NTRK2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1central nervous system myelination (GO:0022010)6.62138211
2axon ensheathment in central nervous system (GO:0032291)6.62138211
3locomotory exploration behavior (GO:0035641)5.91691125
4synaptic vesicle maturation (GO:0016188)5.56427478
5regulation of short-term neuronal synaptic plasticity (GO:0048172)5.52344049
6positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.11175259
7vocalization behavior (GO:0071625)5.09680456
8synaptic vesicle exocytosis (GO:0016079)4.87629913
9positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.82588196
10regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.81334543
11gamma-aminobutyric acid transport (GO:0015812)4.71583604
12cellular potassium ion homeostasis (GO:0030007)4.63488156
13regulation of glutamate receptor signaling pathway (GO:1900449)4.56947191
14layer formation in cerebral cortex (GO:0021819)4.50060926
15regulation of synaptic vesicle exocytosis (GO:2000300)4.48839708
16neuron cell-cell adhesion (GO:0007158)4.42290882
17neurotransmitter-gated ion channel clustering (GO:0072578)4.38081056
18ionotropic glutamate receptor signaling pathway (GO:0035235)4.37998387
19exploration behavior (GO:0035640)4.36847292
20sodium ion export (GO:0071436)4.33843356
21* glutamate secretion (GO:0014047)4.29917675
22neurotransmitter secretion (GO:0007269)4.28412144
23astrocyte differentiation (GO:0048708)4.28300102
24protein localization to synapse (GO:0035418)4.24227243
25regulation of long-term neuronal synaptic plasticity (GO:0048169)4.17691329
26regulation of neuronal synaptic plasticity (GO:0048168)4.14149267
27neuronal action potential propagation (GO:0019227)4.11633164
28synaptic vesicle docking involved in exocytosis (GO:0016081)4.11331045
29regulation of synapse structural plasticity (GO:0051823)4.03803684
30proline transport (GO:0015824)4.03446368
31L-amino acid import (GO:0043092)4.01589371
32regulation of synaptic vesicle transport (GO:1902803)3.98389451
33glutamate receptor signaling pathway (GO:0007215)3.96371465
34cGMP-mediated signaling (GO:0019934)3.96330051
35neuronal stem cell maintenance (GO:0097150)3.94018182
36synaptic transmission, glutamatergic (GO:0035249)3.90378601
37regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.87923130
38dendritic spine morphogenesis (GO:0060997)3.87823807
39negative regulation of oligodendrocyte differentiation (GO:0048715)3.85620978
40membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.84766220
41negative regulation of neurotransmitter transport (GO:0051589)3.80587677
42cell communication by electrical coupling (GO:0010644)3.77397630
43cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.70576139
44positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.63880384
45negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.62913029
46positive regulation of vascular permeability (GO:0043117)3.62859202
47neuron-neuron synaptic transmission (GO:0007270)3.58493955
48auditory behavior (GO:0031223)3.58442347
49amino acid import (GO:0043090)3.55831362
50neurotransmitter transport (GO:0006836)3.53180415
51establishment of nucleus localization (GO:0040023)3.52956446
52startle response (GO:0001964)3.51348456
53transmission of nerve impulse (GO:0019226)3.49406051
54postsynaptic membrane organization (GO:0001941)3.46743383
55establishment of mitochondrion localization (GO:0051654)3.45706813
56potassium ion import (GO:0010107)3.41972226
57neurotransmitter uptake (GO:0001504)3.40975082
58positive regulation of synaptic transmission, GABAergic (GO:0032230)3.38047086
59* long-term memory (GO:0007616)3.37978370
60positive regulation of membrane potential (GO:0045838)3.36534684
61dendrite morphogenesis (GO:0048813)3.35554285
62alanine transport (GO:0032328)3.33734778
63regulation of excitatory postsynaptic membrane potential (GO:0060079)3.33301330
64regulation of neurotransmitter levels (GO:0001505)3.33128761
65negative regulation of synaptic transmission, GABAergic (GO:0032229)3.32809743
66activation of protein kinase A activity (GO:0034199)3.32183322
67negative regulation of astrocyte differentiation (GO:0048712)3.32095897
68regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.30453698
69astrocyte development (GO:0014002)3.30178756
70neuron recognition (GO:0008038)3.29729702
71pyrimidine nucleobase catabolic process (GO:0006208)3.28762650
72neuromuscular process controlling balance (GO:0050885)3.26630835
73regulation of neurotransmitter uptake (GO:0051580)3.25937887
74cellular sodium ion homeostasis (GO:0006883)3.25653690
75* positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.24502249
76* regulation of synaptic plasticity (GO:0048167)3.23902158
77* regulation of synaptic transmission, glutamatergic (GO:0051966)3.22204563
