NUDT16L1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1base-excision repair, AP site formation (GO:0006285)5.77148131
2ribosomal small subunit assembly (GO:0000028)5.76501215
3viral transcription (GO:0019083)5.32203038
4L-methionine biosynthetic process from methylthioadenosine (GO:0019509)5.11355991
5translational termination (GO:0006415)5.04863691
6ATP synthesis coupled proton transport (GO:0015986)5.00461012
7energy coupled proton transport, down electrochemical gradient (GO:0015985)5.00461012
8DNA deamination (GO:0045006)4.97675469
9ribosomal small subunit biogenesis (GO:0042274)4.94186675
10mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.91301074
11cotranslational protein targeting to membrane (GO:0006613)4.83627994
12SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.81942464
13protein targeting to ER (GO:0045047)4.73146356
14regulation of mitochondrial translation (GO:0070129)4.60237014
15protein localization to endoplasmic reticulum (GO:0070972)4.56934957
16establishment of protein localization to endoplasmic reticulum (GO:0072599)4.52460215
17translational elongation (GO:0006414)4.41918432
18pyrimidine nucleotide catabolic process (GO:0006244)4.41169847
19peptidyl-arginine omega-N-methylation (GO:0035247)4.37584179
20deoxyribonucleotide catabolic process (GO:0009264)4.36017337
21purine deoxyribonucleotide catabolic process (GO:0009155)4.32820653
22mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.24499928
23proteasome assembly (GO:0043248)4.24308081
24negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.16967922
25deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.14673490
26maturation of SSU-rRNA (GO:0030490)4.13367315
27viral life cycle (GO:0019058)4.13049998
28chaperone-mediated protein transport (GO:0072321)4.11719182
29termination of RNA polymerase III transcription (GO:0006386)4.05257191
30transcription elongation from RNA polymerase III promoter (GO:0006385)4.05257191
31cellular protein complex disassembly (GO:0043624)4.00279605
32deoxyribose phosphate catabolic process (GO:0046386)3.96200666
33mitochondrial respiratory chain complex I assembly (GO:0032981)3.92620845
34NADH dehydrogenase complex assembly (GO:0010257)3.92620845
35mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.92620845
36establishment of protein localization to mitochondrial membrane (GO:0090151)3.91832315
37negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.91005310
38negative regulation of ligase activity (GO:0051352)3.91005310
39rRNA modification (GO:0000154)3.89922832
40protein complex biogenesis (GO:0070271)3.88960972
41translational initiation (GO:0006413)3.84957541
42nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.81299710
43respiratory electron transport chain (GO:0022904)3.80184445
44translation (GO:0006412)3.79768571
45establishment of integrated proviral latency (GO:0075713)3.78752981
46electron transport chain (GO:0022900)3.77896230
47amino acid salvage (GO:0043102)3.75413007
48L-methionine salvage (GO:0071267)3.75413007
49L-methionine biosynthetic process (GO:0071265)3.75413007
50histone arginine methylation (GO:0034969)3.74724531
51regulation of cellular amino acid metabolic process (GO:0006521)3.74601874
52central nervous system myelination (GO:0022010)3.72307649
53axon ensheathment in central nervous system (GO:0032291)3.72307649
54protein insertion into membrane (GO:0051205)3.69700349
55cullin deneddylation (GO:0010388)3.67960673
56negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.65706357
57respiratory chain complex IV assembly (GO:0008535)3.65305727
58pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.64590106
59protein complex disassembly (GO:0043241)3.61102425
60DNA damage response, detection of DNA damage (GO:0042769)3.60606679
61regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.56477074
62positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.55411288
63mitochondrial respiratory chain complex assembly (GO:0033108)3.55255221
64antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.52521457
65DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.50798532
66protein deneddylation (GO:0000338)3.50665275
67protein maturation by protein folding (GO:0022417)3.49417041
68nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.47627732
69GTP biosynthetic process (GO:0006183)3.46717043
70intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.44802397
71signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.44802397
72macromolecular complex disassembly (GO:0032984)3.40337715
732-deoxyribonucleotide metabolic process (GO:0009394)3.40039903
74peptidyl-arginine methylation (GO:0018216)3.39907325
75peptidyl-arginine N-methylation (GO:0035246)3.39907325
767-methylguanosine mRNA capping (GO:0006370)3.39538864
77protein localization to mitochondrion (GO:0070585)3.39322479
78signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.38873798
79signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.38873798
80signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.38873798
81exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.37055283
82metallo-sulfur cluster assembly (GO:0031163)3.36125393
