NUP107

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)5.02651024
2protein localization to kinetochore (GO:0034501)4.99880130
3DNA strand elongation involved in DNA replication (GO:0006271)4.92969607
4* nuclear pore organization (GO:0006999)4.76996660
5* nuclear pore complex assembly (GO:0051292)4.73429870
6DNA replication initiation (GO:0006270)4.71973002
7DNA strand elongation (GO:0022616)4.68179246
8nucleobase biosynthetic process (GO:0046112)4.50740474
9telomere maintenance via semi-conservative replication (GO:0032201)4.45149675
10DNA replication checkpoint (GO:0000076)4.42486565
11* mitotic nuclear envelope disassembly (GO:0007077)4.40493394
12IMP biosynthetic process (GO:0006188)4.32788899
13mitotic metaphase plate congression (GO:0007080)4.27092513
14establishment of integrated proviral latency (GO:0075713)4.20728497
15purine nucleobase biosynthetic process (GO:0009113)4.17759697
16protein localization to chromosome, centromeric region (GO:0071459)4.15539193
17mitotic chromosome condensation (GO:0007076)4.15474398
18telomere maintenance via recombination (GO:0000722)4.14009108
19DNA replication-dependent nucleosome organization (GO:0034723)4.13921721
20DNA replication-dependent nucleosome assembly (GO:0006335)4.13921721
21mitotic sister chromatid segregation (GO:0000070)4.13367061
22mitotic recombination (GO:0006312)4.10426002
23* nuclear envelope disassembly (GO:0051081)4.08820147
24* membrane disassembly (GO:0030397)4.08820147
25formation of translation preinitiation complex (GO:0001731)4.07698895
26kinetochore organization (GO:0051383)3.99892598
27sister chromatid segregation (GO:0000819)3.99438407
28chromatin remodeling at centromere (GO:0031055)3.98282164
29DNA ligation (GO:0006266)3.96896510
30folic acid-containing compound biosynthetic process (GO:0009396)3.91138962
31CENP-A containing nucleosome assembly (GO:0034080)3.90103201
32non-recombinational repair (GO:0000726)3.85303085
33double-strand break repair via nonhomologous end joining (GO:0006303)3.85303085
34IMP metabolic process (GO:0046040)3.77528945
35metaphase plate congression (GO:0051310)3.75989111
36regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.73960481
37negative regulation of DNA-dependent DNA replication (GO:2000104)3.72936549
38DNA duplex unwinding (GO:0032508)3.72805054
39DNA geometric change (GO:0032392)3.72208602
40DNA replication-independent nucleosome assembly (GO:0006336)3.71176116
41DNA replication-independent nucleosome organization (GO:0034724)3.71176116
42DNA catabolic process, exonucleolytic (GO:0000738)3.67997620
43telomere maintenance via telomere lengthening (GO:0010833)3.67815271
44attachment of spindle microtubules to kinetochore (GO:0008608)3.65070958
45regulation of spindle organization (GO:0090224)3.64985623
46replication fork processing (GO:0031297)3.64477749
47regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.59643242
48positive regulation of chromosome segregation (GO:0051984)3.53408142
49nucleotide-excision repair, DNA gap filling (GO:0006297)3.48797196
50* pore complex assembly (GO:0046931)3.47421754
51regulation of DNA endoreduplication (GO:0032875)3.46233715
52establishment of chromosome localization (GO:0051303)3.45593451
53somatic hypermutation of immunoglobulin genes (GO:0016446)3.45287484
54somatic diversification of immune receptors via somatic mutation (GO:0002566)3.45287484
55kinetochore assembly (GO:0051382)3.44401446
56proteasome assembly (GO:0043248)3.43719302
57maturation of SSU-rRNA (GO:0030490)3.39128520
58synapsis (GO:0007129)3.38182410
59histone exchange (GO:0043486)3.35623575
60dosage compensation (GO:0007549)3.35595947
61ribosome biogenesis (GO:0042254)3.33667375
62ribosome assembly (GO:0042255)3.30898048
63DNA topological change (GO:0006265)3.30801987
64regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.30190624
65regulation of mitotic spindle checkpoint (GO:1903504)3.30190624
66regulation of chromosome segregation (GO:0051983)3.28036666
67mitotic sister chromatid cohesion (GO:0007064)3.26193163
68chromatin assembly or disassembly (GO:0006333)3.24948952
69meiotic chromosome segregation (GO:0045132)3.24896841
70regulation of mitotic spindle organization (GO:0060236)3.24515961
71spindle checkpoint (GO:0031577)3.23550591
72maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.23069305
73negative regulation of chromosome segregation (GO:0051985)3.21378717
74positive regulation of mitotic sister chromatid separation (GO:1901970)3.21364720
75positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.21364720
76positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.21364720
77regulation of centrosome cycle (GO:0046605)3.20849920
78DNA conformation change (GO:0071103)3.20597923
79regulation of sister chromatid cohesion (GO:0007063)3.19423614
80mitotic G2/M transition checkpoint (GO:0044818)3.19166734
81regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.18302708
