

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.34791505 |
| 2 | ATP synthesis coupled proton transport (GO:0015986) | 5.34791505 |
| 3 | tachykinin receptor signaling pathway (GO:0007217) | 5.23236418 |
| 4 | adaptation of signaling pathway (GO:0023058) | 5.05235363 |
| 5 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.79972054 |
| 6 | viral transcription (GO:0019083) | 4.58018008 |
| 7 | positive regulation of mitochondrial fission (GO:0090141) | 4.44408497 |
| 8 | dopamine biosynthetic process (GO:0042416) | 4.43021625 |
| 9 | glyoxylate metabolic process (GO:0046487) | 4.42196659 |
| 10 | translational termination (GO:0006415) | 4.38235946 |
| 11 | protein localization to cilium (GO:0061512) | 4.24726877 |
| 12 | heterochromatin organization (GO:0070828) | 4.18076062 |
| 13 | regulation of cilium movement (GO:0003352) | 4.06483897 |
| 14 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.92828417 |
| 15 | gamma-aminobutyric acid transport (GO:0015812) | 3.87368322 |
| 16 | nonmotile primary cilium assembly (GO:0035058) | 3.82887899 |
| 17 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.82114744 |
| 18 | cotranslational protein targeting to membrane (GO:0006613) | 3.80691124 |
| 19 | protein targeting to ER (GO:0045047) | 3.74756528 |
| 20 | detection of temperature stimulus (GO:0016048) | 3.72943805 |
| 21 | behavioral response to nicotine (GO:0035095) | 3.68802861 |
| 22 | translational elongation (GO:0006414) | 3.64287705 |
| 23 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.62035073 |
| 24 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.59632564 |
| 25 | auditory receptor cell differentiation (GO:0042491) | 3.53629725 |
| 26 | respiratory electron transport chain (GO:0022904) | 3.53079463 |
| 27 | ribosomal small subunit assembly (GO:0000028) | 3.52578285 |
| 28 | electron transport chain (GO:0022900) | 3.52531372 |
| 29 | substrate-independent telencephalic tangential migration (GO:0021826) | 3.49453148 |
| 30 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 3.49453148 |
| 31 | histone H2A monoubiquitination (GO:0035518) | 3.49159834 |
| 32 | ribosomal small subunit biogenesis (GO:0042274) | 3.48480862 |
| 33 | protein localization to endoplasmic reticulum (GO:0070972) | 3.48015028 |
| 34 | dopamine transport (GO:0015872) | 3.39010630 |
| 35 | catechol-containing compound biosynthetic process (GO:0009713) | 3.37945235 |
| 36 | catecholamine biosynthetic process (GO:0042423) | 3.37945235 |
| 37 | viral life cycle (GO:0019058) | 3.34454353 |
| 38 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 3.33422493 |
| 39 | detection of temperature stimulus involved in sensory perception (GO:0050961) | 3.31842208 |
| 40 | detection of temperature stimulus involved in sensory perception of pain (GO:0050965) | 3.31842208 |
| 41 | cellular protein complex disassembly (GO:0043624) | 3.31676974 |
| 42 | serine family amino acid catabolic process (GO:0009071) | 3.28785270 |
| 43 | transmission of nerve impulse (GO:0019226) | 3.22942981 |
| 44 | protein complex biogenesis (GO:0070271) | 3.21862333 |
| 45 | regulation of dopamine metabolic process (GO:0042053) | 3.16747631 |
| 46 | regulation of catecholamine metabolic process (GO:0042069) | 3.16747631 |
| 47 | cardiac right ventricle morphogenesis (GO:0003215) | 3.16067912 |
| 48 | protein-cofactor linkage (GO:0018065) | 3.14910635 |
| 49 | epithelial cilium movement (GO:0003351) | 3.14370440 |
| 50 | termination of RNA polymerase III transcription (GO:0006386) | 3.12911695 |
| 51 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.12911695 |
| 52 | receptor recycling (GO:0001881) | 3.12018897 |
| 53 | ATP biosynthetic process (GO:0006754) | 3.06692275 |
| 54 | somite development (GO:0061053) | 3.01893462 |
| 55 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.00350402 |
| 56 | neuronal action potential propagation (GO:0019227) | 2.97027916 |
| 57 | ovulation cycle (GO:0042698) | 2.93737720 |
| 58 | neuronal ion channel clustering (GO:0045161) | 2.92794898 |
| 59 | hydrogen ion transmembrane transport (GO:1902600) | 2.92311162 |
| 60 | organelle disassembly (GO:1903008) | 2.89937819 |
| 61 | histone H2A ubiquitination (GO:0033522) | 2.89658989 |
| 62 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.87033108 |
| 63 | parturition (GO:0007567) | 2.86073435 |
| 64 | regulation of mitochondrial fission (GO:0090140) | 2.84614447 |
