Rank | Gene Set | Z-score |
---|---|---|
1 | central nervous system myelination (GO:0022010) | 6.62138211 |
2 | axon ensheathment in central nervous system (GO:0032291) | 6.62138211 |
3 | locomotory exploration behavior (GO:0035641) | 5.91691125 |
4 | synaptic vesicle maturation (GO:0016188) | 5.56427478 |
5 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 5.52344049 |
6 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 5.11175259 |
7 | vocalization behavior (GO:0071625) | 5.09680456 |
8 | synaptic vesicle exocytosis (GO:0016079) | 4.87629913 |
9 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 4.82588196 |
10 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 4.81334543 |
11 | gamma-aminobutyric acid transport (GO:0015812) | 4.71583604 |
12 | cellular potassium ion homeostasis (GO:0030007) | 4.63488156 |
13 | regulation of glutamate receptor signaling pathway (GO:1900449) | 4.56947191 |
14 | layer formation in cerebral cortex (GO:0021819) | 4.50060926 |
15 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.48839708 |
16 | neuron cell-cell adhesion (GO:0007158) | 4.42290882 |
17 | neurotransmitter-gated ion channel clustering (GO:0072578) | 4.38081056 |
18 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 4.37998387 |
19 | exploration behavior (GO:0035640) | 4.36847292 |
20 | sodium ion export (GO:0071436) | 4.33843356 |
21 | * glutamate secretion (GO:0014047) | 4.29917675 |
22 | neurotransmitter secretion (GO:0007269) | 4.28412144 |
23 | astrocyte differentiation (GO:0048708) | 4.28300102 |
24 | protein localization to synapse (GO:0035418) | 4.24227243 |
25 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 4.17691329 |
26 | regulation of neuronal synaptic plasticity (GO:0048168) | 4.14149267 |
27 | neuronal action potential propagation (GO:0019227) | 4.11633164 |
28 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 4.11331045 |
29 | regulation of synapse structural plasticity (GO:0051823) | 4.03803684 |
30 | proline transport (GO:0015824) | 4.03446368 |
31 | L-amino acid import (GO:0043092) | 4.01589371 |
32 | regulation of synaptic vesicle transport (GO:1902803) | 3.98389451 |
33 | glutamate receptor signaling pathway (GO:0007215) | 3.96371465 |
34 | cGMP-mediated signaling (GO:0019934) | 3.96330051 |
35 | neuronal stem cell maintenance (GO:0097150) | 3.94018182 |
36 | synaptic transmission, glutamatergic (GO:0035249) | 3.90378601 |
37 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.87923130 |
38 | dendritic spine morphogenesis (GO:0060997) | 3.87823807 |
39 | negative regulation of oligodendrocyte differentiation (GO:0048715) | 3.85620978 |
40 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.84766220 |
41 | negative regulation of neurotransmitter transport (GO:0051589) | 3.80587677 |
42 | cell communication by electrical coupling (GO:0010644) | 3.77397630 |
43 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.70576139 |
44 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.63880384 |
45 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 3.62913029 |
46 | positive regulation of vascular permeability (GO:0043117) | 3.62859202 |
47 | neuron-neuron synaptic transmission (GO:0007270) | 3.58493955 |
48 | auditory behavior (GO:0031223) | 3.58442347 |
49 | amino acid import (GO:0043090) | 3.55831362 |
50 | neurotransmitter transport (GO:0006836) | 3.53180415 |
51 | establishment of nucleus localization (GO:0040023) | 3.52956446 |
52 | startle response (GO:0001964) | 3.51348456 |
53 | transmission of nerve impulse (GO:0019226) | 3.49406051 |
54 | postsynaptic membrane organization (GO:0001941) | 3.46743383 |
55 | establishment of mitochondrion localization (GO:0051654) | 3.45706813 |
56 | potassium ion import (GO:0010107) | 3.41972226 |
57 | neurotransmitter uptake (GO:0001504) | 3.40975082 |
58 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 3.38047086 |
59 | * long-term memory (GO:0007616) | 3.37978370 |
60 | positive regulation of membrane potential (GO:0045838) | 3.36534684 |
61 | dendrite morphogenesis (GO:0048813) | 3.35554285 |
62 | alanine transport (GO:0032328) | 3.33734778 |
63 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 3.33301330 |
64 | regulation of neurotransmitter levels (GO:0001505) | 3.33128761 |
65 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 3.32809743 |
66 | activation of protein kinase A activity (GO:0034199) | 3.32183322 |
67 | negative regulation of astrocyte differentiation (GO:0048712) | 3.32095897 |
68 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 3.30453698 |
69 | astrocyte development (GO:0014002) | 3.30178756 |
70 | neuron recognition (GO:0008038) | 3.29729702 |
71 | pyrimidine nucleobase catabolic process (GO:0006208) | 3.28762650 |
72 | neuromuscular process controlling balance (GO:0050885) | 3.26630835 |
73 | regulation of neurotransmitter uptake (GO:0051580) | 3.25937887 |
74 | cellular sodium ion homeostasis (GO:0006883) | 3.25653690 |
75 | * positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 3.24502249 |
76 | * regulation of synaptic plasticity (GO:0048167) | 3.23902158 |
77 | * regulation of synaptic transmission, glutamatergic (GO:0051966) | 3.22204563 |
78 | acidic amino acid transport (GO:0015800) | 3.21616897 |
79 | positive regulation of potassium ion transmembrane transport (GO:1901381) | 3.20647164 |
80 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.19252042 |
81 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.18158809 |
82 | regulation of dendritic spine morphogenesis (GO:0061001) | 3.17754232 |