78acidic amino acid transport (GO:0015800)3.21616897
79positive regulation of potassium ion transmembrane transport (GO:1901381)3.20647164
80G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.19252042
81gamma-aminobutyric acid signaling pathway (GO:0007214)3.18158809
82regulation of dendritic spine morphogenesis (GO:0061001)3.17754232
83glycine transport (GO:0015816)3.17708811
84regulation of postsynaptic membrane potential (GO:0060078)3.16861492
85regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.16473842
86potassium ion homeostasis (GO:0055075)3.15901082
87axonal fasciculation (GO:0007413)3.14931209
88* response to auditory stimulus (GO:0010996)3.13019867
89synaptic vesicle endocytosis (GO:0048488)3.12904757
90regulation of penile erection (GO:0060405)3.12354314
91presynaptic membrane assembly (GO:0097105)3.11966067
92mechanosensory behavior (GO:0007638)3.11086725
93cerebellar granule cell differentiation (GO:0021707)3.07865762
94* long-term synaptic potentiation (GO:0060291)3.07713107
95central nervous system projection neuron axonogenesis (GO:0021952)3.03146046
96positive regulation of synapse maturation (GO:0090129)3.02638573
97positive regulation of synapse assembly (GO:0051965)3.02564816
98regulation of beta-amyloid formation (GO:1902003)3.00878399
99regulation of vesicle fusion (GO:0031338)3.00842785
100epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.99697203
101prepulse inhibition (GO:0060134)2.99606466
102innervation (GO:0060384)2.96952304
103cerebellar Purkinje cell differentiation (GO:0021702)2.94483682
104L-glutamate transport (GO:0015813)2.94374727
105synapse assembly (GO:0007416)2.94321372
106C4-dicarboxylate transport (GO:0015740)2.93641853
107membrane repolarization (GO:0086009)2.92816937
108positive regulation of dendritic spine development (GO:0060999)2.92424809
109cellular response to cholesterol (GO:0071397)2.92409202
110neuronal ion channel clustering (GO:0045161)2.91403659
111* regulation of neurotransmitter secretion (GO:0046928)2.89333874
112membrane hyperpolarization (GO:0060081)2.86350756
113membrane depolarization during action potential (GO:0086010)2.85970730
114neuromuscular process controlling posture (GO:0050884)2.84445303
115presynaptic membrane organization (GO:0097090)2.83384897
116response to histamine (GO:0034776)2.83216020
117photoreceptor cell differentiation (GO:0046530)2.82996875
118eye photoreceptor cell differentiation (GO:0001754)2.82996875
119regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.82891788
120cyclic-nucleotide-mediated signaling (GO:0019935)2.82207864
121nucleobase catabolic process (GO:0046113)2.81676195
122vascular smooth muscle contraction (GO:0014829)2.80995349
123regulation of fever generation (GO:0031620)2.80663127
124* positive regulation of synaptic transmission (GO:0050806)2.79638926
125* regulation of synaptic transmission (GO:0050804)2.78865547
126regulation of respiratory system process (GO:0044065)2.78769454
127* regulation of neurotransmitter transport (GO:0051588)2.78585625
128regulation of dendritic spine development (GO:0060998)2.78131932
129membrane depolarization (GO:0051899)2.77482599
130* learning (GO:0007612)2.77364137
131neuron projection regeneration (GO:0031102)2.76996577
132negative regulation of glial cell differentiation (GO:0045686)2.75870052
133axon regeneration (GO:0031103)2.75216125
134dermatan sulfate biosynthetic process (GO:0030208)2.74132889
135regulation of sensory perception of pain (GO:0051930)2.72040144
136regulation of sensory perception (GO:0051931)2.72040144
137myelination (GO:0042552)2.70862190
138positive regulation of potassium ion transport (GO:0043268)2.70813795

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.73467500
2GBX2_23144817_ChIP-Seq_PC3_Human3.24549908
3* SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.08064410
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.05815491
5* JARID2_20064375_ChIP-Seq_MESCs_Mouse2.96008595
6* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.64645666
7* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.64645666
8* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.61182437
9* REST_21632747_ChIP-Seq_MESCs_Mouse2.58170325
10* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.56174620
11* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.55469658
12* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.54124538
13DROSHA_22980978_ChIP-Seq_HELA_Human2.51926146
14* SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.50633409
15* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.48499822
16* EZH2_27304074_Chip-Seq_ESCs_Mouse2.38761453
17RARB_27405468_Chip-Seq_BRAIN_Mouse2.34533360
18* EED_16625203_ChIP-ChIP_MESCs_Mouse2.32927433
19SUZ12_27294783_Chip-Seq_ESCs_Mouse2.19716775