| 65 | short-term memory (GO:0007614) | 2.81130933 |
| 66 | forebrain neuron differentiation (GO:0021879) | 2.79260348 |
| 67 | basic amino acid transport (GO:0015802) | 2.78273000 |
| 68 | protein polyglutamylation (GO:0018095) | 2.77464918 |
| 69 | protein localization to Golgi apparatus (GO:0034067) | 2.77032761 |
| 70 | maturation of SSU-rRNA (GO:0030490) | 2.75132107 |
| 71 | response to pheromone (GO:0019236) | 2.73552881 |
| 72 | protein complex disassembly (GO:0043241) | 2.73252208 |
| 73 | central nervous system myelination (GO:0022010) | 2.71858994 |
| 74 | axon ensheathment in central nervous system (GO:0032291) | 2.71858994 |
| 75 | intraciliary transport (GO:0042073) | 2.69306626 |
| 76 | somite rostral/caudal axis specification (GO:0032525) | 2.69294063 |
| 77 | translational initiation (GO:0006413) | 2.68653051 |
| 78 | ribosomal large subunit biogenesis (GO:0042273) | 2.67317805 |
| 79 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.66691594 |
| 80 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.66691594 |
| 81 | positive regulation of protein homooligomerization (GO:0032464) | 2.64166418 |
| 82 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.64061008 |
| 83 | cerebellar Purkinje cell differentiation (GO:0021702) | 2.63461248 |
| 84 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.63226624 |
| 85 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.63194229 |
| 86 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.63194229 |
| 87 | macromolecular complex disassembly (GO:0032984) | 2.63098688 |
| 88 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.61420739 |
| 89 | positive regulation of gastrulation (GO:2000543) | 2.61137219 |
| 90 | axonal fasciculation (GO:0007413) | 2.60722973 |
| 91 | synaptic transmission, glutamatergic (GO:0035249) | 2.59917199 |
| 92 | regulation of female receptivity (GO:0045924) | 2.57040854 |
| 93 | serotonin metabolic process (GO:0042428) | 2.54071609 |
| 94 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.53072885 |
| 95 | NADH dehydrogenase complex assembly (GO:0010257) | 2.53072885 |
| 96 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.53072885 |
| 97 | regulation of feeding behavior (GO:0060259) | 2.52486294 |
| 98 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.50814261 |
| 99 | regulation of mitochondrial translation (GO:0070129) | 2.49083589 |
| 100 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 2.48687476 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.76682791 |
| 2 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.99077108 |
| 3 | VDR_22108803_ChIP-Seq_LS180_Human | 2.90020889 |
| 4 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.83177720 |
| 5 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.64122850 |
| 6 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.49438507 |
| 7 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.47667225 |
| 8 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.43052100 |
| 9 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.40850011 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.32928241 |
| 11 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.30498740 |
| 12 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.29180693 |
| 13 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.22872907 |
| 14 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.20392303 |
| 15 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.17440554 |
| 16 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.16549124 |
| 17 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.13591650 |
| 18 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.13363034 |
| 19 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.12387881 |
| 20 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.96995677 |
| 21 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.93172763 |
| 22 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.92921687 |
| 23 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.89316442 |
| 24 | FUS_26573619_Chip-Seq_HEK293_Human | 1.88736454 |
| 25 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.87560488 |
| 26 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.85815763 |
| 27 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.84204905 |
| 28 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.84197787 |