83 | glycine transport (GO:0015816) | 3.17708811 |
84 | regulation of postsynaptic membrane potential (GO:0060078) | 3.16861492 |
85 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.16473842 |
86 | potassium ion homeostasis (GO:0055075) | 3.15901082 |
87 | axonal fasciculation (GO:0007413) | 3.14931209 |
88 | * response to auditory stimulus (GO:0010996) | 3.13019867 |
89 | synaptic vesicle endocytosis (GO:0048488) | 3.12904757 |
90 | regulation of penile erection (GO:0060405) | 3.12354314 |
91 | presynaptic membrane assembly (GO:0097105) | 3.11966067 |
92 | mechanosensory behavior (GO:0007638) | 3.11086725 |
93 | cerebellar granule cell differentiation (GO:0021707) | 3.07865762 |
94 | * long-term synaptic potentiation (GO:0060291) | 3.07713107 |
95 | central nervous system projection neuron axonogenesis (GO:0021952) | 3.03146046 |
96 | positive regulation of synapse maturation (GO:0090129) | 3.02638573 |
97 | positive regulation of synapse assembly (GO:0051965) | 3.02564816 |
98 | regulation of beta-amyloid formation (GO:1902003) | 3.00878399 |
99 | regulation of vesicle fusion (GO:0031338) | 3.00842785 |
100 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.99697203 |
101 | prepulse inhibition (GO:0060134) | 2.99606466 |
102 | innervation (GO:0060384) | 2.96952304 |
103 | cerebellar Purkinje cell differentiation (GO:0021702) | 2.94483682 |
104 | L-glutamate transport (GO:0015813) | 2.94374727 |
105 | synapse assembly (GO:0007416) | 2.94321372 |
106 | C4-dicarboxylate transport (GO:0015740) | 2.93641853 |
107 | membrane repolarization (GO:0086009) | 2.92816937 |
108 | positive regulation of dendritic spine development (GO:0060999) | 2.92424809 |
109 | cellular response to cholesterol (GO:0071397) | 2.92409202 |
110 | neuronal ion channel clustering (GO:0045161) | 2.91403659 |
111 | * regulation of neurotransmitter secretion (GO:0046928) | 2.89333874 |
112 | membrane hyperpolarization (GO:0060081) | 2.86350756 |
113 | membrane depolarization during action potential (GO:0086010) | 2.85970730 |
114 | neuromuscular process controlling posture (GO:0050884) | 2.84445303 |
115 | presynaptic membrane organization (GO:0097090) | 2.83384897 |
116 | response to histamine (GO:0034776) | 2.83216020 |
117 | photoreceptor cell differentiation (GO:0046530) | 2.82996875 |
118 | eye photoreceptor cell differentiation (GO:0001754) | 2.82996875 |
119 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 2.82891788 |
120 | cyclic-nucleotide-mediated signaling (GO:0019935) | 2.82207864 |
121 | nucleobase catabolic process (GO:0046113) | 2.81676195 |
122 | vascular smooth muscle contraction (GO:0014829) | 2.80995349 |
123 | regulation of fever generation (GO:0031620) | 2.80663127 |
124 | * positive regulation of synaptic transmission (GO:0050806) | 2.79638926 |
125 | * regulation of synaptic transmission (GO:0050804) | 2.78865547 |
126 | regulation of respiratory system process (GO:0044065) | 2.78769454 |
127 | * regulation of neurotransmitter transport (GO:0051588) | 2.78585625 |
128 | regulation of dendritic spine development (GO:0060998) | 2.78131932 |
129 | membrane depolarization (GO:0051899) | 2.77482599 |
130 | * learning (GO:0007612) | 2.77364137 |
131 | neuron projection regeneration (GO:0031102) | 2.76996577 |
132 | negative regulation of glial cell differentiation (GO:0045686) | 2.75870052 |
133 | axon regeneration (GO:0031103) | 2.75216125 |
134 | dermatan sulfate biosynthetic process (GO:0030208) | 2.74132889 |
135 | regulation of sensory perception of pain (GO:0051930) | 2.72040144 |
136 | regulation of sensory perception (GO:0051931) | 2.72040144 |
137 | myelination (GO:0042552) | 2.70862190 |
138 | positive regulation of potassium ion transport (GO:0043268) | 2.70813795 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.73467500 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.24549908 |
3 | * SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 3.08064410 |
4 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 3.05815491 |
5 | * JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.96008595 |
6 | * EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.64645666 |
7 | * RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.64645666 |
8 | * SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.61182437 |
9 | * REST_21632747_ChIP-Seq_MESCs_Mouse | 2.58170325 |
10 | * JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.56174620 |
11 | * SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.55469658 |
12 | * MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.54124538 |
13 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.51926146 |
14 | * SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.50633409 |
15 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.48499822 |
16 | * EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.38761453 |
17 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.34533360 |
18 | * EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.32927433 |
19 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.19716775 |
20 | * RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.19016634 |
21 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.19012027 |
22 | * EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.18583194 |
23 | * REST_18959480_ChIP-ChIP_MESCs_Mouse | 2.05135267 |
24 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.01495856 |
25 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.94354386 |
26 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.90889400 |
