor neuron (HP:0002366)1.62640353
155Urinary urgency (HP:0000012)1.61944777
156Insomnia (HP:0100785)1.60904543
157Amyotrophic lateral sclerosis (HP:0007354)1.60319329
158Vasculitis (HP:0002633)1.60216012
159Cerebral inclusion bodies (HP:0100314)1.59315922
160Glomerulonephritis (HP:0000099)1.58472114
161Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.58284471
162Enlarged penis (HP:0000040)1.56962871
163Decreased electroretinogram (ERG) amplitude (HP:0000654)1.56719307
164Stereotypic behavior (HP:0000733)1.56600186
165Broad-based gait (HP:0002136)1.55900408
166Pulmonary infiltrates (HP:0002113)1.55333459
167Elfin facies (HP:0004428)1.54600891

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK13.78853854
2MAP3K93.21449144
3TNK22.98688416
4MAP2K32.98045397
5SIK22.58921909
6PAK62.31162835
7KSR22.15815020
8MAP3K112.09121094
9NTRK31.83368767
10FES1.81973789
11ZAP701.81676329
12NTRK21.77181786
13MINK11.76358429
14DAPK21.75922091
15CAMKK11.73569871
16KSR11.67732577
17CAMK1G1.60697246
18TRIB31.59252067
19BTK1.55492340
20ALK1.53919199
21GRK11.52099572
22MAP3K131.47696890
23RIPK41.47026974
24PHKG11.45679675
25PHKG21.45679675
26MAP4K11.45318817
27MAP3K141.45193621
28TBK11.44822124
29EPHB11.42332910
30PRKCH1.39390723
31PRKD31.33061898
32SIK31.32709621
33TAOK11.29698000
34JAK11.28805139
35MAP3K31.24711589
36MAP3K41.23854138
37RIPK11.23426203
38CAMK1D1.22272513
39NTRK11.22186310
40MAP3K71.19621380
41KIT1.18810808
42ERN11.18102250
43EPHB21.16880115
44MAP3K101.16480402
45PRKD21.12827089
46PKN21.12328127
47RET1.11090822
48JAK31.07923444
49LYN1.07878672
50FGFR31.07087194
51IRAK41.06821364
52CDK51.06429896
53CDK191.03690767
54MAPK121.00087171
55STK110.98416119
56TAOK30.96922216
57HCK0.93893361
58EPHA40.92827612
59TAOK20.92359809
60LCK0.91231184
61TYK20.90454503
62STK380.89317701
63BMX0.87739884
64BLK0.87250788
65RPS6KA20.85230260
66MAP2K40.83989881
67SGK20.82708409
68PRPF4B0.81831565
69PRKCZ0.81752981
70MARK20.81045082
71MARK30.80095984
72YES10.80055519
73IRAK10.79853842
74PAK30.79729250
75PKN10.79319554
76PTK2B0.79103855
77ITK0.78501973
78FYN0.76823781
79UHMK10.75516102
80BMPR20.74438800
81SYK0.74026623
82TEC0.73221679
83IKBKE0.73215875
84MAPK130.71462796
85SGK30.71105383
86CLK10.70270377
87MAP3K10.69901458
88PDK10.69022110
89SGK2230.69018942
90SGK4940.69018942
91JAK20.67216593
92CSK0.65178540
93HIPK20.64650193
94LATS20.63206361
95FGR0.62702898
96SIK10.61602345
97DAPK10.60952621
98CAMKK20.60256482
99WNK10.58611728
100PTK60.57135941
101CHUK0.56873835
102LRRK20.56739205
103SGK10.56728340
104FGFR40.56318259
105MAP2K70.55979582
106CAMK10.55727514
107MAPK70.54960380
108PDPK10.54616025
109IRAK20.54205125
110EPHA30.54007924
111TXK0.53621949
112CSF1R0.53400381
113MAP2K60.53177927
114EEF2K0.52775278
115LMTK20.52133417
116GRK60.51026900
117CAMK40.50714138
118DYRK1B0.50132323
119TTN0.49885097
120DMPK0.49863915
121MAP3K50.49657071
122IKBKB0.49160904
123TYRO30.48731479
124PRKCQ0.47566484
125ICK0.47460220
126ERBB20.47100335
127RAF10.46576676
128ERBB30.46225240
129PRKAA10.45498820
130DYRK1A0.45089172
131MAP3K120.43360655
132CDK180.42952053
133MATK0.42895669
134MAP3K60.42854812
135CDK150.41912889
136MAP3K20.41262791
137GRK50.40592973

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047445.11221428
2Synaptic vesicle cycle_Homo sapiens_hsa047211.91089037
3Olfactory transduction_Homo sapiens_hsa047401.88611928
4Leishmaniasis_Homo sapiens_hsa051401.54982952
5Morphine addiction_Homo sapiens_hsa050321.47039464
6Circadian entrainment_Homo sapiens_hsa047131.45581302
7GABAergic synapse_Homo sapiens_hsa047271.39753566