20* RNF2_27304074_Chip-Seq_ESCs_Mouse2.19016634
21AR_21572438_ChIP-Seq_LNCaP_Human2.19012027
22* EZH2_27294783_Chip-Seq_ESCs_Mouse2.18583194
23* REST_18959480_ChIP-ChIP_MESCs_Mouse2.05135267
24IKZF1_21737484_ChIP-ChIP_HCT116_Human2.01495856
25ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.94354386
26MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.90889400
27GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.90686078
28CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.83154322
29NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.74178207
30EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.72779845
31CTBP2_25329375_ChIP-Seq_LNCAP_Human1.69564678
32CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.59112032
33SMAD4_21799915_ChIP-Seq_A2780_Human1.57143569
34CTBP1_25329375_ChIP-Seq_LNCAP_Human1.52887953
35SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.52556931
36EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.52422432
37* ERG_21242973_ChIP-ChIP_JURKAT_Human1.49090468
38RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.42886275
39PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.40707359
40RING1B_27294783_Chip-Seq_ESCs_Mouse1.40182741
41RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.38765031
42SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.32503303
43SMAD_19615063_ChIP-ChIP_OVARY_Human1.31885778
44* PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.30751248
45P300_19829295_ChIP-Seq_ESCs_Human1.28877045
46* SOX2_21211035_ChIP-Seq_LN229_Gbm1.28281541
47NR3C1_23031785_ChIP-Seq_PC12_Mouse1.27754960
48CBX2_27304074_Chip-Seq_ESCs_Mouse1.27477950
49CDX2_19796622_ChIP-Seq_MESCs_Mouse1.27406791
50PIAS1_25552417_ChIP-Seq_VCAP_Human1.26881546
51SMAD3_21741376_ChIP-Seq_EPCs_Human1.26596141
52* AR_25329375_ChIP-Seq_VCAP_Human1.23791226
53* AR_19668381_ChIP-Seq_PC3_Human1.23750317
54ZFP57_27257070_Chip-Seq_ESCs_Mouse1.23192108
55* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.22203419
56TAF15_26573619_Chip-Seq_HEK293_Human1.21565498
57STAT3_23295773_ChIP-Seq_U87_Human1.21256017
58KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.19876183
59ZNF274_21170338_ChIP-Seq_K562_Hela1.18843759
60POU3F2_20337985_ChIP-ChIP_501MEL_Human1.18478864
61GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18450444
62* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.17696726
63* SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.16390807
64OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.16152743
65* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.15984253
66OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.15041230
67TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.13960100
68* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.12487832
69LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12419301
70RING1B_27294783_Chip-Seq_NPCs_Mouse1.12014487
71TRIM28_21343339_ChIP-Seq_HEK293_Human1.10915261
72STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.09830202
73TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.09058907
74* DNAJC2_21179169_ChIP-ChIP_NT2_Human1.08129110
75EP300_21415370_ChIP-Seq_HL-1_Mouse1.07184152
76* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.06761655
77WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.06659318
78MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.06171005
79* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.06020442
80* YAP1_20516196_ChIP-Seq_MESCs_Mouse1.05955530
81RBPJ_22232070_ChIP-Seq_NCS_Mouse1.05170442
82* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.05049446
83AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.04859899
84* NR3C1_21868756_ChIP-Seq_MCF10A_Human1.04651345
85RXR_22108803_ChIP-Seq_LS180_Human1.03440224
86NANOG_18555785_Chip-Seq_ESCs_Mouse1.02955241
87ARNT_22903824_ChIP-Seq_MCF-7_Human1.02579479
88TCF4_23295773_ChIP-Seq_U87_Human1.02575616
89MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.01541054
90NRF2_20460467_ChIP-Seq_MEFs_Mouse1.00800218
91NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.00800218
92P53_22127205_ChIP-Seq_FIBROBLAST_Human1.00788327
93* SOX9_26525672_Chip-Seq_HEART_Mouse1.00293960
94KDM2B_26808549_Chip-Seq_K562_Human1.00020900
95* TBX3_20139965_ChIP-Seq_MESCs_Mouse0.98942434
96SMAD3_21741376_ChIP-Seq_ESCs_Human0.98278793
97THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.97327794
98AHR_22903824_ChIP-Seq_MCF-7_Human0.96800385
99TP53_16413492_ChIP-PET_HCT116_Human0.96373863
100ZFP281_18757296_ChIP-ChIP_E14_Mouse0.96025373
101* TBX3_20139965_ChIP-Seq_ESCs_Mouse0.95951045
102* SMAD4_21741376_ChIP-Seq_HESCs_Human0.95817268
103EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.95794192
104BCAT_22108803_ChIP-Seq_LS180_Human0.94352216