27 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.90686078 |
28 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.83154322 |
29 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.74178207 |
30 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.72779845 |
31 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.69564678 |
32 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.59112032 |
33 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.57143569 |
34 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.52887953 |
35 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.52556931 |
36 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.52422432 |
37 | * ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.49090468 |
38 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.42886275 |
39 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.40707359 |
40 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.40182741 |
41 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.38765031 |
42 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.32503303 |
43 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.31885778 |
44 | * PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.30751248 |
45 | P300_19829295_ChIP-Seq_ESCs_Human | 1.28877045 |
46 | * SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.28281541 |
47 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.27754960 |
48 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.27477950 |
49 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.27406791 |
50 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.26881546 |
51 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.26596141 |
52 | * AR_25329375_ChIP-Seq_VCAP_Human | 1.23791226 |
53 | * AR_19668381_ChIP-Seq_PC3_Human | 1.23750317 |
54 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.23192108 |
55 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.22203419 |
56 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.21565498 |
57 | STAT3_23295773_ChIP-Seq_U87_Human | 1.21256017 |
58 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.19876183 |
59 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.18843759 |
60 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.18478864 |
61 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.18450444 |
62 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.17696726 |
63 | * SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.16390807 |
64 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.16152743 |
65 | * RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.15984253 |
66 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.15041230 |
67 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.13960100 |
68 | * ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.12487832 |
69 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.12419301 |
70 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.12014487 |
71 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.10915261 |
72 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.09830202 |
73 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.09058907 |
74 | * DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.08129110 |
75 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.07184152 |
76 | * TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.06761655 |
77 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.06659318 |
78 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.06171005 |
79 | * TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.06020442 |
80 | * YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.05955530 |
81 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.05170442 |
82 | * TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.05049446 |
83 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.04859899 |
84 | * NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.04651345 |
85 | RXR_22108803_ChIP-Seq_LS180_Human | 1.03440224 |
86 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.02955241 |
87 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.02579479 |
88 | TCF4_23295773_ChIP-Seq_U87_Human | 1.02575616 |
89 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.01541054 |
90 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.00800218 |
91 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.00800218 |
92 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.00788327 |
93 | * SOX9_26525672_Chip-Seq_HEART_Mouse | 1.00293960 |
94 | KDM2B_26808549_Chip-Seq_K562_Human | 1.00020900 |
95 | * TBX3_20139965_ChIP-Seq_MESCs_Mouse | 0.98942434 |
96 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.98278793 |
97 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.97327794 |
98 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.96800385 |
99 | TP53_16413492_ChIP-PET_HCT116_Human | 0.96373863 |
100 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 0.96025373 |
101 | * TBX3_20139965_ChIP-Seq_ESCs_Mouse | 0.95951045 |
102 | * SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.95817268 |
103 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 0.95794192 |
104 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.94352216 |
105 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.94069676 |
106 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.93699903 |
107 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 0.93601455 |
108 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 0.93493707 |