8Asthma_Homo sapiens_hsa053101.39466903
9Measles_Homo sapiens_hsa051621.38373015
10Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.35404583
11Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.33866657
12Cholinergic synapse_Homo sapiens_hsa047251.33146633
13Osteoclast differentiation_Homo sapiens_hsa043801.32563775
14Type II diabetes mellitus_Homo sapiens_hsa049301.27437054
15Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.26768173
16Primary immunodeficiency_Homo sapiens_hsa053401.25075267
17Glutamatergic synapse_Homo sapiens_hsa047241.24237392
18Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.21767375
19Long-term potentiation_Homo sapiens_hsa047201.21131553
20Chemokine signaling pathway_Homo sapiens_hsa040621.21127550
21Neurotrophin signaling pathway_Homo sapiens_hsa047221.19715837
22Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.19202021
23Nicotine addiction_Homo sapiens_hsa050331.17845414
24Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.16772702
25Salivary secretion_Homo sapiens_hsa049701.16611334
26Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.15480192
27Aldosterone synthesis and secretion_Homo sapiens_hsa049251.15142117
28RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.14740630
29Dopaminergic synapse_Homo sapiens_hsa047281.13458434
30Phagosome_Homo sapiens_hsa041451.13376772
31Influenza A_Homo sapiens_hsa051641.12967672
32VEGF signaling pathway_Homo sapiens_hsa043701.11369726
33Dorso-ventral axis formation_Homo sapiens_hsa043201.10334105
34B cell receptor signaling pathway_Homo sapiens_hsa046621.10313979
35Oxytocin signaling pathway_Homo sapiens_hsa049211.09721559
36Glioma_Homo sapiens_hsa052141.07932109
37Staphylococcus aureus infection_Homo sapiens_hsa051501.07539356
38Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.06470612
39Gastric acid secretion_Homo sapiens_hsa049711.04488984
40mTOR signaling pathway_Homo sapiens_hsa041501.03625067
41Legionellosis_Homo sapiens_hsa051341.03057028
42Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.02759882
43Jak-STAT signaling pathway_Homo sapiens_hsa046301.02229666
44Hematopoietic cell lineage_Homo sapiens_hsa046401.01681269
45Autoimmune thyroid disease_Homo sapiens_hsa053201.00621843
46Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.99324577
47Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.99029934
48* Axon guidance_Homo sapiens_hsa043600.98800375
49Toll-like receptor signaling pathway_Homo sapiens_hsa046200.97076308
50TNF signaling pathway_Homo sapiens_hsa046680.96592475
51Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.95805150
52Tuberculosis_Homo sapiens_hsa051520.95047517
53Insulin secretion_Homo sapiens_hsa049110.93998842
54Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.93640072
55Renin secretion_Homo sapiens_hsa049240.93182736
56Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.92359114
57Hepatitis C_Homo sapiens_hsa051600.91478301
58Phosphatidylinositol signaling system_Homo sapiens_hsa040700.90686911
59AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.89878616
60ErbB signaling pathway_Homo sapiens_hsa040120.88552676
61GnRH signaling pathway_Homo sapiens_hsa049120.88289897
62cAMP signaling pathway_Homo sapiens_hsa040240.86609007
63Hepatitis B_Homo sapiens_hsa051610.86569032
64Pertussis_Homo sapiens_hsa051330.85046270
65cGMP-PKG signaling pathway_Homo sapiens_hsa040220.83941953
66MAPK signaling pathway_Homo sapiens_hsa040100.83473415
67Inositol phosphate metabolism_Homo sapiens_hsa005620.82385792
68Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.82311921
69T cell receptor signaling pathway_Homo sapiens_hsa046600.82044879
70Estrogen signaling pathway_Homo sapiens_hsa049150.81760369
71Phospholipase D signaling pathway_Homo sapiens_hsa040720.81696013
72Chronic myeloid leukemia_Homo sapiens_hsa052200.81392499
73Endometrial cancer_Homo sapiens_hsa052130.80361850
74Toxoplasmosis_Homo sapiens_hsa051450.80259920
75Non-small cell lung cancer_Homo sapiens_hsa052230.79812451
76Renal cell carcinoma_Homo sapiens_hsa052110.79798710
77Nitrogen metabolism_Homo sapiens_hsa009100.79584258
78NOD-like receptor signaling pathway_Homo sapiens_hsa046210.79237379
79Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.78173057
80Serotonergic synapse_Homo sapiens_hsa047260.78071088
81Pancreatic cancer_Homo sapiens_hsa052120.77975693
82Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.77084611
83Dilated cardiomyopathy_Homo sapiens_hsa054140.76563048
84Regulation of autophagy_Homo sapiens_hsa041400.76461559
85Herpes simplex infection_Homo sapiens_hsa051680.75618545
86Carbohydrate digestion and absorption_Homo sapiens_hsa049730.75367381
87Thyroid hormone signaling pathway_Homo sapiens_hsa049190.74418831
88Notch signaling pathway_Homo sapiens_hsa043300.74347731
89Amoebiasis_Homo sapiens_hsa051460.73963077
90Allograft rejection_Homo sapiens_hsa053300.73027640
91SNARE interactions in vesicular transport_Homo sapiens_hsa041300.72938045
92FoxO signaling pathway_Homo sapiens_hsa040680.72397711
93Viral myocarditis_Homo sapiens_hsa054160.71102491
94Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.69604647
95Calcium signaling pathway_Homo sapiens_hsa040200.68052027
96Prolactin signaling pathway_Homo sapiens_hsa049170.67482156
97Insulin resistance_Homo sapiens_hsa049310.67008043
98Endocytosis_Homo sapiens_hsa041440.66956394
99Adipocytokine signaling pathway_Homo sapiens_hsa049200.66439594
100Amphetamine addiction_Homo sapiens_hsa050310.66309264
101Salmonella infection_Homo sapiens_hsa051320.66064684
102Acute myeloid leukemia_Homo sapiens_hsa052210.66046075
103Shigellosis_Homo sapiens_hsa051310.65411391
104Sphingolipid signaling pathway_Homo sapiens_hsa040710.65379239
105Colorectal cancer_Homo sapiens_hsa052100.64924617
106Graft-versus-host disease_Homo sapiens_hsa053320.64707717
107* Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.64662937
108Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.64598446
109Platelet activation_Homo sapiens_hsa046110.64374743
110Gap junction_Homo sapiens_hsa045400.64230267
111Cocaine addiction_Homo sapiens_hsa050300.63761031
112Rap1 signaling pathway_Homo sapiens_hsa040150.62683066
113Choline metabolism in cancer_Homo sapiens_hsa052310.62012971
114Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.61775535
115Antigen processing and presentation_Homo sapiens_hsa046120.61557364
116Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.61045035
117Leukocyte transendothelial migration_Homo sapiens_hsa046700.60820317
118NF-kappa B signaling pathway_Homo sapiens_hsa040640.60451416
119African trypanosomiasis_Homo sapiens_hsa051430.59955123
120Type I diabetes mellitus_Homo sapiens_hsa049400.59569347
121Central carbon metabolism in cancer_Homo sapiens_hsa052300.59001328
122Insulin signaling pathway_Homo sapiens_hsa049100.58618635
123Malaria_Homo sapiens_hsa051440.57921953
124Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.57660088
125Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.56171496

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