83iron-sulfur cluster assembly (GO:0016226)3.36125393
847-methylguanosine RNA capping (GO:0009452)3.33502865
85RNA capping (GO:0036260)3.33502865
86establishment of viral latency (GO:0019043)3.33344400
87inner mitochondrial membrane organization (GO:0007007)3.29202017
88peptidyl-histidine modification (GO:0018202)3.28685684
89signal transduction involved in DNA damage checkpoint (GO:0072422)3.27603049
90signal transduction involved in DNA integrity checkpoint (GO:0072401)3.27603049
91signal transduction involved in cell cycle checkpoint (GO:0072395)3.23987766
92anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.23563950
93RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.23454672
94tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.23454672
95guanosine-containing compound biosynthetic process (GO:1901070)3.21182589
96antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.20361931
97purine deoxyribonucleotide metabolic process (GO:0009151)3.20092863
98protein targeting to membrane (GO:0006612)3.16744609
99energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.14301516
100ATP hydrolysis coupled proton transport (GO:0015991)3.14301516
101ribonucleoprotein complex biogenesis (GO:0022613)3.13766202
102cellular component biogenesis (GO:0044085)3.12888377
103protein targeting to mitochondrion (GO:0006626)3.06643100
104deoxyribose phosphate metabolic process (GO:0019692)3.04671540
105sequestering of actin monomers (GO:0042989)3.04598814
106purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.04177636
107UTP biosynthetic process (GO:0006228)3.03519698
108Arp2/3 complex-mediated actin nucleation (GO:0034314)3.03240306
109GDP-mannose metabolic process (GO:0019673)3.01882157
110pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.01792489
111spliceosomal snRNP assembly (GO:0000387)3.01189915
112regulation of autophagic vacuole assembly (GO:2000785)3.00843860
113mannosylation (GO:0097502)3.00360543
114establishment of protein localization to mitochondrion (GO:0072655)3.00345750
115purine nucleoside triphosphate biosynthetic process (GO:0009145)2.99790368
116fatty acid elongation (GO:0030497)2.98338354
117rRNA processing (GO:0006364)2.98296120
118ribosomal large subunit biogenesis (GO:0042273)2.96425385
119cytochrome complex assembly (GO:0017004)2.96025581
120CTP metabolic process (GO:0046036)2.95288767
121CTP biosynthetic process (GO:0006241)2.95288767
122hydrogen ion transmembrane transport (GO:1902600)2.94952294
123oxidative phosphorylation (GO:0006119)2.94528421
124pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.94047910
125pentose metabolic process (GO:0019321)2.93689707
126positive regulation of TOR signaling (GO:0032008)2.93222661
127regulation of cellular amine metabolic process (GO:0033238)2.92287352
128protein neddylation (GO:0045116)2.91831234
129nuclear-transcribed mRNA catabolic process (GO:0000956)2.91735735
130purine ribonucleotide transport (GO:0015868)2.89139765
131deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.88538906
132ATP biosynthetic process (GO:0006754)2.88344684
133GPI anchor biosynthetic process (GO:0006506)2.88115482
134positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.88039055
135adenine nucleotide transport (GO:0051503)2.87561099
136viral protein processing (GO:0019082)2.87520634
137protein localization to cilium (GO:0061512)2.86811052
138pseudouridine synthesis (GO:0001522)2.86154594
139preassembly of GPI anchor in ER membrane (GO:0016254)2.85401991
140C-terminal protein lipidation (GO:0006501)2.85288806

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat5.40832201
2NOTCH1_17114293_ChIP-ChIP_T-ALL_Human5.27027003
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.53775911
4GABP_17652178_ChIP-ChIP_JURKAT_Human4.30355910
5EST1_17652178_ChIP-ChIP_JURKAT_Human4.26901902
6JARID1A_20064375_ChIP-Seq_MESCs_Mouse4.00325519
7HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.77085088
8MYC_18555785_ChIP-Seq_MESCs_Mouse3.70578161
9* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.64672106
10E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.62087146
11ETS1_20019798_ChIP-Seq_JURKAT_Human3.60156418
12CREB1_15753290_ChIP-ChIP_HEK293T_Human3.36038124
13ELF1_17652178_ChIP-ChIP_JURKAT_Human3.34687972
14HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.97721161
15MYC_18358816_ChIP-ChIP_MESCs_Mouse2.96944675
16CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.84461773
17PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.79460041
18THAP11_20581084_ChIP-Seq_MESCs_Mouse2.68902641
19VDR_23849224_ChIP-Seq_CD4+_Human2.55201007
20YY1_21170310_ChIP-Seq_MESCs_Mouse2.42021963
21SRF_21415370_ChIP-Seq_HL-1_Mouse2.39349711
22CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.37917248
23* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.37170301
24XRN2_22483619_ChIP-Seq_HELA_Human2.36639316
25TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.32889791
26E2F1_18555785_ChIP-Seq_MESCs_Mouse2.20515947
27MYC_19079543_ChIP-ChIP_MESCs_Mouse2.16818515
28FOXP3_21729870_ChIP-Seq_TREG_Human2.12873227
29SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.05953824
30FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.04594508
31PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.02538772
32FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.01134983
33LXR_22292898_ChIP-Seq_THP-1_Human2.00129419
34DCP1A_22483619_ChIP-Seq_HELA_Human1.95304522
35GABP_19822575_ChIP-Seq_HepG2_Human1.93411360
36ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.92420024
37CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.91597675
38* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.90102644
39P68_20966046_ChIP-Seq_HELA_Human1.88876161
40TTF2_22483619_ChIP-Seq_HELA_Human1.87314108
41BCL6_27268052_Chip-Seq_Bcells_Human1.75827880
42ELF1_20517297_ChIP-Seq_JURKAT_Human1.65659519
43DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.65172489
44DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.64762390
45* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.61940944
46ELK1_19687146_ChIP-ChIP_HELA_Human1.61012754
47CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.60918684
48* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.58175566
49HOXB4_20404135_ChIP-ChIP_EML_Mouse1.56040389
50CTCF_18555785_ChIP-Seq_MESCs_Mouse1.51208281
51* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.50219136
52BCOR_27268052_Chip-Seq_Bcells_Human1.49655201
53* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.48404412
54SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.44312634
55CIITA_25753668_ChIP-Seq_RAJI_Human1.42997287
56* MAF_26560356_Chip-Seq_TH2_Human1.40610526
57* SA1_27219007_Chip-Seq_ERYTHROID_Human1.40572618
58PHF8_20622854_ChIP-Seq_HELA_Human1.40207958
59E2F1_20622854_ChIP-Seq_HELA_Human1.38574227
60SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.37519676
61MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.37305081
62TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.36648422
63E2F7_22180533_ChIP-Seq_HELA_Human1.36638276
64* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.35983466
65PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.35334257
66THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.35011131
67* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.33058917
68POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.31511865
69IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.29776888
70CTCF_27219007_Chip-Seq_Bcells_Human1.29690974
71CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.29292310
72SA1_27219007_Chip-Seq_Bcells_Human1.29210824
73ELK1_22589737_ChIP-Seq_MCF10A_Human1.28628625
74HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.28500419
75ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.28131564
76CTCF_21964334_Chip-Seq_Bcells_Human1.26291228
77YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.25758462
78RACK7_27058665_Chip-Seq_MCF-7_Human1.25503950
79CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.24024962
80RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.23252493
81* RARB_24833708_ChIP-Seq_LIVER_Mouse1.21229192
82SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.19912812
83CTCF_20526341_ChIP-Seq_ESCs_Human1.17926155
84UTX_26944678_Chip-Seq_JUKART_Human1.17481002
85CTCF_27219007_Chip-Seq_ERYTHROID_Human1.15226801
86SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.15058622
87MYC_22102868_ChIP-Seq_BL_Human1.14818584
88BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.14179225
89ERG_21242973_ChIP-ChIP_JURKAT_Human1.13162539
90GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.12039827
91SRY_22984422_ChIP-ChIP_TESTIS_Rat1.12036835
92SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.10894873
93SOX2_18555785_ChIP-Seq_MESCs_Mouse1.10123123
94EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.09544781
95SMC4_20622854_ChIP-Seq_HELA_Human1.09292129
96KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.09225478
97ELK3_25401928_ChIP-Seq_HUVEC_Human1.09095003
98* RARA_24833708_ChIP-Seq_LIVER_Mouse1.08264086
99CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.08245075
100FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.08115832
101E2F4_17652178_ChIP-ChIP_JURKAT_Human1.08061725
102POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.07143209
103CTCF_21964334_ChIP-Seq_BJAB-B_Human1.07069025
104ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.05592051
105SPI1_23547873_ChIP-Seq_NB4_Human1.05525113
106TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.05491291
107MYCN_18555785_ChIP-Seq_MESCs_Mouse1.04737723
108MYC_18940864_ChIP-ChIP_HL60_Human1.04271793
109NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.04078750
110MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.03935179
111KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.03341761
112LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.02093329
113ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.98916800
114YY1_22570637_ChIP-Seq_MALME-3M_Human0.98809936
115FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.98010839
116CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.94323517
117STAT1_20625510_ChIP-Seq_HELA_Human0.91670559
118SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.91511479