109 | * RUNX2_22187159_ChIP-Seq_PCA_Human | 0.93380690 |
110 | KDM2B_26808549_Chip-Seq_REH_Human | 0.92870447 |
111 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.92507357 |
112 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.90824887 |
113 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.89992604 |
114 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.89652247 |
115 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.89215230 |
116 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.88886647 |
117 | * BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.88181134 |
118 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.88011945 |
119 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.87767654 |
120 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.86730496 |
121 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.85936469 |
122 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.85936469 |
123 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 0.85441033 |
124 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.84546023 |
125 | * TP53_18474530_ChIP-ChIP_U2OS_Human | 0.84310788 |
126 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.84138299 |
127 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.83663508 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * MP0004859_abnormal_synaptic_plasticity | 5.85531167 |
2 | MP0003136_yellow_coat_color | 5.79584362 |
3 | MP0003880_abnormal_central_pattern | 4.10716766 |
4 | * MP0003635_abnormal_synaptic_transmissio | 4.03854970 |
5 | MP0004270_analgesia | 3.56528054 |
6 | MP0009745_abnormal_behavioral_response | 3.33920963 |
7 | * MP0002063_abnormal_learning/memory/cond | 3.21751264 |
8 | MP0009046_muscle_twitch | 3.09343926 |
9 | * MP0002064_seizures | 3.08913208 |
10 | MP0005423_abnormal_somatic_nervous | 3.02137394 |
11 | MP0001486_abnormal_startle_reflex | 2.80068344 |
12 | * MP0002572_abnormal_emotion/affect_behav | 2.71512192 |
13 | MP0001968_abnormal_touch/_nociception | 2.68745923 |
14 | MP0002734_abnormal_mechanical_nocicepti | 2.58308634 |
15 | MP0003329_amyloid_beta_deposits | 2.48651529 |
16 | MP0002272_abnormal_nervous_system | 2.47344849 |
17 | MP0009780_abnormal_chondrocyte_physiolo | 2.42965937 |
18 | MP0001501_abnormal_sleep_pattern | 2.30060228 |
19 | MP0005646_abnormal_pituitary_gland | 2.25820035 |
20 | MP0001440_abnormal_grooming_behavior | 2.18747410 |
21 | MP0002822_catalepsy | 2.15426586 |
22 | MP0002909_abnormal_adrenal_gland | 2.11962023 |
23 | MP0004885_abnormal_endolymph | 2.09571584 |
24 | MP0008569_lethality_at_weaning | 2.08974021 |
25 | MP0002733_abnormal_thermal_nociception | 2.04689684 |
26 | MP0002736_abnormal_nociception_after | 2.01712288 |
27 | MP0003690_abnormal_glial_cell | 2.00244208 |
28 | MP0000778_abnormal_nervous_system | 1.92650916 |
29 | MP0001970_abnormal_pain_threshold | 1.89751254 |
30 | MP0005645_abnormal_hypothalamus_physiol | 1.88938167 |
31 | MP0002557_abnormal_social/conspecific_i | 1.86699646 |
32 | * MP0002067_abnormal_sensory_capabilities | 1.86391503 |
33 | MP0002735_abnormal_chemical_nociception | 1.77568186 |
34 | MP0001984_abnormal_olfaction | 1.75751091 |
35 | MP0004924_abnormal_behavior | 1.63167271 |
36 | MP0005386_behavior/neurological_phenoty | 1.63167271 |
37 | MP0003633_abnormal_nervous_system | 1.59082172 |
38 | MP0001502_abnormal_circadian_rhythm | 1.56608079 |
39 | * MP0004811_abnormal_neuron_physiology | 1.55202674 |
40 | * MP0000955_abnormal_spinal_cord | 1.51868994 |
41 | * MP0002184_abnormal_innervation | 1.47172257 |
42 | * MP0004858_abnormal_nervous_system | 1.46911438 |
43 | * MP0000026_abnormal_inner_ear | 1.46012240 |
44 | * MP0002882_abnormal_neuron_morphology | 1.43026933 |
45 | MP0005248_abnormal_Harderian_gland | 1.39832567 |
46 | * MP0002066_abnormal_motor_capabilities/c | 1.38475124 |
47 | MP0003631_nervous_system_phenotype | 1.35227051 |
48 | MP0003878_abnormal_ear_physiology | 1.32951267 |
49 | MP0005377_hearing/vestibular/ear_phenot | 1.32951267 |
50 | MP0001958_emphysema | 1.28187164 |
51 | * MP0003634_abnormal_glial_cell | 1.27177625 |
52 | MP0006276_abnormal_autonomic_nervous | 1.25006439 |
53 | MP0000604_amyloidosis | 1.24155929 |
54 | MP0003879_abnormal_hair_cell | 1.23569504 |
55 | MP0005174_abnormal_tail_pigmentation | 1.23179835 |
56 | MP0004142_abnormal_muscle_tone | 1.21196170 |
57 | * MP0002152_abnormal_brain_morphology | 1.17432870 |
58 | MP0003075_altered_response_to | 1.15071688 |
59 | MP0000566_synostosis | 1.13281695 |
60 | MP0003632_abnormal_nervous_system | 1.12885132 |
61 | MP0005167_abnormal_blood-brain_barrier | 1.12388426 |
62 | MP0003787_abnormal_imprinting | 1.11368573 |
63 | MP0001177_atelectasis | 1.05775775 |
64 | MP0000013_abnormal_adipose_tissue | 1.05378890 |
65 | MP0001905_abnormal_dopamine_level | 1.04354592 |
66 | MP0003283_abnormal_digestive_organ | 1.02789009 |
67 | MP0002229_neurodegeneration | 0.99672846 |
68 | MP0001529_abnormal_vocalization | 0.93772365 |
69 | MP0003122_maternal_imprinting | 0.93502102 |
70 | * MP0005551_abnormal_eye_electrophysiolog | 0.93133726 |
71 | MP0001485_abnormal_pinna_reflex | 0.91296048 |
72 | MP0008872_abnormal_physiological_respon | 0.90958582 |
73 | * MP0002069_abnormal_eating/drinking_beha | 0.90315035 |
74 | MP0005535_abnormal_body_temperature | 0.89708764 |
75 | MP0001346_abnormal_lacrimal_gland | 0.89581092 |
76 | MP0000751_myopathy | 0.88558429 |
77 | * MP0000920_abnormal_myelination | 0.86599689 |
78 | MP0000631_abnormal_neuroendocrine_gland | 0.85271200 |