82* nuclear envelope organization (GO:0006998)3.17542240
83protein localization to chromosome (GO:0034502)3.16472104
84anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.15779798
85negative regulation of mitotic sister chromatid separation (GO:2000816)3.15661312
86negative regulation of mitotic sister chromatid segregation (GO:0033048)3.15661312
87negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.15661312
88negative regulation of sister chromatid segregation (GO:0033046)3.15661312
89regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.15490486
90spindle assembly checkpoint (GO:0071173)3.15216810
91negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.14094794
92regulation of mitotic metaphase/anaphase transition (GO:0030071)3.12601020
93chromosome segregation (GO:0007059)3.10645989
94establishment of viral latency (GO:0019043)3.10616192
95mitotic spindle assembly checkpoint (GO:0007094)3.10412680
96maturation of 5.8S rRNA (GO:0000460)3.10270031
97regulation of histone H3-K9 methylation (GO:0051570)3.10153232
98heterochromatin organization (GO:0070828)3.09934390
99telomere maintenance (GO:0000723)3.09738497
100negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.09288996
101viral mRNA export from host cell nucleus (GO:0046784)3.09192272
102telomere organization (GO:0032200)3.08683402
103regulation of centrosome duplication (GO:0010824)3.08400949
104mitotic spindle checkpoint (GO:0071174)3.08061012
105regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.07746510
106resolution of meiotic recombination intermediates (GO:0000712)3.03460261
107ribosomal small subunit assembly (GO:0000028)3.03451308
108postreplication repair (GO:0006301)3.03291850
109ATP-dependent chromatin remodeling (GO:0043044)3.01553085
110DNA strand renaturation (GO:0000733)3.00747506
111protein K6-linked ubiquitination (GO:0085020)3.00442650
112regulation of mitotic sister chromatid separation (GO:0010965)3.00220310
113regulation of mitotic sister chromatid segregation (GO:0033047)3.00220310
114regulation of sister chromatid segregation (GO:0033045)3.00220310
115translesion synthesis (GO:0019985)2.99393461
116regulation of double-strand break repair via homologous recombination (GO:0010569)2.99372281
117negative regulation of DNA recombination (GO:0045910)2.97666928
118ribonucleoprotein complex biogenesis (GO:0022613)2.96432462
119regulation of helicase activity (GO:0051095)2.96349533
120regulation of nuclear cell cycle DNA replication (GO:0033262)2.94195060
121chromosome condensation (GO:0030261)2.89938362
122spliceosomal snRNP assembly (GO:0000387)2.89655919
123regulation of centriole replication (GO:0046599)2.89492313
124rRNA processing (GO:0006364)2.89287837
125DNA double-strand break processing (GO:0000729)2.88221600

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXM1_23109430_ChIP-Seq_U2OS_Human4.96389645
2* E2F4_17652178_ChIP-ChIP_JURKAT_Human4.15933971
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.05928189
4FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.44973560
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.38463213
6MYC_19079543_ChIP-ChIP_MESCs_Mouse2.95130206
7* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.73380623
8KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.57554487
9* EST1_17652178_ChIP-ChIP_JURKAT_Human2.54635635
10* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.53125817
11EGR1_19374776_ChIP-ChIP_THP-1_Human2.39656732
12* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.38158480
13AR_21909140_ChIP-Seq_LNCAP_Human2.36009348
14E2F1_21310950_ChIP-Seq_MCF-7_Human2.27029491
15* ETS1_20019798_ChIP-Seq_JURKAT_Human2.26108545
16* GABP_17652178_ChIP-ChIP_JURKAT_Human2.23583823
17* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.23419112
18* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.23171414
19MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.20637532
20CREB1_15753290_ChIP-ChIP_HEK293T_Human2.20393298
21* XRN2_22483619_ChIP-Seq_HELA_Human2.18527119
22HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.07363898
23CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.05387569
24* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.05374345
25E2F7_22180533_ChIP-Seq_HELA_Human10.1938179
26MYCN_18555785_ChIP-Seq_MESCs_Mouse1.92899907
27* VDR_23849224_ChIP-Seq_CD4+_Human1.91018485
28E2F1_18555785_ChIP-Seq_MESCs_Mouse1.81034668
29MYC_22102868_ChIP-Seq_BL_Human1.79619600
30* FOXP3_21729870_ChIP-Seq_TREG_Human1.77662925
31POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.74532298
32DCP1A_22483619_ChIP-Seq_HELA_Human1.74119179
33NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.73554313
34NANOG_18555785_ChIP-Seq_MESCs_Mouse1.70582527
35PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.67558734
36TTF2_22483619_ChIP-Seq_HELA_Human1.66627033
37ELK1_19687146_ChIP-ChIP_HELA_Human1.64799525
38* GABP_19822575_ChIP-Seq_HepG2_Human1.64353681
39YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.64281551