105CTNNB1_20460455_ChIP-Seq_HCT116_Human0.94069676
106TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.93699903
107ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.93601455
108CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.93493707
109* RUNX2_22187159_ChIP-Seq_PCA_Human0.93380690
110KDM2B_26808549_Chip-Seq_REH_Human0.92870447
111SMAD3_21741376_ChIP-Seq_HESCs_Human0.92507357
112GATA1_26923725_Chip-Seq_HPCs_Mouse0.90824887
113TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89992604
114VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.89652247
115CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89215230
116TAL1_26923725_Chip-Seq_HPCs_Mouse0.88886647
117* BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.88181134
118UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.88011945
119PRDM14_20953172_ChIP-Seq_ESCs_Human0.87767654
120TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.86730496
121TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.85936469
122POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.85936469
123TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.85441033
124RNF2_27304074_Chip-Seq_NSC_Mouse0.84546023
125* TP53_18474530_ChIP-ChIP_U2OS_Human0.84310788
126ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.84138299
127IGF1R_20145208_ChIP-Seq_DFB_Human0.83663508

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1* MP0004859_abnormal_synaptic_plasticity5.85531167
2MP0003136_yellow_coat_color5.79584362
3MP0003880_abnormal_central_pattern4.10716766
4* MP0003635_abnormal_synaptic_transmissio4.03854970
5MP0004270_analgesia3.56528054
6MP0009745_abnormal_behavioral_response3.33920963
7* MP0002063_abnormal_learning/memory/cond3.21751264
8MP0009046_muscle_twitch3.09343926
9* MP0002064_seizures3.08913208
10MP0005423_abnormal_somatic_nervous3.02137394
11MP0001486_abnormal_startle_reflex2.80068344
12* MP0002572_abnormal_emotion/affect_behav2.71512192
13MP0001968_abnormal_touch/_nociception2.68745923
14MP0002734_abnormal_mechanical_nocicepti2.58308634
15MP0003329_amyloid_beta_deposits2.48651529
16MP0002272_abnormal_nervous_system2.47344849
17MP0009780_abnormal_chondrocyte_physiolo2.42965937
18MP0001501_abnormal_sleep_pattern2.30060228
19MP0005646_abnormal_pituitary_gland2.25820035
20MP0001440_abnormal_grooming_behavior2.18747410
21MP0002822_catalepsy2.15426586
22MP0002909_abnormal_adrenal_gland2.11962023
23MP0004885_abnormal_endolymph2.09571584
24MP0008569_lethality_at_weaning2.08974021
25MP0002733_abnormal_thermal_nociception2.04689684
26MP0002736_abnormal_nociception_after2.01712288
27MP0003690_abnormal_glial_cell2.00244208
28MP0000778_abnormal_nervous_system1.92650916
29MP0001970_abnormal_pain_threshold1.89751254
30MP0005645_abnormal_hypothalamus_physiol1.88938167
31MP0002557_abnormal_social/conspecific_i1.86699646
32* MP0002067_abnormal_sensory_capabilities1.86391503
33MP0002735_abnormal_chemical_nociception1.77568186
34MP0001984_abnormal_olfaction1.75751091
35MP0004924_abnormal_behavior1.63167271
36MP0005386_behavior/neurological_phenoty1.63167271
37MP0003633_abnormal_nervous_system1.59082172
38MP0001502_abnormal_circadian_rhythm1.56608079
39* MP0004811_abnormal_neuron_physiology1.55202674
40* MP0000955_abnormal_spinal_cord1.51868994
41* MP0002184_abnormal_innervation1.47172257
42* MP0004858_abnormal_nervous_system1.46911438
43* MP0000026_abnormal_inner_ear1.46012240
44* MP0002882_abnormal_neuron_morphology1.43026933
45MP0005248_abnormal_Harderian_gland1.39832567
46* MP0002066_abnormal_motor_capabilities/c1.38475124
47MP0003631_nervous_system_phenotype1.35227051
48MP0003878_abnormal_ear_physiology1.32951267
49MP0005377_hearing/vestibular/ear_phenot1.32951267
50MP0001958_emphysema1.28187164
51* MP0003634_abnormal_glial_cell1.27177625
52MP0006276_abnormal_autonomic_nervous1.25006439
53MP0000604_amyloidosis1.24155929
54MP0003879_abnormal_hair_cell1.23569504
55MP0005174_abnormal_tail_pigmentation1.23179835
56MP0004142_abnormal_muscle_tone1.21196170
57* MP0002152_abnormal_brain_morphology1.17432870
58MP0003075_altered_response_to1.15071688
59MP0000566_synostosis1.13281695
60MP0003632_abnormal_nervous_system1.12885132
61MP0005167_abnormal_blood-brain_barrier1.12388426
62MP0003787_abnormal_imprinting1.11368573
63MP0001177_atelectasis1.05775775
64MP0000013_abnormal_adipose_tissue1.05378890
65MP0001905_abnormal_dopamine_level1.04354592
66MP0003283_abnormal_digestive_organ1.02789009
67MP0002229_neurodegeneration0.99672846
68MP0001529_abnormal_vocalization0.93772365
69MP0003122_maternal_imprinting0.93502102
70* MP0005551_abnormal_eye_electrophysiolog0.93133726
71MP0001485_abnormal_pinna_reflex0.91296048
72MP0008872_abnormal_physiological_respon0.90958582
73* MP0002069_abnormal_eating/drinking_beha0.90315035