79 | MP0001299_abnormal_eye_distance/ | 0.85006469 |
80 | MP0005187_abnormal_penis_morphology | 0.84096032 |
81 | MP0002249_abnormal_larynx_morphology | 0.84090098 |
82 | MP0000569_abnormal_digit_pigmentation | 0.82565603 |
83 | MP0003137_abnormal_impulse_conducting | 0.81408702 |
84 | MP0008961_abnormal_basal_metabolism | 0.81244318 |
85 | MP0004133_heterotaxia | 0.81039199 |
86 | MP0008874_decreased_physiological_sensi | 0.80559461 |
87 | MP0003172_abnormal_lysosome_physiology | 0.80046298 |
88 | MP0004742_abnormal_vestibular_system | 0.79927120 |
89 | MP0002095_abnormal_skin_pigmentation | 0.79320415 |
90 | * MP0001963_abnormal_hearing_physiology | 0.79206346 |
91 | MP0004085_abnormal_heartbeat | 0.75363970 |
92 | MP0005394_taste/olfaction_phenotype | 0.74989303 |
93 | MP0005499_abnormal_olfactory_system | 0.74989303 |
94 | MP0004215_abnormal_myocardial_fiber | 0.74497495 |
95 | MP0001188_hyperpigmentation | 0.74293417 |
96 | MP0004043_abnormal_pH_regulation | 0.73364039 |
97 | MP0005595_abnormal_vascular_smooth | 0.73281377 |
98 | MP0006072_abnormal_retinal_apoptosis | 0.71676976 |
99 | * MP0002752_abnormal_somatic_nervous | 0.71242844 |
100 | MP0004130_abnormal_muscle_cell | 0.70303615 |
101 | MP0004145_abnormal_muscle_electrophysio | 0.69824290 |
102 | MP0003938_abnormal_ear_development | 0.68264771 |
103 | MP0000579_abnormal_nail_morphology | 0.67103391 |
104 | MP0000762_abnormal_tongue_morphology | 0.65229647 |
105 | MP0002653_abnormal_ependyma_morphology | 0.64360291 |
106 | MP0002751_abnormal_autonomic_nervous | 0.64255314 |
107 | MP0005253_abnormal_eye_physiology | 0.64224665 |
108 | MP0002089_abnormal_postnatal_growth/wei | 0.64207290 |
109 | MP0003183_abnormal_peptide_metabolism | 0.64117071 |
110 | MP0010386_abnormal_urinary_bladder | 0.63804010 |
111 | MP0005623_abnormal_meninges_morphology | 0.63223051 |
112 | MP0004233_abnormal_muscle_weight | 0.62970128 |
113 | MP0001664_abnormal_digestion | 0.62706370 |
114 | MP0000534_abnormal_ureter_morphology | 0.62110195 |
115 | * MP0002090_abnormal_vision | 0.61486287 |
116 | MP0000647_abnormal_sebaceous_gland | 0.61335783 |
117 | MP0005379_endocrine/exocrine_gland_phen | 0.59527826 |
118 | MP0001270_distended_abdomen | 0.58683345 |
119 | * MP0010769_abnormal_survival | 0.58180891 |
120 | MP0002928_abnormal_bile_duct | 0.57786069 |
121 | * MP0002638_abnormal_pupillary_reflex | 0.57534721 |
122 | * MP0005195_abnormal_posterior_eye | 0.56076632 |
123 | * MP0010770_preweaning_lethality | 0.55246818 |
124 | * MP0003861_abnormal_nervous_system | 0.54771368 |
125 | * MP0001943_abnormal_respiration | 0.54090931 |
126 | MP0005171_absent_coat_pigmentation | 0.52300659 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Focal motor seizures (HP:0011153) | 6.89911353 |
2 | Myokymia (HP:0002411) | 5.93356835 |
3 | Focal seizures (HP:0007359) | 5.12832747 |
4 | Megalencephaly (HP:0001355) | 4.77735984 |
5 | Epileptic encephalopathy (HP:0200134) | 4.68491416 |
6 | Visual hallucinations (HP:0002367) | 4.57124717 |
7 | Split foot (HP:0001839) | 4.17278646 |
8 | Progressive cerebellar ataxia (HP:0002073) | 4.05544830 |
9 | Action tremor (HP:0002345) | 3.96915645 |
10 | Supranuclear gaze palsy (HP:0000605) | 3.96070915 |
11 | Neurofibrillary tangles (HP:0002185) | 3.95569189 |
12 | Generalized tonic-clonic seizures (HP:0002069) | 3.72321470 |
13 | Atonic seizures (HP:0010819) | 3.71566791 |
14 | Absence seizures (HP:0002121) | 3.67106029 |
15 | Febrile seizures (HP:0002373) | 3.64641331 |
16 | Diplopia (HP:0000651) | 3.49324768 |
17 | Abnormality of binocular vision (HP:0011514) | 3.49324768 |
18 | Hemiparesis (HP:0001269) | 3.47233381 |
19 | Cerebral inclusion bodies (HP:0100314) | 3.39888803 |
20 | Dialeptic seizures (HP:0011146) | 3.36689211 |
21 | Dysdiadochokinesis (HP:0002075) | 3.31172501 |
22 | Aplasia involving bones of the extremities (HP:0009825) | 3.30833729 |
23 | Aplasia involving bones of the upper limbs (HP:0009823) | 3.30833729 |
24 | Aplasia of the phalanges of the hand (HP:0009802) | 3.30833729 |
25 | Hemiplegia (HP:0002301) | 3.24308562 |
26 | Depression (HP:0000716) | 3.18798826 |
27 | Coronal craniosynostosis (HP:0004440) | 3.16883388 |
28 | Ankle clonus (HP:0011448) | 3.12084562 |
29 | Postural instability (HP:0002172) | 3.09480838 |
30 | Papilledema (HP:0001085) | 3.06662662 |
31 | Hyperventilation (HP:0002883) | 3.06481050 |
32 | Broad-based gait (HP:0002136) | 3.03144971 |
33 | Truncal ataxia (HP:0002078) | 3.01856152 |
34 | Septo-optic dysplasia (HP:0100842) | 2.99488178 |
35 | Poor eye contact (HP:0000817) | 2.99450577 |
36 | Heterochromia iridis (HP:0001100) | 2.95878300 |
37 | Anxiety (HP:0000739) | 2.95796611 |
38 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.81959854 |
39 | Dysmetria (HP:0001310) | 2.81358365 |
40 | Abnormal social behavior (HP:0012433) | 2.81252181 |
41 | Impaired social interactions (HP:0000735) | 2.81252181 |
42 | Intention tremor (HP:0002080) | 2.77930905 |
43 | Mutism (HP:0002300) | 2.77405417 |
44 | Gaze-evoked nystagmus (HP:0000640) | 2.77244318 |
45 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.76328364 |
46 | Genetic anticipation (HP:0003743) | 2.72319271 |
47 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.66553951 |
48 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.66553951 |
49 | * Abnormal eating behavior (HP:0100738) | 2.65996707 |
50 | White forelock (HP:0002211) | 2.64379622 |
51 | Drooling (HP:0002307) | 2.58810687 |
52 | Excessive salivation (HP:0003781) | 2.58810687 |
53 | Epileptiform EEG discharges (HP:0011182) | 2.55379787 |
