NUBP2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes an adenosine triphosphate (ATP) and metal-binding protein that is required for the assembly of cyotosolic iron-sulfur proteins. The encoded protein functions in a heterotetramer with nucleotide-binding protein 1 (NUBP1). Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)5.69278531
2base-excision repair, AP site formation (GO:0006285)4.99462157
3DNA strand elongation involved in DNA replication (GO:0006271)4.79887307
4proteasome assembly (GO:0043248)4.73405306
5telomere maintenance via semi-conservative replication (GO:0032201)4.73390321
6GDP-mannose metabolic process (GO:0019673)4.65763410
7pyrimidine deoxyribonucleotide catabolic process (GO:0009223)4.65335605
8ribosomal small subunit assembly (GO:0000028)4.61792636
9DNA strand elongation (GO:0022616)4.58218347
10regulation of mitochondrial translation (GO:0070129)4.56876474
11guanosine-containing compound biosynthetic process (GO:1901070)4.37561198
12UTP biosynthetic process (GO:0006228)4.27144330
13pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)4.26664080
14DNA replication initiation (GO:0006270)4.26500183
15nucleobase biosynthetic process (GO:0046112)4.25734783
16formation of translation preinitiation complex (GO:0001731)4.21154520
17* iron-sulfur cluster assembly (GO:0016226)4.18913002
18* metallo-sulfur cluster assembly (GO:0031163)4.18913002
19maturation of SSU-rRNA (GO:0030490)4.17727943
20GTP biosynthetic process (GO:0006183)4.17527541
21purine nucleobase biosynthetic process (GO:0009113)4.17427422
22peptidyl-arginine omega-N-methylation (GO:0035247)4.15259858
23telomere maintenance via recombination (GO:0000722)4.14028171
24pyrimidine nucleoside triphosphate metabolic process (GO:0009147)4.13876508
25negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.04898140
26pyrimidine nucleotide catabolic process (GO:0006244)4.01466791
27DNA replication checkpoint (GO:0000076)4.00058149
28pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.98959433
29chaperone-mediated protein transport (GO:0072321)3.94655748
30UTP metabolic process (GO:0046051)3.91257842
31CTP biosynthetic process (GO:0006241)3.90513176
32CTP metabolic process (GO:0046036)3.90513176
33deoxyribonucleotide catabolic process (GO:0009264)3.89803227
34protein maturation by protein folding (GO:0022417)3.83975548
35pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.83899831
36ribosomal small subunit biogenesis (GO:0042274)3.82123450
37nuclear envelope reassembly (GO:0031468)3.81519268
38mitotic nuclear envelope reassembly (GO:0007084)3.81519268
39regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.80833017
40L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.79805109
41purine deoxyribonucleotide catabolic process (GO:0009155)3.79532108
42protein targeting to mitochondrion (GO:0006626)3.79503778
43termination of RNA polymerase III transcription (GO:0006386)3.79010304
44transcription elongation from RNA polymerase III promoter (GO:0006385)3.79010304
45positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.78974267
46ribosome biogenesis (GO:0042254)3.78879639
47anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.78451198
48negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.74225999
49negative regulation of ligase activity (GO:0051352)3.74225999
50viral transcription (GO:0019083)3.74156950
51pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)3.74000173
52mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.72754062
53pseudouridine synthesis (GO:0001522)3.71479168
54ribonucleoprotein complex biogenesis (GO:0022613)3.69359059
55mitotic recombination (GO:0006312)3.67972368
56translational termination (GO:0006415)3.66688212
57DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.66540821
58histone arginine methylation (GO:0034969)3.65890448
59deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.65778284
60regulation of cellular amino acid metabolic process (GO:0006521)3.63050370
61energy coupled proton transport, down electrochemical gradient (GO:0015985)3.62849739
62ATP synthesis coupled proton transport (GO:0015986)3.62849739
63protein complex biogenesis (GO:0070271)3.61747335
64signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.60726783
65intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.60726783
66deoxyribose phosphate catabolic process (GO:0046386)3.60566320
67peptidyl-histidine modification (GO:0018202)3.60259022
68telomere maintenance via telomere lengthening (GO:0010833)3.59861293
69establishment of protein localization to mitochondrion (GO:0072655)3.59676424
70signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.59589603
71signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.59589603
72signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.59589603
73rRNA modification (GO:0000154)3.58998234
74antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.54473691
75rRNA processing (GO:0006364)3.53867048
76mitochondrial respiratory chain complex I assembly (GO:0032981)3.53633164
77NADH dehydrogenase complex assembly (GO:0010257)3.53633164
78mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.53633164
79ribosomal large subunit biogenesis (GO:0042273)3.50449480
80signal transduction involved in DNA integrity checkpoint (GO:0072401)3.50447860
81signal transduction involved in DNA damage checkpoint (GO:0072422)3.50447860
82protein insertion into membrane (GO:0051205)3.49151776
83ribosome assembly (GO:0042255)3.46562078