40THAP11_20581084_ChIP-Seq_MESCs_Mouse1.62986496
41EWS_26573619_Chip-Seq_HEK293_Human1.59978896
42ELF1_17652178_ChIP-ChIP_JURKAT_Human1.52932036
43ZFX_18555785_ChIP-Seq_MESCs_Mouse1.50561636
44CIITA_25753668_ChIP-Seq_RAJI_Human1.50026871
45MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.48983479
46KDM5A_27292631_Chip-Seq_BREAST_Human1.48433440
47RBPJ_22232070_ChIP-Seq_NCS_Mouse1.47307507
48SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.45402068
49* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.45301104
50POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.41615661
51FUS_26573619_Chip-Seq_HEK293_Human1.39908076
52HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.39364865
53FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.38045759
54TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.35621102
55* ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.34137102
56SOX2_18555785_ChIP-Seq_MESCs_Mouse1.33414754
57ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.33333219
58CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.32892721
59SALL1_21062744_ChIP-ChIP_HESCs_Human1.31918808
60ZNF274_21170338_ChIP-Seq_K562_Hela1.30698950
61STAT3_1855785_ChIP-Seq_MESCs_Mouse1.30493267
62HOXB4_20404135_ChIP-ChIP_EML_Mouse1.28097203
63VDR_22108803_ChIP-Seq_LS180_Human1.24326706
64NANOG_16153702_ChIP-ChIP_HESCs_Human1.22954749
65* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.22518901
66POU5F1_16153702_ChIP-ChIP_HESCs_Human1.22261706
67POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.21341331
68YY1_21170310_ChIP-Seq_MESCs_Mouse1.20149467
69TFEB_21752829_ChIP-Seq_HELA_Human1.19551775
70NOTCH1_21737748_ChIP-Seq_TLL_Human1.18157889
71* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.16843845
72SOX2_16153702_ChIP-ChIP_HESCs_Human1.16520752
73E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.14907390
74TP63_19390658_ChIP-ChIP_HaCaT_Human1.14758975
75PADI4_21655091_ChIP-ChIP_MCF-7_Human1.13896676
76PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.13445776
77SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.13436532
78ESR1_15608294_ChIP-ChIP_MCF-7_Human1.13308914
79HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.11485540
80DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.10609889
81CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.08559418
82FLI1_27457419_Chip-Seq_LIVER_Mouse1.06579754
83PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.05405478
84POU3F2_20337985_ChIP-ChIP_501MEL_Human1.05291812
85ERG_20887958_ChIP-Seq_HPC-7_Mouse1.05192320
86* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.04021402
87CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.03291421
88NANOG_21062744_ChIP-ChIP_HESCs_Human1.02823725
89KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.01795442
90KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.99431731
91SRF_21415370_ChIP-Seq_HL-1_Mouse0.98674225
92VDR_21846776_ChIP-Seq_THP-1_Human0.96358690
93CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.96252543
94TCF3_18692474_ChIP-Seq_MEFs_Mouse0.94606260
95ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.91026852
96NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.90404173
97CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.89889579
98SOX17_20123909_ChIP-Seq_XEN_Mouse0.89877895
99SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.88473887
100* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.87621097
101NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.86037337
102FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.85828569
103SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.85550512
104* HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.85281107
105IRF1_19129219_ChIP-ChIP_H3396_Human0.84680580
106NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.83266046
107MYC_18940864_ChIP-ChIP_HL60_Human0.82858920
108KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.82566270
109KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.82566270
110KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.82566270
111GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.82274897
112SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.81938104
113TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.81428339
114IGF1R_20145208_ChIP-Seq_DFB_Human0.81238032
115* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.78991774
116CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.78206107
117FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.77016157
118PCGF2_27294783_Chip-Seq_ESCs_Mouse0.71627743
119TAF15_26573619_Chip-Seq_HEK293_Human0.71254668
120P300_19829295_ChIP-Seq_ESCs_Human0.69343006
121CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.67638520
122RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.67412587
123ELK1_22589737_ChIP-Seq_MCF10A_Human0.63499116
124MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.63260936
125NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.60561913
126EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.59565163
127GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.56857879
128GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.56739519

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.90076845
2MP0010094_abnormal_chromosome_stability4.89248930
3MP0003111_abnormal_nucleus_morphology4.65892803
4MP0004957_abnormal_blastocyst_morpholog4.24924091
5MP0008057_abnormal_DNA_replication4.24905433
6MP0003077_abnormal_cell_cycle4.11374022
7MP0008058_abnormal_DNA_repair3.13527434
8MP0009697_abnormal_copulation2.78813459
9MP0010352_gastrointestinal_tract_polyps2.71456385
10MP0008007_abnormal_cellular_replicative2.69287601
11MP0008932_abnormal_embryonic_tissue2.66116216
12MP0001730_embryonic_growth_arrest2.63054383
13MP0003123_paternal_imprinting2.59645121
14MP0000350_abnormal_cell_proliferation2.43865074
15MP0002396_abnormal_hematopoietic_system2.37792944
16MP0008877_abnormal_DNA_methylation2.19572183
17MP0010307_abnormal_tumor_latency2.17702110
18MP0001672_abnormal_embryogenesis/_devel1.95359077
19MP0005380_embryogenesis_phenotype1.95359077
20MP0001697_abnormal_embryo_size1.91994060
21MP0000372_irregular_coat_pigmentation1.87914327
22MP0002938_white_spotting1.84553497
23MP0003984_embryonic_growth_retardation1.77848563
24MP0002085_abnormal_embryonic_tissue1.73865769
25MP0002088_abnormal_embryonic_growth/wei1.73500600
26MP0002084_abnormal_developmental_patter1.73494496
27MP0002080_prenatal_lethality1.71814862
28MP0003786_premature_aging1.69302764
29MP0004197_abnormal_fetal_growth/weight/1.68206433
30MP0003121_genomic_imprinting1.67699444
31MP0002102_abnormal_ear_morphology1.62198651
32MP0002086_abnormal_extraembryonic_tissu1.60654922
33MP0000490_abnormal_crypts_of1.60227264
34MP0004808_abnormal_hematopoietic_stem1.56894595
35MP0005076_abnormal_cell_differentiation1.54414178
36MP0006072_abnormal_retinal_apoptosis1.48617813
37MP0002019_abnormal_tumor_incidence1.47065278
38MP0000313_abnormal_cell_death1.44321496
39MP0003890_abnormal_embryonic-extraembry1.43268991
40MP0003136_yellow_coat_color1.40649678
41MP0010030_abnormal_orbit_morphology1.36406800
42MP0003718_maternal_effect1.35120274
43MP0003567_abnormal_fetal_cardiomyocyte1.33428269
44MP0002234_abnormal_pharynx_morphology1.31919556
45MP0000537_abnormal_urethra_morphology1.29790344
46MP0005408_hypopigmentation1.28200889
47MP0003705_abnormal_hypodermis_morpholog1.25978044
48MP0005397_hematopoietic_system_phenotyp1.22974810
49MP0001545_abnormal_hematopoietic_system1.22974810
50MP0004133_heterotaxia1.20544153
51MP0006035_abnormal_mitochondrial_morpho1.17410080
52MP0001293_anophthalmia1.16807461
53MP0000703_abnormal_thymus_morphology1.16729988
54MP0009333_abnormal_splenocyte_physiolog1.16052309
55MP0003763_abnormal_thymus_physiology1.14104813
56MP0002210_abnormal_sex_determination1.10298362
57MP0008789_abnormal_olfactory_epithelium1.08092254
58MP0002751_abnormal_autonomic_nervous1.04112325
59MP0005171_absent_coat_pigmentation1.03500515
60MP0001915_intracranial_hemorrhage1.01660666
61MP0002233_abnormal_nose_morphology1.00454944
62MP0005023_abnormal_wound_healing0.99941674
63MP0002398_abnormal_bone_marrow0.99862557
64MP0009053_abnormal_anal_canal0.97267733
65MP0001145_abnormal_male_reproductive0.96611160
66MP0002722_abnormal_immune_system0.95264069
67MP0003186_abnormal_redox_activity0.94275803
68MP0009672_abnormal_birth_weight0.92559045
69MP0006054_spinal_hemorrhage0.91711069
70MP0005075_abnormal_melanosome_morpholog0.90939089
71MP0000647_abnormal_sebaceous_gland0.90742100
72MP0000689_abnormal_spleen_morphology0.90235282
73MP0003119_abnormal_digestive_system0.89579878
74MP0003937_abnormal_limbs/digits/tail_de0.89418243
75MP0004147_increased_porphyrin_level0.89312255
76MP0008995_early_reproductive_senescence0.89176583
77MP0002111_abnormal_tail_morphology0.88700633
78MP0001529_abnormal_vocalization0.88001644
79MP0005384_cellular_phenotype0.86621560
80MP0001929_abnormal_gametogenesis0.86056159
81MP0003566_abnormal_cell_adhesion0.85882256
82MP0003315_abnormal_perineum_morphology0.84146131
83MP0005621_abnormal_cell_physiology0.84084552
84MP0009703_decreased_birth_body0.83419566
85MP0000653_abnormal_sex_gland0.83129802
86MP0002092_abnormal_eye_morphology0.82860118
87MP0003941_abnormal_skin_development0.82604958
88MP0003943_abnormal_hepatobiliary_system0.81991977
89MP0002653_abnormal_ependyma_morphology0.81385922
90MP0003787_abnormal_imprinting0.81335218
91MP0005391_vision/eye_phenotype0.81163569
92MP0004264_abnormal_extraembryonic_tissu0.79237908
93MP0006036_abnormal_mitochondrial_physio0.78949964
94MP0001849_ear_inflammation0.78344524
95MP0000358_abnormal_cell_content/0.77866967
96MP0003115_abnormal_respiratory_system0.77234349
97MP0005253_abnormal_eye_physiology0.77199805
98MP0005187_abnormal_penis_morphology0.76777002
99MP0005395_other_phenotype0.76720596