54 | Abnormality of the diencephalon (HP:0010662) | 2.54405240 |
55 | Oligodactyly (hands) (HP:0001180) | 2.54254404 |
56 | Status epilepticus (HP:0002133) | 2.53556291 |
57 | EEG with generalized epileptiform discharges (HP:0011198) | 2.51863395 |
58 | Neonatal short-limb short stature (HP:0008921) | 2.46463112 |
59 | Impaired smooth pursuit (HP:0007772) | 2.44011866 |
60 | Hypsarrhythmia (HP:0002521) | 2.43481384 |
61 | Patchy hypopigmentation of hair (HP:0011365) | 2.41508137 |
62 | Progressive inability to walk (HP:0002505) | 2.39460623 |
63 | Bradykinesia (HP:0002067) | 2.39291203 |
64 | Clumsiness (HP:0002312) | 2.36732852 |
65 | Scanning speech (HP:0002168) | 2.34895202 |
66 | Torticollis (HP:0000473) | 2.31740821 |
67 | Stereotypic behavior (HP:0000733) | 2.30402213 |
68 | Spastic gait (HP:0002064) | 2.28587757 |
69 | Large for gestational age (HP:0001520) | 2.26342600 |
70 | Hammertoe (HP:0001765) | 2.26166771 |
71 | Lower limb muscle weakness (HP:0007340) | 2.25043090 |
72 | True hermaphroditism (HP:0010459) | 2.24907824 |
73 | Urinary urgency (HP:0000012) | 2.24268500 |
74 | Abnormality of ocular smooth pursuit (HP:0000617) | 2.21580138 |
75 | Alacrima (HP:0000522) | 2.20615513 |
76 | Turricephaly (HP:0000262) | 2.16647883 |
77 | Focal dystonia (HP:0004373) | 2.15612224 |
78 | Amblyopia (HP:0000646) | 2.14371483 |
79 | Ulnar claw (HP:0001178) | 2.13685381 |
80 | Insomnia (HP:0100785) | 2.12754141 |
81 | Abnormal auditory evoked potentials (HP:0006958) | 2.12056373 |
82 | Hepatoblastoma (HP:0002884) | 2.09547335 |
83 | Pheochromocytoma (HP:0002666) | 2.09240928 |
84 | Agitation (HP:0000713) | 2.08495727 |
85 | Obstructive sleep apnea (HP:0002870) | 2.06861456 |
86 | Cutaneous finger syndactyly (HP:0010554) | 2.04781832 |
87 | Neuronal loss in central nervous system (HP:0002529) | 2.03903714 |
88 | Generalized myoclonic seizures (HP:0002123) | 2.02442123 |
89 | Oligodactyly (HP:0012165) | 2.00582729 |
90 | Impaired vibratory sensation (HP:0002495) | 2.00247959 |
91 | Optic nerve hypoplasia (HP:0000609) | 1.96465454 |
92 | Gait ataxia (HP:0002066) | 1.94802119 |
93 | Wide anterior fontanel (HP:0000260) | 1.94770395 |
94 | Termporal pattern (HP:0011008) | 1.94182731 |
95 | Insidious onset (HP:0003587) | 1.94182731 |
96 | Ventricular fibrillation (HP:0001663) | 1.93968739 |
97 | Absent speech (HP:0001344) | 1.92123104 |
98 | Limb dystonia (HP:0002451) | 1.91566244 |
99 | Blue irides (HP:0000635) | 1.91290602 |
100 | Bronchomalacia (HP:0002780) | 1.89291311 |
101 | Fibular hypoplasia (HP:0003038) | 1.88489060 |
102 | Rigidity (HP:0002063) | 1.88487469 |
103 | Esophageal atresia (HP:0002032) | 1.86764868 |
104 | Broad foot (HP:0001769) | 1.86092711 |
105 | Psychosis (HP:0000709) | 1.85819348 |
106 | Specific learning disability (HP:0001328) | 1.85177976 |
107 | Inability to walk (HP:0002540) | 1.84561786 |
108 | Craniofacial dystonia (HP:0012179) | 1.84368743 |
109 | Abnormality of the lower motor neuron (HP:0002366) | 1.84184268 |
110 | Aplasia/Hypoplasia of the fibula (HP:0006492) | 1.84011608 |
111 | Hypoplasia of the corpus callosum (HP:0002079) | 1.83298731 |
112 | Abnormality of the 4th metacarpal (HP:0010012) | 1.82864792 |
113 | Fetal akinesia sequence (HP:0001989) | 1.82549179 |
114 | Abnormality of the ischium (HP:0003174) | 1.82344654 |
115 | Morphological abnormality of the pyramidal tract (HP:0002062) | 1.81608722 |
116 | Increased circulating renin level (HP:0000848) | 1.81431789 |
117 | Abnormality of the corticospinal tract (HP:0002492) | 1.80602366 |
118 | Steppage gait (HP:0003376) | 1.80369664 |
119 | Abnormality of saccadic eye movements (HP:0000570) | 1.78408096 |
120 | Cutaneous syndactyly (HP:0012725) | 1.78237205 |
121 | Tetraplegia (HP:0002445) | 1.77471505 |
122 | Clonus (HP:0002169) | 1.77255740 |
123 | Abnormality of salivation (HP:0100755) | 1.76821693 |
124 | Partial duplication of thumb phalanx (HP:0009944) | 1.75701459 |
125 | Abnormal ciliary motility (HP:0012262) | 1.75525029 |
126 | Vertebral arch anomaly (HP:0008438) | 1.75405614 |
127 | Neuroendocrine neoplasm (HP:0100634) | 1.74469445 |
128 | Peripheral hypomyelination (HP:0007182) | 1.73818935 |
129 | Congenital primary aphakia (HP:0007707) | 1.73069063 |
130 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 1.72370477 |
131 | Dysmetric saccades (HP:0000641) | 1.72197157 |
132 | Decreased lacrimation (HP:0000633) | 1.72160855 |
133 | Annular pancreas (HP:0001734) | 1.71956324 |
134 | Cortical dysplasia (HP:0002539) | 1.71227475 |
135 | Anophthalmia (HP:0000528) | 1.71124708 |
136 | Morphological abnormality of the inner ear (HP:0011390) | 1.71039606 |
137 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.70827096 |
138 | Gait imbalance (HP:0002141) | 1.70687786 |
139 | Thickened helices (HP:0000391) | 1.70196974 |
140 | Aqueductal stenosis (HP:0002410) | 1.69679884 |
141 | Pointed chin (HP:0000307) | 1.69290057 |
142 | Genital tract atresia (HP:0001827) | 1.68284349 |
143 | Postural tremor (HP:0002174) | 1.68227187 |
144 | Amyotrophic lateral sclerosis (HP:0007354) | 1.67763833 |
145 | Sleep apnea (HP:0010535) | 1.67748358 |
146 | Vaginal atresia (HP:0000148) | 1.65477829 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EPHA4 | 4.28089783 |
2 | NTRK3 | 4.10833448 |
3 | MAP3K9 | 3.51333822 |
4 | MARK1 | 3.51111243 |
5 | MAP3K4 | 2.78686471 |
6 | PRKD3 | 2.66145275 |
7 | MAPK15 | 2.63174878 |
8 | MINK1 | 2.51465412 |
9 | MAP2K7 | 2.34641114 |
10 | LMTK2 | 2.32713388 |
11 | TNIK | 2.27927764 |