84nucleotide-excision repair, DNA gap filling (GO:0006297)3.46177930
85signal transduction involved in cell cycle checkpoint (GO:0072395)3.45708500
86establishment of protein localization to mitochondrial membrane (GO:0090151)3.43260647
877-methylguanosine mRNA capping (GO:0006370)3.42961122
88mitochondrial respiratory chain complex assembly (GO:0033108)3.42842597
89translational elongation (GO:0006414)3.42770583
90SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.40188104
91rRNA metabolic process (GO:0016072)3.39917468
92translational initiation (GO:0006413)3.39896496
93transcription-coupled nucleotide-excision repair (GO:0006283)3.36487829
947-methylguanosine RNA capping (GO:0009452)3.36254872
95RNA capping (GO:0036260)3.36254872
962-deoxyribonucleotide metabolic process (GO:0009394)3.35549228
97antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.35374702
98spliceosomal snRNP assembly (GO:0000387)3.35096214
99CENP-A containing nucleosome assembly (GO:0034080)3.34863068
100cotranslational protein targeting to membrane (GO:0006613)3.34624815
101peptidyl-arginine N-methylation (GO:0035246)3.33263506
102peptidyl-arginine methylation (GO:0018216)3.33263506
103L-methionine salvage (GO:0071267)3.33262636
104L-methionine biosynthetic process (GO:0071265)3.33262636
105amino acid salvage (GO:0043102)3.33262636
106protein targeting to ER (GO:0045047)3.32823361
107negative regulation of B cell apoptotic process (GO:0002903)3.31481461
108mitotic metaphase plate congression (GO:0007080)3.30256293
109deoxyribose phosphate biosynthetic process (GO:0046385)3.29819775
1102-deoxyribonucleotide biosynthetic process (GO:0009265)3.29819775
111regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.29055186
112negative regulation of DNA-templated transcription, elongation (GO:0032785)3.28425666
113G1/S transition of mitotic cell cycle (GO:0000082)3.28155167
114cell cycle G1/S phase transition (GO:0044843)3.28155167
115positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.28103428
116negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.27011785
117protein localization to mitochondrion (GO:0070585)3.26408574
118tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.24609371
119RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.24609371
120GMP metabolic process (GO:0046037)3.24350797
121translation (GO:0006412)3.23405394
122chromatin remodeling at centromere (GO:0031055)3.23369629
123mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.22584254
124protein localization to endoplasmic reticulum (GO:0070972)3.22517314
125negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)3.22388998
126deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.20151013
127positive regulation of ligase activity (GO:0051351)3.19895569
128negative regulation of cell size (GO:0045792)3.18581532
129ncRNA 3-end processing (GO:0043628)3.17203752
130proline biosynthetic process (GO:0006561)3.17196111
131oxidative phosphorylation (GO:0006119)3.17063870
132respiratory electron transport chain (GO:0022904)3.17015955
133folic acid metabolic process (GO:0046655)3.14085877
134establishment of protein localization to endoplasmic reticulum (GO:0072599)3.14064059
135electron transport chain (GO:0022900)3.13703413
136rRNA transcription (GO:0009303)3.12239750
137IMP biosynthetic process (GO:0006188)3.11179249
138nucleobase-containing small molecule interconversion (GO:0015949)3.11160334
139DNA unwinding involved in DNA replication (GO:0006268)3.10540430
140base-excision repair (GO:0006284)3.08807678
141tRNA modification (GO:0006400)3.08628652
142cellular component biogenesis (GO:0044085)3.07878977
143viral mRNA export from host cell nucleus (GO:0046784)3.06855320
144maturation of 5.8S rRNA (GO:0000460)3.06367520
145deoxyribose phosphate metabolic process (GO:0019692)3.04619803
146exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.04424687
147DNA replication-dependent nucleosome assembly (GO:0006335)3.04286745
148DNA replication-dependent nucleosome organization (GO:0034723)3.04286745
149pentose metabolic process (GO:0019321)3.01420010
150protein deneddylation (GO:0000338)3.01015824
151nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.00734379
152folic acid-containing compound biosynthetic process (GO:0009396)2.99939895
153tRNA methylation (GO:0030488)2.99392216
154regulation of ubiquitin-protein transferase activity (GO:0051438)2.99013836
155cullin deneddylation (GO:0010388)2.98177520
156respiratory chain complex IV assembly (GO:0008535)2.97522741
157activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO2.97408899
158DNA damage response, signal transduction by p53 class mediator (GO:0030330)2.96789681
159purine deoxyribonucleotide metabolic process (GO:0009151)2.96264364
160nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.95224461
161cytochrome complex assembly (GO:0017004)2.95178635
162regulation of ligase activity (GO:0051340)2.93417050
163DNA replication-independent nucleosome assembly (GO:0006336)2.92858301
164DNA replication-independent nucleosome organization (GO:0034724)2.92858301
165viral life cycle (GO:0019058)2.92267549
166cellular protein complex disassembly (GO:0043624)2.92006240
167transcription from RNA polymerase I promoter (GO:0006360)2.91430259
168positive regulation of cell cycle arrest (GO:0071158)2.90364713
169regulation of double-strand break repair via homologous recombination (GO:0010569)2.87923028
170transcription elongation from RNA polymerase I promoter (GO:0006362)2.85737195