100MP0003698_abnormal_male_reproductive0.76036936
101MP0002160_abnormal_reproductive_system0.75493495
102MP0001119_abnormal_female_reproductive0.75455187
103MP0000631_abnormal_neuroendocrine_gland0.74750660
104MP0000858_altered_metastatic_potential0.74584851
105MP0000428_abnormal_craniofacial_morphol0.74383261
106MP0002429_abnormal_blood_cell0.73912152
107MP0001286_abnormal_eye_development0.73500750
108MP0003221_abnormal_cardiomyocyte_apopto0.73135939
109MP0006292_abnormal_olfactory_placode0.71065185
110MP0001324_abnormal_eye_pigmentation0.70308809
111MP0009278_abnormal_bone_marrow0.68913109
112MP0002697_abnormal_eye_size0.67733209
113MP0002075_abnormal_coat/hair_pigmentati0.66835554
114MP0000477_abnormal_intestine_morphology0.66496850
115MP0005394_taste/olfaction_phenotype0.65320738
116MP0005499_abnormal_olfactory_system0.65320738
117MP0002925_abnormal_cardiovascular_devel0.65001760
118MP0000733_abnormal_muscle_development0.64692577
119MP0000049_abnormal_middle_ear0.64575507
120MP0002095_abnormal_skin_pigmentation0.64513683
121MP0000569_abnormal_digit_pigmentation0.62938192
122MP0005389_reproductive_system_phenotype0.62729023
123MP0000432_abnormal_head_morphology0.62615100
124MP0000427_abnormal_hair_cycle0.61914954
125MP0003806_abnormal_nucleotide_metabolis0.61592340
126MP0000371_diluted_coat_color0.61574779
127MP0002090_abnormal_vision0.60219487
128MP0002161_abnormal_fertility/fecundity0.58758388
129MP0008770_decreased_survivor_rate0.58538008
130MP0003935_abnormal_craniofacial_develop0.58399327
131MP0002254_reproductive_system_inflammat0.58100755
132MP0003861_abnormal_nervous_system0.57999755
133MP0001177_atelectasis0.57660315
134MP0000716_abnormal_immune_system0.56914675
135MP0005501_abnormal_skin_physiology0.56460608
136MP0003448_altered_tumor_morphology0.51993587
137MP0001186_pigmentation_phenotype0.51505708
138MP0003755_abnormal_palate_morphology0.51382447
139MP0003699_abnormal_female_reproductive0.50428800

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.46252059
2Chromsome breakage (HP:0040012)4.27524076
3Selective tooth agenesis (HP:0001592)3.84831290
4Chromosomal breakage induced by crosslinking agents (HP:0003221)3.83864676
5Ependymoma (HP:0002888)3.77693968
6Breast hypoplasia (HP:0003187)3.61184459
7Colon cancer (HP:0003003)3.55335563
8Abnormality of chromosome stability (HP:0003220)3.45985483
9Medulloblastoma (HP:0002885)3.41641724
10Patellar aplasia (HP:0006443)3.33922373
11Abnormality of the labia minora (HP:0012880)3.29477773
12Meckel diverticulum (HP:0002245)3.21932566
13Reticulocytopenia (HP:0001896)3.21898245
14Aplasia/Hypoplasia of the patella (HP:0006498)3.09641782
15Abnormality of the ileum (HP:0001549)3.07331378
16Abnormality of the preputium (HP:0100587)2.94949058
17Aplasia/Hypoplasia of the uvula (HP:0010293)2.87843312
18Absent radius (HP:0003974)2.82335843
19Ectopic kidney (HP:0000086)2.81943463
20Deviation of the thumb (HP:0009603)2.81828096
21Agnosia (HP:0010524)2.81698695
22Abnormality of the anterior horn cell (HP:0006802)2.78719367
23Degeneration of anterior horn cells (HP:0002398)2.78719367
24Proximal placement of thumb (HP:0009623)2.77129593
25Carpal bone hypoplasia (HP:0001498)2.74117605
26Myelodysplasia (HP:0002863)2.73112047
27Abnormal number of incisors (HP:0011064)2.70320179
28Rhabdomyosarcoma (HP:0002859)2.69839495
29Small intestinal stenosis (HP:0012848)2.67331519
30Duodenal stenosis (HP:0100867)2.67331519
31Aplasia involving forearm bones (HP:0009822)2.65904347
32Absent forearm bone (HP:0003953)2.65904347
33Absent thumb (HP:0009777)2.61744355
34Astrocytoma (HP:0009592)2.61643520
35Abnormality of the astrocytes (HP:0100707)2.61643520
36Increased nuchal translucency (HP:0010880)2.60911782
37Impulsivity (HP:0100710)2.56493531
38Volvulus (HP:0002580)2.54530367
39Oral leukoplakia (HP:0002745)2.48173770
4011 pairs of ribs (HP:0000878)2.45944111
41Abnormality of cells of the erythroid lineage (HP:0012130)2.45229141
42Glioma (HP:0009733)2.42101213
43Basal cell carcinoma (HP:0002671)2.41458941
44Abnormal number of erythroid precursors (HP:0012131)2.36122319
45Cortical dysplasia (HP:0002539)2.35032793
46Neoplasm of the pancreas (HP:0002894)2.33670436
47Facial hemangioma (HP:0000329)2.33117320
48Prominent nose (HP:0000448)2.32141800
49Sloping forehead (HP:0000340)2.32038122
50Abnormal lung lobation (HP:0002101)2.31933506
51Short 4th metacarpal (HP:0010044)2.30830365
52Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.30830365
53High pitched voice (HP:0001620)2.26993014
54Abnormality of the duodenum (HP:0002246)2.25423324
55Missing ribs (HP:0000921)2.24919191
56Abnormality of methionine metabolism (HP:0010901)2.24856172
57Cafe-au-lait spot (HP:0000957)2.24412012
58Duplicated collecting system (HP:0000081)2.20203573
59Abnormality of the carotid arteries (HP:0005344)2.19401004
60Amaurosis fugax (HP:0100576)2.19022775
61Bone marrow hypocellularity (HP:0005528)2.18879456
62Supernumerary spleens (HP:0009799)2.14802573