12 | PAK6 | 2.23587394 |
13 | EPHA3 | 2.23414049 |
14 | PHKG2 | 2.08083085 |
15 | PHKG1 | 2.08083085 |
16 | DAPK2 | 2.07182141 |
17 | NTRK1 | 1.96082479 |
18 | * NTRK2 | 1.86824467 |
19 | CASK | 1.83027514 |
20 | KSR2 | 1.81664586 |
21 | CAMKK1 | 1.77317993 |
22 | MOS | 1.65772908 |
23 | MAP2K4 | 1.63364424 |
24 | * CDK5 | 1.49724168 |
25 | BCR | 1.46853113 |
26 | MAPK13 | 1.42638289 |
27 | RIPK4 | 1.35621760 |
28 | KSR1 | 1.34035845 |
29 | STK38 | 1.28047119 |
30 | SGK494 | 1.26947481 |
31 | SGK223 | 1.26947481 |
32 | PRKCG | 1.25611841 |
33 | SGK2 | 1.21772559 |
34 | STK39 | 1.21318239 |
35 | TYRO3 | 1.20057176 |
36 | EPHB2 | 1.18636927 |
37 | PNCK | 1.18441395 |
38 | SIK2 | 1.18095621 |
39 | PLK2 | 1.15490016 |
40 | EPHB1 | 1.15189695 |
41 | MAP3K12 | 1.12015625 |
42 | PRPF4B | 1.09561464 |
43 | FES | 1.08805029 |
44 | MAP3K2 | 1.06279334 |
45 | SGK3 | 1.05199223 |
46 | PKN1 | 1.03823693 |
47 | GRK5 | 1.03204865 |
48 | UHMK1 | 1.01500132 |
49 | PRKCH | 1.00955591 |
50 | TSSK6 | 1.00916526 |
51 | CAMKK2 | 1.00760414 |
52 | DAPK1 | 1.00093334 |
53 | CAMK2A | 0.93960091 |
54 | WNK4 | 0.91873870 |
55 | PINK1 | 0.90347647 |
56 | MAP3K13 | 0.90308003 |
57 | PAK3 | 0.89567031 |
58 | LATS2 | 0.88351116 |
59 | RET | 0.83447345 |
60 | CDK15 | 0.83380826 |
61 | CAMK1 | 0.83051804 |
62 | CDK18 | 0.82613880 |
63 | ARAF | 0.82521230 |
64 | DYRK2 | 0.82319025 |
65 | CAMK1G | 0.82294636 |
66 | STK11 | 0.82120714 |
67 | CDK19 | 0.81067890 |
68 | CDK14 | 0.80616573 |
69 | CDK3 | 0.79810318 |
70 | CSNK1A1L | 0.78783530 |
71 | SGK1 | 0.78172614 |
72 | DYRK1A | 0.75452361 |
73 | CSNK1G3 | 0.75215578 |
74 | CAMK2B | 0.72863317 |
75 | MARK2 | 0.71253426 |
76 | CDK11A | 0.70834246 |
77 | ALK | 0.66254436 |
78 | TAOK1 | 0.66216063 |
79 | CSNK1G1 | 0.65216234 |
80 | CDC42BPA | 0.65000309 |
81 | CSNK1G2 | 0.63968515 |
82 | PRKCE | 0.63691400 |
83 | NEK6 | 0.62774915 |
84 | ERBB2 | 0.61863893 |
85 | FGFR2 | 0.60266378 |
86 | MUSK | 0.58987784 |
87 | FGR | 0.58891258 |
88 | NEK9 | 0.57353391 |
89 | RPS6KA3 | 0.55786607 |
90 | SCYL2 | 0.54604883 |
91 | PRKCZ | 0.54000621 |
92 | RAF1 | 0.53598542 |
93 | ROCK2 | 0.52997366 |
94 | PAK2 | 0.51306763 |
95 | TRIB3 | 0.50737717 |
96 | DMPK | 0.50370239 |
97 | PDPK1 | 0.50164027 |
98 | CAMK2G | 0.49871747 |
99 | PDK1 | 0.49297307 |
100 | BCKDK | 0.48853276 |
101 | ERBB3 | 0.48533218 |
102 | FYN | 0.48205131 |
103 | CAMK2D | 0.48006773 |
104 | TNK2 | 0.47911144 |
105 | MAPK10 | 0.47274720 |
106 | OXSR1 | 0.47048717 |
107 | BMPR1B | 0.46717363 |
108 | MAP3K1 | 0.46091050 |
109 | WNK1 | 0.45608080 |
110 | MAPK12 | 0.45502489 |
111 | ROCK1 | 0.44695302 |
112 | BMPR2 | 0.43108922 |
113 | YES1 | 0.43046093 |
114 | PDGFRB | 0.41908958 |
115 | RIPK1 | 0.41192367 |
116 | PTK2B | 0.39720153 |
117 | SIK1 | 0.37500968 |
118 | PDGFRA | 0.37293687 |
119 | WNK3 | 0.36772890 |
120 | WEE1 | 0.36749754 |
121 | FER | 0.36039796 |
122 | ICK | 0.35935136 |
123 | MAP3K7 | 0.35251602 |
124 | PRKG1 | 0.34645234 |
125 | MET | 0.34595552 |
126 | MAP2K1 | 0.34534493 |
127 | PRKCA | 0.33312790 |
128 | FGFR1 | 0.29911076 |
129 | BMX | 0.28715580 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nicotine addiction_Homo sapiens_hsa05033 | 3.49927976 |
2 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.96014368 |
3 | GABAergic synapse_Homo sapiens_hsa04727 | 2.83396234 |
4 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.78852220 |
5 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.55107883 |
6 | Circadian entrainment_Homo sapiens_hsa04713 | 2.52839777 |
7 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.45581204 |
8 | Olfactory transduction_Homo sapiens_hsa04740 | 2.40566297 |
9 | Morphine addiction_Homo sapiens_hsa05032 | 2.38667504 |
10 | Long-term potentiation_Homo sapiens_hsa04720 | 2.28960367 |
11 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.20429645 |
12 | Salivary secretion_Homo sapiens_hsa04970 | 2.17003305 |
13 | Insulin secretion_Homo sapiens_hsa04911 | 2.15152800 |
14 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.12219500 |
15 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.96935705 |
16 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.93271469 |
17 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.90480596 |
18 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.72632523 |
19 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.65107043 |
20 | Cocaine addiction_Homo sapiens_hsa05030 | 1.63055379 |
21 | Renin secretion_Homo sapiens_hsa04924 | 1.62799064 |
22 | Taste transduction_Homo sapiens_hsa04742 | 1.60010080 |
23 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.57422067 |
24 | Long-term depression_Homo sapiens_hsa04730 | 1.49934244 |
25 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.48145660 |
26 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.45883735 |
27 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.44764368 |
28 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.40688743 |
29 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.40461268 |
30 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.30654092 |
31 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.26598037 |
32 | Gap junction_Homo sapiens_hsa04540 | 1.25267993 |
33 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.24089153 |
34 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.19248178 |
35 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.15023481 |
36 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.14017724 |
37 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.09196225 |