74MP0005535_abnormal_body_temperature0.89708764
75MP0001346_abnormal_lacrimal_gland0.89581092
76MP0000751_myopathy0.88558429
77* MP0000920_abnormal_myelination0.86599689
78MP0000631_abnormal_neuroendocrine_gland0.85271200
79MP0001299_abnormal_eye_distance/0.85006469
80MP0005187_abnormal_penis_morphology0.84096032
81MP0002249_abnormal_larynx_morphology0.84090098
82MP0000569_abnormal_digit_pigmentation0.82565603
83MP0003137_abnormal_impulse_conducting0.81408702
84MP0008961_abnormal_basal_metabolism0.81244318
85MP0004133_heterotaxia0.81039199
86MP0008874_decreased_physiological_sensi0.80559461
87MP0003172_abnormal_lysosome_physiology0.80046298
88MP0004742_abnormal_vestibular_system0.79927120
89MP0002095_abnormal_skin_pigmentation0.79320415
90* MP0001963_abnormal_hearing_physiology0.79206346
91MP0004085_abnormal_heartbeat0.75363970
92MP0005394_taste/olfaction_phenotype0.74989303
93MP0005499_abnormal_olfactory_system0.74989303
94MP0004215_abnormal_myocardial_fiber0.74497495
95MP0001188_hyperpigmentation0.74293417
96MP0004043_abnormal_pH_regulation0.73364039
97MP0005595_abnormal_vascular_smooth0.73281377
98MP0006072_abnormal_retinal_apoptosis0.71676976
99* MP0002752_abnormal_somatic_nervous0.71242844
100MP0004130_abnormal_muscle_cell0.70303615
101MP0004145_abnormal_muscle_electrophysio0.69824290
102MP0003938_abnormal_ear_development0.68264771
103MP0000579_abnormal_nail_morphology0.67103391
104MP0000762_abnormal_tongue_morphology0.65229647
105MP0002653_abnormal_ependyma_morphology0.64360291
106MP0002751_abnormal_autonomic_nervous0.64255314
107MP0005253_abnormal_eye_physiology0.64224665
108MP0002089_abnormal_postnatal_growth/wei0.64207290
109MP0003183_abnormal_peptide_metabolism0.64117071
110MP0010386_abnormal_urinary_bladder0.63804010
111MP0005623_abnormal_meninges_morphology0.63223051
112MP0004233_abnormal_muscle_weight0.62970128
113MP0001664_abnormal_digestion0.62706370
114MP0000534_abnormal_ureter_morphology0.62110195
115* MP0002090_abnormal_vision0.61486287
116MP0000647_abnormal_sebaceous_gland0.61335783
117MP0005379_endocrine/exocrine_gland_phen0.59527826
118MP0001270_distended_abdomen0.58683345
119* MP0010769_abnormal_survival0.58180891
120MP0002928_abnormal_bile_duct0.57786069
121* MP0002638_abnormal_pupillary_reflex0.57534721
122* MP0005195_abnormal_posterior_eye0.56076632
123* MP0010770_preweaning_lethality0.55246818
124* MP0003861_abnormal_nervous_system0.54771368
125* MP0001943_abnormal_respiration0.54090931
126MP0005171_absent_coat_pigmentation0.52300659

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.89911353
2Myokymia (HP:0002411)5.93356835
3Focal seizures (HP:0007359)5.12832747
4Megalencephaly (HP:0001355)4.77735984
5Epileptic encephalopathy (HP:0200134)4.68491416
6Visual hallucinations (HP:0002367)4.57124717
7Split foot (HP:0001839)4.17278646
8Progressive cerebellar ataxia (HP:0002073)4.05544830
9Action tremor (HP:0002345)3.96915645
10Supranuclear gaze palsy (HP:0000605)3.96070915
11Neurofibrillary tangles (HP:0002185)3.95569189
12Generalized tonic-clonic seizures (HP:0002069)3.72321470
13Atonic seizures (HP:0010819)3.71566791
14Absence seizures (HP:0002121)3.67106029
15Febrile seizures (HP:0002373)3.64641331
16Diplopia (HP:0000651)3.49324768
17Abnormality of binocular vision (HP:0011514)3.49324768
18Hemiparesis (HP:0001269)3.47233381
19Cerebral inclusion bodies (HP:0100314)3.39888803
20Dialeptic seizures (HP:0011146)3.36689211
21Dysdiadochokinesis (HP:0002075)3.31172501
22Aplasia involving bones of the extremities (HP:0009825)3.30833729
23Aplasia involving bones of the upper limbs (HP:0009823)3.30833729
24Aplasia of the phalanges of the hand (HP:0009802)3.30833729
25Hemiplegia (HP:0002301)3.24308562
26Depression (HP:0000716)3.18798826
27Coronal craniosynostosis (HP:0004440)3.16883388
28Ankle clonus (HP:0011448)3.12084562
29Postural instability (HP:0002172)3.09480838
30Papilledema (HP:0001085)3.06662662
31Hyperventilation (HP:0002883)3.06481050
32Broad-based gait (HP:0002136)3.03144971
33Truncal ataxia (HP:0002078)3.01856152
34Septo-optic dysplasia (HP:0100842)2.99488178
35Poor eye contact (HP:0000817)2.99450577
36Heterochromia iridis (HP:0001100)2.95878300
37Anxiety (HP:0000739)2.95796611
38Impaired vibration sensation in the lower limbs (HP:0002166)2.81959854
39Dysmetria (HP:0001310)2.81358365
40Abnormal social behavior (HP:0012433)2.81252181
41Impaired social interactions (HP:0000735)2.81252181
42Intention tremor (HP:0002080)2.77930905
43Mutism (HP:0002300)2.77405417
44Gaze-evoked nystagmus (HP:0000640)2.77244318
45Urinary bladder sphincter dysfunction (HP:0002839)2.76328364
46Genetic anticipation (HP:0003743)2.72319271
47Degeneration of the lateral corticospinal tracts (HP:0002314)2.66553951
48Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.66553951