| 29 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.82737745 |
| 30 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.82737745 |
| 31 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.79176483 |
| 32 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.76226620 |
| 33 | EWS_26573619_Chip-Seq_HEK293_Human | 1.75968221 |
| 34 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.73696665 |
| 35 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.71743946 |
| 36 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.69301924 |
| 37 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.68783867 |
| 38 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.59354071 |
| 39 | P300_19829295_ChIP-Seq_ESCs_Human | 1.57164544 |
| 40 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.56842399 |
| 41 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.54159887 |
| 42 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.51538622 |
| 43 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.51441840 |
| 44 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.50812812 |
| 45 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.49567582 |
| 46 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.48576426 |
| 47 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.47314246 |
| 48 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.44892492 |
| 49 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.43879045 |
| 50 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.43042865 |
| 51 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.40987317 |
| 52 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.39376246 |
| 53 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.38627884 |
| 54 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.33435031 |
| 55 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.33435031 |
| 56 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.32281420 |
| 57 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.31235168 |
| 58 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.29438409 |
| 59 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.25267562 |
| 60 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.22224016 |
| 61 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.21235813 |
| 62 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.19200211 |
| 63 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.17429688 |
| 64 | AR_25329375_ChIP-Seq_VCAP_Human | 1.17304570 |
| 65 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.14023884 |
| 66 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.14018983 |
| 67 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.13428867 |
| 68 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.13221869 |
| 69 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.11014857 |
| 70 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.10398272 |
| 71 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 1.07476537 |
| 72 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 1.07027332 |
| 73 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.06496760 |
| 74 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.04656369 |
| 75 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.01725283 |
| 76 | NCOR_22424771_ChIP-Seq_293T_Human | 1.01395574 |
| 77 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.00835495 |
| 78 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.00652750 |
| 79 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.98835294 |
| 80 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 0.98403100 |
| 81 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.97529746 |
| 82 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.97529746 |
| 83 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.97144038 |
| 84 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.97130068 |
| 85 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 0.97034796 |
| 86 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.95862081 |
| 87 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 0.95782115 |
| 88 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.94898731 |
| 89 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.94599033 |
| 90 | STAT3_23295773_ChIP-Seq_U87_Human | 0.94419780 |
| 91 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 0.93932509 |