38 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.07453229 |
39 | Melanogenesis_Homo sapiens_hsa04916 | 1.04641671 |
40 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.04174616 |
41 | Axon guidance_Homo sapiens_hsa04360 | 1.03948795 |
42 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.03774190 |
43 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.00404146 |
44 | Glioma_Homo sapiens_hsa05214 | 0.99035941 |
45 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.98822719 |
46 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.96433352 |
47 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.95184235 |
48 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.94540369 |
49 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.93920716 |
50 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.93686979 |
51 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.92684352 |
52 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.91886398 |
53 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.89156460 |
54 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.87849990 |
55 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.87473432 |
56 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.86497107 |
57 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.86458049 |
58 | Bile secretion_Homo sapiens_hsa04976 | 0.84908478 |
59 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.82455217 |
60 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.79462329 |
61 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.79282732 |
62 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.78846628 |
63 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.78536289 |
64 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.78103121 |
65 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.78057543 |
66 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.75788079 |
67 | Circadian rhythm_Homo sapiens_hsa04710 | 0.75022312 |
68 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.74883262 |
69 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.73844705 |
70 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.70348359 |
71 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.68878398 |
72 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.67194092 |
73 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.65162614 |
74 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.65115938 |
75 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.63884361 |
76 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.63304634 |
77 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.62878804 |
78 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.61944091 |
79 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.61798346 |
80 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.59953942 |
81 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.59850237 |
82 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.59511718 |
83 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.58772126 |
84 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.56045816 |
85 | Tight junction_Homo sapiens_hsa04530 | 0.54598683 |
86 | Histidine metabolism_Homo sapiens_hsa00340 | 0.54250750 |
87 | * MAPK signaling pathway_Homo sapiens_hsa04010 | 0.54138356 |
88 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.54076828 |
89 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.51938804 |
90 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.51838539 |
91 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.51777219 |
92 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.49223815 |
93 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.48959136 |
94 | Colorectal cancer_Homo sapiens_hsa05210 | 0.47038203 |
95 | Prion diseases_Homo sapiens_hsa05020 | 0.47001950 |
96 | Adherens junction_Homo sapiens_hsa04520 | 0.45489754 |
97 | * Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.44365682 |
98 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.43871341 |
99 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.41090909 |
100 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.40860882 |
101 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.40812860 |
102 | Phototransduction_Homo sapiens_hsa04744 | 0.40583415 |
103 | Endometrial cancer_Homo sapiens_hsa05213 | 0.39632248 |
104 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.39320767 |
105 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.39280786 |
106 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.39160435 |
107 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.38962166 |
108 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.38392593 |
109 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.38067819 |
110 | Mineral absorption_Homo sapiens_hsa04978 | 0.37532954 |
111 | Endocytosis_Homo sapiens_hsa04144 | 0.37527867 |
112 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.35918583 |
113 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.35874926 |
114 | * Alcoholism_Homo sapiens_hsa05034 | 0.31974195 |
115 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.31207896 |
116 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.31082827 |
117 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.29646864 |
118 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.29549593 |
119 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.28970714 |
120 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.26232783 |