171termination of RNA polymerase I transcription (GO:0006363)2.85467079
172IMP metabolic process (GO:0046040)2.84999345
173establishment of integrated proviral latency (GO:0075713)2.80262299
174protein localization to kinetochore (GO:0034501)2.78935431

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.42162478
2* MYC_18555785_ChIP-Seq_MESCs_Mouse3.92690440
3* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.84994880
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.76533465
5JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.52506694
6GABP_17652178_ChIP-ChIP_JURKAT_Human3.44967554
7EST1_17652178_ChIP-ChIP_JURKAT_Human3.44071620
8TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.25220378
9ETS1_20019798_ChIP-Seq_JURKAT_Human3.21364417
10NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.15625297
11* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.98631528
12CREB1_15753290_ChIP-ChIP_HEK293T_Human2.98430820
13ELF1_17652178_ChIP-ChIP_JURKAT_Human2.88625196
14E2F4_17652178_ChIP-ChIP_JURKAT_Human2.82814230
15SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.81253345
16* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.68868257
17* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.58824035
18* HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.54881869
19VDR_23849224_ChIP-Seq_CD4+_Human2.48457927
20E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.45005916
21FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.44253940
22CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.43409469
23CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.42952287
24XRN2_22483619_ChIP-Seq_HELA_Human2.28372438
25TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.22135661
26HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.21913650
27FOXM1_23109430_ChIP-Seq_U2OS_Human2.19819770
28* MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.17289691
29* DCP1A_22483619_ChIP-Seq_HELA_Human2.13515552
30NELFA_20434984_ChIP-Seq_ESCs_Mouse2.12035726
31SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.11101990
32* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.09151284
33PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.08833012
34FOXP3_21729870_ChIP-Seq_TREG_Human2.08623749
35GABP_19822575_ChIP-Seq_HepG2_Human2.01103687
36* SRF_21415370_ChIP-Seq_HL-1_Mouse1.93702134
37THAP11_20581084_ChIP-Seq_MESCs_Mouse1.91991315
38YY1_21170310_ChIP-Seq_MESCs_Mouse1.87794188
39* TET1_21451524_ChIP-Seq_MESCs_Mouse1.84233749
40TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.77349082
41LXR_22292898_ChIP-Seq_THP-1_Human1.76197832
42FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.75708881
43* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.75307509
44HOXB4_20404135_ChIP-ChIP_EML_Mouse1.67545430
45POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.67483482
46TTF2_22483619_ChIP-Seq_HELA_Human1.66251850
47P68_20966046_ChIP-Seq_HELA_Human1.65453640
48MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.64978148
49MYCN_18555785_ChIP-Seq_MESCs_Mouse1.64565159
50PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.64219264
51CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.63387501
52NANOG_18555785_ChIP-Seq_MESCs_Mouse1.61857839
53PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.59688150
54ELK1_19687146_ChIP-ChIP_HELA_Human1.57285444
55ZNF263_19887448_ChIP-Seq_K562_Human1.51302540
56ERG_20887958_ChIP-Seq_HPC-7_Mouse1.49827276
57ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.49310155
58SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.48249915
59AR_21909140_ChIP-Seq_LNCAP_Human1.48218197
60* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.48087540
61ELF1_20517297_ChIP-Seq_JURKAT_Human1.46079152
62SRY_22984422_ChIP-ChIP_TESTIS_Rat1.44782637
63BCL6_27268052_Chip-Seq_Bcells_Human1.42175159
64FOXP1_21924763_ChIP-Seq_HESCs_Human1.41468483
65MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.40115983
66CIITA_25753668_ChIP-Seq_RAJI_Human1.38486106
67* E2F1_21310950_ChIP-Seq_MCF-7_Human1.37796396
68ZFX_18555785_ChIP-Seq_MESCs_Mouse1.35769564
69CTCF_26484167_Chip-Seq_Bcells_Mouse1.33772209
70ELK3_25401928_ChIP-Seq_HUVEC_Human1.33188675
71KDM5A_27292631_Chip-Seq_BREAST_Human1.31824121
72SA1_27219007_Chip-Seq_ERYTHROID_Human1.31375376
73YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.29262481
74* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.28477443
75SPI1_23547873_ChIP-Seq_NB4_Human1.26270701
76PHF8_20622854_ChIP-Seq_HELA_Human1.22977078
77BCOR_27268052_Chip-Seq_Bcells_Human1.22823027
78IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.22054963
79RACK7_27058665_Chip-Seq_MCF-7_Human1.22047620
80MAF_26560356_Chip-Seq_TH2_Human1.20008526
81CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.18363863
82* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.18274459
83ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.17938430
84NOTCH1_21737748_ChIP-Seq_TLL_Human1.16830615
85YY1_22570637_ChIP-Seq_MALME-3M_Human1.16716376
86STAT3_1855785_ChIP-Seq_MESCs_Mouse1.15200715
87ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.15173941
88SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.15148110
89ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.10550806
90KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.09279611
91CTCF_27219007_Chip-Seq_ERYTHROID_Human1.09047840
92E2F1_20622854_ChIP-Seq_HELA_Human1.08781772