| 92 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.93758515 |
| 93 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 0.93739026 |
| 94 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.93000828 |
| 95 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.91948492 |
| 96 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.91688108 |
| 97 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.91282728 |
| 98 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.90932674 |
| 99 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.90158909 |
| 100 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.90008731 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005423_abnormal_somatic_nervous | 3.90569442 |
| 2 | MP0004858_abnormal_nervous_system | 3.07018863 |
| 3 | MP0004145_abnormal_muscle_electrophysio | 3.03666132 |
| 4 | MP0009379_abnormal_foot_pigmentation | 2.93543574 |
| 5 | MP0003787_abnormal_imprinting | 2.79861855 |
| 6 | MP0002736_abnormal_nociception_after | 2.59143496 |
| 7 | MP0003890_abnormal_embryonic-extraembry | 2.56296488 |
| 8 | MP0001968_abnormal_touch/_nociception | 2.54332657 |
| 9 | MP0004142_abnormal_muscle_tone | 2.44762327 |
| 10 | MP0003136_yellow_coat_color | 2.40373542 |
| 11 | MP0004885_abnormal_endolymph | 2.40247791 |
| 12 | MP0003011_delayed_dark_adaptation | 2.37981582 |
| 13 | MP0003880_abnormal_central_pattern | 2.27010527 |
| 14 | MP0006292_abnormal_olfactory_placode | 2.20842350 |
| 15 | MP0001440_abnormal_grooming_behavior | 2.17929986 |
| 16 | MP0000778_abnormal_nervous_system | 2.06577097 |
| 17 | MP0002272_abnormal_nervous_system | 2.00381374 |
| 18 | MP0002184_abnormal_innervation | 1.92976743 |
| 19 | MP0009745_abnormal_behavioral_response | 1.88228238 |
| 20 | MP0003121_genomic_imprinting | 1.83842021 |
| 21 | MP0003122_maternal_imprinting | 1.79700844 |
| 22 | MP0002063_abnormal_learning/memory/cond | 1.71674532 |
| 23 | MP0001727_abnormal_embryo_implantation | 1.70101266 |
| 24 | MP0000569_abnormal_digit_pigmentation | 1.69423145 |
| 25 | MP0002572_abnormal_emotion/affect_behav | 1.68090947 |
| 26 | MP0005551_abnormal_eye_electrophysiolog | 1.66505986 |
| 27 | MP0001905_abnormal_dopamine_level | 1.64338551 |
| 28 | MP0003878_abnormal_ear_physiology | 1.60216611 |
| 29 | MP0005377_hearing/vestibular/ear_phenot | 1.60216611 |
| 30 | MP0004742_abnormal_vestibular_system | 1.58451293 |
| 31 | MP0002938_white_spotting | 1.54171888 |
| 32 | MP0001485_abnormal_pinna_reflex | 1.53054811 |
| 33 | MP0002163_abnormal_gland_morphology | 1.50700746 |
| 34 | MP0005084_abnormal_gallbladder_morpholo | 1.49186407 |
| 35 | MP0000372_irregular_coat_pigmentation | 1.48426731 |
| 36 | MP0003123_paternal_imprinting | 1.48079170 |
| 37 | MP0002160_abnormal_reproductive_system | 1.47650779 |
| 38 | MP0009046_muscle_twitch | 1.46780928 |
| 39 | MP0001293_anophthalmia | 1.42592155 |
| 40 | MP0002752_abnormal_somatic_nervous | 1.41506386 |
| 41 | MP0002557_abnormal_social/conspecific_i | 1.40985213 |
| 42 | MP0000955_abnormal_spinal_cord | 1.40964541 |
| 43 | MP0006276_abnormal_autonomic_nervous | 1.40697072 |
| 44 | MP0001529_abnormal_vocalization | 1.40500982 |
| 45 | MP0003635_abnormal_synaptic_transmissio | 1.40492482 |
| 46 | MP0001502_abnormal_circadian_rhythm | 1.35201108 |
| 47 | MP0004133_heterotaxia | 1.33598654 |
| 48 | MP0002234_abnormal_pharynx_morphology | 1.32683915 |
| 49 | MP0008872_abnormal_physiological_respon | 1.29966388 |
| 50 | MP0008789_abnormal_olfactory_epithelium | 1.26658218 |
| 51 | MP0006072_abnormal_retinal_apoptosis | 1.20458804 |
| 52 | MP0002067_abnormal_sensory_capabilities | 1.20445361 |
| 53 | MP0002928_abnormal_bile_duct | 1.19619309 |
| 54 | MP0003567_abnormal_fetal_cardiomyocyte | 1.15686508 |
| 55 | MP0002653_abnormal_ependyma_morphology | 1.14530702 |
| 56 | MP0002882_abnormal_neuron_morphology | 1.13796854 |
| 57 | MP0000631_abnormal_neuroendocrine_gland | 1.10701063 |
| 58 | MP0005195_abnormal_posterior_eye | 1.10678720 |
| 59 | MP0000427_abnormal_hair_cycle | 1.09275512 |
| 60 | MP0005379_endocrine/exocrine_gland_phen | 1.09020138 |
| 61 | MP0002733_abnormal_thermal_nociception | 1.08905019 |
| 62 | MP0006035_abnormal_mitochondrial_morpho | 1.06291099 |
| 63 | MP0003119_abnormal_digestive_system | 1.04836421 |
| 64 | MP0008875_abnormal_xenobiotic_pharmacok | 1.01109287 |
| 65 | MP0003942_abnormal_urinary_system | 1.01103084 |
| 66 | MP0000026_abnormal_inner_ear | 0.98682477 |
| 67 | MP0005253_abnormal_eye_physiology | 0.98292446 |
| 68 | MP0001486_abnormal_startle_reflex | 0.98137017 |
| 69 | MP0001986_abnormal_taste_sensitivity | 0.95690212 |
| 70 | MP0002064_seizures | 0.95013550 |
| 71 | MP0005389_reproductive_system_phenotype | 0.94177376 |
| 72 | MP0003861_abnormal_nervous_system | 0.92305465 |
| 73 | MP0002751_abnormal_autonomic_nervous | 0.91625965 |
| 74 | MP0004811_abnormal_neuron_physiology | 0.91587365 |
| 75 | MP0002102_abnormal_ear_morphology | 0.91137398 |
| 76 | MP0009053_abnormal_anal_canal | 0.91068562 |
| 77 | MP0009697_abnormal_copulation | 0.90075488 |
| 78 | MP0002229_neurodegeneration | 0.89833275 |
| 79 | MP0001286_abnormal_eye_development | 0.85935590 |
| 80 | MP0002152_abnormal_brain_morphology | 0.85861429 |
| 81 | MP0005499_abnormal_olfactory_system | 0.84861209 |
| 82 | MP0005394_taste/olfaction_phenotype | 0.84861209 |
| 83 | MP0002210_abnormal_sex_determination | 0.83085579 |
| 84 | MP0001984_abnormal_olfaction | 0.83020394 |
| 85 | MP0002282_abnormal_trachea_morphology | 0.82528992 |
| 86 | MP0003937_abnormal_limbs/digits/tail_de | 0.80391102 |
| 87 | MP0002090_abnormal_vision | 0.79900668 |
| 88 | MP0003186_abnormal_redox_activity | 0.79893980 |
| 89 | MP0001919_abnormal_reproductive_system | 0.79808201 |
| 90 | MP0005391_vision/eye_phenotype | 0.79736986 |
| 91 | MP0005410_abnormal_fertilization | 0.79260032 |
| 92 | MP0005386_behavior/neurological_phenoty | 0.79119148 |
| 93 | MP0004924_abnormal_behavior | 0.79119148 |
| 94 | MP0002734_abnormal_mechanical_nocicepti | 0.78650652 |
| 95 | MP0002876_abnormal_thyroid_physiology | 0.78629825 |
| 96 | MP0008058_abnormal_DNA_repair | 0.78374123 |
| 97 | MP0001348_abnormal_lacrimal_gland | 0.76834153 |
| 98 | MP0005187_abnormal_penis_morphology | 0.75781570 |
| 99 | MP0006036_abnormal_mitochondrial_physio | 0.75323474 |
| 100 | MP0005646_abnormal_pituitary_gland | 0.75264481 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Chronic hepatic failure (HP:0100626) | 4.33713990 |
| 2 | Abnormality of midbrain morphology (HP:0002418) | 4.14965572 |
| 3 | Molar tooth sign on MRI (HP:0002419) | 4.14965572 |
| 4 | Diastasis recti (HP:0001540) | 3.98648822 |
| 5 | Reticulocytopenia (HP:0001896) | 3.90389969 |
| 6 | Medial flaring of the eyebrow (HP:0010747) | 3.60716305 |
| 7 | Pancreatic fibrosis (HP:0100732) | 3.57955684 |
| 8 | Acute necrotizing encephalopathy (HP:0006965) | 3.43871497 |
| 9 | Pendular nystagmus (HP:0012043) | 3.37308924 |
| 10 | Poor coordination (HP:0002370) | 3.36213236 |
| 11 | Abnormality of the corticospinal tract (HP:0002492) | 3.35886923 |
| 12 | Nephronophthisis (HP:0000090) | 3.35822955 |
| 13 | Gait imbalance (HP:0002141) | 3.32977175 |
| 14 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.27692066 |
| 15 | Congenital primary aphakia (HP:0007707) | 3.18473023 |
| 16 | Pancreatic cysts (HP:0001737) | 3.13334258 |
| 17 | Sclerocornea (HP:0000647) | 3.11977257 |
| 18 | Nephrogenic diabetes insipidus (HP:0009806) | 3.02009852 |
| 19 | Abnormality of the labia minora (HP:0012880) | 3.01599169 |
| 20 | Increased hepatocellular lipid droplets (HP:0006565) | 3.00302321 |
| 21 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.99364822 |
| 22 | Mitochondrial inheritance (HP:0001427) | 2.98735961 |
| 23 | Aplastic anemia (HP:0001915) | 2.98310806 |
| 24 | Abnormality of the renal medulla (HP:0100957) | 2.97093745 |
| 25 | Abnormal hair whorl (HP:0010721) | 2.94652266 |
| 26 | Colon cancer (HP:0003003) | 2.93472712 |
| 27 | Acute encephalopathy (HP:0006846) | 2.92856122 |
| 28 | True hermaphroditism (HP:0010459) | 2.87934320 |
| 29 | Abnormality of renal resorption (HP:0011038) | 2.84533833 |
| 30 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.83267339 |
| 31 | Progressive macrocephaly (HP:0004481) | 2.82759905 |
| 32 | Abnormal number of erythroid precursors (HP:0012131) | 2.75936946 |
| 33 | Hypogonadotrophic hypogonadism (HP:0000044) | 2.75244936 |
| 34 | Renal Fanconi syndrome (HP:0001994) | 2.64556057 |
| 35 | Congenital stationary night blindness (HP:0007642) | 2.55146813 |
| 36 | Chromsome breakage (HP:0040012) | 2.49854024 |
| 37 | Genital tract atresia (HP:0001827) | 2.49576956 |
| 38 | Lipid accumulation in hepatocytes (HP:0006561) | 2.48962052 |
| 39 | Vaginal atresia (HP:0000148) | 2.47452167 |
| 40 | Specific learning disability (HP:0001328) | 2.46575074 |
| 41 | Increased CSF lactate (HP:0002490) | 2.41120608 |
| 42 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.32104722 |
| 43 | Hepatic necrosis (HP:0002605) | 2.30586623 |
| 44 | Hepatocellular necrosis (HP:0001404) | 2.30335661 |
| 45 | Metaphyseal dysplasia (HP:0100255) | 2.30288762 |
| 46 | Chorioretinal atrophy (HP:0000533) | 2.29372346 |
| 47 | Spastic tetraparesis (HP:0001285) | 2.27045094 |
| 48 | Abnormality of the nasal septum (HP:0000419) | 2.24643879 |
| 49 | Osteomalacia (HP:0002749) | 2.22570126 |
| 50 | Respiratory difficulties (HP:0002880) | 2.20729626 |
| 51 | Decreased testicular size (HP:0008734) | 2.19551783 |
| 52 | Cerebral edema (HP:0002181) | 2.19454764 |
| 53 | Abolished electroretinogram (ERG) (HP:0000550) | 2.16905565 |
| 54 | Poor suck (HP:0002033) | 2.15650105 |
| 55 | Polyphagia (HP:0002591) | 2.12915410 |
| 56 | Macrocytic anemia (HP:0001972) | 2.12624521 |
| 57 | Impulsivity (HP:0100710) | 2.11408230 |
| 58 | Sleep apnea (HP:0010535) | 2.07345383 |
| 59 | Postaxial foot polydactyly (HP:0001830) | 2.02629494 |
| 60 | Neoplasm of the adrenal cortex (HP:0100641) | 2.01641789 |
| 61 | Abnormal urine phosphate concentration (HP:0012599) | 2.01338272 |
| 62 | Hyperphosphaturia (HP:0003109) | 2.01100932 |
| 63 | Abnormality of the renal collecting system (HP:0004742) | 1.99157535 |
| 64 | Meckel diverticulum (HP:0002245) | 1.98193296 |
| 65 | Optic disc pallor (HP:0000543) | 1.97326548 |
| 66 | Exertional dyspnea (HP:0002875) | 1.96931279 |
| 67 | Morphological abnormality of the pyramidal tract (HP:0002062) | 1.96501737 |
| 68 | Amyotrophic lateral sclerosis (HP:0007354) | 1.94245765 |
| 69 | Abnormality of the lower motor neuron (HP:0002366) | 1.94097224 |
| 70 | Cystic liver disease (HP:0006706) | 1.93629949 |
| 71 | Duplicated collecting system (HP:0000081) | 1.92070489 |
| 72 | Pallor (HP:0000980) | 1.91469163 |
| 73 | Broad foot (HP:0001769) | 1.90504991 |
| 74 | Abnormality of the renal cortex (HP:0011035) | 1.90158095 |
| 75 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.88408719 |
| 76 | Proximal tubulopathy (HP:0000114) | 1.88111516 |
| 77 | Drooling (HP:0002307) | 1.86547339 |
| 78 | Anophthalmia (HP:0000528) | 1.85175973 |
| 79 | Abnormality of the ileum (HP:0001549) | 1.83965119 |
| 80 | Hepatoblastoma (HP:0002884) | 1.83243471 |
| 81 | Hyperglycinemia (HP:0002154) | 1.83235995 |
| 82 | Aganglionic megacolon (HP:0002251) | 1.81575285 |
| 83 | Septo-optic dysplasia (HP:0100842) | 1.80966830 |
| 84 | Abnormal pancreas size (HP:0012094) | 1.80596894 |
| 85 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.79269953 |
| 86 | Postaxial hand polydactyly (HP:0001162) | 1.79051869 |
| 87 | Abnormality of urine glucose concentration (HP:0011016) | 1.77254367 |
| 88 | Glycosuria (HP:0003076) | 1.77254367 |
| 89 | Anosmia (HP:0000458) | 1.77051008 |
| 90 | Congenital, generalized hypertrichosis (HP:0004540) | 1.75390007 |
| 91 | Anencephaly (HP:0002323) | 1.75068491 |
| 92 | Abnormality of the aortic arch (HP:0012303) | 1.74993225 |
| 93 | Male pseudohermaphroditism (HP:0000037) | 1.72998890 |
| 94 | Progressive cerebellar ataxia (HP:0002073) | 1.72050604 |
| 95 | Genetic anticipation (HP:0003743) | 1.71563354 |
| 96 | Clubbing of toes (HP:0100760) | 1.70954803 |
| 97 | Aplasia/Hypoplasia of the lens (HP:0008063) | 1.68459634 |
| 98 | Abnormality of lateral ventricle (HP:0030047) | 1.67443426 |
| 99 | Absent thumb (HP:0009777) | 1.66890327 |
| 100 | Excessive salivation (HP:0003781) | 1.66738657 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DYRK3 | 3.29992440 |
| 2 | MAP3K4 | 2.89685257 |
| 3 | TAF1 | 2.56582006 |
| 4 | MARK1 | 2.42862973 |
| 5 | GRK1 | 2.37720892 |
| 6 | NME1 | 2.36682641 |
| 7 | VRK2 | 2.33400704 |
| 8 | EIF2AK1 | 2.14203526 |
| 9 | DYRK2 | 2.11482838 |
| 10 | ADRBK2 | 1.98878890 |
| 11 | NTRK2 | 1.90967962 |
| 12 | WNK3 | 1.82535614 |
| 13 | PRKCG | 1.79612199 |
| 14 | PNCK | 1.77275589 |
| 15 | VRK1 | 1.75633050 |
| 16 | FRK | 1.74876655 |
| 17 | TNIK | 1.73715350 |
| 18 | NUAK1 | 1.73500873 |
| 19 | BMPR1B | 1.70512575 |
| 20 | MAPK15 | 1.68982008 |
| 21 | MAP3K10 | 1.67923814 |
| 22 | TLK1 | 1.67104831 |
| 23 | SGK2 | 1.65852095 |
| 24 | MAPK13 | 1.62161302 |
| 25 | SGK223 | 1.56655391 |
| 26 | SGK494 | 1.56655391 |
| 27 | STK24 | 1.46573767 |