49* Abnormal eating behavior (HP:0100738)2.65996707
50White forelock (HP:0002211)2.64379622
51Drooling (HP:0002307)2.58810687
52Excessive salivation (HP:0003781)2.58810687
53Epileptiform EEG discharges (HP:0011182)2.55379787
54Abnormality of the diencephalon (HP:0010662)2.54405240
55Oligodactyly (hands) (HP:0001180)2.54254404
56Status epilepticus (HP:0002133)2.53556291
57EEG with generalized epileptiform discharges (HP:0011198)2.51863395
58Neonatal short-limb short stature (HP:0008921)2.46463112
59Impaired smooth pursuit (HP:0007772)2.44011866
60Hypsarrhythmia (HP:0002521)2.43481384
61Patchy hypopigmentation of hair (HP:0011365)2.41508137
62Progressive inability to walk (HP:0002505)2.39460623
63Bradykinesia (HP:0002067)2.39291203
64Clumsiness (HP:0002312)2.36732852
65Scanning speech (HP:0002168)2.34895202
66Torticollis (HP:0000473)2.31740821
67Stereotypic behavior (HP:0000733)2.30402213
68Spastic gait (HP:0002064)2.28587757
69Large for gestational age (HP:0001520)2.26342600
70Hammertoe (HP:0001765)2.26166771
71Lower limb muscle weakness (HP:0007340)2.25043090
72True hermaphroditism (HP:0010459)2.24907824
73Urinary urgency (HP:0000012)2.24268500
74Abnormality of ocular smooth pursuit (HP:0000617)2.21580138
75Alacrima (HP:0000522)2.20615513
76Turricephaly (HP:0000262)2.16647883
77Focal dystonia (HP:0004373)2.15612224
78Amblyopia (HP:0000646)2.14371483
79Ulnar claw (HP:0001178)2.13685381
80Insomnia (HP:0100785)2.12754141
81Abnormal auditory evoked potentials (HP:0006958)2.12056373
82Hepatoblastoma (HP:0002884)2.09547335
83Pheochromocytoma (HP:0002666)2.09240928
84Agitation (HP:0000713)2.08495727
85Obstructive sleep apnea (HP:0002870)2.06861456
86Cutaneous finger syndactyly (HP:0010554)2.04781832
87Neuronal loss in central nervous system (HP:0002529)2.03903714
88Generalized myoclonic seizures (HP:0002123)2.02442123
89Oligodactyly (HP:0012165)2.00582729
90Impaired vibratory sensation (HP:0002495)2.00247959
91Optic nerve hypoplasia (HP:0000609)1.96465454
92Gait ataxia (HP:0002066)1.94802119
93Wide anterior fontanel (HP:0000260)1.94770395
94Termporal pattern (HP:0011008)1.94182731
95Insidious onset (HP:0003587)1.94182731
96Ventricular fibrillation (HP:0001663)1.93968739
97Absent speech (HP:0001344)1.92123104
98Limb dystonia (HP:0002451)1.91566244
99Blue irides (HP:0000635)1.91290602
100Bronchomalacia (HP:0002780)1.89291311
101Fibular hypoplasia (HP:0003038)1.88489060
102Rigidity (HP:0002063)1.88487469
103Esophageal atresia (HP:0002032)1.86764868
104Broad foot (HP:0001769)1.86092711
105Psychosis (HP:0000709)1.85819348
106Specific learning disability (HP:0001328)1.85177976
107Inability to walk (HP:0002540)1.84561786
108Craniofacial dystonia (HP:0012179)1.84368743
109Abnormality of the lower motor neuron (HP:0002366)1.84184268
110Aplasia/Hypoplasia of the fibula (HP:0006492)1.84011608
111Hypoplasia of the corpus callosum (HP:0002079)1.83298731
112Abnormality of the 4th metacarpal (HP:0010012)1.82864792
113Fetal akinesia sequence (HP:0001989)1.82549179
114Abnormality of the ischium (HP:0003174)1.82344654
115Morphological abnormality of the pyramidal tract (HP:0002062)1.81608722
116Increased circulating renin level (HP:0000848)1.81431789
117Abnormality of the corticospinal tract (HP:0002492)1.80602366
118Steppage gait (HP:0003376)1.80369664
119Abnormality of saccadic eye movements (HP:0000570)1.78408096
120Cutaneous syndactyly (HP:0012725)1.78237205
121Tetraplegia (HP:0002445)1.77471505
122Clonus (HP:0002169)1.77255740
123Abnormality of salivation (HP:0100755)1.76821693
124Partial duplication of thumb phalanx (HP:0009944)1.75701459
125Abnormal ciliary motility (HP:0012262)1.75525029
126Vertebral arch anomaly (HP:0008438)1.75405614
127Neuroendocrine neoplasm (HP:0100634)1.74469445
128Peripheral hypomyelination (HP:0007182)1.73818935
129Congenital primary aphakia (HP:0007707)1.73069063
130Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.72370477
131Dysmetric saccades (HP:0000641)1.72197157
132Decreased lacrimation (HP:0000633)1.72160855
133Annular pancreas (HP:0001734)1.71956324
134Cortical dysplasia (HP:0002539)1.71227475
135Anophthalmia (HP:0000528)1.71124708
136Morphological abnormality of the inner ear (HP:0011390)1.71039606
137Abnormal respiratory motile cilium physiology (HP:0012261)1.70827096
138Gait imbalance (HP:0002141)1.70687786
139Thickened helices (HP:0000391)1.70196974
140Aqueductal stenosis (HP:0002410)1.69679884
141Pointed chin (HP:0000307)1.69290057
142Genital tract atresia (HP:0001827)1.68284349
143Postural tremor (HP:0002174)1.68227187
144Amyotrophic lateral sclerosis (HP:0007354)1.67763833
145Sleep apnea (HP:0010535)1.67748358
146Vaginal atresia (HP:0000148)1.65477829

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA44.28089783