93CTCF_21964334_Chip-Seq_Bcells_Human1.08759048
94IRF8_21731497_ChIP-ChIP_J774_Mouse1.08384786
95* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.08164051
96* SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.07264011
97CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.06672654
98KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.06514751
99RARB_24833708_ChIP-Seq_LIVER_Mouse1.06085532
100* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.05815000
101PADI4_21655091_ChIP-ChIP_MCF-7_Human1.05550644
102SMC4_20622854_ChIP-Seq_HELA_Human1.05413385
103SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.04533544
104CTCF_20526341_ChIP-Seq_ESCs_Human1.03523413
105TFEB_21752829_ChIP-Seq_HELA_Human1.03404460
106EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.03206476
107KLF4_18555785_ChIP-Seq_MESCs_Mouse1.03095278
108TBX5_21415370_ChIP-Seq_HL-1_Mouse1.03048296
109BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.02939060
110ELK1_22589737_ChIP-Seq_MCF10A_Human1.02435122
111POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.02225805
112MYC_22102868_ChIP-Seq_BL_Human1.00300438
113POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.99737437
114ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.99723547
115GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.98471722
116RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.97159524
117SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.95071922
118CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.94225850
119MYC_18940864_ChIP-ChIP_HL60_Human0.93365755
120VDR_21846776_ChIP-Seq_THP-1_Human0.93088690
121MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.92927513
122CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.91443361
123DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.89404488
124* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.87753930
125STAT4_19710469_ChIP-ChIP_TH1__Mouse0.86921740
126CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.85430576
127MYB_21317192_ChIP-Seq_ERMYB_Mouse0.83901551
128GATA1_22383799_ChIP-Seq_G1ME_Mouse0.83262889
129HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.81313641
130CTCF_18555785_ChIP-Seq_MESCs_Mouse0.78988402
131KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.78816416
132* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.77336354
133PU.1_20513432_ChIP-Seq_Bcells_Mouse0.77091835
134IRF8_22096565_ChIP-ChIP_GC-B_Human0.74700813
135NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.73274740
136SOX2_18555785_ChIP-Seq_MESCs_Mouse0.72727335
137MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.72608308

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.39620769
2MP0004957_abnormal_blastocyst_morpholog4.01299357
3MP0010094_abnormal_chromosome_stability3.92355078
4MP0008057_abnormal_DNA_replication3.89770396
5MP0003111_abnormal_nucleus_morphology3.88281937
6MP0003077_abnormal_cell_cycle3.51396071
7MP0008058_abnormal_DNA_repair3.29577461
8MP0003806_abnormal_nucleotide_metabolis3.10923264
9MP0002396_abnormal_hematopoietic_system2.81744728
10MP0008007_abnormal_cellular_replicative2.56910028
11MP0010030_abnormal_orbit_morphology2.48030895
12MP0008932_abnormal_embryonic_tissue2.40469056
13MP0000678_abnormal_parathyroid_gland2.33859639
14MP0002249_abnormal_larynx_morphology2.30676599
15MP0008789_abnormal_olfactory_epithelium2.28950416
16MP0003718_maternal_effect2.20497074
17MP0009333_abnormal_splenocyte_physiolog2.14290138
18MP0003186_abnormal_redox_activity2.09570403
19MP0005394_taste/olfaction_phenotype2.09052819
20MP0005499_abnormal_olfactory_system2.09052819
21MP0003786_premature_aging2.08953162
22MP0000749_muscle_degeneration2.06105342
23MP0008877_abnormal_DNA_methylation1.97828330
24MP0005397_hematopoietic_system_phenotyp1.96975907
25MP0001545_abnormal_hematopoietic_system1.96975907
26MP0002653_abnormal_ependyma_morphology1.89096613
27MP0001835_abnormal_antigen_presentation1.87654651
28MP0003656_abnormal_erythrocyte_physiolo1.87332809
29MP0005671_abnormal_response_to1.85999164
30MP0003763_abnormal_thymus_physiology1.82701745
31MP0001661_extended_life_span1.80380174
32MP0000049_abnormal_middle_ear1.77091191
33MP0000490_abnormal_crypts_of1.73686397
34MP0001730_embryonic_growth_arrest1.71102570
35MP0000751_myopathy1.70569485
36MP0009278_abnormal_bone_marrow1.67127830
37MP0002398_abnormal_bone_marrow1.63418037
38MP0009785_altered_susceptibility_to1.63414601
39MP0004147_increased_porphyrin_level1.63135673
40MP0006036_abnormal_mitochondrial_physio1.62338064
41MP0000350_abnormal_cell_proliferation1.62065838
42MP0000689_abnormal_spleen_morphology1.59535051
43MP0000750_abnormal_muscle_regeneration1.54963433
44MP0006292_abnormal_olfactory_placode1.54753435
45MP0002019_abnormal_tumor_incidence1.53265362
46MP0002822_catalepsy1.52021545
47MP0009379_abnormal_foot_pigmentation1.51328051
48MP0002722_abnormal_immune_system1.49133979
49MP0000685_abnormal_immune_system1.48282717
50MP0000681_abnormal_thyroid_gland1.45135699
51MP0005075_abnormal_melanosome_morpholog1.43909536
52MP0008995_early_reproductive_senescence1.43298989
53MP0002736_abnormal_nociception_after1.43234305
54MP0002102_abnormal_ear_morphology1.41460265
55MP0005501_abnormal_skin_physiology1.40539472
56MP0000313_abnormal_cell_death1.40360141
57MP0005025_abnormal_response_to1.38275779
58MP0002429_abnormal_blood_cell1.35764556
59MP0005330_cardiomyopathy1.35351966
60MP0002148_abnormal_hypersensitivity_rea1.34486734
61MP0001800_abnormal_humoral_immune1.33932194