| 28 | MKNK2 | 1.46173647 |
| 29 | CASK | 1.41462641 |
| 30 | NLK | 1.40544268 |
| 31 | WNK4 | 1.36330201 |
| 32 | STK39 | 1.33032316 |
| 33 | RPS6KA2 | 1.32535827 |
| 34 | MINK1 | 1.32495601 |
| 35 | NTRK3 | 1.30920673 |
| 36 | BCKDK | 1.28861673 |
| 37 | MAP2K7 | 1.22013529 |
| 38 | EPHB2 | 1.17278969 |
| 39 | EPHA4 | 1.16743801 |
| 40 | DMPK | 1.12079467 |
| 41 | ZAK | 1.11275169 |
| 42 | PINK1 | 1.09260778 |
| 43 | CDC7 | 1.04355271 |
| 44 | INSRR | 1.03222921 |
| 45 | PAK3 | 1.01508328 |
| 46 | DYRK1A | 1.00535524 |
| 47 | PRKCQ | 0.95581747 |
| 48 | BRD4 | 0.91912277 |
| 49 | TIE1 | 0.91347941 |
| 50 | RPS6KA6 | 0.90758689 |
| 51 | DAPK2 | 0.88220949 |
| 52 | OXSR1 | 0.87885757 |
| 53 | EIF2AK3 | 0.82515932 |
| 54 | CSNK1G2 | 0.82258805 |
| 55 | PLK3 | 0.81913081 |
| 56 | MAP2K4 | 0.79252426 |
| 57 | STK3 | 0.78991218 |
| 58 | MAP4K2 | 0.78952468 |
| 59 | TGFBR1 | 0.76994861 |
| 60 | PLK4 | 0.76320137 |
| 61 | GRK5 | 0.76296579 |
| 62 | LATS2 | 0.73712787 |
| 63 | SGK3 | 0.69341644 |
| 64 | PRKCZ | 0.65054535 |
| 65 | RPS6KC1 | 0.64812333 |
| 66 | RPS6KL1 | 0.64812333 |
| 67 | MAPKAPK3 | 0.64432677 |
| 68 | ACVR1B | 0.63571892 |
| 69 | PBK | 0.63432266 |
| 70 | TAOK3 | 0.62369552 |
| 71 | CAMK4 | 0.62230505 |
| 72 | PASK | 0.61913235 |
| 73 | CAMK2A | 0.61418599 |
| 74 | ABL2 | 0.59837342 |
| 75 | TSSK6 | 0.59138458 |
| 76 | MKNK1 | 0.58838884 |
| 77 | ADRBK1 | 0.58560105 |
| 78 | SGK1 | 0.58447278 |
| 79 | PRKCE | 0.57927961 |
| 80 | STK38L | 0.57123083 |
| 81 | PLK1 | 0.56682518 |
| 82 | MARK2 | 0.55148757 |
| 83 | IRAK2 | 0.53828811 |
| 84 | MAP3K12 | 0.53483210 |
| 85 | PRKCD | 0.52079373 |
| 86 | PRKACA | 0.51542816 |
| 87 | RPS6KA5 | 0.51195298 |
| 88 | MAPKAPK5 | 0.51140695 |
| 89 | PLK2 | 0.50775095 |
| 90 | STK11 | 0.50558718 |
| 91 | PRKG1 | 0.49342218 |
| 92 | CHUK | 0.49001866 |
| 93 | PTK2B | 0.47364087 |
| 94 | ERBB2 | 0.46202594 |
| 95 | NEK9 | 0.45756065 |
| 96 | MAP3K11 | 0.45693156 |
| 97 | RPS6KA1 | 0.44752800 |
| 98 | AURKA | 0.41606672 |
| 99 | TTK | 0.40733344 |
| 100 | TEC | 0.38720455 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.62850331 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.43965538 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 4.02101634 |
| 4 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.92934123 |
| 5 | Sulfur relay system_Homo sapiens_hsa04122 | 2.82164540 |
| 6 | Huntingtons disease_Homo sapiens_hsa05016 | 2.79925214 |
| 7 | Alzheimers disease_Homo sapiens_hsa05010 | 2.77117526 |
| 8 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 2.66696130 |
| 9 | RNA polymerase_Homo sapiens_hsa03020 | 2.58226626 |
| 10 | Protein export_Homo sapiens_hsa03060 | 2.47351832 |
| 11 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.19726159 |
| 12 | Nicotine addiction_Homo sapiens_hsa05033 | 1.90519637 |
| 13 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.83088206 |
| 14 | Phototransduction_Homo sapiens_hsa04744 | 1.71991416 |
| 15 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.64124888 |
| 16 | Homologous recombination_Homo sapiens_hsa03440 | 1.53741592 |
| 17 | Morphine addiction_Homo sapiens_hsa05032 | 1.49726618 |
| 18 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.45242267 |
| 19 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.41927611 |
| 20 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.37329095 |
| 21 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.27530137 |
| 22 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.27119571 |
| 23 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.25518439 |
| 24 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.23642509 |
| 25 | Circadian entrainment_Homo sapiens_hsa04713 | 1.22044691 |
| 26 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.19860963 |
| 27 | Proteasome_Homo sapiens_hsa03050 | 1.19477710 |
| 28 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.18882473 |
| 29 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.17537841 |
| 30 | Purine metabolism_Homo sapiens_hsa00230 | 1.11632592 |
| 31 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.10325510 |
| 32 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.05779237 |
| 33 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.05180812 |
| 34 | GABAergic synapse_Homo sapiens_hsa04727 | 1.03189445 |
| 35 | Peroxisome_Homo sapiens_hsa04146 | 0.99607301 |
| 36 | Basal transcription factors_Homo sapiens_hsa03022 | 0.98060152 |
| 37 | Cocaine addiction_Homo sapiens_hsa05030 | 0.97856852 |
| 38 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.96909403 |
| 39 | Axon guidance_Homo sapiens_hsa04360 | 0.95737814 |
| 40 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.94924584 |
| 41 | Renin secretion_Homo sapiens_hsa04924 | 0.94542592 |
| 42 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.93479882 |
| 43 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.91030732 |
| 44 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.90530516 |
| 45 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.88901299 |
| 46 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.88623781 |
| 47 | Taste transduction_Homo sapiens_hsa04742 | 0.85647437 |
| 48 | Long-term depression_Homo sapiens_hsa04730 | 0.85314041 |
| 49 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.82767852 |
| 50 | Olfactory transduction_Homo sapiens_hsa04740 | 0.82657673 |
| 51 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.82243828 |
| 52 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.81888261 |
| 53 | Base excision repair_Homo sapiens_hsa03410 | 0.81018755 |
| 54 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.79809936 |
| 55 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.78067640 |
| 56 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.75390864 |
| 57 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.74260929 |
| 58 | Asthma_Homo sapiens_hsa05310 | 0.72098497 |
| 59 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.70641882 |
| 60 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.67070956 |
| 61 | Retinol metabolism_Homo sapiens_hsa00830 | 0.66925393 |
| 62 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.66461198 |
| 63 | Insulin secretion_Homo sapiens_hsa04911 | 0.66127647 |
| 64 | Alcoholism_Homo sapiens_hsa05034 | 0.65309810 |
| 65 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.64563852 |
| 66 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.63661522 |
| 67 | RNA degradation_Homo sapiens_hsa03018 | 0.59882070 |
| 68 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.58400605 |
| 69 | Metabolic pathways_Homo sapiens_hsa01100 | 0.58187150 |
| 70 | Long-term potentiation_Homo sapiens_hsa04720 | 0.56555776 |
| 71 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.56192177 |
| 72 | RNA transport_Homo sapiens_hsa03013 | 0.55979850 |
| 73 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.55625116 |
| 74 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.55449038 |
| 75 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.54324112 |
| 76 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.52672665 |
| 77 | DNA replication_Homo sapiens_hsa03030 | 0.52531731 |
| 78 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.51909003 |
| 79 | Mismatch repair_Homo sapiens_hsa03430 | 0.50063656 |
| 80 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.47972308 |
| 81 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.46434331 |
| 82 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.44446252 |
| 83 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.44128291 |
| 84 | Mineral absorption_Homo sapiens_hsa04978 | 0.38267986 |
| 85 | Melanogenesis_Homo sapiens_hsa04916 | 0.38072310 |
| 86 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.37671895 |
| 87 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.36502062 |
| 88 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.33788885 |
| 89 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.32530859 |
| 90 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.32387728 |
| 91 | Spliceosome_Homo sapiens_hsa03040 | 0.32355750 |
| 92 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.30684052 |
| 93 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.30643926 |
| 94 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.30318837 |
| 95 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.30300467 |
| 96 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.28877609 |
| 97 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.28399233 |
| 98 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.28165066 |
| 99 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.27719541 |
| 100 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.25597254 |