63Squamous cell carcinoma (HP:0002860)2.14625326
64Aplastic anemia (HP:0001915)2.13844320
65Horseshoe kidney (HP:0000085)2.12656289
66Abnormality of aspartate family amino acid metabolism (HP:0010899)2.12563337
67Short thumb (HP:0009778)2.11161344
68Neoplasm of the adrenal cortex (HP:0100641)2.10278442
69Atresia of the external auditory canal (HP:0000413)2.09419148
70Acute encephalopathy (HP:0006846)2.09133766
71Tracheoesophageal fistula (HP:0002575)2.09090691
72Aplasia/Hypoplasia of the sternum (HP:0006714)2.07913091
73Neoplasm of striated muscle (HP:0009728)2.05235495
74Rough bone trabeculation (HP:0100670)2.05054661
75Pancreatic islet-cell hyperplasia (HP:0004510)2.04313424
76Increased hepatocellular lipid droplets (HP:0006565)2.03222146
77Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.02261627
78Aplasia/hypoplasia of the humerus (HP:0006507)2.02110810
79Neoplasm of the colon (HP:0100273)2.01410532
80Abnormality of the calcaneus (HP:0008364)2.00952177
81Premature graying of hair (HP:0002216)1.99997789
82Abnormality of the pons (HP:0007361)1.99188536
83Neoplasm of the adrenal gland (HP:0100631)1.98546531
84Acute necrotizing encephalopathy (HP:0006965)1.98141816
85Hypoplasia of the pons (HP:0012110)1.96845426
86Increased CSF lactate (HP:0002490)1.95533611
87Cerebral hypomyelination (HP:0006808)1.94647977
88Nephroblastoma (Wilms tumor) (HP:0002667)1.94325443
89Clubbing of toes (HP:0100760)1.93481648
90Microvesicular hepatic steatosis (HP:0001414)1.93313419
91Neoplasm of the oral cavity (HP:0100649)1.90667817
92Choanal atresia (HP:0000453)1.90302857
93Trismus (HP:0000211)1.89100047
94Lymphoma (HP:0002665)1.88856964
95Embryonal renal neoplasm (HP:0011794)1.87374203
96Facial cleft (HP:0002006)1.87053078
97Abnormality of glycolysis (HP:0004366)1.85371221
98Increased serum pyruvate (HP:0003542)1.83829335
99Slender long bone (HP:0003100)1.83557731
100Multiple enchondromatosis (HP:0005701)1.82548869
101Intestinal atresia (HP:0011100)1.81856067
102Triphalangeal thumb (HP:0001199)1.81722306
103Thrombocytosis (HP:0001894)1.81674758
104Abnormality of serum amino acid levels (HP:0003112)1.81640999
105Abnormality of the renal collecting system (HP:0004742)1.81535846
106Rib fusion (HP:0000902)1.81478675
107Hypoplasia of the capital femoral epiphysis (HP:0003090)1.80728344
108Dandy-Walker malformation (HP:0001305)1.79053033
109Abnormality of DNA repair (HP:0003254)1.76200699
110Pancreatic cysts (HP:0001737)1.75293733
111Lipid accumulation in hepatocytes (HP:0006561)1.75103472
112Arteriovenous malformation (HP:0100026)1.73396541
113Macrocytic anemia (HP:0001972)1.72851225
114Abnormality of cochlea (HP:0000375)1.70189979
115Pallor (HP:0000980)1.70107619
116Ankle contracture (HP:0006466)1.69448213
117Biliary tract neoplasm (HP:0100574)1.69288467
118Overlapping toe (HP:0001845)1.68983928
119Gastrointestinal carcinoma (HP:0002672)1.68155701
120Malignant gastrointestinal tract tumors (HP:0006749)1.68155701
121Increased serum lactate (HP:0002151)1.68151627
122Shawl scrotum (HP:0000049)1.67653439
123Cellular immunodeficiency (HP:0005374)1.67632089
124Short humerus (HP:0005792)1.67186759
125Abnormal mitochondria in muscle tissue (HP:0008316)1.66524826
126Preaxial hand polydactyly (HP:0001177)1.66007306
127Hyperglycinemia (HP:0002154)1.65449557
128Abnormality of abdominal situs (HP:0011620)1.64794003
129Embryonal neoplasm (HP:0002898)1.64521731
130Astigmatism (HP:0000483)1.64464648
131Bifid tongue (HP:0010297)1.64141591
132Septo-optic dysplasia (HP:0100842)1.62879372
133Abnormality of midbrain morphology (HP:0002418)1.62108932
134Molar tooth sign on MRI (HP:0002419)1.62108932
135Pancreatic fibrosis (HP:0100732)1.61805809
136Small hand (HP:0200055)1.60378687
137Methylmalonic acidemia (HP:0002912)1.58514663
138Abnormality of the septum pellucidum (HP:0007375)1.58026409
139Pancytopenia (HP:0001876)1.57971432
140Cerebral edema (HP:0002181)1.57511712
141Ovarian neoplasm (HP:0100615)1.56814125
142Abnormal biliary tract physiology (HP:0012439)1.56808707
143Bile duct proliferation (HP:0001408)1.56808707
144Progressive macrocephaly (HP:0004481)1.54100416
145Hypoplastic pelvis (HP:0008839)1.52969559
146Bilateral microphthalmos (HP:0007633)1.52095089
147Mitochondrial inheritance (HP:0001427)1.51971582
148Megaloblastic anemia (HP:0001889)1.51619089

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.94618595
2BUB13.90992844
3WEE13.78819829
4SRPK13.17563592
5NEK23.02218711
6TTK2.87452947
7PBK2.55061118
8CDK122.52853667
9NEK12.49864487
10EIF2AK12.46640527
11TRIM282.40285786
12TSSK62.39402298
13NUAK12.23808854
14VRK22.20774884
15BRSK22.19453053
16PLK12.16577992
17PLK42.15788323
18SCYL22.05876253
19EEF2K1.97293301
20ATR1.96914319
21ACVR1B1.85506126
22STK101.83394085
23PASK1.76040969
24AURKB1.75235634
25PLK31.75165115
26RPS6KB21.71365743
27BMPR1B1.68541877
28MKNK11.68282360
29CDK71.66742004
30TESK21.65655499
31CHEK21.60240553
32BRSK11.58456324
33WNK31.56821718