62MP0002132_abnormal_respiratory_system1.33605714
63MP0008260_abnormal_autophagy1.33089832
64MP0002420_abnormal_adaptive_immunity1.32543778
65MP0001853_heart_inflammation1.32319427
66MP0005670_abnormal_white_adipose1.32246536
67MP0000716_abnormal_immune_system1.32167120
68MP0002723_abnormal_immune_serum1.31599412
69MP0006035_abnormal_mitochondrial_morpho1.30740117
70MP0001819_abnormal_immune_cell1.30253565
71MP0001849_ear_inflammation1.29488326
72MP0005410_abnormal_fertilization1.26714294
73MP0000537_abnormal_urethra_morphology1.26192045
74MP0002452_abnormal_antigen_presenting1.26106668
75MP0004858_abnormal_nervous_system1.25339822
76MP0001929_abnormal_gametogenesis1.21257702
77MP0005000_abnormal_immune_tolerance1.20493164
78MP0004808_abnormal_hematopoietic_stem1.20228361
79MP0001764_abnormal_homeostasis1.18402529
80MP0000358_abnormal_cell_content/1.17771748
81MP0002210_abnormal_sex_determination1.15049577
82MP0002080_prenatal_lethality1.14885594
83MP0000703_abnormal_thymus_morphology1.14333370
84MP0005174_abnormal_tail_pigmentation1.13773282
85MP0002163_abnormal_gland_morphology1.13144651
86MP0000858_altered_metastatic_potential1.12255305
87MP0004782_abnormal_surfactant_physiolog1.08518083
88MP0002419_abnormal_innate_immunity1.06792546
89MP0002095_abnormal_skin_pigmentation1.05964563
90MP0003137_abnormal_impulse_conducting1.05456360
91MP0003436_decreased_susceptibility_to1.05398527
92MP0003136_yellow_coat_color1.05185711
93MP0009840_abnormal_foam_cell1.03516489
94MP0001145_abnormal_male_reproductive1.03188414
95MP0000003_abnormal_adipose_tissue1.01660085
96MP0002405_respiratory_system_inflammati1.01434179
97MP0001697_abnormal_embryo_size1.00055923
98MP0000467_abnormal_esophagus_morphology0.99032726
99MP0000465_gastrointestinal_hemorrhage0.96040544
100MP0010307_abnormal_tumor_latency0.95546644
101MP0005464_abnormal_platelet_physiology0.95274294
102MP0001986_abnormal_taste_sensitivity0.94783900
103MP0000759_abnormal_skeletal_muscle0.94162353
104MP0003123_paternal_imprinting0.89498101
105MP0001968_abnormal_touch/_nociception0.86797149
106MP0005387_immune_system_phenotype0.86405808
107MP0001790_abnormal_immune_system0.86405808
108MP0000653_abnormal_sex_gland0.86254331
109MP0002160_abnormal_reproductive_system0.83640485
110MP0003724_increased_susceptibility_to0.82727127
111MP0005083_abnormal_biliary_tract0.82402160
112MP0001672_abnormal_embryogenesis/_devel0.81572698
113MP0005380_embryogenesis_phenotype0.81572698
114MP0001529_abnormal_vocalization0.81280643
115MP0008469_abnormal_protein_level0.81036875
116MP0004133_heterotaxia0.80824193
117MP0001845_abnormal_inflammatory_respons0.80275757
118MP0003866_abnormal_defecation0.79618867
119MP0002234_abnormal_pharynx_morphology0.78701265
120MP0001542_abnormal_bone_strength0.78691947
121MP0001188_hyperpigmentation0.77903562
122MP0004185_abnormal_adipocyte_glucose0.77265392
123MP0002269_muscular_atrophy0.75621871
124MP0001873_stomach_inflammation0.75439798
125MP0001346_abnormal_lacrimal_gland0.75284115
126MP0001727_abnormal_embryo_implantation0.74970130
127MP0001905_abnormal_dopamine_level0.72988012
128MP0001919_abnormal_reproductive_system0.72615361
129MP0005266_abnormal_metabolism0.72239237
130MP0003984_embryonic_growth_retardation0.72135513
131MP0001881_abnormal_mammary_gland0.71906012
132MP0005058_abnormal_lysosome_morphology0.71839917
133MP0005384_cellular_phenotype0.70758046
134MP0000372_irregular_coat_pigmentation0.70254455
135MP0002932_abnormal_joint_morphology0.69699909
136MP0008873_increased_physiological_sensi0.68724605
137MP0002088_abnormal_embryonic_growth/wei0.67992249
138MP0005451_abnormal_body_composition0.67180152
139MP0008872_abnormal_physiological_respon0.67146749
140MP0003698_abnormal_male_reproductive0.67024615
141MP0000015_abnormal_ear_pigmentation0.66684759
142MP0003221_abnormal_cardiomyocyte_apopto0.66575138
143MP0002970_abnormal_white_adipose0.66233126
144MP0000013_abnormal_adipose_tissue0.65953433
145MP0008875_abnormal_xenobiotic_pharmacok0.65673958
146MP0003315_abnormal_perineum_morphology0.65521183
147MP0000747_muscle_weakness0.60434205
148MP0005319_abnormal_enzyme/_coenzyme0.60070192
149MP0005389_reproductive_system_phenotype0.59209448
150MP0005584_abnormal_enzyme/coenzyme_acti0.57489961
151MP0002085_abnormal_embryonic_tissue0.57220721
152MP0004233_abnormal_muscle_weight0.56879773
153MP0008770_decreased_survivor_rate0.56809598
154MP0005377_hearing/vestibular/ear_phenot0.56224950

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.95596680
2Abnormality of cells of the erythroid lineage (HP:0012130)4.72790710
3Abnormal number of erythroid precursors (HP:0012131)4.71563114
4Cerebral hypomyelination (HP:0006808)4.17643330
5Breast hypoplasia (HP:0003187)4.03055691
6Reticulocytopenia (HP:0001896)3.95907732
7Aplastic anemia (HP:0001915)3.84810194
8Oral leukoplakia (HP:0002745)3.64059979
9Testicular atrophy (HP:0000029)3.61140102
10Ragged-red muscle fibers (HP:0003200)3.59670501
11Progressive macrocephaly (HP:0004481)3.57147627
12Hepatocellular necrosis (HP:0001404)3.46352710
13Cerebral edema (HP:0002181)3.37127019
14Rough bone trabeculation (HP:0100670)3.32334758
15Degeneration of anterior horn cells (HP:0002398)3.26217619
16Abnormality of the anterior horn cell (HP:0006802)3.26217619
17Decreased activity of mitochondrial respiratory chain (HP:0008972)3.24147513
18Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.24147513
19Hepatic necrosis (HP:0002605)3.15568169
20Macrocytic anemia (HP:0001972)3.12986690