119NANOG_18555785_ChIP-Seq_MESCs_Mouse0.90778786
120CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.85350669
121PU.1_20513432_ChIP-Seq_Bcells_Mouse0.84535625
122MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.83299952
123POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.82461657
124* FOXP1_21924763_ChIP-Seq_HESCs_Human0.82186939
125IRF1_19129219_ChIP-ChIP_H3396_Human0.81588015
126CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.81147356
127SCL_19346495_ChIP-Seq_HPC-7_Human0.80895210
128KDM5A_27292631_Chip-Seq_BREAST_Human0.80692469
129SOX2_18692474_ChIP-Seq_MEFs_Mouse0.79860397
130* VDR_21846776_ChIP-Seq_THP-1_Human0.78890526
131RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.77607567
132CTCF_26484167_Chip-Seq_Bcells_Mouse0.77527281
133PADI4_21655091_ChIP-ChIP_MCF-7_Human0.76703933
134HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.74456791
135TET1_21451524_ChIP-Seq_MESCs_Mouse0.74119577
136OCT4_18692474_ChIP-Seq_MEFs_Mouse0.73420701
137TBX5_21415370_ChIP-Seq_HL-1_Mouse0.73008575
138MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.71605416

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006292_abnormal_olfactory_placode3.05861953
2MP0005423_abnormal_somatic_nervous2.78573377
3MP0001905_abnormal_dopamine_level2.72124608
4MP0005075_abnormal_melanosome_morpholog2.70490276
5MP0001529_abnormal_vocalization2.69654445
6MP0003880_abnormal_central_pattern2.44405609
7MP0005174_abnormal_tail_pigmentation2.35596643
8MP0009379_abnormal_foot_pigmentation2.33803257
9MP0004133_heterotaxia2.30634493
10MP0005409_darkened_coat_color2.29349972
11MP0001986_abnormal_taste_sensitivity2.15447892
12MP0000372_irregular_coat_pigmentation2.15323135
13MP0000015_abnormal_ear_pigmentation2.05028276
14MP0008789_abnormal_olfactory_epithelium1.98571725
15MP0005058_abnormal_lysosome_morphology1.96173187
16MP0003787_abnormal_imprinting1.95443060
17MP0000678_abnormal_parathyroid_gland1.90225463
18MP0003011_delayed_dark_adaptation1.88262805
19MP0009840_abnormal_foam_cell1.83452675
20MP0003315_abnormal_perineum_morphology1.80065101
21MP0000920_abnormal_myelination1.78842247
22MP0000049_abnormal_middle_ear1.76516743
23MP0005499_abnormal_olfactory_system1.76488153
24MP0005394_taste/olfaction_phenotype1.76488153
25MP0001849_ear_inflammation1.75790828
26MP0002822_catalepsy1.75514830
27MP0002938_white_spotting1.72008409
28MP0000750_abnormal_muscle_regeneration1.68050988
29MP0002653_abnormal_ependyma_morphology1.67380750
30MP0003136_yellow_coat_color1.66797709
31MP0003786_premature_aging1.66626967
32MP0003693_abnormal_embryo_hatching1.64157889
33MP0000681_abnormal_thyroid_gland1.60493421
34MP0005671_abnormal_response_to1.59787271
35MP0008058_abnormal_DNA_repair1.57975676
36MP0006036_abnormal_mitochondrial_physio1.56731114
37MP0005377_hearing/vestibular/ear_phenot1.52917423
38MP0003878_abnormal_ear_physiology1.52917423
39MP0008932_abnormal_embryonic_tissue1.51502668
40MP0002095_abnormal_skin_pigmentation1.50406221
41MP0002736_abnormal_nociception_after1.48898822
42MP0003806_abnormal_nucleotide_metabolis1.48294359
43MP0001968_abnormal_touch/_nociception1.47029657
44MP0002272_abnormal_nervous_system1.44939152
45MP0003763_abnormal_thymus_physiology1.44692059
46MP0002396_abnormal_hematopoietic_system1.42921376
47MP0002751_abnormal_autonomic_nervous1.42597914
48MP0004957_abnormal_blastocyst_morpholog1.42531740
49MP0004142_abnormal_muscle_tone1.42040252
50MP0001485_abnormal_pinna_reflex1.40048751
51MP0003122_maternal_imprinting1.39801926
52MP0001727_abnormal_embryo_implantation1.38792347
53MP0008057_abnormal_DNA_replication1.36650452
54MP0001764_abnormal_homeostasis1.33017482
55MP0010030_abnormal_orbit_morphology1.30600012
56MP0005083_abnormal_biliary_tract1.28721429
57MP0008260_abnormal_autophagy1.28003278
58MP0003866_abnormal_defecation1.25890589
59MP0003186_abnormal_redox_activity1.25778577
60MP0002163_abnormal_gland_morphology1.25220496
61MP0000358_abnormal_cell_content/1.25011492
62MP0002102_abnormal_ear_morphology1.23307410
63MP0008995_early_reproductive_senescence1.22786915
64MP0005330_cardiomyopathy1.22460051
65MP0003137_abnormal_impulse_conducting1.22246627
66MP0002148_abnormal_hypersensitivity_rea1.21677203
67MP0005645_abnormal_hypothalamus_physiol1.21659068
68MP0003938_abnormal_ear_development1.20600376
69MP0009333_abnormal_splenocyte_physiolog1.18547810
70MP0000631_abnormal_neuroendocrine_gland1.18239206
71MP0001963_abnormal_hearing_physiology1.18161871
72MP0006072_abnormal_retinal_apoptosis1.16862512
73MP0000751_myopathy1.14542070
74MP0003718_maternal_effect1.12498956
75MP0006054_spinal_hemorrhage1.12085350
76MP0005451_abnormal_body_composition1.07831346
77MP0002160_abnormal_reproductive_system1.07659825
78MP0002909_abnormal_adrenal_gland1.07267778
79MP0001502_abnormal_circadian_rhythm1.05122795
80MP0003172_abnormal_lysosome_physiology1.04900350
81MP0000465_gastrointestinal_hemorrhage1.04174963
82MP0005408_hypopigmentation1.03724378
83MP0002638_abnormal_pupillary_reflex1.02371221
84MP0001919_abnormal_reproductive_system1.02150302
85MP0005584_abnormal_enzyme/coenzyme_acti1.01383965
86MP0001661_extended_life_span1.01060742
87MP0003436_decreased_susceptibility_to1.00631898
88MP0004742_abnormal_vestibular_system1.00609847
89MP0008877_abnormal_DNA_methylation1.00227259
90MP0006035_abnormal_mitochondrial_morpho0.99702898
91MP0000538_abnormal_urinary_bladder0.98219419
92MP0002132_abnormal_respiratory_system0.97680594
93MP0004270_analgesia0.96875696
94MP0003077_abnormal_cell_cycle0.94888590
95MP0000685_abnormal_immune_system0.93480373
96MP0005379_endocrine/exocrine_gland_phen0.93447615
97MP0004043_abnormal_pH_regulation0.93052196
98MP0003123_paternal_imprinting0.92995313
99MP0001970_abnormal_pain_threshold0.92849522
100MP0000490_abnormal_crypts_of0.91739779
101MP0004885_abnormal_endolymph0.90648822
102MP0006276_abnormal_autonomic_nervous0.90377895
103MP0000749_muscle_degeneration0.89643294
104MP0001542_abnormal_bone_strength0.88990101
105MP0002064_seizures0.88979272
106MP0001984_abnormal_olfaction0.88918542
107MP0010094_abnormal_chromosome_stability0.88524304
108MP0000689_abnormal_spleen_morphology0.88444774
109MP0002398_abnormal_bone_marrow0.88133030
110MP0002752_abnormal_somatic_nervous0.87885717
111MP0002733_abnormal_thermal_nociception0.87637110
112MP0000026_abnormal_inner_ear0.87342267
113MP0002723_abnormal_immune_serum0.85091650
114MP0004858_abnormal_nervous_system0.84833485
115MP0002229_neurodegeneration0.82466288
116MP0002734_abnormal_mechanical_nocicepti0.81658241
117MP0005171_absent_coat_pigmentation0.81069091
118MP0005646_abnormal_pituitary_gland0.80896807
119MP0001188_hyperpigmentation0.80412729
120MP0009745_abnormal_behavioral_response0.80179023
121MP0004381_abnormal_hair_follicle0.79652044
122MP0002277_abnormal_respiratory_mucosa0.79637219
123MP0002420_abnormal_adaptive_immunity0.79620850
124MP0004859_abnormal_synaptic_plasticity0.78312495
125MP0003121_genomic_imprinting0.78186196
126MP0002837_dystrophic_cardiac_calcinosis0.77614858
127MP0002722_abnormal_immune_system0.77390868
128MP0009697_abnormal_copulation0.76422000
129MP0002234_abnormal_pharynx_morphology0.76385013
130MP0003879_abnormal_hair_cell0.76174728
131MP0005310_abnormal_salivary_gland0.75976472
132MP0000716_abnormal_immune_system0.75480799
133MP0001819_abnormal_immune_cell0.75160505
134MP0002249_abnormal_larynx_morphology0.74337744
135MP0005253_abnormal_eye_physiology0.74097983
136MP0009785_altered_susceptibility_to0.72427716
137MP0008007_abnormal_cellular_replicative0.71942830
138MP0005025_abnormal_response_to0.71214105
139MP0002882_abnormal_neuron_morphology0.71184762
140MP0002429_abnormal_blood_cell0.70682258
141MP0005332_abnormal_amino_acid0.70099901
142MP0002067_abnormal_sensory_capabilities0.69642283
143MP0008872_abnormal_physiological_respon0.69605480
144MP0005319_abnormal_enzyme/_coenzyme0.69070525
145MP0005551_abnormal_eye_electrophysiolog0.66279602
146MP0009643_abnormal_urine_homeostasis0.66202979
147MP0008875_abnormal_xenobiotic_pharmacok0.66118894

Predicted human phenotypes

RankGene SetZ-score
1Cerebral hypomyelination (HP:0006808)5.13159053
2Acute necrotizing encephalopathy (HP:0006965)5.02130524
3Hepatocellular necrosis (HP:0001404)4.70179096
4Mitochondrial inheritance (HP:0001427)4.57449424
5Abnormal mitochondria in muscle tissue (HP:0008316)4.56863200
6Abnormality of cells of the erythroid lineage (HP:0012130)4.17612821
7Increased CSF lactate (HP:0002490)4.06602845
8Hepatic necrosis (HP:0002605)4.04823072
9Abnormal number of erythroid precursors (HP:0012131)3.98481389
10Acute encephalopathy (HP:0006846)3.96594202
11Stenosis of the external auditory canal (HP:0000402)3.84069775
12Progressive macrocephaly (HP:0004481)3.81431196
13Type I transferrin isoform profile (HP:0003642)3.69957784
14Testicular atrophy (HP:0000029)3.68860168
15Increased serum pyruvate (HP:0003542)3.62599574
16Abnormality of glycolysis (HP:0004366)3.62599574
173-Methylglutaconic aciduria (HP:0003535)3.53181586
18Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.50726088
19Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.50526484
20Decreased activity of mitochondrial respiratory chain (HP:0008972)3.50526484
21Leukodystrophy (HP:0002415)3.36419613
22CNS hypomyelination (HP:0003429)3.32342742
23Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.31297570
24Renal Fanconi syndrome (HP:0001994)3.24154489
25Increased hepatocellular lipid droplets (HP:0006565)3.19729432
26Increased serum lactate (HP:0002151)3.16728273
27Ragged-red muscle fibers (HP:0003200)2.99172251
28Hypothermia (HP:0002045)2.93549333
29Respiratory failure (HP:0002878)2.92391013
30Myokymia (HP:0002411)2.87398670
31Lactic acidosis (HP:0003128)2.86723359
32Reticulocytopenia (HP:0001896)2.85798277
33Severe visual impairment (HP:0001141)2.82539653
34Abnormality of dicarboxylic acid metabolism (HP:0010995)2.77810665
35Dicarboxylic aciduria (HP:0003215)2.77810665
36Macrocytic anemia (HP:0001972)2.76844610
37Lipid accumulation in hepatocytes (HP:0006561)2.76783946
38Aplasia/Hypoplasia of the sacrum (HP:0008517)2.76246881
39True hermaphroditism (HP:0010459)2.74405692
40Abnormal protein N-linked glycosylation (HP:0012347)2.68874721
41Abnormal protein glycosylation (HP:0012346)2.68874721
42Abnormal glycosylation (HP:0012345)2.68874721
43Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.68874721
44Poor suck (HP:0002033)2.67060015
45Exercise intolerance (HP:0003546)2.65660924
46Hyperglycinemia (HP:0002154)2.65034487
47Morphological abnormality of the inner ear (HP:0011390)2.61374977
48Abnormality of cochlea (HP:0000375)2.51584680
49Aplastic anemia (HP:0001915)2.51102962
50Failure to thrive in infancy (HP:0001531)2.48249334
51Increased intramyocellular lipid droplets (HP:0012240)2.47177464
52Myopathic facies (HP:0002058)2.45263252
53Rib fusion (HP:0000902)2.42919798
54Emotional lability (HP:0000712)2.41488070
55Spastic paraparesis (HP:0002313)2.41304056
56Progressive microcephaly (HP:0000253)2.40740449
57CNS demyelination (HP:0007305)2.39300130
58Reduced antithrombin III activity (HP:0001976)2.38968546
59Chronic sinusitis (HP:0011109)2.37809399
60Abnormality of the renal collecting system (HP:0004742)2.35471932
61Pancreatic cysts (HP:0001737)2.32829784
62Cerebral edema (HP:0002181)2.32377929
63Pallor (HP:0000980)2.31551376
64Opisthotonus (HP:0002179)2.31385360
65Exertional dyspnea (HP:0002875)2.28776684
66Muscle fiber atrophy (HP:0100295)2.28211622
67Optic disc pallor (HP:0000543)2.27465822
68Delusions (HP:0000746)2.26391123
69Microretrognathia (HP:0000308)2.24717514
70Methylmalonic aciduria (HP:0012120)2.24679974
71Parakeratosis (HP:0001036)2.22998918
72Postnatal microcephaly (HP:0005484)2.22846346
73Abnormality of magnesium homeostasis (HP:0004921)2.22230338
74Retinal dysplasia (HP:0007973)2.21830378
75Pancreatic fibrosis (HP:0100732)2.21315161
76Lethargy (HP:0001254)2.10987548
77Asplenia (HP:0001746)2.08528524
78Polyphagia (HP:0002591)2.06507959
79Split foot (HP:0001839)2.05480458
80Respiratory difficulties (HP:0002880)2.04843402
81Neuroendocrine neoplasm (HP:0100634)2.03587755
82Cerebral palsy (HP:0100021)2.03449548
83Abnormality of renal resorption (HP:0011038)2.01814799
84Increased muscle lipid content (HP:0009058)2.01653235
85Aplasia/Hypoplasia of the spleen (HP:0010451)2.01512790
86Medial flaring of the eyebrow (HP:0010747)1.99088347
87Thrombocytosis (HP:0001894)1.98431927
88Type 2 muscle fiber atrophy (HP:0003554)1.98280521
89Hypomagnesemia (HP:0002917)1.98017217
90Dry hair (HP:0011359)1.96441576
91Elevated erythrocyte sedimentation rate (HP:0003565)1.96423970
92Congenital malformation of the right heart (HP:0011723)1.95477257
93Double outlet right ventricle (HP:0001719)1.95477257
94Recurrent bronchitis (HP:0002837)1.95352952
95Nasolacrimal duct obstruction (HP:0000579)1.92743991
96Hypoplasia of the thymus (HP:0000778)1.92430692
97Prolonged neonatal jaundice (HP:0006579)1.91701576
98Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.90762448
99Rhabdomyolysis (HP:0003201)1.89309224
100Increased IgM level (HP:0003496)1.88469525
101Hyperglycinuria (HP:0003108)1.87127177
102Myotonia (HP:0002486)1.85836484
103Abnormal gallbladder physiology (HP:0012438)1.83650095
104Cholecystitis (HP:0001082)1.83650095
105Concave nail (HP:0001598)1.83626014
106Microvesicular hepatic steatosis (HP:0001414)1.83172382
107Abnormality of serine family amino acid metabolism (HP:0010894)1.82525830
108Abnormality of glycine metabolism (HP:0010895)1.82525830
109Nephrogenic diabetes insipidus (HP:0009806)1.80645420
110Unsteady gait (HP:0002317)1.80474465
111Optic nerve coloboma (HP:0000588)1.77935921
112Decreased electroretinogram (ERG) amplitude (HP:0000654)1.77052730
113Anencephaly (HP:0002323)1.75788607
114Congenital primary aphakia (HP:0007707)1.73613264
115Pheochromocytoma (HP:0002666)1.72928867
116Gait imbalance (HP:0002141)1.72132661
117IgM deficiency (HP:0002850)1.72103840
118Aplasia/hypoplasia of the uterus (HP:0008684)1.71779928
119Renal salt wasting (HP:0000127)1.70851077
120Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.70346051
121Anomalous pulmonary venous return (HP:0010772)1.69499678
122Partial duplication of thumb phalanx (HP:0009944)1.68716120
12311 pairs of ribs (HP:0000878)1.68664955
124Ketosis (HP:0001946)1.68416200
125Progressive neurologic deterioration (HP:0002344)1.68176298
126Gliosis (HP:0002171)1.67752286
127Vomiting (HP:0002013)1.67495792
128Hyperphosphaturia (HP:0003109)1.66618096
129Abnormality of fatty-acid metabolism (HP:0004359)1.66376918
130Absent thumb (HP:0009777)1.65518285
131Chronic otitis media (HP:0000389)1.65266035
132Abnormality of the heme biosynthetic pathway (HP:0010472)1.64368748
133Broad distal phalanx of finger (HP:0009836)1.64349831
134Progressive muscle weakness (HP:0003323)1.64103751
135Annular pancreas (HP:0001734)1.63644724
136Hypoplastic pelvis (HP:0008839)1.63143242
137Obstructive lung disease (HP:0006536)1.62616777
138Chronic obstructive pulmonary disease (HP:0006510)1.62616777
139Renal tubular dysfunction (HP:0000124)1.60966765
140Renal cortical cysts (HP:0000803)1.60591431
141Hepatosplenomegaly (HP:0001433)1.60327859
142Pancytopenia (HP:0001876)1.60287993
143Truncus arteriosus (HP:0001660)1.58260040
144Severe global developmental delay (HP:0011344)1.57259332
145Abnormal urine phosphate concentration (HP:0012599)1.57090045
146Hypoplastic heart (HP:0001961)1.57047230
147Sclerocornea (HP:0000647)1.56776551
148Generalized aminoaciduria (HP:0002909)1.55928986
149Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.54419415

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK164.42679773
2VRK23.33322898
3BCR3.26225942
4BUB13.01190787
5TNIK2.88811439
6PASK2.82413023
7CDK192.69463903
8STK392.53015108
9TESK22.50397054
10MAPKAPK52.50016407
11NME22.35169207
12VRK12.31381006
13MKNK12.12079733
14NME11.92461341
15MAP3K121.85118896
16WEE11.84689512
17OXSR11.81671802
18MAPK151.80086740
19SIK31.78398063
20GRK61.66369392
21CCNB11.59583733
22CSNK1G31.55202327
23ADRBK21.51109300
24EIF2AK11.47310360
25ARAF1.42616272
26SRPK11.39873070
27UHMK11.39612289
28WNK41.30419279
29TSSK61.29178789
30BRSK21.25521158
31EIF2AK31.24162786
32TRIB31.23174463
33LIMK11.22579154
34BCKDK1.18437893
35TNK21.16994250
36MUSK1.15939207
37ERN11.15466369
38MAP4K11.15351047
39KDR1.14567598
40FLT31.12692493
41SMG11.11953713
42KIT1.11840419
43DYRK21.11144206
44DYRK1B1.10509125
45TLK11.07029097
46TRIM281.05974345
47PLK41.05555146
48PIM21.04669965
49TAOK11.03775668
50MAP2K21.03675555
51CSNK1A1L1.03018008
52TBK11.02341899
53ABL21.02273196
54TGFBR11.01253196
55MAP4K20.99695892
56PDK20.99232413
57MST40.97723273
58PINK10.97342149
59BTK0.91567782
60PBK0.91124827
61RPS6KB20.88680090
62MAP2K60.87530376
63IRAK40.86347589
64DAPK30.85425979
65NEK60.84838477
66BRSK10.84560710
67CASK0.84504272
68IRAK20.84242650
69MAPK130.83012242
70TESK10.82336198
71PRKCI0.82197123
72CLK10.82031454
73CSNK1G20.81499564
74PNCK0.81075954
75TAOK20.79521878
76PRKD20.78156319
77SYK0.77108589
78CSNK1G10.77036315
79DYRK30.75129394
80ILK0.73895193
81CAMKK10.72172669
82SIK10.70653624
83PRKD30.70014091
84TIE10.69052189
85MKNK20.67406425
86IKBKE0.66919985
87MAP3K110.64746870
88SIK20.64465698
89RPS6KA40.64343826
90YES10.63734278
91LRRK20.62916034
92DAPK10.62146304
93BLK0.61927742
94ZAP700.61429010
95RPS6KA50.61425981
96MYLK0.60025611
97TXK0.59649753
98CAMK2B0.58799133
99PKN10.58689027
100BRAF0.58632233
101SCYL20.58257970
102AURKA0.57359292
103FES0.56703948
104WNK30.56643123
105TEC0.54799184
106PRPF4B0.52626602
107PRKCQ0.51987983
108RPS6KA20.50239299
109PAK10.50191783
110PAK40.49528490
111MAP2K30.47918379
112LYN0.47337499
113PRKD10.46787400
114MAP2K40.46023480
115CSF1R0.45552524
116IKBKB0.45537555
117CSNK2A10.45080240
118ROCK20.44829510
119CDK11A0.43500423
120EPHA20.43162693
121CDK140.42854694
122MATK0.41584006
123CDK180.41369137
124MAP3K40.39784240
125PRKCZ0.39697595
126LCK0.38179362
127MAPK120.37675121
128EPHA40.37190380
129NTRK10.36760432
130CDK150.36738127
131CSNK2A20.36610352
132ITK0.36107622
133CAMK2D0.35859182
134MINK10.35821858
135EPHB10.35332715
136CAMK10.35228720
137CDC70.34904229
138PRKCD0.33639231
139RPS6KC10.32864074
140RPS6KL10.32864074
141MAP3K50.32384702
142MARK20.32204041
143CSNK1A10.32192025
144MAP2K70.29591692
145CAMK2G0.29536255
146MARK30.29444093
147BMPR20.29054178
148MAPKAPK20.28531168

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.09748079
2Proteasome_Homo sapiens_hsa030504.46327447
3Oxidative phosphorylation_Homo sapiens_hsa001903.80619025
4RNA polymerase_Homo sapiens_hsa030203.47663621
5Parkinsons disease_Homo sapiens_hsa050123.44777985
6Protein export_Homo sapiens_hsa030603.13424508
7DNA replication_Homo sapiens_hsa030302.99600164
8Spliceosome_Homo sapiens_hsa030402.53547881
92-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.50552093
10Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.42966211
11Alzheimers disease_Homo sapiens_hsa050102.40626167
12Mismatch repair_Homo sapiens_hsa034302.40262246
13Huntingtons disease_Homo sapiens_hsa050162.31803966
14Pyrimidine metabolism_Homo sapiens_hsa002402.12601672
15Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006042.07188672
16Fatty acid elongation_Homo sapiens_hsa000622.03879785
17Nucleotide excision repair_Homo sapiens_hsa034201.84833423
18Homologous recombination_Homo sapiens_hsa034401.77757233
19Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.71619764
20Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.70316884
21Base excision repair_Homo sapiens_hsa034101.69882855
22SNARE interactions in vesicular transport_Homo sapiens_hsa041301.69779674
23Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.64372196
24Folate biosynthesis_Homo sapiens_hsa007901.61697271
25Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.58134887
26Collecting duct acid secretion_Homo sapiens_hsa049661.56799795
27Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.52535155
28Non-homologous end-joining_Homo sapiens_hsa034501.39325681
29Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.38306912
30Vibrio cholerae infection_Homo sapiens_hsa051101.36167170
31Purine metabolism_Homo sapiens_hsa002301.33428280
32RNA degradation_Homo sapiens_hsa030181.24817918
33RNA transport_Homo sapiens_hsa030131.24803544
34Glycosaminoglycan degradation_Homo sapiens_hsa005311.24116801
35Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.23090207
36Basal transcription factors_Homo sapiens_hsa030221.21586866
37Sulfur relay system_Homo sapiens_hsa041221.18467452
38Primary immunodeficiency_Homo sapiens_hsa053401.13974804
39Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.09194624
40Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.07814849
41Galactose metabolism_Homo sapiens_hsa000521.04091276
42Steroid biosynthesis_Homo sapiens_hsa001001.00288711
43Cyanoamino acid metabolism_Homo sapiens_hsa004600.99717477
44Phenylalanine metabolism_Homo sapiens_hsa003600.93214000
45Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.91244269
46Cardiac muscle contraction_Homo sapiens_hsa042600.90344127
47N-Glycan biosynthesis_Homo sapiens_hsa005100.86991382
48Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.83757053
49Other glycan degradation_Homo sapiens_hsa005110.83604613
50Pyruvate metabolism_Homo sapiens_hsa006200.82366598
51Ether lipid metabolism_Homo sapiens_hsa005650.82016770
52Sphingolipid metabolism_Homo sapiens_hsa006000.75976048
53Lysosome_Homo sapiens_hsa041420.68994152
54Metabolic pathways_Homo sapiens_hsa011000.68820715
55Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.64901326
56Arachidonic acid metabolism_Homo sapiens_hsa005900.64121300
57Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.63640353
58Epstein-Barr virus infection_Homo sapiens_hsa051690.63562086
59Glutathione metabolism_Homo sapiens_hsa004800.63546883
60Cell cycle_Homo sapiens_hsa041100.63372868
61Fanconi anemia pathway_Homo sapiens_hsa034600.62254436
62Regulation of autophagy_Homo sapiens_hsa041400.58968242
63Synaptic vesicle cycle_Homo sapiens_hsa047210.58248741
64Cysteine and methionine metabolism_Homo sapiens_hsa002700.57207800
65Pentose phosphate pathway_Homo sapiens_hsa000300.56487384
66Propanoate metabolism_Homo sapiens_hsa006400.53449988
67Shigellosis_Homo sapiens_hsa051310.50959422
68Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.49802280
69Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.46936646
70Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.46633384
71Sulfur metabolism_Homo sapiens_hsa009200.45046711
72Alcoholism_Homo sapiens_hsa050340.43606345
73Allograft rejection_Homo sapiens_hsa053300.42033646
74Maturity onset diabetes of the young_Homo sapiens_hsa049500.41021125
75Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.40890723
76Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.39605642
77Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.39185565
78Linoleic acid metabolism_Homo sapiens_hsa005910.39037955
79Serotonergic synapse_Homo sapiens_hsa047260.38877417
80Rheumatoid arthritis_Homo sapiens_hsa053230.38169460
81Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.37884366
82Butanoate metabolism_Homo sapiens_hsa006500.37235289
83beta-Alanine metabolism_Homo sapiens_hsa004100.37076469
84Autoimmune thyroid disease_Homo sapiens_hsa053200.36092459
85mRNA surveillance pathway_Homo sapiens_hsa030150.34947420
86Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.32861063
87Fatty acid degradation_Homo sapiens_hsa000710.30776160
88Fatty acid metabolism_Homo sapiens_hsa012120.30293445
89Endocytosis_Homo sapiens_hsa041440.29868426
90RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.29474275
91alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.29332126
92Arginine and proline metabolism_Homo sapiens_hsa003300.29244643
93Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.27869780
94Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.26077555
95Biosynthesis of amino acids_Homo sapiens_hsa012300.25431897
96Fat digestion and absorption_Homo sapiens_hsa049750.24603251
97Tyrosine metabolism_Homo sapiens_hsa003500.24262616
98Histidine metabolism_Homo sapiens_hsa003400.24017378
99Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.23627499
100Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.23508137
101Oocyte meiosis_Homo sapiens_hsa041140.22414146
102Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.21679424
103Phagosome_Homo sapiens_hsa041450.20215040
104Salmonella infection_Homo sapiens_hsa051320.19885250
105Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.19352173
106Carbon metabolism_Homo sapiens_hsa012000.17990452
107Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.17247464
108Drug metabolism - other enzymes_Homo sapiens_hsa009830.17176650
109Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.15531143
110Phototransduction_Homo sapiens_hsa047440.15388200
111Peroxisome_Homo sapiens_hsa041460.14322110
112Thyroid cancer_Homo sapiens_hsa052160.12596646
113Antigen processing and presentation_Homo sapiens_hsa046120.11734152
114Dopaminergic synapse_Homo sapiens_hsa047280.11495728
115Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.11133298
116Tryptophan metabolism_Homo sapiens_hsa003800.11028815
117Notch signaling pathway_Homo sapiens_hsa043300.10244570
118Fructose and mannose metabolism_Homo sapiens_hsa000510.09072416
119Axon guidance_Homo sapiens_hsa043600.08600597
120Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.08310038
121Vitamin B6 metabolism_Homo sapiens_hsa007500.08287673
122Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.07362298
123Pertussis_Homo sapiens_hsa051330.06289542
124Platelet activation_Homo sapiens_hsa046110.06232715
125Apoptosis_Homo sapiens_hsa042100.06061621

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