34TAF11.48403331
35CHEK11.46165376
36TNIK1.45358715
37MAP3K81.45019086
38EPHA21.40701151
39CDK41.36580953
40VRK11.35041114
41EIF2AK31.34366767
42TLK11.30321545
43AURKA1.21591021
44BCR1.14307504
45PLK21.13404674
46MKNK21.11429932
47RPS6KA41.10344966
48PAK41.09033792
49ZAK1.07925289
50ATM1.07747671
51STK41.07563005
52TGFBR11.06143769
53MAP3K101.05437224
54BRD40.99632873
55* CDK20.98355748
56ALK0.98152456
57DYRK30.97393709
58STK30.97309716
59NME20.96506230
60PIM10.92943693
61MELK0.89593562
62FLT30.86245397
63PDK20.85667492
64ERBB30.85586611
65PKN20.83571872
66NME10.80178765
67CCNB10.78634088
68CDK10.78261177
69STK160.77547779
70LATS10.75856795
71CDK60.72155849
72CLK10.68311310
73CSNK2A20.66837388
74LRRK20.66274443
75LATS20.65446813
76MTOR0.64512844
77TTN0.63230974
78PAK10.63001630
79MAP2K30.62633590
80STK38L0.61528971
81CSNK1G10.61048046
82MAP4K10.60680948
83FRK0.58451989
84CSNK2A10.55492437
85PRKCI0.55378821
86OXSR10.51988231
87CDK80.51745503
88TESK10.51494434
89SIK30.50372035
90ERBB40.47528140
91YES10.43821551
92PRKDC0.43232574
93CSNK1G30.43160179
94CDK30.43038457
95CSNK1E0.41389380
96CSNK1D0.41305846
97MAP4K20.41144182
98MST40.40178914
99PAK20.40010956
100AKT20.39413034
101EIF2AK20.39365434
102PNCK0.37429694
103GRK60.36907347
104TAOK20.36779200
105STK390.36023844
106CSNK1A1L0.35759043
107CDK190.35325374
108MAPK140.34758652
109FGFR10.34211254
110WNK40.33935822
111DYRK20.33067717
112GRK10.32694241
113INSRR0.32554203
114MAP3K40.32271197
115CAMK1G0.31630464
116MAPKAPK30.31074919
117JAK30.30433077
118CSNK1G20.28978404
119CAMK1D0.27190518
120MINK10.25898004
121MET0.25400776
122MAP3K60.25285915
123PDGFRA0.25105097
124BRAF0.24673414
125KSR10.24195137
126AKT10.23599172
127MARK30.23525603
128CSF1R0.21917991
129STK240.21876938
130CDK11A0.21344409
131GSK3B0.21233589
132MAPK10.20704877
133CDK180.20680241
134RPS6KB10.20373962
135CDK150.20344600
136PIM20.20255219

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.08350347
2Mismatch repair_Homo sapiens_hsa034304.34236508
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.61038491
4Spliceosome_Homo sapiens_hsa030403.27579559
5* RNA transport_Homo sapiens_hsa030133.26510903
6Homologous recombination_Homo sapiens_hsa034403.21877304
7Base excision repair_Homo sapiens_hsa034103.21257912
8Cell cycle_Homo sapiens_hsa041103.11502614
9One carbon pool by folate_Homo sapiens_hsa006702.93985551
10Nucleotide excision repair_Homo sapiens_hsa034202.81322861
11Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.64581869
12RNA polymerase_Homo sapiens_hsa030202.59101199
13Non-homologous end-joining_Homo sapiens_hsa034502.50782577
14Fanconi anemia pathway_Homo sapiens_hsa034602.49545349
15Ribosome_Homo sapiens_hsa030102.28400005
16Proteasome_Homo sapiens_hsa030502.28004557
17Pyrimidine metabolism_Homo sapiens_hsa002402.11911893
18Protein export_Homo sapiens_hsa030602.11333691
19RNA degradation_Homo sapiens_hsa030182.02465594
20mRNA surveillance pathway_Homo sapiens_hsa030151.89825746
21p53 signaling pathway_Homo sapiens_hsa041151.89309821
22Propanoate metabolism_Homo sapiens_hsa006401.68219790
23Basal transcription factors_Homo sapiens_hsa030221.66457844
24Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.56669891
25Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.34070383
26Pyruvate metabolism_Homo sapiens_hsa006201.30111727
27Systemic lupus erythematosus_Homo sapiens_hsa053221.28448428
28Epstein-Barr virus infection_Homo sapiens_hsa051691.24235397
29Steroid biosynthesis_Homo sapiens_hsa001001.23984240
30Viral carcinogenesis_Homo sapiens_hsa052031.22347391
31Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.21236935
32Oocyte meiosis_Homo sapiens_hsa041141.16728987
33Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.15291174
34Purine metabolism_Homo sapiens_hsa002301.12365471
35Parkinsons disease_Homo sapiens_hsa050121.04546703
36Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.03739693
37Antigen processing and presentation_Homo sapiens_hsa046121.02145847
38Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.01745109
39Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.01020585
40Biosynthesis of amino acids_Homo sapiens_hsa012300.97765672
41MicroRNAs in cancer_Homo sapiens_hsa052060.95910832
42Oxidative phosphorylation_Homo sapiens_hsa001900.95365463
43Herpes simplex infection_Homo sapiens_hsa051680.94438355
44Fatty acid elongation_Homo sapiens_hsa000620.94154925
45Huntingtons disease_Homo sapiens_hsa050160.93510804
46HTLV-I infection_Homo sapiens_hsa051660.92386920
47Cyanoamino acid metabolism_Homo sapiens_hsa004600.91076833
48Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.90997794
49Small cell lung cancer_Homo sapiens_hsa052220.88696187
50Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.80943917
51Selenocompound metabolism_Homo sapiens_hsa004500.75742715
52Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.71411108
53Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.71244044