21Type I transferrin isoform profile (HP:0003642)3.04710037
22Progressive microcephaly (HP:0000253)3.01125377
23Carpal bone hypoplasia (HP:0001498)2.97870654
24Mitochondrial inheritance (HP:0001427)2.97486046
25Broad distal phalanx of finger (HP:0009836)2.97302062
26Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.96937688
27Increased hepatocellular lipid droplets (HP:0006565)2.92336758
28Increased serum lactate (HP:0002151)2.91391692
29Abnormality of the heme biosynthetic pathway (HP:0010472)2.88577114
30Premature graying of hair (HP:0002216)2.85435592
31Increased CSF lactate (HP:0002490)2.83699709
323-Methylglutaconic aciduria (HP:0003535)2.79758011
33Abnormality of glycolysis (HP:0004366)2.76309028
34Increased serum pyruvate (HP:0003542)2.76309028
35Pallor (HP:0000980)2.76150262
36Exertional dyspnea (HP:0002875)2.75710921
37Progressive muscle weakness (HP:0003323)2.73322675
38IgM deficiency (HP:0002850)2.72068627
39Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.69996967
40Opisthotonus (HP:0002179)2.69525718
41Thrombocytosis (HP:0001894)2.66902545
42Stridor (HP:0010307)2.65384397
43Pancytopenia (HP:0001876)2.63157898
44Lipid accumulation in hepatocytes (HP:0006561)2.62417278
45Cerebral palsy (HP:0100021)2.61103083
46CNS hypomyelination (HP:0003429)2.59137569
47Bone marrow hypocellularity (HP:0005528)2.53336226
48Chromsome breakage (HP:0040012)2.52496482
49Patellar aplasia (HP:0006443)2.49690626
50Aplasia/Hypoplasia of the sacrum (HP:0008517)2.48156960
51Myopathic facies (HP:0002058)2.47733382
52Acute necrotizing encephalopathy (HP:0006965)2.46311221
53Hypoplasia of the capital femoral epiphysis (HP:0003090)2.45458433
54Abnormal protein N-linked glycosylation (HP:0012347)2.45282670
55Abnormal protein glycosylation (HP:0012346)2.45282670
56Abnormal glycosylation (HP:0012345)2.45282670
57Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.45282670
58Poor suck (HP:0002033)2.44667513
59Selective tooth agenesis (HP:0001592)2.42067604
60Reduced antithrombin III activity (HP:0001976)2.41171708
61Abnormality of the preputium (HP:0100587)2.39879799
62Microretrognathia (HP:0000308)2.38821859
63Abnormal trabecular bone morphology (HP:0100671)2.38067559
64Multiple enchondromatosis (HP:0005701)2.36083320
65Chromosomal breakage induced by crosslinking agents (HP:0003221)2.35795450
66Aplasia/Hypoplasia of the patella (HP:0006498)2.35736264
67Abnormal mitochondria in muscle tissue (HP:0008316)2.34262489
68Petechiae (HP:0000967)2.33659181
69Dicarboxylic aciduria (HP:0003215)2.31903745
70Abnormality of dicarboxylic acid metabolism (HP:0010995)2.31903745
71CNS demyelination (HP:0007305)2.28111446
72Abnormal spermatogenesis (HP:0008669)2.27843200
73Cellular immunodeficiency (HP:0005374)2.27666459
74Poor head control (HP:0002421)2.27560796
75Renal Fanconi syndrome (HP:0001994)2.26189371
76Irregular epiphyses (HP:0010582)2.25177752
77Microvesicular hepatic steatosis (HP:0001414)2.24550348
78Respiratory difficulties (HP:0002880)2.23691047
79Increased intramyocellular lipid droplets (HP:0012240)2.23567972
80Diaphragmatic weakness (HP:0009113)2.23352917
81Postnatal microcephaly (HP:0005484)2.22962547
82Secondary amenorrhea (HP:0000869)2.20734985
83Megaloblastic anemia (HP:0001889)2.19027094
84Lactic acidosis (HP:0003128)2.18535333
85Abnormality of T cell physiology (HP:0011840)2.18528947
86Agnosia (HP:0010524)2.18006391
87Abnormality of chromosome stability (HP:0003220)2.16265620
88Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.14954439
89Exercise-induced myalgia (HP:0003738)2.14909206
90Lymphoma (HP:0002665)2.14601859
91Lethargy (HP:0001254)2.13949738
92Meckel diverticulum (HP:0002245)2.12733934
93Premature ovarian failure (HP:0008209)2.12217863
94Truncus arteriosus (HP:0001660)2.11236050
95Sparse eyelashes (HP:0000653)2.10593187
96Brushfield spots (HP:0001088)2.10491629
9711 pairs of ribs (HP:0000878)2.09113749
98IgG deficiency (HP:0004315)2.08882224
99Myelodysplasia (HP:0002863)2.08542344
100Absent thumb (HP:0009777)2.07793352
101Cholecystitis (HP:0001082)2.07627444
102Abnormal gallbladder physiology (HP:0012438)2.07627444
103Emotional lability (HP:0000712)2.07230027
104Abnormality of the ileum (HP:0001549)2.06845723
105Elevated erythrocyte sedimentation rate (HP:0003565)2.06298868
106Colon cancer (HP:0003003)2.06075425
107Optic disc pallor (HP:0000543)2.05971612
108Acute encephalopathy (HP:0006846)2.04778392
109Abnormality of pyrimidine metabolism (HP:0004353)2.03254205
110Atrophy/Degeneration involving motor neurons (HP:0007373)2.01952603
111Abnormality of reticulocytes (HP:0004312)2.01556209
112Retinal dysplasia (HP:0007973)2.01437322
113Type 2 muscle fiber atrophy (HP:0003554)1.98896205
114Hypertensive crisis (HP:0100735)1.98712781
115Hyperthyroidism (HP:0000836)1.96673859
116Muscle fiber atrophy (HP:0100295)1.94601402
117Respiratory failure (HP:0002878)1.92461817
118Personality changes (HP:0000751)1.92030315
119Absent epiphyses (HP:0010577)1.90865909
120Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.90865909
121Horseshoe kidney (HP:0000085)1.90184701
122Increased muscle lipid content (HP:0009058)1.89783614
123Optic nerve coloboma (HP:0000588)1.89066464
124Duplicated collecting system (HP:0000081)1.88244106
125Trismus (HP:0000211)1.86962803
126Exercise intolerance (HP:0003546)1.86671940
127Abnormality of T cells (HP:0002843)1.85337658
128Hypokinesia (HP:0002375)1.84639662
129Exercise-induced muscle cramps (HP:0003710)1.82868040