2NTRK34.10833448
3MAP3K93.51333822
4MARK13.51111243
5MAP3K42.78686471
6PRKD32.66145275
7MAPK152.63174878
8MINK12.51465412
9MAP2K72.34641114
10LMTK22.32713388
11TNIK2.27927764
12PAK62.23587394
13EPHA32.23414049
14PHKG22.08083085
15PHKG12.08083085
16DAPK22.07182141
17NTRK11.96082479
18* NTRK21.86824467
19CASK1.83027514
20KSR21.81664586
21CAMKK11.77317993
22MOS1.65772908
23MAP2K41.63364424
24* CDK51.49724168
25BCR1.46853113
26MAPK131.42638289
27RIPK41.35621760
28KSR11.34035845
29STK381.28047119
30SGK4941.26947481
31SGK2231.26947481
32PRKCG1.25611841
33SGK21.21772559
34STK391.21318239
35TYRO31.20057176
36EPHB21.18636927
37PNCK1.18441395
38SIK21.18095621
39PLK21.15490016
40EPHB11.15189695
41MAP3K121.12015625
42PRPF4B1.09561464
43FES1.08805029
44MAP3K21.06279334
45SGK31.05199223
46PKN11.03823693
47GRK51.03204865
48UHMK11.01500132
49PRKCH1.00955591
50TSSK61.00916526
51CAMKK21.00760414
52DAPK11.00093334
53CAMK2A0.93960091
54WNK40.91873870
55PINK10.90347647
56MAP3K130.90308003
57PAK30.89567031
58LATS20.88351116
59RET0.83447345
60CDK150.83380826
61CAMK10.83051804
62CDK180.82613880
63ARAF0.82521230
64DYRK20.82319025
65CAMK1G0.82294636
66STK110.82120714
67CDK190.81067890
68CDK140.80616573
69CDK30.79810318
70CSNK1A1L0.78783530
71SGK10.78172614
72DYRK1A0.75452361
73CSNK1G30.75215578
74CAMK2B0.72863317
75MARK20.71253426
76CDK11A0.70834246
77ALK0.66254436
78TAOK10.66216063
79CSNK1G10.65216234
80CDC42BPA0.65000309
81CSNK1G20.63968515
82PRKCE0.63691400
83NEK60.62774915
84ERBB20.61863893
85FGFR20.60266378
86MUSK0.58987784
87FGR0.58891258
88NEK90.57353391
89RPS6KA30.55786607
90SCYL20.54604883
91PRKCZ0.54000621
92RAF10.53598542
93ROCK20.52997366
94PAK20.51306763
95TRIB30.50737717
96DMPK0.50370239
97PDPK10.50164027
98CAMK2G0.49871747
99PDK10.49297307
100BCKDK0.48853276
101ERBB30.48533218
102FYN0.48205131
103CAMK2D0.48006773
104TNK20.47911144
105MAPK100.47274720
106OXSR10.47048717
107BMPR1B0.46717363
108MAP3K10.46091050
109WNK10.45608080
110MAPK120.45502489
111ROCK10.44695302
112BMPR20.43108922
113YES10.43046093
114PDGFRB0.41908958
115RIPK10.41192367
116PTK2B0.39720153
117SIK10.37500968
118PDGFRA0.37293687
119WNK30.36772890
120WEE10.36749754
121FER0.36039796
122ICK0.35935136
123MAP3K70.35251602
124PRKG10.34645234
125MET0.34595552
126MAP2K10.34534493
127PRKCA0.33312790
128FGFR10.29911076
129BMX0.28715580

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.49927976
2Nitrogen metabolism_Homo sapiens_hsa009102.96014368
3GABAergic synapse_Homo sapiens_hsa047272.83396234
4Synaptic vesicle cycle_Homo sapiens_hsa047212.78852220
5Glutamatergic synapse_Homo sapiens_hsa047242.55107883
6Circadian entrainment_Homo sapiens_hsa047132.52839777
7Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.45581204
8Olfactory transduction_Homo sapiens_hsa047402.40566297
9Morphine addiction_Homo sapiens_hsa050322.38667504
10Long-term potentiation_Homo sapiens_hsa047202.28960367
11Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.20429645
12Salivary secretion_Homo sapiens_hsa049702.17003305
13Insulin secretion_Homo sapiens_hsa049112.15152800
14Amphetamine addiction_Homo sapiens_hsa050312.12219500
15Gastric acid secretion_Homo sapiens_hsa049711.96935705
16Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.93271469
17Dopaminergic synapse_Homo sapiens_hsa047281.90480596
18Cholinergic synapse_Homo sapiens_hsa047251.72632523
19Aldosterone synthesis and secretion_Homo sapiens_hsa049251.65107043
20Cocaine addiction_Homo sapiens_hsa050301.63055379
21Renin secretion_Homo sapiens_hsa049241.62799064
22Taste transduction_Homo sapiens_hsa047421.60010080
23Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.57422067
24Long-term depression_Homo sapiens_hsa047301.49934244
25Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.48145660
26Serotonergic synapse_Homo sapiens_hsa047261.45883735
27Calcium signaling pathway_Homo sapiens_hsa040201.44764368
28Oxytocin signaling pathway_Homo sapiens_hsa049211.40688743
29Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.40461268
30cAMP signaling pathway_Homo sapiens_hsa040241.30654092
31GnRH signaling pathway_Homo sapiens_hsa049121.26598037
32Gap junction_Homo sapiens_hsa045401.25267993
33Fatty acid biosynthesis_Homo sapiens_hsa000611.24089153
34Vitamin B6 metabolism_Homo sapiens_hsa007501.19248178
35Type II diabetes mellitus_Homo sapiens_hsa049301.15023481
36Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.14017724
37Estrogen signaling pathway_Homo sapiens_hsa049151.09196225
38Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.07453229
39Melanogenesis_Homo sapiens_hsa049161.04641671
40Hippo signaling pathway_Homo sapiens_hsa043901.04174616
41Axon guidance_Homo sapiens_hsa043601.03948795
42Steroid biosynthesis_Homo sapiens_hsa001001.03774190
43Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.00404146
44Glioma_Homo sapiens_hsa052140.99035941
45Dorso-ventral axis formation_Homo sapiens_hsa043200.98822719
46cGMP-PKG signaling pathway_Homo sapiens_hsa040220.96433352
47Phosphatidylinositol signaling system_Homo sapiens_hsa040700.95184235
48Collecting duct acid secretion_Homo sapiens_hsa049660.94540369
49Pancreatic secretion_Homo sapiens_hsa049720.93920716
50Notch signaling pathway_Homo sapiens_hsa043300.93686979
51Basal cell carcinoma_Homo sapiens_hsa052170.92684352
52Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.91886398
53Phospholipase D signaling pathway_Homo sapiens_hsa040720.89156460
54Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.87849990
55ErbB signaling pathway_Homo sapiens_hsa040120.87473432
56Carbohydrate digestion and absorption_Homo sapiens_hsa049730.86497107
57Thyroid hormone synthesis_Homo sapiens_hsa049180.86458049
58Bile secretion_Homo sapiens_hsa049760.84908478
59Type I diabetes mellitus_Homo sapiens_hsa049400.82455217
60Hedgehog signaling pathway_Homo sapiens_hsa043400.79462329
61Vascular smooth muscle contraction_Homo sapiens_hsa042700.79282732
62PPAR signaling pathway_Homo sapiens_hsa033200.78846628
63beta-Alanine metabolism_Homo sapiens_hsa004100.78536289
64Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.78103121
65Cardiac muscle contraction_Homo sapiens_hsa042600.78057543
66Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.75788079
67Circadian rhythm_Homo sapiens_hsa047100.75022312
68Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.74883262
69Propanoate metabolism_Homo sapiens_hsa006400.73844705
70Dilated cardiomyopathy_Homo sapiens_hsa054140.70348359
71Choline metabolism in cancer_Homo sapiens_hsa052310.68878398
72Arginine and proline metabolism_Homo sapiens_hsa003300.67194092
73Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.65162614
74Thyroid hormone signaling pathway_Homo sapiens_hsa049190.65115938
75Glucagon signaling pathway_Homo sapiens_hsa049220.63884361
76Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.63304634
77Butanoate metabolism_Homo sapiens_hsa006500.62878804
78Vibrio cholerae infection_Homo sapiens_hsa051100.61944091
79Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.61798346
80Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.59953942
81Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.59850237
82Sphingolipid signaling pathway_Homo sapiens_hsa040710.59511718
83Oocyte meiosis_Homo sapiens_hsa041140.58772126
84Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.56045816
85Tight junction_Homo sapiens_hsa045300.54598683
86Histidine metabolism_Homo sapiens_hsa003400.54250750
87* MAPK signaling pathway_Homo sapiens_hsa040100.54138356
88Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.54076828
89Ras signaling pathway_Homo sapiens_hsa040140.51938804
90Rap1 signaling pathway_Homo sapiens_hsa040150.51838539
91Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.51777219
92Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.49223815
93Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.48959136
94Colorectal cancer_Homo sapiens_hsa052100.47038203
95Prion diseases_Homo sapiens_hsa050200.47001950
96Adherens junction_Homo sapiens_hsa045200.45489754
97* Neurotrophin signaling pathway_Homo sapiens_hsa047220.44365682
98Insulin signaling pathway_Homo sapiens_hsa049100.43871341
99Renal cell carcinoma_Homo sapiens_hsa052110.41090909
100Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.40860882
101Wnt signaling pathway_Homo sapiens_hsa043100.40812860
102Phototransduction_Homo sapiens_hsa047440.40583415
103Endometrial cancer_Homo sapiens_hsa052130.39632248
104Longevity regulating pathway - mammal_Homo sapiens_hsa042110.39320767
105Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.39280786
106Glycerophospholipid metabolism_Homo sapiens_hsa005640.39160435
107mTOR signaling pathway_Homo sapiens_hsa041500.38962166
108Ovarian steroidogenesis_Homo sapiens_hsa049130.38392593
109VEGF signaling pathway_Homo sapiens_hsa043700.38067819
110Mineral absorption_Homo sapiens_hsa049780.37532954
111Endocytosis_Homo sapiens_hsa041440.37527867
112Inositol phosphate metabolism_Homo sapiens_hsa005620.35918583
113Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.35874926
114* Alcoholism_Homo sapiens_hsa050340.31974195
115Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.31207896
116Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.31082827
117Adipocytokine signaling pathway_Homo sapiens_hsa049200.29646864
118Fatty acid metabolism_Homo sapiens_hsa012120.29549593
119African trypanosomiasis_Homo sapiens_hsa051430.28970714
120Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.26232783

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