54Thyroid cancer_Homo sapiens_hsa052160.66024504
55Cysteine and methionine metabolism_Homo sapiens_hsa002700.65887566
56Pentose phosphate pathway_Homo sapiens_hsa000300.63068967
57Colorectal cancer_Homo sapiens_hsa052100.63031745
58Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.62563033
59Hippo signaling pathway_Homo sapiens_hsa043900.60444185
60Primary immunodeficiency_Homo sapiens_hsa053400.59220667
61Transcriptional misregulation in cancer_Homo sapiens_hsa052020.58283347
62Chronic myeloid leukemia_Homo sapiens_hsa052200.57921492
63Apoptosis_Homo sapiens_hsa042100.55917522
64Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.54910800
65Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.53834722
66Caffeine metabolism_Homo sapiens_hsa002320.53628024
67Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.53032557
68TGF-beta signaling pathway_Homo sapiens_hsa043500.51964832
69Hepatitis B_Homo sapiens_hsa051610.51566406
70Viral myocarditis_Homo sapiens_hsa054160.51564862
71Legionellosis_Homo sapiens_hsa051340.51163086
72Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.49395548
73Nitrogen metabolism_Homo sapiens_hsa009100.49249107
74Metabolic pathways_Homo sapiens_hsa011000.49143295
75N-Glycan biosynthesis_Homo sapiens_hsa005100.48978412
76Alcoholism_Homo sapiens_hsa050340.48706031
77Butanoate metabolism_Homo sapiens_hsa006500.48587611
78Notch signaling pathway_Homo sapiens_hsa043300.47298450
79Vitamin B6 metabolism_Homo sapiens_hsa007500.46945589
80Adherens junction_Homo sapiens_hsa045200.46931123
81Drug metabolism - other enzymes_Homo sapiens_hsa009830.46158845
82Central carbon metabolism in cancer_Homo sapiens_hsa052300.46074403
83Fatty acid metabolism_Homo sapiens_hsa012120.45397277
84Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.44111079
85Carbon metabolism_Homo sapiens_hsa012000.42043234
86Basal cell carcinoma_Homo sapiens_hsa052170.42036652
87Alzheimers disease_Homo sapiens_hsa050100.41783340
88Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.41777688
89Shigellosis_Homo sapiens_hsa051310.40829331
90Bladder cancer_Homo sapiens_hsa052190.40593337
91Folate biosynthesis_Homo sapiens_hsa007900.40071144
92Measles_Homo sapiens_hsa051620.37782156
93NF-kappa B signaling pathway_Homo sapiens_hsa040640.37578428
94HIF-1 signaling pathway_Homo sapiens_hsa040660.37078566
95Pathways in cancer_Homo sapiens_hsa052000.35965657
962-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.34481441
97Phototransduction_Homo sapiens_hsa047440.34116485
98Peroxisome_Homo sapiens_hsa041460.32721976
99Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.32590305
100Prostate cancer_Homo sapiens_hsa052150.31610490
101mTOR signaling pathway_Homo sapiens_hsa041500.29372245
102Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.28426019
103Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.28362799
104Pancreatic cancer_Homo sapiens_hsa052120.28187066
105Lysine degradation_Homo sapiens_hsa003100.28009591
106Non-small cell lung cancer_Homo sapiens_hsa052230.26008803
107Pentose and glucuronate interconversions_Homo sapiens_hsa000400.25494620
108Influenza A_Homo sapiens_hsa051640.25136212
109Hedgehog signaling pathway_Homo sapiens_hsa043400.24481843
110Sulfur metabolism_Homo sapiens_hsa009200.24474668
111Hematopoietic cell lineage_Homo sapiens_hsa046400.23788141
112Proteoglycans in cancer_Homo sapiens_hsa052050.23351963
113Glutathione metabolism_Homo sapiens_hsa004800.22960984
114Tryptophan metabolism_Homo sapiens_hsa003800.22366063
115Acute myeloid leukemia_Homo sapiens_hsa052210.22145430
116Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.20886904
117Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.20249225
118Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.20190242
119Fatty acid degradation_Homo sapiens_hsa000710.19672573
120Fructose and mannose metabolism_Homo sapiens_hsa000510.19264184
121Thyroid hormone signaling pathway_Homo sapiens_hsa049190.19042642
122PI3K-Akt signaling pathway_Homo sapiens_hsa041510.18470992
123Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.17886066
124Sulfur relay system_Homo sapiens_hsa041220.17748125
125Leukocyte transendothelial migration_Homo sapiens_hsa046700.16943433
126T cell receptor signaling pathway_Homo sapiens_hsa046600.15688220
127NOD-like receptor signaling pathway_Homo sapiens_hsa046210.15627990
128Melanoma_Homo sapiens_hsa052180.15315034
129FoxO signaling pathway_Homo sapiens_hsa040680.15163176
130Wnt signaling pathway_Homo sapiens_hsa043100.14313807
131beta-Alanine metabolism_Homo sapiens_hsa004100.14277058
132Arginine and proline metabolism_Homo sapiens_hsa003300.14090906
133Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.13182970
134Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.12240468
135Ether lipid metabolism_Homo sapiens_hsa005650.08349835
136Tight junction_Homo sapiens_hsa045300.07374725

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