130Leukodystrophy (HP:0002415)1.80594658
131Death in infancy (HP:0001522)1.78191620
132Muscle stiffness (HP:0003552)1.75271404
133Hypoplasia of the thymus (HP:0000778)1.74008306
134Squamous cell carcinoma (HP:0002860)1.73033197
135Abnormality of the umbilical cord (HP:0010881)1.71284743
136Self-mutilation (HP:0000742)1.71197323
137Gliosis (HP:0002171)1.70648789
138Reticulocytosis (HP:0001923)1.70351300
139Redundant skin (HP:0001582)1.67579838
140Severe muscular hypotonia (HP:0006829)1.66538128
141Unsteady gait (HP:0002317)1.65890159
142Absent rod-and cone-mediated responses on ERG (HP:0007688)1.63732532
143J-shaped sella turcica (HP:0002680)1.62467111
144Seborrheic dermatitis (HP:0001051)1.61893294
145Aplasia/Hypoplasia of the thymus (HP:0010515)1.61380359

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB15.38286141
2VRK24.32792852
3WEE14.17735105
4STK164.00917740
5EIF2AK13.62407449
6NME23.16299347
7TRIB32.78077823
8TESK22.70332191
9EIF2AK32.53719300
10CDC72.51800722
11ACVR1B2.47968150
12SMG12.32782044
13PLK42.12546552
14VRK11.97004697
15TSSK61.95794474
16BRSK21.88737422
17PIM21.87546094
18SRPK11.87150502
19MAP4K11.81148893
20NEK21.58561626
21BCKDK1.53824598
22ERN11.52980746
23MAP4K21.42452259
24PLK11.41168350
25DYRK31.38309677
26CCNB11.37439942
27TTK1.35745994
28SIK11.35598816
29BLK1.33696926
30KDR1.33041326
31MUSK1.32563682
32TESK11.31401947
33IRAK31.31107990
34PASK1.26085832
35MKNK11.22095185
36NEK11.21058044
37BRAF1.20852518
38ARAF1.19171227
39BRSK11.18518121
40CDK71.16430555
41IRAK41.16242291
42ATR1.14379020
43AURKB1.13095239
44PRKD31.12766489
45TAOK21.09322892
46AURKA1.08315091
47MAP2K71.07655562
48MST41.06449840
49CDK191.06410344
50RPS6KA41.03126349
51CDK81.02204607
52CSNK1A1L1.01691981
53TLK11.00502354
54MAP2K20.97918926
55MAP3K110.97518126
56TXK0.97315540
57MAP3K80.95908306
58ZAP700.94658382
59NME10.94536579
60PDK40.94326585
61PDK30.94326585
62RPS6KB20.91854438
63PKN20.87055472
64EPHA20.86638376
65CSNK1G10.86251196
66SCYL20.85846524
67TEC0.85650654
68CHEK20.84582515
69KIT0.84233573
70TNK20.83381031
71PAK40.83126712
72CSNK1G20.80536066
73STK100.79726359
74PLK30.78008152
75TAOK10.77902155
76BTK0.75444108
77PBK0.74525579
78EIF2AK20.74407160
79ABL20.74241364
80PIM10.73457515
81PAK10.72828879
82CDK40.70657995
83DAPK30.70560044
84ZAK0.69102151
85TGFBR10.68900349
86CSNK2A10.67646177
87LIMK10.65479445
88NUAK10.65294201
89LRRK20.65224061
90MAP2K30.65069097
91MAP3K120.63959741
92EEF2K0.63566115
93CSF1R0.62317025
94CHEK10.62306258
95FLT30.60616026
96CSNK2A20.60251699
97MKNK20.58965032
98STK40.58144400
99TYK20.57797144
100SYK0.54962543
101IKBKB0.54158420
102ICK0.53611213
103RPS6KA50.52845430
104PRKD20.51464074
105MAPK110.51460708
106LYN0.50919387
107DYRK20.49748895
108MAPKAPK50.48197606
109AKT20.47258078
110MAP3K100.46809959
111DAPK10.45666356
112TAOK30.45345905
113TBK10.44523608
114CAMK2G0.44445304
115RAF10.43316662
116CLK10.41424313
117CDK11A0.40844931
118MAPKAPK30.40500636
119CDK140.36967586
120PRKCI0.36818744
121RPS6KL10.36614392
122RPS6KC10.36614392
123JAK30.36506822
124ILK0.36083123
125GRK60.35960089
126CDK20.35378534
127PDK20.34849000
128CSNK1G30.33616262
129CDK90.32554246
130RPS6KA10.32360331
131RPS6KA60.30550670
132LCK0.30366769
133CDK150.29891796
134PRPF4B0.29123070
135ATM0.29078916
136RPS6KA20.28748299
137CDK180.25431472
138LMTK20.25123689
139MAPKAPK20.21264199
140CDK10.21002688

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.64964633
2Proteasome_Homo sapiens_hsa030504.51562262
3Ribosome_Homo sapiens_hsa030103.81044234
4Mismatch repair_Homo sapiens_hsa034303.77330395
5RNA polymerase_Homo sapiens_hsa030203.65557786
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.26023672
7Pyrimidine metabolism_Homo sapiens_hsa002402.76948887
8Homologous recombination_Homo sapiens_hsa034402.76110269
9Base excision repair_Homo sapiens_hsa034102.73043447
10Spliceosome_Homo sapiens_hsa030402.61177153
11Nucleotide excision repair_Homo sapiens_hsa034202.51207151
12RNA transport_Homo sapiens_hsa030132.35776802
13One carbon pool by folate_Homo sapiens_hsa006701.89316784
14Cell cycle_Homo sapiens_hsa041101.87626080
15Basal transcription factors_Homo sapiens_hsa030221.80650513
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.79303411
17Fanconi anemia pathway_Homo sapiens_hsa034601.77000060
18Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.71396493
19Vitamin B6 metabolism_Homo sapiens_hsa007501.66576244
20Protein export_Homo sapiens_hsa030601.65719772
21Folate biosynthesis_Homo sapiens_hsa007901.60854179
22Non-homologous end-joining_Homo sapiens_hsa034501.60763809
23Purine metabolism_Homo sapiens_hsa002301.54662305
24RNA degradation_Homo sapiens_hsa030181.52932461
25Pentose phosphate pathway_Homo sapiens_hsa000301.40855593
26Parkinsons disease_Homo sapiens_hsa050121.39549244
27Oxidative phosphorylation_Homo sapiens_hsa001901.39262736
28Huntingtons disease_Homo sapiens_hsa050161.18583893
29Cysteine and methionine metabolism_Homo sapiens_hsa002701.17164313
30Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.16075369
31Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.14442785
32Sulfur relay system_Homo sapiens_hsa041221.13014788
33p53 signaling pathway_Homo sapiens_hsa041151.12477164
34Epstein-Barr virus infection_Homo sapiens_hsa051691.09482923
35Drug metabolism - other enzymes_Homo sapiens_hsa009831.09474960
36Glutathione metabolism_Homo sapiens_hsa004801.02157202
37Antigen processing and presentation_Homo sapiens_hsa046120.99354262
38Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.95359624
39Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.91552286
40Primary immunodeficiency_Homo sapiens_hsa053400.90779064
41Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.89745830
42Cyanoamino acid metabolism_Homo sapiens_hsa004600.88559240
43Biosynthesis of amino acids_Homo sapiens_hsa012300.87668696
44Cardiac muscle contraction_Homo sapiens_hsa042600.83146817
45Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.82008568
46Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.79559776
47Sulfur metabolism_Homo sapiens_hsa009200.76964233
48Phenylalanine metabolism_Homo sapiens_hsa003600.75830067
49Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.73553389
50Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.72776906
51Carbon metabolism_Homo sapiens_hsa012000.72541182
52Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.72393795
53Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.71307239
54mRNA surveillance pathway_Homo sapiens_hsa030150.70759011
55Herpes simplex infection_Homo sapiens_hsa051680.67287928
56Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.66820744
57Selenocompound metabolism_Homo sapiens_hsa004500.64061114
58Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.63401961
59Alzheimers disease_Homo sapiens_hsa050100.62494242
60Vibrio cholerae infection_Homo sapiens_hsa051100.61675063
61Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.60844143
62Metabolic pathways_Homo sapiens_hsa011000.60255007
63Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.59729098
64Fructose and mannose metabolism_Homo sapiens_hsa000510.59310370
65Tyrosine metabolism_Homo sapiens_hsa003500.58656365
66Systemic lupus erythematosus_Homo sapiens_hsa053220.58248162
67N-Glycan biosynthesis_Homo sapiens_hsa005100.56570512
68Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.56189201
69Alcoholism_Homo sapiens_hsa050340.53849505
70Legionellosis_Homo sapiens_hsa051340.53783307
71Glycosaminoglycan degradation_Homo sapiens_hsa005310.53544292
72Fatty acid elongation_Homo sapiens_hsa000620.52998432
73Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.52282445
74Regulation of autophagy_Homo sapiens_hsa041400.49650463
752-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.47108213
76Other glycan degradation_Homo sapiens_hsa005110.46680433
77Allograft rejection_Homo sapiens_hsa053300.45611023
78Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.44655128
79Viral carcinogenesis_Homo sapiens_hsa052030.44124791
80Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.43590564
81Arginine and proline metabolism_Homo sapiens_hsa003300.43221713
82Graft-versus-host disease_Homo sapiens_hsa053320.43054525
83Pyruvate metabolism_Homo sapiens_hsa006200.42142671
84Measles_Homo sapiens_hsa051620.41203549
85Fatty acid metabolism_Homo sapiens_hsa012120.40233740
86Intestinal immune network for IgA production_Homo sapiens_hsa046720.40036432
87Shigellosis_Homo sapiens_hsa051310.39946693
88Galactose metabolism_Homo sapiens_hsa000520.39226758
89Arachidonic acid metabolism_Homo sapiens_hsa005900.37636007
90Apoptosis_Homo sapiens_hsa042100.34473411
91SNARE interactions in vesicular transport_Homo sapiens_hsa041300.34193761
92Oocyte meiosis_Homo sapiens_hsa041140.33983670
93Steroid biosynthesis_Homo sapiens_hsa001000.33002619
94Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.29574780
95Collecting duct acid secretion_Homo sapiens_hsa049660.29514490
96beta-Alanine metabolism_Homo sapiens_hsa004100.29256163
97Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.28470131
98Renin-angiotensin system_Homo sapiens_hsa046140.28256429
99NF-kappa B signaling pathway_Homo sapiens_hsa040640.27821906
100Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.27278079
101Peroxisome_Homo sapiens_hsa041460.26575720
102RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.24628460
103Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.23172921
104Central carbon metabolism in cancer_Homo sapiens_hsa052300.22463337
105Synaptic vesicle cycle_Homo sapiens_hsa047210.22275656
106Hematopoietic cell lineage_Homo sapiens_hsa046400.22256475
107Glycerophospholipid metabolism_Homo sapiens_hsa005640.19518693
108Vitamin digestion and absorption_Homo sapiens_hsa049770.19326798
109Bladder cancer_Homo sapiens_hsa052190.18997215
110Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.18914578
111HTLV-I infection_Homo sapiens_hsa051660.18556594
112Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.18423370
113Thyroid cancer_Homo sapiens_hsa052160.17091909
114Propanoate metabolism_Homo sapiens_hsa006400.16929863
115Lysine degradation_Homo sapiens_hsa003100.16584456
116AMPK signaling pathway_Homo sapiens_hsa041520.16468706
117Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.16445292
118Butanoate metabolism_Homo sapiens_hsa006500.16333869
119Linoleic acid metabolism_Homo sapiens_hsa005910.16112054
120Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.16075039
121NOD-like receptor signaling pathway_Homo sapiens_hsa046210.16041572
122Pentose and glucuronate interconversions_Homo sapiens_hsa000400.15616243
123Asthma_Homo sapiens_hsa053100.13633801
124Autoimmune thyroid disease_Homo sapiens_hsa053200.12862985
125Leishmaniasis_Homo sapiens_hsa051400.12070637
126Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.11043599
127Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.10658863

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »