NUFIP2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)7.36339134
2nuclear pore organization (GO:0006999)6.75809951
3pore complex assembly (GO:0046931)5.79066224
4mitotic sister chromatid cohesion (GO:0007064)4.71728672
5regulation of RNA export from nucleus (GO:0046831)4.43016752
6regulation of histone H3-K9 methylation (GO:0051570)4.26853275
7regulation of gene silencing by RNA (GO:0060966)4.20693452
8regulation of posttranscriptional gene silencing (GO:0060147)4.20693452
9regulation of gene silencing by miRNA (GO:0060964)4.20693452
10negative regulation of histone methylation (GO:0031061)3.93270369
11regulation of histone H3-K27 methylation (GO:0061085)3.92762508
12pre-miRNA processing (GO:0031054)3.90938608
13positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.89286896
14positive regulation of mitotic sister chromatid separation (GO:1901970)3.89286896
15positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.89286896
16regulation of protein polyubiquitination (GO:1902914)3.82986160
17negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.82083893
18negative regulation of translation, ncRNA-mediated (GO:0040033)3.82083893
19regulation of translation, ncRNA-mediated (GO:0045974)3.82083893
20protein K6-linked ubiquitination (GO:0085020)3.69097517
21regulation of mitotic spindle organization (GO:0060236)3.60298793
22protein localization to kinetochore (GO:0034501)3.55475192
23regulation of nucleobase-containing compound transport (GO:0032239)3.54152697
24cytoplasmic mRNA processing body assembly (GO:0033962)3.52308317
25chromatin assembly (GO:0031497)3.48562516
26positive regulation of transcription from RNA polymerase III promoter (GO:0045945)3.46243761
27histone H2A monoubiquitination (GO:0035518)3.44340653
28positive regulation of SMAD protein import into nucleus (GO:0060391)3.40159435
29DNA unwinding involved in DNA replication (GO:0006268)3.40017289
30positive regulation of chromosome segregation (GO:0051984)3.37550181
31monoubiquitinated protein deubiquitination (GO:0035520)3.31216659
32mitotic nuclear envelope disassembly (GO:0007077)3.28885513
33regulation of spindle organization (GO:0090224)3.28851635
34regulation of DNA endoreduplication (GO:0032875)3.25397919
35NLS-bearing protein import into nucleus (GO:0006607)3.24242423
36histone lysine demethylation (GO:0070076)3.24102302
37response to UV-C (GO:0010225)3.23980455
38regulation of helicase activity (GO:0051095)3.23241211
39negative regulation of DNA repair (GO:0045738)3.22681574
40regulation of gene silencing (GO:0060968)3.21749574
41regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.19321192
42histone H3-K9 methylation (GO:0051567)3.17241657
43regulation of NFAT protein import into nucleus (GO:0051532)3.14645996
44nuclear envelope disassembly (GO:0051081)3.14618820
45membrane disassembly (GO:0030397)3.14618820
46DNA replication-dependent nucleosome assembly (GO:0006335)3.13896563
47DNA replication-dependent nucleosome organization (GO:0034723)3.13896563
48histone demethylation (GO:0016577)3.13067668
49mitotic chromosome condensation (GO:0007076)3.05694270
50histone H3-K9 modification (GO:0061647)3.03395301
51definitive hemopoiesis (GO:0060216)3.01942026
52phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.00397018
53glucocorticoid receptor signaling pathway (GO:0042921)2.99815626
54regulation of centriole replication (GO:0046599)2.97593461
55cellular protein complex localization (GO:0034629)2.96808216
56mitotic metaphase plate congression (GO:0007080)2.96576651
57regulation of DNA damage checkpoint (GO:2000001)2.95182254
58histone H3-K9 demethylation (GO:0033169)2.93007319
59regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.92997965
60positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.92997965
61negative regulation of chromatin modification (GO:1903309)2.92789031
62protein localization to chromosome, centromeric region (GO:0071459)2.92492141
63embryonic process involved in female pregnancy (GO:0060136)2.92448873
64embryonic camera-type eye morphogenesis (GO:0048596)2.91890821
65kinetochore organization (GO:0051383)2.90518963
66regulation of SMAD protein import into nucleus (GO:0060390)2.89839642
67negative regulation of DNA-dependent DNA replication (GO:2000104)2.88664652
68meiotic chromosome segregation (GO:0045132)2.88387768
69heterochromatin organization (GO:0070828)2.87824401
70sister chromatid cohesion (GO:0007062)2.84932281
71DNA geometric change (GO:0032392)2.84891855
72DNA duplex unwinding (GO:0032508)2.83580232
73positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.82487394
74regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.82487394
75dosage compensation (GO:0007549)2.82370701
76negative regulation of histone modification (GO:0031057)2.82332109
77paraxial mesoderm development (GO:0048339)2.81822703
78regulation of sister chromatid cohesion (GO:0007063)2.80463475
79peptidyl-threonine phosphorylation (GO:0018107)2.79824494
80microtubule cytoskeleton organization involved in mitosis (GO:1902850)2.78688443
81RNA stabilization (GO:0043489)2.78060228
82mRNA stabilization (GO:0048255)2.78060228
83peptidyl-threonine modification (GO:0018210)2.77995172
84spindle assembly involved in mitosis (GO:0090307)2.77870789
85corticosteroid receptor signaling pathway (GO:0031958)2.77738779
86metaphase plate congression (GO:0051310)2.76244706
87cellular response to ethanol (GO:0071361)2.75750956
88determination of adult lifespan (GO:0008340)2.74001024
89protein export from nucleus (GO:0006611)2.73257767
90muscle organ morphogenesis (GO:0048644)2.73053539
91sister chromatid segregation (GO:0000819)2.70545991
92histone H3-K4 trimethylation (GO:0080182)2.69560471
93positive regulation of protein import into nucleus, translocation (GO:0033160)2.68863735
94iron ion import (GO:0097286)2.67006101
95regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.66482969
96regulation of centrosome cycle (GO:0046605)2.64709996
97regulation of centrosome duplication (GO:0010824)2.63813864
98positive regulation of mRNA catabolic process (GO:0061014)2.63015093
99ribosome assembly (GO:0042255)2.60956739
100IMP biosynthetic process (GO:0006188)2.60632951
101histone H3-K36 demethylation (GO:0070544)2.60401553
102chromatin assembly or disassembly (GO:0006333)2.58016499
103interkinetic nuclear migration (GO:0022027)2.57490064
104protein dealkylation (GO:0008214)2.57407876
105protein demethylation (GO:0006482)2.57407876
106histone mRNA catabolic process (GO:0071044)2.56875844
107positive regulation of DNA-templated transcription, initiation (GO:2000144)2.56494201
108protein complex localization (GO:0031503)2.56315197
109focal adhesion assembly (GO:0048041)2.54525082
110cell-substrate adherens junction assembly (GO:0007045)2.54525082
111antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.54021359
112regulation of telomere maintenance via telomerase (GO:0032210)2.53589525
113attachment of spindle microtubules to kinetochore (GO:0008608)2.52403431
114nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.52007668
115regulation of chromatin silencing (GO:0031935)2.51873436
116mitotic sister chromatid segregation (GO:0000070)2.51812066
117adherens junction assembly (GO:0034333)2.51644586
118DNA synthesis involved in DNA repair (GO:0000731)2.49901307
119histone H3-K4 methylation (GO:0051568)2.48639513
120nucleus organization (GO:0006997)2.48447342
121embryonic eye morphogenesis (GO:0048048)2.47255046
122gene silencing by RNA (GO:0031047)2.47118508
123DNA conformation change (GO:0071103)2.45967885
124regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:00432.44898537
125histone H4-K12 acetylation (GO:0043983)2.44786320
126positive regulation of cell cycle checkpoint (GO:1901978)2.44267259
127trophectodermal cell differentiation (GO:0001829)2.43650974
128regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.42226394
129regulation of mitotic spindle checkpoint (GO:1903504)2.42226394
130histone phosphorylation (GO:0016572)2.40661103
131IMP metabolic process (GO:0046040)2.40486565
132regulation of mRNA stability (GO:0043488)2.40172013
133peptidyl-lysine trimethylation (GO:0018023)2.39132931
134regulation of chromatin binding (GO:0035561)2.38623756
1353-UTR-mediated mRNA stabilization (GO:0070935)2.38415535
136regulation of transforming growth factor beta2 production (GO:0032909)2.37383271
137hypotonic response (GO:0006971)2.37341154
138regulation of histone methylation (GO:0031060)2.36647491
139positive regulation of transcription initiation from RNA polymerase II promoter (GO:0060261)2.35042842
140nuclear envelope organization (GO:0006998)2.32661285
141protein K48-linked deubiquitination (GO:0071108)2.29138197
142peptidyl-threonine dephosphorylation (GO:0035970)2.29055743
143positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.28779495
144morphogenesis of an epithelial sheet (GO:0002011)2.25942524
145DNA topological change (GO:0006265)2.25395874
146response to epidermal growth factor (GO:0070849)2.24474404
147mRNA transport (GO:0051028)2.23618036
148chromosome condensation (GO:0030261)2.23226912
149regulation of necroptotic process (GO:0060544)2.23062044
150regulation of RNA stability (GO:0043487)2.21553354
151hippo signaling (GO:0035329)2.21214255
152peptidyl-lysine dimethylation (GO:0018027)2.20815561
153protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0042787)2.20572413

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.73293948
2FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse6.12247983
3SALL1_21062744_ChIP-ChIP_HESCs_Human4.65607271
4FOXM1_23109430_ChIP-Seq_U2OS_Human4.59490947
5EGR1_19374776_ChIP-ChIP_THP-1_Human3.40251553
6E2F4_17652178_ChIP-ChIP_JURKAT_Human3.39106839
7* KDM5B_21448134_ChIP-Seq_MESCs_Mouse3.24171538
8BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.82676450
9NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.54035257
10FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.38061147
11KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.20351759
12KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.20351759
13KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.20351759
14SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.16865848
15FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.09230666
16GATA1_22025678_ChIP-Seq_K562_Human1.89148957
17E2F1_21310950_ChIP-Seq_MCF-7_Human1.85691710
18TCF7_22412390_ChIP-Seq_EML_Mouse1.83501173
19SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.77625914
20* SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.77127109
21STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.68669970
22ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.66143536
23CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.65525569
24DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.60554582
25RBPJ_22232070_ChIP-Seq_NCS_Mouse1.58591097
26CLOCK_20551151_ChIP-Seq_293T_Human1.58546048
27* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.55555671
28HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.54163910
29* TCF3_18692474_ChIP-Seq_MESCs_Mouse1.52602068
30AR_21909140_ChIP-Seq_LNCAP_Human1.52318615
31SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.49648425
32ESR1_20079471_ChIP-ChIP_T-47D_Human1.49367718
33TP63_19390658_ChIP-ChIP_HaCaT_Human1.46830315
34MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.45975975
35KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.45000960
36* STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.42453422
37NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.42280277
38* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.38737847
39* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.38231878
40* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.35251598
41SCL_19346495_ChIP-Seq_HPC-7_Human1.34268809
42SMAD_19615063_ChIP-ChIP_OVARY_Human1.32710114
43* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.32650646
44ELK1_19687146_ChIP-ChIP_HELA_Human1.32242767
45FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.29872298
46ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.27483211
47SOX2_18555785_ChIP-Seq_MESCs_Mouse1.27365979
48* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.26896027
49* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.26534415
50POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.25695923
51VDR_21846776_ChIP-Seq_THP-1_Human1.25449922
52SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.25432785
53SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.25432785
54BRD4_25478319_ChIP-Seq_HGPS_Human1.24783997
55MYC_18555785_ChIP-Seq_MESCs_Mouse1.24432301
56ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.23638106
57* SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.21382708
58MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.18166677
59TP53_16413492_ChIP-PET_HCT116_Human1.17136795
60SOX9_24532713_ChIP-Seq_HFSC_Mouse1.16386521
61MYB_26560356_Chip-Seq_TH2_Human1.15961920
62PKCTHETA_26484144_Chip-Seq_BREAST_Human1.15727560
63CTNNB1_20460455_ChIP-Seq_HCT116_Human1.14948971
64TFEB_21752829_ChIP-Seq_HELA_Human1.14649558
65* TCF3_18692474_ChIP-Seq_MEFs_Mouse1.14203238
66SALL4_18804426_ChIP-ChIP_XEN_Mouse1.14144561
67* PU_27001747_Chip-Seq_BMDM_Mouse1.13836219
68CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.13717366
69* SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.12927710
70FOXO3_23340844_ChIP-Seq_DLD1_Human1.12275759
71EWS_26573619_Chip-Seq_HEK293_Human1.12274506
72MYC_19079543_ChIP-ChIP_MESCs_Mouse1.12236338
73STAT3_1855785_ChIP-Seq_MESCs_Mouse1.12000489
74SOX2_27498859_Chip-Seq_STOMACH_Mouse1.11936576
75HIF1A_21447827_ChIP-Seq_MCF-7_Human1.11810524
76TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.11410170
77NANOG_18555785_ChIP-Seq_MESCs_Mouse1.08900675
78NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.07594914
79FLI1_27457419_Chip-Seq_LIVER_Mouse1.07376056
80P300_27058665_Chip-Seq_ZR-75-30cells_Human1.05370925
81TCF4_18268006_ChIP-ChIP_LS174T_Human1.04410414
82FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.04305300
83AHR_22903824_ChIP-Seq_MCF-7_Human1.04214724
84UBF1/2_26484160_Chip-Seq_HMECs_Human1.02540311
85MAF_26560356_Chip-Seq_TH1_Human1.01953956
86WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.01276660
87KDM2B_26808549_Chip-Seq_SUP-B15_Human1.01219612
88KDM2B_26808549_Chip-Seq_DND41_Human1.01187076
89NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.00611998
90CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.00404403
91VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.00401285
92* NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.99528834
93Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.99412311
94ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.99332910
95RUNX_20019798_ChIP-Seq_JUKART_Human0.99058637
96TP63_17297297_ChIP-ChIP_HaCaT_Human0.97895568
97PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.97696994
98* POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.97614469
99* ZFP281_27345836_Chip-Seq_ESCs_Mouse0.97543422
100RUNX1_27514584_Chip-Seq_MCF-7_Human0.97423971
101* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.96975576
102* MYC_19030024_ChIP-ChIP_MESCs_Mouse0.96481460
103* VDR_24763502_ChIP-Seq_THP-1_Human0.96356457
104MYCN_18555785_ChIP-Seq_MESCs_Mouse0.96150684
105PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.96132218
106KDM2B_26808549_Chip-Seq_JURKAT_Human0.96110806
107TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.95790242
108MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.95350752
109POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.94984990
110STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.94056038
111IRF8_27001747_Chip-Seq_BMDM_Mouse0.94048333
112GATA6_25053715_ChIP-Seq_YYC3_Human0.92476775
113POU5F1_16153702_ChIP-ChIP_HESCs_Human0.92219214
114* PADI4_21655091_ChIP-ChIP_MCF-7_Human0.92208305
115FUS_26573619_Chip-Seq_HEK293_Human0.91371108
116* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.90320528
117RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.90005485
118ESR1_15608294_ChIP-ChIP_MCF-7_Human0.89584002
119NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.89573701
120WT1_19549856_ChIP-ChIP_CCG9911_Human0.89486936
121MYB_26560356_Chip-Seq_TH1_Human0.89066811
122FOXM1_26456572_ChIP-Seq_MCF-7_Human0.89050097
123* TCF3_18347094_ChIP-ChIP_MESCs_Mouse0.87895465
124FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.87494424
125FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.85696739
126PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.84669098
127ZFX_18555785_ChIP-Seq_MESCs_Mouse0.83184706
128POU3F2_20337985_ChIP-ChIP_501MEL_Human0.82244482
129MYC_22102868_ChIP-Seq_BL_Human0.81667122
130MYB_21317192_ChIP-Seq_ERMYB_Mouse0.81605260
131CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.81144470
132NOTCH1_21737748_ChIP-Seq_TLL_Human0.81078100
133PPAR_26484153_Chip-Seq_NCI-H1993_Human0.80978094
134EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.80963839
135* NANOG_18692474_ChIP-Seq_MESCs_Mouse0.80880763
136SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.79922493
137ZNF217_24962896_ChIP-Seq_MCF-7_Human0.78032230
138* POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.77095085
139PCGF2_27294783_Chip-Seq_NPCs_Mouse0.77032200
140SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.76813220
141* TBX3_20139965_ChIP-Seq_ESCs_Mouse0.76059048
142PCGF2_27294783_Chip-Seq_ESCs_Mouse0.76035234
143CHD1_26751641_Chip-Seq_LNCaP_Human0.75767792
144KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.75165510
145AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.74337529

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010352_gastrointestinal_tract_polyps3.18649082
2MP0008057_abnormal_DNA_replication3.11720722
3MP0010307_abnormal_tumor_latency2.99807933
4MP0005076_abnormal_cell_differentiation2.78998614
5MP0010094_abnormal_chromosome_stability2.66868443
6MP0000569_abnormal_digit_pigmentation2.39201921
7MP0003693_abnormal_embryo_hatching2.39181983
8MP0003111_abnormal_nucleus_morphology2.39035548
9MP0003077_abnormal_cell_cycle2.35534634
10MP0003705_abnormal_hypodermis_morpholog2.27205836
11MP0003950_abnormal_plasma_membrane2.13192219
12MP0004957_abnormal_blastocyst_morpholog2.06798400
13MP0003566_abnormal_cell_adhesion2.00749015
14MP0005409_darkened_coat_color1.94036856
15MP0005451_abnormal_body_composition1.87891592
16MP0008438_abnormal_cutaneous_collagen1.84661606
17MP0008058_abnormal_DNA_repair1.82205544
18MP0002009_preneoplasia1.81081258
19MP0000350_abnormal_cell_proliferation1.78456009
20MP0004233_abnormal_muscle_weight1.73582848
21MP0000537_abnormal_urethra_morphology1.71127616
22MP0008007_abnormal_cellular_replicative1.68352442
23MP0008877_abnormal_DNA_methylation1.65835410
24MP0005380_embryogenesis_phenotype1.65333692
25MP0001672_abnormal_embryogenesis/_devel1.65333692
26MP0003941_abnormal_skin_development1.64905575
27MP0004197_abnormal_fetal_growth/weight/1.64724249
28MP0002086_abnormal_extraembryonic_tissu1.64050005
29MP0003890_abnormal_embryonic-extraembry1.62482070
30MP0001730_embryonic_growth_arrest1.61233765
31MP0002877_abnormal_melanocyte_morpholog1.57267011
32MP0003984_embryonic_growth_retardation1.57234646
33MP0002088_abnormal_embryonic_growth/wei1.56951590
34MP0010234_abnormal_vibrissa_follicle1.54849128
35MP0002084_abnormal_developmental_patter1.54596649
36MP0003763_abnormal_thymus_physiology1.52837065
37MP0000516_abnormal_urinary_system1.49690738
38MP0005367_renal/urinary_system_phenotyp1.49690738
39MP0003121_genomic_imprinting1.46717571
40MP0003091_abnormal_cell_migration1.43853620
41MP0002396_abnormal_hematopoietic_system1.42429324
42MP0003221_abnormal_cardiomyocyte_apopto1.38719679
43MP0005623_abnormal_meninges_morphology1.37472348
44MP0001293_anophthalmia1.37301472
45MP0002085_abnormal_embryonic_tissue1.35936909
46MP0003937_abnormal_limbs/digits/tail_de1.35127089
47MP0004808_abnormal_hematopoietic_stem1.34817067
48MP0009703_decreased_birth_body1.33788531
49MP0000733_abnormal_muscle_development1.33151270
50MP0003300_gastrointestinal_ulcer1.33045664
51MP0005023_abnormal_wound_healing1.32600820
52MP0001697_abnormal_embryo_size1.32049918
53MP0003567_abnormal_fetal_cardiomyocyte1.31912629
54MP0002006_tumorigenesis1.30637598
55MP0010678_abnormal_skin_adnexa1.25653825
56MP0002166_altered_tumor_susceptibility1.24774069
57MP0000383_abnormal_hair_follicle1.20060005
58MP0003787_abnormal_imprinting1.18432586
59MP0009053_abnormal_anal_canal1.17847175
60MP0000432_abnormal_head_morphology1.17304117
61MP0001915_intracranial_hemorrhage1.15360549
62MP0003123_paternal_imprinting1.15292534
63MP0009697_abnormal_copulation1.14901555
64MP0002697_abnormal_eye_size1.13194664
65MP0000371_diluted_coat_color1.13058152
66MP0003136_yellow_coat_color1.12189777
67MP0004185_abnormal_adipocyte_glucose1.11710421
68MP0005257_abnormal_intraocular_pressure1.11311264
69MP0003453_abnormal_keratinocyte_physiol1.09837002
70MP0003828_pulmonary_edema1.09355470
71MP0010630_abnormal_cardiac_muscle1.04614000
72MP0002925_abnormal_cardiovascular_devel1.03555090
73MP0008932_abnormal_embryonic_tissue1.03532448
74MP0005275_abnormal_skin_tensile1.00282919
75MP0003448_altered_tumor_morphology0.99392192
76MP0003786_premature_aging0.99087041
77MP0002080_prenatal_lethality0.98912601
78MP0002092_abnormal_eye_morphology0.98779718
79MP0001851_eye_inflammation0.95336054
80MP0000427_abnormal_hair_cycle0.94996294
81MP0009672_abnormal_birth_weight0.93799577
82MP0005666_abnormal_adipose_tissue0.92280760
83MP0001286_abnormal_eye_development0.90170128
84MP0002060_abnormal_skin_morphology0.88620178
85MP0002796_impaired_skin_barrier0.88291395
86MP0000627_abnormal_mammary_gland0.87934611
87MP0004947_skin_inflammation0.86763248
88MP0003115_abnormal_respiratory_system0.86448045
89MP0003935_abnormal_craniofacial_develop0.84293974
90MP0004381_abnormal_hair_follicle0.84285901
91MP0000767_abnormal_smooth_muscle0.83717355
92MP0003045_fibrosis0.83458926
93MP0005408_hypopigmentation0.82852093
94MP0008961_abnormal_basal_metabolism0.82452070
95MP0000428_abnormal_craniofacial_morphol0.82254739
96MP0005503_abnormal_tendon_morphology0.82224692
97MP0003755_abnormal_palate_morphology0.82215492
98MP0005621_abnormal_cell_physiology0.81134846
99MP0005384_cellular_phenotype0.80961225
100MP0002398_abnormal_bone_marrow0.80405940
101MP0002075_abnormal_coat/hair_pigmentati0.79966570
102MP0000377_abnormal_hair_follicle0.79256863
103MP0009278_abnormal_bone_marrow0.75991231
104MP0003656_abnormal_erythrocyte_physiolo0.75979962
105MP0002210_abnormal_sex_determination0.75566526
106MP0000490_abnormal_crypts_of0.74652821
107MP0001186_pigmentation_phenotype0.74268121
108MP0009115_abnormal_fat_cell0.73836545
109MP0005375_adipose_tissue_phenotype0.73396937
110MP0001849_ear_inflammation0.73270568
111MP0002111_abnormal_tail_morphology0.72861990
112MP0000313_abnormal_cell_death0.72784590
113MP0004264_abnormal_extraembryonic_tissu0.72150999
114MP0001216_abnormal_epidermal_layer0.71369751
115MP0003943_abnormal_hepatobiliary_system0.70945061
116MP0002019_abnormal_tumor_incidence0.70911624
117MP0001661_extended_life_span0.70729019
118MP0000003_abnormal_adipose_tissue0.70452956
119MP0005508_abnormal_skeleton_morphology0.70230413
120MP0005397_hematopoietic_system_phenotyp0.69647667
121MP0001545_abnormal_hematopoietic_system0.69647667
122MP0001191_abnormal_skin_condition0.68901074
123MP0001348_abnormal_lacrimal_gland0.68727703
124MP0001784_abnormal_fluid_regulation0.68418021
125MP0001835_abnormal_antigen_presentation0.68243440
126MP0000703_abnormal_thymus_morphology0.68093479
127MP0000858_altered_metastatic_potential0.67436105
128MP0002277_abnormal_respiratory_mucosa0.67338695
129MP0004084_abnormal_cardiac_muscle0.66941194
130MP0002722_abnormal_immune_system0.66232418
131MP0002098_abnormal_vibrissa_morphology0.63619758
132MP0002998_abnormal_bone_remodeling0.61153735

Predicted human phenotypes

RankGene SetZ-score
1Chromsome breakage (HP:0040012)3.40722648
2Dysmetric saccades (HP:0000641)3.17688801
3Ankyloglossia (HP:0010296)3.04870731
4Abnormality of the fingertips (HP:0001211)2.99828291
5Chromosomal breakage induced by crosslinking agents (HP:0003221)2.97731238
6Volvulus (HP:0002580)2.94515815
7Abnormality of the labia minora (HP:0012880)2.90750594
8Abnormality of the nasal septum (HP:0000419)2.76432767
9Absent frontal sinuses (HP:0002688)2.74420819
10Abnormality of chromosome stability (HP:0003220)2.64909061
11Neoplasm of the oral cavity (HP:0100649)2.64774076
12Neonatal hypoglycemia (HP:0001998)2.63841701
13Ectopic kidney (HP:0000086)2.61700999
14Deep philtrum (HP:0002002)2.58800099
15Papillary thyroid carcinoma (HP:0002895)2.55340080
16Lip pit (HP:0100267)2.54591498
17Urethral obstruction (HP:0000796)2.51957970
18Hypoplastic ischia (HP:0003175)2.50274795
19Vertebral arch anomaly (HP:0008438)2.48226018
20Abnormality of oral frenula (HP:0000190)2.47280037
21Asymmetry of the thorax (HP:0001555)2.40502034
22Biliary tract neoplasm (HP:0100574)2.40373673
23Neoplasm of the adrenal cortex (HP:0100641)2.39652591
24Abnormality of the distal phalanx of the thumb (HP:0009617)2.38552977
25Birth length less than 3rd percentile (HP:0003561)2.35906546
26Acute myeloid leukemia (HP:0004808)2.35901466
27Long eyelashes (HP:0000527)2.35291030
28Flat acetabular roof (HP:0003180)2.32367932
29Abnormality of the ischium (HP:0003174)2.30222472
30Hematochezia (HP:0002573)2.30160802
31Deviation of the thumb (HP:0009603)2.22056725
32Curly hair (HP:0002212)2.21725392
33Impulsivity (HP:0100710)2.21055232
34Viral hepatitis (HP:0006562)2.18041109
35Rhabdomyosarcoma (HP:0002859)2.17125418
36Prostate neoplasm (HP:0100787)2.16805164
37Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.09916849
38Osteolytic defects of the hand bones (HP:0009699)2.09915126
39Osteolytic defects of the phalanges of the hand (HP:0009771)2.09915126
40Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)2.09642738
41Sandal gap (HP:0001852)2.09605987
42Transitional cell carcinoma of the bladder (HP:0006740)2.08688274
43Syringomyelia (HP:0003396)2.07949221
44Spinal cord lesions (HP:0100561)2.07949221
45Cubitus valgus (HP:0002967)2.06992626
46Uterine leiomyosarcoma (HP:0002891)2.06946191
47Leiomyosarcoma (HP:0100243)2.06946191
48Sparse lateral eyebrow (HP:0005338)2.03825499
49Short humerus (HP:0005792)2.02710882
50Prominent nose (HP:0000448)2.02009857
51Intestinal fistula (HP:0100819)2.01000952
52Overgrowth (HP:0001548)1.99935838
53Hypoplastic labia majora (HP:0000059)1.99815180
54Medulloblastoma (HP:0002885)1.99500518
55Anal stenosis (HP:0002025)1.97388518
56Astrocytoma (HP:0009592)1.97320288
57Abnormality of the astrocytes (HP:0100707)1.97320288
58Insidious onset (HP:0003587)1.97228138
59Termporal pattern (HP:0011008)1.97228138
60Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.97121253
61Short 4th metacarpal (HP:0010044)1.97121253
62Bladder neoplasm (HP:0009725)1.96151491
63Bladder carcinoma (HP:0002862)1.96151491
64Ependymoma (HP:0002888)1.95891374
65Proximal placement of thumb (HP:0009623)1.92889664
66Malignant gastrointestinal tract tumors (HP:0006749)1.92051211
67Gastrointestinal carcinoma (HP:0002672)1.92051211
68Heterotopia (HP:0002282)1.90724610
69Long clavicles (HP:0000890)1.89453963
70Abnormality of the radial head (HP:0003995)1.89002086
71Overlapping toe (HP:0001845)1.88496348
72Broad face (HP:0000283)1.88342158
73Supernumerary ribs (HP:0005815)1.88223053
74Embryonal renal neoplasm (HP:0011794)1.88204895
75Aplasia/Hypoplasia of the uvula (HP:0010293)1.87393502
76Skull defect (HP:0001362)1.86040847
77Abnormal foot bone ossification (HP:0010675)1.85484212
78Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.85404333
79Hyperacusis (HP:0010780)1.85136832
80Limited elbow extension (HP:0001377)1.83729398
81Short chin (HP:0000331)1.83288445
82Progressive external ophthalmoplegia (HP:0000590)1.83147066
83Narrow palate (HP:0000189)1.83074113
84Abnormality of the labia majora (HP:0012881)1.83050236
85Aplasia/hypoplasia of the humerus (HP:0006507)1.82771994
86Abnormality of chromosome segregation (HP:0002916)1.80217618
87Subaortic stenosis (HP:0001682)1.79905430
88Abnormality of the left ventricular outflow tract (HP:0011103)1.79905430
89Glioma (HP:0009733)1.79280929
90Acute lymphatic leukemia (HP:0006721)1.79226728
91Absent radius (HP:0003974)1.76174924
92Germ cell neoplasia (HP:0100728)1.75749695
93Colon cancer (HP:0003003)1.75215577
94Truncal obesity (HP:0001956)1.75013771
95Macroorchidism (HP:0000053)1.73756485
96Meckel diverticulum (HP:0002245)1.73155661
97Low anterior hairline (HP:0000294)1.73059364
98Obsessive-compulsive behavior (HP:0000722)1.72907591
99Shallow orbits (HP:0000586)1.72698437
100Colitis (HP:0002583)1.71562082
101Hypoplasia of the maxilla (HP:0000327)1.71482694
102Cerebral aneurysm (HP:0004944)1.70688148
103Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.70132928
104Abnormality of the frontal sinuses (HP:0002687)1.70047445
105T lymphocytopenia (HP:0005403)1.69286354
106Agnosia (HP:0010524)1.69038807
107Subacute progressive viral hepatitis (HP:0006572)1.68954822
108Cystic hygroma (HP:0000476)1.68358405
109Persistence of primary teeth (HP:0006335)1.67495931
110Depressed nasal tip (HP:0000437)1.66253358
111Facial hemangioma (HP:0000329)1.66009436
112Broad thumb (HP:0011304)1.65894750
113Abnormality of the epiphyses of the hand (HP:0005924)1.65713458
114Increased nuchal translucency (HP:0010880)1.64426119
115Cutaneous melanoma (HP:0012056)1.64022637
116Supernumerary bones of the axial skeleton (HP:0009144)1.63139604
117Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.62580347
118Dislocated radial head (HP:0003083)1.62450084
119Thyroid carcinoma (HP:0002890)1.61763734
120Hypopigmentation of the fundus (HP:0007894)1.60734820
121Cafe-au-lait spot (HP:0000957)1.59538341
122Esophageal atresia (HP:0002032)1.59039017
123Relative macrocephaly (HP:0004482)1.58839615
124Renal cell carcinoma (HP:0005584)1.58389650
125Absent forearm bone (HP:0003953)1.57391161
126Aplasia involving forearm bones (HP:0009822)1.57391161
127Ankle contracture (HP:0006466)1.57206613
128High pitched voice (HP:0001620)1.56971708
129Periodontitis (HP:0000704)1.56216297
130Abnormality of the ileum (HP:0001549)1.56193650
131Abnormal biliary tract morphology (HP:0012440)1.56060411
132Selective tooth agenesis (HP:0001592)1.55929060
133Micronodular cirrhosis (HP:0001413)1.55924552
134Coarse hair (HP:0002208)1.55162252
135Ulnar bowing (HP:0003031)1.55013102
13611 pairs of ribs (HP:0000878)1.54462980
137Abnormality of the hepatic vasculature (HP:0006707)1.53915009
138Abnormality of the preputium (HP:0100587)1.53823280
139Rectal prolapse (HP:0002035)1.53694583
140Genu recurvatum (HP:0002816)1.53567325
141Myelodysplasia (HP:0002863)1.53224231
142Thick eyebrow (HP:0000574)1.52595880
143Right ventricular cardiomyopathy (HP:0011663)1.52549367
144Missing ribs (HP:0000921)1.52064056
145Supernumerary spleens (HP:0009799)1.51747798
146Nephroblastoma (Wilms tumor) (HP:0002667)1.51736793
147Breast hypoplasia (HP:0003187)1.51664755
148Spinal muscular atrophy (HP:0007269)1.51458808
149Septate vagina (HP:0001153)1.51273918
150Abnormality involving the epiphyses of the upper limbs (HP:0003839)1.50741763
151Mitral valve prolapse (HP:0001634)1.50586065
152Large earlobe (HP:0009748)1.50434633
153Wrist flexion contracture (HP:0001239)1.50408317
154Arnold-Chiari malformation (HP:0002308)1.49261873
155Arterial tortuosity (HP:0005116)1.48023100
156Bicuspid aortic valve (HP:0001647)1.47878074
157Dental malocclusion (HP:0000689)1.47618319
158Abnormality of the salivary glands (HP:0010286)1.47015568
159IgA deficiency (HP:0002720)1.46924217
160Broad nasal tip (HP:0000455)1.46698603

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK125.16004814
2LATS13.32329717
3ZAK3.20186796
4FRK2.71395703
5CDC72.57734987
6EPHA22.50069388
7PRPF4B2.27202493
8STK32.14467165
9BRD42.08939812
10TRIB32.04227676
11SRPK12.01422045
12CAMK1D1.91796375
13STK101.74797112
14ICK1.74103225
15MAP3K21.67011038
16TLK11.65601211
17SMG11.65580047
18BRSK21.54985077
19MKNK21.54229127
20MELK1.53478324
21NEK21.50071381
22WEE11.49566568
23STK41.47074328
24TTK1.46946671
25CDK61.45209883
26CDK91.40516245
27PIM11.39522602
28PLK31.38338009
29CHEK21.38108488
30NUAK11.37707570
31FGFR21.37073187
32MAP3K141.36819430
33STK38L1.33502361
34FGFR31.32487819
35MARK31.28634782
36ATM1.27294292
37KSR21.26334139
38MAP3K131.25788376
39TTN1.24959984
40FGFR41.23742505
41ATR1.22038282
42AKT31.21901325
43CHEK11.18605138
44CHUK1.18177061
45MKNK11.18074202
46ERBB41.15446958
47MTOR1.13164716
48AURKB1.12748074
49RPS6KA51.12283058
50TRPM71.11288692
51RPS6KB21.11120900
52NEK91.10560355
53CDK41.02368104
54CDK71.01495715
55PLK11.00551534
56CAMK1G1.00375760
57ALK0.96728575
58MST1R0.96071368
59TAF10.95692116
60DMPK0.94663710
61RPS6KA40.90656090
62MAP3K100.88483554
63MAP2K30.88222263
64MET0.87327984
65ACVR1B0.87103130
66PDGFRB0.85604711
67RAF10.80393023
68CSNK1D0.79833073
69JAK30.78055398
70* CDK20.77917749
71MAP3K80.76823145
72TSSK60.76811191
73SCYL20.74533366
74NEK60.70714291
75SGK30.69878661
76RET0.69629982
77PLK40.67723875
78EIF2AK20.67240035
79RIPK10.66400086
80CDK10.66191412
81KSR10.65766369
82PKN20.65480492
83MARK20.65195412
84BMPR20.65165726
85SGK20.64956904
86LATS20.63647135
87RIPK40.63318656
88WNK10.62118918
89FLT30.61917956
90EIF2AK30.61874401
91BLK0.61640720
92BMX0.60278682
93MAPK140.59528543
94STK240.59202064
95JAK10.58670303
96EEF2K0.58330338
97SIK10.55347278
98MAP3K60.55317745
99EPHA30.53219304
100VRK10.53074556
101MST40.52832251
102PRKDC0.52107713
103MAP3K70.51365827
104PIK3CA0.50572828
105AKT10.50120065
106YES10.49356916
107FGFR10.49321902
108MAPK10.48654417
109NLK0.47878903
110PAK20.47769930
111MAPK110.46876697
112STK380.46269980
113MAPK100.46247795
114TGFBR20.46066021
115STK390.45941022
116JAK20.45921285
117TEC0.45832956
118RPS6KB10.45543203
119PBK0.45088163
120CSK0.44625131
121PDGFRA0.44048639
122DDR20.43801723
123PRKAA20.43800205
124PTK60.42753219
125MAP3K90.42563972
126PNCK0.42279338
127PASK0.42202365
128IKBKB0.41849096
129IRAK10.41823939
130GSK3A0.41664752
131BTK0.41399779
132INSR0.40983187
133IRAK40.40062557
134RPS6KC10.39070433
135RPS6KL10.39070433

Predicted pathways (KEGG)

RankGene SetZ-score
1Systemic lupus erythematosus_Homo sapiens_hsa053222.92538419
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.52798859
3Cell cycle_Homo sapiens_hsa041102.12346590
4RNA transport_Homo sapiens_hsa030132.05033892
5MicroRNAs in cancer_Homo sapiens_hsa052062.03143571
6Fanconi anemia pathway_Homo sapiens_hsa034602.02048319
7One carbon pool by folate_Homo sapiens_hsa006701.86974744
8Non-homologous end-joining_Homo sapiens_hsa034501.85335367
9mRNA surveillance pathway_Homo sapiens_hsa030151.81384065
10Mismatch repair_Homo sapiens_hsa034301.78897296
11Adherens junction_Homo sapiens_hsa045201.77880534
12Viral carcinogenesis_Homo sapiens_hsa052031.76190680
13Lysine degradation_Homo sapiens_hsa003101.72280481
14p53 signaling pathway_Homo sapiens_hsa041151.66466947
15NF-kappa B signaling pathway_Homo sapiens_hsa040641.57960159
16Small cell lung cancer_Homo sapiens_hsa052221.55928982
17Transcriptional misregulation in cancer_Homo sapiens_hsa052021.50537199
18TGF-beta signaling pathway_Homo sapiens_hsa043501.50532496
19Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.48373521
20Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.47705221
21Homologous recombination_Homo sapiens_hsa034401.46701255
22Basal transcription factors_Homo sapiens_hsa030221.42457659
23ErbB signaling pathway_Homo sapiens_hsa040121.39406972
24Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.35830411
25Glioma_Homo sapiens_hsa052141.34338878
26RNA degradation_Homo sapiens_hsa030181.34048843
27Spliceosome_Homo sapiens_hsa030401.33436422
28Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.32013570
29Bladder cancer_Homo sapiens_hsa052191.31768469
30Prostate cancer_Homo sapiens_hsa052151.29998790
31Herpes simplex infection_Homo sapiens_hsa051681.26078451
32Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.21383145
33DNA replication_Homo sapiens_hsa030301.21199155
34Nucleotide excision repair_Homo sapiens_hsa034201.20923596
35Central carbon metabolism in cancer_Homo sapiens_hsa052301.20731184
36Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.16931903
37Antigen processing and presentation_Homo sapiens_hsa046121.15006427
38Neurotrophin signaling pathway_Homo sapiens_hsa047221.14747416
39Chronic myeloid leukemia_Homo sapiens_hsa052201.14490365
40Dorso-ventral axis formation_Homo sapiens_hsa043201.12216625
41Choline metabolism in cancer_Homo sapiens_hsa052311.10142185
42HTLV-I infection_Homo sapiens_hsa051661.09950589
43NOD-like receptor signaling pathway_Homo sapiens_hsa046211.09428763
44Proteoglycans in cancer_Homo sapiens_hsa052051.08528585
45Alcoholism_Homo sapiens_hsa050341.08333670
46ECM-receptor interaction_Homo sapiens_hsa045121.07162596
47Longevity regulating pathway - mammal_Homo sapiens_hsa042111.06434064
48mTOR signaling pathway_Homo sapiens_hsa041501.06120394
49FoxO signaling pathway_Homo sapiens_hsa040681.04610112
50VEGF signaling pathway_Homo sapiens_hsa043701.02195455
51Hippo signaling pathway_Homo sapiens_hsa043901.02122457
52Focal adhesion_Homo sapiens_hsa045101.00197597
53Measles_Homo sapiens_hsa051620.99141129
54Estrogen signaling pathway_Homo sapiens_hsa049150.97868602
55Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.94553098
56Hepatitis B_Homo sapiens_hsa051610.93018374
57Pancreatic cancer_Homo sapiens_hsa052120.92473848
58Insulin signaling pathway_Homo sapiens_hsa049100.92048875
59TNF signaling pathway_Homo sapiens_hsa046680.91551272
60Toxoplasmosis_Homo sapiens_hsa051450.91472696
61Epstein-Barr virus infection_Homo sapiens_hsa051690.89760967
62Hematopoietic cell lineage_Homo sapiens_hsa046400.88338195
63Leishmaniasis_Homo sapiens_hsa051400.88143854
64Osteoclast differentiation_Homo sapiens_hsa043800.87760175
65Leukocyte transendothelial migration_Homo sapiens_hsa046700.87475771
66Pathways in cancer_Homo sapiens_hsa052000.86001864
67Jak-STAT signaling pathway_Homo sapiens_hsa046300.85941064
68Melanoma_Homo sapiens_hsa052180.85359445
69Intestinal immune network for IgA production_Homo sapiens_hsa046720.84917877
70Asthma_Homo sapiens_hsa053100.84767784
71Colorectal cancer_Homo sapiens_hsa052100.84145944
72Regulation of actin cytoskeleton_Homo sapiens_hsa048100.83525399
73Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.81824710
74Viral myocarditis_Homo sapiens_hsa054160.81375362
75Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.80992240
76AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.79584075
77GnRH signaling pathway_Homo sapiens_hsa049120.78507900
78Phospholipase D signaling pathway_Homo sapiens_hsa040720.77916642
79Apoptosis_Homo sapiens_hsa042100.77313826
80Renal cell carcinoma_Homo sapiens_hsa052110.76649200
81Long-term potentiation_Homo sapiens_hsa047200.76122417
82Basal cell carcinoma_Homo sapiens_hsa052170.76108647
83Sphingolipid signaling pathway_Homo sapiens_hsa040710.75867924
84Allograft rejection_Homo sapiens_hsa053300.75426228
85Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.75398021
86Influenza A_Homo sapiens_hsa051640.75332975
87PI3K-Akt signaling pathway_Homo sapiens_hsa041510.72487649
88T cell receptor signaling pathway_Homo sapiens_hsa046600.71577118
89RNA polymerase_Homo sapiens_hsa030200.70870693
90Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.70775155
91Malaria_Homo sapiens_hsa051440.69685076
92Endometrial cancer_Homo sapiens_hsa052130.69573073
93Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.69184385
94Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.68344430
95B cell receptor signaling pathway_Homo sapiens_hsa046620.66841581
96Inositol phosphate metabolism_Homo sapiens_hsa005620.66039475
97Notch signaling pathway_Homo sapiens_hsa043300.65930617
98Fatty acid biosynthesis_Homo sapiens_hsa000610.65450467
99Amoebiasis_Homo sapiens_hsa051460.65383388
100Renin-angiotensin system_Homo sapiens_hsa046140.65381701
101Thyroid hormone signaling pathway_Homo sapiens_hsa049190.64865637
102AMPK signaling pathway_Homo sapiens_hsa041520.64696972
103Tight junction_Homo sapiens_hsa045300.63108178
104MAPK signaling pathway_Homo sapiens_hsa040100.62441115
105Autoimmune thyroid disease_Homo sapiens_hsa053200.62320028
106Acute myeloid leukemia_Homo sapiens_hsa052210.61339877
107Insulin resistance_Homo sapiens_hsa049310.60933048
108Adipocytokine signaling pathway_Homo sapiens_hsa049200.59536440
109Phosphatidylinositol signaling system_Homo sapiens_hsa040700.59047777
110Selenocompound metabolism_Homo sapiens_hsa004500.58054641
111Tuberculosis_Homo sapiens_hsa051520.55592074
112Type II diabetes mellitus_Homo sapiens_hsa049300.55521657
113Platelet activation_Homo sapiens_hsa046110.54821157
114Legionellosis_Homo sapiens_hsa051340.54385336
115Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.54279311
116HIF-1 signaling pathway_Homo sapiens_hsa040660.54028150
117Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.53880070
118Chemokine signaling pathway_Homo sapiens_hsa040620.53131918
119Thyroid cancer_Homo sapiens_hsa052160.52659069
120Prolactin signaling pathway_Homo sapiens_hsa049170.52150179
121Toll-like receptor signaling pathway_Homo sapiens_hsa046200.51916978
122Wnt signaling pathway_Homo sapiens_hsa043100.51821238
123Non-small cell lung cancer_Homo sapiens_hsa052230.51479807
124Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.49208809
125Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.48222427
126Base excision repair_Homo sapiens_hsa034100.47765998
127RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.47473864
128Hepatitis C_Homo sapiens_hsa051600.46908880

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